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August 2015

CURRICULUM VITAE Robert M. Jacobs, DVM, PhD Diplomate ACVP Professor Emeritus Department of Pathobiology Ontario Veterinary College University of Guelph Guelph, Ontario Canada N1G 2W1 Phone 519-8244120, ext 54827 Mobile 519-8377348 Email rjacobs@uoguelph.ca

Degrees

Specialist in Veterinary Pathology, Canadian Veterinary Medical Association, 1982 Diplomate, Board Certification, American College of Veterinary Pathologists, 1981 PhD, Experimental Pathology, Department of Pathology, University of Guelph, Ontario, 1980 DVM, Veterinary Medicine, University of Guelph, Ontario, 1976

BSc, General Science, University of Toronto, 1972 Employment

Professor Emeritus, Retired Sep 2016 Chair, Department of Pathobiology, Ontario Veterinary College, University of Guelph, Sep 2008 to Aug 2013 – see below for details Assistant Dean Research and Graduate Affairs, Ontario Veterinary College, University of Guelph, Jan 2005 to May 2008 – see below for details

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Full Professor and member of the Graduate Faculty, Department of Pathology/Pathobiology, Ontario Veterinary College, University of Guelph, May 1994 to present Associate Professor and member of the Graduate Faculty, Department of Pathology, Ontario Veterinary College, University of Guelph, Sep 1985 to Apr 1994 Assistant Professor and member of the Graduate Faculty, Department of Pathology, College of Veterinary Medicine, The Ohio State University, Jan 1980 to Sep1985

Honours

1999, Teacher of the Year, Students of the Canadian Veterinary Medical Association

1999, Distinguished Teacher Award, Pfizer/Carl J. Norden

1985 – 88, Adjunct faculty, The Ohio State University, College of Veterinary Medicine

1978, Commonwealth Bureau of Animal Health Prize 1978, Charles Louis Davis Foundation Scholarship in Veterinary Pathology

1976 – 80, Medical Research Council Fellowship

Memberships

International Society for Animal Clinical Biochemistry Canadian Veterinary Medical Association

Licensed Veterinarian, College of Veterinarians of Ontario

American Society for Veterinary Clinical Pathology International Academy of Pathology American College of Veterinary Pathologists Veterinary Cancer Society

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Sigma Xi Conference of Research Workers in Animal Disease

Details - Chair, Department of Pathobiology (Sep 2008 to Aug 2013)

Represent the Department within the College and broader University in all research, teaching, and service activities, 26 faculty, 4 administrative staff, 20 research/technical staff, 70 graduate students in Diploma, MSc, DVSc, and PhD programs, approximately $4 million annual research funding, annual departmental budget outside of research including salaries approximately $12 million. Meet with all faculty members annually regarding promotion and tenure and lead the departmental meetings making recommendations to the college committee. Internal review of the department’s undergraduate teaching program. Successful review. External review of the department’s graduate & research programs by the Ontario Council of Graduate Studies. Hosting of external reviewers. Very complimentary review.

Completed the design phase of the new Pathobiology AHL building ($65 million) started by the previous Chair and orchestrated the implementation phase (approximately 1 year). Worked with faculty and staff to choose, order and put in place new equipment (approximately $2 million). Lead the move and settling-in of approximately 400 individuals to the new building. Took an additional 2 years of effort to work with engineers, contractors, and architects to overcome building deficiencies. Worked closely with the AHL Director to resolve many building issues. Conceived and initiated Pathobiology’s Poultry Health Research Network (PHRN). Transitioned the leadership of this program to Dr. S. Sharif, a prominent poultry immunologist/virologist. The PHRN is a College initiative and has start-up funds to further build the program. Wrote the text for departmental programs for the Program Prioritization Process (PPP). University-wide program aimed at rating academic and non-academic programs/units. Member College Curriculum Review Committee

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Produce research, graduate student, teaching reports for the College and University. Recruited and hired 4 new faculty members. Member of Dean’s Council.

Details - Assistant Dean Research and Graduate Affairs (Jan 2005 – May 2008)

Represent the College in all research matters including animal care, approximately 100 faculty, research support staff, and up to 300 graduate students in Diploma, MSc, DVSc and PhD programs, approximately $15 million annual research funding

Liaise with Dean, other College Assistant Deans, Department Chairs, and Department Graduate Co-ordinators Administer College-wide interdepartmental Doctor of Veterinary Science (DVSc) graduate program Attend DVSc qualifying examinations, read theses and attend final defenses (approximately 40/year), Established a more uniform program across college departments and standardized the assessment Administer the College Graduate Fellowship program Administer Summer Leadership and Research Program (SLRP) in conjunction with Merck Merial Scholars Program Schofield Lecture in conjunction with Graduate Student Research Day

Chappel Lecture

Manage annual or twice annual Pet Trust competition for research funding. Doubled the annual amount of research funding available to researchers through Pet Trust.

Chair Magnetic Resonance Imaging Management Committee

Member Laboratory for Translational Biomedical Discovery Management Committee

Member Research Services Committee under the direction of Associate Vice President Research, biweekly meetings

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Member Advanced Analysis Centre Management Committee Member Equine Guelph Board

Pet Trust Board Member Member of Dean’s Council Produce research summaries for Pet Trust advancement

Produce Ontario Council for Graduate Studies report, host external reviewers, formulation College response resulting in a strong approval for the continuation of the DVSc program

Participate on faculty search committees, attend seminars, meet with candidates

Read OR-5 and review grants, signatures Attend University/OMAFRA executive meetings Annual Veterinary Continuing Education Program reports

Liaise and report generation, projections for Graduate Program Services and Graduate Studies Dean used for reporting research activity to governmental agencies and maintaining graduate funding going forward Administer programs for summer studentships in conjunction with URAs and USRAs

Graduate Students (degree, thesis title, year completed, employment) for which I was Graduate Advisor or Co-Advisor

1. Michal Neta (PhD). Pathogenesis of canine histiocytic proliferative disease. 2011 (diagnostic pathologist, private sector, Brighton, UK)

2. Gerardo Quiroz-Rocha (DVSc). Disease prediction based upon blood biochemical analysis of dairy cattle in the transition period. 2006 (university professor, Mexico City)

3. Masako Mizuno (Diploma). Clinical Pathology. Analysis of the cytological

data from adult dogs with chest masses. 2004 (veterinary practice, private sector, Vancouver, BC)

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4. Sonya Keller (DVSc). Pathogenesis of type 2 BVDV infection in cattle. 2005 (diagnostic pathologist, private sector, Markham, Ontario)

5. Marianne Van Den Heuvel (PhD). Regulation of expression of bovine

leukemia virus. 2002 (post-doctoral fellow, research scientist, London, Ontario)

6. Paula Krimer (DVSc). Assessment of relevance of various isoenzymes of

alkaline phosphatase in dogs. 2001 (institutional diagnostic pathologist, Georgia, US)

7. Darren Wood (DVSc). Pathogenesis of type 2 BVDV infections in cattle.

2000 (university professor, Ontario)

8. Jatain Sondhi (Diploma). Clinical Pathology. Retrospective analysis of polyarthritis in the dog. 2000 (veterinary practice, private sector, California, US)

9. Oliver Trochta (MSc). Immunohistochemical and gene expression of

basic-FGF in canine hemangiosarcoma. 1998 (chiropractor, private sector, Ontario)

10. Einar Jorundsson (Diploma). Clinical Pathology. Special staining and

morphometry in neoplasia. 1997 (university professor, Norway/Iceland)

11. Krystyna Grodecki (DVSc). Hereditary Nephritis – Biochemistry. 1995 (diagnostic pathologist, private sector, Ontario)

12. Malcolm Gains (DVSc). Hereditary Nephritis – Morphometry. 1994

(diagnostic pathologist, private sector, Quebec)

13. Dorothee Bienzle (MSc). Retorviral Vector – Bone Marrow. 1992 (university professor, Ontario)

14. Helen Smith (MSc). Bovine immunodeficiency virus in sheep. 1992

(research scientist, private sector, Iowa)

15. Judith Taylor (DVSc). Factors affecting bovine leukemia virus expression. 1992 (diagnostic pathologist, private sector, Ontario)

16. Mary Schnurr (MSc). Karyotypic analysis of bovine lymphomas. 1992

(animal care technician, Ontario)

17. William Vernau (DVSc). Immunophenotypes and morphometry in bovine lymphomas. 1991 (university professor, California)

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18. Barbara Kalow (DVSc). Lymphocyte calcium metabolism. 1990

19. Roger Ellison (MSc). Alkaline phosphatase isoenzymes in the horse. 1988 (diagnostic pathologist, private sector, New Zealand)

20. Catherine Rae (Diploma). Clinical Pathology. 1988 (veterinary specialist,

private sector, Ontario)

21. Robert Murtaugh (MSc). Canine isoamylases. 1985 (internal medicine specialist and corporate veterinary practice management, US)

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Teaching - Contact Hours

Contact Hours

Academic

Year

Number of Courses

Lecture Lab Clinical Grad –

Diagnostic Pathology

Total

1985-86

8

51

56

191

298

1986-87 8 26 379 189 594

1987-88 8 27 79 189 298

1988-89 8 14 96 108 218

1989-90 9 14 36 108 158

1990-91 9 14 36 108 158

1991-92 9 14 36 108 158

1992-93 9 14 36 108 158

1993-94 9 14 36 54 104

1994-95 8 72 44 367 483

1995-96 12 139 201 167 507

1996-97 12 92 52 197 341

1997-98 13 122 62 206 390

1998-99 8 27 166 57 250 1999-00 8 64 156 58 278 2000-01 8 18 119 325 462 2001-02 2002-04 2004-06 2006-07 2007-08 2008-09 2009-10 2010-12 2012-13 2013-14 2014-15

6 10 7 1 5 5 5 6 5 4 3

9 148

6 90 6 4 2

108 8

23 0

179 112 107

0 32 28 64 16

120 8 0

146 119 115

0 180 180 100 360 114 900 210

334 379 228 90

218 223 168 484 242 931 210

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Undergraduate Course Participation Principles of Disease Systems Pathology Health Management – Phase 4 Rotation Graduate Course Participation Applied Clinical Pathology I Applied Clinical Pathology II Applied Clinical Pathology III Special Topics in Pathobiology Clinical Pathology II Clinical Pathology I Pathophysiology in Small Animal Surgery Mechanisms of Disease

Research Grants

Years Source Title PI (if not R. Jacobs)

Am’t/Yr

2011/12 2002/06

Pet Trust OMAFRA, Livestock Research Fund

Immunofluorescent and confocal analyses of granule polarization In canine histiocytic diseases research including operating, technical support, animals & per diem, Use of BVDV isolates of known virulence in studies aimed at evaluating their potential as vaccines and to elucidate the mechanisms causing characteristic hematological changes

14,000

62,000

1998/03 Canadian Institute of

research including operating, technical support, animals & per

P. Thorner 112,381

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Health Research

diem, Gene therapy in X-linked Alports Syndrome

1998/99 OMAFRA, Livestock Research Fund

research including operating, technical support, animals & per diem, Pathogenesis of Type II BVDV infections

57,000

1997 /98 Pet Trust Search for retroviruses in canine granulomatous meningoencephalitis

5,000

1997/98 Pet Trust and Boehringer Mannheim Corp.

Interferences caused by lipemia, hemoglobinemia, and bilirubinemia on 18 serum analytes determined on the Hitachi 911 automated chemistry analyzer in four animal species

7,500

1997/99 Dairy Farmers of Canada and NSERC

Characterization of virulence factors in Type II BVDV by the formation of chimeras

60,000

1996/97

OMAFRA

Prevalence, determined by serology and proviral detection, of BIV in bulls

5,000

1996/97

OMAFRA

Characterization of plasma factors blocking the expression of bovine leukemia virus

5,000

1996/97

Pet Trust

Establishment of canine hemangiosarcoma cell lines and expression of FGF receptor

6,500

1995/98

Medical Res. Council of Canada

Gene therapy in X-linked canine hereditary nephritis

P. Thorner

65,000

1995/96

OMAFRA

BIV in bull studs in Ontario

4,600

1995/96

OMAFRA

Plasma blocking factor in cattle

4,600

1994/95

Hills Pet Nutrition, Inc

Support for canine colony for hereditary nephritis studies

26,000

1994/96

Canadian Association of Animal

Prevalence studies of BIV in dairy bulls

4,000

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Breeders 1994/98

NSERC Operating

Characterization of plasma blocking factor

20,000

1993/94

NSERC Operating

Interaction of Bovine Retroviruses in the Production of Disease

20,000

1992/93

Ontario Milk Marketing Board

Development and validation of a herd level BLV testing program

D. Kelton

10,000

1992/93

Ontario Milk Marketing Board

Identification of factors important in resistance to the development of chronic S. aureus mastitis in dairy cows

K. Leslie

8,400

1992/93

Pet Trust

Effects of an ACE-inhibitor on the development of renal failure

3,500

1992/93

Pet Trust

A pilot study attempting to demonstrate retroviral sequences in canine lymphomas using PCR with primers crossreactive with known mammalian retroviruses

5,300

1991/94

Medical Res. Council of Canada

Renal disease in Samoyed dogs as a model for human x-linked hereditary nephritis

R. Baumal

278,513

1991/92

Pet Trust

Effects of hypotension on the development of Samoyed hereditary glomerulopathy

5,000

1989/92 NSERC Strategic, Livestock Research Fund

Pathogenesis of bovine immunodeficiency-like virus in a sheep model

60,000

1989/90

Univ. of Guelph Research Enhancement Fund

Development of a serological test and DNA probe for the detection of bovine immunodeficiency-like virus-infected cattle

30,000

1988/89

Ontario Milk

Development of a serological test

5,000

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Marketing Board, Dean's Award

for the detection of bovine immunodeficiency-like virus-infected cattle

1988/89

Medical Res. Council of Canada, Dean’s Discretionary Funds

Renal disposition of canine amylase, lipase, and lysozyme.

