curriculum vitae panagiotis an.georgoulias, m.d., phcurriculum vitae p. an. georgoulias (assoc....

CURRICULUM VITAE

Panagiotis An.Georgoulias, M.D., Ph.D

Assoc. Professor of Nuclear Medicine

Department of Nuclear Medicine, Faculty of Medicine

School of Health Sciences, University of Thessaly

Larissa, 2015

UNIVERSITY OF THESSALY

SCHOOL OF HEALTH SCIENCES

FACULTY OF MEDICINE

Curriculum Vitae P. An. Georgoulias (Assoc. Prof. Nuclear Medicine, U.Th.)

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Summary of scientific work

Published work: 91 manuscripts, 73 presentations

Published papers in peer-reviewed international journals 91 1st Author in 22 2nd Author in 10 Last Author in 16

Published papers in peer-reviewed national journals 6 Published Proceedings 4

Presentations in international congresses 73 Presentations in national congresses 82 Book chapters 9 Books 1

Total Impact Factor: 203.8

Citations: 702 h-Index: 14


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JOURNAL IMPACT FACTOR

(Journal Citation Reports, JCR, 2012)

JOURNAL I.F

International Journal of Biochemistry & Cell Biology 4.152

Reproductive Biology and Endocrinology 2.140

Angiology 1.647

Contrast Media and Molecular Imaging 2.872

Medical Oncology 2.147

Acta Haematologica 0.894

Pharmaceutical Development and Technology 1.333

Journal of Asthma 1.848

Gynecological Endocrinology 1.303

Journal of Biomedical Nanotechnology (JBN) 5.256

Reproductive Sciences 2.064

Journal of Pharmaceutical Sciences 3.130

Journal of Clinical Endocrinology and Metabolism 6.430

Nuclear Medicine Communications 1.379

Journal of Instrumentation (JINST) 1.656

The Scientific World Journal 1.730

Journal of Clinical Densitometry 1.713

In Vivo 1.219

COPD 2.310

Oncology 2.165

Lung Cancer 3.392

Pharmacogenomics 3.857

European Journal of Nuclear Medicine and Molecular Imaging 5.114

Diabetologia 6.487

Journal Of Endocrinological Investigation 1.654

Clinical and Experimental Ophthalmology 1.964

BMC Gastroenterology 2.110

Journal Of Experimental and Clinical Cancer Research 3.066

Current Alzheimer Research 3.676

Fertility and Sterility 4.174


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Archives of Gynecology and Obstetrics 1.330

Respiratory Medicine 2.585

Hormone and Metabolic Research 2.145

Neurosurgery Quarterly 0.089

Journal of Human Genetics 2.365

Clinical Endocrinology (Oxf) 3.396

Human Reproduction 4.670

Annals of Nuclear Medicine 1.410

Journal of Clinical Neuroscience 1.253

Clinical Nuclear Medicine 2.955

International Journal of Cardiology 5.509

Hellenic Journal of Nuclear Medicine 0.931

Journal of Nuclear Cardiology 2.847

Human Genomics 2.69

Journal of BUON 0.706

Nuklearmedizin 1.322


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PERSONAL DETAILS

Surname: Georgoulias

Name: Panagiotis

Father’s Name: Anastasios

Date of Birth: August 11th 1967

Place of Birth: Athens

Address: 60 Anastasopoulou str., Larissa

Telephone : 0030-241350-2918

E-mail: [email protected]

[email protected]

CURRENT POSITION

(i) Assoc. Professor of Nuclear Medicine, Department of Nuclear Medicine,

Faculty of Medicine, School of Health Sciences, University of Thessaly.

(ii) Head of Nuclear Medicine Lab, Faculty of Medicine, School of Health

Sciences, University of Thessaly / Head of Nuclear Medicine department,

Univesrity Hospital of Larissa.

(iii) Honorary Scientific Collegue of Nuclear Medicine department, NIMITS

Hospital.

EDUCATION

Graduate from 10th Lyceum of Athens, Attica, 1985

Distinction “Excellent” (Graduation Degre: 19.8/20)

mailto:[email protected]


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UNDERGRADUATE STUDIES

MD Degree, Faculty of Medicine, National and Kapodistrian University of Athens,

September, 1991.

Distinction “Very Good”, (Graduation Degree: 8.1/10).

POSTGRADUATE STUDIES

(i) Clinical Pathology Residency in the Department of Pathology of General

Hospital of Crestena (1991 – 1992)

(ii) Nuclear Medicine Residency in the Department of Nuclear Medicine of

NIMITS Hospital (1993 – 1996), Title of Residency in Nuclear Medcine

(1996).

(iii) Fellowship in the PET/PET-CT, PET-CT Departmet, University Hospital of

Berlin (Charite Medical School - Virchow Klinicum), Germany, (without

payment, for a time period of approximately 7 months in total, during my

summer leave of 2004-2011).

MILITARY OBLIGATION

I have lawfully fullfield my military obligations as a resident doctot of Nuclear

Medicine.

PhD Thesis

Title:

“Assessment of myocardial perfusion and function in patients with coronary

artery disease subjected to angioplasty, using myocardial SPECT (with 201Tl

both at stress and rest) and radioisotopic ventriculography (MUGA-at rest and

after isometric exercise)”.

Supervisor: Karkavitsas Nikolaos.

PhD Title in Nuclear Medicine, Faculty of Medicine, University of Crete

Distinction: “Excellent”, 1998.


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FOREIGN LANGUAGES & COMPUTER SKILLS

English I speak and write English fluently.

Computer skills Microsoft Office: Word, Excel, Powerpoint, Outlook.

CLINICAL TRAINING AND PROFESSIONAL EXPERIENCE

1. Residency in Clinical Pathology, Department of Pathology, General Hospital of

Krestena, (1991-1992).

2. Residency in Nuclear Medicine, Department of Nuclear Medicine, NIMITS

Hospital (1993-1996).

3. Honorary scientific collaborator in the Department of Nuclear Medicine,

NIMITS Hospital (1996).

4. Resident in Nuclear Medicine (during my military service), Department of

Nuclear Medicine, NIMITS Hospital (1997-1998).

5. Director of the Nuclear Medicine department, Diagnostic Center of “Christos

Christou” (1998-2004).

6. Honorary scientific collaborator in the department of Nuclear Medicine, NIMITS

Hospital (1996).

7. Lecturer (part time) in the department of Nuclear Medicine, Faculty of

Medicine, School of Health Sciences, University of Thessaly (2nd Semester,

academic year: 2003 – 2004).

8. Lecturer in the department of Nuclear Medicine, Faculty of Medicine, School of

Health Sciences, University of Thessaly, (2004 – 2009).

9. Assist. Professor in the department of Nuclear Medicine, Faculty of Medicine,

School of Health Sciences, University of Thessaly, (2009 - σήμερα).

10. Head –Scientific Director of Nuclear Medicine department, University of

Thessaly – University Hospital of Larissa (2004 – up to date).

11. Fellowship (no salary) in the PET - CT department of University Hospital of

Berlin (Charite Medical School -Virchow Klinicum), Germany (7 months in total

during the time period of 2004 - 2011).


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ADMINISTRATIVE AND ORGANIZING ACTIVITY

1. Director and Physician in charge of the Nuclear Medicine department of the

Diagnostic Center “Christos Christou”.

2. Elected member of the Board of Directors of the Hellenic Society of Nuclear

Medicine and Biology (HSNM&B) and treasurer of HSNM&B (2004-2008).

3. Member of the General Assembly of the Faculty of Medicine of University of

Thessaly during the academic year 2005 – 2006, 2008-2009, 2013-2014.

4. Scientific Director of the department of Nuclear Medicine in the University

Hospital of Larissa (2004 - 2009).

5. Chairman (along with Mr. V. Prassopoulos) of the Sumposium entitled

“Developments in Nuclear Medicine”, Volos, September 12-14, 2008.

6. Head of the Nuclear Medicine Lab. Faculty of Medicine, School of Health

Sciences, University of Thessaly / Head of the Department of Nuclear

Medicine in the University Hospital of Larissa, Thessaly (2009 – up to date).

7. Member in committees regarding specifications, evaluation and

commissioning of medical systems (PET/CT camera, gamma-camera, CT

etc), as well as in committees regarding expendable equipment related to my

specialty in the University Hospital of Larissa (2004- up to date).


Medicine and Biology (HSNM&B) (2010-up to date).

9. Elected Member of the Educational Commtttee of the Hellenic Society of

Nuclear Medicine and Biology (HSNM&B) (2013).

10. Organizer and chairman of the postgraduate seminar entitled: “Applications of

Nuclear Medicine in Neurology” (Larissa, Greece, March 6th, 2013).

11. Member of the Organizing Comitee of Nuclear Medicine Residents Lessons,

2013-2015.

12. Member of the Organizing Comitee of the seminar “Evolutions of Nuclear

Medicine: highlights ftom the International Meetings (SNM, EANM)”, of the

Hellenic Society of Nuclear Medicine and Biology (HSNM&B), Athens,

2014, 2015.

13. Organizer of the Continuous Education Seminars in Nuclear Medicine,

Faculty of Medicine, University of Thessaly (2010-2015).


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MEMBER OF SCIENTIFIC COMMITEES AND SOCIETIES

1. European Association of Nuclear Medicine (EANM)

2. EANM Cardiovascular Comittee

3. Hellenic Society of Nuclear Medicine and Biology (HSNM&B)

4. Working Groups of the Hellenic Cardiological Society

5. Hellenic Society of Nuclear Medicine

SPECIFIC POSITIONS

1. Elected as the National Representative of the Hellenic Society of Nuclear

Medicine and Biology in the European Association of Nuclear Medicine (2002

- 2004).


Medicine and Biology (HSNM&B) and treasurer of HSNM&B (2004-up to

date).

3. Member of the Examination Committee in the Faculty of Medicine of the

University of Thessaly (2006- up to date).

4. Member of the Examination Review Committee in the Faculty of Medicine of

the University of Thessaly (2006- up to date).

5. National Lead for the First ECNC Survey of Myocardial Perfusion Scintigram

in Europe (2006-2007).

6. National Lead for the Second ECNC Survey of Myocardial Perfusion

Scintigram in Europe (2007-2008).

7. EANM National Liaison (Cardiovascular Working Group) of the Greek Society

of Nuclear Medicine and Biology in the European Council of Nuclear

Cardiology (2007-2011).

8. Member of the EANM Cardiovascular Committee (2007 – 2011).

9. Elected member of the Educational Commtttee of the Hellenic Society of

Nuclear Medicine and Biology (HSNM&B) (2013).

TEACHING EXPRERIENCE


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Α. Undergraduate

1. Professor of the optional course “Elements of Nuclear Medicine’’, which is

tutored to the students of the Faculty of Medicine in the University of

Thessaly (9th and 11th semester), since 2005- up to date.

2. Teaching Nuclear Medicine within the scope of the obligatory course of

Diagnostic Imaging (8th-9th semester, Professor: I. Fezoulidis) during the

academic years of 2003-2004 (part time Lecturer), 2004-2009 (as a

Lecturer of Nuclear Medicine), and from 2009-up to date as an Assist.

Professor of Nuclear Medicine.

3. Teaching within the scope of the optional course “Radiatioprotection”

during the academic years of 2009-up to date (Professor: C. Kappas).

4. Teaching within the scope of the obligatory course “Medical Responsibility

and Ethics”, during the academic year 2012-2013.

5. Physician in charge in the department of Nuclear Medicine of NIMITS

Hospital, for the clinical training of students from the Department of

Radiologic Technologists at ATEI of Athens, during the academic years of

1994-1995 and 1997 –1998.

6. Participating in the Training Program of the School of Applied

Mathematical and Physical Sciences, National Technical University of

Athens (NTUA), during the academic year 2006-2007.

7. Participating in the Training Program of the Department of Biochemistry

and Biotechnology of the University of Thessaly, during the academic year

of 2010-2011.

8. Participating in students’ presentations during Student Conferences 2005,

2006.

Β. Postgraduate

1. Teaching the course of “Nuclear Cardiology” in the International Masters

Program of Medical Physics, entitled “Interdepartmental Post-Graduate

Program of Studies in Medical Physics”, under the collaboration of the


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Faculty of Medicine and the Department of Physics of the Univesity of

Patras (2006-2014).

2. Organizing and participating in the Program of Continuous Education in

Nuclear Medicine, Department of Nuclear Medicine, Faculty of Medicine,

University of Thessaly (2010-2015).

3. Participating in the educational program of the Department of Cardiology

of the University of Thessaly (2012-2013).

4. Participating in the educational program of the Diagnostic Radiology –

Medical Imaging Department, Faculty of Medicine, University of Thessaly

(2007-2008, 2012-2013).

5. Participating in the postgraduate seminars of continuous education of the

Hellenic Society of Nuclear Medicine and Biology (HSNM&B) (1998-2015).

6. Participating in the postgraduate courses of Nuclear Medicine residents

(2001-2014).

7. Participating in the educational program of the Nuclear Cardiology Work

Groups of the Hellenic Cardiology Society (2005-2012).

8. Participating in the educational program (courses for Specialized Medical

Personnel) of the Department of Orthopaedic Surgery and Trauma,

Faculty of Medicine, University of Thessaly, (2005-2006, 2006-2007,

2010-2011, 2014-2015).

9. Participating in the Program of Educational Activities of the Department of

Hematology, Faculty of Medicine, University of Thessaly (2009-2010).

10. Participating in the Educational Program of the Department of

Pneumonology, Faculty of Medicine, University of Thessaly (2009 – 2010).

11. Participating in the 4th Annual Education Program of the Department of

Pathology, Faculty of Medicine, University of Thessaly, (2011 – 2012).

12. Participating in the 4th Educational Program of Nursing Specialties (2011-

2014).

SUPERVISOR OF Ph.D. THESES

1. “Brain perfusion SPECT imaging in patients with dementia. Evaluation of

perfusion in Broadmann areas using the automated data analysis


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software Neurogam”.

PhD candidate: Varvara Valotassiou.

Department of Nuclear Medicine, Faculty of Medicine, University of Thessaly,

2010.

2. “Development of dedicated gamma-camera imaging systems for

experimental subjects and small organs”.

PhD candidate: Maria Georgiou.


2010.

3. “Investigation of Central Nervous System tumors with Positron Emission

Tomography (PET) – Application of new PET radiopharmaceuticals”.

PhD candidate: Alexandra Nikaki.


2011.

4. “Functional optimization of Positon Emissiotn Tomography systems”.

PhD candidate: Lampros Theodorakis.


2011.

SUPERVISOR OF POST-DOCTORAL THESES

1. “Development of a non invasive system for the early detection of

melanoma with the combined use of acoustic microscopy from 50 up to

100MHz, probe microscopy, optical microscopy and diffuse reflectance

spectroscopy and imaging from 0.4μm up to 10μm”.

Post-Doctoral Researcher: Giorgos Karagiannis.


2012.

CO-SUPERVISOR OF Ph.D. THESES

1. “Combination and evaluation of advanced magnetic resonance and

nuclear medicine techniques in the differential diagnosis of central

nervous system’s lesions”


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PhD candidate: Basiliki Tsitsia.

Faculty of Medicine, University of Thessaly, 2014.

2. “The effect of Anti-Mullerian Hormone and the morphogenetic protein 15

(BMP-15) in the steroid hormone secretion from human follicular cells

culture via Smad5 signal pathway”.

PhD candidate: Ermioni-Dimitra Prapa.


3. “The role of combining HMRS and SPECT imaging in the presurgical

evaluation of cerebral tumors”.

PhD candidate: Ioannis Siassios.


4. “Correlation of serum S-100-A protein levels to the histological type of

intracranial tumors”.

PhD candidate: Charalampos Gatos.

Department of Neurosurgery, Faculty of Medicine, University of Thessaly,

2009

5. “Development of a 3D software for treatment planning and internal dose

calculation in nuclear medicine patients using functional and anatomical

imaging”

PhD candidate: Prokopios Mparmpagiannidis.

