chapter 46 animal reproduction. how does the human reproductive system work? mammals, including...
TRANSCRIPT
![Page 1: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/1.jpg)
Chapter 46
Animal Reproduction
![Page 2: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/2.jpg)
How does the human reproductive system work?
• Mammals, including humans produce gametes in paired organs called gonads
• In males: testes (singular = testis); produce sperm
• In females: ovaries; produce eggs
![Page 3: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/3.jpg)
Human male reproductive tract
See Fig. 46.10
![Page 4: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/4.jpg)
Human male reproductive tract
Testes (in scrotum) Sperm Testosterone
See Fig. 46.10
![Page 5: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/5.jpg)
Human male reproductive tract
Accessory structures Seminal vesicles Prostate gland Bulbourethral gland
(together produce semen)
See Fig. 46.10
![Page 6: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/6.jpg)
Human male reproductive tract
Accessory structures Epididymis (sperm storage)
See Fig. 46.10
![Page 7: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/7.jpg)
Accessory structures Vas deferens
(connects testes to urethra)
Human male reproductive tract
See Fig. 46.10
![Page 8: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/8.jpg)
Testes produce sperm & testosterone
Sperm production occurs
in seminiferous
tubules
See Fig. 46.12
![Page 9: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/9.jpg)
Testes produce sperm & testosterone
Sperm production occurs
in seminiferous
tubules
At puberty, testosterone
production begins
in interstitial cells
See Fig. 46.12
![Page 10: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/10.jpg)
Testes produce sperm & testosterone
Sperm production occurs
in seminiferous
tubules
Sertoli cells regulate
sperm production &
nourish developing
sperm
See Fig. 46.12
![Page 11: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/11.jpg)
Testes produce sperm & testosterone
Sperm production occurs
in seminiferous
tubules
Spermatozoa are
produced by
spermatogonia
See Fig. 46.12
![Page 12: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/12.jpg)
Spermatogenesis
Spermatogonia (2n) either undergo mitosis to produce new spermatogonia, or undergo meiosis to produce sperm (1n)
See Fig. 46.12
![Page 13: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/13.jpg)
Human sperm – almost no cytoplasm; carries male DNA to egg DNA
HeadNucleus – DNAAcrosome –
Enzymes
See Fig. 46.12
![Page 14: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/14.jpg)
Human sperm – almost no cytoplasm; carries male DNA to egg DNA
HeadNucleus – DNAAcrosome –
Enzymes
MidpieceMitochondria –
Energy
See Fig. 46.12
![Page 15: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/15.jpg)
Human sperm – almost no cytoplasm; carries male DNA to egg DNA
HeadNucleus – DNAAcrosome –
Enzymes
MidpieceMitochondria –
Energy
Tail Flagellum –
Propeller
See Fig. 46.12
![Page 16: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/16.jpg)
Human female reproductive tract
See Fig.
46.9
![Page 17: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/17.jpg)
Ovaries Eggs Estrogen / progesterone
Accessory structuresreceive & move sperm to egg & nourish developing embryo Vagina – receives sperm Fallopian tubes – site of fertilization Uterus – site of development of embryo
fimbriae
cervix
Fallopian tubes,
a.k.a. uterine tubes,
a.k.a. oviducts
ovaryuterus
vagina
Human female reproductive tract
See Fig.
46.9
![Page 18: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/18.jpg)
Ovaries Eggs Estrogen / progesterone
Accessory structuresreceive & move sperm to egg & nourish developing embryo Vagina – receives sperm Fallopian tubes – sites of fertilization Uterus – site of development of embryo
fimbriae
cervix
Fallopian tubes,
a.k.a. uterine tubes,
a.k.a. oviducts
ovaryuterus
vagina
Human female reproductive tract
See Fig.
46.9
![Page 19: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/19.jpg)
Oogenesis – formation of egg cells via meiosisIt has long been thought that women have
all their primary oocytes (halted at
Prophase of Meiosis I) by
the time they are born
See Fig.
