chapter 13 the pns. peripheral nervous system (pns) all neural structures outside the brain sensory...
TRANSCRIPT
![Page 1: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/1.jpg)
Chapter 13
The PNS
![Page 2: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/2.jpg)
Peripheral Nervous System (PNS)
• All neural structures outside the brain
• Sensory receptors
• Peripheral nerves and associated ganglia
• Motor endings
![Page 3: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/3.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 13.1
Central nervous system (CNS) Peripheral nervous system (PNS)
Motor (efferent) divisionSensory (afferent)division
Somatic nervoussystem
Autonomic nervoussystem (ANS)
Sympatheticdivision
Parasympatheticdivision
![Page 4: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/4.jpg)
Sensory Receptors
• Specialized to respond to changes in their environment (stimuli)
• Activation results in graded potentials that trigger nerve impulses
• Sensation (awareness of stimulus) and perception (interpretation of the meaning of the stimulus) occur in the brain
![Page 5: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/5.jpg)
Classification of Receptors
• Based on:
• Stimulus type
• Location
• Structural complexity
![Page 6: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/6.jpg)
Classification by Stimulus Type
• Mechanoreceptors—respond to touch, pressure, vibration, stretch, and itch
• Thermoreceptors—sensitive to changes in temperature
• Photoreceptors—respond to light energy (e.g., retina)
• Chemoreceptors—respond to chemicals (e.g., smell, taste, changes in blood chemistry)
• Nociceptors—sensitive to pain-causing stimuli (e.g. extreme heat or cold, excessive pressure, inflammatory chemicals)
![Page 7: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/7.jpg)
From Sensation to Perception
• Survival depends upon sensation and perception
• Sensation: the awareness of changes in the internal and external environment
• Perception: the conscious interpretation of those stimuli
![Page 8: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/8.jpg)
Sensory Integration
• Levels of neural integration in sensory systems:
1. Receptor level—the sensor receptors
2. Circuit level—ascending pathways
3. Perceptual level—neuronal circuits in the cerebral cortex
![Page 9: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/9.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 13.2
1
2
3
Receptor level(sensory receptionand transmissionto CNS)
Circuit level(processing inascending pathways)
Spinalcord
Cerebellum
Reticularformation
Pons
Musclespindle
Jointkinestheticreceptor
Free nerveendings (pain,cold, warmth)
Medulla
Perceptual level (processing incortical sensory centers)
Motorcortex
Somatosensorycortex
Thalamus
![Page 10: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/10.jpg)
Processing at the Receptor Level
• In general sense receptors, the receptor potential and generator potential are the same thing
stimulus
receptor/generator potential in afferent neuron
action potential at first node of Ranvier
![Page 11: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/11.jpg)
Processing at the Receptor Level
• In special sense organs:
stimulus
receptor potential in receptor cell
release of neurotransmitter
generator potential in first-order sensory neuron
action potentials (if threshold is reached)
![Page 12: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/12.jpg)
Adaptation of Sensory Receptors
• Adaptation is a change in sensitivity in the presence of a constant stimulus
• Receptor membranes become less responsive
• Receptor potentials decline in frequency or stop
![Page 13: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/13.jpg)
Processing at the Circuit Level
• Pathways of three neurons conduct sensory impulses upward to the appropriate brain regions
• First-order neurons
• Conduct impulses from the receptor level to the second-order neurons in the CNS
• Second-order neurons
• Transmit impulses to the thalamus or cerebellum
• Third-order neurons
• Conduct impulses from the thalamus to the somatosensory cortex (perceptual level)
![Page 14: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/14.jpg)
Processing at the Perceptual Level
• Identification of the sensation depends on the specific location of the target neurons in the sensory cortex
• Aspects of sensory perception:
• Perceptual detection—ability to detect a stimulus (requires summation of impulses)
• Magnitude estimation—intensity is coded in the frequency of impulses
• Spatial discrimination—identifying the site or pattern of the stimulus (studied by the two-point discrimination test)
![Page 15: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/15.jpg)
Structure of a Nerve
• Connective tissue coverings include:
• Endoneurium—loose connective tissue that encloses axons and their myelin sheaths