Department of Medical Physics, Faculty of Medicine, University of Thessaly,

2009.

MEMBER OF Ph.D. THESES EXAMINATION COMMITTEE

1. “Systematic inflammation and cardiovascular risk factors in chronic

obstructive pneumonopathic (COPD) patients”

PhD candidate: Parthenia Mystridou

Department of Pneumonology, Faculty of Medicine, University of Thessaly,

2014.

2. “Analysis of polymorphism and determination of osteoporosis genes”.

PhD candidate: Theodora Koromila

Department of Biology, School of Sciences, National and Kapodistrian


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University of Athens, 2012.

3. «Ghrelin, adiponectin, resistin and reproduction».

PhD candidate: Dimitrios Sourlas

Department of Gynecology and Obstetrics, Faculty of Medicine, University of

Thessaly, 2011.

4. “Scintigraphic investigation of Lymphomas using the radiolabelled

somatostatin analogue, “99mTc-depreotide”.

PhD candidate: Nikolaos Papandrianos.


2010

5. “Body mass index in patients with asthma and Chronic Obstructive

Pulmonary Disease (COPD): Correlation with metabolic and functional

parameters”.

PhD candidate: Markos Minas.

Department of Pneumonology, Faculty of Medicine, University of Thessaly,

2010.

6. “Monte Carlo Techniques for Electron Radiotherapy”.

PhD candidate: Hiba Omer.


2009.

7. “Study of the three dimensional dose distribution of human body

heterogeneities in radiotherapy, using PC simulation software and

comparison between current calculation algorithms and Monte Carlo

techniques”.

PhD candidate: Miltiadis Tsiakalos.


2005.

CO-SUPERVISOR OF M.Sc. THESES

1. “The Effects Of Physical Activity On Brown Adipose Tissue In Humans”

Master’s Student: Petros Dinas

Department of Physical Education and Sport Science, University of Thessaly,


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2012.

ACADEMIC NOTES FOR MEDICAL STUDENTS

1. “Notes in Nuclear Medicine”

Georgoulias P.

(181 pages of notes for medical students, within the scope of the obligatory

course of “Diagnostic Imaging II” (8th semester), Faculty of Medicine,

University of Thessaly).

2. “Elements of Nuclear Medicine”

Georgoulias P.

(194 pages of notes for medical students, within the scope of the course

“Elements of Nuclear Medicine” (9th and 11th semester), Faculty of Medicine,

University of Thessaly.

BOOK CHAPTERS

1. Diagnostic algorithms regarding the radioisotopic diagnostic examinations in

the field of Nuclear Cardiology (Hellenic Society of Nuclear Medicine and

Biology, 2012).

2. Book Chapter: “Clinical Significance of Tetrofosmin Extracardiac Uptake

During Myocardial Perfusion Imaging” (P.Georgoulias, V. Valotassiou, I.

Tsougos, G. Agelides, N.Demakopoulos), “Coronary Angiography / Book 2",

ISBN 979-953-307-235-6 (Intech Open Access Publisher, 2011).

3. Book Chapter: “The Clinical Use of SPECT and PET Molecular Imaging in

Alzheimer’s Disease” (Valotassiou V., Sifakis N., Papatriantafyllou J.,

Angelidis G. and Georgoulias P.), in the book entitled "The Clinical Spectrum

of Alzheimer’s Disease - The Change Towards Comprehensive Diagnostic and

Therapeutic Strategies", ISBN 978-953-307-993-6 (Intech Open Acess

Publisher, 2011).

4. Book Chapter: “Applications of SPECT and PET/CT Imaging in the Brain

in ICU Patients” (Valotassiou V. Georgoulias P., pg. 861 - 871) in the book of


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Baltopoulou G., Gavala A., Tsigou E., Paschalidis Medical Editions, Athens,

2009.

5. Book Chapter: “Internal Radionuclide Dosimetry Using Quantitative 3-D

Nuclear Medical Imaging” (Tsougos I., Loudos G., Georgoulias P., Nikita

K., Theodorou K., pg. 213-228), “Handbook of Research on Advanced

Techniques in Diagnostic Imaging and Biomedical Applications”, IDEA Group

Inc. Global, 2009.

6. Book Chapter: “Applications of Positron Emission Tomography (PET) in

Radiotherapy’’ (Georgoulias P., Valotassiou V., pg. 229 - 246), in the book

entitled “Radiation Oncology”, by Assist. Professor G.Plataniotis, Athens, 2009.

7. Contributing in the book “Pregnancy and Medical Radiation”, (Kappas C.,

Theodorou K, Mavroeidis P., Komisopoulos G., Annals of the ICRP publication

84, Paschalidis Medical Publications, Athens, 2006.

8. Book Chapter: “The contribution of Nuclear Medicine in Spinal Column

Disorders” (Georgoulias P., Giannakopoulos Ch., pg. 41-58) in the book of

Professor Georgios Sapkas entitled: “Current Subjects of Spinal Column

Disorders”, Kafkas Editions, Athens, 2005.

9. Book: “Nuclear Medicine and Coronary Disease” (Georgoulias P.,

Karkavitsas N.), Parisianos Medical Editions, Athens, 2004.

10. Contributing in the book entitled: “Nuclear Medicine courses” (Professor Lida

Gogou), Stamoulis Publications, Athens, Greece, 1999.

REVIEWER IN PEER-REVIEWED JOURNALS

1. Nuclear Medicine Communications

2. International Journal of Cardiology

3. Southern Medical Journal

4. Hellenic Journal of Nuclear Medicine

5. Recent Patents on Medical Imaging

6. Cardiovascular Diabetology

7. Respiration

8. World Journal of Diabetes

9. Molecular and Cellular Endocrinology


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10. American Journal of Gastroenterology

11. Current Alzheimer Research

12. Heart and Vessels

13. Radiation Oncology

14. Journal of Biomedical Graphics and Computing.

15. World Journal of Cardiovascular Surgery.

16. Basic Research Journal of Medicine and Clinical Sciences

17. Journal of Neurology and Epidemiology

18. BMC Medical Imaging

19. Computer Methods and Programs in Biomedicine

20. The Quarterly Journal of Nuclear Medicine and Molecular Imaging

21. International Research Journal of Public and Enviromental Health

22. Basic Research Journal of Medicine and Clinical Sciences.

MEMBER OF THE EDITORIAL BOARD IN SCIENTIFIC JOURNALS

1. Member of the editorial board of the Hellenic scientif journal

«Aktinotechnologia-Radiationtechnology», (1998-1999).

2. Advisor in the “Hellenic Journal of Nuclear Medicine”, (2007 – 2011).

3. Member of the editorial board of the “Recent Patents on Medical Imaging”

journal, (2009 – up to date).

4. Member of the editorial board of the “World Journal of Diabetes”, (2010- up

to date).

5. Member of the editorial board of the “Hellenic Journal of Nuclear Medicine”,

(2012-up to date).

6. Member of the editorial board of the “Journal of Biomedical Graphics and

Computing”, (2013 - up to date).

7. Member of the editorial board of the “Journal of Neurology and

Epidemiology”, (2013 – up to date).

ORGANIZER - MEMBER OF ORGANIZING AND SCIENTIFIC COMMITTEES IN

CONFERENCES AND SUMPOSIUMS


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1. Member of the Organizing Comitee of Nuclear Medicine Residents Lessons,

2013-2015.

2. Member of the Organizing Comitee of the seminar “Evolutions of Nuclear

Medicine: highlights ftom the International Meetings (SNM, EANM)”, of the

Hellenic Society of Nuclear Medicine and Biology (HSNM&B), Athens,

February 14, 2015.

3. Member of the Scientific (Program) Comitee of the International Congress

on Cardiovascular Technologies (CARDIOTECHNIX 2014), Rome, Italy,

October 25th-26th, 2014.

4. Member of the Scientific (Program) Comitee of the International Congress on

Cardiovascular Technologies (CARDIOTECHNIX 2015), Italy, October,

2015.

5. Member of the Scientific Committee of the 11th Panhellenic Conference of

Nuclear Medicine, Ioannina, May 30th-Jun 1st, 2014.

6. Organizer of the seminar “Evolutions of Nuclear Medicine: highlights ftom the

International Meetings (SNM, EANM)”, of the Hellenic Society of Nuclear

Medicine and Biology (HSNM&B), Athens, February 01, 2014.

7. Member of the Scientific Committee of the seminar entitled: “What does the

clinician neurologist ask from the Nuclear Medicine?”, Thessaloniki,

Greece, December 14th, 2013.

8. Member of the Scientific Committee of the seminar entitled: “The role of

Nuclear Medicine in the investigation of brain diseases”, Thessaloniki,

Greece, March 9th, 2013.

9. Organizer of the Post-Graduate Educational Seminar entitled: “Applications

of Nuclear Medicine in Neurology”, Larissa, Thessaly, March 6th, 2013.

10. Member of the Scientific Committee of the “International Congress on

Cardiovascular Technologies”, Vilamoura, 19-23 September, Portugal,

2013.

11. Organizing Continuous Education Seminars in Nuclear Medicine, Faculty of

Medicine, University of Thessaly (2010-2015). During the academic years of

2011-2012, 2012-2013, 2013-2014 and 2014-2015 the program was

accredited with CME credits from the Panhellenic Medical Society, based on

the EACCME – UEMS criteria.

12. Member of the Scientific Committee of the 11th Panhellenic Conference of


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Nuclear Medicine, Athens, March 30th-April 1st, 2012.

13. Member of the Scientific Committee of the 22nd Confernce of the Hellenic

Society of Nuclear Medicine, Alexandroupoli, April 8-10, 2012.

14. Chairman of the Scientific Committee of the 10th Panhellenic Conference of

Nuclear Medicine, Kalampaka, September 10-12, 2010.

15. Member of the Organizing Committee of the 21st International Conference

of Nuclear Medicine, Thessaloniki, May 7 – 9, 2010.

16. Member of the Scientific Committee of the scientific meeting “Neuroimaging

in Nuclear Medicine”, Thessaloniki, March 20th, 2010.

17. Chairman (with Mr. V. Prassopoulos) and member of the Scientific

Committee of the Symposium “Developments in Nuclear Medicine”, Volos,

September 12-14, 2008.

18. Member of the Scientific Committee of the 4th International Conference of

the Hellenic Society of Nuclear Medicine, Thessaloniki, November 7-9,

2008.

19. Organizing the “Educational Meeting of Sells Group’’ of GE HEALTHCARE

Medical Diagnostics Hellas SA, in collaboration with the Department of

Urology of the University Hospital of Larissa, Larissa, February 21st, 2007.

20. Member of the Scientific Committee of the 12th Hellenic Scientific

Conference for Medical Students, Larissa, May 5-7, 2006.

21. Member of the Organizing Committee of the 6th Panhellinic Conference of

Nuclear Medicine, Athens, April 4-5, 1998.

CHAIRMAN IN KEYNOTE SPEECHES IN CONFERENCES

1. Chairman in the session entitled: “EANM”, of the seminar “Evolutions of

Nuclear Medicine: highlights ftom the International Meetings (SNM,

EANM)”, of the Hellenic Society of Nuclear Medicine and Biology (HSNM&B),

Athens, February 14, 2015.

2. Chaiman in the session: “PET/CT Imaging & Optimization”, of the 8th

European Congress on Medical Physics, Athens, 11-13 September, 2014.

3. Chaiman in the session: “Functional and Molecular Imaging of Myocardial

Perfusion and Viability”, of the Panhellenic Conference of Nuclear Medicine,

Ioannina, May 30-Jun 1, 2014.


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4. Chairman in the keynote speech of the Dr. Maria Koutelou entitled: “Cell

Therapy of Ischaemic and non-Iaschaemic Heart Failure” of the

Panhellenic Conference of Nuclear Medicine, Ioannina, May 30-Jun 1, 2014.

5. Chairman in the international scientific conference entitled “Treatment of

Epilepsies II”, Larisa, 16-18 Μay, 2014.

6. Chairman in the session entitled: “SNM”, of the seminar “Evolutions of



Athens, February 01, 2014.

7. Chairman of the session entitled “Neurodegenerative Dementia”, during the

post-graduate educational seminar entitled “Applications of Nuclear Medivine

in Neurology, Larissa, March 6th, Thessaly, 2013.

8. Chairman in the session entitled: “SNM”, of the seminar “Evolutions of



Athens, November 24, 2012.

9. Annotator in the session entitled: «Combination of Imaging Techniques:

Presentation of Interesting cases”, of the 7th Congress of Clinical

Cardiovascular Disorders, Pylos, Greece, May 24-26, 2012.

10. Chaiman in the session: “Studies in Cardiology”, of the Panhellenic

Conference of Nuclear Medicine, Athens, March 30-April 1, 2012.

11. Chairman in the session entitled: “Rememebering the basics” of the task

group of Nuclear Cardiology and Computed Tomography, in the Annual

Meeting of Task Groups of the Hellenic Cardiology Society, Thessaloniki,

Greece, February 18, 2012.

12. Chairman in the session entitled: “Interesting cases in Nuclear Medicine”,

in the 15th Postgraduate Seminars, Athens, Greece, January 21, 2012.

13. Chairman in the session entitled: “The role of Nuclear Medicine in brain

tumor imaging”, in the 22nd Conference of the Hellenic Society of Nuclear

Medicine, Alexandroupolis, Greece, April 8-10, 2011.

14. Chairman in the session of Oral Presentationss in the 21st Conference of

Nuclear Medicine with international participation, Thessaloniki, Greece, May

7- 9, 2010.


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15. Chairman in the session entitled: “Epilepsy: From the lab to clinical

practice”, in the international scientific conference entitled “Therapeutic

Approaches of Epilepsy Patients”, Larissa, Greece, May 25-27, 2010.

16. Chairman in the session entitled: ‘’Myocardial perfusion SPECT:

radiopharmaceuticals, protocols, imaging, techniques”, in the Seminars

of Nuclear Cardiology, Athens, Greece, May 24, 2008.

17. Chairman in the keynote speech of Assist. Professor Zisimopoulos entitled:

“Radioanosologic and radioanosometric examinations in Nuclear

Medicine, and their clinical importance in tumor diagnosis: Our

experience” in the 18th Scientific Meeting entitled “Postgraduate and

Research topiscs of Nuclear Medicine”, Thessaloniki, Greece, November 3,

2007.

18. Chairman in the “Myoview Club Meeting”. (One of the keynote speakers

was the Chairman of EANM Prof. Carrio I.), Loutraki, Greece, September 28-

30, 2006.

19. Chairman in the keynote speech of Dr. van Isselt, entitled: “Implications of

iodine metabolism for radioiodine treatment of Grave’s

hyperthyroidism”, in the 3rd Conference of Nuclear Medicine in North Greece

with international participation, Thessaloniki, Greece, November 4-6, 2005.

20. Chairman in the keynote speech of Dr. Tousimis A.J., entitled: “Near infrared

and short wave-length photon radiation for imaging and destruction of

malignant tumors in homosapiens”, in the 3rd Conference of Nuclear

Medicine in North Greece with international participation, Thessaloniki,

Greece, November 4-6, 2005.

INVITED SPEAKER IN CONFERENCES, SEMINARS AND POSTGRADUATE

LECTURES

1. “Main clinical applications of myocardial perfusion SPECT imaging”, in

the postgraduate educational courses of the Cardiology department in the

University of Thessaly, Larissa, December 10th, 2014.


21

2. “Studies of myocardial perfusion SPECT – imaging principles –

processing techniques –artifacts’’, in the postgraduate courses of Nuclear

Medicine residentsl, Athens, Greece, December 13th, 2014.

3. “Basic principles of SPECT myocardial perfusion imaging – techniques -

radiotracers’’, in the postgraduate courses of the Cardiology Clinic, University

of Thessaly, Larissa, Greece, January 22th, 2013.

4. “Studies of myocardial perfusion SPECT – imaging principles –

processing techniques –artifacts’’, in the postgraduate courses of Nuclear

Medicine residents, “Alexandra” Hospital, Athens, Greece, December 14th,

2012.

