connective tissues -...
TRANSCRIPT
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CONNECTIVE TISSUES
Department of Histology, Embryology, and Cytologyof the General Medicine Faculty, RNMR
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СОЕДИНИТЕЛЬНЫЕ ТКАНИ
Ткани со специальнымисвойствами
Рыхлая Плотная
Волокнистые соединительные
ткани
Оформленная
Неоформленная
Слизистая
Белая Бурая
Ретикулярная
Пигментная
Жировая
Скелетные ткани
Гиалиновая
Волокнистая
Эластическая
Хрящевые
Грубо-волокнистая
Пластинчатая
Костные
Дентин
Цемент
Эмбриональные
Мезенхима
All tissues of the internal environment have several features in common-origin from mesenchyme,-abundant extracellular matrix-separated arrangement of resident cells-lack of permanent cell junctions
CONNECTIVE TISSUES
TISSUES OF THE INTERNAL ENVIRONMENT (CONNECTIVE)
Fibrous connective tissues (connective
tissues proper)
Connective tissues with special properties
Embryonic/fetal Skeletal
Loose Dense
Regular
Irregular
Reticular
Pigment
Adipose
White Brown
Mucous
Mesenchyme
Cartilage Bone
Reticulo-fibrous
Lamellar
Dentin
Cementum
Hyaline
Elastic
Fibrocartilage
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FIBROUS CONNECTIVE TISSUES
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collagen fiber
elastic fiber
fibroblast
histiocyte
mast cell
lymphocyte
ground substance
LOOSE FIBROUS CONNECTIVE TISSUE
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fibroblastcollagen fiber plasma cells
mast cell
endothelial cell
macrophage
lipocytes lymphocyteseosinophil
elastic fiber
LOOSE FIBROUS CONNECTIVE TISSUE
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LOOSE FIBROUS CONNECTIVE TISSUE
Fibrocyte Mast cell
Collagen fiberBranching elastic fiber
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Slide №55 “Loose fibrous connective tissue (whole mount)”Staining: iron hematoxylin
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Slide №55 “Loose fibrous connective tissue (whole mount)”Staining: iron hematoxylin
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Slide №55 “Loose fibrous connective tissue (whole mount)”Staining: iron hematoxylin
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Cells of the loose fibrous connective tissue:I- fibroblast, II- fibrocyte, III- histiocyte, IV- mast cell, V- plasma cell, VI- adipocyte, VII- pigment cell.1- specific granules, 2- lysosomes, 3- lamellopodia, 4- lipid droplet.
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adventitial cell
endothelial cell of the capillary
basement membrane
pericyte
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PRODUCTION OF COLLAGEN
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Structure of a collagen fiberА- collagen molecule composed of three polypeptides,Б- collagen microfibril, В- collagen fibril, Г- collagen fiber
PRODUCTION OF COLLAGEN
Formation of crosslinksbetween collagen molecules
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DesmosineDesmosine
1 to 10 µm
Elastin molecule
DEFORMATIONS
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GROUND SUBSTANCE
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Fibroblasts
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Mast cells
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Plasma cells
Epithelium of an intestinal villus
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Macrophage
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PericyteEndothelial cell
Pigment cell (melanocyte)
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Macrophages
Macrophagesand fibroblasts
Mast cells
Plasma cells
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Dense fibrous irregular connective tissue
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Dense fibrous regular connective tissue. Tendon, longitudinal section
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Б
2
А- bundle of the second order;Б- bundles of the first order; 1- endotendinium; 2- nuclei of fibrocytes; 3- collagen fibers
Dense fibrous regular connective tissue. Tendon, longitudinal section
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1- bundle of the first order, 2- nuclei of fibrocytes, 3- endotendinium, 4- bundle of the second order,5- peritendinium, 6-epitendinium
Dense fibrous regular connective tissue. Tendon
Cross section Longitudinal section
3 65
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Slide №62 “Dense fibrous regular connective tissue of a tendon, longitudinal section” Staining: H&E
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Slide №62a “Dense fibrous regular connective tissue of a tendon, cross section” Staining: H&E
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RETICULAR TISSUE
reticular fibers
lymphocytesreticular cells
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Slide №59 “Reticular tissue, section of a lymph node” Staining: H&E
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ADIPOSE TISSUE
Mesenchymal cell
Fibroblast Lipoblast
Lipoblast
Unilocular adipose cell
Multilocular adipose cell
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Slides №60, 61 “Dense fibrous irregular connective tissue of the dermis, section of the thick skin” Staining: H&E
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Mucous tissue
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Differons of connective tissues
hemopoietic stem cell
osteogenic cell
labrogenic cell
multivesicular univesicular
brown fat cell white fat cell
mast cell
fibroblast
fibrocyte
chondroblast
osteoblast
premonocyte
prelymphocyte
prolymphocyte
В lymphocyteт
plasmocyte (from B cells only)
monocyte
promonocyte
macrophage
chondrogenic cell
MESENCHYME
fibroclast
myofibroblast
fibrogenic cell
osteocyte
chondrocyte histiocyte
osteoclast
chondroclast
lipogenic cell
adventitial cell
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Hyaline cartilage Elastic cartilage Fibrocartilage
CARTILAGE TISSUE
1 – perichondrium: a) blood vessels; 2-young chondrocytes; 3-isogenous groups;4-elastic fibers; 5-chondrin fibers
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I- perichondrium: 1- external fibrous layer,2- internal cellular layer (chondrogenic layer); II- zone of young cartilage: 3- single chondrocytes; III- zone of mature cartilage: 4- isogenous groups of chondrocytes; 5- extracellular matrix
Hyaline cartilage in cross section Zone of mature cartilage
1- isogenous groups of chondrocytes; 2- extracellular matrix; 3- territorial matrix; 4- interterritorial matrix
HYALINE CARTILAGE TISSUE
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Slide №63 “Hyaline cartilage, cross section of a rib” Staining: H&E
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I- perichondrium: 1- single chondrocytes; 2- isogenous groups of chondrocytes (columns); 3- extracellular matrix with elastic fibers
1- isogenous groups of chondrocytes (columns); 2- elastic fibers of the matrix
ELASTIC CARTILAGE TISSUE
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Slide №64 “Elastic cartilage, section of an auricle” Staining: H&E
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1- chondrocytes, 2- bundles of collagen fibers
FIBROCARTILAGE TISSUE
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Slide №65 “Fibrocartilage, section of an intervertebral disk” Staining: H&E
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Slide №65 “Fibrocartilage, section of an intervertebral disk” Staining: H&E
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TASKS FOR SELF-STUDYING
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