dmbr - seminars...university of california, school of medicine, la jolla - usa a tale of two...

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VIB - UGent DMBR seminars p. 1 of 46 Department for Molecular Biomedical Research Dir.: Prof. Dr. F. Van Roy DMBR - SEMINARS 1998 – 2011 1. Thursday October 15, 1998 11h30-12h30 Host: R. Contreras (09)264.51.36 Dr. Els VAN DAMME Lab. of Phytopathology & Plant Protection, KULeuven Plant lectins: Versatile proteins with important perspectives in biotechnology and glycoconjugate research. 2. Thursday October 22, 1998 11h30-12h30 Host: G. Haegeman (09)264.51.66 Dr. Erno VREUGDENHILL Leiden/Amsterdam Centre for Drug Research, Dept. Medical Pharmacology, Leiden – Nederland Molecular dissection of glucocorticoid action in the rat hippocampus: Application of differential display & serial analysis of gene expression. 3. Thursday October 29, 1998 11h30-12h30 Host: F. Van Roy (09)264.50.17 Dr. John G. COLLARD The Netherlands Cancer Institution, Division of Cell Biology, Amsterdam - Nederland Rho-like GTPases: their role in cell adhesion and invasion. 4. Thursday November 5, 1998 11h30-12h30 Host: P. Vandenabeele (09)264.87.16 Dr. Tibor VANTUS Semmelweis, Univ. of Medicine, Dept. of Medical Chem., Budapest – Hungary MAPkinase signaling pathways and the induction of apoptosis by the tumor- selective somatostatin-analog TT-232 in A431 cells. 5. Thursday November 12, 1998 11h30-12h30 Host: F. Van Roy (09)264.50.17 Dr. Sergey LITVINOV University of Leiden, Dept. of Pathology, Leiden - Nederland Ep-CAM and mammary gland morphogenesis. 6. Thursday November 19, 1998 11h30-12h30 Host: N. Mertens (09)264.51.34 Dr. Ronny LEEMANS University of Basel, Zoological Institute, Basel – Switzerland Embryonic brain development in Drosophila. 7. Thursday December 3, 1998 11h30-12h30 Host: J. Grooten (09)264.53.10 Dr. Guido VAN HAMME Tropisch Instituut, Afdeling Immunologie, Antwerpen Interaction between dentritic cells, HIV and T cells. 8. Thursday December 10, 1998 11h30-12h30 Host: R. Contreras (09)264.51.36 Dr. Merja PENTILLA VTT, Helsinki - Finland Kinetics of protein secretion in Trichoderma.

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Page 1: DMBR - SEMINARS...University of California, School of Medicine, La Jolla - USA A tale of two kinases: IKK and the control of NF-κB activity. 47. Friday February 11, 2000 11h30-13h00

VIB - UGent DMBR seminars p. 1 of 46

Department for Molecular Biomedical Research Dir.: Prof. Dr. F. Van Roy

DMBR - SEMINARS

1998 – 2011

1. Thursday

October 15, 1998 11h30-12h30 Host: R. Contreras (09)264.51.36

Dr. Els VAN DAMME Lab. of Phytopathology & Plant Protection, KULeuven Plant lectins: Versatile proteins with important perspectives in biotechnology and glycoconjugate research.

2. Thursday October 22, 1998 11h30-12h30 Host: G. Haegeman (09)264.51.66

Dr. Erno VREUGDENHILL Leiden/Amsterdam Centre for Drug Research, Dept. Medical Pharmacology, Leiden – Nederland Molecular dissection of glucocorticoid action in the rat hippocampus: Application of differential display & serial analysis of gene expression.

3. Thursday October 29, 1998 11h30-12h30 Host: F. Van Roy (09)264.50.17

Dr. John G. COLLARD The Netherlands Cancer Institution, Division of Cell Biology, Amsterdam - Nederland Rho-like GTPases: their role in cell adhesion and invasion.

4. Thursday November 5, 1998 11h30-12h30 Host: P. Vandenabeele (09)264.87.16

Dr. Tibor VANTUS Semmelweis, Univ. of Medicine, Dept. of Medical Chem., Budapest – Hungary MAPkinase signaling pathways and the induction of apoptosis by the tumor-selective somatostatin-analog TT-232 in A431 cells.

5. Thursday November 12, 1998 11h30-12h30 Host: F. Van Roy (09)264.50.17

Dr. Sergey LITVINOV University of Leiden, Dept. of Pathology, Leiden - Nederland Ep-CAM and mammary gland morphogenesis.