3,400

1987/90

NSERC Operating

Prevalence and pathogenetic significance of genetic variants of Bovine Leukemia Virus.

72,900

1987/90

Ontario Ministry of Agriculture and Food

Host target cell characteristics and viral genetic variation in the pathogenesis of Bovine Leukemia Virus-Associated syndromes.

450,000

1987/88

Univ. of Guelph Research Excellence

Restriction endonuclease analysis of Bovine Leukemia Virus genetic variants.

26,000

1987/88

Agriculture Can. Dean's Discretionary Fund

Isoelectric focusing of alkaline phosphatase from equine tissues and sera.

4,000

1986/87

Canadian Veterinary Research Trust Fund

Canine isoamylases in the discrimination of pancreatic and non-pancreatic diseases.

8,500

1986/87

Univ of Guelph Research Board

Pancreatic specificity of canine isoamylases.

10,000

1986/87

American Animal Hospital Association

A comparative study of efficacy and deleterious effects associated with various immunosuppressive therapies for primary Coombs positive anemias

US 10,000

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1986/87

Univ. of Guelph President's Special Fund

High performance liquid chromatography system for Departments of Pathology and VMI

10,000

1985/86

American Animal Hospital Association

A micro-ELISA procedure for platelet associated IgG.

US 9,900

1985/86

Ohio State Univ. Canine Res. Fund

Serum calcium fractions in normal dogs and dogs with renal failure.

D. Chew

US 7,414

1985/86

Ohio State Univ. Canine Res. Fund

In vitro staining of canine parathyroid gland & pancreatic tissues with intravenous methylene blue.

D. Smeak

US 7,489

1985/86

Canine Res. Fund

Studies on canine isoamylases: 1. Proof of specificity of isoamylase-3 for canine pancreas, 2. Heat lability of canine isoamylase.

US 6,720

1984/85

Canine Res. Fund

Lithium as a myeloprotective agent during anticancer chemotherapy in the normal dog.

C. Couto

US 7,140

1984/85

Glenn Barber Res. Foundation

Isoamylase changes in the dog associated with diseases other then pancreatitis.

US 5,600

1984/85

Univ. Seed Grant

The distribution and binding affinity of lectins in normal and neoplastic tissues from dogs.

US 5,000

1984

Equine Res. Fund

Transient iron deficiency in foals and RBC-G6PD as an index of erythroid turnover in foals.

C. Kohn

US 15,000

1983/84

Canine Res. Fund

Detection of retrovirus in canine lymphoma.

G. Kociba

US 7,500

1982/83

Equine Res. Fund

Platelet aggregation in the horse. Effects of non-steroidal anti-inflammatory drugs.

US 5,000

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1982/83

Canine Res. Fund

Experimental pancreatitis and isoamylase changes in the dog.

US 7,500

1982/83

Canine Res. Fund

Isoamylases in clinically normal and diseased dogs.

US 2,000

PUBLICATIONS: Life-time summary (count) according to the following categories: - Books and book chapters ................................................................................. 35 -Letters, Notes and Short Communications in Refereed Journals……………….12 - Papers in refereed journal .............................................................................. 133 - Papers in refereed conference proceedings. ...................................................... 1 - Abstracts and/or papers read ........................................................................... 37 - Invited presentations at professional meetings and continuing education….55

Books and book chapters

1. Valli, V. E. O. and Jacobs, R. M. Structure, Function, and Disorders of Lymphoid Tissue. In Schalm’s Veterinary Hematology, 6th edition, Lea & Febiger. pp 267 – 375. 2010

2. Jacobs, R. M. Chapter reviewer: Normal and benign reactive

hematopoietic tissues. In Veterinary Comparative Hematopathology by V. E. Valli. Blackwell Publishing. 2007.

3. Meuten D, Thomson K, Jacobs RM. Urinary tract tumors of domestic

animals . Armed Forces Institute Pathology in cooperation with the American Registry of Pathology and The World Health Organization Collaborating Center for Comparative Oncology. 2004.

4. Valli, V. E., R. M. Jacobs, A. L. Parodi, W. Vernau. Histological

classification of hematopoietic tumors of domestic animals. Armed Forces Institute of Pathology in cooperation with the American Registry of Pathology and The World Health Organization Collaborating Center for Comparative Oncoloy. 2002.

5. Valli, V. E. and R. M. Jacobs. Structure and function of the hemopoietic

system. In: Schalm’s Veterinary Hematology, 5th edition, Lea & Febiger. 2002.

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6. Jacobs, R. M., V. E. Valli, and J. B. Messick. Tumors of the hemolymphatic system. In: Moulton’s Tumors in Domestic Animals, 4th edition. University of California Press. 2002.

7. Jacobs , R. M., J. H. Lumsden, J. A. Taylor. Canine and feline reference

values. Current Veterinary Therapy XIII, W. B. Saunders Co., Philadelphia, pp. 1207-1227, 2000.

8. Jacobs, R.M., B. Jefferson, and D. Suarez. Prevalence, determined by

serology and proviral detection, of bovine immunodeficiency-like virus (BIV) in bulls. Dairy Research Report sponsored by OMAFRA and Agriculture and Agri-Food Canada, University of Guelph, May 1997.

9. Jacobs, R. M. Applying cytology in your practice: when to use it, getting

the sample, the cytological approach to getting an answer. Proceedings of the World Small Animal Veterinary Association, Jerusalem, October, 1996

10. Jacobs, R. M. Lesions the practitioner can confidentally identify using

cytology and Ahow to communicate with your pathologist@. Proceedings of the World Small Animal Veterinary Association, Jerusalem, October, 1996

11. Grodecki, K.M. M.J. Gains and R.M. Jacobs. The effect of an angiotensin

converting enzyme inhibitor on the progression of Samoyed Hereditary Glomerulonephritis. Pet Trust Clinical Factsheet, University of Guelph, May, 1995.

12. Jacobs, R.M., Lumsden, J.H. and W. Vernau. Canine and feline reference

values. Current Veterinary Therapy XII, 1995.

13. Jacobs R., H.E. Smith, C.A Whetstone, D.L. Suarez and B. Jefferson. Hematological and lymphocyte subset analyses in sheep inoculated with bovine immunodeficiency-like virus. Dairy Research Report sponsored by OMAFRA and Agriculture and Agri-Food Canada, University of Guelph, May 1995.

14. Jacobs, R.M., W.B. McNab, F.L. Pollari and B. Jefferson. A serological

survey of bovine syncytial virus in Ontario: Associations with bovine leukemia and immunodeficiency-like viruses, production records, and management practices. Dairy Research Report, University of Guelph, May 1994.

15. Jacobs, R.M., Z. Song, H. Poon, J.L. Heeney, J.A. Taylor, B. Jefferson, W.

Vernau and V.E.O. Valli. Proviral detection and serology in bovine leukemia virus-exposed normal cattle and cattle with lymphoma. Dairy Research Report, Univeristy of Guelph, May, 1993.

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16. Jacobs, R.M., H.E. Smith, B. Gregory, V.E.O. Valli and C.A. Whetstone. Detection of multiple retroviral infections in cattle and cross-reactivity of bovine immunodeficiency-like virus and human immunodeficiency virus type 1 proteins using bovine and human sera in a Western blot assay. Dairy Research Report, Univeristy of Guelph, May, 1993.

17. Jacobs, R.M., J.L. Heeney, M.A. Godkin, K.E. Leslie, J.A. Taylor, C. Davies and V.E.O. Valli. Production and related variables in bovine leukemia virus-infected cows. Dairy Research Report, Univeristy of Guelph, May, 1993.

18. McNab, W.B., R.M. Jacobs and H.E. Smith. A serological survey for

bovine immunodeficiency-like virus in Ontario dairy cattle and associations between test results, production records, and management practices. Dairy Research Report, Univeristy of Guelph, May, 1993.

19. Jacobs, R.M. Evaluation of hepatocyte integrity and hepatic function.

Clinical Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

20. Jacobs, R.M. Water, electrolyte, and acid-base disorders. Clinical

Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

21. Jacobs, R.M. Renal system: glomerular and tubular function. Clinical

Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

22. Jacobs, R.M. Anemia - Diagnostic approach and classification. Clinical

Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

23. Jacobs, R.M. Leukocyte changes in non-neoplastic diseases. Clinical

Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

24. Jacobs, R.M. Cytology for the practitioner. Clinical Pathology: A

Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

25. Jacobs, R.M., Lumsden, J.H. and W. Vernau. Canine and feline reference

values. Current Veterinary Therapy XI, 1992.

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26. Jacobs, R.M., J.H. Lumsden and E. Grift. Evaluation of interferences in non-human specimens. "Towards Perfection in Clinical Chemistry Analyses. Reducing the Impact of Non-specific Results Due to Interferences" by M.R. Glick, K.W. Rider, December 1991.

27. Jacobs, R.M. Hyperglycemia and hypoglycemia. Small Animals Medicine,

ed. D.G. Allan, J.B. Lippincott Co., Philadelphia, 1990.

28. Jacobs, R.M. Interpretation of serum titers. Small Animal Medicine, ed. D.G. Allan, J.B. Lippincott Co., Philadelphia, 1990.

29. Jacobs, R.M. Anemia. Small Animal Medicine, ed. D.G. Allan, J.B.

Lippincott Co., Philadelphia, 1990.

30. Jacobs, R.M. Polycythemia. Small Animal Medicine, ed. D.G. Allan, J.B. Lippincott Co., Philadelphia, 1990.

31. Veterinary Teaching Hospital Manual - Clinical Pathology Section.

Updated annually.

32. Jacobs, R.M. (Guest Editor). Cytology of the Dog and Cat. Seminars in Veterinary Medicine and Surgery (Small Animal). Grune and Stratton, 1988.

33. Couto, C.G. and R.M. Jacobs. Disorders of Leukocytes and Leukopoiesis.

In The Cat: Diseases and Clinical Management. ed. R. Sherding. Churchill Livingstone, New York, 1989, pp. 557-572.

34. Jacobs, R.M. 1986. Bovine lymphoma. In Comparative Pathobiology of

Viral Diseases, eds. R. Olsen, S. Krakowka, J. Blakeslee. CRC Reviews, Baton Rouge, pp 21-51.

35. Jacobs, R.M. and R.L. Hall. Bovine lymphoma: A self-instructional

program. Division of Educational Resources, College of Veterinary Medicine, The Ohio State University, 1935 Coffey Road, Columbus, OH 43210.

Letters, Notes and Short Communications in Refereed Journals

1. Jacobs, R.M., J. Gross-Sobol, E. Grift, and J.H. Lumsden. Cost cutting: A false economy. Canadian Veterinary Journal, April, 1997.

2. Jacobs, R.M. Commercial kit for prothrombin time. Advances in Small

Animal Medicine and Surgery, 9:4-6, 1996

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3. Rand, J.S., J. Parent and R.M. Jacobs. Reference intervals for feline CSF. Journal of Veterinary Internal Medicine, 3: 118, 1989.

4. Rand, J.S., J. Parent and R.M. Jacobs. CSF analysis in 61 cats with CNS

disease. Journal of Veterinary Internal Medicine, 3: 118, 1989.

5. Jacobs, R.M. Quantitative buffy coat analysis. Advances in Small Animal Medicine and Surgery, 1: 1-2, 1988.

6. Jacobs, R.M. The Coombs' test in canine immune hemolytic anemia

(letter). Compendium Small Animal Medicine, July 1988.

7. Jacobs, R.M. Ophthalmologic Cytology. Seminars in Veterinary Medicine and Surgery (Small Animal). May 1988.

8. Jacobs, R.M. Amylase in canine salivary gland (letter). Research

Communications Chemical Pathology and Pharmacology. March 1987.

9. Jacobs, R.M. Experimental canine pancreatitis (letter). Journal American Animal Hospital Association 22: 147, 1986.

10. Jacobs, R.M. and M.L. Wellman. Canine serum alkaline phosphatases

(note). Journal Veterinary Clinical Pathology 24: 4, 1986.

11. Jacobs, R.M. and R.J. Murtaugh. Comments on isoamylases (letter). American Journal Veterinary Research 46: 1598-1599, 1985.

12. Hayes, T. and R.M. Jacobs. Myoglobinuria in the horse (letter).

Compendium Continuing Education 7: 212-213, 1985 Papers in refereed journals

1. Quiroz-Rocha GF, S LeBlanc, T Duffield, B Jefferson, D Wood, KE Leslie and RM Jacobs. Short Communication: Effect of sampling time relative to the first daily feeding on interpretation of serum fatty acid and beta-hydroxybutyrate concentrations in dairy cattle. Journal of Dairy Science 93: 2030-2033, 2010.