46.11 & 46.13
![Page 20: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/20.jpg)
Monthly menstrual cycle coordinates:
1) maturation of several eggs2) release of one egg3) preparation of the uterine lining for possible pregnancy
![Page 21: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/21.jpg)
Hormonal control of the menstrual cycle:Hormones from the brain’s “master gland” (pituitary) initiate development of egg-bearing follicles in the ovary
![Page 22: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/22.jpg)
Hormonal control of the menstrual cycle: Estrogen produced by egg-bearing follicles stimulates the growth of the uterine lining
![Page 23: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/23.jpg)
Hormonal control of the menstrual cycle:Ovulation occurs on about day 14; remnants of ruptured follicle become the corpus luteum, which produces both estrogens and progesterone
![Page 24: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/24.jpg)
Hormonal control of the menstrual cycle: Combination of estrogens + progesterone:
1) Inhibits hormone release from pituitary, preventing development of more follicles2) Stimulates further growth of uterine lining
![Page 25: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/25.jpg)
Hormonal control of the menstrual cycle: If pregnancy does not begin: 1) The corpus luteum breaks down2) Estrogens & progesterone levels fall3) Uterine lining is shed as menstrual flow
![Page 26: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/26.jpg)
Fertilization may lead to pregnancy… Sperm deposited in the vagina during copulation swim through the uterus into the Fallopian tubes,
where they may encounter an egg
Oocyte (egg)Oocyte (egg)
SpermSperm
Sperm
Sperm
![Page 27: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/27.jpg)
Fertilization may lead to pregnancy… Sperm release enzymes that break down the barriers around the egg (corona radiata and
zona pelucida)
Corona radiata – layer of accessory cells around egg
Zona pellucida – jelly-like layer
around egg
oocyte
![Page 28: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/28.jpg)
Fertilization may lead to pregnancy… Fusion of the nuclei of an egg and one sperm
(fertilization) produces a zygote
Corona radiata – layer of accessory cells around egg
Zona pellucida – jelly-like layer
around egg
oocyte
![Page 29: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/29.jpg)
If pregnancy begins, the embryo secretes a hormone that prevents the breakdown of the
corpus luteum
![Page 30: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/30.jpg)
Corpus luteum continues to produce estrogens and progesterone, so the uterine lining continues
to grow and develop
![Page 31: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/31.jpg)
Most pregnancy tests detect the presence of a hormone produced by the embryo – and present
in the woman’s urine
![Page 32: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/32.jpg)
Fetal development…• The inner wall of the uterus together with embryonic tissues
become the placenta, which transfers oxygen, carbon dioxide, nutrients and wastes between the mother and the developing fetus
Umbilical cord
Fetalcapillaries
Maternal bloodpools
Umbilical cord
Maternal portionof placenta
Fetal portion ofplacenta (chorion)
Maternalarteries
Maternalveins
Figure 46.16
Placenta
Uterus
![Page 33: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/33.jpg)
Two basic reproductive modes
• Asexual reproduction– Requires only one parent
– Offspring are genetically identical to parent and to each other
• Sexual reproduction– Requires meiotic cell division in two parents
– Produces genetically variable offspring, with different combinations of parental genes
![Page 34: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/34.jpg)
Asexual reproduction: budding
Adult
Bud
• Occurs in sponges and some cnidarians (e.g., Hydra)
• Miniature animal begins as a bud on an adult, then becomes independent
Budding in Hydra
![Page 35: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/35.jpg)
Asexual reproduction: fission followed by regeneration
• Occurs in some cnidarians, flatworms and some segmented worms (annelids)
• Body splits into two or more pieces
• Each piece regenerates any missing body parts Fission in a
sea anemone
![Page 36: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/36.jpg)
FlatwormFlatworm cinches in cinches in
twotwo
Posterior Posterior half with half with no headno head
Grows Grows new headnew head
Anterior Anterior half with half with no tailno tail
Grows Grows new tailnew tail
Asexual reproduction:fission followed by regeneration
![Page 37: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/37.jpg)
Asexual reproduction:parthenogenesis
• In rotifers, as well as some insects, fish, amphibians and reptiles the eggs produced by females develop directly into adults without being fertilized by sperm
• This process is called parthenogenesis
![Page 38: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/38.jpg)
Aphid
Babyaphid
![Page 39: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/39.jpg)
Whiptail lizard
![Page 40: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/40.jpg)
Queen bee(fertile female;
diploid)
Worker bee(sterile female;
diploid)
Drone(fertile male;
haploid)
![Page 41: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/41.jpg)
Sexual reproduction requires fusion of sperm & egg
![Page 42: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/42.jpg)
Sexual reproduction in animals• Requires the production of gametes (egg
and sperm), which are haploid (1n) cells
• Gametes are produced from diploid (2n) cells by meiosis