6. Thursday November 19, 1998 11h30-12h30 Host: N. Mertens (09)264.51.34

Dr. Ronny LEEMANS University of Basel, Zoological Institute, Basel – Switzerland Embryonic brain development in Drosophila.

7. Thursday December 3, 1998 11h30-12h30 Host: J. Grooten (09)264.53.10

Dr. Guido VAN HAMME Tropisch Instituut, Afdeling Immunologie, Antwerpen Interaction between dentritic cells, HIV and T cells.

8. Thursday December 10, 1998 11h30-12h30 Host: R. Contreras (09)264.51.36

Dr. Merja PENTILLA VTT, Helsinki - Finland Kinetics of protein secretion in Trichoderma.

Page 2: DMBR - SEMINARS...University of California, School of Medicine, La Jolla - USA A tale of two kinases: IKK and the control of NF-κB activity. 47. Friday February 11, 2000 11h30-13h00

VIB - UGent DMBR seminars p. 2 of 46

9. Thursday December 17, 1998 11h30-12h30 Host: F. Van Roy (09)264.50.17

Dr. Christoph REDIES Univ. Hospital Essen, Institute of Anatomy, Essen – Germany Cadherin expression in the brain: From segments to synapses.

10. Monday January 11, 1999 16h00-17h00 Host: G. Berx (09)264.53.18

Dr. Parry GUILFORD Cancer Genetics Lab., Dept. of Biochemistry, Otaga – New Zealand Germine E-cadherin mutations in familial gastric cancer.

11. Thursday January 14, 1999 11h30-12h30 Host: P. Brouckaert (09)264.87.11

Dr. Timo L.M. TEN HAGEN Univ. Hospital Rotterdam, Dept. Exp. Surgical Oncology, Rotterdam - Nederland Application of TNF-alpha in the treatment of solid tumours.

12. Thursday January 21, 1999 11h30-12h30 Host: G. Haegeman (09)264.51.66

Dr. Hinrich GRONEMEYER IGBMC, Centre Universitaire de Strasbourg – France Nuclear receptor coregulators in transactivation and transrepression: What are the mechanistic insights from structure-function studies and ligand design?

13. Thursday January 28, 1999 11h30-12h30 Host: C. Libert (09)264.87.10

Dr. Peter CARMELIET Dept. of Transgene Technology & Gene Therapy, VIB - KULeuven Molecular mechanisms of angiogenesis and vascular disorders.

14. Thursday February 4, 1999 11h30-12h30 Host: R. Beyaert (09)264.51.43

Dr. Anne-Mieke VANDAMME Rega Institute & University Hospitals, AIDS Reference Laboratory, KULeuven Gene regulation for the human retroviruses HIV and HTLV, and possible interactions in cases of double infection.

15. Wednesday February 10, 1999 11h30-12h30 Host: P. Vandenabeele (09)264.87.16

Dr. Ivan SHATSKY Belozersky Institute, Moscow State University, Moscow - Russia Molecular mechanisms of eukaryotic translation initiation: an update.

16. Thursday February 11, 1999 11h30-12h30 Host: P. Vandenabeele (09)264.87.16

Dr. Patrizia AGOSTINIS Afdeling Biochemie, Campus Gasthuisberg, KULeuven Cell signaling pathways during photosensitization.

17. Friday March 5, 1999 11h30-12h30 Host: R. Beyaert (09)264.51.43

Dr. Luke O’NEILL Trinity College Dublin, Dept. of Biochemistry, Dublin - Ireland Signalling pathways activated by the interleukin 1 receptor family: common signals activated by IL1, IL18 and LPS.

18. Friday March 12, 1999 11h30-12h30 Host: P. Vandenabeele (09)264.87.16

Dr. Marcel LEIST University of Konstanz, Konstanz - Germany The role of intracellular ATP in apoptotic cell death.

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19. Thursday March 18, 1999 11h30-12h30 Host: C. Libert (09)264.87.10

Dr. Peter HEINRICH Institut für Biochemie, RWTH, Aachen - Germany Il-6 type signalling through the gp130/Jak/STAT pathway.

20. Friday March 26, 1999 11h30-12h30 Host: F. Van Roy (09)264.50.17

Dr. Eugene LUKANIDIN Danish Cancer Society, Div. for Cancer Biology, Copenhagen -Denmark Intra-cellular and extra-cellular function of Metastasin.

21. Friday April 2, 1999 11h30-12h30 Host: R. Beyaert (09)264.51.43

Dr. Johannes A. SCHMID VIRCC, Dept. Vascular Biol. & Thrombosis Research, Vienna Austria Interplay between NF-kappaB and anti-apoptotic pathways.