2. Quiroz-Rocha GF, S LeBlanc, T Duffield, B Jefferson, D Wood, KE Leslie

and RM Jacobs. Reference limits for biochemical and hematological analytes of dairy cows one week before and one week after parturition. Canadian Veterinary Journal 50: 383-8, 2009.

3. Quiroz-Rocha GF, S LeBlanc, T Duffield, D Wood, KE Leslie and RM Jacobs. Evaluation of prepartum serum cholesterol and fatty acid

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concentrations as predictors of postpartum retention of the placenta in dairy cows. Journal American Veterinary Medical Association 234: 790-3, 2009.

4. Bartleman AP, Jacobs R, Kirkland JB. Niacin supplementation decreases the incidence of alkylation-induced nonlymphocytic leukemia in Long-Evans rats. Nutrition and Cancer 60: 251-8, 2008

5. VanDenHeuvel M, Copeland KF, Cates EC, Jefferson B, Jacobs RM.

Defibrinated bovine plasma inhibits retroviral transcription by blocking p52 activation of the NfkappaB element in the long terminal repeat. Canadian Journal of Veterinary Research, 71: 119-28, 2007.

6. Whiteside DP, Barker IK, Conlon PD, Tesoro A, Thiessen JJ, Mehren KG,

Jacobs RM, Spino M. Pharmacokinetic disposition of the oral iron chelator deferiprone in the domestic pigeon (Columbia livia). Journal Avian Medicine Surgery. 21: 121-9, 2007.

7. Whiteside DP, Barker IK, Conlon PD, Tesoro A, Thiessen JJ, Mehren KG,

Jacobs RM, Spino M. Pharmacokinetic disposition of the oral iron chelator deferiprone in the white leghorn chicken. Journal Avian Medicine Surgery. 21: 110-20, 2007.

8. Perry J, Ho M, Viero S, Zheng K, Jacobs R, Thorner PS. The intermediate filament nestin is highly expressed in normal human podocytes and podocytes in glomerular disease. Pediatric and Developmental Pathology. 10: 369-82, 2007

9. Harvey SJ, Perry J, Zheng K, Chen D, Sado Y, Jefferson B, Jacobs R,

Thorner PS. Type IV collagen induces podocytic features in bone marrow stromal stem cells in vitro. Journal American Society Nephrology 17: 66-76, 2006.

10. Harvey SJ, Perry J, Zheng K, Chen D, Sado Y, Jefferson B, Ninomiya Y,

Jacobs RM, Hudson BG, Thorner PS. Sequential expression of type IV collagen networks: Testis as a model and relevance to spermatogenesis. American Journal Pathology 168: 1587-1597, 2006

11. Perry J, Tam S, Zheng K, Sado Y, Dobson H, Jefferson B, Jacobs R,

Thorner PS. Type IV collagen induces podocytic features in bone marrow stromal stem cells in vitro. Journal American Society of Nephrology 17(1):66-76, 2006

12. Keller SL, Jefferson BJ, Jacobs RM, Wood DR. Effects of noncytopathic

type 2 Bovine viral diarrhea virus on proliferation of bone marrow progenitor cells. Canadian Journal of Veterinary Research 70:20-27, 2006

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13. Zheng K, Perry J, Harvey SJ, Sado Y, Ninomiya Y, Jefferson B, Jacobs R,

Hudson BG, Thorner PS. Regulation of collagen type IV genes is organ-specific: evidence from a canine model of Alport syndrome. Kidney International. 68(5):2121-30, 2005

14. van den Heuvel MJ, Jefferson BJ, Jacobs RM. Purified bovine plasma blocking factor decreases Bovine leukemia virus p24 expression while increasing protein synthesis and transcriptional activity of peripheral blood mononuclear cells in short-term culture. Canadian Journal Veterinary Research 69(3):186-92, 2005

15. van den Heuvel MJ, Jefferson BJ, Jacobs RM. Isolation of a bovine

plasma fibronectin-containing complex which inhibits the expression of bovine leukemia virus p24. Journal of Virology 79(13):8164-70, 2005

16. Jacobs RM. Serum angiotensin-converting enzyme activity is not a useful

biomarker for canine splenic haemangiosarcoma. Journal of Comparative Clinical Pathology, 13:86-7, 2004.

17. Keller SL, Wood RD, Jefferson BJ, Jacobs RM. Use of a commercial

methylcellulose medium with and without recombinant bovine granulocyte colony-stimulating factor for culturing bovine bone marrow cells. Canadian Journal of Veterinary Research 68:157-9, 2004.

18. Tant, MS, Lumsden JH, Jacobs RM, Bonnett BN. Evaluation of

acanthocyte count as a diagnostic test for canine hemangiosarcoma. Journal Comparative Clinical Pathology 12: 174-181, 2004.

19. Deregt D, Jacobs RM, Carman PS, Tessaro SV. Attenuation of a virulent

type 2 bovine viral diarrhea virus. Veterinary Microbiology 100:151-61, 2004.

20. Whiteside DP, Barker IK, Mehren KG, Jacobs RM, Conlon PD. Clinical

evaluation of the oral iron chelator deferiprone for the potential treatment of iron overload in bird species. J Zoo Wildl Med. 2004 Mar;35(1):40-9.

21. Wood RD, Goens SD, Carman PS, Deregt D, Jefferson B, Jacobs RM.

Effect on hematopoietic tissue of experimental infection of cavles with non-cytopathic type 2 bovine virual diarrhea virus. Canadian Journal of Veterinary Research 68:42-48, 2004.

22. VanDenHeuvel M, Portetelle D, Jefferson B, Jacobs RM. Adaptation of a

sandwich enzyme-linked immunosorbent assay to determine the

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concentration of bovine leukemia virus p24 and optimal conditions for p24 expression in short-term cultures of peripheral blood mononuclear cells. Journal of Virological Methods 111:61-7, 2003.

23. Harvey SJ, Zheng K, Jefferson B, Moak P, Sado Y, Naito I, Ninomiya Y,

a canine model of Alport syndrome. American Journal of Pathology 162:873-885, 2003.

24. Chen, D., Jefferson, B., Harvey, S., Zheng, K., Bartley, C., Jacobs, R., and

P. Thorner. Cyclosporine A slows the progressive renal disease of Alport syndrome (X-linked hereditary nephritis): Results from a canine model. Journal American Society of Nephrology, 14: 690-8, 2003.

25. Boyonoski, A.C., J.C. Spronck, R.M. Jacobs, G.M. Shah, G.G. Poirier, and

J.B. Kirkland. Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. Journal of Nutrition 132: 115-120, 2002.

26. Boyonoski, A.C., J.C. Spronck, L.M. Gallacher, R.M. Jacobs, G.M. Shah,

G.G. Poirier, and J.B. Kirkland. Niacin deficiency decreases bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. Journal of Nutrition 132: 108-114, 2002.

27. Harvey SJ, Mount R, Sado Y, Naito I, Ninomiya Y, Harrison R, Jefferson

B, Jacobs R, Thorner PS. The inner ear of dogs with X-linked nephritis provides clues to the pathogenesis of hearing loss in X-linked Alport syndrome. Am J Pathol. 159:1097-1104, 2001.

28. Gonzalez, G.C, J.B. Johnston, D.D. Nickel, R. M. Jacobs, M. Olson, and

C. Power. Absence of bovine immunodeficiency virus in Western Canada. Can. J. Vet. Res. 65:73-6, 2001.

29. Valli, V. E. O., R. Jacobs, A. Norris, G. Couto, W. Morrison, D. McCaw, S.

Cotter, G. Ogilvie, A. Moore. The histologic classification of 602 cases of feline lymphoprolferative disease using the National Cancer Institute working formulation. J. Vet. Diagnostic Investigation 12, 295-306, 2000

30. Boyonoski, A., Gallacher, L. M., ApSimon, M. M., Jacobs, R. M., Shah, G.

M., Poirier, G.G., and J. B. Kirkland. Niacin deficiency in rats increases the severity of ethylnitrosourea-induced anemia and leukopenia. J. Nutrition 130, 1102-1107, 2000.

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31. Boyonoski, A., L. Gallacher, M. ApSimon, R. Jacobs, G.M. Shah, G.G.

Poirier, and J.B. Kirkland. Niacin deficiency increases the sensitivity of rats to the short and long term effects of ethylnitrosourea treatment. Molecular and Cellular Biochemistry 193, 83-87, 1999.

32. Jorundsson, E., J. Lumsden, R. Jacobs. Rapid staining techniques in

cytopathology: A review and comparison of modified protocols for H & E, Papanicolaou and Romanowsky stains. Vet. Clin. Path. 28, 100-108, 1999.

33. Abed, Y., G. St-Laurent, H. Zhang, R. Jacobs, D. Archambault.

Development of a Western blot assay for detection of bovine immunodeficiency like virus using capsid and transmembrane envelope protein expressed from recombinant baculovirus. Clinical and Diagnostic Laboratory Immunology 6, 168-172, 1999.

34. Trochta, O., R.M. Jacobs, B.Jefferson. Isolation and short-term culture of

canine adrenal microvascular endothelial cells. Canadian Journal of Veterinary Research 63, 1-4, 1999.

35. Zheng, K., S. Harvey, Y. Sado, I. Naito, Y. Ninomiya, R. Jacobs, and P.

Thorner. Absence of alpha 5(IV) in Alports syndrome is related to failure at the protein assembly level and does not result in diffuse leiomyomatosis. American Journal of Pathology 154, 1883-1892, 1999

36. Saini, S.S., Allore, B., Jacobs, R.M., and A. Kaushik. Exceptionally long CDR3H region with multiple cysteine residues in functional bovine IgM antibodies. European Journal of Immunology 29, 2420-6, 1999.

37. Harvey, S.J., K. Zheng, Y. Sado, I. Naito, Y. Ninomiya, R.M. Jacobs, B.G.

Hudson, and P.S. Thorner. The role of distinct type IV collagen networks in glomerular development and function. Kidney International 54, 1857-1866, 1998.

38. Vernau, W., R.M. Jacobs, C. Davies, R.F. Carter and V.E.O. Valli. A

morphometric analysis of bovine lymphomas. Journal of Comparative Pathology, 118:281-289, 1998.

39. Jacobs. R.M., B.J. Jefferson, and D.L. Suarez. Prevalence, determined by

serology and proviral detection, of bovine immunodeficiency-like virus in bulls. Canadian Journal of Veterinary Research 62: 231-233, 1998.

40. Vernau, W., R.M. Jacobs, V.E.O. Valli and J.L. Heeney. The

immunophenotypic characterization of bovine lymphomas. Veterinary Pathology 34:222-225, 1997.

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41. Grodecki, K., M.J. Gains, R. Baumal, D.H. Osmond, B. Cotter, V.E.O. Valli and R.M. Jacobs. ACE inhibitor treament of X-linked hereditary nephritis in Samoyed dogs. Journal of Comparative Pathology, 117:209-225, 1997.

42. Straw, R., B. Powers, J. Klauser, R. A. Henderson, W. Morrison, D. L.

McCaw, H. J. Harvey, R. M. Jacobs, and J. R. Berg. Canine mandibular osteosarcoma: 51 cases (1980-1992). J American Animal Hospital Association 32, 257-263, 1996.

43. Thorner, P.S., K. Zheng, R. Kalluri, R. Jacobs and B.G. Hudson.

Coordinate gene expression of the α3, α4, and α5 chains of collagen type IV. Journal of Biological Chemistry 271:13821-13828, 1996.

44. Jacobs, R. M., W. B. McNab, F. L. Pollari and B. Jefferson. A serological

survey for bovine immunodeficiency-like, bovine leukemia, and bovine syncytial viruses in Ontario dairy cattle and associations between test results, production records, and management practices. Canadian Journal of Veterinary Research 59:271-278, 1995.

45. Jacobs, R. M., H. E. Smith, L. J. McCutcheon and V. E. O. Valli.

Histopathological Changes in the Lymphoid Tissues of Sheep Exposed to the Bovine Immunodeficiency-Like Virus. Journal of Comparative Pathology 114:23-30, 1995.

46. Valli VE, Norris A, Jacobs RM, Laing E, Withrow S, Macy D, Tomlinson J, McCaw D, Ogilvie GK, Pidgeon G, Henderson RA. Pathology of canine bladder and urethral cancer and correlation with tumor progression and survival. Journal of Comparative Pathology 113:113-130, 1995

47. Gains, M.J., K. M. Grodecki, R. M. Jacobs, D. Dyson, R. A. Foster.

Comparison of direct and indirect blood pressure measurements in anaesthetized dogs. Canadian Journal of Veterinary Research 59:238-240, 1995

48. Jacobs RM, Smith HE, Whetstone CA, Suarez DL, Jefferson B, Valli VEO.

Hematological and lymphocyte subset analyses in sheep inoculated with bovine immunodeficiency-like virus. Veterinary Research Communications 18:471-482, 1994

49. Smith HE, Jacobs RM, Mallard B. Cell-mediated and humoral immunity in

sheep exposed to bovine immunodeficiency-like virus. Comparative Immunology, Microbiology and Infectious Disease 17:29-39, 1994

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50. Bienzle D., R.M. Jacobs, J.H. Lumsden, E. Grift, L. Tarasov. Comparison of two automated multichannel haematology analyzers in domestic animals. Comparative Hematology International 4:162-166, 1994

51. Schnurr, M.W., R.F. Carter, I.D. Dube, V.E. Valli and R.M. Jacobs.

Nonrandom chromosomal abnormalities in bovine lymphoma. Leukemia Research 18:91-99, 1994

52. Smith, H.E., R.M. Jacobs and C. Smith. Flow cytometric analysis of ovine

peripheral blood lymphocytes. Canadian Journal of Veterinary Research 58:152-155, 1994

53. Bienzle, D., Abrams-Ogg, A.C.G., Kruth, S.A., Ackland-Snow, J., Carter,

R.F., Dick, J.E., Jacobs, R.M., Kamel-Reid, S. and I.D. Dubé. Gene transfer into hematopoietic stem cells: Long-term maintenance of in vitro activated progenitors without marrow ablation. Proceedings National Academy of Science 91:350-354, 1994

54. McNab W. B., R. M. Jacobs and H. E. Smith. A serological survey for

bovine immunodeficiency-like virus in Ontario dairy cattle and associations between test results, production records, and management practices. Canadian Journal of Veterinary Research 58:36-41, 1994

55. Rand, J. S., J. Parent, D. Percy and R. M. Jacobs. Clinical, cerebrospinal

fluid, and histological data from 34 cats with primary non-inflammatory central nervous system disease. Canadian Veterinary Journal 35: 103-110, 1994.

