curriculum vitae david b. keator, ph.d....• ying jow pai kung fu – black sash, instructor •...

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CURRICULUM VITAE David B. Keator, Ph.D. PERSONAL INFORMATION Associate Professional Researcher Department of Psychiatry & Human Behavior Operations Director Neuroscience Imaging Center School of Medicine Chief Information Officer BrainCircuits Lab Department of Neurology University of California, Irvine Neuroscience Imaging Center Irvine Hall Room 163 Irvine, CA 92697-3960 Tel: (949) 824-7870 Fax: (949) 824-2230 E-mail [email protected] URL http://faculty.sites.uci.edu/davidkeator/ EDUCATION Graduate 2008-2015 Ph.D. Computer Science – Department of Computer Science, University of California, Irvine Field of Study: Machine Learning Dissertation: Probabilistic Models for Brain Image Collection, Classification, and Functional Connectivity. Advisor: Alexander Ihler, Ph.D. 1997-01 M.S. Computer Science – Department of Electrical and Computer Engineering, California State University, Long Beach Field of Study: Software Engineering Undergraduate 1990-94 B.S. Biological Science – Department of Biological

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  • CURRICULUM VITAE David B. Keator, Ph.D.

    PERSONAL INFORMATION Associate Professional Researcher Department of Psychiatry & Human Behavior Operations Director Neuroscience Imaging Center School of Medicine Chief Information Officer BrainCircuits Lab Department of Neurology University of California, Irvine Neuroscience Imaging Center Irvine Hall Room 163 Irvine, CA 92697-3960 Tel: (949) 824-7870 Fax: (949) 824-2230 E-mail [email protected] URL http://faculty.sites.uci.edu/davidkeator/ EDUCATION Graduate 2008-2015 Ph.D. Computer Science – Department of Computer Science, University of California, Irvine Field of Study: Machine Learning

    Dissertation: Probabilistic Models for Brain Image Collection, Classification, and Functional Connectivity. Advisor: Alexander Ihler, Ph.D.

    1997-01 M.S. Computer Science – Department of Electrical and Computer Engineering, California State University, Long Beach Field of Study: Software Engineering Undergraduate 1990-94 B.S. Biological Science – Department of Biological

  • Sciences, University of California, Irvine Language(s) English ACADEMIC APPOINTMENTS 2016 - Present Associate Professional Researcher Department of Psychiatry and Human Behavior Operations Director - Neuroscience Imaging Center School of Medicine University of California, Irvine 2002 – 2016 Specialist, University of California, Irvine Director of Scientific Computing Operations Director - Neuroscience Imaging Center Department of Psychiatry and Human Behavior NON-ACADEMIC APPOINTMENTS 1997 – Present President/Founder, Brain Imaging Legal Services 1996 – 2002 Programmer/Analyst II, University of California, Irvine

    Department of Psychiatry and Human Behavior 1994 – 1996 Staff Research Asst. I, University of California, Irvine Department of Psychiatry and Human Behavior 1990 – 1994 EEG Technician, University of California, Irvine

    Department of Psychiatry and Human Behavior AWARDS AND HONORS

    • Graduate Dean’s List Award – CSULB Department of Engineering and Computer Science

    • Phi Kappa Phi National Honor Society • Ying Jow Pai Kung Fu – Black sash, Instructor • National Eagle Scout Association • Assistant Cubmaster, Pack 688, Rancho Santa Margarita, CA. (2012-2013) • Assistant Scoutmaster, Troop 727, Rancho Santa Margarita, CA. (2014-present)

    PROFESSIONAL ACTIVITY

    • INCF Neuroinformatics channel Advisory Board • Review Editor - Frontiers in Brain Imaging Methods • Reviewer – IEEE Transactions on Computational Biology and Bioinformatics • Reviewer – IEEE Transactions on Information Technology in Biomedicine • Reviewer – IEEE Transactions on Medical Imaging • Reviewer – IEEE Visualization • Reviewer – Computer Methods and Programs in Biomedicine • Reviewer – NeuroImage

  • • Reviewer – PLoS ONE MEMBERSHIP IN PROFESSIONAL ORGANIZATIONS

    • IEEE • IEEE Computer Society

    INVITED PRESENTATIONS

    • “Using the neuroimaging data model (NIDM) for databasing and querying complex data”, Neuroscience 2016, The 39th Annual Meeting of the Japan Neuroscience Society, Yokohama Japan, July 20-22, 2016.

    • “Standardizing Metadata in Brain Imaging”, NeuroInformatics 2015, Cairnes, Australia, August 20-22, 2015.

    • Keynote: “Sharing Semantically Meaningful Neuroimaging Provenance and

    Derived Data using the Neuroimaging Data Model (NIDM)”, Advances in Neuroinformatics, Tokyo, Japan, September 25-26, 2014.

    • “Design and application of a biologically inspired feature model, a

    Bayesian mixture of experts model, and a topic model to functional brain imaging.”, Neural Information Processing (NIPS) Workshop on Machine Learning and Interpretation in Neuroimaging, Sierra Nevada, Spain, December 16-17, 2011.

    • “Function Biomedical Informatics Research Network”, GlobusWorld, Chicago,

    IL, March 2-4, 2010.

    • “Alzheimer’s Disease Classification using Positron Emission Tomography (PET) and Feature Selection Inspired by Visual Cortex”, UC Irvine Information and Computer Science eHealth Workshop, Irvine, CA. 2009.

    • “Functional Biomedical Informatics Research Network (FBIRN)”, UK E-Science

    Workshop, Edinburgh Scotland, October 2-3, 2006.

    TEACHING July 23-25, 2016 INCF Japan Node / NIDM Hackathon NIDM Workshop August 17-18, 2015 Neuroinformatics 2015 NIDM Workshop Cairnes, Australia Spring 2012 INF 171/ Public Health 119 Medical Informatics University of California, Irvine Guest Lecturer: Medical Imaging Informatics

  • Winter 2011 INF 171 Medical Informatics University of California, Irvine Guest Lecturer: Introduction to Medical Imaging Winter 2009 INF 171 Medical Informatics University of California, Irvine Guest Lecturer: Introduction to Medical Imaging RESEARCH CURRENT RESEARCH 1P41EB019936-01A1(PI: Kennedy) 2016-2021 WA00433491 (Potkin/Keator) Center for Reproducible Neuroimaging Computation (CRNC) The Center for Reproducible Neuroimaging Computation (CRNC), a Biomedical Technology Research Center, is dedicated to establishing and promoting reproducible neuroimaging research through the use of semantic web and software container technologies. 1P50MH096889-01A1 (PI: Baram) 2013 –2018 Fragmented Early Life Environmental and Emotional / Cognitive Vulnerabilities Environmental and Biological Variation Role: Informatics Core Director The major goals of this project are to probe the effects of fragmented early life experience on neuronal network structure and function using magnetic resonance brain imaging (MRI) of rats and humans. Responsible for the development of a center-wide, cross-species informatics platform. 1U01AGO51412-01 (PI: Lott) 2015-2020 Columbia Univ/NIH Biomarkers of Alzheimer's Disease in Down Syndrome Role: Data Analysis Goals: The overall aim of this project is to identify biomarkers associated with the progression of Alzheimer’s disease (AD) from its prodromal stages to frank dementia in adults with Down syndrome (DS), responding to RFA-AG-15-011. Adults with DS are at high risk for AD. However there is a wide range of age at onset and a substantial proportion of adults with DS maintain their abilities even at older ages associated with extensive neuropathology. The objective of this project is to identify the factors contributing to these individual differences through a longitudinal analysis of biomarkers of dementia status. 1U01MH097435-01A1 (PI: Potkin) 2013-2016 UCI Award : 60033871 (POTKIN) $335,942 Northwestern University (Prime NIH)