22. Friday April 16, 1999 11h30-12h30 Host: C. Libert (09)264.87.10

Dr. George KOLLIAS Hellenic Pasteur Institute, Lab. of Molecular Genetics, Athens-Greece Understanding TNF/TNF-R biosynthesis and function in genetically manipulated mice.

23. Friday April 23, 1999 11h30-12h30 Host: E. Remaut (09)264.51.30

Dr. Werner FALK Dept. of Internal Medicine I, University of Regensburg, Regensburg - Germany Signals from the IL-1 receptor: oldies but goodies.

24. Monday April 26, 1999 16h00-17h00 Host: P. Vandenabeele (09)264.87.16

Dr. Kodi S. RAVICHANDRAN Beirne Carter Center for Immunol. Research, Univ. of Virginia - USA Signaling via the adapter protein SHC and the inositol phosphatase ship in lymphocytes. .

25. Friday April 30, 1999 11h30-12h30 Host: C. Haegeman (09)264.51.66

Dr. Claus SCHEIDEREIT Max-Delbrück-Centrum für Molekulare Medizin, Berlin - Germany Dual functions of transcription factor NF-κB in apoptosis protection and cell cycle progression of tumor cells.

26. Friday May 7, 1999 11h30-12h30 Host: R. Beyaert (09)264.51.43

Dr. John KYRIAKIS Massachusetts General Hospital East, Diabetes Research Laboratory, Charlestown - USA Cytokine signaling to SAPK/JNK and p38.

27. Friday May 21, 1999 11h30-12h30 Host: F. Van Roy (09)264.50.17

Dr. Jürgen BEHRENS Max-Delbrück-Centre for Molecular Medicine, Berlin - Germany Control of beta-catenin in development and tumorigenesis.

28. Friday May 28, 1999 11h30-12h30 Host: P. Brouckaert (09)264.87.11

Dr. Curzio RUEGG Centre Pluridisciplinaire d’Oncologie, ISREC, Lausanne - Switzerland Endothelial cell integrins: mediators of tumor angiogenesis and target molecules for anti-angiogenic therapie

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29. Friday June 4, 1999 11h30-12h30 Host: G. Haegeman (09)264.51.66

Dr. Marie-Christine GAILLARD Medical School WIC, Wits University, South Africa The identification of alpha-1-antitrypsin variants in relation to atopic factos in South African patients with chronic inflammatory diseases.

30. Friday June 11, 1999 11h30-12h30 Host: P. Vandenabeele (09)264.87.16

Dr. Margot THOME Institut de Biochimie, ISREC, Epalignes – Switzerland Signalling through death domains, death effector domains and caspase recruitment domains.

31. Friday June 18, 1999 11h30-12h30 Host: P. Vandenabeele (09)264.87.16

Dr. Kris HUYGEN Dept. Mycobacterial Immunology, Pasteur Institute of Brussels DNA vaccines: application to tuberculosis.

32. Thursday June 24, 1999 11h30-12h30 Host: G. Haegeman (09)264.51.66

Dr. Henk STUNNENBERG Dept. of Molecular Biology, Universiteit Nijmegen, The Netherlands A novel TBP-containing complex involved in transcription regulation in embryonal carcinoma cells.

33. Friday June 25, 1999 11h30-12h30 Host: C. Libert (09)264.87.10

Dr. Martin HRABE DE ANGELIS Institute for Mammalian Genetics, Genome Project Group, Neuherberg - Germany Animal models for human diseases: the large scale ENU mouse-mutagenesis screen within the German human Genome Project.

34. Thursday July 1, 1999 11h30-12h30 Host: C. Libert (09)264.87.10

Dr. Jan NAESSENS Int. Livestock Research Institute (ILRI), Nairobi - Kenya Role of aquired and innate immune mechanisms in resistance of cattle to African trypanosomes.

35. Thursday July 8, 1999 11h30-12h30 Host: N. Mertens (09)264.51.34

Dr. Joanne BANYER John Curtis School of Medical Research, Australian National Univ., Experimental Haematology Group, Australia Differential gene expression during dendritic and macrophage maturation from a common myeloid progenitor.

36. Monday August 30, 1999 11h30-12h30 Host: G. Haegeman (09)264.51.66

Dr. J. BRADLEY Addenbrooke’s Hospital, Dept. of Medicine, Cambridge – U.K. Subcellular localization of receptors and adaptor molecules in TNF signalling.