56. Rand, J. S., J. Parent, D. Percy and R. M. Jacobs. Clinical, cerebrospinal

fluid, and histological data from 27 cats with primary inflammatory central nervous system disease. Canadian Veterinary Journal 35:174-181, 1994.

57. Bienzle D., R.M. Jacobs, J.H. Lumsden. Relationship of serum total

calcium to serum albumin in dogs, cats, horses, and cattle. Canadian Veterinary Journal 34:360-364, 1993

58. Nadin-Davis, S. A., S. C. Chang, H. E. Smith and R. M. Jacobs. Detection

of bovine immunodeficiency-like virus by polymerase chain reaction. Journal of Virological Methods 42:323-336, 1993.

59. Taylor, J. A. and R. M. Jacobs. Effects of plasma and serum on the in

vitro expression of bovine leukemia virus. Laboratory Investigation 69:340-346, 1993.

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60. Smith, H. E. and R. M. Jacobs. Serological evidence of bovine immunodeficiency-like virus infection in a sheep. Canadian Journal of Veterinary Research 57:305-306, 1993.

61. Poon, H., E. Jimenez, Z. Song, B. Jefferson and R.M. Jacobs. Bovine

leukemia viral RNA detection in serum using the polymerase chain reaction. Journal of Virological Methods 41:101-112, 1993.

62. Thorner, P. S., R. Baumal, V. E. O. Valli, D. Mahuran, P. M. Marrano and

R. M. Jacobs. Production of anti-NC1 antibody by affected male dogs with X-linked hereditary nephritis: a probe for assessing the NC1 domain of collagen type IV in dogs and humans with hereditary nephritis. Virchows Arch (A) 421:467-475, 1992.

63. Jacobs, R.M., H.E. Smith, B. Gregory, V.E.O. Valli and C.A. Whetstone.

Detection of multiple retroviral infections in cattle and crossreactivity of BIV and HIV-1 proteins using bovine and human sera in a Western blot assay. Canadian Journal of Veterinary Research 56:353-359, 1992.

64. Jacobs, R.M., Z. Song, H. Poon, J.L. Heeney, J.A. Taylor, B. Jefferson, W.

Vernau and V.E.O. Valli. Proviral detection and serology in bovine leukemia virus-exposed normal cattle and cattle with lymphoma. Canadian Journal of Veterinary Research 56: 339-348, 1992.

65. Jacobs, R.M., J.H. Lumsden, and E. Grift. Effects of bilirubinemia,

hemolysis, and lipemia on clinical chemistry anlaytes in bovine, canine, equine, and feline sera. Canadian Veterinary Journal 33:605-608, 1992.

66. Heald, M.T.S., D. Waltner-Toews, R.M. Jacobs and W.B. McNab. The

prevalence of anti-bovine leukemia virus antibodies in dairy cows and associations with farm management practices, production and culling in Ontario. Veterinary Preventive Medicine 14:45-55, 1992.

67. Bloomberg R. M., H. A. Pook, R.M. Jacobs and J. M. VanGorder. Human

recombinant erythropoietin therapy in a cat with chronic renal failure. Canadian Veterinary Journal 33:612-613, 1992.

68. Heeney, J.L., P.J.S. Valli, R.M. Jacobs and V.E.O. Valli. Evidence for

bovine leukemia virus infection of peripheral blood monocytes and limited antigen expression in bovine lymphoid tissue. Laboratory Investigation 66:608-617, 1992.

69. Norris, A.M., E.J. Laing, V.E.O. Valli, S.J. Withrow, D.W. Macy, G.K.

Ogilvie, J. Tomlinson, D. McCaw, G. Pidgeon and R.M. Jacobs. Canine bladder and urethral tumors: A retrospective study of 115 cases (1980-1985). Journal of Veterinary Internal Medicine 6:145-153, 1992.

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70. Vernau, W., V.E.O. Valli, T.W. Dukes, R.M. Jacobs, M. Shoukri and J.L.

Heeney. Classification of 1,198 cases of bovine lymphoma using the National Cancer Institute Working Formulation for human non-Hodgkin's lymphomas. Veterinary Pathology 29:183-195, 1992.

71. Baumal, R., P. Thorner, V.E.O. Valli, R. McInnes, P. Marrano, R. Jacobs,

A. Binnington and A. Bloedow. Renal disease in carrier female dogs with x-linked hereditary nephritis implications for female patients with this disease. American Journal of Pathology 139:751-764, 1991.

72. Jacobs, R.M., J.L. Heeney, M.A. Godkin, K.E. Leslie, J.A. Taylor, C.

Davies and V.E.O. Valli. Production and related variables in bovine leukaemia virus-infected cows. Veterinary Research Communications 15:463-474, 1991.

73. O'Brien, P.J., B.I. Kalow, B.D. Brown, J.H. Lumsden and R.M. Jacobs.

Porcine malignant hyperthermia susceptibility: Halothane-induced increase in cytoplasmic free calcium in lymphocytes. American Journal of Veterinary Research 50:131-135, 1989.

74. Valli, V.E.O., R. Baumal, P. Thorner, R. Jacobs, P. Marrano, C. Davies, B.

Qizilbash and H. Clarke. Dietary modification reduces splitting of glomerular basement membranes and delays death due to renal failure in canine x-linked hereditary nephritis. Laboratory Investigation 65:67-73, 1991.

75. Jacobs, R.M., J.H. Lumsden, J.A. Taylor and E. Grift. Effects of

interferents on the kinetic Jaffé reaction and an enzymatic colorimetric test for serum creatinine concentration determination in cats, cows, dogs and horses. Canadian Journal of Veterinary Research 55:150-154, 1991.

76. Jacobs, R.M., J.H. Lumsden, J.A. Taylor and E. Grift. Analyte

comparisons on the Coulter Dacos and Kodak Ektachem DT-60 clinical chemistry analyzers. Canadian Veterinary Journal 32:30-34, 1991.

77. Lumsden, J.H., R.M. Jacobs and P. Physick-Sheard. Contribution of delta

bilirubin to the interpretation of hyperbilirubinemia in the horse - a pilot study. Canadian Veterinary Journal 32:169-172, 1991.

78. Rand, J.S., J. Parent, R.M. Jacobs and D. Percy. Reference intervals for

feline cerebrospinal fluid: cell counts and cytologic features. American Journal of Veterinary Research 51:1044-1048, 1990.

79. Rand, J. S., J. Parent, R.M. Jacobs and R. Johnson. Reference intervals

for feline cerebrospinal fluid: biochemical and serologic variables, IgG

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concentration, and electrophoretic fractionation. American Journal of Veterinary Research 51:1049-1054, 1990.

80. Kohn, C.W., R.M. Jacobs, D. Knight, W. Hueston, A.A. Gabel and S.M.

Reed. Microcytosis, hypofferremia, hypoferritemia, and hypertransferrinemia in Standardbred foals from birth to 4 months of age. American Journal of Veterinary Research 51:1198-1205, 1990.

81. Jacobs, R.M., S. M. Cochrane, J.H. Lumsden and A.M. Norris.

Relationship of cerebrospinal fluid protein concentration determined by dye-binding and urinary dipstick methodologies. Canadian Veterinary Journal 31:587-588, 1990.

82. Ellison, R.S. and R.M. Jacobs. An attempt to determine the tissue origins

of equine serum alkaline phosphatase by isoelectric focusing. Canadian Journal of Veterinary Research 54:119-125, 1990.

83. Ellison, R.S. and R.M. Jacobs. The isoelectric focusing properties of

serum alkaline phosphatase in disease and following prednisolone and phenylbutazone administration in the horse. Canadian Journal of Veterinary Research 54:126-131, 1990.

84. Jacobs, R.M., G.J.D. Smith, V.E.O. Valli, C. Dupont and W.A. McCormick.

A program for storage and retrieval of demographic, sample, clinical laboratory, and restriction endonuclease map data. Computer Methods and Programs in Biomedicine 29:251-256, 1989.

85. Lumsden, J.H. and R.M. Jacobs. Clinical Chemistry: In-clinic analysis,

quality control, reference values, and system selection. Veterinary Clinics of North America: Small Animal Practice 19:875-897, 1989.

86. Jacobs, R.M., A.M. Norris, J.H. Lumsden and V.E.O. Valli. Laboratory

diagnosis of malassimilation. Veterinary Clinics of North America: Small Animal Practice 19:951-977, 1989.

87. Taylor, J.A., R.M. Jacobs, J.H. Lumsden and B.N. Bonnett. Perspectives

on the diagnosis of feline hyperthyroidism. Canadian Veterinary Journal 30:477-481, 1989.

88. Rae, C.A., R.M. Jacobs and C.G. Couto. A comparison between the

cytological and histological characteristics in thirteen canine and feline thymomas. Canadian Veterinary Journal 30:497-500, 1989.

89. Jacobs, R.M. Relationship of urinary amylase activity and proteinuria in

the dog. Veterinary Pathology 26:349-350, 1989.

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90. Jacobs, R.M. The origins of canine serum amylases and lipase. Veterinary Pathology 26:525-527, 1989.

91. Jacobs, R.M. Renal disposition of amylase, lipase, and lysozyme in the

dog. Veterinary Pathology 25:443-449, 1988.

92. Wellman, M.L., S. Krakowka, R.M. Jacobs and G.J. Kociba. A macrophage-monocyte cell line from a dog with malignant histiocytosis. In Vitro Cellular and Developmental Biology 24:223-229, 1988.

93. Jacobs, R.M., C.L. Swenson, D.J. Davenport and R.J. Murtaugh.

Sensitivity and specificity of canine serum total amylase and isoamylase activity determinations. Canadian Journal of Veterinary Research 52:473-475, 1988.

94. Jacobs, R.M. and V.E.O. Valli. Bone marrow biopsies: Principles and

perspectives of interpretation. Seminars in Veterinary Medicine and Surgery (Small Animal) 3:176-192, 1988.

95. Fingeroth, J.M., D.D. Smeak and R.M. Jacobs. Intravenous methylene

blue infusion for intraoperative identification of parathyroid gland and pancreatic islet cell tumors in dogs. Part 1: Experimental determination of dose-related staining efficacy and toxicity. Journal of the American Animal Hospital Association 24:165-173, 1988.

96. Swenson, C.L., G.J. Kociba, D.A. O'Keefe, M.S. Crisp, R.M. Jacobs and

J.L. Rojko. Cyclic hematopoiesis associated with feline leukemia virus infection in two cats. Journal of the American Veterinary Medical Association 191:93-96, 1987.

97. Jacobs, R.M., J.H. Lumsden and E. Willet. Potential inadequacy of the

TSH stimulation test in the diagnosis of canine hypothyroidism. Canadian Veterinary Journal 28:432-433, 1987.

98. O'Keefe, D.A., C.G. Couto, C. Burke-Schwartz and R.M. Jacobs. Systemic

mastocytosis in 16 dogs. Journal of Veterinary Internal Medicine 1:75-80, 1987.

99. Seide, R.K., R.M. Jacobs, T.N. Dobblestein and J.M. Kehoe.

Characterization of a homogeneous paraprotein from a horse with spontaneous multiple myeloma syndrome. Veterinary Immunology and Immunopathlogy 17:69-78, 1987

100. Jacobs, R.M., J.T. Boyce and G.J. Kociba. Flow cytometric and

radioisotopic determinations of platelet survival time in normal cats and feline leukemia virus-infected cats. Cytometry 7:64-69, 1986.

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101. Jacobs, R.M., R.J. Murtaugh and R.H. Fertel. Platelet function in

experimentally induced pancreatitis in the dog. Thrombosis and Haemostasis 55:197-200, 1986.

102. Stirtzinger, T., V.E.O. Valli, R.M. Jacobs, L. Beiner and B. Jansen. In

vitro response of purified ovine peripheral blood lymphocytes to phytohemagglutinin-M. Canadian Journal of Veterinary Research 50:115-117, 1986.

103. Boyce, J.T., G.J. Kociba, R.M. Jacobs and M.G. Weiser. Feline

leukemia virus-induced thrombocytopenia and macrothrombocytosis in cats. Veterinary Pathology 23:16-20, 1986.

