clinical uses of enzymes, diagnostic importance of enzymes
TRANSCRIPT
Enzymes in clinical use
DIAGNOSTIC VALUE OF SERUM ENZYMES
CARDIAC BIOMARKERS
CK-MB AST LDH
ENZYME PROFILE IN LIVER DISEASE
ALTALP
obstructive
γGThepatobi
liary
ALT Alanine aminotransaminase ↑ in acute liver damage
ALP Alkaline phosphatase Bone & liver↑in rickets, hyperparathyroidism, Paget disease, obstructive
jaundice, osteoblastic sarcoma.
γGTGamma glutamyl transpeptidase↑ in hepatobiliary obstruction, alcohol induced liver disease
ALP ↑ in bone disease ACID PHOSPHATASE ↑ in prostatic carcinoma with
metastasis CREATINE KINASE(MM) ↑ in muscle disease AMYLASE ↑ in parotitis, acute pancreatitis