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5/15/2019 Traci Fox 2019 1 Integrating Duplex Doppler Traci B. Fox, EdD, RT(R), RDMS, RVT Department of Medical Imaging & Radiation Sciences Jefferson College of Health Professions Tel. 215-503-1325 [email protected] Disclosures Royalties from McGraw-Hill and Wolters Kluwer Special Thanks to Gail Size (Inside Ultrasound) for her images In lieu of an 8 am Doppler talk, I’d like to spend the next hour discussing… Game of Thrones Series Finale Spoiler Alert

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Page 1: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

5/15/2019

Traci Fox 2019 1

Integrating Duplex Doppler

Traci B. Fox, EdD, RT(R), RDMS, RVTDepartment of Medical Imaging & Radiation Sciences Jefferson College of Health Professions

Tel. 215-503-1325

[email protected]

Disclosures

• Royalties from McGraw-Hill and Wolters Kluwer

• Special Thanks to Gail Size (Inside Ultrasound) for her images

• In lieu of an 8 am Doppler talk, I’d like to spend the next hour discussing…

Game of Thrones

Series Finale

Spoiler Alert

Page 2: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 2

Biggest Lie You Learn in Clinical

• You’ll never use the physics after you graduate:

Basics of Spectral Doppler

• What is “duplex?”

http://www.ob-ultrasound.net/baker.html

+ +

Basics of Spectral Doppler

Duplex Triplex

Doppler Terminology

• Duplex imaging

• Acquires to 2D imageand Dopplerseparately, notsimultaneously

Doppler Terminology

• Duplex imaging

Frozen duplex Live duplex

Doppler Angle

• The Doppler angle is the angle between the flow and the beam

flow

Page 3: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 3

Doppler Facts…How Many Do You Know?

• The smaller the Doppler angle, the more accurate the velocities

• We don’t use the angle itself, but the cosine of the angle

• 0° is the most accurate angle

• Never use an angle > 60°

• At angles > 60° the degree of error is too high to be reliable

• Highest shift at 0°

Doppler Facts…How Many Do You Know?

• The ___________ (lower/higher) the Doppler angle, the more accurate the velocities

• ________ is the most accurate angle

• Never use an angle > __________

• Highest Doppler shift is at ___ °

• The Doppler shift at 90 °is _____

lower

0°60°

0

0

PW Spectral Doppler and Aliasing

• How do you fix aliasing? Name FOUR ways

Increase the scale/PRF

Increase the Doppler angle

Decrease the transducer frequency

Use continuous wave

PW Spectral Doppler and Aliasing

• Why does aliasing occur?

• Frequency shift > Nyquist limit

• You’re not sampling often enough

Nyquist limit = ½ PRF

Speed Limit

70 mph

Aliasing – Another Example

• Temporal aliasing occurs in other areas of life, such as when a wheel or propeller appear to either not spin or spin backwards

Aliasing – The PW Enemy

• What happens if you don’t sample often enough?

Sample every 15 sec

Sample every 45 sec

Page 4: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 4

Time-Velocity Spectrum(Spectral Analysis)

Time

Ve

loc

ity/F

re

qu

en

cy S

hif

t

Spectral Analysis

• Graph of frequency shift (velocity) over time

Time (5-10ms intervals)

Ve

loc

ity/F

re

qu

en

cy S

hif

t

5cm/s

15cm/s

25cm/s

35cm/s

45cm/s

-5cm/s

-15cm/s

“Peak” Systolic Velocity

https://www.nature.com/articles/s41598-017-16933-x

“Peak” Systolic Velocity

https://www.nature.com/articles/s41598-017-16933-x

Shift 0°= 1.0Velocity 100 cm/s

Shift 60°= 0.5Velocity 50 cm/s

Flow moving at 100 cm/s

Shift 90°= 0Velocity 0 cm/s

“Peak” Systolic Velocity

Flow moving at 100 cm/sIs this really the highest velocity? Or were these red blood cells just traveling at a lower angle?

“Peak” Systolic Velocity

Flow moving at 100 cm/sIs this really the highest velocity? Or were these red blood cells just traveling at a lower angle?

Page 5: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 5

Vector Flow Frequency Shift vs. Velocity

• Why do we have to be 60 degrees or less?