104. Jacobs, R.M., C.G. Couto and M.L. Wellman. Biclonal gammopathy

in a dog with myeloma and cutaneous lymphoma. Veterinary Pathology 23:211-213, 1986.

105. Jacobs, R.M., R.J. Murtaugh, R.G. Sherding and T.M. O'Dorisio.

Effects of xylazine administration on serum amylase, pancreas-specific isoamylase and pancreatic polypeptide in normal dogs. Canadian Journal of Veterinary Research 50:123-125, 1986.

106. Fossum, T.W., S.J. Birchard and R.M. Jacobs. Chylothorax in 34

dogs. Journal of the American Veterinary Medical Association 188:1315-1318, 1986.

107. Swenson, C. and R.M. Jacobs. Spherocytosis associated with

anaplasmosis in two cows. Journal of the American Veterinary Medical Association 188:1061-1063, 1986.

108. Fossum, T.W., R.M. Jacobs and S.J. Birchard. Evaluation of

cholesterol and triglyceride concentrations in differentiating chylous and nonchylous pleural effusions in dogs and cats. Journal of the American Veterinary Medical Association 188:49-51, 1986.

109. Jacobs, R.M., R.J. Murtaugh and W.D. Dehoff. Review of the

clinicopathological findings of acute pancreatitis in the dog: Use of an experimental model. Journal of the American Animal Hospital Association 21:795-800, 1985.

110. Wellman, M.L., D.J. Davenport, D. Morton and R.M. Jacobs. Malignant

histiocytosis in four dogs. Journal of the American Veterinary Medical Association 187:919-921, 1985.

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111. Murtaugh, R. and R.M. Jacobs. Immune Mediated Megakaryocytic Aplasia in a Dog. Journal American Veterinary Medical Association 186:1313-1315, 1985.

112. Murtaugh, R.J. and R.M. Jacobs. Serum Amylase and Isoamylases

and Their Origins in Healthy Dogs and Dogs with Experimentally Induced Acute Pancreatitis. American Journal of Veterinary Research 46:742-747, 1985.

113. Dean, P.W., J.T. Robertson and R.M. Jacobs. Comparison of suture

materials and suture patterns for inverting intestinal anastomosis of the jejunum in the horse. American Journal of Veterinary Research 46: 2072-2077, 1985.

114. Murtaugh, R.J., R.M. Jacobs, R.G. Sherding, and T.M. O'Dorisio.

Serum Pancreatic Polypeptide and Amylase Concentrations in Dogs with Experimentally Induced Acute Pancreatitis. American Journal of Veterinary Research 46:654-656, 1985.

115. Murtaugh, R.J. and R.M. Jacobs. Serum Antiprotease Concentrations

in Dogs with Experimentally Induced Pancreatitis. American Journal of Veterinary Research 46:80-83, 1985.

116. Murtaugh, R.J., D.S. Herring, and R.M. Jacobs. Ultrasonographic Changes in Dogs with Experimentally Induced Pancreatitis. Veterinary Radiology 26:27-32, 1985.

117. Murtaugh, R. and R.M. Jacobs. Trichomoniasis of the Crop in a

Cockatiel. Journal American Veterinary Medical Association 185:441-442, 1984.

118. Welker, F.H., G.F. Hoffsis, D.M. Rings, B.L. Hull and R.M. Jacobs.

Broncobiliary Fistula in a Cow. Journal American Veterinary Medical Association 185:440-441, 1984.

119. Jacobs, R.M., R. Murtaugh and D. Crocker. A Retrospective Analysis of Immuno-Hemolysis in the Dog Detected by a Microtitration Agglutination Test. Journal American Veterinary Medical Association 185:66-69, 1984.

120. Murtaugh, R.J. and R.M. Jacobs. Antinucleolar Antibody Associated

with Lupus Erythematosus in a Dog. Journal Veterinary Clinical Pathology 12:29-31, 1983.

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121. Jacobs, R.M., G.J. Kociba and W.W. Ruoff. Monoclonal Gammopathy in a Horse with Defective Hemostasis. Veterinary Pathology 20:643-647, 1983.

122. Reinemeyer, C.R., R.M. Jacobs and G.N. Spurlock. A Coccidial

Sporocyst in Equine Urine. Journal American Veterinary Medical Association 182:1250-1251, 1983.

123. Jacobs, R.M. The Qualitative Analysis of Canine Immunoglobulins and

Myeloma Proteins by Immunofixation. Journal Veterinary Clinical Pathology 11:7-10, 1982.

124. Jacobs, R.M., R.L. Hall and W.A. Rogers. Isoamylases in Clinically

Normal and Diseased Dogs. Journal Veterinary Clinical Pathology 11:26-32, 1982.

125. Jacobs, R.M., B. Horney and L. Beiner. Cutaneous Response to PHA-

M and Hematologic Changes in Corticosteroid-Treated Cows. Canadian Journal of Comparative Medicine 45:384-387, 1981.

126. Jacobs, R.M., V.E.O. Valli, B.N. Wilkie and A.C. Hollinshead. Partial

Purification of a Common antigen in Bovine Lymphoma and Its Use in a Lymphocyte Blastogenesis Assay. Cancer Research 41:3000-3004, 1981.

127. Valli, V.E., B.J. McSherry, B.V. Dunham and R.M. Jacobs.

Histocytology of Lymphoid Tumors in the Dog, Cat and Cow. Veterinary Pathology 18:494-512, 1981.

128. Jacobs, R.M., V.E.O. Valli and B.N. Wilkie. Response of Cows with

Lymphoma to the Intradermal Injection of Tumor Cell Antigens and Phytohemagglutinin. Canadian Journal of Comparative Medicine 45:43-50, 1981.

129. Jacobs, R.M., V.E.O. Valli and B.N. Wilkie. Detection of Soluble

Tumor-Associated Antigen by Radioimmunoassay. Canadian Journal of Comparative Medicine 45:82-86, 1981.

130. Jacobs, R.M., M.G. Weiser, R.L. Hall and J.J. Kowalski.

Clinicopathologic Features of Canine Parvoviral Enteritis. Journal American Animal Hospital Association 16:809-814, 1980.

131. Jacobs, R.M., V.E.O. Valli and B.N. Wilkie. Serum Electrophoresis and

Immunoglobulin Concentration in Cows with Lymphoma. American Journal of Veterinary Research 41:1942-1946, 1980.

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132. Jacobs, R.M., V.E.O. Valli and B.N. Wilkie. Inhibition of Lymphocyte Blastogenesis by Sera from Cows with Lymphoma. American Journal of Veterinary Research 41:372-376, 1980.

133. Wilkie, B.N., F. Caoilli and R.M. Jacobs. Bovine Lymphocytes:

Erythrocyte Rosettes in Normal, Lymphomatous and Corticosteroid-Treated Cattle. Canadian Journal of Comparative Medicine 43:22-28, 1979.

Papers in refereed conference proceedings

1. Jacobs R.M. Studies of bovine lentivirus infection in sheep. Australian

Center for International Agricultural Research and the Ministry of Agriculture, Indonesia. “Jembrana Disease in Indonesia”. Bali, Indonesia, June 1996.

Papers Read at Scientific Conferences

1. Qurioz-Rocha GF, LeBlanc S, Duffield T, Wood RD, Leslie KE, Jacobs RM. Serum cholesterol and fatty acid concentrations as predictors of retained placenta in dairy cows. 24th World Buiatrics Congress, Nice, France, October, 2006

2. Qurioz-Rocha GF, LeBlanc S, Duffield T, Wood RD, Leslie KE, Jacobs

RM. Serum cholesterol and fatty acid concentrations as predictors of retained placenta in dairy cows. 39th Annual Convention of the American Association Bovine Practitioners, St. Paul, MN, Sep, 2006.

3. Burgess HJ, Woods JP, Ogg ACG, Jacobs RM, Wood RD. Use of a

collagen binding assay and platelet function analyzer in the characterization of dogs with von Willebrand disease. 56th Annual meeting of the American College of Veterinary Pathologists, Boston, MA, 2005.

4. Keller SL, Wood RD, Jefferson BJ, Jacobs RM. The effects of

noncytopathic type 2 bovine viral diarrhea virus on bone marrow stem cell proliferation. 3rd Annual Meeting of the Canadian Animal Health Laboratorians Network, Guelph, ON, 2004.

5. Harvey, S.J., Zheng, K., Jefferson, B., Moak, P., Sado, Y., Naito, I.,

Ninomiya, Y., Jacobs, R.M., and Thorner, P.S. Transfer of the α5(IV) collagen chain gene to smooth muscle restores in vivo expression of the α6(IV) collagen chain in a canine model of Alport syndrome. American Society of Nephrology, Nov. 2002.

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6. Zheng K, Harvey SJ, Chen D, Jefferson B, Jacobs RM, Thorner PS. Global gene expression profiling in a canine model of X-linked Alport syndrome: Cross-species cDNA microarray analysis provides insight into the early molecular alternations associated with the onset of this progressive renal disease. Human Genome Meeting 2002 Workshop. Shanghai, China, 2002.

7. Abrams-Ogg, A., West, K.H., Norris, A.M., Woods, J.P., Bienzle, D.,

Jacobs, R.M., Ottewell, G., Stewart, K.J., and Kruth, S.A. Half-body radiation therapy versus maintenance chemotherapy for the treatment of dogs with multicentric lymphoma in remission: investigation of prognostic factors. Veterinary Cancer Society, Galena, Illinois, April, 2002.

8. Wood, D., D. Goens, S. Carman, D. Deregt, G. Nayar, R. Jacobs.

Pathogenesis of leukopenia in calves with type II noncytopathic bovine viral diarrhea virus. Canadian Veterinary Medical Association, Calgary, Alberta, Aug. 1999

9. VanDenHeuvel, M., R. Jacobs, D. Portetelle, B. Jefferson. Isolation of a

plasma protein which inhibits transcription of BLV in infected lymphocytes. Dairy Farmers of Ontario, May 1999.

10. Boyonoski, A.C., L.M. Gallacher, M.M. ApSimon, R.M. Jacobs, D.M. Shah,

G.G. Poirier, and J.B. Kirland. The effect of niacin deficiency in rats on ethylnitrosourea-induced anemia and leukopenia. 16th International Congress of Nutrition. Montreal, Canada, 1997.

11. Boyonoski, A.C., M.M. ApSimon, L.M. Gallacher, R.M. Jacobs, D.M. Shah,

G.G. Poirier, and J.B. Kirkland. The effect of niacin deficiency in rats on ethylnitrosourea-induced anemia, leukopenia, and cancer. 12th International Symposium on ACP-Ribosylation Reactions, Cancun, Mexico. 1997

12. Abed, Y., G. St.-Laurent, F. Denis, R. Jacobs, and D. Archambault.

Immunological reactivity of the bovine immunodeficiency virus capsid protein p26 and envelope protein gp42 expressed from baculovirus. Conference of Research Workers in Animal Diseases. Chicago, November, 1997.

13. Lumsden, J.L., R.M. Jacobs, M. O=Grady and R. Horne. Initial

assessments of a canine thyroid hormone stimulating assay. VIIth ISACB Congress, Glasgow, Scotland, July 1996

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14. Jacobs, R.M. Studies of bovine lentivirus infection in sheep. Australian Center for International Agricultural Research and the Ministry of Agriculture, Indonesia. AJembrana Disease in Indonesia@. Bali, Indonesia, June 1996.

15. Jacobs, R.M. An overview of the bovine retroviruses, Korean Veterinary

Research Congress, Chonbuk National University, Chonju, Korea, October, 1995

16. Thorner P., K. Zheng, R.M. Jacobs, R. Kalluri and B.G. Hudson. X-linked

hereditary nephritis in Samoyed dogs: A model for human X-linked hereditary nephritis. Seventh International Symposium on Basement Membranes. National Institutes of Health, Bethesda, Maryland, June, 1995.

17. Thorner, P., K. Zheng, R. Baumal, R. Jacobs, R. Kalluri and B.G. Hudson. X-Linked hereditary nephritis (HN) in Samoyed dogs: A model for human x-linked HN. Third International Workshop on Alport Syndrome. Erlangen, Germany, September 1994.

18. Dubé, I.D., Kamel-Reid, S., Kruth, S.A., Bienzle, D., Abrams-Ogg, A.C.G.,

Carter, R.F., Dick, J.E., Ackland-Snow, J. and Jacobs, R.M. Gene transfer into canine hematopoietic progenitors in long-term marrow cultures. Journal of Cellular Biochemistry. Suppl. 17E:SZ206, p230, 1993

19. Dubé, I.D., Kamel-Reid, S., Kruth, S.A, Bienzle, D., Abrams-Ogg, A.C.G.,

Carter, R.F., Dick, J.E., Ackalnd-Snow, J. and Jacobs, R.M. Retrovirally mediated transfer of a reporter gene into canine pluripotent hematopoietic progenitors; gene transfer and expression without selection or marrow ablative conditioning. American Journal of Human Genetics 51:A213, 1992.

20. Dubé, I.D., S. Kamel-Reid, S.A. Kruth, D. Bienzle, A.C.G. Abrams-Ogg,

R.F. Carter, J.E. Dick, J. Ackland-Snow and R.M. Jacobs. Retrovirally mediated transfer of a reporter gene into canine pluripotent hematopoietic progenitors; gene transfer and expression without selection or marrow ablative conditioning. American Society of Human Genetics, Fall, 1992.