  • SchizConnect: Large-Scale Schizophrenia Neuroimaging Data Mediation and Federation Role: Co-Investigator The major goals are to develop SchizConnect Mediator, an algorithmic approach to querying and integrating information from disparate, heterogeneous databases, to enable data retrieval easily and precisely. To establish and validate a web-based portal, SchizConnect, which will provide a uniform, structured, and user-friendly interface to query and download data provided by the Mediator. Responsible for UCI contribution to the SchizConnect resource and integration of NIDM semantic neuroimaging metadata format. PENDING RESEARCH – Under Review 1 R24 ES028512-01 (PI Keator / Turner) 2017-2020 NIH $1,190,459 Document, Link, and Reuse: Standardizing Experiment Metadata in Neuroscience Role: Principle Investigator Reuse of existing neuroscience data relies, in part, on our ability to understand the experimental design and study data. Our vision is to build on existing resources to create annotation and discovery tools that are based on a metadata standard expressive enough to provide unambiguous descriptions of the experimental methods and metadata. In this proposal, we develop the Experiment Data Model (EDM), a metadata format leveraging techniques from the semantic web, capable of precisely describing information about the design and intent of an experiment, experimental subject characteristics, and the acquired data. The deliverables in this proposal will create an information architecture of a "Data Commons" to achieve Findable, Accessible, Interoperable, and Reusable metadata. The Aims consist of three interleaved components: (1) Develop EDM conceptual metadata models through community engagement and multi-species partner projects in schizophrenia, adolescent cognitive development, and post-traumatic stress disorder; (2) Develop use-case driven software tools for EDM document creation and annotation; (3) Foster adoption through comprehensive training materials and community workshops for users and developers. Project Seed Funding 2017-2018 International Neuroinformatics Coordinating Facility (INCF) $20,000 Integrating NIDM-Experiment and the Brain Imaging Data Structure Role: Principle Investigator Acceleration of scientific discovery relies on our ability to effectively use data often acquired across multiple domains. Typically, subsets of data collections are shared using lab-specific organizational schemes with little or no information provided to give the data context within the broader experimental protocol nor the ability to efficiently use the data for reproducibility outside of the originating site. To address these challenges, the INCF supported two related efforts. The Neuroimaging Data Model (NIDM; http://nidm.nidash.org/) was developed to provide a linked data format for describing all aspects of the data lifecycle, from raw data through analyses and provenance. The NIDM-Experiment component describes the experiment metadata, giving the acquired data context within the broader project protocol. The Brain Imaging Data Structure

  • (BIDs; http://bids.neuroimaging.io/) was designed to provide software developers and the neuroimaging community with a standard for organizing the data collected in an imaging experiment to more easily automate analysis workflows. In this project we develop converters to both export imaging datasets described in NIDM-Experiment documents as BIDs-formatted data sets, providing access to BIDs supported workflows, and import of BIDs data sets to NIDM-Experiment documents, facilitating sharing and linking of BIDs data sets outside of the originating laboratory and contextualizing BIDs data sets with respect to the experiment protocols. COMPLETED RESEARCH 1U01NS087825-01 (PI: Potkin) 2014-2016 NIH/NINDS $250,000 CSF-enhanced-aggregation Biomarker for Huntington’s Disease Role: Neuroimaging Analysis Huntington’s disease is a progressive and fatal illness with no known treatment. This proposal refines a CSF biomarker measure to diagnose and monitor the progression of HD. The availability of such a biomarker is crucial to the efficient development of novel treatments for HD. Responsible for UCI structural neuroimaging data analysis. U24 RR025736-01 (PI Kesselman) 2008 –2013 UCI Award : 150266 (PI Potkin) $486,277 Univ of Southern CA (Prime NCRR/NIH) Bio-Informatics Research Network Coordinating Center (BIRN-CC) Role: Co-Investigator The purpose of this grant is to maintain, support, and enhance the software tools developed under the BIRN testbed grants (Function BIRN led by Dr. Steven Potkin at the University of California, Irvine (U24RR21992, end date November 30, 2010); Morphometry BIRN led by Dr. Bruce Rosen at Massachusetts General Hospital (U24RR21382, end date May 31, 2009), and Mouse BIRN led by Dr. Arthur Toga at the University of California, Los Angeles. (U24RR21760, end date April 30, 2010)) for the analysis of neuroscience and neuroimaging data and extend those tools to support similar workflows for domains outside neuroscience. Responsible for UCI’s contribution of FBIRN tools and data. U24 RR026057 (PI Rosen) UCI Award : 215287 (PI Potkin) 2009-2013 MA General Hospital $298,589 Role: Co-Investigator Collaborative Tools Support Network (CTSN) The major goals of this project are to provide expertise in multi-center imaging data collection, management, and analysis; and to facilitate the transfer of multi-center imaging tools and methods to the Collaborate Tools Support Network. Responsible for

  • outreach to investigators interested in using FBIRN tools and data within the collaborative tools network. 5 U24 RR21992 (PI Potkin) 2009 –2013 NCRR/NIH $20,651,999 Function BIRN Role: Co-Investigator, Neuroinformatics Chair The BIRN is an NCRR initiate aimed at creating a testbed to address biomedical researchers’ need to access and analyze data at a variety of levels of aggregation located at diverse sites throughout the country. The BIRN testbed will bring together hardware and develop software necessary for a scalable network of databases and computational resources. The FIRST BIRN is dedicated to the development of multi-site functional imaging studies and databases, applied initially to the problem of schizophrenia. Chair of the neuroinformatics working group of FBIRN. Responsible for multi-site tools and data sharing methods. HHSN271200800006C (Wigal) 2010 –2012 PHS-NIH $1,299,836 Role: UCI Informatics Director The MTA study neuroimaging add on study plans to address the underlying neurophysiological mechanisms that have been theorized to place individuals with a diagnosis of ADHD at increased risk for a range of Substance Usage Disorder (SUDs). Responsible for publically available MTA data set. Alzheimer's Disease Neuroimaging Initiative (PI Weiner) 2005-2009 UCI Award: $1,110,975 (PI Potkin) UCSD- NIH Role: PET Acquisition and Data Analysis Longitudinal identification of brain imaging measures (sMRI, FDG PET, amyloid PET) of AD and MCI (mild cognitive impairment). PUBLICATIONS Abstracts and Conference Proceedings

    1. Potkin, S. G., Wu J., Fallon F., Anand R., Hartman R., Bera R., Carreon D., Telford J., Plon L., Keator D.B. "S-28-6 Functional neuroimaging to evaluate atypical antipsychotic compounds: an FDG PET study of SDZ MAR 327." European Neuropsychopharmacology 5, no. 3 (1995): 241-242.

    2. Wu, J. C., Klein E.A., Bell K. M., Widmark C. B., Keator D.B. "Reduced limbic FDG metabolism in cocaine addicts is left-lateralized and normalizes after one month." Neuroimage 3, no. 3 (1996): S523.

  • 3. Bell K. M., Klein E.A., Wu J.C., Widmark C.B., Najafi A., Keator D.B. "360.-A PET study of PET FDOPA uptake in abstaining cocaine addicts." Biological Psychiatry 39, no. 7 (1996): 606.

    4. Potkin, S., Wu J., Anand R., Bera R., Carreon D., Hartman R., Keator D.B.. "S-2-3-Neuroimaging to evaluate atypical antipsychotic compounds: An FDG pet study of SDZ MAR 327." European Neuropsychopharmacology (1996):6, 17-18.

    5. Potkin SG, Kennedy J, Badri F, Jin Y, Masellis M, Gulasekaram B, Costa J, Keator DB, Telford J, Wu JC, Najafi A: “D1 Alleles Predict Clinical Response to Clozapine and Corresponding Brain Metabolism: A Genetic PET Scan Study,” International Congress on Schizophrenia Research, 1997.