5. “Basic principles and indications in Nuclear Medicine’’, in the

postgraduate courses and clinical-laboratory meetings of the Diagnostic

Radiology - Medical Imaging department, University of Thessaly, Larissa,

Greece, Novemeber 20th, 2012.

6. “Myocardial Perfusion Scintigraphy in Clinical Practice’’, 2nd Educational

Program of Continuous Education in Nuclear Medicine, Department of Nuclear

Medicine, Larissa, January 24th, 2012.

7. “Study of myocardial perfusion SPECT and topic review”, in the 24th

Educational Seminar of the Hellenic Society of Nuclear Medicine, Thessaloniki,

Greece, March 10th, 2012.

8. “Basic Principles of PET in Oncology’’, in the 20th University Conference of

Radiology, Larissa, Greece, November 10-13, 2011.

9. «Subacute Thyroiditis De Quervain: The role of Nuclear Medicine in the

diagnosis”, in the 4th Postgraduate Seminars of the Pathology department in

the University of Thessaly, Larissa, Greece, November 10th, 2011.

10. “Clinical Applications of Nuclear Medicine’’, in the 4th Education Courses of

Nursing Specialties, Larissa, Greece, (Academic years: 2011-2013).

11. “Basic principles of PET-CT. Clinical applications in myoskeletal

tumors”, in the postgraduate educational program of the Orthopedics

department, in the University of Thessaly, Larissa, Greece, March 22nd, 2011.

12. “Myocardial perfusion SPECT protocols – Processing techniques –

Artifacts”, in the postgraduate courses of Nuclear Medicine residents, Athens,

Greece, February 14th, 2011.


22

13. “Basic Principles of PET”, in the postgraduate courses of the Pneumonology

department in the University of Thessaly, Larissa, Greece, February 18th,

2010.

14. “The contribution of imaging methods in the disorders of the diabetic

foot – SPECT, 9th Panhellenic Seminar, Larissa, Greece, December 10-12th,

2010.

15. “Nuclear Medicine and Haematology”, in the postgraduate courses of the

Heamatology department in the University of Thessaly, Larissa, Greece, 2009-

2010.

16. «Myocardial perfusion SPECT: Principles, radiopharmaceuticals,

exercise test protocols, clinical significance”, in the postgraduate courses

of the Hellenic Society of Nuclear Medicine and Biology for Nuclear Medicine

residents.

17. «Perspectives of Nuclear Cardiology - Imaging of fragile fibrinoid

plaque», in the educational program of the Task Group of Nuclear Cardiology,

Athens, Greece, January 23rd, 2009.

18. “The contribution of myocardial SPECT in clinical practice”, in the 18th

University Conference of Radiology, Ioannina, Greece, November 15th, 2008.

19. “Molecular Imaging” in the Educational program 2007-2008 of the Task

Group of Nuclear Cardiology, of the Hellenic Cargiology Society, Athens,

Greece, May 23rd, 2008.

20. “The contribution of PET-CT in the differential diagnosis of the upper

abdomen. Techniques - indications and clinical applications”, in the

educational courses of the Diagnostic Radiology – Medical Imaging

department in the University of Thessaly, Larissa, Greece, April 17th, 2008.

21. «Identification of primary myoskeletal tumors and infections using

SPECT», in the educational courses of the Orthopedic Surgery and Trauma, in

the University of Thessaly, Larissa, Greece, March 12th, 2007.

22. “Radiopharmaceuticals for myocardial perfusion SPECT”, in the

educational program of the Task Group of Nuclear Cardiology, Hellenic

Cardiology Society, Athens, Greece, February 23rd, 2007.

23. “Myocardial perfusion SPECT. Important radiopharmceuticals –

techniques - clinical contribution”, in the educational seminar of GE


23

HEALTHCARE Medical Diagnostics Hellas SA, Larissa, Greece, February 21st,

2007.

24. “Identification of artifacts and exocardiac tracer uptake in myocardial

perfusion SPECT”, in the educational program 2005-2006, of the Task Group

of Nuclear Cardiology, of the Hellenic Cardiology Society, Athens, Greece,

May 19th, 2006.

25. “Bilateral 201Tl uptake in the breasts during myocardial perfusion

SPECT”, in the Seminars of Continuous education 2005-2006, entitled

“Intersting cases in Nuclear Medicine”, Athens, Greece, April 8th, 2006

26. “Basic Principles of bone scintigraphy in Orthopedics”, in the educational

program of the Orthopedic Surgery and Trauma department, of the Unuversity

of Thessaly, Larissa, Greece, January 30th, 2006.

27. “Diagnosis of coronary artery disease with radioisotopic imaging of

myocardial perfusion”, in the 8th Cardiological Conference of Central Greece,

Larissa, Greece, October 21-23rd, 2005.

28. “Evolutions in Nuclear Medicine”, in the Scientific Meeting organized by GE

Healthcare, Athens, Greece, May 6th, 2005.

29. “Radiosynoviorthesis” in the seminar entitled “Therapeutic Applications of

Nuclear Medicine”, in the program of continuous education, Athens, Greece,

January 10th, 2004.

30. Presentation of an interesting case regarding myocardial perfusion SPECT

in the seminars of continuous education 2002-2003, entitled “Interesting cases

in Nuclear Medicine”, Athens, Greece, May 10th, 2003.

31. Presentation of an interesting case regarding myocardial perfusion SPECT

in the 4th Postgraduate Seminars of Continuous Medical Education –

Presentation of Characteristic Cardiological Cases, Athens, Greece, May 26th,

2001.

32. Presentation of an interesting cardiological case in the 4th Postgraduate

Seminars of Continuous Medical Education – Presentation of Characteristic

Cardiological Cases, Athens, Greece, May 26th, 2001.

33. Annotator in the Seminars of Cardiological Cases organized by the Hellenic

Society of Nuclear Medicine and Biology, Athens, Greece, May 26th, 2001.


24

34. “Radioisotopic Synoviorthesis”, in the 6th postgraduate seminars entitled

“Nuclear Medicine in Orthopedics” of the Hellenic Society of Nuclear Medicine

and Biology, Athens, Greece, March 31st, 2001.

35. Presentation of an interesting case of three-phase bone scintigraphy in the

2nd Postgraduate Seminars of Continuous Medical Education entitled

‘’Presentation and discussion of interesting cases”, Athens, Greece, November

18, 2000.

36. “Υ-90 in intra-articular and fluid accumulations” in the 5th postgraduate

seminar of continuous medical education entitled “Therapeutic applications of

radioisotopes (besides thyroid) in Greece. New updates”, Athens, Greece,

October 30th, 1999.

37. Presentation of an interesting cardiological case in the 2nd postgraduate

seminar – Presentation and Discussion of characteristic cardiological cases, of

the 5th Seminar of continuous medical education, Athens, Greece, May 8th,

1999.

38. Presentation of an interesting myocardial perfusion SPECT case in the

postgraduate seminar entitled “Presentation of Interesting Diagnostic Cases” of

the 4th Seminars of Contitnuous Medical Education in Nuclear Medicine,

Athens, Greece, October 3rd, 1998.

39. Presentation of an interesting case of “Diagnosis of choloperitoneum using

hepatobiliary scanning” in the 4th postgraduate seminars of continuous

medical education entitled “Presentation of Interesting Diagnostic Cases”,

Athens, Greece, October 3rd, 1998.

40. Presentation of an interesting cardiological case in the postgraduate

seminar of continuous medical education entitled “Presentation of

characteristic cases”, Athens, Greece, May 30th, 1998.

RESEARCH ACTIVITY

1. Myocardial perfusion SPECT and MUGA in patients undergoing perqutaneous

transluminal coronary angioplasty (1993 - up to date).

1. Application of Tc-99m-tetrofosmin for the evaluation of myocardial perfusion


25

and function (1994 – up to date).

2. Application of pharmacological tests in combination with tomographic

myocardial perfusion imaging (1994 – up to date).

3. Scintigraphic detection of experimentally induced thrombi by a 99mTc

decapeptide (1998 – up to date).

4. Participation in the multicentre and multinational study entitled “Multicenter

study of patient survival after radioanosotherapy with a monoclonic antibody.

Multinational study in patients with ovarian cancer using the Y-90 radiolabelled

HMFG1 antibody” (Smart Study, 1999-2004, Budget: 102,400 euro).

5. Participation in the clinical study entitled: “Imaging of lung cancer using Tc-

99m radiolabelled porphyrin” (Budget: 40,000 euro) (1998 – 1999).

6. Participation in the research program “The effect of skeletal traction in the

vascularization of the femur head. Experimental study in rabbits”(1999 – 2001).

7. Study of the prognostic parameters during exercise treadmill testing (2001 – up

to date).

8. Evaluation of brain SPECT in patients with Parkinson’s disease (2004 – up to

date).

9. Development of a 3D treatment planning system for external and internal

dosimetry in Nuclear Medicine and Radiotherapy patients. Project “Pythagoras

II”. (Budget: 80,000 euro) (2005 – 2008).

10. Application of brain perfusion SPECT in patients with Frontotemporal

Dementia and Alzheimer’s disease (2005 – up to date).

11. Investigation of gene expression in patients with myocardial ischemia (2005 –

up to date).

12. Evaluation of neurotransmitter and enzyme levels as markers of psychokinetic

status in post-traumatic patients (2006 – up to date).

13. Evaluation of the inflammatory factor S-100A12 in patients with automatic

subarachnoid haemorrage (2007 – up to date).

14. Evaluation of the inflammatory factor S-100A12 in patients with idiopathic

infectious bowel disease (2007 – up to date).

15. Clinical evaluation of ghrelin, leptin and adiponectin in patients with bronchial

asthma (2007 – up to date).


26

16. Investigating the role of ghrelin, leptin and adiponectin in paroxysmal asthma.

(2007 – up to date).

17. Investigating the role of ghrelin, leptin and adiponectin in heart failure (2007 –

up to date).

18. Investigating the role of leptin and adiponectin in lung cancer patients (2008 -

up to date).

19. Evaluation of leptin, adiponectin, osteocalcin and IGF-1 in patients with COPD

(2008 - up to date).

20. Study of osteoporosis factors (2007 - up to date).

21. Participation in the clinical study entitled: “Study of the genetic profile of

homosexuality and schizophrenia” (2008 - up to date).

22. Collaborating in the study entitled: “The role of ghrelin in prolactin and

gonadotrophin hormone secretion in women” (2007 – 2011).

23. Collaborating in the clinical study entitled: “The effect of applying an non-

invasive mechanical ventilation in the metabolic disorders of patients with

COPD” (2009 - up to date).

24. Study of fetuin levels in patients with idiopathic inflammatory bowel disease


25. Collaborating in the study of biochemical markers of cachexia in metastatic

lung cancer patients (2008 - up to date).

26. Correlation of smoking and aging with AMH levels (2008 - 2010).

27. Study of the role of ghrelin in open angle glaucoma patients (2008 – 2010).

28. Development of dedicated gamma-camer imaging systems for experimental

subjects and small organs (2010 – up to date).

29. Development and evaluation of an open-source software for the iterative

reconstruction and attenuation-scatter correction of SPECT images (2009 – up

to date).

30. Investigation of Central Nervous System tumors with Positron Emission

Tomography (PET) – Application of new PET radiopharmaceuticals (2011 - up

to date).

31. “Functional optimization of Positon Emissiotn Tomography (PET) systems”


32. «Evaluation of new diagnostic and prognostic parameters in myocardial

perfusion SPECT. Application of new techniques.’’ (Budget: 40,000 euro)


27

(2011-up to date).

33. “Study of gene mutations of Toll-like Receptor-4 and fetuin-A in the

pathogenesis, diagnosis and therapy of large intestine cancer and idiopathic

infectious bowel disease” (2011 – up to date). (Budget: 20,000 euro).

34. “Oprimization of Clinical Protocols for Personalized Cancer Diagnosis and

Treatment Using Advanced Anthropomorphic Phantoms”, Program

“Archimedes”, Budget: 81,000 euro.

35. “Exercise, smoking, & alcohol: Investigation of mechanisms & interventions for

prevention, cessation & awareness – escape”. Budget: 525,000 euro (Funded

by “Thalis” program, 2011 - up to date).

RESEARCH, ACADEMIC AND CLINICAL COLLABORATION WITH

INTERNATIONAL AND NATIONAL INSTITUTES

PET/PET-CT, PET-CT Department, University Hospital of Berlin (Charite

Medical School - Virchow Klinicum).

Colorobbia Italia S.p.A, Ce.Ri.Col. Centro Ricerche Colorobbia, Vinci, Italy.

Technical University of Darmstadt, Germany.

Department of Nuclear Medicine, NIMITS Hospital, Athens.

Department of Cardiology, NIMITS Hospital, Athens.

Department of Biology, National and Kapodistrian University of Athens.

Department of Nuclear Medicine, Faculty of Medicine, University of Crete.

Faculty of Medicine, University of Patras.

Radiopharmaceutical Quality Control Department, “Demokritos”, National

Center for Scientific Research.

School of Applied Mathematical and Physical Sciences, National Technical

University of Athens (NTUA).

Pediatric Department of Orthopedics, “K.A.T”, University Hospital of Athens.

Department of Radiologic Technologists at TEI of Athens.

Oncological Hospital of Athens «Agioi Anargyroi».

Department of Oncology, “Athens Medical Group”.

Department of Gynecology and Obsretrics, Democritus University of Thrace.


28

Department of Gynecology and Obsretrics, University of Crete.

Department of Cardiology, General Hosptial of Karditsa, Thessaly.

Department of Biochemistry and Biotechnology, University of Thessaly.

“Ygeia” Hospital (Athens).

Department of Physical Education and Sport Science, University of Thessaly.

PRESENTATIONS IN NATIONAL CONGRESSES

(Total number: 83)

PRESENTATIONS IN INTERNATIONAL CONGRESSES

(Total number: 79)

1. Hypoperfusion of subgenual cortex: an early finding of Alzheimer’s

disease?”

Valotassiou V., Papatriantafyllou J., Sifakis N., Tzavara C., Tsougos I.,

Psimadas DD, Kapsalaki E., Chatjigeorgiou G., Georgoulias P.

27th Annual Congress of the European Association of Nuclear Medicine,

Gothenburg, Sweden, October 18-22, 2014.

2. “FLT-PET/CT in reccurent brain tumors: Visual and semiquantitative

assessment”

Nikaki A., Prassopoulos V., Fillipi V., Savvidou D., Tsougos I., Vlachou V.,

Kosmidis P., Nomikos P., Gogos K., Efthymiadou R., Georgoulias P.


Gothenburg, Sweden, October 18-22, 2014.

3. “Positron emission tomography’s newest technologies to address

present and future applications: A focus on time of flight”.


29

Theodorakis L., Loudos G., Prassopoulos V., Kappas C. Tsougos I.,

Georgoulias P.

8th European Congress on Medical Physics, Athens, 11-13 September,

2014.

4. “Correlation of advanced magnetic resonance imaging and brain

SPECT for the pre-surgical evaluation of cerebral tumour patients”.

Tsougos. I, Tsitsia V., Valotassiou V., Siasios I., Fountas K.,

Kapsalaki E., Theodorou K., Fezoulidis I., Georgoulias P.


2014.

5. “Contribution of FLTAPET/CT in metastatic brain tumors”.

Nikaki A., Efthymiadou R., Tsougos I., Prassopoulos V., Filippi V.,

Vlachou F., Savvidou D., Pipikos T., Andreou I., Georgoulias P.


2014.

6. “Effect of anti-Müllerian hormone (AMH) and bone morphogenetic

protein 15 (BMP-15) on steroidogenesis in primary-cultured human

luteinized granulosa cells”

Prapa E., Vasilaki A., Katsiani E., Georgoulias P., Messini C.,

AnifandisG., DafopoulosK., MessiniI.E.

29th Annual Meeting of the European Society of Human Reproduction and

Embryology, Munichl, Germany, Juln 29th-July 2nd , 2014.