• Degree of error larger at higher angles

• 60 degree angle: A 5˚error in angle, velocity is 15% off

• 70 degree angle: A 5˚error in angle, velocity is 24% off

The Myth of the 60°Angle

Why do we say to use a 60°angle for carotid ultrasound?

• Because that’s what the charts are based on

• Do not force a 60° angle

• 30 – 60 ° angle ok for ICA

The Myth of the 60° Angle

What angle should you use for carotid ultrasound?

• One that is

parallel to the

wall

• One that is

about 30 - 60°

• One that is

consistent with

prior exams

The Myth of the 60° Angle

What angle should you use for carotid ultrasound?

• Why not use

parallel to flow

jet?

• We are imaging

a 3D world in

2 dimensions

• Low

interoperatorreproducability

What Have We Covered So Far?

• We’re not measuring velocity, but viewing the Doppler frequency shift converted to velocity

• Angle correction needed to display “correct” velocity

• Higher angles result in higher errors

• No, you shouldn’t use 60 degree angle when vessel does this:

Page 6: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 6

How Well Do You Know Your Waveforms?

• What are the three types of flow?

Plug Laminar Turbulent

How Well Do You Know Your Waveforms?

• So…laminar flow is what normal blood flow looks like, right?

How Well Do You Know Your Waveforms?

• So…laminar flow is what normal blood flow looks like, right?

How a Stenosis Affects Flow

Pre-stenosis

Poststenotic turbulenceAt stenosis/jet

How Well Do You Know Your Waveforms?

• Spectral broadening…why?

• Pathology, turbulence (nl vs. abnl), tortuosity, spectral gain ↑, CW)

Spectral Analysis

Keep the cursor in thecenter of the vessel(fastest flow) for clear

window

or

Cursor towards the edge (boundary layer) or gate to wide open results in broadening (no window)

Page 7: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 7

“Pretty” vs. “Search & Destroy”

• Normal vessel

• Go with pretty, laminar flow pattern

• Small gate, optimized gain

• Any suspected pathology, including stenosis, near-occlusion

• Search and destroy mode (i.e., max sensitivity)

Appropriate Scale for Low/No Flow

• High sensitivity setting…searching for flow

• Low scale

• Increase gain (but not too much)

• Lowest wall filter

• Open gate wide

Max Sensitivity Push this

Gate Size

• Gate placed in vessel full of plaque• Plaque can be anechoic (i.e., invisible)

• Gate is too narrow… does not detect flow

Gate Size

• Gate placed in vessel full of plaque

• Open gate to “search” for flow

• Effectively turns PW gate in sort-of a CW probe (i.e., large sample volume)

• With large gate you’ll find the flow

Where to Measure in Blood Vessel With Stenosis

The “Three Musketeers”

Before stenosis • At stenosis • After stenosis

Walk the cursor through. Open gate to capture ALL velocities

Phasicity

Time

Am

plitu

de

Phasicity relates to the bed being fed by the vessel and not to the

vessel itself

Page 8: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Phasicity

• Phasicity relates to the bed being fed by the

vessel and not to the vessel itself

• i.e., the DISTAL bed

Downstream arteriole

Downstream arteriole

© Traci Fox 2019

Spectral Doppler and Phasicity

• Is this waveform normal?

In a resting leg?

What is the distal bed doing?

In an ICA?

• Is this waveform normal?

No

Phasicity

• Monophasic flow always abnormal in (resting) lower extremity arteries

• Persistently dilated downstream vessels due to disease

What the heck is this?

• Vertebral a.

https://pubs.rsna.org/doi/pdf/10.1148/rg.256045013

• Occult steal• Reversed late systolic flow

after exercise

How to Start a Riot at an Ultrasound Conference…

• What type of waveform is this?

Monophasic? Biphasic? Low resistance? High resistance?

How to Start a Riot at an Ultrasound Conference…

• What about this? Monophasic means low-resistance, right?

Does this look like a low-resistance bed? What defines “low”?https://journals.sagepub.com/doi/full/10.1177/8756479311435524

Page 9: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 9

Scissons & Neumyer: JDMS 31(5), 2015Arterial Doppler Waveforms: The Confusion Continues What Does the Research Say?

• Everyone agrees this is monophasic

What Does the Research Say?

• Everyone agrees this is triphasic (multiphasic)

What Does the Research Say?

• So is this high resistance or low resistance?

• Better question: is it normal?

What Does the Research Say?