    6. Potkin SG, Jin Y, Bunney B, Gulasekaram B, Costa J, Keator DB, Telford J, Wu JC, Najafi A, Bunney WE Jr.: “Clinical and Brain Imaging Effects of Adjunctive High Dose Glycine with Clozapine in Schizophrenia,” International Congress on Schizophrenia Research, 1997.

    7. Potkin SG, Arnand R, Messina J, Hartman R, Keator D, Wu JC, Maguire G, Fleming K, Dockstader T: FDG PET: A Sensitive and Quantitative Tool To Measure Progression of Alzheimer’s Disease And Brain Metabolic Effects of Rivastigmine Tartrate –poster presented at the American Academy of Neurology, Minneapolis, MN, April 30, 1998.

    8. Potkin SG, Bera R, Keator D, Fleming K, Alva G, Carreon D, Kranz L:“Distinguishing Predominantly Negative Symptom Schizophrenia with FDG PET.” Poster presented at the International Congress on Schizophrenia Research, Santa Fe, NM, April 17-21, 1999.

    9. Potkin SG, Basile VS, Badri F, Keator D, Wu JC, Alva G, Doo M, Bunney WE Jr., Kennedy JL: “D1 Receptor Alleles Predict PET Metabolic Correlates of Clinical Response to Clozapine.” Abstract published in The International Journal of Neuropsychopharmacology, 3(Suppl 1):S6, 2000.

    10. Potkin SG, Shipley J, Bera RB, Carreon D, Fallon J, Alva G, Keator D. “Clinical and PET Effects of M100907, A Selective 5HT-2A Receptor Antagonist”, abstract published in Schizophrenia Research, 49(1-2 Supplement):242.

    11. Potkin, SG, Anand, R, Alva, G, Fleming, K, Keator, D, Carreon, D, Messina J, Wu, JC, Hartman, R, Fallon, JH: FDG PET and Clinical Effects in Placebo and Rivastigmine Treated Subjects with Alzheimer’s Disease, International Congress of Geriatric Psychiatry, December 14-15, 2001, Waikola, Hawaii.

  • 12. Keator, D: Medical Image Normalization and Surface Reconstruction Techniques, Youth Leadership Forum, July 10 & 24, 2002, University of California, Irvine.

    13. Potkin SG, Keator DB, Mbgori J, Fallon JH, UC Irvine TTURC: “Brain Metabolic Effects of Nicotine Patch in High and Low Hostility Subjects,” Society for Research on Nicotine & Tobacco, 2003.

    14. Fallon JH, Keator DB, Mbgori J, Potkin SG, UC Irvine TTURC: “Gender and Ethnic Differences in Brain Metabolism Following Nicotine Patch,” Society for Research on Nicotine & Tobacco, 2003.

    15. Turner, J.A.; Potkin, S.G.; Brown, G.G.; Glover, G.H.; Greve, D.; Keator, D.B.; McCarthy, G.; Grethe, J.S.; Wible, C.G.; Lim, K.; Toga, A.W.; Andreasen, N.C.; O’Leary, D.; FIRST BIRN. Biomedical Informatics Research Network: Integrating Multi-Site Human Functional Imaging Acquisition and Analysis. Poster presented at the NIH Biomedical Information Science and Technology Initiative Consortium (BISTIC), 2003.

    16. Potkin SG; Turner JA; Brown GG; Glover GH; Heckers S; Keator DB; Grethe JS. Biomedical Informatics Research Network: Functional Imaging Research in Schizophrenia Test Bed. Poster presented at Neuroscience, 2003.

    17. Kemp, A.S., Aulakh, J., Jin, Y., Huerta, S.T., Keator, D.B., O’Halloran, J.P., Potkin, S.G.. Fronto-Parietal EEG Coherence Correlates with Semantic Fluency and Cortical Glucose Metabolism in Patients with Alzheimer’s Disease. Society of Biological Psychiatry Annual Meeting, San Francisco, May 15-17, 2003.

    18. Turner, J.A.; Potkin, S.G.; Glover, G.; McCarthy, G.; Gollub, R.L.; Brown, G.; Dale, A.; Grethe, J.S.; Friedman, L.; Keator, D.B.; FIRST BIRN. Biomedical Informatics Research Network: Functional Imaging Research in Schizophrenia Testbed. Abstract and poster at Organization of Human Brain Mapping, 2004.

    19. Ozyurt, B.I.; Wei, D.; Keator, D.B.; Potkin, S.G.; Brown, G.; Grethe, J.; FIRST BIRN. A General and Extensible Database System for the Storage,

  • Retrieval and Maintenance of Human Brain Imaging and Clinical Data. Abstract and poster presentation at Organization of Human Brain Mapping, 2004.

    20. Ozyurt, B.I.; Wei, D.; Keator, D.B.; Potkin, S.G.; Brown, G.; Grethe, J.; Web-Accessible Clinical Data Management within an Extensible Neuroimaging Database. Abstract and poster presentation at Society for Neuroscience, 2004.

    21. Keator, D.B.; Gadde, S.; Grethe, J.S.; Taylor, D.V.; Potkin, S.G.; FIRST BIRN. A General XML Schema and Associated SPM Toolbox for Storage and Retrieval of Neuro-Imaging Results and Anatomical Labels. Abstract and poster presentation at Organization of Human Brain Mapping, 2004.

    22. Fleming, K; Keator, D.B.; Fallon, J; Mbogori, J; Potkin, S. High Impulsivity Non-Smokers have a Robust Brain Metabolic Response to Nicotine. Abstract and poster presentation at American College of Neuropsychopharmacology (ACNP) meeting, 2004.

    23. Keator, D.B.; Gadde, S.; Grethe, J.S.; Taylor, D.V.; Potkin, S.G.; FIRST BIRN. A General XML Schema and Associated SPM Toolbox for Storage and Retrieval of Neuro-Imaging Results and Anatomical Labels. Abstract and poster presentation at Human Brain Project Neuro-Informatics meeting, 2004.

    24. Keator, D.B.; Gadde, S.; Grethe, J.S.; FIRST BIRN. XML Schema and Methods for a Common Image Format. Presentation at the Neuroimaging Informatics Technology Initiative (NIfTI) Data Format Working Group Meeting, NIH 2004.

    25. Ozyurt, I. B., Wei D., Keator D.B., Potkin S.G., Brown G.G., Grethe J., B. I. R. N. Morphometry, and Coordinating Center BIRN. "A user-friendly, web-accessible system for the management, discovery, retrieval, and analysis of clinical and brain imaging data." Human Brain Project Neuro-Informatics meeting. 2004.

    26. Potkin, S. G., Alva G., McDonald S., Gergel I., Keator D.B., Fallon J.H.. "Memantine monotherapy increases brain metabolism and effectively treats mild to moderate Alzheimer's disease." Annals Of Neurology, 2004; vol. 56, pp. S48-S49.

    27. Potkin, S.G., Brown g.G., Glover G. H., McCarthy G., Lim K. O., Gollub R., Rosen, Toga A., Kikinis R., Dale A., Lauriello J., O'Leary D., Lieberman J., Belger A., Greve D., Friedman L., Cannon T., Fallon J., Keator D.B., Grethe J.S., Turner J.A.. "Functional biomedical informatics research network: Multi-center fMRI methods." Neuropsychopharmacology, vol. 29, pp. S221-S221.

  • 28. V. Sossi, H. W. A. M. de Jong, W. C. Barker, P. Bloomfield, Z. Burbar, M.-L. Camborde, R. E. Carson, C. Comtat, L. A. Eriksson, S. Houle, D. Keator, C. Knöß, R. Krais, A. A. Lammertsma, A. Rahmim, M. Sibomana, M. Teräs, C. J. Thompson1, R. Trébossen, J. Votaw, K. Wienhard, D. F. Wong. The second generation HRRT – a multi-centre scanner performance investigation. Abstract and poster presentation at IEEE Medical Imaging Conference, 2005.