• Perineurium—coarse connective tissue that bundles fibers into fascicles
• Epineurium—tough fibrous sheath around a nerve
![Page 16: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/16.jpg)
Copyright © 2010 Pearson Education, Inc. Figure 13.3b
Bloodvessels
Fascicle
Epineurium
Perineurium
Endoneurium
AxonMyelin sheath
(b)
![Page 17: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/17.jpg)
Classification of Nerves
• Most nerves are mixtures of afferent and efferent fibers and somatic and autonomic (visceral) fibers
• Pure sensory (afferent) or motor (efferent) nerves are rare
• Types of fibers in mixed nerves:
• Somatic afferent and somatic efferent
• Visceral afferent and visceral efferent
• Peripheral nerves classified as cranial or spinal nerves
![Page 18: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/18.jpg)
Ganglia
• Contain neuron cell bodies associated with nerves
• Dorsal root ganglia (sensory, somatic) (Chapter 12)
• Autonomic ganglia (motor, visceral) (Chapter 14)
![Page 19: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/19.jpg)
Cranial Nerves
• Twelve pairs of nerves associated with the brain
• Most are mixed in function; two pairs are purely sensory
• Each nerve is identified by a number (I through XII) and a name
“On occasion, our trusty truck acts funny—very good vehicle anyhow”
![Page 20: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/20.jpg)
Figure 13.5 (a)
Frontal lobe
Temporal lobe
InfundibulumFacialnerve (VII)Vestibulo-cochlearnerve (VIII)Glossopharyngealnerve (IX)Vagus nerve (X)Accessory nerve (XI)
Hypoglossal nerve (XII)
(a)
Filaments ofolfactory nerve (I)
Olfactory bulb
Olfactory tract
Optic chiasma
Optic nerve(II)
Optic tractOculomotornerve (III)Trochlearnerve (IV) Trigeminalnerve (V) Abducensnerve (VI)CerebellumMedullaoblongata
![Page 21: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/21.jpg)
Figure 13.5 (b)
*PS = parasympathetic(b)
Cranial nervesI – VI
I
II
III
IV
V
VI
Olfactory
Optic
Oculomotor
Trochlear
Trigeminal
Abducens
Yes (smell)
Yes (vision)
No
No
Yes (generalsensation)
No
No
No
Yes
Yes
Yes
Yes
No
No
Yes
No
No
No
Cranial nervesVII – XII
Sensoryfunction
Motorfunction
PS*fibers
Sensoryfunction
Motorfunction
PS*fibers
VII
VIII
IX
X
XI
XII
Facial
Vestibulocochlear
Glossopharyngeal
Vagus
Accessory
Hypoglossal
Yes (taste)
Yes (hearingand balance)
Yes (taste)
Yes (taste)
No
No
Yes
Some
Yes
Yes
Yes
Yes
Yes
No
Yes
Yes
No
No
![Page 22: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/22.jpg)
I: The Olfactory Nerves
• Arise from the olfactory receptor cells of nasal cavity
• Pass through the cribriform plate of the ethmoid bone
• Fibers synapse in the olfactory bulbs
• Pathway terminates in the primary olfactory cortex
• Purely sensory (olfactory) function
![Page 23: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/23.jpg)
Table 13.2
![Page 24: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/24.jpg)
II: The Optic Nerves
• Arise from the retinas
• Pass through the optic canals, converge and partially cross over at the optic chiasma
• Optic tracts continue to the thalamus, where they synapse
• Optic radiation fibers run to the occipital (visual) cortex
• Purely sensory (visual) function
![Page 25: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/25.jpg)
Table 13.2
![Page 26: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/26.jpg)
III: The Oculomotor Nerves
• Fibers extend from the ventral midbrain through the superior orbital fissures to the extrinsic eye muscles
• Functions in raising the eyelid, directing the eyeball, constricting the iris (parasympathetic), and controlling lens shape
![Page 27: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/27.jpg)
Table 13.2
![Page 28: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/28.jpg)
IV: The Trochlear Nerves
• Fibers from the dorsal midbrain enter the orbits via the superior orbital fissures to innervate the superior oblique muscle
• Primarily a motor nerve that directs the eyeball
![Page 29: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/29.jpg)
Table 13.2
![Page 30: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/30.jpg)
V: The Trigeminal Nerves
• Largest cranial nerves; fibers extend from pons to face
• Three divisions
• Ophthalmic (V1) passes through the superior orbital fissure
• Maxillary (V2) passes through the foramen rotundum
• Mandibular (V3) passes through the foramen ovale
• Convey sensory impulses from various areas of the face (V1) and (V2), and supplies motor fibers (V3) for mastication
![Page 31: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/31.jpg)
Table 13.2
![Page 32: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/32.jpg)
Table 13.2
![Page 33: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/33.jpg)
VI: The Abducens Nerves
• Fibers from the inferior pons enter the orbits via the superior orbital fissures
• Primarily a motor, innervating the lateral rectus muscle