7. “FLT-PET/CT for brain lesions evaluation: A semi-quantitative

approach in a prospective study”.

Nikaki A., Prassopoulos V., Fi S., Fillippi V., Kechagias D., Vlachou F.,

Menisoglou S., Razi E., Nomikos P., Efthymiadou R., Georgoulias P.

26th Annual Congress of the European Association of Nuclear Medicine, Lyon,

France, October 19-23, 2013.

8. “In vivo imaging of hEGFR-targeted PEG-based nanocarrier containing

magnetic nanonparticles for cancer diagnosis and therapy”.

Psimadas D., Comes-Franchini M., Baldi G., Fragogeorgi E., Ravagli C.,

Tsotakos T., Bouziotis P, Georgoulias P., Loudos G.


30



9. “Radiolabeling and biodistribution properties comparison of hybrid

nanoparticles bearing CoFe2O4 and Fe3O4 magnetic cores”.

Psimadas D., Baldi G., Ravagli C., Tsotakos T., Fragogeorgi E., Comes-

Franchini M., Valotassiou V., Georgoulias P., Loudos G.



10. “Differential diagnosis of Progressive Supranuclear Palsy and

Corticobasal Degeneration from behavioural variant of Frontotemporal

Dementia using 99mTc-HMPAO and Broadmann areas mapping.

Comparison with normal data base”.

Valotassiou V., Papantriantafyllou J., Sifakis N., Tzavara Ch., Tsougos I.,

Psimadas D., Kapsalaki E., Chadjigeorgiou G., Georgoulias P.



11. “Use of 99mTc-HMPAO SPECT with Broadmann areas mapping for the

assessment of language impairment in Corticobasal

Degeneration/Progressive Supranuclear Palsy and language variants of

Frontotemporal Dementia”.

Valotassiou V., Papantriantafyllou J., Sifakis N., Tzavara Ch., Tsougos I.,

Psimadas D., Kapsalaki E., Chadjigeorgiou G.,Fezoulidis I., Georgoulias P.



12. “Evaluation of space occupying brain lesions with 18F-FLT or 18F-FCH

PET fused with MRI. Preliminary data of a prospective study”.

Nikaki A., Kechagias D., Vlachou F., Andreou I., Gogou L., Filippi V., Dalianis

K., Efthimiadou R., Prassopoulos V., Georgoulias P.


Milan, Italy, October 27-31, 2012 (Eur J Nucl Med Mol Im, Suppl 2, S2, S175,

2012).


31

13. “Alzheimer’s disease and Progressive Non-Fluent Aphasia: Evaluation of

perfusion differences using 99mTc-HMPAO SPECT and Brodmann Areas

Mapping”.


Psimadas D., Makrypoulias K., Kournouti M., Kapsalaki E., Chadjigeorgiou G.,

Georgoulias P.



2012).

14. “Patterns of perfusion deficits in Semantic dementia and Progressive

non-fluent aphasia: a 99mTc-HMPAO SPECT study with Brodmann Areas

Mapping”.


Psimadas D., Ziaka A., Makrypoulias K., Kournouti M., Kapsalaki E.,

Chadjigeorgiou G., Georgoulias P., 25th Annual Congress of the European

Association of Nuclear Medicine, Milan, Italy, October 27-31, 2012(Eur J Nucl

Med Mol Im, Suppl 2, S2, S547, 2012).

15. “Brain Perfusion with 99mTc-HMPAO SPECT in Differentiating

Alzheimer’s disease from Progressive Supranuclear Palsy and

Corticobasal Degeneration: Analysis Using Brodmann Areas Mapping”


Psimadas D., Ziaka A., Kapsalaki E., Chadjigeorgiou G., Georgoulias P.



2012).

16. “18F-FLT PET fused with MRI in primary and metastatic brain tumors.

Prospective study- Preliminary results”.

Nikaki A., Kechagias D., Vlachou F., Andreou I., Gogou L., Filippi V., Gogos

K., Efthimiadou R., Prassopoulos V., Georgoulias P.



2012).


32

17. “Leptin, adiponectin and ghrelin levels in female patients with asthma

during stable and exacerbation periods”.

Tsaroucha A., Daniil Z., Malli F., Georgoulias P., Minas M., Kostikas K.,

Bargiota A., Gourgoulianis K.I.

Annual Congress of European Respiratory Society, Vienna, Austria,

September 1-5, 2012.

18. “The effects of exercise on Beta endorphin and alcohol urges in

alcoholic patients”.

Jamurtas A.Z, Zourbanos N., Georgoulias P., Mouzas O., Bletsou A., Souliou

S., Psifos V., OIkonomou D., Theodorakis Y.

17th Annual Congress of the European College of Sport Science, Bruges,

Belgium, July 4-7, 2012.

19. “Metmorfin reduces the expression of corticotrophin releasing hormone

and urocortin in the endometrium of normal women”.

Dafopoulos K., Vrekoussis T., Chalvatzas N., Messini C.I, Kalantaridou S.,

Georgoulias P., Messinis I.E., Makrigiannakis A.


Embryology, Instabul, Turkey, July 1-4, 2012.

20. “Identification of TGFΒ signaling pathway genes expression in

peripheral blood and bone segments of osteoporotic postmenopausal

women”.

Koromila T., Dailiana Z., Samara S., Chassanidis CG., Georgoulias P.,

Aleporou-Marinou V., Kollia P.

ORS, San Francisco, California, USA, February 4 - 7, 2012.

21. “Photon dose kernels dataset for nuclear medicine dosimetry, using

GATE Monte Carlo Toolkit”.

Papadimitroulas P., Loudos G., Georgoulias P., Kagadis G.

IEEE, Nuclear Science Symposium and Medical Imaging Conference,

Valencia, Spain, 23-29 October, 2011.

22. “The contribution of brain perfusion SPECT with Brodmann Areas

mapping in the differential diagnosis of Alzheimer’s Disease from

Frontotemporal Lobar Degeneration”.


33




Birmingham, UK, October 15-19, 2011 (Eur J Nucl Med Mol Im, Suppl 2,

S327, 2011).

23. “Brain perfusion SPECT with Brodmann Areas mapping in the

differential diagnosis of Alzheimer’s Disease from behavioural variant of

Frontotemporal Lobar Degeneration”.


Kapsalaki E., Chadjigeorgiou G., Georgoulias P.


Birmingham, UK, October 15 - 19, 2011, (Eur J Nucl Med Mol Im, Suppl 2,

S324, 2011).

24. “Evaluation of perfusion differences in Semantic Dementia and

Alzheimer’s Disease using 99mTc-HMPAO SPECT with automated

Brodmann Areas mapping”.




Birmingham, UK, October 15-19, 2011. (Eur J Nucl Med Mol Im, Suppl 2,

S323, 2011).

25. “Leptin and Adiponectin levels in Idiopathic Pulmonary Fibrosis”.

Malli F., Georgoulias P., Valotassiou V., Tsilioni I., Gourgoulianis K., Daniil Z.

ERS Annual Congress, Amsterdam, Netherlands, September 26 - 29, 2011.

26. “Elimination half-life of Anti-Muellerian hormone in the human”.

Griesinger G., Dafopoulos K., Buendgen N., Cascorbi I., Georgoulias P.,

Zavos A., Messinis C., Diedrich K., Messinis I.


Embryology, Stockholm, Sweden, July 3 – 6, 2011 (Human Reproduction,

Suppl. 1, PP15, 2011).

27. “Leptin signaling functional status and BNP levels in ambulatory heart

failure patients”.


34

Georgoulias P., Giammouzis G., Tziolas N., Karayannis G., Alexandridis E.,

Zavos N., Koutrakis K., Rovithis D., Parisis C., Tryposkiadis F.

ICNC 10 -Nuclear Cardiology and Cardiac CT, Amsterdam, Netherlands, May

15 – 18, 2011.

28. “Leptin concentrtion increases relatevily to the functional status and is

associated with epicardial fat thickness in ambulatory heart failure

patients”.

Giammouzis G., Tziolas N., Georgoulias P., Karayannis G., Chamaidi A.,

Zavos N., Koutrakis K., Sitafidis G., Skoularigis J, Tryposkiadis F.

ICNC 10 - Nuclear Cardiology and Cardiac CT, Amsterdam, Netherlands, May

15 – 18, 2011.

29. “Evaluation of an Imaging Gamma Probe Based On R8900U-00-C12

PSPMT’’.

Georgiou M., David S., Papadimitroulas P., Fysikopoulos E., Bregou A.,

Loudos G., Georgoulias P.

ΙΕΕΕ, ΜΙC-NSS, Valencia, Spain, 2011 (Δημοσίευση στα πρακτικά του

Συνεδρίου ως πλήρες άρθρο, 2011).

30. “Association of adipokines, markers of bone metabolism, bone mineral

density and body composition in men with Chronic Obstructive

Pulmonary Disease”.

Fountoulis G.A., Minas M., Georgoulias P., Fezoulidis I., Gourgoulianis K.,

Vlychou M.

3rd Joint Meeting of the European Calcified Tissue Society and the

International Bone and Mineral Society, Athens, Greece, May 7 – 11, 2011

(Bone, Suppl.48, S190, 2011).

31. Correlations of the Mini Nutritional Assessment (MNA) with laboratory

markers of cachexia in metastatic lung cancer patients”.

Gioulbasanis I., Giannousi Z., Georgoulias P., Vlaxostergios P., Ghosh S.,

Maragoudi E., Siagouli M., Papandreou C., Mavroudis D., Georgoulias V.

3rd International Congress on Nutrition and Cancer, Bodrum, Turkey, October

20 - 24, 2010.


35

32. “Frontotemporal Dementia and Alzheimer’s Disease: evaluation of brain

perfusion in specific Brodmann Areas using automated 3-D voxel based

analysis”.

Valotassiou V., Papatriantafyllou J., Sifakis N., Tsougos I., Tzavara C.,

Fothiadaki A., Makrypoulias K., Zerva C., Georgoulias P..

23rd Annual Congress of the European Association of Nuclear Medicine,

Vienna, Austria, October 9 - 13, 2010, (Eur J Nucl Med Mol Im, Suppl 2, S395,

2010).

33. “Stress lung/ heart ratio as an index of left ventricular dysfunction and

multi-vessel coronary disease”.

Kotsalou I., Karfis I., Poulakis M., Karydas J., Georgoulias P., Zoumboulidis

A., Lazaridis K., Dimakopoulos N.



2010).

34. “Impact of FXIIIA1, FII, FV, FGB and PAI1 polymorphisms on myocardial

perfusion: correlation with myocardial Single Photon Emission

Computed Tomographic Imaging”.

Satra M., Samara M., Wozniak G., Kontos A., Valotassiou V., Tsougos I.,

Kollia P., Georgoulias P.



2010).

35. “Experimental and simulation studies for the optimization of dedicated

scintimammography cameras”.

Georgiou M., Loudos G., David S., Georgoulias P.



2010).

36. “Ghrelin concentration in the aqueous humour and plasma in open angle

glaucoma patients”.

Katsanos A., Dastirdou A., Georgoulias P., Cholevas P., Kotoula M., Tsironi

E..


36

EVER, Crete, Greece, October 6 - 9, 2010.

37. “Metabolic syndrome in COPD Patients without Cardiovascular

Comorbidities: Co-Existence or a Different COPD Phenotype?”

Minas M., Papaioannou A., Mystridou P., Karetsi E., Georgoulias P., Liakos

N., Pournaras S., Gourgoulianis K., Kostikas K.

ERS Annual Congress, Barcelona, Spain, September 18 - 22, 2010.

38. “Plasma and aqueous humour levels of ghrelin in open glaucoma

patients”.

Dastirdou A., Katsanos A., Georgoulias P., Cholevas P., Kotoula M., Tsironi E.

9th Congress of the European Glaucoma Society, Madrid, Spain, September

12-17, 2010.

39. “Association between novel polymorphisms in the CER1 gene and

fracture risk in greek osteoporotic women”.

Koromila T., Dailiana Z., Samara S., Chassanidis C., Georgoulias P.,


9th ΕHS, Αthens, Greece, September 9–11, 2010.

40. “Progesterone is the ovarian factor that terminates the endogenous LH

surge in women”.

Zavos A., Dafopoulos K., Georgoulias P., Messini C.I., Verikouki C., Messinis

I.E.


Embryology, Rome, Italy, June 27 – 30, 2010, (Human Reproduction, Suppl.1,

I313, 2010).

41. “Effect of ghrelin and metoclopramide on prolactin secretion in normal

women”.

Messini C.I, Dafopoulos K., Chalvatzas N., Georgoulias P., Anifandis G.,

Messinis I.E.


Embryology, Rome, Italy, June 27 – 30, 2010, (Human Reproduction, Suppl.1,

S308, 2010).

42. “Pattern recognition system for semi-automated detection of

myocardium defects on spect images”.


37

Papadimitroulas P., Varsamidis A., Glotsos D., Kalatzis I., Georgoulias P.,

Loudos G., Kostopoulos S., Cavouras D., Nikiforidis G.

4th International Conference from Scientific Computing to Computational

Engineering, Athens, Greece, July 7 - 10, 2010.

43. “Association of CER1 polymorphisms with osteoporosis in Greek

women; Correlations with biochemical markers and bone density”.

Koromila T., Dailiana Z., Samara S., Chassanidis C., Georgoulias P.,


37th ECTS, Glasgow, Scotland, June 26 - 20, 2010.

44. “Free Paper Session: association of CER1 polymorphisms with

osteoporosis in greek postmenopausal women”.

Koromila T., Dailiana Z., Chassanidis C., Samara S., Michalitsis S., Tsavara

C., Georgoulias P., Malizos K., Aleporou-Marinou V., Kollia P.

11th EFORT, Madrid, Spain, June 2 - 5, 2010.

45. “The effect of smoking on inhibin B levels in normal fertile women”.

Dafopoulos A., Dafopoulos K., Koutlaki N., Georgoulias P., Galazios G.,

Maroulis G., Liatsikos S., Zografou C., Tsikouras P., Limberis V.

14th World Congress of Gynecological Endocrinology, Firenze, Italy, March 4-

7, 2010.

46. “Inflammatory Bowel Disease-Induced Changes in Circulating Levels of

Α2 - Heremans-Schmid Glycoprotein (Fetuin A)”.

Manolakis A. C., Kapsoritakis A. N., Georgoulias P., Tiaka E. K., Oikonomou

K., Christodoulidis G., Valotassiou V. J., Potamianos S. P.

5th ECCO Congress, Prague, Czech Republic, February 25 - 27, 2010, (JCC,

Suppl.1, S38, 2010).

47. “Systemic and airway inflammation and the presence of emphysema in

patients with COPD”.

Papaioannou A., Mazioti A., Kiropoulos T., Tsilioni I., Koutsokera A., Tanou

K., Nikoulis D., Georgoulias P., Zakynthinos E., Gourgoulianis K., Kostikas K.

ERS Annual Congress, Vienna, Austria, September 12-16, 2009, (Eur

Respiratory Journal, Suppl.53, S475, 2009).


38

48. “Clinical significance of serum adipokines levels in cancer”.

Kerenidi T., Tsaroucha A., Lada M., Georgoulias P., Mystridou P.,

Gourgoulianis K., Kostikas K.

ERS Annual Congress, Vienna, Austria, September 12 - 16, 2009, (Eur

Respiratory Journal, Suppl.53, S475, 2009).

49. “Effect of ghrelin and thyrotropin releasing hormone on prolactin

secretion in normal women”.

Messini C.I, Dafopoulos K., Chalvatzas N., Georgoulias P., Messinis I.E


Embryology, Amsterdam, Netherlands, 28 June-1 July, 2009, (Human

Reproduction, Suppl. 1. I74, 2009).

50. “Epicardial Fat Thickness is Reduced in Non- Cachectic Heart Failure

Patients With Depressed But Not in Those With Preserved Ejection

Fraction”.

Tziolas N., Georgoulias P., Karayannis G., Giamouzis G., Demopoulos V.,

Skoularigis J., Butler J., Triposkiadis F.