    29. B.I. Ozyurt; D. Wei; D.B. Keator; J.H. Bockholt; K.R. Pease; H.E. Schmidt; FIRST BIRN; Morphometry BIRN; BIRN-CC; J.S. Grethe. Scientific Data Management With an Extensible Neuroscience Database. Abstract and poster presentation at Society for Neuroscience, 2005.

    30. Mukherjee J; Keator D; Collins D; Jackson H; Vivatpattanakul B; Pichika R; Christian B; Fallon J; Wu J. High Resolution HRRT-18F-Fallypride PET of the Human Brain. Abstract and poster (#652435) Radiological Society of North American Annual Meeting, 2005.

    31. Potkin S; Turner J; Brown G; Stern H; Glover G; McCarthy G; Greve D; Friedman L; Keator D; Grethe J; Fallon J; Lim K; Gollub R; Rosen B; Toga A; Kikinis R; Lauriello J; O’Leary D; Belger A; FBIRN. Multicenter fMRI Methods and Design: Function BIRN. Abstract and poster (100.18/PP35) presentation at Society for Neuroscience, 2006.

    32. Keator D; Ozyurt BI; Wei D; Gadde S; Potkin SG; Brown G; MBIRN; FBIRN; Grethe J. A General and Extensible Multi-Site Database and XML based Informatics System for the Storage, Retrieval, Transport, and Maintenance of Human Brain Imaging and Clinical Data. Abstract and poster (253 TH-AM) presentation at Organization of Human Brain Mapping, 2006.

    33. Keator D; Grethe J; Ozyurt B; Gadde S; Wei D; Turner J; Potkin S; Brown G; McCarthy G; Glover G; Stern H; Lauriello J; Friedman L; Belger A; Lim K; Pieper S; Greve D; FBIRN. Function Biomedical Imformatics Research Network (FBIRN) Open Source FMRI Informatics, Calibration, and Data Tools Repository. Abstract and poster (252 TH-PM) presentation at Organization of Human Brain Mapping, 2006.

  • 34. Turner, J.; Potkin, S. G.; Brown, G. G.; Stern, H. S; Glover, G. H.; McCarthy, G.; Greve, D. N.; Friedman, L.; Keator, D.; Grethe, J. S. Fallon, J. H.; Lim, K. O.; Gollub, R. L.; Rosen, B. R.; Toga, A. W.; Kikinis, R.; Pieper, S.; Lauriello, J.; O'Leary, D. S.; Belger, A.; Function BIRN. Multi-center fMRI methods and design: Function BIRN. Annual Meeting of the Society for Neuroscience, Atlanta, GA. 2006.

    35. Ford, J; Mathalon, D; Roach, B; Turner, J; Potkin, S; Brown, G; Wible, C; McCarthy, G; Greve, D; Mueller, B; Keator, D; Lim, K; O’Leary, D; Belger, A; Voyvodic, J; Glover, G; Lauriello, J; FBIRN. (2007). Hallucinations and deviant tones compete for primary auditory cortical resources: Multi-site fMRI study of schizophrenia. Annual Meeting of the Society for Neuroscience, San Diego, CA. 2007.

    36. Lee K.; Hong I; Potkin S.; Burbar Z.; Keator D. High Resolution PET Listmode Motion Correction Using 3D Motion Data. Abstract and poster presentation at Joint Molecular Imaging Conference, 2007.

    37. Lee, K.; Potkin, S.; Keator, D.; Hong, I. Fast 3-D Motion Correction using the Characteristics of Motion in Rigid Body. Abastract and poster presentation at IEEE Medical Imaging Conference, Dresden, Germany, 2008 .

    38. Potkin, S., Turner, J., Fallon, J., Lakatos, A., Keator, D., Guffanti, G., Macciardi, F., FBIRN. Gene Discovery Through Imaging Genetics: Identification of Two Novel Genes Associated with Schizophrenia. Abstract and poster presentation at International Conference on Schizophrenia Research, 2009.

    39. Abe, S., Preda, A., Turner, J., Keator, D., Potkin, S., FBIRN. DTI Co-registration Method Comparison Based on DTI Tractography Analysis in the Human Brain. Abstract and poster presentation at Organization of Human Brain Mapping, San Francisco, CA., 2009.

    40. Potkin, S., Keator D., Mukherjee J., Preda A., Highum D., Gage A., Xie J., Ghahramani P., Laszlovsky I. "P. 1. e. 028 Dopamine D3 and D2 receptor occupancy of cariprazine in schizophrenic patients." European Neuropsychopharmacology 2009; 19: S316.

  • 41. Mathalon, Daniel H., Kasper W. Jorgensen, Brian J. Roach, Vince D. Calhoun, Michele T. Diaz, Gregory G. Brown, Randy Notestine Amanda Bischoff-Grethe, Doug Greve, Gregory McCarthy, Aysenil Belger, Jessica A Turner, Steven G Potkin, Cindy G Wible, Bryon A Mueller, John Lauriello, Gary H Glover, Kelvin O Lim, Daniel S O'Leary, Adian Preda, David Keator, Theo Van Erp, Judith M Ford. "Failure of Normal Aging-Related Hemispheric Asymmetry Reduction in Brain Activity During Target Detection in Schizophrenia." Biological Psychiatry, 2010; vol. 67, no. 9, pp. 252S-252S.

    42. Keator, D.B., Fowlkes, C., Fallon, J., Potkin, S., Ihler, A. Alzheimer’s Disease Classification using PET and Oriented Hierarchical Filtering. Abstract and poster presentation at Organization of Human Brain Mapping, Barcelona, Spain. 2010.

    43. Bunney, W., Keator, D., Potkin, S., Fallon, J., Preda, A., Mukherjee, J., Nguyen, D., Kesler-West, M., Shah, N. Ziprasidone D2 Receptor Occupancy at Doses of 120 to 240mg/day Measured with 18F-Fallypride PET Support Once-A-Day Dosing. ACNP 49th Annual Meeting, Miami Beach, FL. 2010.

    44. Keator D.B., Chen J., Ashish N., Torri F.,Lakatos A., Potkin S.G., Macciardi F., Wei D. HID-Genetics: A Federated BIRN-enabled Data Management System for Clinical, Imaging, and Genome-Wide Association Studies. Abstract and poster presentation at Neuroinformatics Congress 2011, Boston, MA. 2011.

    45. Van Erp T.G.M, Chervenak A., Kesseman C., D’Arcy M., Sobell J., Keator D.B., Dahm L., Murry J., Law M., Hasso A., Ames J., Macciardi F., Potkin S. Infrastructure for Sharing Standardized Clinical Brain Scans Across Hospitals. Paper and poster presentation at IEEE International Conference on Bioinformatics and Biomedicine, Atlanta, GA. 2011.

    46. Lakatos, Anita, Jerod Rasmussen, Theo Van Erp, Frijthof Kruggel, David Keator, and Steven Potkin. "Hippocampal metabolism deficit in elderly with mild cognitive impairment." Alzheimer's & Dementia 7, no. 4 (2011): S321-S322.

    47. Potkin S.G., Preda A., Nguyen D., Keator D., van Erp T.G.M., Kemp A., Fallon F. A brain imaging and neurocognitive study of subjects treated with aripiprazole. Abstract and poster presentation at Psych Congress, San Diego, CA 2012.

    48. Helmer K., Ghosh S., N ichols N.B., Keator D., Nichols T., Turner J. Connecting Brain Imaging Terms to Established Lexicons: a Precursor for Data

  • Sharing and Querying. Abstract and poster presentation at Neuro-Informatics Congress. Munich, Germany 2012.