• Fusion of egg and sperm (fertilization) produces a diploid zygote, which divides by mitosis and develops into new diploid animal
![Page 43: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/43.jpg)
Some organisms are hermaphrodites; they produce both eggs and sperm & can self-fertilize
E.g., tapeworm
![Page 44: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/44.jpg)
Some hermaphrodites cannot self-fertilize and so must exchange
sperm to fertilize each other’s eggs
E.g., some snails
![Page 45: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/45.jpg)
Most animals are dioecious, with separate females and males
Female mallard Male mallard
![Page 46: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/46.jpg)
• Females produce large, non-motile eggs, that contain food reserves
• Males produce small, motile sperm, with no food reserves
Most animals are dioecious, with separate females and males
![Page 47: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/47.jpg)
External fertilization: Spawning
• Union of sperm and egg takes place outside the bodies of the parents
• External fertilization is common in animals that live in water
• Release of sperm and eggs into the water is called spawning
• Release is often synchronized using environmental cues (e.g., seasons, tides)
![Page 48: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/48.jpg)
Grunion spawning
![Page 49: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/49.jpg)
Coral spawning
![Page 50: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/50.jpg)
External fertilization: Amplexus• Male frogs mount females in a pose called
amplexus
• Female releases eggs and male then releases a cloud of sperm over them
![Page 51: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/51.jpg)
Internal fertilization• Important adaptation to life on land
• Fertilization occurs inside female’s body
• Copulation: Male deposits sperm directly into female’s reproductive tract
![Page 52: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/52.jpg)
Internal fertilization
Damselflies mating
![Page 53: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/53.jpg)
Chapter 47
Animal Development
![Page 54: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/54.jpg)
Growth, differentiation, and morphogenesis occur during the development of multicellular organisms
E.g., from a single-celled zygote (about the size of a period on a printed page) to a fully mature adult human
![Page 55: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/55.jpg)
Growth, differentiation, and morphogenesis occur during the development of multicellular organisms
E.g., from a single-celled zygote (about the size of a period on a printed page) to a fully mature adult human
Cell division alone would simply result in a growing mass of identical cells
![Page 56: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/56.jpg)
Development produces cells of different types, arranged in a particular three-spatial dimensional pattern and appearing in
a particular temporal pattern
Fig. 21.4
![Page 57: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/57.jpg)
Development produces cells of different types, arranged in a particular three-spatial dimensional pattern and appearing in
a particular temporal pattern
Fig. 21.4
![Page 58: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/58.jpg)
All of the autosomal cells of a given organism share the same genetic material (the organism’s genome)
Fig. 21.4
![Page 59: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/59.jpg)
Differentiation and morphogenesis result from differences in gene expression among cells, i.e., different portions of the
common genome are expressed in different cells
Fig. 21.4
![Page 60: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/60.jpg)
Differentiation occurs as tissue-specific proteins are produced, some of which are transcription factors
Fig. 21.4
![Page 61: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/61.jpg)
E.g., skeletal muscle cells; Fig. 21.10
Differentiation occurs as tissue-specific proteins are produced, some of which are transcription factors
![Page 62: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/62.jpg)
Transcription factors = regulatory proteins that can “switch on” developmental cascades by causing gene expression
E.g., skeletal muscle cells; Fig. 21.10
![Page 63: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/63.jpg)
Transcription factors = regulatory proteins that can “switch on” developmental cascades by causing gene expression
E.g., skeletal muscle cells; Fig. 21.10
![Page 64: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/64.jpg)
Transcription factors = regulatory proteins that can “switch on” developmental cascades by causing gene expression
E.g., skeletal muscle cells; Fig. 21.10
![Page 65: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/65.jpg)
E.g., stem cells for medical research and treatment; Fig. 21.9
Differentiation occurs as tissue-specific proteins are produced, some of which are transcription factors
![Page 66: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/66.jpg)
This example also illustrates the critical nature of the environment for a cell’s differentiation
E.g., stem cells for medical research and treatment; Fig. 21.9
![Page 67: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/67.jpg)
The environment determines which genes are expressed
E.g., stem cells for medical research and treatment; Fig. 21.9
![Page 68: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/68.jpg)
The internal and external environments influence gene expression
E.g., differences in the chemical constitution of a cell’s cytoplasm received from the parent cell cause divergent
differentiation in the daughter cells
Fig.21.11