21. Bienzle, D. and R.M. Jacobs. Use of bone marrow culture in a cat with

polycythemia vera. American College of Veterinary Pathologists, San Diego, December 1992.

22. Poon, H., E. Jimenez, Z. Song, R.M. Jacobs. Detection of bovine

leukemia virus genome in infected cattle by polymerase chain reaction. Rossiter Research Conference, Lake Couchiching, Ontario, September, 1991.

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23. Rand, J.S., J. Parent and R.M. Jacobs. Reference intervals for feline CSF. American College of Veterinary Internal Medicine Forum Proceedings, 1989.

24. Rand, J.S., J. Parent and R.M. Jacobs. CSF analysis in 61 cats with CNS

disease. American College of Veterinary Internal Medicine Forum Proceedings, 1989.

25. Jacobs, R.M., C.L. Swenson, D.J. Davenport and R.J. Murtaugh.

Changes in serum isoamylase activities with pancreatic and extra-pancreatic disease in the dog. American College of Veterinary Internal Medicine, May, 1987.

26. Fingeroth, J.M., D.D. Smeak and R.M. Jacobs. Intravenous methylene

blue infusion for intraoperative identification of parathyroid gland and pan-creatic islet cell tumors in dogs. American College of Veterinary Surgeons, February, 1987.

27. Jacobs, R.M. and J.H. Lumsden. A comparison of wet and dry reagent

chemistry analyzers in canine, feline, bovine and equine sera. Twenty-third World Veterinary Congress, Montreal, 1987.

28. Murtaugh, R.J. and R.M. Jacobs. Serum isoamylase activity in dogs with

various diseases. American College of Veterinary Internal Medicine, May, 1986.

29. Swenson, C. and R.M. Jacobs. Cyclic hematopoiesis in FeLV infected

cats. Veterinary Cancer Society, April, 1986.

30. O'Keefe, D.A., C.G. Couto, C. Burke-Schwartz and R.M. Jacobs. Canine systemic mastocytosis. Veterinary Cancer Society, Spril, 1986.

31. Heeney, J., R.M. Jacobs and V.E.O. Valli. Antibodies to cell surface

proteins of enzootic bovine lymphoma not detected in allogenous or autogenous sera. 1st International Veterinary Immunology Symposium, July, 1986.

32. Heeney, J., R.M. Jacobs and V.E.O. Valli. Increased prevalence and

severity of concurrent disease in rabbits infected with bovine leukemia virus. 1st International Veterinary Immunology Symposium, July, 1986.

33. Jacobs, R.M., C.G. Couto and J. Cornacoff. The distribution and binding

of lectins to normal and neoplastic lymphoid tissue in the dog. 1st International Veterinary Immunology Symposium, July, 1986.

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34. Davenport, D.J., R.G. Sherding and R.M. Jacobs. Ammonia tolerance test: Comparison of three methods of ammonia administration. American College of Veterinary Internal Medicine Scientific Meeting, June, 1985.

35. Murtaugh, R.J. and R.M. Jacobs. Serum antiprotease activity in dogs with

experimentally induced pancreatitis. American College of Veterinary Internal Medicine Scientific Meeting, May, 1984.

36. Seide, R.K., R.M. Jacobs and J.M. Kehoe. Isolation and characterization

of a homogeneous euglobulin from the serum of a horse with a spontaneous multiple myeloma syndrome. Abstract No. 140. Federation American Society Experimental Biology 41: 292, 1982.

37. Valli, V.E., B.J. McSherry, R.M. Jacobs, B. Dunham and J.H. Lumsden.

Leukemia in dogs and cats. A histocytologic study on the lymphosarcomas. Proceedings Twentieth World Veterinary Congress. Thessaloniki, 1975.

Poster Presentations at Scientific Conferences

1. Neta, M., Katavolos, P., DeLay, J., Wood, R.D., Moore, P.F. and Jacobs, R.M. In situ characterization of productive cytotoxicity in tumor infiltrating lymphocytes of a naturally occurring, self-regressing canine tumor. 62cd Annual Meeting of the American College of Veterinary Pathologists, Nashville, Nov. 2011.

2. Neta, M., Wood, R.D., Moore, P.F., and Jacobs, R.M. Canine

hemophagocytic histiocytic sarcoma, a potential naturally occurring model for familial hemophagocytic lymphohistiocytosis. 62cd Annual Meeting of the American College of Veterinary Pathologists, Nashville, Nov. 2011.

3. Neta, N., Katavolos, P., DeLay, J., Wood, R.D., Moore, P.F., and

Jacobs, R.M. The role of perforin in the regression of canine cutaneous histiocytoma. 61st Annual Meeting of the American College of Veterinary Pathologists, Baltimore, Nov. 2010.

4. Burgess, H., Woods, J.P., Ogg, A.C.G., Jacobs, R.M., and Wood, R.D. The use of a questionnaire and a von Willebrand Factor Diagnositc Profile to evaluate risk and signs of hemorrhage in normal dogs and dogs with von Willebrands disease. American College Veterinary Internal Medicine. 2007.

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5. Perry, J.A. Ackerley, C., Ho, M., Zheng, K., Viero, S., Jacobs, R.M., and Thorner, P.S. The intermediate filment nestin is highly expressed in normal human podocytes and podocytes in glomerular disease. American Society of Nephrology, 2006.

6. Quiroz-Rocha GF, Duffield T, LeBlanc S, Leslie KE, Wood RD, Jacobs

RM. Biochemical and hematological values in pre and postpartum dairy cows. Graduate Student Appreciation Day, OVC, University of Guelph, 2006

7. Quiroz-Rocha GF, Duffield T, LeBlanc S, Leslie KE, Wood RD, Jacobs

RM. Biochemical and hematological values in pre and postpartum dairy cows. American College of Veterinary Pathologists, Dec 2005

8. Keller SL, Jefferson BJ, Jacobs RM, Wood RD. The effects of

noncytopathic type 2 bovine viral diarrhea virus on bone marrow colony forming unit – granulocyte-macrophage (CFU-GM) progenitor cells. American College of Veterinary Pathologists, Dec 2005

9. Chesterfield PK, Magda S, Keller SL, Jefferson BJ, Jacobs RM, Wood

RD. Apoptosis in bone marrow cells of calves experimentally infected with noncytopathic type 2 bovine viral diarrhea virus. American College of Veterinary Pathologists, Dec 2005

10. Burgress HJ, Woods JP, Ogg ACG, Jacobs RM, Wood RD. Use of a

collagen binding assay and platelet function analyzer in the characterization of dogs with von Willdebrand disease. American College of Veterinary Pathologists, Dec 2005

11. Magda SA, Wood RD, Jefferson BJ, Jacobs RM. Evaluation of a low

virulence noncytopathic type 2 BVDV isolate as a vaccine candidate. OVC Summer Leadership and Research Program, Guelph, Aug 2005

12. Perry J, Zheng K, Jefferson B, Sado Y, Jacobs R, Thorner P. Collagen

IV NC1 hexamers can induce partial differentiation of bone marrow stem cells along a podocyte lineage. American Society Nephrology, Nov 2004.

13. Keller SL, Wood RD, Jefferson BJ, Jacobs RM. The effects of

noncytopathic type 2 bovine viral diarrhea virus on bone marrow stem cell proliferation. American College of Veterinary Pathologists, Nov 2004.

14. Wood RD, Chesterfield PK, Jefferson BJ, Jacobs RM. Evaluation of

apoptosis in bone marrow of calves experimentally infected with

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noncytopathic type 2 bovine viral diarrhea virus. Conference Research Workers in Animal Disease, Chicago, Nov 2004.

15. Perry J, Zheng K, Harvey S, Tam S, Pedchenko V, Chen D, Jacobs

RM, Hudson BG, Thorner PS. Alport and normal NC1 hexamers are equally permissive to podocyte growth and differentiation. American Society of Nephrology, Nov 2003.

16. Keller SL, Wood RD, Jefferson BL, Jacobs RM. Evaluation of a

commercial methycellulose medium and recombinant bovine granulocyte colony-stimulating factor for culturing bovine bone marrow cells. American College of Veterinary Pathologists, Nov 2003.

17. Wood RD, Goens SD, Carman PS, Deregt D, Jefferson B, Jacobs RM.

Effects of experimental infection of calves with noncytopathic type 2 bovine viral diarrhea viruses on hematopoietic tissue. American College of Veterinary Pathologists, Nov 2003.

18. Tam, S., Harvey, S.J., Zheng, K., Jacobs, R.M., and Thorner, P.S.

Characterization of a podocyte cell line and its response to different extracellular matrices: A tool for understanding the pathogenesis of Alport Syndrome. Samuel Lunenfeld Summer Student Research Symposium, Hospital for Sick Children, May 2002

19. Zheng K, Harvey SJ, Chen D, Jefferson B, Jacobs RM, Thorner PS.

Global gene expression profiling in a canine model of X-linked Alport syndrome: Cross-species cDNA microarray analysis provides insight into the early molecular alterations associated with the onset of this progressive renal disease. Human Genome Meeting 2002 Workship. Shanghai, China 2002.

20. Van Den Heuvel, M., Jefferson, B., and Jacobs, R.M. Investigations

into the efffects of bovine plasma protein on cultured peripheral blood mononuclear cells. Canadian Society for Immunology, Collingwood, April 2002.

21. Wood, D., D. Goens, S. Carman, D. Derget, G. Nayar, and R. M.

Jacobs. Mechanisms of leukopenia in calves with type II non-cytopathic bovine viral diarrhea virus (BVDV). Dairy Farmers of Ontario Annual Meeting. Toronto, January 2002.

22. Harvey, S.J., Zheng, K., Chen, D., Jefferson, B., Jacobs, R.M., and

Thorner, P.S. Identification of differentially expressed genes in kidneys of dogs with X-linked Alport syndrome using cDNA microarray analysis. American Society of Nephrology, Nov. 2001.

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23. Zheng, K., Harvey, S.J., Sado, Y., Naito, I., Ninomiya, Y., Jacobs, R.M., and Thorner, P.S. Downregulation of the COL4A3 and COL4A4 genes in canine X-linked Alport syndrome is temporally and spatially regulated. American Society of Nephrology, Nov. 2001.

24. Chen, D., Jefferson, B., Harvey, S., Jacobs, R.M., and Thorner, P.S.

Cyclosporine A slows the progressive renal disease of X-linked Alport syndrome: Results from a canine model. American Society of Nephrology, Nov. 2001.

25. Harvey, S. Mount, R., Ninomiya, Y., Sado, Y., Naito, I., Harrison, R.,

Jacobs, R., and Thorner, P. Canine inner ear undergoes a developmental shift in type IV collagen associated with acquisition of high tone hearing: relevance to Alport=s syndrome. American Society of Nephrology, October 1999.

26. Harvey, S., Zheng K., Heikkila, P., Sado, Y., Naito, I., Ninomiya, Y.,

Jacobs, R., Tryggvason, K., and P. Thorner. Expression of recombinant alpha 5 (IV) collagen: Implications for collagen assembly and gene therapy in Alport=s syndrome. American Society of Nephrology, October 1999.

27. Zheng, K., S. Harvey, Y. Ninomiya, Y. Sado, I. Naito, R. Jacobs,

P.S. Thorner. Absence of the α6 chain of collagen type IV in Alport syndrome is related to a failure at the protein assembly level. American Society of Nephrology, October 1998.

28. Harvey, S., R. Mount, B. Lin, Y. Ninomiya, Y. Sado, I. Naito, R.

Harrison, R. Jacobs, and P.S. Thorner. Molecular basis for hearing loss in X-linked Alport syndrome: clues from the inner ear of dogs with X-linked nephritis. American Society of Nephrology, October 1998.

29. Harvey, S., Y. Ninomiya, Y. Sado, I. Naito, K. Zheng, R. Jacobs,

B.G. Hudson, and P.S. Thorner. Pathogenesis of canine X-linked nephritis involves the arrest of a developmental switch from an α1/α2 to an α3/α4/α5 collagen type IV network in glomeruli. American Society of Nephrology, November 1998

30. Harvey, S., K. Zheng, P. Heikkila, Y. Ninomiya, Y. Sado, I. Naito, R.

Jacobs, K. Tryggvason, and P. Thorner. Cloning and expression of canine α5 chain of collagen type IV - a step towards gene therapy in a model of Alport syndrome. American Society of Nephrology. November, 1998

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31. VanDenHeuvel, M., R.M. Jacobs, and D. Portetelle. Zeroing in on a plasma protein which inhibits expression of bovine leukemia virus. Conference of Research Workers on Animal Diseases. Chicago, Illinois, Novmber, 1998.

32. Wood, D., D. Goens, S. Carman, D. Derget, G. Nayar, and R. M.

Jacobs. Mechanisms of leukopenia in calves with type II non-cytopathic bovine viral diarrhea virus (BVDV). American College of Veterinary Pathologists, St. Louis, Missouri, November, 1998.

33. Goens, S.D., R.D. Wood, S. Carman, D. Deregt, G. Nayar, and R.M.

Jacobs. Haematological changes and postmortem findings in severe acute bovine viral diarrhea. Canadian Society for Microbiology, Guelph, Ontario, June, 1998.

34. VanDenHeuvel, M.J., R.M. Jacobs and D. Portetelle. Plasma protein

expression of bovine leukemia virus in cultured lymphocytes. United States and Canadian Academy of Pathology, Washington, March, 1998.