Heart Failure 2009, Nice, France, May 30 – June 2, 2009, (Eur Jour Heart

Failure, Suppl.2, 2009).

51. “Long-Term prognostic value of Tc-99m Tetrofosmin early post-stress

lung uptake during myocardial perfusion imaging”.

Valotassiou V., Demakopoulos N., Tzavara C., Giannakou S., Tsougos I.,

Keramida G., Orfanakis A., Georgoulias P.

22nd Annual Congress of the European Association of Nuclear Medicine,

Barcelona, Spain, October 10 – 14, 2009, (Eur J Nucl Med Mol Im, Suppl 2,

S285, 2009).

52. “Role of 123-I-FP brain SPECT studies in clinical management of

Parkinsonian Syndromes”.

Kotsalou I., Karfis I., Georgoulias P., Aygoustatos G., Zoumboulidis A.,

Dimakopoulos N.



S386, 2010).


39

53. “Anatomical regions mediating denial of deficits in Dementia

syndromes”.

Valotassiou V., Papatriantafyllou J., Georgoulias P., Fothiadaki A.,

Makrypoulias K., Zerva C., Sifakis N.



S378, 2010).

54. “Incremental prognostic value of Tc-99m Tetrofosmin early post-stress

lung uptake during gated-spect myocardial perfusion imaging”.

Valotassiou N., Demakopoulos N., Tzavara C, Giannakou., S., Tsougos I.,

Orfanakis A., Georgoulias P.



S319, 2009).

55. “Relationship of stress lung/ heart ratio and multivessel coronary

disease defined by 99mTc- Tetrofosmin myocardial perfusion imaging”.

Kotsalou I., Karfis I., Poulakis M., Georgoulias P., Zoumboulidis A., Karydas I.,

Lazaridis K., Dimakopoulos N.



S312, 2009).

56. “Impact of ACE and APOE polymorphisms on myocardial perfusion:

correlation with myocardial single photon emission computed

tomographic imaging”.

Satra M., Georgoulias P., Wozniak G., Samara M., Kontos A., Tzavara C.,

Valotassiou V., Kollia P.

ICNC9 – Nuclear Cardiology and Cardiac CT, Barcelona, Spain, May 10 - 13,

2009.

57. “Profile of metabolism - related cytokines in myelodysplastic

syndromes’’.

Matsouka P., Bouronikou H., Georgoulias P., Palassopoulou M., Valotassiou

V., Vassilopoulos G., Giannakoulas N., Papadoulis N.


40

10th International Symposium on Myelodysplastic Syndromes (MDS), Patras,

Greece, May 6 - 9, 2009, (Leukemia Research, Suppl.1, S97, 2009).

58. “QSPECT: An open-source software for the iterative reconstruction of

SPECT images”.

Zotos P., Papadimitroulas P., Tsougos I., Georgoulias P., Loudos G.

4th International Meeting of the Hellenic Society of Nuclear Medicine, 7-9

November 2008, Thessaloniki, Greece.

59. “Comparing Parkinson’s Disease scale with scintigraphic stades”.

Kotsalou I., karfis I., Fourlis S., Georgoulias P., Aygoustatos G., Heropoulos

P., Zoumpoylidis A., Dimakopoulos N.

4th International Meeting of the Hellenic Society of Nuclear Medicine, 7-9

November 2008, Thessaloniki, Greece.

60. “Serum S100A12, a marker distinguishing inflammatory bowel disease

from irritable bowel syndrome”.

Kapsoritakis A. N., Georgoulias P.A., Manolakis A. C., Tsikouras A.D.,

Valotassiou V. J., Kapsoritaki A.I., Oikonomou K., Potamianos S. P.

16th United European Gastrenterology Week, Vienna, Austria, October 18 -

22, 2008.

61. “I-123 Ioflupane dopamine transporter spect imaging in Parkinsonian

syndrome diagnosis”.

Bairactaris C., Demakopoulos N., Tripsianis G., Sioka C., Farmakiotis D.,

Vadikolias K., Heliopoulos I., Georgoulias P., Tsougos I., Papanastasiou I.,

Piperidou C.

21st Annual Congress of the European Association of Nuclear Medicine,

Munich, Germany, October 11 – 15, 2008, (Eur J Nucl Med Mol Im, Suppl 2,

S300, 2008).

62. “Incremental prognostic value of 99mTc-Tetrofosmin myocardial gated-

spect in asymptomatic patients after percutaneous coronary

angioplasty”.

Valotassiou V., Demakopoulos N., Tzavara Ch., Giannakou S., Tsougos I.,

Xaplanteris P., Fezoulidis I., Georgoulias P.


41



S186, 2008).

63. “Prognostic value of 99mTc-Tetrofosmin myocardial SPECT in

asymptomatic patients after coronary artery stenting”.

Valotassiou V., Demakopoulos N., Tzavara Ch., Giannakou S., Tsougos I.,

Xaplanteris P., Fezoulidis I., Georgoulias P.



S168, 2008).

64. “Nuclear medicine in Neurology and Psychiatry”.

Iliadis Ch., Wozniak G., Kunz A., Prokopakis D., Valotassiou V., Georgoulias

P..

EANS Winter Meeting 2008, Trondheim, Norway, February 29 - March 2,

2008.

65. “Correlation of rCBF abnormalities and neuropsychiatric symptoms in

degenerative dementias”.

Sifakis N., Papatriantafyllou J., Valotassiou V., Bersimis S., Boulas C.,

Karageorgiou C., Georgoulias P., Zerva C.


Copenhagen, Denmark, October 13 - 17, 2007, (Eur J Nucl Med Mol Im,

Suppl 2, S319, 2007).

66. “Prognostic value of abnormal heart-rate recovery after treadmill testing

in patients with Diabetes Mellitus: Correlation with exercise testing and

myocardial spect parameters”.

Georgoulias P., Valotassiou V., Demakopoulos N., Wozniak G., Xaplanteris

P., Zaganides A., Xydis K., Fezoylidis I.


Copenhagen, Denmark, October 13 – 17, 2007, (Eur J Nucl Med Mol Im,

Suppl 2, S182, 2007).

67. “Hypoperfusion of the orbitofrontal cortex. A reliable sign of FTD?

Valotassiou V., Papatriantafyllou J., Sifakis N., Makrypoulias B., Georgoulias

P., Karageorgiou C., Zerva C.


42


Copenhagen, Denmark, October 13 - 17, 2007, (Eur J Nucl Med Mol Im,

Suppl 2, S133, 2007).

68. “Evaluation of brain perfusion in specific brodmann areas in

frontotemporal dementia and alzheimer’s disease using automated 3-D

voxel based analysis”.

Valotassiou V., Papatriantafyllou J., Sifakis N., Georgoulias P., Karageorgiou

C., Zerva C.

4th International Conference on Imaging Technologies in Biomedical Sciences,

Milos, Greece, September 22 - 28, 2007.

69. “Impact of ACE (INS/DEL), APOB (R3500Q) and APOE (E2/E3/E4)

polymorphisms on myocardial perfusion: correlation with myocardial

Single Photon Emission Computed Tomographic Imaging”.

Wozniak G., Samara M., Georgoulias P., Chiotoglou I., Kontos A., Valotassiou

V., Kollia P.

European Human Genetics Conference, Nice, France, June 16 – 19, 2007,

(Eur Journ Human Genetics, Suppl.1, S238, 2007).

70. “False positive myocardial perfusion imaging in women with left Bundle

Branch Block. The effect of beta-blocker medication”.

Georgoulias P., Demakopoulos N., Wozniak G., Valotassiou V., Giannakou S.,

Ziaka A., Xydis K., Fezoylidis I.

8th International Conference of Nuclear Cardiology, Prague, Czech Republic,

April 29 - May 2, 2007, (Jour Nucl Cardiol, Suppl.2, S25, 2007).

71. “Development of a 3D treatment planning systems for external and

internal dosimetry in radiotherapy”.

Boukis S., Tsougos I., Loudos G., Theodorou K., Georoulias P., Nikita K.,

Kappas C.

3rd International Greek Biotechnology Forum, Athens, Greece, October 5 - 7,

2006.

72. “Pulmonary uptake of 99mTc-Tetrofosmin during exercise (SPECT)

myocardial perfusion imaging. Comparison between different calculating

methods”.


43

Georgoulias P., Demakopoulos N., Xaplanteris P., Wozniak G., Valotassiou

V., Zaganides A., Xydis K., Fezoulidis I.


Athens, Greece, September 30– October 4, 2006, (Eur J Nucl Med Mol Im,

Suppl. 2, S229, 2006).

73. “Early post-stress lung uptake of 99mTc-Tetrofosmin during exercise

(SPECT) myocardial perfusion imaging in the identification of multi-

vessel coronary artery disease”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Wozniak G., Valotassiou

V., Zaganides A., Xydis K., Fezoulidis I.


Athens, Greece, September 30– October 4, 2006, (Eur J Nucl Med Mol Im,

Suppl. 2, S229, 2006).

74. “Abnormal heart - rate recovery immediately after exercise testing in

patients with Diabetes Mellitus: correlation with myocardial ischemic

and chronotropic variables”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Fezoulidis I.


Istanbul, Turkey, October 15 – 19, 2005, (Eur J Nucl Med Mol Im, Suppl. 1,

S167, 2005).

75. “Εarly post-stress lung uptake of Τc-99m Τetrofosmin during exercise

(SPECT) myocardial perfusion imaging. Determination of the upper

normal value”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Xydis K., Fezoulidis I.



S166, 2005).

76. “Heart rate recovery immediately after tredmill testing before and six

months after perqutaneous transluminal coronary angioplasty”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Fezoulidis I.



S166, 2005).


44

77. “Knee radiosynoviorthesis with yttrium-90 colloid in inflammatory joint

disease”.

Georgoulias P., Demakopoulos N., Karras D., Mortzos G., Fezoulidis I.


Helsinki, Finland, September 4 – 8, 2004, (Eur J Nucl Med Mol Im, Suppl. 2,

S478, 2004).

78. “Early post stress pulmonary uptake of Tc-99m tetrofosmin during

exercise (spect) myocardial perfusion imaging”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Mortzos G., Fezoulidis I.



S299, 2004).

79. “Myocardial perfusion spect imaging and radionuclide ventriculography

before and six months after perqutaneous transluminal coronary

angioplasty”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Mortzos G., Karkavitsas N.,

Fezoulidis I.



S298, 2004).

PUBLISHED PROCEEDINGS

1. “Photon dose kernels dataset for nuclear medicine dosimetry, using

GATE Monte Carlo Toolkit”.

Papadimitroulas P., Loudos G., Georgoulias P., Kagadis G.

ΙΕΕΕ, ΜΙc-NSS,2011, Valencia, Spain, 2011 (ΙΕΕΕ, Nuclear Science

Symposium Conference Record, art. no. 6154624: 1390-1394, 2012).

2. “Evaluation of an Imaging Gamma Probe Based On R8900U-00-C12

PSPMT’’.

Georgiou M., David S., Papadimitroulas P., Fysikopoulos E., Bregou A.,

Loudos G., Georgoulias P.

ΙΕΕΕ, ΜΙc-NSS,2011, Valencia, Spain, 2011 (ΙΕΕΕ, Nuclear Science


45

Symposium Conference Record, art. no. 6153764: 4020-4023, 2012).

3. “Pattern recognition system for semi-automated detection of myocardium

defects on SPECT images”.

Papadimitroulas P., Varsamidis A. Glotsos D., Kalatzis I., Georgoulias P.,

Loudos G., Kostopoulos S.,Cavouras D., Nikiforidis G.

4th International Conference from Scientific Computing to Computational

Engineering, Athens, 7-10, July, 2010.

4. My speeches in the educational program of the Task Group of Nuclear

Cardiology of the Hellenic Cardiological Society have been published in the

corresponding proceedings book.


46

PUBLICATIONS IN INTERNATION PEER-REVIEWED JOURNALS

(Total Number: 91)

1. The prevalence of a false-positive myocardial perfusion stress SPET test in

a skinny patient, induced by projection truncation.

Tsougos I., Alexiou S., Theodorou K., Valotassiou V., Georgoulias P.

Hellenic Journal Nuclear Medicine, [Epub ahead of print], 2015.

2. “Non-invasive ventilation (NIV) and homeostatic model assessment

(HOMA) index in stable chronic obstructive pulmonary disease (COPD)

patients with chronic hypercapnic respiratory failure: A Pilot Study”.

Dimoulis .A, Pastaka C., Tsolaki V., Tsilioni .I, Pournaras S., Liakos N.,

Georgoulias .P, Gourgoulianis K.

COPD, [Epub ahead of print], 2014.

3. Multifocal septic osteomyelitis mimicking skeletal metastatic disease in a

patient with prostate cancer.

Alexiou E., Georgoulias P., Valotassiou V., Georgiou E., Fezoulidis .I, Vlychou

M.

Hellenic Journal Nuclear Medicine, [Epub ahead of print], 2015.

4. Otto Hahn (1879-1968): pioneer in radiochemistry and discoverer of

radiotherapeutic mesothorium.

Sgantzos M., Kyrgias G., Georgoulias P., Karamanou M., Tsoucalas G.,

Androutsos G.

J. BUON, 19(3):866-9, 2014.

5. “Association between habitual physical activity and brown adipose tissue

activity in individuals undergoing PET-CT scan”.

Dinas PC., Nikaki A., Jamurtas A.Z, Prassopoulos V., Efthymiadou R.,

Koutedakis Y., Georgoulias .P, Flouris AD.


47

Clinical Endocrionolog [Epub ahead of print], 2014.

6. "Brain perfusion SPECT with Brodmann Areas analysis in differentiating

frontotemporal dementia subtypes".

Valotassiou .V, Papatriantafyllou J., Sifakis N., Tzavara C., Tsougos .I,

PsimadasD., Kapsalaki E., Fezoulidis .I, Hadjigeorgiou G., Georgoulias P.

Curr Alzheimer Res,11(10): 941-54, 2014.

7. “Inhibitory effect of submaximal doses of ghrelin on gonadotropin

secretion in women”.

Messini CI., Dafopoulos K., Malandri M., Georgoulias P., Anifandis .G, Messinis

IE.

Horm Metab Res., 46(1):36-40, 2014.

8. “CER1 gene variations associated with bone mineral density, bone

markers, and early menopause in postmenopausal women”.

Kromila T., Georgoulias P., Dailiana .Z, Ntzani EE., Samara S., Chassanidis C.,


Hum. Genomics, 18(7):21-30, 2013.

9. “The emerging role of Galectin-3 and ST2 in heart failure: practical

considerations and pitfalls using novel biomarkers”.

Karayannis G, Triposkiadis F, Skoularigis J, Georgoulias P, Butler J, Giamouzis

G.

Curr Heart Fail Rep., 10(4):441-9, 2013..

10. “A review of PET normalization: Striving for count rate uniformity”

Theodorakis L., Loudos G., Prassopoulos V., Kappas C., Tsougos I.,

Georgoulias P.

Nuclear Medicine Communications, 34(11):1033-45, 2013.

11. “Metmorfin reduces the expression of corticotrophin-releasing hormone

and urocortin in the endometrium of healthy women”.


48

Dafopoulos K., Vrekoussis T., Chalvatzas N., Messini C.I., Kalantaridou S.N.,

Georgoulias P., Messinis I.E., Makrigiannakis A.

Fertility and Sterility, 100(5):1405-9, 2013.

12. “Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene

expression in liver cancer cells”.

Befani Ch., Mylonis I., Gkotinakou I.M, Georgoulias P., Hu C.J, Simos G.,

Liakos P.

Int J Biochem Cell Biol, 45(11):2359-68, 2013.

13. “Attenuating activity of the ovary on LH response to GnRH during the

follicular phase of the cycle”.

Dimitraki M., Messini C., Dafopoulos K., Gioka Th., Koutlaki N., Garas A.,

Georgoulias P., Messinis I.E.

Clinical Endocrinology, 80(3):439-43, 2013.