37. Thursday October 14, 1999 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Bart DE STROOPER VIB-K.U.Leuven, Center for Human Genetics, Leuven - Belgium The presenilins control the proteolytic cleavage of the transmembrane domains of APP and Notch.

38. Thursday October 21, 1999 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Natasha KRALLI University of Basel, Biozentrum, Dept. of Biochemistry, Basel - Switzerland Genetic approaches to steroid hormone signaling.

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39. Thursday October 28, 1999 11h30-13h00 Host: R. Contreras / A. De Bruyn (09)264.5136/(09)264.4475

Dr. Johannes VLIEGENTHART University of Utrecht, Bijvoet Center, Dept. of Bio-Organic Chemistry, Utrecht – The Netherlands Multifunctional aspects of glycoproteins.

40. Thursday November 4, 1999 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. Matthias GRELL University of Stuttgart, Institut für Zellbiologie und Immunologie, Stuttgart - Germany Live and let die: Induction of cell death by tumor necrosis factors.

41. Thursday November 18, 1999 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Janusz JANKOWSKI University Hospital, Institute for Cancer Studies, Epithelial Laboratory, Birmingham, U.K. The role of genetic and epigenetic changes in the cadherin/catenin complex in the progression of Barrett’s metaplasia.

42. Thursday November 25, 1999 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Alain ISRAEL Institut Pasteur, Unité de Biologie Moléculaire de l’Expression Génique, Paris - France Control of NFκB activity by IκB molecules.

43. Thursday December 2, 1999 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Louis C. MAHADEVAN University of Oxford, Dept. of Biochemistry, Nuclear Signalling Lab., Oxford – U.K. MAP kinase-mediated signalling to chromatin and gene induction.

44. Thursday December 9, 1999 11h30-13h00 Host: K. Vleminckx (09)264.87.19

Dr. Andreas HECHT Max-Planck-Institut für Immunbiologie, Freiburg - Germany Beta-catenin and its function as transcriptional coactivator in cancer and development.

45. Thursday December 16, 1999 11h30-13h00 Host: R. Contreras (09)264.51.36

Dr. Lode WIJNS VIB-VUB, Dienst ULTR, Dept. Immunologie, Parasitologie & Ultrastructuur, St.-Genesius-Rode - Belgium Protein-Carbohydrate recognition: rules from crystallographic studies.

46. Monday January 31, 2000 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Michael KARIN University of California, School of Medicine, La Jolla - USA A tale of two kinases: IKK and the control of NF-κB activity.

47. Friday February 11, 2000 11h30-13h00 Host: R. Contreras (09)264.51.36

Dr. Paul T. MAGEE University of Minnesota, Dept. of Genetics and Cell Biology, Minnesota - USA Genomic studies of Candida albicans: what the physical map can tell us.

48. Friday February 25, 2000 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. Pierre F. PIGUET Univ. of Geneva, WHO-IRTC, Dept. of Pathology, Geneva - Switserland Platelets in pathophysiology.

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49. Friday March 3, 2000 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Matthias GAESTEL Martin-Luther-Universität, Innovationskolleg Zellspezialisierung, Halle - Germany Signalling by MAPKAP kinase 2: mechanisms and function in vivo.

50. Friday March 10, 2000 11h30-13h00 Host: P. Vandenabeele (09)264.87.16

Dr. Pietro GHEZZI Instituto di Ricerche Farmacologiche Mario Negri, Milan - Italy Cytokines and redox enzymes.

51. Thursday March 16, 2000 16h00-17h30 Host: F. Van Roy (09)264.50.17

Dr. Albert REYNOLDS Dept. of Cell Biology, Vanderbilt University, Nashville - USA The catenin p120: a multi-talented effector of cadherin function.

52. Friday March 17, 2000 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. Zhao-Qi WANG IARC, Unit of Gene-Environment Interactions, Lyon - France PARP and apoptosis.

53. Thursday March 23, 2000 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Martin GOTTLICHER Forschungszentrum Karlsruhe, Institut für Genetik, Karlsruhe - Germany Why are dioxins toxic and why not to eat too many Belgian eggs?

54. Friday March 31, 2000 11h30-13h00 Host: J. Grooten (09)264.53.10

Dr. Martine RAES FUNDP, Dept. Biochimie Cellulaire, Namur - Belgium Antioxidants and IL-1 induced NF-κB activation.

55. Friday April 7, 2000 11h30-13h00 Host: J. Grooten (09)264.53.10

Dr. Bart N. LAMBRECHT Erasmus Universiteit Rotterdam, Dept. Longziekten, Rotterdam – The Netherlands Dentritic cells and the regulation of the mucosal immune response in the lung.