• Everything else is subject to debate

• Remember origins of “triphasic,” “monophasic” and “biphasic”

• audio patterns with CW Doppler or phonoangiography

• Resistive index (RI)

• (PSV-EDV) / PSV

• Pulsatility index (PI)

• (PSV-EDV) / Mean© Traci Fox 2019

Spectral Doppler of Aorta

Aorta waveform will change depending on location

(supra- or infrarenal)

Page 10: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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What Waveform is This?

Image from Kupinski, A., The Vascular System (Diagnostic Medical Sonography Series), 2d ed. Wolters Kluwer

Post-stenoticturbulence (PST)

What Waveform is This?

RightProximal CCA

http://vascularmedicinelab.com/?cat=19

Severe CHF

Tardus Parvus

• Signifies significant disease proximal to point of sampling

• Tardus parvus

• Delayed upstroke (acceleration) from proximal obstruction

Tardus Parvus

http://ndt.oxfordjournals.org/cgi/content/full/15/4/539

http://www.jultrasoundmed.org/cgi/content/full/23/8/1057

Normal

Abnormal

What Waveform is This?

Turbulence right CCA means brachiocephalic a. or prox CCA stenosis(If left CCA, means prox left CCA stenosis)

Know your anatomy!

What Waveform is This?

RT PROX CCA

Tardus parvus proximal right CCA – indicates more proximal obstructionNEED TO KNOW ANATOMY

Either origin of CCA or brachiocephalic a.

When you see tardus parvus in a vessel, ask yourself, what did I miss?

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Traci Fox 2019 11

Venous Waveforms

• What are the characteristics of normal venous waveforms in the lower extremities?

Respiratory phasicity Non-pulsatile

Not continuous Spontaneous?

Augmentation?

© Traci Fox 2019

Normal and abnormal LE venous waveforms

Venous Waveforms

© Traci Fox 2019

Venous Waveforms

• Upper extremities:

• Blood flow returns to heart on deep inspiration

• Lower extremities

• Blood flow is returns to heart on exhalation

© Traci Fox 2019

Venous Waveforms

• Central upper extremity and central venous waveforms more likely to transmit cardiac pulsations related to right heart

• Lower extremities should not have cardiac-related waveforms

• It is abnormal to have pulsatility in LE veins

© Traci Fox 2019

Venous Waveforms

• Normal hepatic veins during respiration

• Normal distal IVC

Neumyer, M. M. (2012). Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels by Analysis of Doppler Spectral Waveforms. Journal for Vascular Ultrasound,36(2), 113-122.

© Traci Fox 2019

Breathing and Central Venous Waveforms

Valsalva

Quiet respiration

Page 12: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 12

© Traci Fox 2019

Venous Waveforms

Normal Tricuspid Regurgitation

Pellerito, J., & Polak, J. F. (2012). Introduction to Vascular Ultrasonography E-Book: Expert Consult-Online and Print. Elsevier Health Sciences.

© Traci Fox 2019

Venous Waveforms

• Rouleaux flow: DVT precursor or harmless finding?

• Usually inconsequential

• Could be positional, other hemodynamic factors

• CAN be seen in presence of more central obstruction

Pellerito, J., & Polak, J. F. (2012). Introduction to Vascular Ultrasonography E-Book: Expert Consult-Online and Print. Elsevier Health Sciences.

© Traci Fox 2019

Abnormal Venous Waveforms

• Continuous venous waveformfrom increased resistance inin liver

Selis, J. E., & Kadakia, S. (2009). Venous Doppler sonography of the extremities: a window to pathology of the thorax, abdomen, and pelvis. American Journal of Roentgenology, 193(5), 1446-1451.

© Traci Fox 2019

Abnormal Venous Waveforms

• Turbulence from intrinsic thrombus

Selis, J. E., & Kadakia, S. (2009). Venous Doppler sonography of the extremities: a window to pathology of the thorax, abdomen, and pelvis. American Journal of Roentgenology, 193(5), 1446-1451.

Measuring Velocities in Veins

• Do you have validated criteria?

• How will the information change the management of the patient?

• Ergonomics issue

Q1

• At the point of a stenosis, what happens to the velocity?

Image from Kupinski, A., The Vascular System (Diagnostic Medical Sonography Series), 2d ed. Wolters Kluwer

It increases

Page 13: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 13

Q2

• When you see the image below, the disease is most likely

Proximal to the point of sampling

Q3

• You see color in the tissue adjacent to an artery. Does that mean “there’s a bleeder?”