    49. Ghosh S., Nichols N.B., Gadde S., Steffener J., Keator D. XCEDE-DM: A neuroimaging extension to the W3C provenance data model. Abstract and poster presentation at Neuro-Informatics Congress. Munich, Germany 2012.

    50. Potkin S.G., Preda A., Nguyen D., Keator D.B., Keslerwest M., Van Erp T.G.M., Kemp A., Fallon J. A Brain Imaging and Neurocognitive Study of Schizophrenic Subjects Treated with Aripiprazole. Abstract and poster presentation at U.S. Psychiatric and Mental Health Congress. San Deigo, CA 2012.

    51. Nichols N., Stoner R., Keator D.B., Turner J., Helmer K.G., Ashish N., Steffener J., Grabowski T.J., Ghosh S. There’s an app for that: a semantic data provenance framework for reproducible brain imaging. Abstract and poster presentation at Organization of Human Brain Mapping, Seattle, WA. 2013.

    52. Nichols N., Steffener J., Haselgrove C., Keator D.B., Stoner R., Poline J.B., Ghosh S. Mapping Neuroimaging Resources into the NIDASH Data Model for Federated Information Retrieval. Abstract and poster presentation at Neuroinformatics 2013, Stockholm, Sweden. 2013.

    53. K.G. Helmer, S. Ghosh, D. Keator, C. Maumet, B.N. Nichols, T. Nichols, J.B. Poline, J. Steffener, J. Turner, W. Wong, M. Martone. The Addition of Neuroimaging Acquisition, Processing and Analysis Terms to Neurolex. Submitted abstract to Organization of Human Brain Mapping, Hamburg, Germany. 2014.

    54. Helmer, K., S. Ghosh, B. Nichols, D. Keator, T. Nichols, and J. Turner. "Connecting Brain Imaging Terms to Established Lexicons: a Precursor for Data Sharing and Querying." In Front. Neuroinform. Conference Abstract: 5th INCF Congress of Neuroinformatics. doi: 10.3389/conf. fninf, vol. 65. 2014.

    55. C. Maumet, T. Nichols, B.N. Nichols, G. Flandin, J. Turner, K.G. Helmer,J. Steffener, J.B. Poline, S. Ghosh, D. Keator. Extending NI-DM to share the results and provenance of a neuroimaging study: an example with SPM. Submitted abstract to Organization of Human Brain Mapping, Hamburg, Germany. 2014.

    56. D. Keator, S. Ghosh, C. Maumet., G. Flandin, B.N. Nichols, T. Nichols, G. Burns, R. Bruehl, C. Craddock, B. Frederick, K.J. Gorgolewski,

  • Y.O. Halchenko, M. Hanke, C. Haselgrove, K.G. Helmer, A. Klein, D. Marcus, M. Milham, F. Michel, R. Poldrack, J. Steffener, Y. Schwartz, R. Stoner, J. Turner, D. Kennedy, J.B. Poline. Developing and using the Neuroimaging and Data Sharing Data Model: the NIDASH Working Group. Abstract and Poster at Organization of Human Brain Mapping, Hamburg, Germany. 2014.

    57. Wang L, Alpert KI, Calhoun V, Keator D, King M, Kogan A, Landis D, Tallis M, Potkin SG, Turner JA, Ambite JL. SchizConnect: Large-Scale Schizophrenia Neuroimaging Data Integration and Sharing. Annual Meeting of the American College of Neuropsychopharmacology (ACNP); December, 2011; Phoenix, Arizona, 2014.

    58. Calhoun, Vince, Dan Mathalon, Theo van Erp, Sarah J. McEwen, Adrian Preda, Judy Ford, Elena Allen, Steven Potkin, Keator D.B., and Eswar Damaraju. "Dynamics Of Intrinsic Connectivity Networks In Schizophrenia." Schizophrenia Research 153 (2014): S12-S13.

    59. Helmer K.G.,Turner J. A., Maumet C., Nichols T., Nichols B.N., Keator D.B., Ghosh S., Auer T., Poline J.B. Developing Terminologies for the INCF Neuroimaging Data Model (NIDM). Abstract and Poster at Organization of Human Brain Mapping, Honolulu, Hawaii. 2015.

    60. Poline J.B., Keator D.B., Gorgolewski K.J., Auer T., Craddock C., Flandin G., Ghosh S., Halchenko Y., Hanke M., Haselgrove C., Helmer K., Jenkinson M., Klein A., Lanyon L., Marcus D., Margulies M., Maumet C., Michel F., Nichols B.N., Nichols T., Poldrack R., Reynolds R., Saad Z., Schmah T., Steffener J., Turner J., Van Erp T., Van Horn J.D., Das S., Kennedy D. How to make brain imaging research efficient and reproducible: building software and standards. Abstract and Poster at Organization of Human Brain Mapping, Honolulu, Hawaii. 2015.

    61. Nichols B.N., Keator D.B., Ghosh S., Maumet C., Flandin G., Nichols T., Gorgolewski K.J., Halchenko Y.O., Hanke M., Haselgrove C., Helmer K.G., Marcus D., Poldrack R., Turner J., Kennedy D., Poline J.B., Pohl K. M. Application of the Neuroimaging Data Model to Represent and Exchange Primary and Derived Data. Abstract and Poster at Organization of Human Brain Mapping, Honolulu, Hawaii. 2015.

    62. Maumet C., Nichols B.N., Flandin G., Helmer K.G., Auer T., Reynolds R., Saad Z., Chen G., Jenkinson M., Webster M., Steffener J., Gorgolewski K.J., Turner J., Nichols T., Ghosh S., Poline J.B., Keator D.B.

  • Standardized reporting of neuroimaging results with NIDM in SPM, FSL and AFNI. Abstract and Poster at Organization of Human Brain Mapping, Honolulu, Hawaii. 2015.

    63. Keator D.B., Poline J.B., Gorgolewski K.J., Auer T., Craddock C., Flandin G., Ghosh S., Halchenko Y., Hanke M., Haselgrove C., Helmer K., Jenkinson M., Klein A., Lanyon L., Marcus D., Margulies M., Maumet C., Michel F., Nichols B.N., Nichols T., Poldrack R., Reynolds R., Saad Z., Schmah T., Steffener J., Turner J., Van Erp T., Van Horn J.D., Das S., Kennedy D. Standardizing Metadata in Brain Imaging. Abstract and Oral Presentation at Neuroinformatics Congress, Cairnes Australia, 2015.

    64. Keator D.B., Chen J., Nichols N., Fana F., Small S.L. A Semantic Cross-Species Derived Data Management Application Powered by NIDM. Abstract and Poster at Organization of Human Brain Mapping, Geneva, Switzerland. 2016.

    65. Keator D.B., Dornan E., Yassa M, Lott I. Baseline [18F] AV-45 PET Predictors of Dementia Transition in Down Syndrome. Abstract accepted to The 13th International Conference on Alzheimer's & Parkinson's, Vienna, Austria 2017.

    Journal Articles, Peer Reviewed

    66. Potkin S.G.; Wu J.; Fallon F.; Bera R.; Carreon D.; Telford J.; Plon L.; Keator D.; Anand R.; Hartman R. Functional neuroimaging to evaluate atypical antipsychotic compounds: an FDG PET study of SDZ MAR 327. FEBS Letters. 1995 Sep; 5(3);241-242.

    67. Cahill L; Haier RJ; Fallon J; Alkire MT; Tang C; Keator D; Wu J; McGaugh JL. Amygdala activity at encoding correlated with long-term, free recall of emotional information. Proceedings of the National Academy of Sciences of the United States of America, 1996; 93(15):8016-21.

    68. Wu JC; Maguire G; Riley G; Lee A; Keator D; Tang C; Fallon J; Najafi A. Increased dopamine activity associated with stuttering. Neuroreport. 1997 Feb 10;8(3):767-70.