14. “Growth hormone response to submaximal doses of ghrelin remains

unchanged during the follicular phase of the cycle”.

Messini C.I., Dafopoulos K., Malandri M., Georgoulias P., Anifandis G.,

Messinis I.E.

Reprod Biol Endocrinol, 10(11):36, 2013.

15. “Radiolabeling approaches of nanoparticles of (99m) Tc”.

Psimadas D., Bouziotis P., Georgoulias P., Valotassiou V., Tsotakos T.,

Loudos G.

Contrast Media Mol Imag, 8(4): 333-339, 2013.

16. “Clinical significance of serum adipokines levels in lung cancer’’.

Kerenidi T., Lada M., Tsaroucha A., Georgoulias P., Mystridou P.,

Gourgoulianis K.

Medical Oncology, 30(2):1-8, 2013.


49

17. “Fetuin-A is associated with disease severity and exacerbation frequency

in patients with COPD”.

Minas M., Mystiridou P., Georgoulias P., Pournaras S., Kostikas K.,

Gourgoulianis K.I

COPD, 10(1):28-34, 2013.

18. “Metabolism-related cytokine and hormone levels in the serum of

patients with myelodysplastic syndromes”.

Bouronikou E., Georgoulias P., Giannakoulas N., Valotassiou V.,

Palassopoulou M., Vassilopoulos G., Papadoulis N., Matsouka P.

Acta Haematologica, 130(1):27-33, 2013.

19. “Polymeric micelles and vesicles: biological behavior evaluation using

radiolabeling techniques”.

Psimadas D., Oliveira H., Thevenot J., Lecommandoux S., Bouziotis P.,

Varvarigou A.D., Georgoulias P., Loudos G.

Pharm Dev Technolog, 2013 Jan.31 [Epub ahead of print].

20. “The emerging roles of adiponectin in female reproductive system-

associated disorders and pregnancy”.

Angelidis G., Dafopoulos K., Messini C.I, Valotassiou V., Tsikouras P.,

Vrachnis N., Psimadas D., Georgoulias P., Messinis I.E.

Reproductive Sciences, 20(8): 872-881, 2013.

21. “Leptin, Adiponectin, and Ghrelin levels in female patients with asthma

during stable and exacerbation periods”.

Tsaroucha A., Daniil Z., Malli F., Georgoulias P., Minas M., Kostikas K.,

Bargiota A., Zintzaras E., Gourgoulianis K.I

Journal Asthma, 50(2):188-197, 2013.

22. “The progesterone positive feedback effect in women after ovariectomy”.

Zavos A., Dafopoulos K., Messini C.I, Georgoulias P., Verikouki C., Anifandis

G., Garas A., Messinis I.E.


50

Gynecological Endocrinology, 29(3):254-258, 2013.

23. “Optimization of a gamma imaging probe for axillary sentinel lymph

imaging”

Georgiou M., Loudos G., Stratos D., Papadimitroulas P., Liakou P.,

Georgoulias P.

JINST, 7(9): art.no. P09010, 2012.

24. “Depression in patients with cardiovascular disease”.

Mastrogiannis D., Giamouzis G., Dardiotis E., Karagiannis G., Chroub-

Papavaiou A., Kremeti D., Spiliopoulos K., Georgoulias P., Koutsias S.,

Bonotis K., Mantzorou M., Skoularigis J., Hadjigeorgiou G.M., Butler J.,

Tryposkiadis F.

Cardiology Research and Practice, 2012:794762, 2012

25. “Perfusion SPECT studies with mapping of Broadmann areas in

differentiating Alzeheimer’s disease from frontotemporal degeneration

syndromes”.

Valotassiou V.,Papantriantafyllou J., Sifakis N., Tzavara C., Tsougos I.,

Kapsalaki E ., Hadjigeorgiou G., Georgoulias P.

Nuclear Medicine Communications, 33(12): 1267-1276, 2012

26. “Association between epicardial fat thickness and weight homeostasis

hormones in patients with noncachectic heart failure”.

Karayannis G., Giamouzis G., Tziolas N., Georgoulias P., Skoularigis J.,

Mikhailidis D.P., Triposkiadis F.

Angiology, 64(3):173-180, 2012.

27. “Ghrelin: New insights into female reproductive system - Associated

disorders and pregnancy”.

Angelidis G., Dafopoulos K., Messini C.I., Valotassiou V., Georgoulias P.,

Messinis I.E.

Reproductive Sciences, 19(9):903-10, 2012.

http://www.ncbi.nlm.nih.gov/pubmed?term=Karayannis%20G%5BAuthor%5D&cauthor=true&cauthor_uid=22649110

http://www.ncbi.nlm.nih.gov/pubmed?term=Giamouzis%20G%5BAuthor%5D&cauthor=true&cauthor_uid=22649110

http://www.ncbi.nlm.nih.gov/pubmed?term=Tziolas%20N%5BAuthor%5D&cauthor=true&cauthor_uid=22649110

http://www.ncbi.nlm.nih.gov/pubmed?term=Georgoulias%20P%5BAuthor%5D&cauthor=true&cauthor_uid=22649110

http://www.ncbi.nlm.nih.gov/pubmed?term=Skoularigis%20J%5BAuthor%5D&cauthor=true&cauthor_uid=22649110

http://www.ncbi.nlm.nih.gov/pubmed?term=Mikhailidis%20DP%5BAuthor%5D&cauthor=true&cauthor_uid=22649110

http://www.ncbi.nlm.nih.gov/pubmed?term=Triposkiadis%20F%5BAuthor%5D&cauthor=true&cauthor_uid=22649110


51

28. “Molecular nanomedicine towards cancer: (111) In-labeled

nanoparticles”.

Psimadas D., Georgoulias P., Valotassiou V., Loudos G.

J Pharmaceutical Sciences, 101(7):2271-80, 2012.

29. “Elimination half-life of an anti-Mullerian hormone”.

Griesinger G., Dafopoulos K., Buendgen N., Cascorbi I., Georgoulias P., Zavos

A., Messini C.I., Messinis I.E.

J Clinical Endocrinol Metabol, 97(6):2160-3, 2012.

30. “Preliminary evaluation of a 99mΤc labeled hybrid nanoparticle bearing a

Cobalt Ferrite core: in vivo biodistribution”.

Psimadas D., Baldi G., Ravagli C., Bouzioti P., Xanthopoulos S., Franchini M.

C., Georgoulias P., Loudos G.

Journal of Biomedical Nanotechnology, 8(4):575-85, 2012.

31. “Incremental prognostic value of 99mTc- tetrofosmin early post-stress

pulmonary uptake. Determination of the optimal cut-off value”.

Georgoulias P., Tsougos I., Tzavara C., Valotassiou V., Demakopoulos N.


32. “Experimental and simulation studies for the optimization of dedicated

scintimammography cameras’’.

Georgiou M., David S., Loudos G., Tsougos I., Georgoulias P.

Journal of Instrumentation, 7(1), Article number P01011, 2012.

33. “Association of bone mineral density, parameters of bone turnover, and

body composition in patients with Chronic Obstructive Pulmonary

Disease”.

Fountoulis G.A., Minas M., Georgoulias P., Fezoulidis I.V., Gourgoulianis K.I.,

Vlychou M.

Journal of Clinical Densitometry, 15(2):217-23, 2012.


52

34. “SPECT and PET imaging of Meningiomas”.

Valotassiou V., Leondi A., Angelidis G., Psimadas D., Georgoulias P.

The Scientific World Journal, Volume 2012, Article ID 412580,

doi:10.1100/2012/412580

35. “Study of insulin resistance, TNF-a, total antioxidant capacity and lipid

profile in patients with chronic heart failure under exercise”.

Tsarouhas K., Tsitsimpikou C., Haliassos A., Georgoulias P., Koutsioras I.,

Kouretas D., Kogias J., Liosis I., Rentoukas E., Kyriakides Z.

In Vivo, 25(6):1031-7, 2011.

36. “The association of metabolic syndrome with adipose tissue hormones

and insulin resistance in patients with COPD without comorbidities”.

Minas M., Kostikas K., Papaioannou A., Mystridoy P., Karetsi E., Georgoulias

P., Liakos N., Pournaras S., Gourgoulianis K.

COPD, 8(6):414-20, 2011.

37. “Baseline insulin-like growth Factor-I plasma levels, systemic

inflammation, weight loss and clinical outcome in metastatic Non-small

cell lung cancer patients”.

Vlachostergios P.J., Gioulbasanis I., Kamposioras K., Georgoulias P., Baracos

V.E., Ghosh S., Maragouli E., Georgoulias V., Papandreou C.N.

Oncology, 81(2):113-8, 2011.

38. “Mini Nutritional Assessment (MNA) and biochemical markers of

cachexia in metastatic lung cancer patients: interrelations and

associations with prognosis”.

Gioulbasanis I., Georgoulias P.,. Vlachostergios P.J, Baracos V., Ghosh S.,

Giannousi Z., Papandreou C. N., Mavroudis D., Georgoulias V.

Lung Cancer, 74(3):516-20, 2011.

39. “Sequence variations in the FII, FV, F13A1, FGB and PAI-1 genes are

associated with differences in myocardial perfusion”.

http://www.ncbi.nlm.nih.gov/pubmed?term=Study%20of%20Insulin%20Resistance%2C%20TNF-A%2C%20Total%20Antioxidant%20Capacity%20and%20Lipid%20Profile%20in%20Patients%20With%20Chronic%20Heart%20Failure%20Under%20Exercise

http://www.ncbi.nlm.nih.gov/pubmed?term=The%20Association%20of%20Metabolic%20Syndrome%20with%20Adipose%20Tissue%20Hormones%20and%20Insulin%20Resistance%20in%20Patients%20With%20COPD%20Without%20Comorbidities

http://www.ncbi.nlm.nih.gov/pubmed?term=Baseline%20Insulin-Like%20Growth%20Factor-I%20Plasma%20Levels%2C%20Systemic%20Inflammation%2C%20Weight%20Loss%20and%20Clinical%20Outcome%20in%20Metastatic%20Non-Small%20Cell%20Lung%20Cancer%20Patients

http://www.ncbi.nlm.nih.gov/pubmed?term=Mini%20Nutritional%20Assessment%20(MNA)%20and%20Biochemical%20Markers%20of%20Cachexia%20in%20Metastatic%20Lung%20Cancer%20Patients%3A%20Interrelations%20and%20Associations%20With%20Prognosis


53

Satra M., Samara M., Wosniak G., Tzavara C., Kontos A., Valotassiou V.,

Vamvakopoulos NK., Tsougos I., Aleporou-Marinou V., Patrinos GP., Kollia P.,

Georgoulias P.

Pharmacogenomics, 12(2):195-203, 2011.

40. “Does hybrid diagnostic imaging in cardiology have the same

significance as in oncology?”

Georgoulias P., Tsougos I., Valotassiou V., Demakopoulos N.

Eur J Nucl Med Mol Imaging, 38(5):979-81, 2011.

41. “Increased fetuin A levels in Helicobacter Pylori infection: a missing link

between H. Pylori and insulin resistance?”

Manolakis A.C., Tiaka E.K., Kapsoritakis A.N., Georgoulias P., Tsiopoulos F.,

Valotassiou V., Potamianos S.P.

Diabetologia, 54(2):472-4, 2011.

42. “Plasma and aqueous humor levels of ghrelin in open angle glaucoma

patients”.

Katsanos A., Dastiridou A., Georgoulias P., Cholevas P., Kotoula M., Tsironi E.

Clinical and Experimental Ophthalmology, 39(4):324-9, 2011.

43. “Effect of ghrelin and metoclopramide on prolactin secretion in normal

women”.

Messini C.I.,Dafopoulos K., Chalvatzas N., Georgoulias P., Anifandis G.,

Messinis I.E.

Journal of Endocrinological Investigation, 34(4):276-9, 2011.

44. “Current and potential roles of ghrelin in clinical practice’’.

Angelidis G., Valotassiou V., Georgoulias P.

Journal of Endocrinological Investigation, Review, 33(11):823-38, 2010.

45. “Internal radionuclide dosimetry”.

Tsougos I., Georgoulias P., Theodorou K.

http://www.ncbi.nlm.nih.gov/pubmed?term=Effect%20of%20Ghrelin%20and%20Metoclopramide%20on%20Prolactin%20Secretion%20in%20Normal%20Women


54

IHE, 36: 22-23, 2010

46. “Moderate performance of serum S100A12, in distinguishing

inflammatory bowel disease from irritable bowel syndrome”.

Manolakis A.C., Kapsoritakis A.N., Georgoulias P., Tzavara C., Valotassiou V.,

Kapsoritaki A., Potamianos S.P.

BMC Gastroenterology, 10:118, 2010.

47. “Cytolytic T-Cell response against Epstein-Barr virus in lung cancer

patients and healthy subjects”.

Karanikas V., Zamanakou M., Soukou F., Kerenidi T., Tsougos I., Theodorou

K., Georgoulias P., Gourgoulianis K.I., Germenis A.E.

Journal of Experimental and Clinical Cancer Research, 29:64, 2010.

48. “Alzheimer's Disease: SPECT and PET tracers for beta-amyloid imaging”.

Valotassiou V, Archimandritis S, Sifakis N, Papatriantafyllou J, Georgoulias P.

Current Alzheimer Research, 7(6):477-86, 2010.

49. “Myocardial perfusion SPECT imaging in patients after percutaneous

coronary intervention”.

Georgoulias P., Valotassiou V., Tsougos I., Demakopoulos N.

Current Cardiology Reviews, 6(2):98-103, 2010.

50. “Failure of the GnRH antagonist ganirelix to block the positive feedback

effect of exogenous estropatgen in normal women”.

Messinis I.E, Vanakara P., Zavos A., Verikouki C., Georgoulias P.,Dafopoulos

K.


51. “Smoking and AMH levels in women with normal reproductive history”.

Dafopoulos A., Dafopoulos K., Georgoulias P., Galazios G., Limberis V.,

Tsikouras P., Koutlaki N., Maroulis G.

Archives of Gynecology and Obstetrics, 282(2):215-9, 2010.

http://www.ncbi.nlm.nih.gov/pubmed?term=Cytolytic%20T-Cell%20Response%20against%20Epstein-Barr%20Virus%20in%20Lung%20Cancer%20Patients%20and%20Healthy%20Subjects

http://www.ncbi.nlm.nih.gov/pubmed/20455860

http://www.ncbi.nlm.nih.gov/pubmed?term=Failure%20of%20the%20GNRH%20Antagonist%20Ganirelix%20to%20Block%20The%20Positive%20Feedback%20Effect%20of%20Exogenous%20Estrogen%20In%20Normal%20Women


http://www.ncbi.nlm.nih.gov/pubmed?term=Smoking%20and%20AMH%20Levels%20in%20Women%20with%20Normal%20Reproductive%20History%E2%80%9D.


55

52. “Development and evaluation of QSPECT open-source software for the

iterative reconstruction of SPECT images”.

Loudos G.K., Papadimitroulas P., Zotos P., Tsougos I., Georgoulias P.


53. “Patient - specific internal radionuclide dosimetry”.

Tsougos I., Loudos G., Georgoulias P., Theodorou K., Kappas C.

Nuclear Medicine Communications, 31(2):97-106, 2010

54. “Systemic and airway inflammation and the presence of emphysema in

patients with COPD”.

Papaioannou A.I., Mazioti A., Kiropoulos T., Tsilioni I., Koutsokera A., Tanou

K., Nikoulis D.J., Georgoulias P., Zakynthinos E.,Gourgoulianis K.I.,Kostikas K.

Respiratory Medicine, 104(2):275-82, 2010.

55. “Blockage of ghrelin-induced prolactin secretion in women by

bromocriptine”.

Messini C.I., Dafopoulos K., Chalvatzas N., Georgoulias P., Anifandis G.,

Messinis I.E.


56. “Effect of ghrelin and thyrotropin-releasing hormone on prolactin

secretion in normal women”.