![Page 34: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/34.jpg)
Table 13.2
![Page 35: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/35.jpg)
VII: The Facial Nerves
• Fibers from the pons travel through the internal acoustic meatuses, and emerge through the stylomastoid foramina to the lateral aspect of the face
• Chief motor nerves of the face with 5 major branches
• Motor functions include facial expression, parasympathetic impulses to lacrimal and salivary glands
• Sensory function (taste) from the anterior two-thirds of the tongue
![Page 36: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/36.jpg)
Table 13.2
![Page 37: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/37.jpg)
Table 13.2
![Page 38: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/38.jpg)
VIII: The Vestibulocochlear Nerves
• Afferent fibers from the hearing receptors (cochlear division) and equilibrium receptors (vestibular division) pass from the inner ear through the internal acoustic meatuses, and enter the brain stem at the pons-medulla border
• Mostly sensory function; small motor component for adjustment of sensitivity of receptors
![Page 39: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/39.jpg)
Table 13.2
![Page 40: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/40.jpg)
IX: The Glossopharyngeal Nerves
• Fibers from the medulla leave the skull via the jugular foramen and run to the throat
• Motor functions: innervate part of the tongue and pharynx for swallowing, and provide parasympathetic fibers to the parotid salivary glands
• Sensory functions: fibers conduct taste and general sensory impulses from the pharynx and posterior tongue, and impulses from carotid chemoreceptors and baroreceptors
![Page 41: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/41.jpg)
Table 13.2
![Page 42: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/42.jpg)
X: The Vagus Nerves
• The only cranial nerves that extend beyond the head and neck region
• Fibers from the medulla exit the skull via the jugular foramen
• Most motor fibers are parasympathetic fibers that help regulate the activities of the heart, lungs, and abdominal viscera
• Sensory fibers carry impulses from thoracic and abdominal viscera, baroreceptors, chemoreceptors, and taste buds of posterior tongue and pharynx
![Page 43: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/43.jpg)
Table 13.2
![Page 44: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/44.jpg)
XI: The Accessory Nerves
• Formed from ventral rootlets from the C1–C5 region of the spinal cord (not the brain)
• Rootlets pass into the cranium via each foramen magnum
• Accessory nerves exit the skull via the jugular foramina to innervate the trapezius and sternocleidomastoid muscles
![Page 45: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/45.jpg)
Table 13.2
![Page 46: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/46.jpg)
XII: The Hypoglossal Nerves
• Fibers from the medulla exit the skull via the hypoglossal canal
• Innervate extrinsic and intrinsic muscles of the tongue that contribute to swallowing and speech
![Page 47: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/47.jpg)
Table 13.2
![Page 48: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/48.jpg)
Spinal Nerves
• 31 pairs of mixed nerves named according to their point of issue from the spinal cord
• 8 cervical (C1–C8)
• 12 thoracic (T1–T12)
• 5 Lumbar (L1–L5)
• 5 Sacral (S1–S5)
• 1 Coccygeal (C0)
![Page 49: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/49.jpg)
Figure 13.6
CervicalnervesC1 – C8
ThoracicnervesT1 – T12
LumbarnervesL1 – L5
Sacral nervesS1 – S5
Coccygeal nerve Co1
Cervical plexus
Intercostalnerves
Cervicalenlargement
Lumbarenlargement
Cauda equina
Brachial plexus
Lumbar plexus
Sacral plexus
![Page 50: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/50.jpg)
Spinal Nerves: Roots
• Each spinal nerve connects to the spinal cord via two roots
• Ventral roots
• Contain motor (efferent) fibers from the ventral horn motor neurons
• Fibers innervate skeletal muscles)
![Page 51: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/51.jpg)
Spinal Nerves: Roots
• Dorsal roots
• Contain sensory (afferent) fibers from sensory neurons in the dorsal root ganglia
• Conduct impulses from peripheral receptors
• Dorsal and ventral roots unite to form spinal nerves, which then emerge from the vertebral column via the intervertebral foramina
![Page 52: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/52.jpg)
Figure 13.7 (a)
Dorsal rootganglion
Gray matterWhite matterVentral rootDorsal root
Dorsal andventral rootlets of spinal nerve
Dorsal ramusof spinal nerveVentral ramusof spinal nerve
Sympathetic trunkganglion
Spinal nerve
Rami communicantes
Anterior view showing spinal cord, associated nerves, and vertebrae. The dorsal and ventral roots arise medially as rootlets and join laterally to form the spinal nerve.