    69. Wu JC; Bell K; Najafi A; Widmark C; Keator D; Tang C; Klein E; Bunney BG; Fallon J; Bunney WE. Decreasing striatal 6-FDOPA uptake with increasing duration of cocaine withdrawal. Neuropsychopharmacology, 1997; 17(6):402-9.

  • 70. Wu, J; Buchsbaum MS; Gillin JC; Tang C; Cadwell S; Wiegand M; Najafi A; Hazen K; Keator D; Bunny WE Jr; et al. Prediction of antidepressant effects of sleep deprivation by metabolic rates in the ventral anterior cingulated and medial prefrontal cortex. American Journal of Psychiatry, 1999; 156(8): 1149-58.

    71. Wu J; Iacono R; Ayman M; Salmon E; Lin S; Carlson J; Keator D; Lee A; Najafi A; Fallon J. Correlation of intellectual impairment in Parkinson’s disease with FDG PET scan. Neuroreport, 2000; 11(10):2139-44.

    72. Potkin S; Anand R; Fleming K; Alva G; Keator D; Carreon D; Messina J; Hartman R; Fallon J. Brain Metabolic and clinical effects of rivastigmine in Alzheimer’s disease. International Journal of Neuropsychopharmacology, 2001; 4: 223-230.

    73. Potkin S; Alva G; Fleming K; Anand R; Keator D; Carreon D; Doo M; Jin Y; Wu J; Fallon J. A PET study of Pathophysiology of Negative Symptoms in Schizophrenia. American Journal of Psychiatry, 2002; 159(2):1-11.

    74. Potkin S; Alva G; Keator D; Carreon D; Fleming K; Fallon J. Brain metabolic effects of Neotrofin in patients with Alzheimer’s disease. Brain Research, 2002; 951:87-95.

    75. Potkin S; Basile V; Jin Y; Masellis M; Badri F; Keator D; Wu J; Alva G; Carreon D; Bunney W; Fallon J; Kennedy J. D1 receptor alleles predict PET metabolic correlates clinical response to clozapine. Molecular Psychiatry, 2003; 8:109-113.

    76. Fallon J; Keator D; Mbogori J; Turner J; Potkin S. Hostility differentiates the brain metabolic effects of nicotine. Cognitive Brain Research, 2004; 18(2):142-148.

    77. Fallon J; Keator D; Mbogori J; Taylor D; Potkin S. Gender: a major determinant of brain response to nicotine. International Journal of Neuropsychopharmacology, 2004; 8:1-10.

    78. Potkin S.G., McDonald S., Gergel I., Alva G., Keator D.B., Fallon J.H.. "P3-102 Memantine monotherapy increases brain metabolism (PET) and effectively treats mild to moderate Alzheimer's disease." Neurobiology of Aging, 2004: 25, S384.

  • 79. Potkin, S. G., McDonald S., Gergel I., Alva G., Keator D.B., and J. H. Fallon. "Memantine monotherapy increases brain metabolism (PET) and effectively treats mild to moderate Alzheimer's disease." International Journal of Neuropsycopharmacology, 2004.; vol. 7, pp. S380-S381.

    80. Turner, J., Potkin S.G., Brown G.G., Glover G.H., Fallon J.H., McCarthy G., Lim K.O., Gollub R.L., Rosen B.R., Toga A.W., Kikinis R., Pieper S., Dale A.M., Lauriello J., O'Leary D.S., Lieberman J.A., Belger A., Greve D.N., Friedman J., Cannon T.D., Keator D.B., Grethe J.S.. "Multi-center fMRI methods and design: function BIRN." Schizophrenia Bulletin, 2005; vol. 31, no. 2, pp. 437-438.

    81. Wu J; Gillin JC; Buchsbaum M; Chen P; Keator D; Khosla N; Darnall L; Fallon J; Bunney W. Frontal lobe metabolic decreases with sleep deprivation not total reversed by recovery sleep. Neuropsychopharmacology, 2006; 31(12):2783-92.

    82. Keator, D; Gadde, S; Grethe, J ; Taylor, D; FIRST BIRN; Potkin, S. A General XML Schema and Associated SPM Toolbox for Storage and Retrieval of Neuro-Imaging Results and Anatomical Labels. Neuroinformatics, 2006; 4(2):199-212.

    83. Potkin, S. G., Macciardi F., Friedman L., Turner J.A., Fallon J., Bunney W., Keator D.B.. "Imaging genetics model for the study of neuropsychiatric diseases." American Journal Of Medical Genetics Part B-Neuropsychiatric Genetics, 2006; vol. 141, no. 7, pp. 687-687.

    84. Wu J; Gillin C; Buchsbaum B; Schachat C; Darnall L; Keator D; Fallon J; Bunney W. Sleep deprivation PET correlations of Hamilton symptom improvement ratings with changes in relative glucose metabolism in patients with depression. Journal of Affective Disorders, 107, no. 1 (2008): 181-186.

    85. Keator, D.; Grethe, J.S.; Marcus, D.; Ozyurt, B.; Gadde, S.; Murphy, S.; Pieper, S.; Greve, D.; Notestine, R.; Bockholt, H.J; Papadopoulos, P.; Function BIRN; Morphometry BIRN; BIRNCoordinating Center. A National Human Neuroimaging Collaboratory Enabled By The Biomedical Informatics Research Network (BIRN). IEEE Transactions on Information Technology in Biomedicine. 2008 Mar;12(2):162-72.

    86. Ford, J.; Roach, B.; Turner, J.; Brown, G.; Greve, D.; Wible, C.; McCarthy, G.; Lauriello, J.; Belger, A.; Mueller, G.; Calhoun, V.; Preda, A.; Keator, D.; O’Leary, D.; Lim, K.; Glover, G.; Potkin, S.; Mathalon, D. Tuning in to the voices: A multi-site fMRI study of auditory hallucinations. Schizophrenia Bulletin. 2009 Jan;35(1):58-66.

  • 87. Potkin, S.G., Turner, J.A., Fallon, J.A., Keator, D.B., Guffanti, G., Macciardi, F., FBIRN. Gene Discovery Through Imaging Genetics - Identification of Two Novel Genes Associated with Schizophrenia. Molecular Psychiatry. 2009 Apr;14(4):416-28.

    88. Potkin, S.G., Turner, J.A., Guffanti, G., Lakatos, A., Torri, F., Keator D.B., Macciardi F. Genome-wide strategies for discovering genetic influences on cognition and cognitivie disorders: methodological considerations. Cognitive Neuropsychiatry. 2009;Jul;14(4):391-418.

    89. Abe, S., Preda A., Turner J., Keator D.B., Potkin S.G., and F. Birn. "DTI Co-registration Method Comparison Based on DTI Tractography Analysis in the Human Brain." Neuroimage 47 (2009): S51.

    90. Fallon, J., Keator, D.B. Commentary on “In silico modeling system: a national research resource for simulation of complex brain disorders.”. Alzheimer’s Dementia. 2009; Jan: 5(1):5-6.

    91. Keator D.B., Mukherjee J., Preda A., Highum D., Lakatos A., Gage A., Potkin S.G.. "Dopamine D2 and D3 receptor occupancy of cariprazine in schizophrenic patients." Schizophrenia Bulletin, 2009; vol. 35, pp. 154-154.

    92. Keator, D.B., Wei, D., Gadde, S., Bockholt, H., Grethe, J.S., Marcus, D., Aucoin, N., Ozyurt, B. Derived Data Storage and Exchange Workflow for Large-Scale Neuroimaging Analyses on the BIRN Grid. Front Neuroinformatics. 2009;3:30.

    93. Lakatos A., Derbeneva O., Younes D., Keator D.B., Bakken T., Lvova M., Brandon M., Guffanti G., Reglodi D., Saykin A., Weiner M., Macciardi F., Schork N., Wallace D., Potkin S., ADNI. Association between mitochondrial DNA variations and Alzheimer’s Disease in the ADNI cohort. Neurobiology of Aging. 2010;31(8):1355-63.