![Page 69: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/69.jpg)
E.g., differences in the chemical constitution of a cell’s cytoplasm received from the parent cell cause divergent
differentiation in the daughter cells
Fig.47.24
The internal and external environments influence gene expression
![Page 70: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/70.jpg)
Fig.21.11
E.g., induction by signals from other cells causes selective gene expression
The internal and external environments influence gene expression
![Page 71: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/71.jpg)
Fig.47.25
Consider this classic example from Hans Spemann and Hilde
Mangold (1920s)
A piece from the dorsal side of a nonpigmented
newt gastrula was transplanted to the
ventral side of a pigmented gastrula
E.g., induction by signals from other cells causes selective gene expression
The internal and external environments influence gene expression
![Page 72: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/72.jpg)
Consider this classic example from Hans Spemann and Hilde
Mangold (1920s)
A piece from the dorsal side of a nonpigmented
newt gastrula was transplanted to the
ventral side of a pigmented gastrula
A secondary embryo developed on the primary
embryo’s ventral side
Fig.47.25
The internal and external environments influence gene expression
![Page 73: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/73.jpg)
The secondary embryo’s tissues were largely
derived from the primary embryo’s gastrula,
indicating that induction from the cells of the
small piece of transplanted non-
pigmented gastrular tissue “triggered” or
“switched on” the developmental cascade
that caused the development of the secondary embryo
Fig.47.25
The internal and external environments influence gene expression
![Page 74: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/74.jpg)
Fig.47.19
As specific genes are expressed, owing to the particular environment a cell experiences, tissue-specific proteins are
produced that cause changes in a differentiating cell
E.g., a tube, such as the neural tube in vertebrates, may form from cells in a single layer becoming wedge shaped
![Page 75: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/75.jpg)
As specific genes are expressed, owing to the particular environment a cell experiences, tissue-specific proteins are
produced that cause changes in a differentiating cell
E.g., a tube, such as the neural tube in vertebrates, may form from cells in a single layer becoming wedge shaped
In this example, tissue-specific
proteins including those
forming microfilaments
and microtubules,
cause the cells to change
shape
Fig.47.19
![Page 76: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/76.jpg)
As specific genes are expressed, owing to the particular environment a cell experiences, tissue-specific proteins are
produced that cause changes in a differentiating cell
E.g., a tube, such as the neural tube in vertebrates, may form from cells in a single layer becoming wedge shaped
Fig.47.19
In this example, tissue-specific
proteins including those
forming microfilaments
and microtubules,
cause the cells to change
shape
![Page 77: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/77.jpg)
As specific genes are expressed, owing to the particular environment a cell experiences, tissue-specific proteins are
produced that cause changes in a differentiating cell
E.g., a tube, such as the neural tube in vertebrates, may form from cells in a single layer becoming wedge shaped
Fig.47.19
In this example, tissue-specific
proteins including those
forming microfilaments
and microtubules,
cause the cells to change
shape
![Page 78: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/78.jpg)
A major difference in morphogenesis in plants and animals is that only in animals do some cells change position
within the developing organism
In this example, cell shape and positional changes result in a sheet of cells becoming narrower and longer
Fig.47.20
![Page 79: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/79.jpg)
As cells change shape and position, embryologists have used dyes to create fate maps of regions of cells (Fig. 47.23a)
and individual cells (Fig. 47.23b)
Fig.47.23
![Page 80: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/80.jpg)
Developmental biologists have also discovered that molecular cues convey positional information to cells,
informing cells of their positions relative to other cells in the developing body
For example, cell-specific gene expression in this chick’s wing depended and continues to depend upon cells’
positions relative to other cells in 3D
Fig.47.26
![Page 81: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/81.jpg)
Vertebrate limbs, like a chick’s wing, begin as bumps of tissue known as limb buds
Fig.47.26
![Page 82: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/82.jpg)
Two main organizer regions of cells send chemical signals that form concentration gradients that define two of the main
spatial axes of the developing limb
The apical ectodermal ridge (AER) defines the proximal-distal axis
The zone of polarizing activity (ZPA) defines the anterior-posterior axis
Fig.47.26
![Page 83: Chapter 46 Animal Reproduction. How does the human reproductive system work? Mammals, including humans produce gametes in paired organs called gonads](https://reader036.vdocument.in/reader036/viewer/2022062307/551a63d555034643688b4c13/html5/thumbnails/83.jpg)
Development isn’t restricted to embryonic and juvenile states; it occurs throughout the lifetime of an organism…
E.g., in all organisms some cells are continually being replaced (e.g., red blood cells in humans)
E.g., in humans one’s behavior changes throughout one’s lifetime