56. Friday April 14, 2000 11h30-13h00 Host: R. Beyaert (09)264.51.43

Dr. Jorge MOSCAT CBMSO, Universidad Autonoma Canto Blanco, Madrid - Spain Signalling cell survival and tumor progression through the atypical PKC pathways.

57. Friday April 28, 2000 11h30-13h00 Host: C. Libert (09)264.87.10

Dr. Lieve MOONS VIB3 - K.U.Leuven, Centrum voor Transgene Technologie & Gentherapie, Leuven - Belgium Urokinase mediated plasmin activates matrix metalloproteinases: insights from transgenic mouse models.

58. Friday May 5, 2000 11h30-13h00 Host: P. Vandenabeele (09)264.87.16

Dr. Guy CORNELIS Microbial Pathogenesis Unit, K.U.Leuven & C. de Duve Institute of Cellular Pathology, Brussel - Belgium Interaction between Yersinia and eukaryotic cells.

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59. Friday May 12, 2000 11h30-13h00 Host: E. Remaut (09)264.51.30

Dr. Jeremy WELLS Institute of Food Research, Dept. Microbial Genetics & Physiology Section, Norwich – U.K. Functional genomics of bacterial pathogens.

60. Friday May 19, 2000 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Mechthild HATZFELD Molecular Biology Group of the Medical Faculty, Martin-Luther-Universität, Halle - Germany The role of plakophilin-1 in cell-cell adhesion and cell motility.

61. Friday May 26, 2000 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Pierre D. McCREA Dept. of Biochemistry & Molecular Biology, University of Texas, M.D. Anderson Cancer Center, Houston - USA Evaluation of catenin function in Xenopus embryos and mammalian kidney cells.

62. Tuesday October 10, 2000 10h00-11h30 Host: F. Van Roy (09)264.50.17

Dr. Barry M. GUMBINER Memorial Sloan-Kettering Cancer Center, Cellular Biochemistry and Biophysics Program, New York – U.S.A. Cadherins and catenins in development and cancer.

63. Thursday October 12, 2000 11h30-13h00 Host: C. Libert (09)264.87.10

Dr. François TRONCHE Institut Pasteur, Unité des Virus Oncogènes, Paris - France Genetic dissection of the glucocorticoid function by conditional mutagenesis in mice.

64. Thursday October 19, 2000 11h30-13h00 Host: E. Remaut (09)264.51.30

Dr. Deborah O’NEIL VIB-1 - Univ. of Ghent, Dept. of Molecular Biology, Ghent - Belgium Regulation of beta-defensin expression: endogenous peptide antibiotics of the gastrointestinal tract.

65. Thursday November 9, 2000 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Stuart N. FARROW Glaxo Wellcome, U.K. Death receptors, NF-kB and apoptosis; strategies for therapeutic intervention.

66. Thursday November 16, 2000 11h30-13h00 Host: R. Beyaert (09)264.51.43

Dr. Kim BURNS Université de Lausanne, Institut de Biochimie, Epalinges - Switzerland Interleukin-1 signal transduction.

67. Thursday November 23, 2000 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. Daniela N. MAENNEL University of Regensburg, Dept. of Pathology, Regensburg – Germany Functional characterization of an intracellularily expressed TNF receptor.

68. Thursday November 30, 2000 11h30-13h00 Host: R. Beyaert (09)264.51.43

Dr. Jorge MOSCAT CBMSO, Universidad Autonoma Canto Blanco, Madrid - Spain Signalling cell survival and tumor progression through the atypical PKC pathways.

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69. Thursday December 7, 2000 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Amparo CANO Instituto de Investigaciones Biomedicas CSIC-UAM, Madrid - Spain Understanding the molecular mechanisms leading to E-cadherin downregulation during tumor progression. Snail transcription factor as a key repressor.

70. Thursday December 14, 2000 11h30-13h00 Host: J. Grooten (09)264.53.10

Dr. Paolo BERNARDI University of Padova, Dept. of Biomedical Sciences, Padova - Italy Mitochondria and cell death: the (w)hole story.

71. Friday February 16, 2001 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Peter TEN DIJKE Nederlands Kanker Instituut, Antoni van Leeuwenhoekziekenhuis, Dept. Cellulaire Biochemie, Amsterdam - Nederland TGF−β receptor signal transduction.

72. Friday February 23, 2001 11h30-13h00 Host: K. Vleminckx (09)264.87.19

Dr. Pierre VANDERHAEGHEN U.L.B., Institute of Interdisciplinary Research, Brussels - Belgium Ephrins and the generation of neuronal connectivity in the mammalian brain.