    94. Ozyurt I.B., Keator D., Wei D., Fennema-Notestine C., Pease K., Bockholt B., Grethe J. Federated Web-accessible Clinical Data Management within an Extensible NeuroImaging Database. Neuroinformatics. 2010;23(1):98-106.

    95. Amen DG, Newberg A, Thatcher R, Jin Y, Wu J, Keator D, Willeumier K. Impact of playing American professional football on long-term brain function. J Neuropsychiatry Clin Neurosci. 2011 Fall;23(1):98-106.

    96. Gadde S., Aucoin N., Grethe J.S., Keator D.B., Marcus D.S., Pieper S., FBIRN, MBIRN, BIRN-CC. XCEDE: An Extensible Schema for Biomedical Data. Neuroinformatics. 2011 Apr 9.

  • 97. Borghammer P, Hansen SB, Eggers C, Chakravarty MM, Vang K, Aanerud JF, Hilker R, Heiss WD, Rodell A, Munk OL, Keator D, and Gjedde A. Glucose metabolism in small subcortical structures in Parkinson’s disease. Acta Neurol Scand. 2011.

    98. Helmer KG, Ambite JL, Ames J, Ananthakrishnan R, Burns G, Chervenak

    AL, Foster I, Liming L, Keator D, Macciardi F, Madduri R, Navarro JP, Potkin S, Rosen B, Ruffins S, Schuler R, Turner JA, Toga A, Williams C, Kesselman C; for the Biomedical Informatics Research Network. Enabling collaborative research using the Biomedical Informatics Research Network (BIRN). J Am Med Inform Assoc. 2011 Apr 22.

    99. Van Erp, TGM, Chervenak A., Kesselman C., D'Arcy M., Sobell J.,

    Keator D., Dahm L. et al. "Infrastructure for sharing standardized clinical brain scans across hospitals." In Bioinformatics and Biomedicine Workshops (BIBMW), 2011 IEEE International Conference on, pp. 1026-1028. IEEE, 2011.

    100. Rasmussen J., Lakatos A., Van Erp T., Kruggel F., Keator D.B., Fallon J.,

    Potkin S., Alzheimer’s Disease Neuroimaging Initiative. Empirical derivation of the denominator region for computing degeneration sensitive 18fluorodeoxyglucose ratios in Alzheimer’s Disease based on the ADNI study. Biochim Biophy Acta - Molecular Basis of Disease. 2012 Mar;1822(3):457-66.

    101. Glover G.H., Mueller B.A., Turner J.A., Van Erp T.G, Liu T., Greve D.,

    Voyvodic J., Rasmussen J., Brown G., Keator D.B., Calhoun V.D., Lee H., Ford J., Mathalon D., Diaz M., O’Leary D., Gadde S., Preda A., Lim K., Wible C., Stern H., Belger A., McCarthy G., Ozyurt B., Potkin S.G., FBIRN. Function Biomedical Informatics Research Network Recommendations for Prospective Multi-Center Functional Magnetic Resonance Imaging Studies. Journal of Magnetic Resonance Imaging. 2012 Feb 7.

    102. Poline J.B., Breeze J., Ghosh S., Gorgolewski K., Halchenko Y., Hanke

    M., Haselgrove C., Helmer K., Keator D.B., Marcus D., Poldrack R., Schwartz Y., Ashburner A., Kennedy D. Data sharing in neuroimaging research. Frontiers in Neuroinformatics. 2012; 6:9.

    103. Chervenak A.L., van Erp T.G., Kesselman C., D’Arcy M., Sobell J., Keator D., Dahm L., Murray J., Law M., Hasso A., Ames J., Macciardi F., Potkin S.G. A system architecture for sharing de-identified, research-ready brain scans and health information across clinical imaging centers. Studies in Health Technology and Informatics. 2012; 175:19-28.

    104. Keator D.B., Fallon J.H., Lakatos A., Fowlkes C., Potkin S.G., Ihler A. Feed-Forward Hierarchical Model of the Ventral Visual Stream Applied to

  • Functional Brain Image Classification. Journal of Human Brain Mapping. 2012 Jul 30.

    105. Keator, D. "Modality Neutral Techniques for Brain Image

    Understanding." Machine Learning and Interpretation in Neuroimaging. 2012: 84-92.

    106. Keator D.B., Helmer K., Steffener J., Turner J.A., Van Erp T.G.M.,

    Gadde S., Ashish N., Burns G.A., Nichols B.N. Towards structured sharing of raw and derived neuroimaging data across existing resources. Neuroimage. 2013 Nov 15;82:647-61

    107. Potkin, S.G., Keator D.B., Kesler-West M.L., Nguyen D.D., VanErp

    T.G.M., Mukherjee J., Shah N., Preda A. D2 Receptor Occupancy Following Lurasidone Treatment in Patients with Schizophrenia or Schizoaffective Disorder. CNS Spectrums, 2013 Sep 30:1-6.

    108. Rafii M.S., Baumann T.L., Bakay R.A.E, Ostrove J.M., Siffert J., Fleisher A.S., Herzog C.D., Barba D., Pay M., Tuszynski M.H., Salmon D., Kordower J.H., Bishop K., Keator D.B., Potkin S.G., Bartus R.T. A phase 1 study of sterotactic gene delivery of AAV2-NGF for Alzheimer’s disease. Alzheimer’s Disease & Dementia 2014 Jan 7.

    109. Van Erp TG, Greve DN, Rasmussen J, Turner J, Calhoun VD, Young S,

    Mueller B, Brown GG, McCarthy G, Glover GH, Lim KO, Bustillo JR, Belger A, McEwen S, Voyvodic J, Mathalon DH, Keator D, Preda A, Nguyen D, Ford JM, Potkin SG, Fbirn. A multi-scanner study of subcortical brain volume abnormalities in schizophrenia. Psychiatry Res. 2014;222(1-2):10-6.

    110. Van Erp TGM, Stark C., Rasmussen J., Turner J., Calhoun V., Razzak S.,

    Lim K.O., Mueller B., Brown G., Bustillo J., Vaidya J., McEwen S., Voyvodic J., Belger A., Mathalon D., Keator D.B., Preda A., Nguyen D., Ford J., Potkin S.G.. "Hippocampal Subfield Volume Abnormalities in Individuals with Schizophrenia." Neuropsychopharmacology, 2014; vol. 39, pp. S500-S500.

    111. Lee, H.J., Preda A., Ford J.M., Mathalon D.H., Keator D.B., Van Erp

    T.G.M., Turner J.A., Potkin S.G.. "Functional Magnetic Resonance Imaging of Motor Cortex Activation in Schizophrenia." Journal of Korean medical science. 2015; 30, no. 5: 625-631.

    112. Wang L., Alpert K., Calhoun V., Keator D.B., King M., Kogan A.,

    Landis D., Tallis M., Potkin S.G., Turner J.A., Amite J.L. SchizConnect: Mediating Schizophrenia Neuroimaging Databases for Large-Scale Integration. Neuroimage Special Issue on Brain Imaging Repositories. 2015.

  • 113. Keator, D.B., Ihler, A. Crystal Identification in Positron Emission Tomography Using Probabilistic Graphical Models. Nuclear Science, IEEE Transactions on. 62.5 (2015): 2102-2112.

    114. Ambite, J. L., Tallis, M., Alpert, K., Keator, D. B., King, M., Landis, D., Konstantinidis, G., Calhoun, V. D., Potkin, S. G., Turner, J. A., & Wang, L. (2015) SchizConnect: Virtual Data Integration in Neuroimaging. Data Integr Life Sci, 9162:37-51.