Messini C.I., Dafopoulos K., Chalvatzas N., Georgoulias P., Anifandis G.,

Messinis I.E.

Hormone and Metabolic Research, 42(3):204-8, 2010.

57. “Darwinian molecular imaging in nuclear cardiology”.

Georgoulias P., Tsougos I., Valotassiou V.., Samara M., Kollia P.


http://www.ncbi.nlm.nih.gov/pubmed?term=Development%20and%20Evaluation%20of%20QSPECT%20Open-Source%20Software%20for%20the%20Iterative%20Reconstruction%20of%20Spect%20Images

http://www.ncbi.nlm.nih.gov/pubmed?term=Internal%20Radionuclide%20Dosimetry%20tsougos



http://www.ncbi.nlm.nih.gov/pubmed?term=Systemic%20and%20Airway%20Inflammation%20and%20The%20Presence%20of%20Emphysema%20in%20Patients%20With%20COPD%E2%80%9D.



http://www.ncbi.nlm.nih.gov/pubmed?term=Effect%20of%20Ghrelin%20and%20Thyrotropin-Releasing%20Hormone%20on%20Prolactin%20Secretion%20in%20Normal%20Women%E2%80%9D.


56

58. “Long-term prognostic value of early post-stress 99mTc-Tetrofosmin lung

uptake during exercise (SPECT) myocardial perfusion imaging”.

Georgoulias P., Tsougos I., Valotassiou V., Tzavara C., Xaplanteris P.,

Demakopoulos N.

Eur J Nucl Med Mol Imaging, 37(4): 789-98, 2010.

59. “Serotonin and neuron-specific enolase: serum acute and mid-term

levels and their association with post-traumatic depression”.

Wozniak G., Georgoulias P., Iliadis C., Valotasiou V., Papadopoulos G.,

Bagiatis V., Tsougos I., Paterakis K., Fountas K.

Neurosurgery Quarterly, 20: 288-291, 2010.

60. “Impact of ACE and APOE polymorphisms on myocardial perfusion:

correlation with myocardial single photon emission computed

tomographic imaging”.

Georgoulias P., Wozniak G., Samara M., Chiotoglou I., Kontos A., Tzavara C.,

Valotassiou V., Georgitsi M., Aleporou-Marinou V., Patrinos G.P., Kollia P.

Journal of Human Genetics, 54(10):595-602, 2009.

61. “Growth hormone and prolactin response to ghrelin during the normal

menstrual cycle”.

Messini C., Dafopoulos K., Chalvatzas N., Georgoulias P., Messinis I.E.

Clinical Endocrinology (Oxf), 71(3):383-7, 2009.

62. “Effect of ghrelin on gonadotrophin secretion in women during the

menstrual cycle”.

Messini C.I., Dafopoulos K., Chalvatzas N, Georgoulias P., Messinis I.E.

Human Reproduction, 24(4):976-81, 2009.

63. “Heart-rate recovery as a clinical marker of cardiovascular autonomic

dysfunction in diabetic patients”.

Georgoulias P., Valotassiou V., Tsougos I.


http://www.ncbi.nlm.nih.gov/pubmed?term=30.%09%E2%80%9CImpact%20of%20ACE%20and%20APOE%20Polymorphisms%20On%20Myocardial%20Perfusion%3A%20Correlation%20With%20Myocardial%20Single%20Photon%20Emission%20Computed%20Tomographic%20Imaging%E2%80%9D.

http://www.ncbi.nlm.nih.gov/pubmed/19094072?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


http://www.ncbi.nlm.nih.gov/pubmed?term=Growth%20Hormone%20and%20Prolactin%20Response%20to%20Ghrelin%20During%20the%20Normal%20Menstrual%20Cycle%E2%80%9D.%20Growth%20Hormone%20and%20Prolactin%20Response%20to%20Ghrelin%20During%20the%20Normal%20Menstrual%20Cycle%E2%80%9D.%20Growth%20Hormone%20and%20Prolactin%20Response%20to%20Ghrelin%20During%20the%20Normal%20Menstrual%20Cycle%E2%80%9D.%20




57

64. “Drug enhancement of myocardial tracer uptake during myocardial

perfusion imaging”.

Georgoulias P., Valotassiou V., Tsougos I.


65. “A radionuclide dosimetry toolkit based on material specific monte carlo

dose kernels”.

Loudos G., Tsougos I., Boukis S., Karakatsanis N., Georgoulias P., Theodorou

K., Nikita K., Kappas C.


66. “Long-term prognostic value of heart-rate recovery after treadmill testing

in patients with diabetes mellitus”.

Georgoulias P., Demakopoulos N., Valotassiou V., Orfanakis A., Zaganides A.,

Tsougos I., Fezoulidis I.

International Journal of Cardiology, 134(1):67-74, 2009.

67. “Impact of dopamine transporter SPECT imaging using I-123 Ioflupane on

diagnoses of patients with Parkinsonian syndromes”.

Bairactaris C., Demakopoulos N., Tripsianis G., Sioka C., Farmakiotis D.,

Vadikolias K., Heliopoulos I., Georgoulias P., Tsougos I., Papanastasiou I.,

Piperidou C.

Journal of Clinical Neuroscience, 16(2):246-52, 2009.

68. “Evaluation of brain perfusion in specific Broadmann areas in

frontotemporal dementia and Alzheimer disease using automated 3-D

voxel based analysis”.

Valotassiou V., Papatriantafyllou J., Sifakis N., Karageorgiou C., Tsougos I.,

Tzavara Ch., Zerva Ch., Georgoulias P.

JINST, 4: PO5020, 2009.

69. “Incremental prognostic value of 99mTc-Tetrofosmin myocardial SPECT

after percutaneous coronary intervention”.

http://www.ncbi.nlm.nih.gov/pubmed?term=A%20Radionuclide%20Dosimetry%20Toolkit%20Based%20On%20Material%20Specific%20Monte%20Carlo%20Dose%20Kernels

http://www.ncbi.nlm.nih.gov/pubmed?term=Long-Term%20Prognostic%20Value%20of%20Heart-Rate%20Recovery%20After%20Treadmill%20Testing%20In%20Patients%20With%20Diabetes%20Mellitus

http://www.ncbi.nlm.nih.gov/pubmed?term=Impact%20of%20Dopamine%20Transporter%20Spect%20Imaging%20Using%20I-123%20Ioflupane%20on%20Diagnoses%20of%20Patients%20With%20Parkinsonian%20Syndromes


58

Georgoulias P., Tzavara Ch., Demakopoulos N., Giannakou S., Valotassiou V.,

Tsougos I., Xaplanteris P., Fezoulidis I.

Annals of Nuclear Medicine, 22(10):899-909, 2008.

70. “Incidental pathologic extracardiac uptake of 99mTc-Tetrofosmin in

myocardial perfusion imaging”.

Kotsalou I., Georgoulias P., Fourlis S., Zoumboulidis A., Giaslakiotis K.,

Androulaki A. , Chronopoulos P., Dimakopoulos N.

Hellenic Journal of Nuclear Medicine, 11(1):43-5, 2008.

71. “Myocardial perfusion SPECT imaging in patients after coronary

revascularization”.

Georgoulias P., Valotassiou V., Wozniak G., Demakopoulos N., Fezoulidis I.

Vascular Disease Prevention, 5: pp 9-16, 2008.

72. “Radiopharmaceuticals in neurological and psychiatric disorders”.

Valotassiou V., Wozniak G., Sifakis N., Demakopoulos N., Georgoulias P.

Current Clinical Pharmacology, 3(2):99-107, 2008.

73. “Long-term prognostic value of 99mTc-Tetrofosmin myocardial gated-

spect study in asymptomatic patients after percutaneous coronary

intervention”.

Georgoulias P., Demakopoulos N., Tzavara Ch., Giannakou S., Valotassiou V.,

Tsougos I., Xaplanteris P., Fezoulidis I.

Clinical Nuclear Medicine, 33(11):743-7, 2008.

74. “A rare case of myocardial infarction and ischemia in a cannabis-

addicted patient”.

Kotsalou I., Georgoulias P., Karydas I., Fourlis S., Sioka Ch., Zoumboulidis A.,

Demakopoulos N.


http://www.ncbi.nlm.nih.gov/pubmed?term=41.%09%E2%80%9CIncidental%20Pathologic%20Extracardiac%20Uptake%20of%2099mTc-Tetrofosmin%20in%20Myocardial%20Perfusion%20Imaging

http://www.ncbi.nlm.nih.gov/pubmed?term=Radiopharmaceuticals%20in%20Neurological%20and%20Psychiatric%20Disorders%20georgoulias

http://www.ncbi.nlm.nih.gov/pubmed?term=Long-Term%20Prognostic%20Value%20of%2099mTc-Tetrofosmin%20Myocardial%20Gated-SPECT%20Study%20In%20Asymptomatic%20Patients%20after%20Percutaneous%20Coronary%20Intervention

http://www.ncbi.nlm.nih.gov/pubmed?term=A%20Rare%20Case%20of%20Myocardial%20Infarction%20and%20Ischemia%20in%20a%20Cannabis-Addicted%20Patient


59

75. “Evaluation of abnormal heart - rate recovery after exercise testing in

patients with diabetes mellitus: correlation with myocardial SPECT and

chronotropic parameters”.

Georgoulias P., Demakopoulos N., Orfanakis A., Xydis K., Xaplanteris P.,

Vardas P., Fezoulidis I.


76. “SPECT imaging and cerebrovascular disease”.

Valotassiou V., Wozniak G., Sifakis N., Iliadis Ch., Georgoulias P.

Vascular Disease Prevention, 4:165-170, 2007.

77. “Brain perfusion SPECT with 99mTc-ECD and serum neuron-specific

enolase in patients with spontaneous subarachnoid hemorrhage and

clinical vasospasm”.

Iliadis Ch., Apostolopoulos D. J., Papadopoulos G., Tzortzidis F., Wozniak G.,

P. Georgoulias, Kunz A., Panagiotopoulos V., Maraziotis T., Vassilakos P. J.

New Medicine, 4: 90-96, 2006.

78. “Radiosynoviorthesis: indications, side effects”.

Valotassiou V., Wozniak G., Demakopoulos N., Georgoulias P.

Hellenic Journal Nuclear Medicine, 9(3):187-8, 2006.

79. “The role of nuclear medicine in vascular dementia”.

Valotassiou V., Sifakis N., Georgoulias P.

Vascular Disease Prevention, 3: 353-357, 2006.

80. “About mentioning quality of preparation and quality control of

radiopharmaceuticals used in nuclear medicine procedures”.

Wozniak G., Georgoulias P., Archimandritis S., Demakopoulos N., Fezoulidis I.

Hellenic Journal Nuclear Medicine, Jan-Apr; 9(1):41-2, 2006.

http://www.ncbi.nlm.nih.gov/pubmed?term=Evaluation%20of%20Abnormal%20Heart%20-%20Rate%20Recovery%20after%20Exercise%20Testing%20in%20Patients%20with%20Diabetes%20Mellitus%3A%20Correlation%20With%20Myocardial%20SPECT%20and%20Chronotropic%20Parameters

http://www.ncbi.nlm.nih.gov/pubmed?term=About%20Mentioning%20Quality%20of%20Preparation%20and%20Quality%20Control%20of%20Radiopharmaceuticals%20Used%20in%20Nuclear%20Medicine%20Procedures


60

81. “Early post-stress pulmonary uptake of 99mTc Tetrofosmin during

exercise (SPECT) myocardial perfusion imaging: correlation with

haemodynamic, perfusion and function parameters”.

Georgoulias P., Demakopoulos N., Kontos A., Xaplanteris P., Xydis K.,

Fezoulidis I.


82. “The value of 99mTc-ECD SPECT early after the onset of subarachnoid

hemorrhage in predicting symptomatic vasospasm and clinical

outcome”.

Iliadis Ch., Apostolopoulos D. J., Giannakenas C., Spyridonidis T., Wozniak

G., Georgoulias P., Tzortzidis F., Maraziotis T., Vassilakos P. J.

New Medicine, 8: 45-52, 2005.

83. “Stress fracture of the ulnar styloid protuberance”.

Georgoulias P., Demakopoulos N., Fezoulidis I.


84. “A case of false positive myocardial perfusion imaging in a patient with

left bundle branch block”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Mortzos G., Fezoulidis I.


85. “Incidental thallium uptake in bilateral breast lymphoma during

myocardial perfusion scintigram”.

Georgoulias P., Demakopoulos N., Papadaki T., Ioannidis G., Kokkini G.,

Mortzos G.


86. “Abnοrmal heart rate recovery immediately after treadmill testing:

correlation with clinical, exercise testing, and myocardial perfusion

parameters”.

Georgoulias P., Orfanakis A., Demakopoulos N., Xaplanteris P., Mortzos G.,

Vardas P., Karkavitsas N.

http://www.ncbi.nlm.nih.gov/pubmed?term=Early%20Post-Stress%20Pulmonary%20Uptake%20of%2099mTc%20Tetrofosmin%20During%20Exercise%20(SPECT)%20Myocardial%20Perfusion%20Imaging%3A%20Correlation%20With%20Haemodynamic%2C%20Perfusion%20And%20Function%20Parameters

http://www.ncbi.nlm.nih.gov/pubmed?term=Stress%20Fracture%20of%20the%20Ulnar%20Styloid%20Protuberance

http://www.ncbi.nlm.nih.gov/pubmed?term=A%20Case%20of%20False%20Positive%20Myocardial%20Perfusion%20Imaging%20in%20a%20Patient%20With%20Left%20Bundle%20Branch%20Block

http://www.ncbi.nlm.nih.gov/pubmed?term=Incidental%20Thallium%20Uptake%20in%20Bilateral%20Breast%20Lymphoma%20During%20Myocardial%20Perfusion%20Scintigram


61

Journal of Nuclear Cardiology, 10(5):498-505, 2003.

87. “Tc-99m tetrofosmin myocardial spect combined with a modified

exercise protocol in an unusual case of steal phenomenon”.

Georgoulias P., Demakopoulos N., Xaplanteris P., Mortzos G.


88. “Scintigraphy of stress fractures of the sesamoid bones”.

Georgoulias P., Georgiadis I., Dimakopoulos N., Mortzos G.


89. “Scintigraphic detection of experimentally induced thrombi by a new

99mTc decapeptide, RGD derivative”.

Kostopoulos B., Varvarigou A. D., Georgoulias P., Mortzos G.N.,

Dimakopoulos N., Potamianos S.D., Leondiadis L. J., Evangelatos G. P.,

Pelecanou M., Archimandritis S. C.

International Journal of Nuclear Medicine, http://63.96.40.23, 2000.

90. “Tc-99m Tetrofosmin myocardial perfusion scan before and six months

after Percutaneous Transluminal Coronary Angioplasty (P.T.C.A.)”.

Georgoulias P., Demakopoulos N., Kontos A., Xaplanteris P., Thomadakis K.,

Mortzos G., Karkavitsas N.


91. “Myokard-perfusionsszintigraphie mit 99mTc-Tetrofosmin: ein vergleich

mit der koronaren angiographie. (99mTc-Tetrofosmin myocardial

perfusion imaging: a comparison with corοnary angiography)”.

Georgoulias P., Demakopoulos N., Kontos A., Xaplanteris P., Thomadakis K.,

Mortzos G., Karkavitsas N.

NuklearMedizin, 35(5):153-5, 1996.

