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    Pre-Hospital CPAP

    What the EMS MedicalDirector should know

    Keith Wesley, MDWisconsin State EMS Medical Director

    [email protected]

    mailto:[email protected]:[email protected]
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    Objectives

    Review the goal & physiology of CPAP

    Discuss the indications and

    contraindications for CPAP use

    Review the literature supporting CPAP use

    Explore the role of CPAP use by pre-

    hospital providersDiscuss the methods for implementing

    pre-hospital CPAP

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    The Goal of CPAP?

    Reduce the need for pre-

    hospital intubation!

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    CPAP vs. Intubation

    CPAP

    Non-invasive

    Easily discontinued

    Easily adjustedUse by EMT-B

    Minimal complications

    Does not require sedation

    Comfortable

    Intubation

    Invasive

    Intubated stays intubated

    Requires highly trainedpersonnel

    Significant complications

    Can require sedation or

    RSIPotential for infection

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    The Problem

    Congestive Heart Failure Incidence 10 per 1000 patient (over age 65) transports

    25% of Medicare Admissions

    Average LOS is 6.7 days 6.5 million hospital days

    Those who get intubated have significantly longer LOS

    33% get intubated without non-invasive pressure

    support Intubated patients have 4 times the mortality of non-intubated patients

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    The Problem

    CHF/Pulmonary Edema

    Interstitial fluid interferes with gas exchange

    (ventilation and oxygenation)

    Increased myocardial workload resulting in

    higher oxygen demands (many of these

    patients are suffering ischemic heart disease)

    Traditional therapies designed to reduce pre-load and after-load as well as remove

    interstitial fluid

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    The Problem

    COPD/Asthma

    Increased work of breathing

    Hypercarbic (ventilation issue)

    Traditional therapies involve brochodilators

    which require adequate ventilation

    Higher mortality rate if intubated

    Difficult to wean once intubated

    Extremely difficult patient to intubate in the

    pre-hospital arena usually requires RSI

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    Physiology of CPAP

    Airway pressure maintained at set level

    throughout inspiration and expiration

    Maintains patency of small airways and

    alveoli

    Improves gas exchange

    Improves delivery of bronchodilatorsMoves extracellular fluid into vasculature

    Reduces work of breathing

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    Supporting Literature

    JAMA December 28, 2005 Noninvasive

    Ventilation in Acute Cardiogenic Edema,

    Massip et. al.

    Meta-analysis of studies with good to

    excellent data

    45% reduction in mortality

    60% reduction in need to intubate

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    Supporting Literature

    Reviews in Cardiovascular Medicine, vol. 3 supl. 4 2002,Role of Noninvasive Ventilation in the Management of

    Acutely Decompensated Heart Failure

    Though BLPAP has theoretical advantages over CPAP,there are questions regarding its safety in a setting ofCHF. The Key to success in using NIV to treat severeCHF is proper patient selection, close patient monitoring,proper application of the technology, and objective

    therapeutic goals. When used appropriately, NIV can bea useful adjunct in the treatment of a subset of patientswith acute CHF at risk for endotracheal intubation.

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    Supporting Literature

    Brochard (French abstract) Noninvasive

    ventilation for acute exacerbations of

    COPD

    can reduce the need for intubation, LOS

    in hospital, and mortality rate

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    BiPAP vs CPAP

    European Respiratory Journal, vol. 15

    2000 Effects of biphasic positive airway

    pressure in patients with chronic

    obstructive lung disease

    BiPAP resulted in overall higher intrathoracic

    pressures reduces myocardial perfusion

    BiPAP resulted in lower tidal volumes BiPAP resulted in higher WOB

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    Pre-hospital CPAP

    PEC 2000 NAEMSP Abstract, Pre-hospital use of CPAPfor presumed pulmonary edema: a preliminary caseseries, Kosowsky, et. al.

    19 patients

    Mean duration of therapy 15.5 minutesOxygen sat. rose from 83.3% to 95.4%

    None were intubated in the field

    2 intubated in the ED

    5 subsequently intubated in hospitalPre-hospital CPAP is feasible and may avert the needfor intubation

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    UTMB Experience

    Dr. Jeffery Miller UT Galveston

    IRB approval through UTMB

    6 hours didactic instruction

    Recognize CHF trial limited to CHF

    Differentiate CHF, COPD, Asthma &Bronchitis

    2 hours clinical trainingInstruction on assessment most importantreason for success

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    UTMB Experience

    Data Summary Sept. 1996 May 1997 Total intubations 22

    Hospital stay 14.8 days

    ICU admission 100%

    Data Summary Sept. 1997 May 1998 CPAP 50

    Total intubations 8 (15%)

    CPAP failures 4 (8%) Hospital stay 8 days

    ICU admission 48%

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    Wisconsin EMTBasic Experience

    Question: Can EMT-Basics apply CPAP

    as safely as Paramedics?

    50 EMT-Basic services

    2 hour didactic, 2 hour lab, written and

    practical test

    Required data collectionCompared to same data collected by ALS

    services during same period

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    Wisconsin EMTBasic Experience

    Required data collection

    Criteria used to apply CPAP

    Absence of contraindications

    Q 5 min. vital signs including oxygen sats.