73. Friday March 2, 2001 11h30-13h00 Host: R. Contreras (09)264.51.36

Dr. Gert MATTHIJS University of Leuven, Center for Human Genetics, Dept. for Molecular Diagnosis, Leuven - Belgium Understanding and diagnosis of congenital disorder of glycosylation.

74. Friday March 16, 2001 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Asifa AKHTAR Adolf-Butenandt-Institut für Molekularbiologie, München - Germany Targeting of histone acetyltransferase MOF to the X chromosome via RNA/chromodomain interactions.

75. Friday March 30, 2001 11h30-13h00 Host: L. Steidler (09)264.87.01

Dr. Elisabeth FURIE University of Dundee, MRC Microbiology & Gut Biology Group, Dept. of Molecular & Cellular Biology, Dundee – U.K. Identification of human rectal flora and their interactions with the host.

76. Friday April 6, 2001 11h30-13h00 Host: L. Steidler (09)264.87.01

Dr. Murray SELKIRK Imperial College of Science, Technology and Medicine, Dept. of Biochemical Parasitology, London – U.K. Resistance and modulation of immunity by parasitic nematodes.

77. Tuesday April 17, 2001 14h00-15h30 Host: G. Haegeman (09)264.51.66

Dr. Joël BOCKAERT UPR-CNRS, Montpellier, France. Role of Homer in localization and signalling of metabotropic glutamate receptors.

78. Friday April 20, 2001 11h30-13h00 Host: X. Saelens (09)264.87.16

Dr. Mike CLEMENS St. Georges Hospital Medical School, Dept. of Biochemistry and Immunology, London – U.K. Regulation of protein synthesis in mammalian cells during the early stages of apoptosis.

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79. Friday April 27, 2001 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Finn Olav LEVY University of Oslo, MSD Cardiovascular Research Center, Dept. of Pharmacology, Oslo - Norway Pharmacological properties and signalling mechanisms of 5-HT4 and 5-HT7 serotonin receptor splice variants.

80. Friday May 4, 2001 11h30-13h00 Host: C. Libert (09)264.87.10

Dr. Frank BERGER University of South Carolina, Coker Life Sciences Building, Dept. of Biological Sciences, Columbia - USA Cancer and the host inflammatory response: does the latter benefit the former?

81. Friday May 11, 2001 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. Georg BREIER Max Planck Institute for Physiological & Clinical Research, Bad Nauheim - Germany Regulation of VEGF receptor expression during vascular development and tumor angiogenesis.

82. Friday May 18, 2001 11h30-13h00 Host: L. Steidler (09)264.87.01

Dr. Jan KOK University of Groningen, Dept. of Molecular Genetics, Haren – The Netherlands Stress in Lactococcus lactis.

83. Friday June 1, 2001 11h30-13h00 Host: P. Rottiers (09)264.87.59

Dr. Patrick GLENISSON Signals, Identification, System Theory and Automation, ESAT, Katholieke Universiteit Leuven Standardizing, Structuring, and Validating Expression Information: From Database to Knowledgebase

84. Friday October 5, 2001 11h30-13h00 Host: P. Vandenabeele (09)264.87.64

Dr. Patrice X. PETIT INSERM/CNRS, Institut Cochin of Molecular Genetics, Team “Apoptose et Mitochondries”, Paris - France On the evolutionary conservation of the cell death machinery: involvement of an apoptosis inducing factor homologue in dictyostelium discoideum cell death.

85. Thursday October 11, 2001 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Bas VAN STEENSEL University of Amsterdam, Swammerdam Institute for Life Sciences, Amsterdam - Nederland Chromatin profiling: large-scale mapping of in vivo target sequences of chromatin proteins.

86. Thursday October 18, 2001 11h30-13h00 Host: E. Remaut (09)264.51.30

Dr. Filip DE KEYSER UZ Gent, Afdeling Rheumatologie, Dept. Inwendige Ziekten, Gent - Belgium New molecular targets for immunotherapy in arthritis.

87. Thursday October 25, 2001 11h30-13h00 Host: K. Vleminckx (09)264.87.19

Dr. François FAGOTTO Max-Planck Institute for Developmental Biology, Div. For Cell Biology, Tuebingen - Germany Beta-catenin signaling: regulatory mechanisms and nuclear localization..