“We got a bleeder!”

Q3

• You see color in the tissue adjacent to an artery. Does that mean “there’s a bleeder?”

Color bruit

Q4

• True or False: this waveform is abnormal.

You don’t know what vessel it is! Okay for ICA, not okay for resting LE

Q5

• This waveform implies…

Q5

• This waveform implies…

Page 14: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Q6

• What happens to the pressure at the point of a stenosis?

Image from Kupinski, A., The Vascular System (Diagnostic Medical Sonography Series), 2d ed. Wolters Kluwer

Q6

• What happens to the pressure at the point of a stenosis?

Image from Kupinski, A., The Vascular System (Diagnostic Medical Sonography Series), 2d ed. Wolters Kluwer

Velocity goes up, pressure goes down#Bernoulli

Q7 What is Causing This Waveform?

Image courtesy of Gail P. Size, BS, RPhS, RVS, RVT, FSVU, President, Inside Ultrasound, Inc.

“Water Hammer” Pulse

• Aortic insufficiency/regurgitation causes sharp upstroke and sharp downstroke

• This waveform has reversal of flow due to severe regurgitation

Image courtesy of Gail P. Size, BS, RPhS, RVS, RVT, FSVU, President, Inside Ultrasound, Inc.

Q8 What is Causing this Waveform?

Image courtesy of Gail P. Size, BS, RPhS, RVS, RVT, FSVU, President, Inside Ultrasound, Inc.

Right-Sided Heart Failure

• CFV with pulsatile flow

• Caused by elevated right-side heart failure

Image courtesy of Gail P. Size, BS, RPhS, RVS, RVT, FSVU, President, Inside Ultrasound, Inc.

Page 15: Disclosures - Scott Memorial Libraryjeffline.jefferson.edu/jurei/conference/pdfs/vascular/May...Characterization of Blood Flow Patterns in the Hepatoportal, Mesenteric, and Renal Vessels

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Traci Fox 2019 15

Q9 What is Causing These Waveforms?

A.

B.

Image from Kupinski, A., The Vascular System (Diagnostic Medical Sonography Series), 2d ed. Wolters Kluwer

A. IABP & B. LVAD

• A. Intraaortic balloon pump (IABP)

• B. Continuous flow left ventricular assist device (LVAD)

• Will not get accuratevelocities – be sure tomention in report

Image from Kupinski, A., The Vascular System (Diagnostic Medical Sonography Series), 2d ed. Wolters Kluwer

Q10 What is Causing This Waveform?

Image courtesy of Gail P. Size, BS, RPhS, RVS, RVT, FSVU, President, Inside Ultrasound, Inc.

Hint:It’s bilateral

Severe Congestive Heart Failure

• Tardus parvus waveform implies proximal disease

• However, bilateral tardus parvus implies cardiac origin

• This patient had aortic stenosis

Image courtesy of Gail P. Size, BS, RPhS, RVS, RVT, FSVU, President, Inside Ultrasound, Inc.

Q11 What is Causing This Waveform?

Hint:It’s the CFV

Selis, J. E., & Kadakia, S. (2009). Venous Doppler sonography of the extremities: a window to pathology of the thorax, abdomen, and pelvis. American Journal of Roentgenology, 193(5), 1446-1451.

Central Venous Obstruction

• Continuous flow that looks pulsatile because of the very low scale setting

• Cause was a large cystic mass

• Other causes: pregnancy, veryfull urinary bladder, intrinsic thrombus, other cause of extrinsiccompression of IVC or CIV/EIV.

Selis, J. E., & Kadakia, S. (2009). Venous Doppler sonography of the extremities: a window to pathology of the thorax, abdomen, and pelvis. American Journal of Roentgenology, 193(5), 1446-1451.

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Traci Fox 2019 16

Q12. What is Causing This Waveform?

Hint: It’s the RIGHT subclavian v.

https://iame.com/online/upExtVen/content.php

It’s Normal!

(Doesn’t matterthat it’s the right side. Venousanatomy isbilateral in the UE

Summary

• Knowledge of hemodynamics, Doppler settings and anatomy are important to understanding waveforms

• Waveforms are important for knowing normal vs. disease

Shameless Self Promotion Slide

Thank you

tracifox.com

Go with the flow!