    Subjective dyspnea score

    Because EMTBasics dont diagnose a

    unique Respiratory Distress protocol

    used to capture patients

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    Adult Respiratory Distress Protocol(Age greater than 12)

    Routine Medical Assessment

    Oxygen

    2 LPM via Nasal Cannula

    Titrate to maintain Pulse ox of >92%

    Is Patient a candidate for Mask CPAP?

    -Respiratory Rate > 25 / min

    -Retractions or accessory muscle use-Pulse ox < 94% at any time

    See Mask CPAP Protocol

    No

    Yes

    No

    No

    Is the Patient wheezing and/or does

    the Patient have a history of Asthma/COPD?

    Does the Patient have rales and/or does the

    Patient have a history of congestive heart

    failure (CHF)?

    YesAdminister Albuterol /

    Atrovent by Nebulizer

    If Basic IV Tech:

    Administer 1 spray

    sublingual NTG every

    5 minutes as long as

    systolic BP is greater than

    100mmHg

    Yes

    Contact Medical Control

    Consider ALS Intercept and Transport

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    Asses Patient, record vital signs

    and pulse ox before applying oxygen

    Does the Patient meet two or more

    Inclusion Criteria?No

    Yes

    Does the Patient meet any

    Exclusion Criteria?

    Continue standard BLS

    Respiratory Distress Protocol

    Administer CPAP

    5 cm H2O of pressure AND

    Reassess patient, vital signs, and

    respiratory distress scale every 5 min.

    Notify Medical Control

    Consider ALS Intercept

    and continue BLS

    Respiratory Distress Protocol

    Patient condition is stable

    or improving

    Continue CPAP

    Reassess patient every

    5 minutes

    Patient condition is deteriorating

    Decreasing LOC

    Decreasing Pulse Ox

    Notify Medical Control

    Remove CPAP

    Apply BVM Ventilation

    Mask CPAP for EMT-Basic

    CPAP Inclusion Criteria

    (2 or more of the following)

    -Retractions or Accessory muscle use-Respiratory Rate > 25 / minutes

    -Pulse Ox < 94% at any time

    CPAP Exclusion Criteria

    -Unable to follow commands

    -Apnea

    -Vomiting or active GI bleed

    -Major trauma / pneumothorax

    Conditions Indicated for CPAP

    Congestive Heart Failure

    COPD / Asthma

    Pneumonia

    Yes

    No

    Complete CPAP Data Form and

    submit to service Medical Director

    for each patient placed on CPAP

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    Wisconsin EMT-Basic Experience

    Results (preliminary study completed11/05)

    500 applications of CPAP (114 services)

    99% met criteria for CPAP on review of medicaldirector

    No field intubations by those services with ALSintercepts

    No significant complications

    All oxygen sats. improved, dyspnea reduced byaverage of 50%

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    Wisconsin EMT Basic Experience

    State approved CPAP for EMT-Basic

    scope of practice 2/06

    Questions yet to be answered

    What conditions did the patients have?

    Was it applied too liberally?

    Key Point

    Services without ALS intercept did just as well

    as those with it

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    Eau Claire Fire Experience

    Paramedic service

    July 2003 June 2004

    Measured end-tidal CO2, oxygen sats.,and subjective dyspnea score

    COPD/Asthma Continuous nebs

    CHF Nitro infusion or repeated sprays

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    Eau Claire Fire Experience

    50 applications

    No field intubations

    Initial CO2 levels average 62All patients CO2 levels increased during

    first 5 minutes

    CO2 levels increasing more than 10positively predicted CPAP failure

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    Indications for CPAP

    CHF

    Pulmonary Edema

    Near Drowning

    Inhalation Exposure

    COPD

    AsthmaPneumonia

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    Items to Consider

    How good is current care for respiratory

    distress?

    Aggressive nitrates for CHF?

    Aggressive use of bronchodilators?

    Pre-hospital and hospital intubation rate?

    Requires active medical oversight

    Airway management is a sentinel event

    ALS or BLS or BOTH?

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    Items to Consider

    Equipment

    Must be easy to use and portable

    Adjustable to patients need

    Easily started and discontinued

    Provide quantifiable and reliable airway

    pressures

    Conservative oxygen utilization

    Not interfere with administration traditional

    therapies for underlying condition

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    Items to Consider

    Oxygen concentration

    Fixed versus Variable rates

    Fixed rates are either 35% or 100% in current

    models but actual concentration will be lessdepending on leaks and minute ventilation

    Variable rate increases chance of inadequate

    oxygen supply

    Pressure levelMost studies show 5cm H20 sufficient

    Complication rate goes up with pressure

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    Summary

    CPAP is a non-invasive procedure that is

    easily applied and can be easily

    discontinued without untoward patient

    discomfort

    CPAP is an established therapeutic

    modality

    Data supports its use in CHF, pulmonary

    edema, COPD/Asthma, and pneumonia

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    Questions?