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88. Thursday November 8, 2001 11h30-13h00 Host: J. Grooten (09)264.53.10

Dr. Günter RAPPL University of Cologne, Labo for Tumorgenetics & Cell Biology, Dept. of Internal Medicine, Köln - Germany The CD7- subset of CD4+ memory T-cells is prone to accelerated apoptosis that is prevented by interleukin-15.

89. Thursday November 22, 2001 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Johan SWINNEN K.U.Leuven, Lab. Exp. Medicine and Endocrinology, Dept. of Medicine & Developmental Biology, Leuven - Belgium Increased lipogenesis in cancer cells: mechanisms and clinical implications.

90. Thursday November 29, 2001 11h30-13h00 Host: R. Beyaert (09)264.51.43

Dr. Paul EVANS The Babraham Institute, Molecular Immunology Programme, Cambridge - U.K. The role of A20 and related genes in the regulation of NFκB.

91. Thursday December 6, 2001 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. Pierre COULIE UCL – GECE Unit, Brussels – Belgium Vaccination against cancer: decipherment of rare successes.

92. Thursday December 13, 2001 11h30-13h00 Host: R. Beyaert (09)264.51.43

Dr. Matthias W. HENTZE EMBL, Gene Expression Programme, Heidelberg - Germany Regulation of mRNA fate in the cytoplasm.

93. Thursday December 13, 2001 14h00-15h30 Host: C. Libert (09)264.87.10

Dr. Gerald DE HAAN Dept. of Stem Cell Biology, University of Groningen, the Netherlands Genetic and genomic analysis of mouse hematopoietic stem cells.

94. Friday December 14, 2001 11h30-13h00 Host: G. Berx (09)264.53.18

Dr. Chris TSELEPIS Institute for Cancer Studies & Dept. of Medicine, University of Birmingham, U.K. A modulation of adhesion in cancer.

95. Monday January 14, 2002 11h30-13h00 Host: R. Beyaert (09)264.51.43

Dr. Raymond KAEMPFER Dr. Ph. Marcus Professor of Molecular Biology and Cancer Research, Faculty of Medicine, The Hebrew University of Jerusalem, Israel A new role for the RNA-activated protein kinase PKR in TNF mRNA splicing.

96. Wednesday February 20, 2002 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Martin HUELSMEYER University of Berlin, Dept. for Crystallography, Berlin - Germany CD30, the largest TNFR family member associated with Hodgkin disease (expression & purification aspects).

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97. Friday March 1, 2002 11h30-13h00 Host: K. Vleminckx (09)264.87.19

Dr. Wim ANNAERT VIB4 - University of Leuven, Center for Human Genetics, Laboratory for Neuronal Cell Biology, Leuven - Belgium Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins.

98. Friday March 15, 2002 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Gioacchino NATOLI Institute for Research in Biomedicine, Bellinzona - Switzerland The impact of Chromatin dynamics on NF-kB-dependent transcription.

99. Friday March 29, 2002 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Lionel LARUE Institut Curie, CNRS/IC, Orsay – France Role of the cadherin/catenin/IGF1R complex in the transition from an epithelium to a mesenchyme.

100. Friday April 19, 2002 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Gerald THIEL University of Saarland Medical Center, Dept. of Medical Biochemistry and Molecular Biology, Homburg - Germany Regulation of neuronal gene transcription by RE-1 silencing factor (REST).

101. Friday April 26, 2002 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. A. Francis STEWART Technical University of Dresden, Dept. Genomics, Dresden - Germany Fluent DNA engineering using phage homologous recombination mechanisms.

102. Friday May 3, 2002 11h30-13h00 Host: N. Mertens (09)264.51.34

Dr. Arya BIRAGYN National Cancer Institute, Frederick - USA Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity.

103. Friday May 17, 2002 11h30-13h00 Host: C. Libert/F. Van Roy (09)264.87.10/~50.17

Dr. Agnès NOEL ULG, Laboratoire de Biologie des Tumeurs et du Développement, Liège - Belgium The role of Matrix Metalloproteinases in angiogenesis.

104. Friday May 24, 2002 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. David R. GARROD University of Manchester, School of Biological Sciences, Manchester -UK The function and regulation of desmosomal adhesion in epithelial morphogenesis.

105. Friday May 31, 2002 11h30-13h00 Host: R. Contreras (09)264.51.36

Dr. Philip REEVES Massachusetts Institute of Technology (MIT), Dept. of Biology, Cambridge - USA Tetracycline-inducible stable mammalian cell line expression systems for high-level expression of toxic rhodopsin mutants, non-glycosylated rhodopsin, and rhodopsin containing defined N-glycans.

