Department of Nuclear Medicine & PET-CT

Radionuclides for Human wellbeing

Facilities Available● PET-CT (Siemens True point Biograph

mCT-40 slice CT)- India’s first Ultra HD PET-CT.

● SPECT Gamma Camera (GE Millennium MG)

● Radioiodine Therapy Ward for treatment of Thyroid Cancer patients.

PET-CT POSITRON EMISSION TOMOGRAPHY

MOLECULAR IMAGING IN COMPREHENSIVE CANCER CARE

MINIMUM DOSE MAXIMUM SPEED INDIA’S FIRST ULTRA HD PET-CT

PET - CT

ONE STOP SHOP FOR CANCER CARE ANATOMETABOLIC DIAGNOSIS

EARLY DETECTION DEFINES THE SEVERITY & EXTENT

SURVEYS ENTIRE BODY IN A SINGLE STUDY

PET-CT Anato-metabolic imaging

CT SCAN PET SCAN FUSION

PET – CT Applications in Oncology

● Diagnosis ● Staging● Treatment Response● Restaging● Radiotherapy Planning ● Guiding Biopsy in a wide range of Cancers.

Breast Cancer Detection / Staging

Very early prediction of responseto chemotherapy & change of chemotherapy

Carcinoma lung - Treatment response monitoring Before Chemotherapy

After Chemotherapy

Metabolicresponse

BRAIN TUMOR RECURRENCE

DIAGNOSING UNKNOWN CANCER

Liver lesions on CT scan? Metastases or Hepatoma PET CT DIAGNSOED COLONIC CANCER WITH LIVER SECONDARIES

PET DIRECTED BIOPSYMinimizing sampling error

Treatment planning: Better Tumor Definition

Dose painting

Cut andPaste theRT dose

•IMRT•IGRT

Give maxdose to tumorwhere it isproliferating more

NONONCOLOGICAL APPLICATIONS OF PET - CT

Cardiology:• Assesment of Myocardial viability

Neurology:• Epilepsy• Neurodegenerative disorders• Anxiety & depressive disorders.

CARDIAC PET-CTASSESMENT OF VIABILITY

INFECTION LOCALIZATION / EXTENT

Alzheimer’s Disease

• EARLY DIAGNOSIS OF MILD COGNITIVE IMPAIREMENT

• DIFFERENTIATES VARIOUS CAUSES OF MEMORY LOSS

Multiinfarct dementia

SEIZURE FOCUS LOCALIZATION A case of Left MTS

Gamma Camera

Nuclear Medicine & PET-CT

Dual Head Gamma Camera (Millennium MG)

● Radiopharmaceuticals are organ specific chemical compounds combined with radionuclides.

● These radiopharmaceuticals, once administered to the patient, localize to specific organs or cellular receptors which allows us to image the extent of a disease-process in the body, based on the cellular function (Physiology), rather than relying on physical changes in the tissue anatomy.

Dual Head Gamma Camera (Millennium MG)

Application

Functional/Physiological imaging of various Organs/Organ systems

BONE SCAN

● Highly sensitive● Surveys entire body in

a single study● Diagnoses the lesion

earlier than radiograph

EARLYDiagnosis of bone secondaries in a cancer patient

BONE SCAN

THYROID SCAN

Provides the Uptake Function of Thyroid Gland

Detectes Nonfunctioning Nodules (30% of Which Could be Cancerous )

Differentiates Hyperthyroidism Causes

Thyroid Scan Graves’ Disease

Curable with Radioiodine Therapy

● Patient Presented with Thyroid Swelling

● Thyroid Scan Shows Nonfuntioning Nodule

● Biopsy Revealed Thyroid Cancer

● Complete Cure for Thyroid Cancer at early stage (Papillary & Follicular Varieties) is Possible with Surgical Removal of Thyroid Gland with

Neck Lymphnode Dissection

Followed By High Dose Radioiodine Therapy

Comprehensive Cancer Care Under One Roof

RENAL SCAN FUNCTIONAL IMAGING OF RENAL SYSTEM GIVES ACCURATE FUNCTIONAL STATUS ( GFR) RULES OUT URINE OUTFLOW OBSTRUCTION

IN THE RENAL SYSTEM DIAGNOSE INFECTION AT THE EARLIEST EARLY DETECTION OF KIDNEY TRNASPLANT

COMPLICATIONS EVALUATION OF ACCELERATED

HYPERTENSION (CAPTOPRIL RENOGRAM)

DTPA Renal Scan Left PUJ Obstruction

PYELONEPHRITIS INFECTED SCARRED KIDNEYS

MYOCARDIAL PERFUSION SCAN

Noninvasive Scan Early Diagnosis of Cardiac Problems Related to Blood Circulation

Preoperative Assemment of Perfusion / Functional Stauts of Heart

Myocardial Perfusion ScanNormal Scan

Infero-Lateral wall Ischaemia

BRAIN SCAN

● Accurate Localisation of Foci in Refractory Epilepsy Patients

● Neurodegenerative Disorders● Evaluation of Movement Disorders● Cerebrovascular Disorders.

ICTAL SPECT Seizure focus origin in right temporal lobe Highly sensitive

Cerebrovascular Disease

NON INVASIVE

GIVES PERFUSION AT SUB SEGMENTAL LEVEL

EASY FOLLOW UP

Lung Scan Pulmonary Embolism