AWARDS - DISTINCTIONS

http://www.ncbi.nlm.nih.gov/pubmed?term=Abn%CE%BFrmal%20Heart%20Rate%20Recovery%20Immediately%20After%20Treadmill%20Testing%3A%20Correlation%20With%20Clinical%2C%20Exercise%20Testing%2C%20and%20Myocardial%20Perfusion%20Parameters

http://www.ncbi.nlm.nih.gov/pubmed?term=%E2%80%9D.Tc-99m%20Tetrofosmin%20Myocardial%20Spect%20Combined%20With%20A%20Modified%20Exercise%20Protocol%20in%20an%20Unusual%20Case%20of%20Steal%20Phenomen

http://63.96.40.23/

http://www.ncbi.nlm.nih.gov/pubmed?term=Tc-99m%20Tetrofosmin%20Myocardial%20Perfusion%20Scan%20Before%20and%20Six%20Months%20after%20Percutaneous%20Transluminal%20Coronary%20Angioplasty%20(P.T.C.A.

http://www.ncbi.nlm.nih.gov/pubmed?term=Myokard-Perfusionsszintigraphie%20mit%2099mTc-Tetrofosmin%3A%20Ein%20Vergleich%20Mit%20Der%20Koronaren%20Angiographie.%2099mTc-Tetrofosmin%20Myocardial%20Perfusion%20Imaging%3A%20A%20Comparison%20With%20Cor%CE%BFnary%20Angiography


62

1. The presentation entitled “Effects of long-term treatment with non-

interventional mechanical ventilation on homeostasis model assessment

(HOMA), in patients with stable chronic obstructive pulmonary disease

and chronic hypercapnic respiratory failure”, Dimoulis A., Pastaka Ch.,

Tsolaki B., Tsilioni E., Pournaras S., Liakos N., Georgoulias P., Gourgoulianis

K., was awarded as one of the most important presentations in the 23th

Panhellenic Congress of Pneumonology, Athens, November 5th-8th, 2014.

2. The book chapter entitled “Clinical Significance of Tetrofosmin

Extracardiac Uptake During Myocardial Perfusion Imaging”, P.

Georgoulias, V. Valotassiou, I. Tsougos, G. Agelides, N. Demakopoulos,

("Coronary Angiography / Book 2", ISBN 979-953-307-235-6, Intech Open

Access Publisher, 2011) has been accessed so far 3787 times.

3. The book chapter entitled “Clinical Use of SPECT and PET Molecular

Imaging in Alzheimer’s Disease” (Valotassiou V., Sifakis N.,

Papatriantafyllou J., Angelidis G. and Georgoulias P.), (The Clinical Spectrum

of Alzheimer’s Disease - The Change Towards Comprehensive Diagnostic and

Therapeutic Strategies, ISBN 978-953-307-993-6, Intech Open Acess

Publisher, 2011) has been accessed so far 2816 times.

4. The presentation entitled “99mTc-HMPAO-SPECT with mapping of

Broadmann areas in the differential diagnosis of Frontotemporal

Dementia from Alzheimer’s Disease”, Valotassiou V., Papatriantafyllou I.,

Sifakis N., Tzavara Ch., Tsougos I., Psimadas D., Kournouti M., Kapsalaki E.,

Chadjigeorgiou G., Georgoulias P., was awarded as one of the most important

Presentations in the 11th Panhellenic Conference of Nuclear Medicine, Athens,

March 30th- April 1st, 2012.

5. The presentation entitled: “Evaluation of perfusion in Cognitive-Semantic

Dementia and Alzheimer’s Disease using 99mTc-HMPAO-SPECT and

mapping of Broadmann areas”, Valotassiou V., Papatriantafyllou I., Sifakis

N., Tzavara Ch., Tsougos I., Psimadas D., Ziaka A., Kapsalaki E.

Chadjigeorgiou G., Georgoulias P., was awarded as one of the most important

Presentations in the 11th Panhellenic Conference of Nuclear Medicine, Athens,

March 30th- April 1st, 2012.


63

6. The paper entitled “Does hybrid diagnostic imaging in cardiology have the

same significance as in oncology?”, Georgoulias P., Tsougos I.,

Valotassiou V., Demakopoulos N., (Eur J Nucl Med Mol Imaging, May; 38(5):

979-81, 2011), was included as one of the most interesting manuscripts in

Current Readings in Nuclear Medicine, Clinical Nuclear Medicine, Volume 36,

Number 7, July 2011.

7. The paper entitled “Development and evaluation of QSPECT open-source

software for the iterative reconstruction of SPECT images”, Loudos G.K.,

Papadimitroulas P., Zotos P., Tsougos I., Georgoulias P., (Nuclear Medicine

Communications, Jun; 31(6):558-66, 2010), was included as one of the most

interesting manuscripts in Current Readings in Nuclear Medicine, Clinical

Nuclear Medicine, Volume 35, Number 8, August 2010.

8. The paper entitled “Patient-specific internal radionuclide dosimetry”,

Tsougos I., Loudos G., Georgoulias P., Theodorou K., Kappas C., (Nuclear

Medicine Communications, Feb; 31(2):97-106, 2010) was included as one of

the most interesting manuscripts in Current Readings in Nuclear Medicine,

Clinical Nuclear Medicine, Volume 35, Number 4, April 2010.

9. The paper entitled “The association of metabolic syndrome with adipose

tissue hormones and insulin resistance in patients with COPD without

comorbidities”, Minas M., Kostikas K., Papaioannou A., Mystridoy P., Karetsi

E., Georgoulias P., Liakos N., Pournaras S., Gourgoulianis K., (COPD, Dec;

8(6):414-20, 2011) was commented in an Editorial Letter entitled “Metabolic

Syndrome and Systemic Inflammation in COPD’’, (COPD; 8: 395-396,

2011), (E. Kern), published in the same issue.

10. 2nd award of Presentations for the presentation entitled “Epidemiological

study for depression in patients with obesity’’, Kontoriga A., Mouzas O.,

Charavgi N., Georgoulias P., Vankova M., Tsakalaki M.

2nd Panhellenic Psychiatric Conference, June 4 – 6, Killini, 2010.

11. Award for the study entitled “Experimental and simulation studies for the

optimization of dedicated scintimammography cameras”, Georgiou M.,

Loudos G., David S., Georgoulias P., (E J Nucl Med Mol.Imaging 2010; Suppl

2, S352), which was presented in the 23th Annual Congress of the European

http://www.ncbi.nlm.nih.gov/pubmed?term=Development%20and%20Evaluation%20of%20QSPECT%20Open-Source%20Software%20for%20the%20Iterative%20Reconstruction%20of%20Spect%20Images

http://www.ncbi.nlm.nih.gov/pubmed?term=The%20Association%20of%20Metabolic%20Syndrome%20with%20Adipose%20Tissue%20Hormones%20and%20Insulin%20Resistance%20in%20Patients%20With%20COPD%20Without%20Comorbidities


64

Association of Nuclear Medicine, Vienna, Austria, October, 2010, as one of the

best in the conference.

12. Award for the study entitled “Impact of FXIIIA1, FII, FV, FGB AND PAI1

polymorphisms on myocardial perfusion: correlation with myocardial

Single Photon Emission Computed tomographic imaging”, Satra M.,

Samara M., Wozniak G., Kontos A., Valotassiou V., Tsougos I., Kollia P.,

Georgoulias P., (E J Nucl Med Mol.Imaging 2010; Suppl 2, S352), which was

presented in the 23th Annual Congress of the European Association of

Nuclear Medicine, Vienna, Austria, October, 2010, as one of the best in the

conference.

13. Award for the study entitled «Fetuin as a differential diagnostic marker in

patients with haemorragic diarrhea: Ulcear, ischaemic colitis and large

intenstine tumors”, Manolakis A., Kapsoritakis A., Georgoulias P.,

Christodoulidis G., Tiaka E., Tsimperidis A., Tsiopoulos F., Oikonomou K.,

Magaliou N., Andritsopoulos K., Valotassiou V., Potamianos S., which was

presented in the 30th Panhellenic Conference of Gastroenterology, Athens,

2010.

14. “Dimitris Manios’’ award for the study entitled “Correlation of new

polymorphisms CER1 gene with metabolic markers in osteporotic

fractures”, Koromila Th., Kollia P., Georgoulias P., Samara S., Chasanidis

Ch., Aleporou M., Ntailiana Z. which was presented in the 66th Panhellenic

Conference of Orthopeadics, Athens, 2010.

15. “Alexandros Kalos” award for the study entitled «Study of CER1 gene-

biochemical markers and correlation with osteoporosis”, Koromila

Th.,Kollia P., Georgoulias P., Samara S., Chasanidis Ch., Aleporou M.,

Ntailiana Z., which was presented in 18th Panhellenic Conference of the

Hellenic Society of Bones Metabolism Studies (Ε.Ε.Μ.Μ.Ο), Athens, 2010.

16. The poster entitled “Inflammatory bowel disease – induced changes in

circulating levels of α2-Heremans-Schmid glycoprotein (Fetuin A)”,

Manolakis A. C., Kapsoritakis A. N., Georgoulias P., Tiaka E. K, Oikonomou

K., Christodoulidis G., Valotassiou V. J., Potamianos S. P., was announced as

“Highly Commented” in the 5th European Cancer Organization Congress

(ECCO), Prague, 2010.


65

17. The paper entitled “Incremental prognostic value of 99mTc-tetrofosmin

myocardial SPECT after percutaneous coronary intervention.”,

Georgoulias P., Tzavara Ch., Demakopoulos N., Giannakou S., Valotassiou

V., Tsougos I., Xaplanteris P., Fezoulidis I., (Annals of Nuclear Medicine, 2008;

22: 899-909), was included as one of the most interesting manuscripts in the

Current Readings in Nuclear Medicine, Clinical Nuclear Medicine, Volume 34,

Number 4, April 2009

18. The paper entitled “Drug enhancement of myocardial tracer uptake during

myocardial perfusion imaging”, Georgoulias P., Valotassiou V., Tsougos I.,

(European Journal of Nuclear Medicine and Molecular Imaging 2009; 36: 160-

161), was included as one of the most interesting manuscripts in the Current

Readings in Nuclear Medicine, Clinical Nuclear Medicine, Clinical Nuclear

Medicine, Volume 34, Number 3, March 2009

19. The paper entitled “Evaluation of abnormal heart-rate recovery after

exercise testing in patients with diabetes mellitus: Correlation with

myocardial SPECT and chronotropic parameters”, Georgoulias P.,

Demakopoulos N., Orfanakis A., Xydis K., Xaplanteris P., Vardas P.,

Fezoulidis I., (Nuclear Medicine Communications 2007; 28: 165-171), was

included as one of the most interesting manuscripts in the Current Readings in

Nuclear Medicine, Clinical Nuclear Medicine, Volume 32, Number 5, May 2007.

20. The paper entitled “Early post-stress pulmonary uptake of 99mTc

tetrofosmin during exercise (SPECT) myocardial perfusion imaging:

correlation with haemodynamic, perfusion and function parameters”,

Georgoulias P., Demakopoulos N., Kontos A., Xaplanteris P., Xydis K.,

Fezoulidis I., (Nuclear Medicine Communications 2006; 27: 119-126), was

included as one of the most interesting manuscripts in the Current Readings in

Nuclear Medicine, Clinical Nuclear Medicine, Volume 31, Number 4, April

2006.

21. The paper entitled “Abnοrmal heart rate recovery immediately after

treadmill testing: correlation with clinical, exercise testing, and

myocardial perfusion parameters”, Georgoulias P., Orfanakis A.,

Demakopoulos N., Xaplanteris P., Mortzos G., Vardas P., Karkavitsas N.,

(Journal of Nuclear Cardiology 2003; 10: 498-505), was included as one of the


66

most interesting manuscripts in the Current Readings in Nuclear Medicine,

Clinical Nuclear Medicine, Volume 30, Number 1, January 2004.

22. The paper entitled “99mTc-Τetrofosmin myocardial perfusion imaging: a

comparison with corοnary angiography”, Georgoulias P., Demakopoulos

N., Kontos A., Xaplanteris P., Thomadakis K., Mortzos G., Karkavitsas N.,

(NuklearMedizin 1996; 35: 153-155), was included as one of the most

interesting manuscripts in the Current Readings in Nuclear Medicine, Clinical

Nuclear Medicine, Volume 22, Number 4, April 1997.


67

SUMMARY OF Ph.D.THESIS

Since the first application of the percutaneous transluminal coronary angioplasty

in 1977, the spread of the method has been vey rapid.

The aim of the present study was to assess the change in myocardial perfusion

and mobility in patients with coronary artery disease subjected to angioplasty, by

using myocardial SPECT imaging (with 201Tl or 99mTc-tetrofosmin) both at stress and

rest radioisotopic ventriculography (at rest and after isometric exercise). Forty-one

patients (38 men and 3 women) of age ranging from 35 to 70 years were studied.

Twenty-one patients had one-vessel disease and were subjected to successful

revascularization of the stenosed artery, 16 had two-vessel disease and were

subjected to one-stenosed vessel angioplasty and 4 patients had 3-vessel disease.

From the patients were subjected to one-vessel revascularization and one was

subjected to 2-vessel re-opening. Sixteen of the patients had mentioned myocardial

infarction in their history.

All the patients were examined, the month prior to angioplasty, by using

myocardial tomographic imaging (29 with 201Tl and 12 99mTc-tetrofosmin), both at

stress and rest and radioisotopic ventriculography-MUGA-(at rest and after isometric

exercise). An angiographic checking was done to all patients prior to intervention.

The function of the left ventricle, using radioisotopic ventriculography (at rest and

after isometric exercise) was assessed 4±1 weeks after revascularization. Besides,

a myocardial SPECT using 201Tl or 99mTc-tetrofosmin, at stress and rest,

respectively, as well as radioisotopic ventriculography (at rest and after isometric

exercise) 6±1 months after angioplasty, was performed. One patient who did not any

improvement of the total as well as regional wall motion of the left ventricle in the

month’s checking, was sublected to myocardial SPECT imaging two months after

the revascularization. Five patients who did not show improvement in the ejection

fraction and the myocardial imaging 6 months after angioplasty, were again subjects

to coronary angiography 7±1 months after the intervention. One patient, despite the

improvement of the perfusion and the function of the left ventricle, as it was

assessed by the above tests, was still complaining for precardiac distress and, for


68

this reason, he was subjected to coronary angiographic checking seven months

after the intervention.

The vast majority of the patients showed an improvement both in the

symptomatology and in the efficiency at the stress testing, following angioplasty. We

found a strong correlation between the findings of the tomographic scan of

myocardium with 201Tl and the coronary angiography prior to angioplasty with

sensitivity, specificity, positive predictive value and negative predictive value: for the

left arterior descending artery 96%, 75%, 96% 75%, for the left circumflex artery

60%, 100%, 100%, 79% and for the right coronary artery 100%, 70.5%, 70.5%, and

100%. Satisfactory were also the findings with analogous study conducted by us in

52 patients that compared the results of the tomographic myocardial scan with

99mTc-tetrofosmin with the coronary angiographic checking with sensitivity, specificity,

positive predictive value and negative predictive value: for the left anterior

descending artery 91.1%, 83.3%, 88.5%, 83.3%, for the left circumflex artery 72.2%,

88.2%, 76.4%, 85.7% and for the right coronary artery 90.6%, 80%, 87.8% and

84.2%. Twenty-five (86.2%) of the 29 patients who were examined with 201Tl and 11

(91.6%) of the 12 patients who were checked with 99mTc-tetrofosmin showed

improvement of the myocardial image, at about 6 months after the intervention,

whereas the rest (5 patients) were subjected again to coronary angiography which

confirmed the existence of restenosis. All the patiens showed improvement in the

total and regional wall motion of the left ventricle, 1 month after the re-perfusion,

except one to whom it was proven the existence of re-stenosis 6 months after the

intervention. The improvement in the general and regional ejection fraction

remained 6 months following angioplasty to most patients, accordingly to the

myocardial scan improvement. Finally, there was a significant improvement to the

“cardiopulmonary index’’ (in those patients who were examined with 201Tl) as well as

of PER and PFR indices, of the curve indicating volume change of the left ventricle.

The vast majority of the patients subjected to angioplasty, display significant

improvement not only to perfusion but also to the function of the left ventricle

myocardium. The radioisotopic techniques (tomographic scan with 201Tl and 99mTc-

tetrofosmin and radioisotopic ventriculography), consist important and non-invasive

methods for assessing and monitoring of the aforementioned patients.

curriculum vitae panagiotis an.georgoulias, m.d., phcurriculum vitae p. an. georgoulias (assoc....

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