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106. Friday June 14, 2002 11h30-13h00 Host: P. Vandenabeele (09)264.87.

Dr. Jan Paul MEDEMA Dept. of Immunohematology and Bloodtransfusion, Leiden University Medical Center, Leiden, The Netherlands Immune escape artists.

107. Friday June 28, 2002 11h30-13h00 Host: F. Van Roy (09)264.50.17

Drs. Murielle GLONDU Molecular and Cellular Endocrinology of Cancers INSERM U540, Montpellier, France Mitogenic activity of cathepsin in breast cancer

108. Monday July 1, 2002 11h30-13h00 Host: W. Declercq (09)264.51.44

Dr. Geertrui DENECKER Division of Molecular Microbiology, Biozentrum, University of Basel, Switserland Molecular mechanism of Yersinia enterocolitica-induced cell death: to Yop or not to Yop ?

109. Thursday October 3, 2002 11h30-13h00 Host: C. Libert (09) 264.87.10

Dr. Carole WILSON

Division of Allergy and Pulmonary Medicine, Washington University School of Medicine, St. Louis, USA Proteolytic processing of antimicrobial peptides by the metalloproteinase matrilysin (MMP-7)

110. Thursday October 10, 2002 11h30-13h00 Host: G. Haegeman (09) 264.51.66

Dr. Anna BIGAS

Molecular Oncology, Institut de Recerca Oncologica, Barcelona, Spain IκBα and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFκB pathways

111. Thursday October 17, 2002 11h30-13h00 Host: K. Vleminckx (09) 264.87.19

Dr. Gerhart RYFFEL

Institut für Zellbiologie, Universitätsklinikum Essen, Germany Cell lineage labelling in Xenopus using Cre and FLP recombinases

112. Thursday October 24, 2002 11h30-13h00 Host: W. Min Jou (09) 264.51.40

Dr. Hilde CHEROUTRE

La Jolla Institute of Allergy & Immunology, San Diego, USA The receptor/ligand pair, CD8αα-TL, mediates survival of mature and immature TCR activated T cells

113. Thursday October 31, 2002 11h30-13h00 Host: F. Van Roy (09) 264.50.17

Dr. Jonathan SLEEMAN

Institut für Toxikologie und Genetik, Forschungszentrum Karlsruhe, Germany Identification of molecular targets for the inhibition of tumor metastasis formation

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114. Thursday November 7, 2002 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Peter PAUWELS

Centre d'Immunologie Pierre Fabre, St-Julien-en-Genvois, France Do we have pharmacological evidence for diverse signalling via G protein-coupled receptors ?

115. Thursday November 14, 2002 11h30-13h00 Host: P. Brouckaert (09)264.87.11

Dr. Bart VANHAESEBROECK

Cell Signalling Laboratory, Ludwig Institute for Cancer Research, London, UK The role of PI3-kinase signalling enzymes in cancer and inflammation

116. Thursday November 21, 2002 11h30-13h00 Host: F. Van Roy 09-264.50.17

Dr. Thierry VANDENDRIESSCHE & Dr. Marinee CHUAH

Dept. of Transgene Technology and Gene Therapy, V.I.B. - K.U.L., Leuven, Belgium State-of-the-art gene transfer technologies: implications for functional genomics and gene therapy

117. Thursday November 28, 2002 11h30-13h00 Host: G. Haegeman (09)264.51.66

Dr. Richard CASWELL

Cardiff School of Biosciences, UK Dysregulation of IL-6 expression by human cytomegalovirus

118. Thursday December 5, 2002 11h30-13h00 Host: F. Van Roy (09)264.50.17

Dr. Hélène FERACCI

Institut Curie, Paris, France

Kinetics of the E-cadherin trans-interaction studied at the unimolecular level

119. Tuesday December 10, 2002 13h00-14h30 !!! Host: C. Libert (09)264.87.10

Dr. Aernout LUTTUN

Dept. of Transgene Technology and Gene Therapy, V.I.B. - K.U.L., Leuven, Belgium Chronic inflammation: The role of proteolysis and angiogenesis revisited. Therapeutic implications

120. Thursday

December 12, 2002 11h30-13h00 Host: R. Beyaert (09)264.51.43

Dr. Leo A.B. JOOSTEN

Rheumatology Research Laboratory, UMC Nijmegen, The Netherlands The role of IL-1/Toll-like receptor superfamily signaling in experimental arthritis

121. Thursday December 19, 2002 11h30-13h00 Host: P. Vandenabeele (09)264.50.17

Dr. Marc KOCKX

Department of Medicine, U.I.A., Antwerp, