ciliates: cell-tainerâ„¢ an excellent expression system for the

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Ciliates: An excellent expression system for the production of biopharmaceuticals. Cilian uses the unique features of single cell eukaryotic micro-organism, the Ciliate Tetrahymena, in order to overcome the drawbacks of common production technologies. Currently the largest part of all complex therapeutic proteins is produced in mammalian cells. Ciliates exhibit numerous advantages against these so far used conventional mammalian cell systems. The biggest advantages of production proteins in Ciliates are: 1. Prize: Production with lower cost of goods 2. Quality: Production in absence of biosafety issues 3. Efficacy: Proteins with optimized features (post-translational modification) Bioceros BV Remco Brandt, M.Sc. (CEO) Yalelaan 46, 3584 CM UTRECHT The Netherlands www.bioceros.com [email protected]

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Pioneers in international businessPioneers in international business

Ciliates:An excellent expression system for the production of biopharmaceuticals.Cilian uses the unique features of single cell eukaryotic micro-organism, the Ciliate Tetrahymena, in order to overcome the drawbacks of common production technologies. Currently the largest part of all complex therapeutic proteins is produced in mammalian cells. Ciliates exhibit numerous advantages against these so far used conventional mammalian cell systems. The biggest advantages of production proteins in Ciliates are: 1. Prize: Production with lower cost of goods 2. Quality: Production in absence of biosafety issues 3. Efficacy: Proteins with optimized features (post-translational modification)

CELL-tainer™The ultimate disposable bioreactor

Innovative bioreactor with superior kla values facilitating microbial and mammalian cultures, no shear issues and linear scaleable from 2L to 1200L

Benefits

• superior mass transfer properties • linear scaleable • flexible culture volume in one bag applying removable strips

Bioceros BVRemco Brandt, M.Sc. (CEO)Yalelaan 46, 3584 CM UTRECHTThe [email protected]