35. Grodecki K., M. Gains, R.M. Jacobs, R. Baumal, V. Valli, P. Thorner,

B. Osmond and B. Cotter. ACE inhibitor treatment of chronic renal failure in a canine model of hereditary nephritis. American College of Veterinary Pathologists, Atlanta, Georgia, November, 1995

36. Grodecki K.M., M.J. Gains, R.M. Jacobs R. Baumal, V. Valli, P.

Thorner, D. Osmond and B. Cotter. The effect of an angiotensin converting enzyme inhibitor on the progression of Samoyed Herediatry Glomerulonephritis. Annual Graduate Student Interuniversity Pathology Research Day. University of Toronto, June 1995.

37. Gains M., K. Grodecki, R. Jacobs, R. Baumal, V. Valli, P. Thorner,

D. Osmond and B. Cotter. ACE Inhibitor treatment of chronic renal failure in a canine model of hereditary nephritis. United States and Canadian Academy of Pathology, Toronto, Canada, March, 1995.

38. Jacobs, R.M., W.B. McNab, F.L. Pollari and B. Jefferson. A

serological survey of bovine syncytial virus in Ontario: Associations with bovine leukemia and immunodeficiency-like viruses, production records, and management practices. American College of Veterinary Pathologists. Montreal, Canada, December 1994.

39. Schnurr, M.W., R.F. Carter, I.D. Dubé and V.E. Valli. Nonrandom

chromosomal abnormalities in bovine lymphoma. Eighth North American Colloquim on Animal Cytogenetics and Gene Mapping. University of Guelph, Guelph, Ontario, July, 1993.

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40. Smith, H.E., R.M. Jacobs and B. Mallard. Lymphocyte stimulation

response and immune function testing of sheep exposed to bovine immunodeficiency-like virus. Seventy-Third Conference of Research Workers in Animal Diseases, November 9-10, 1992.

41. Smith, H.E., R.M. Jacobs, C.A. Whetstone, V.E.O. Valli, B. Jefferson

and C. Davies. Serological, hematological, and lymphocyte subset responses of sheep experimentally inoculated with bovine immunodeficiency-like virus. Seventy-Third Conference of Research Workers in Animal Diseases, November 9-10, 1992.

42. Colbatzky, F. and R.M. Jacobs. Detection of retroviral-like elements

in genomic DNA of dogs with and without lymphoma. Seventy-Third Conference of Research Workers in Animal Diseases, November 9-10, 1992.

43. Bienzle, D., R.F. Carter, S. Kamel-Reid, J.E. Dick, S.A. Kruth, V.E.

Valli, R.M. Jacobs and I.D. Dubé. Gene transfer in the dog utilizing long-term bone marrow culture and a retroviral vector. American College of Veterinary Pathologists, Orlando, December 1991.

44. Smith, H.E. and R.M. Jacobs. Flow cytometric analysis of ovine

peripheral blood leukocytes. American College of Veterinary Pathologists, Orlando, December 1991.

45. Taylor, J.A., R.M. Jacobs and D. Portetelle. Effects of plasma and

serum on the in vitro expression of bovine leukemia virus. American College of Veterinary Pathologists, Orlando, December 1991.

46. Vernau, W., V.E. Valli, J.L. Heeney and R.M. Jacobs.

Immunophenotypic characterization of bovine lymphomas. American College of Veterinary Pathologists, Orlando, December 1991.

47. Jacobs, R.M., Z. Song, H. Poon, J.L. Heeney, J.A. Taylor, B.

Jefferson, W. Vernau and V.E. Valli. Host-virus interaction defined by proviral detection and serology in bovine leukemia virus infected normal cattle and cattle with lymphoma. American College of Veterinary Pathologists, Orlando, December 1991.

48. Jacobs, R.M., J.L. Heeney, M.A. Godkin, K.E. Leslie, J.A. Taylor, C.

Davies and V.E. Valli. Production and related variables in bovine leukemia virus infected cows. American College of Veterinary Pathologists, Orlando, December 1991.

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49. Jacobs, R.M., H. Smith, B. Gregory and C. Whetstone. Cross

reactivity of BIV and HIV proteins using bovine and human sera in a Western Blot Assay. American College of Veterinary Pathologists, Orlando, December 1991.

50. Jacobs, R.M., S.M. Cochrane, J.H. Lumsden and A.M. Norris.

Relationship of cerebrospinal fluid protein concentration determined by dye-binding and urinary dipstick methodologies. American Association of Clinical Chemistry - Animal Division, Washington, July 1991.

51. Jacobs, R.M., J.H. Lumsden, J.A. Taylor and E. Grift. Effects of

interferents on the kinetic Jaffé reaction and an enzymatic colorimetric test for serum creatinine concentration determination in cats, cows, dogs and horses. American Association of Clinical Chemistry - Animal Division, Washington, July 1991.

52. Grift, E., R.M. Jacobs and J.H. Lumsden. Precision and correlative

data for an in-clinic veterinary clinical chemistry analyzer (Clinstat). American Association of Clinical Chemistry - Animal Division, Washington, July 1991.

53. Jacobs, R.M., J.H. Lumsden and E. Grift. Comparison of isoelectric

focusing and levamisole-inhibition for determination of canine steroid-induced alkaline phosphatase activity. American Association of Clinical Chemistry - Animal Division, Washington, July 1991.

54. Jacobs, R.M., J.H. Lumsden and E. Grift. Effects of bilirubinemia,

hemolysis, and lipemia on clinical chemistry analytes in bovine, canine, equine and feline sera. American Association of Clinical Chemistry - Animal Division, Washington, July 1991.

55. Smith, H.E. and R.M. Jacobs. Augmentation of bovine

immunodeficiency-like virus production in long-term cultures of canine fetal thymus cells and infectivity of this virus in sheep. Canadian International Neuroscience Symposium, June 1989

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Invited Papers Presented at Professional Meetings and Continuing Education (ranging from 1 to 30 hr)

1. Update on the bovine retroviruses. (3 hr) Canadian Food Inspection Agency. Guelph, Ontario, May, 2005.

2. Update on the bovine retroviruses. (3 hr) Canadian Food Inspection

Agency. Guelph, Ontario, May, 2004.

3. Clinical pathology NAVLE review. (2 hr) Ontario Veterinary College, Guelph, Dec 2003

4. Canine model of Alport syndrome. (1 hr). Animal Renal Disease

Conference at College of Veterinary Medicine, National Autonomous University of Mexico, Mexico City, Jul 2003

5. Review of cytology, renal function testing, and urinalysis. (6 hr) College of

Veterinary Medicine, National Autonomous University of Mexico, Mexico City, Jul 2003

6. Update on the bovine retroviruses. (3 hr) Canadian Food Inspection

Agency. Guelph, Ontario, May, 2003

7. Clinical Biochemistry. (30 hours). Koret School of Veterinary Medicine. Part of clinical pathology course for second year veterinary students. Rehovot, Israel, January 2003.

8. Animal clinical biochemistry and endocrinology. (30 hr) Koret School of

Veterinary Medicine. A clinical pathology course for second year veterinary students. Rehovot, Israel, Jan 2003

9. A review of canine X-linked nephritis. (1 hr) Departmental seminar.

Guelph, Ontario, May 2002

10. Update on the bovine retroviruses. (3 hr) Canadian Food Inspection Agency. Guelph, Ontario, May, 2002

11. A review of canine X-linked nephritis. (1 hour) Departmental seminar.

Guelph, Ontario, May 2002. 12. Update on the bovine retroviruses. (3 hours) Canadian Food Inspection

Agency. Guelph, Ontario, May, 2002

13. Update on the bovine retroviruses. (3 hours) Canadian Food Inspection Agency. Guelph, Ontario, May, 2001

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14. Update on the bovine retroviruses. (3 hours) Canadian Food Inspection Agency. Guelph, Ontario, May, 2000

15. Update on the bovine retroviruses. (1.5 hours) Canadian Food Inspection

Agency. Guelph, Ontario, May, 1999

16. Update on the bovine retroviruses. (1.5 hours) Canadian Food Inspection Agency. Guelph, Ontario, May, 1998

17. Update on the bovine retroviruses. (1.5 hours) Canadian Food Inspection

Agency. Guelph, Ontario, May, 1997

18. Practical Research, Virus important even when it doesn=t cause disease. Ontario Farmer, April, 1997

19. Battling Bovine Leukemia Virus. Agri-food research in Ontario, June,

1996, p. 50

20. Applying cytology in your practice: when to use it, getting the sample, the cytologic approach to getting answer (1 hour). World Small Animal Veterinary Association, Jerusalem, October, 1996

21. Lesions the practitioner can confidently identify using cytology and Ahow to

communicate with your pathologist@ (1hour). World Small Animal Veterinary Association, Jerusalem, October, 1996

22. The numbers game -1, Roundtable discussion on laboratory data

interpretation utilizing cases with hematologic disease (1 hour). World Small Animal Veterinary Association, Jerusalem, October 1996

23. The numbers game -2, Roundtable discussion on laboratory data

interpretation utilizing cases with clinical chemistry abnormalities (1 hour). World Small Animal Veterinary Association, Jerusalem, October 1996

24. Laboratory tour and display on behalf of the Pet Trust: Pet Trust Forum (2

hours). Ontario Veterinary College, June, 1996

25. A seminar series on clinical laboratory data interpretation (4 hours), Genesee Valley Veterinary Medical Association, Rochester, New York, May, 1996

26. A series of lectures in clinical pathology (4 hours), College of Veterinary

Medicine, Chonbuk National University, Chonju, Korea, October, 1995

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27. Overview of bovine retroviruses (1 hour), Ontario Milk Marketing Board (Dairy Farmers of Ontario) Annual Meeting, University of Guelph, June, 1995

28. Bovine retroviruses (0.5 hours), Barbara Graham Symposium on

Veterinary Cancer Medicine, University of Guelph, June, 1995

29. Review of bovine retroviruses (1.5 hours), Agriculture and Agri-Food Canada Professional Update Course, University of Guelph, May, 1995.

30. Cytology Wet Labs for veterinarians (7 hours). Lifelearn Inc, Guelph,

Ontario, November, 1994

31. Case discussions in clinical chemistry and hematology for veterinarians(4 hours). Lifelearn Inc, Guelph, Ontario, Sept, 1994

32. Case discussion in clinical chemistry and hematology. (5 hours) Koret

Veterinary School, Hebrew University, April, 1994.

33. Practical Cytology - Wet Lab (8 hours in 2 sessions). Israel Small Animal Veterinary Medical Assocation, Koret Veterinary School, Hebrew University, April, 1994

34. Pathogenesis of bovine leukemia virus infections in cattle (1 hour). Kimron

Veterinary Institute, Beit Dagan, Israel, April, 1994.

35. Cytology for the practitioner with case examples (4 hours). Israel Small Animal Veterinary Medical Assocation, Koret Veterinary School, Hebrew University, April, 1994.

36. Pathogenesis and diagnosis of anemia with case examples (4 hours).

Israel Small Animal Veterinary Medical Assocation, Koret Veterinary School, Hebrew University, April, 1994.

37. Pathogenesis and diagnosis of anemia (2 hours). Koret Veterinary School,

Hebrew University, Israel, January, 1994.

38. Review of Cytology (2 hours). Koret Veterinary School, Hebrew University, Israel, January, 1994

39. Urinalysis (2 hours). Koret Veterinary School, Hebrew University, Israel,

January, 1994.

40. Evaluation of hepatocyte integrity and hepatic function. Manual of Clinical Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

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41. Water, electrolyte, and acid-base disorders. Manual of Clinical Pathology:

A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993

42. Renal system: glomerular and tubular function. Manual of Clinical

Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

43. Anemia - Diagnostic approach and classification. Manual of Clinical

Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993

44. Leukocyte changes in non-neoplastic diseases. Manual of Clinical

Pathology: A Symposium for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

45. Cytology for the practitioner. Manual of Clinical Pathology: A Symposium

for Veterinarians, Post Graduate Committee in Veterinary Science, University of Sydney, February, 1993.

46. Review of bovine retroviruses (2 hours). College of Veterinary Medicine,

University of Prince Edward Island, April, 1993.

47. Review and Update on Veterinary Clinical Pathology (30 hours). Postgraduate Committee in Veterinary Science, University of Sydney, February, 1993.

48. Review of bovine retroviruses (2 hours), Agriculture Canada Professional

Update Course, University of Guelph, May, 1993.

49. Research seminar on Studies in Bovine Retroviruses (2 hours). Animal Diseases Research Institute, Ottawa, Ontario, January, 1992.

50. Basic Cytological Interpretation (3 hours), Companion Animal Certificate

Series, June 1992.

51. Research seminar on Bovine Immunodeficiency-Like Virus (2 hours). Parke-Davis Research Institute, Mississsauga, Ontario, February, 1992.

52. Companion animal certificate series. Seminars in the interpretation of

clinical chemistry data (2 hours). University of Guelph, May, 1992.

53. Companion animal certificate series. Wet lab in advanced interpretation of cytologic preparations (3 hours). University of Guelph, June, 1992.

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54. Review of bovine retroviruses (2 hours). Canadian Department of Agriculture Veterinary Professional Update Course. University of Guelph, May, 1992.

55. Companion animal certificate series. Interpretative hematology and

clinical chemistry (3 hours). University of Guelph, May, 1991.