    115. Keator D.B., Van Erp T.G, Glover G.H., Mueller B.A., Turner J.A., Liu T., Greve D., Voyvodic J., Rasmussen J., Brown G., Calhoun V.D., Lee H., Ford J., Mathalon D., Diaz M., O’Leary D., Gadde S., Preda A., Lim K., Wible C., Stern H., Belger A., McCarthy G., Ozyurt B., Potkin S.G., FBIRN. The Function Biomedical Informatics Research Network Data Repository. Neuroimage Special Issue on Brain Imaging Repositories. 2016.

    116. Miller RL, Vergara V, Keator DB, Calhoun VD. A Method for Inter-

    temporal Functional Domain Connectivity Analysis: Application to Schizophrenia Reveals Distorted Directional Information Flow. IEEE Trans Biomed Eng. August 16, 2016.

    117. Gorgolewski K.J.,Auer T.,Calhoun V.,Craddock C.,Das S.,Duff E.,Flandin

    G.,Ghosh S.,Halchenko Y.,Handwerker D.,Hanke M.,Keator D.B.,Li X.,Maumet C.,Michael Z.,Nichols B.N.,Nichols T.,Poline J.B.,Roken A.,Schaefer G.,Sochat V.,Turner J.A.,Varoquaux G.,Poldrack R. The Brain Imaging Data Structure: a standard for organizing and describing outputs of neuroimaging experiments. Data Science Journal. 2016.

    118. Maumet C., Auer T., Bowring A., Chen G., Das S., Flandin G., Ghosh S.,

    Glatard T., Gorgolewski K., Helmer K., Jenkinson M., Keator D.B., Nichols N, Poline J.B., Reynolds R., Sochat V., Turner J., Nichols T. Sharing brain mapping statistical results with the neuroimaging data model. Scientific Data. In Press.

    119. Doran E, Keator D.B., Head E., Phelan M.J., Kim R., Totoiu M., Barrio

    J., Small G., Potkin S.G., Lott I. Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer’s Disease: The role of APP. Journal of Alzheimer’s Disease. In Press.

    Book Chapters, other

    120. Keator, D.B. Information Management in Distributed Biomedical Collaboratories. Methods Mol Biol: Biomedical Informatics. 2009;569:1-23.

  • 121. Liu T.T., Glover G., Mueller B., Greve D.N., Rasmussen J., Voyvodic J.T., Turner J.A., Van Erp T.G.M, Mathalon D., Andersen K., Lu K., Brown G.G., Keator D.B., Calhoun V.D., Lee H.J., Ford J.M., Diaz M., O’Leary D.S., Gadde S., Preda A., Lim K.O., Wible C.G., Stern H.S., Belger A., McCarthy G., Ozyurt I.B., Potkin S.G., FBIRN. "Quality assurance in functional MRI." fMRI: From Nuclear Spins to Brain Functions, pp. 245-270. Springer US, 2015.

    122. Turner J.A., Pasquerello D., Turner M.D., Keator D.B., Alpert K., King

    M., Landis D. Calhoun V.D., Potkin S.G., Tallis M., Ambite J.L., Wang L. "Terminology Development Towards Harmonizing Multiple Clinical Neuroimaging Research Repositories." Data Integration in the Life Sciences, pp. 104-117. Springer International Publishing, 2015.

    Journal Articles, other

    123. Le Caillec J.M., Pentland A.S., Turner J.A., Potkin S.G., Brown G.G.,

    Keator D.B., McCarthy G.G. et al. "BOOTSTRAP METHODS IN SIGNAL PROCESSING." IEEE Signal Processing Magazine, 2007.

    124. Turner, J.A., Potkin, S.G., Brown, G.G., Keator, D.B., McCarthy, G.,

    Glover, G.H. Neuroimaging for the diagnosis and study of mental disorders. IEEE Signal Processing Magazine, 2007; 24(4), 112-11.

    125. Lei W., Alpert K., Calhoun V., Keator D.B., King M., Kogan A., Landis

    D., Tallis M., Potkin S.G., Turner J.A., Amite J.L. "Schizconnect: A one-stop web-based resource for large-scale schizophrenia neuroimaging data integration." Schizophrenia Bulletin, 2015; vol. 41, pp. S279-S279.

    126. Keator D.B., Ihler A. "An Evaluation of Sparse Inverse Covariance

    Models for Group Functional Connectivity in Molecular Imaging." arXiv preprint arXiv:1510.08508 (2015).

    Journal Publications, Under Review

    127. Nichols B.N., Ghosh S.G., Auer T., Grabowski T., Maumet C., Keator D.B., Pohl K., Poline J.B. Building a Web of Linked Data Resources to Advance Neuroscience Research. Nature Neuroscience. 2016 – Under Review.

    Medical Visualization Publications

    128. Kaplan, Sadock, et. al. Comprehensive Textbook of Psychiatry, 2000.

  • 129. “The Journal of the California Alliance for the Mentally Ill”. Weisburd, DE. Volume 8, No. 3, 1997.

    130. “The California Psychologist: Neuropsychology Special Edition”. Lees-

    Haley, P. Volume 30, No. 8, Aug 1997. Medical Visualization Publications

    131. NOVA , “Can Science Stop Crime”, 2012.

    132. CourtTV, “John Couey Trial”, 2007.

    133. CBS News, “48 Hour Mystery”, 2006.

    134. A&E, “Love Chronicals”, 2000.

    135. Discovery Magazine, “FEAR”, 1997.

    136. ABC News, “The Pulse”, 1998.

    137. Community Outreach, “Alliance for the Mentally Ill: Brain Imaging Center”, Mental Health Association of Orange County, 1998.

    138. Discovery Magazine, “Inside the Mind of a Murderer”, 1999.

    Patents

    1. Using magnetic resonance imaging to generate brain image phenotype and corelating scanning variance with preferential nervous system disorders; bioinformatics. S Potkin, JH Fallon, F Macciardi, J Turner, D Keator - US Patent App. 11/974,516, 2007.

    DIVERSITY Neuroinformatics and Data Sharing Task Force of International Neuroinformatics Coordinating Facility, Contributing Member (http://www.incf.org/activities/our-programs/datasharing/neuroimaging-task-force ) - Participate in international data standards working group. This group promotes diversity by inclusion in activities and improving data sharing worldwide to provide researchers in less developed nations with access to data for scientific discovery. REFERENCES David Kennedy, Ph.D. Professor Director - Division of Neuroinformatics

  • Department of Psychiatry University of Massachusetts Medical Center 508-856-8228 [email protected] Hal Stern, Ph.D. Ted and Janice Smith Family Foundation Dean and Professor of Statistics Donald Bren School of Information and Computer Science University of California, Irvine 949-824-7405 [email protected] Steven L. Small, Ph.D., M.D. Professor and Chair Department of Neurology University of California, Irvine 714-456-7352 [email protected] Steven G. Potkin, M.D. Professor Department of Psychiatry and Human Behavior University of California, Irvine 949-824-8061 [email protected] Jean-Baptiste Poline, Ph.D. Research Scientist Helen Wills Neuroscience Institute University of California, Berkley 510-643-3340 mailto:[email protected] Jessica Turner, Ph.D. Associate Professor Department of Psychology Georgia State University 404-413-6211 mailto:[email protected] James Fallon, Ph.D. Professor – Emeritus Department of Psychiatry and Human Behavior University of California, Irvine 949-294-4292

  • mailto:[email protected] Ira Lott, M.D. Professor Emeritus of Pediatrics and Neurology Director, Down Syndrome Program Department of Neurology University of California, Irvine 714-456-5333 mailto:[email protected] Carl Kesselman, Ph.D. Dean’s Professor, Epstein Department of Industrial and Systems Engineering Fellow, Information Sciences Institut Viterbi School of Engineering Professor, Preventive Medicine Keck School of Medicine University of Southern California 310-448-9338 [email protected]