![Page 53: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/53.jpg)
Spinal Nerves: Rami
• Each spinal nerve branches into mixed rami
• Dorsal ramus
• Larger ventral ramus
• Meningeal branch
• Rami communicantes (autonomic pathways) join to the ventral rami in the thoracic region
![Page 54: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/54.jpg)
Figure 13.7 (b)
Dorsal ramus
Ventral ramus
Intercostal nerve
Spinal nerve
Rami communicantes
Dorsal rootganglion Dorsal rootVentral root
Sympathetic trunkganglion
Sternum
(b) Cross section of thorax showing the main roots and branches of a spinal nerve.
Branches of intercostalnerve
• Lateral cutaneous• Anterior cutaneous
![Page 55: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/55.jpg)
Cervical Plexus
• Formed by ventral rami of C1–C4
• Innervates skin and muscles of the neck, ear, back of head, and shoulders
• Phrenic nerve
• Major motor and sensory nerve of the diaphragm (receives fibers from C3–C5)
![Page 56: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/56.jpg)
Figure 13.8
Hypoglossalnerve (XII)
C1
C2
C3
C4
C5
Segmentalbranches
Lesser occipitalnerveGreater auricularnerve
Ansa cervicalis
Phrenic nerve
Supraclavicularnerves
Accessory nerve (XI)
Transversecervical nerve
Ventralrami:
Ventral rami
![Page 57: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/57.jpg)
Brachial Plexus
• Formed by ventral rami of C5–C8 and T1 (and often C4 and T2)
• It gives rise to the nerves that innervate the upper limb
• Major branches of this plexus:
• Roots—five ventral rami (C5–T1)
• Trunks—upper, middle, and lower
• Divisions—anterior and posterior
• Cords—lateral, medial, and posterior
![Page 58: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/58.jpg)
Figure 13.9 (a)
Upper
Middle Trunks
Lower
Roots (ventral rami):
Upper subscapular
Lower subscapular
Thoracodorsal
Medial cutaneousnerves of the armand forearm
Long thoracic
Medial pectoral
Lateral pectoral
Nerve tosubclaviusSuprascapular
Dorsal scapular
Posteriordivisions
Anteriordivisions
Lateral
PosteriorCords
Medial
Axillary
Musculo-cutaneousRadial
Median
Ulnar
Posteriordivisions
Trunks Roots
C4
C5
C6
C7
C8
T1
(a) Roots (rami C5 – T1), trunks, divisions, and cords
![Page 59: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/59.jpg)
Brachial Plexus: Nerves
• Axillary—innervates the deltoid, teres minor, and skin and joint capsule of the shoulder
• Musculocutaneous—innervates the biceps brachii and brachialis and skin of lateral forearm
• Median—innervates the skin, most flexors and pronators in the forearm, and some intrinsic muscles of the hand
• Ulnar—supplies the flexor carpi ulnaris, part of the flexor digitorum profundus, most intrinsic muscles of the hand, and skin of medial aspect of hand
• Radial—innervates essentially all extensor muscles, supinators, and posterior skin of limb
![Page 60: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/60.jpg)
Figure 13.9 (c)
Median nerve
Musculocutaneous nerve
Radial nerveHumerus
Ulna
Ulnar nerveMedian nerve
Radius
Radial nerve (superficial branch)
Superficial branch of ulnar nerveDorsal branch of ulnar nerve
Digital branch of ulnar nerveMuscular branchDigital branch
(c) The major nerves of the upper limb
Axillarynerve
Anteriordivisions
Posteriordivisions
Trunks Roots
![Page 61: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/61.jpg)
Lumbar Plexus
• Arises from L1–L4
• Innervates the thigh, abdominal wall, and psoas muscle
• Femoral nerve—innervates quadriceps and skin of anterior thigh and medial surface of leg
• Obturator nerve—passes through obturator foramen to innervate adductor muscles
![Page 62: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/62.jpg)
Figure 13.10
(a) Ventral rami and major branches of the lumbar plexus
Iliohypogastric
L1
L2
L3
L4
L5
Ilioinguinal
Genitofemoral
Lateral femoralcutaneous
Obturator
Femoral
Lumbosacraltrunk
Lateral femoralcutaneous
Anterior femoralcutaneousSaphenous
Obturator
IliohypogastricIlioinguinalFemoral
Ventral rami Ventralrami:
(b) Distribution of the major nerves from the lumbar plexus to the lower limb
![Page 63: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/63.jpg)
Sacral Plexus