56. Slide review of hemolymphatic system (1 hour). University of Guelph, Department of Pathology. March 1990.

57. Bovine immunodeficiency-like virus (1 hour). Veterinary Laboratory

Services Branch Annual Scientific Meeting. February 1990

58. Tissue factors influencing the in vitro expression of bovine leukemia virus (presented by J. Taylor), Canadian Association of Veterinary Pathologists, Halifax. July 1990

59. Comparison of clinical chemistry results obtained using the Ektachem and

DACOS instruments (1 hour). Winter 1989.

60. Serum iron concentration and iron binding capacity in normal dogs (1 hour). Winter 1989.

61. Immunological resistance to tumors (2 hours). Advances in Immunology

(Graduate Course, 91-611). April 1989.

62. Review of cytology (2 hour), OVC Small Animal Club. February 1989.

63. Comparison of FeLV test kits for Norden Laboratories. January 1989.

64. Cytology for the practitioner (1 hour lecture, 3 hour wet lab), OVC Annual Fall Conference. September 1988.

65. Review of FeLV and FIV diagnosis (1 hour), OVC Annual Fall Conference.

September 1988.

66. Prevalence of bovine immunodeficiency virus-infected cattle and associations with Bovine Leukemia Virus infection, persistent lymphocytosis, and lymphoma (1 hour). Presentation to Ontario Cattlemen's Association, University of Guelph, Guelph, Ontario, June 1988.

67. VMIMS used in Teaching and Research. OVC Computer Group.

University of Guelph, Guelph, Ontario, March 1987.

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68. Molecular biology of the Bovine Leukemia Virus (1 hour). Molecular Biology Club, University of Guelph, Guelph, Ontario, February 1987.

69. Pancreatitis in dogs (1 hour). Columbus Emergency Veterinary

Association. Columbus, Ohio. July, 1984.

70. Three Afternoons of Hematology (12 hours). Columbus, Ohio. June 9, 16 and 30, 1984.

71. Erythrocyte and leukocyte changes with disease in cattle (3 hours). Bovine

Practitioners Workshop, Columbus, Ohio. August, 1982.

72. Practical hematology (3 hours). Stark County Veterinary Association, Canton, Ohio. May, 1982.

73. Clinicopathologic features of canine parvoviral enteritis (1 hour). College

of Veterinary Medicine Alumni Conference, Ohio State University. June, 1982.

74. Hematology and blood chemistry in the boa constrictor. Phi Zeta

presentation by Richard Funk and Carol Furman, freshmen veterinary students. April 1982.

75. Vaginal cytology in the mare. Phi Zeta presentation by William Regan,

senior veterinary student. April 1982

76. Equine cytology - An autotutorial. Ohio State University. February, 1981

77. A review of bovine lymphoma - An autotutorial. Ohio State University. March, 1981.

78. Cytologic diagnosis of subcutaneous masses (2 hours). Ohio Veterinary

Association, Columbus, Ohio. January 1981.

79. Hematology and blood chemistry in well and sick animals (3 hours). Interpretation of results. Equine Practitioners Workshop, Columbus, Ohio. January, 1981.

80. Cancer Clinic, Henderson General Hospital. Comparative pathology of

animal lymphomas and immunologic detection of bovine lymphoma (1 hour). The Ontario Cancer Foundation, Hamilton, Ontario. September, 1979.

81. Immunologic studies in bovine lymphosarcoma (1 hour). Canadian

Association of Veterinary Pathologists, Quebec City, Quebec. June 17, 1979.

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82. Practical hematology for the bovine practitioner (2 hours). Bovine

Practitioners Club, Toronto, Ontario. April 28, 1979.

83. General hematology: A series of four, 3 hour sessions to Animal Health Technologists, Centralia College. March 1979.

84. Ontario College Holstein Breeders Club. Bovine lymphoma: Course,

nature of the disease and methods of detection and prevention (2 hours). Manchester, Ontario. January 1979.

85. Bovine Practitioners Club. Bovine lymphoma: Immunologic mechanisms of

detection (1 hour). Guelph. September 1978.

Service From January 1996 I was a member of a joint committee looking at the amalgamation of the laboratory services offered by the OVC and the Veterinary Laboratory Services Branch of the Ontario Ministry of Agriculture, Food, and Rural Affairs. The committee met almost weekly. The merged lab began operation in April 1997. In January 1995, I became the Laboratory Co-ordinator for the College and in that role I meet once a week or once every other week for two hours with the Joint Veterinary Teaching Hospital Executive Committee. From Spring 1986 until April 1997, I was the Service Chief of the clinical pathology laboratory. In this capacity I was responsible for all facets of the day-to-day operation of the laboratory.

I served as supervisor of the Clinical Immunology Laboratory during July/August 2001 to assist during vacation.

International involvement and research leave

I have been invited to speak and interact with researchers and professional organizations in Australia, Indonesia, United States, Mexico, Middle East, and Korea. This has often been for my interests in the area of the bovine retroviruses and various areas in clinical pathology. I have co-operative research programs with researchers in Canada and the United States in the areas of the bovine retroviruses and hereditary nephritis. My research in BVDV involves collaborators in Canada, United Kingdom and the United States. I was on research leave from the beginning of January 1994 until the end of June 1994 as a Visiting Research Scientist at the Kimron Veterinary Institute

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and the Koret Veterinary School which is part of the Faculty of Agriculture at the Hebrew University. The time was primarily spent in preparing manuscripts and grant applications and interacting with pathologists and research scientists at the Institute and the Weizmann Institute in Rehovot in the field of the bovine retroviruses.

I had a research leave from 1 July 2002 to 1 July 2003. I remained on-site at the University of Guelph. This was spent attending conferences, writing manuscripts and grant applications and updating teaching materials.

Scholarly and Professional Activities External grant reviewer, Canadian Institutes of Health Research, 2007 Ad hoc reviewer of faculty, Tenure and Promotions, University of California at Davis, 2006 External examiner, PhD examination, Department of Veterinary Biology and Biomedical Sciences, School of Veterinary and Biomedical Studies, Murdoch University of Western Australia, 2005 Student advisor, North American Free Trade Association, Student exchange, Spring 2002 External grant reviewer, Saskatchewan Health Services Utilization and Research Commission, 2002 Ad hoc reviewer, Viral Immuology, 2002 Distinguished Teacher Award, Pfizer/Carl J. Norden,, 1999/2000 Teacher of the Year, Students of the Canadian Veterinary Medical Association, 1999

Reviewer of faculty, Tenure and Promotions, The University of Saskatchewan, Saskatoon, Saskatchewan, 1998 Ad hoc reviewer of faculty, Tenure and Promotions, University of Illinois, Urbana-Champaign, 1998

1998, Reviewer of faculty, Tenure and Promotions, The University of Saskatchewan, Saskatoon, Saskatchewan 1998, Reviewer of faculty, Tenure and Promotions, Michigan State University, East Lansing

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1996, Reviewer for two research proposals for the American Kennel Club/Canine Health Foundation 1996, Reviewed and rewrote the constitution and by-laws of the International Society for Animal Clinical Biochemistry in consultation with board members 1995, Reviewer of faculty for promotion and tenure for the State of Israel, Ministry of Agriculture, The Volcani Center 1995, Ad hoc reviewer of faculty for Department of Biological Sciences, Mississippi State University 1995, Proctor for part C (CPE) of the examination for the National Examining Board 1994, Member and part of the Organizing Committee for the VIth Congress of the International Society for Animal Clinical Biochemistry held at the University of Guelph 1994, Reviewer for the United States - Israel Binational Agricultural Research and Development Fund 1993, Reviewer of faculty, Tenure and Promotions, Royal College of Pathologists, London, England Ad hoc reviewer of faculty, Tenure and Promotions, The University of Queensland, Brisbane, Australia, 1992 1992 – 93, Member and Vice-Chairman of the Veterinary Laboratory Standards Committee 1992 – 93, Vice-Chairman of the Veterinary Laboratory Standards Committee for the American Society of Veterinary Clinical Pathology 1990, Reviewer of faculty, Tenure and Promotions, Tufts University, School of Veterinary Medicine, MA. 1992, Reviewer of faculty, Tenure and Promotions, The University of Queensland, Brisbane, Australia 1989, Member and Committee Chairman, Scientific Program Committee for the Vth International Symposium of the World Association of Veterinary Laboratory Diagnosticians held at the University of Guelph

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1989 – present, Member, Editorial Board for Seminars in Veterinary Medicine and Surgery (Small Animal) 1988 – 92, Member, Examination Committee, American College of Veterinary Pathologists 1988 – 98, Member, Editorial Board for Journal of Veterinary Clinical Pathology 1988, Ontario Graduate Scholarship Program, Section Leader 1987, External Examiner, PhD Examination Committee, University of Saskatchewan, Saskatoon 1987, Ontario Graduate Scholarship Program, Committee Member 1987, Proctor, American College of Veterinary Pathologists Examination Committee

Ad hoc reviewer for Digestion, 1987 and 1988

1986 – 90, Departmental Representative for Guelph Chapter of Sigma Xi

Adjunct faculty at The Ohio State University, College of Veterinary Medicine, 1985-1988

Ad hoc reviewer for Canadian Veterinary Journal, 1985 to present Ad hoc reviewer for Veterinary Pathology, 1984 to present

Ad hoc reviewer for Journal of the American Veterinary Medical Association, 1983 to present

Ad hoc reviewer for Journal of Veterinary Clinical Pathology, 1982 to present

Ad hoc reviewer for American Journal of Veterinary Research, 1982 to present

Ad hoc reviewer for Canadian Journal of Veterinary Research (formerly Canadian Journal of Comparative Medicine) , 1980 to present

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Professional Development Activities

1. Attendance at the annual meetings of the American College of Veterinary Pathologists and the American Society for Veterinary Clinical Pathology, 1980 to present.

2. Attended short course on immunopathology given by the International

Academy of Pathology, 1980

3. Attended seminars on grant preparation, MRC and NSERC, University of Guelph, Fall, 1987.

4. Attended Seventh Summer Symposium in Molecular Biology, Viruses:

Pathogens and Model Systems, Pennsylvania State University, July, 1988.

5. Attended Ninth Summer Symposium in Molecular Biology. Molecular

Pathways of Cell Growth Control, Pennsylvania State University, July, 1990.

6. Attended short course on Concepts in Molecular Biology given by the

International Academy of Pathology, Bethesda, 1992.

7. Attended conference on the Comparative Pathobiology of Lentiviruses given by the Registry of Comparative Pathology, Bethesda, 1993

8. WedCT training session. May 2001

9. Attended conference on Advances in Cytology, Harvard Medical School,

June 2002

Participation on University, College, and Departmental Committees

Year(s)

Name of Committee

University, College

or Department

Position Within Committee

2003-2008

Biosafety Committee

University

Chair

2001-02

Biosafety Committee

University

Member

2001-02

Department Awards Committee

Department

Member

2001-02

Pathobiology Chair Search Committee

College

Member

2001-present

DVM Admissions Committee

College

Member

2000-02

Animal Care Services Advisory Committee

University

Member

1998-02

University Appeals Committee

University

Member

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1997-98

Companion Animal Research Sub-Committee

College

Chair

1998-99

OMAFRA Dairy Research Section Committee

University

Member

1995-97

Companion Animal Research Sub-Committee

College

Member

1995-97

Departmental Committee

Department

Member

1996

Parasitology Search Committee

Department

Member

1996

Pathobiology Chair Search Committee

College

Member

1996

OVC/VLS Joint Committee on Amalgamating Lab

Services

Inter-institution

Member

1995-96

VLS/OVC Committee to Review Laboratory

Services

Inter-institution

Co-Chair

1995-96

OMAFRA Dairy Research Section Committee

University

Member

1995-96

Pathology/VMI Merger Committee

College

Member

1995-00

VTH Joint Executive Committee

College

Member

1993

Departmental representative for DVSc evaluation

University

Member

1992-94

Departmental Committee

College

Member

1992-94

Joint Job Evaluation Committee

University

Member

1992

Selection Committee for Associate Dean

College

Member

1992

Selection Committee for Pathology Chair

College

Member

1992

Committee to review out-of-hours and wknd duty

for pathologists

Department

Member

1991

Selection Committee for Director of College

Computer Group

College

Member

1989-00

Mentor Program and Externship

College

Member

1988-92

Departmental Safety Officer

Department

Chairperson

1988-92

Companion Animal Res. Subcommittee

College

Chairperson

1988-90

Departmental Committee

Department

Member

1988

Dairy Research Priorities Committee

College

Member

1986-88

Area Co-ordinator & Service Chiefs

College

Member

1986-87

Companion Animal Res. Subcommittee

College

Member

1986-present

Medical Records Committee

College

Member

1986-87

Departmental Committee

Department

Member

1986-87

Academic Plan Committee

Department

Member

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1986-87

Teaching Evaluation Committee

Department

Chairperson

1987-88

Committee to Evaluate, Review Graduate Courses

and Implement New Graduate Courses

Department

Chairperson

1982-85

Medical Records Committee

College

Member

1984

Committee to Assess Feasibility of Equine Bood

Typing Lab.

College

Member

1980-85

Service and Safety Committee

Department

Member

1983-85

Equine Research Fund Rev. Committee

College

Member

1983-85

Computer Utilization Committee

College

Member

1984-85

Long Range Planning Committee

College

Member

Robert M. Jacobs 16 Feb 2016