clinical history 42 year-old fillpino male who had a reported history of persistent eosinophilia for...
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Clinical History
• 42 year-old Fillpino male who had a reported history of persistent eosinophilia for many years and was evaluated at an outside hospital without treatment
• In October 2008, the patient was also found to have right axillary mass (LN) and was biopsied at that hospital and had subsequently completed 4 cycles of chemotherapy since then
• The patient was transferred to COHNMC for further management
Pathology in COH
• After admission in COH
• The outside axillary LN biopsy was reviewed and additional immunohistochemical studies were performed
• A bone marrow biopsy was performed and reviewed at COH
Right axillary LN biopsy in 10/2008
CD3
TDT
CD4 CD8
Peripheral blood and bone marrow biopsy in 11/2008
MPO
CD117 CD117
In 12/2009, the patient suddenly developed marked leukecytosis and numerous circulating blasts, leading
to a prompt peripheral blood and bone marrow examination
TdT PAX-5