• Arises from L4–S4
• Serves the buttock, lower limb, pelvic structures, and perineum
• Sciatic nerve
• Longest and thickest nerve of the body
• Innervates the hamstring muscles, adductor magnus, and most muscles in the leg and foot
• Composed of two nerves: tibial and common fibular
![Page 64: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/64.jpg)
Figure 13.11 (a)
SuperiorglutealLumbosacraltrunkInferiorgluteal
CommonfibularTibialPosteriorfemoralcutaneousPudendal
Sciatic
Ventral rami and major branches of the sacral plexus
L4
L5
S1
S2
S3
S4
S5
Co1
Ventral rami Ventral rami:
![Page 65: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/65.jpg)
Figure 13.11 (b)
Superior gluteal
Inferior gluteal
Common fibular
Deep fibular
Superficial fibular
Plantar branches
Tibial
Sural (cut)
Posterior femoralcutaneous
Pudendal
Sciatic
(b) Distribution of the major nerves from the sacral plexus to the lower limb
![Page 66: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/66.jpg)
Reflexes
• Inborn (intrinsic) reflex: a rapid, involuntary, predictable motor response to a stimulus
• Learned (acquired) reflexes result from practice or repetition,
• Example: driving skills
![Page 67: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/67.jpg)
Reflex Arc
• Components of a reflex arc (neural path)
1. Receptor—site of stimulus action
2. Sensory neuron—transmits afferent impulses to the CNS
3. Integration center—either monosynaptic or polysynaptic region within the CNS
4. Motor neuron—conducts efferent impulses from the integration center to an effector organ
5. Effector—muscle fiber or gland cell that responds to the efferent impulses by contracting or secreting
![Page 68: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/68.jpg)
Figure 13.14
Receptor
Sensory neuron
Integration center
Motor neuron
Effector
Spinal cord(in cross section)
Interneuron
Stimulus
Skin
1
2
3
4
5
![Page 69: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/69.jpg)
Spinal Reflexes
• Spinal somatic reflexes
• Integration center is in the spinal cord
• Effectors are skeletal muscle
• Testing of somatic reflexes is important clinically to assess the condition of the nervous system
![Page 70: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/70.jpg)
Figure 13.17 (1 of 2)
Stretched muscle spindles initiate a stretch reflex,causing contraction of the stretched muscle andinhibition of its antagonist.
When muscle spindles are activatedby stretch, the associated sensoryneurons (blue) transmit afferent impulsesat higher frequency to the spinal cord.
The sensory neurons synapse directly with alphamotor neurons (red), which excite extrafusal fibersof the stretched muscle. Afferent fibers alsosynapse with interneurons (green) that inhibit motorneurons (purple) controlling antagonistic muscles.
The events by which muscle stretch is damped
Efferent impulses of alpha motor neuronscause the stretched muscle to contract,which resists or reverses the stretch.
Efferent impulses of alpha motorneurons to antagonist muscles arereduced (reciprocal inhibition).
Initial stimulus(muscle stretch)
Cell body ofsensory neuron
Sensoryneuron
Muscle spindleAntagonist muscle
Spinal cord
12
3a 3b
![Page 71: Chapter 13 The PNS. Peripheral Nervous System (PNS) All neural structures outside the brain Sensory receptors Peripheral nerves and associated ganglia](https://reader034.vdocument.in/reader034/viewer/2022052401/56649e5d5503460f94b563f5/html5/thumbnails/71.jpg)
Figure 13.17 (2 of 2)
The patellar (knee-jerk) reflex—a specific example of a stretch reflex
Musclespindle
Quadriceps(extensors)
Hamstrings(flexors)
Patella
Patellarligament
Spinal cord(L2–L4)
Tapping the patellar ligament excitesmuscle spindles in the quadriceps.
The motor neurons (red) sendactivating impulses to the quadricepscausing it to contract, extending theknee.
Afferent impulses (blue) travel to thespinal cord, where synapses occur withmotor neurons and interneurons.
The interneurons (green) makeinhibitory synapses with ventral horn neurons (purple) that prevent theantagonist muscles (hamstrings) fromresisting the contraction of thequadriceps.
Excitatory synapseInhibitory synapse
+
–
1
2
3a
3b
1
2
3a3b 3b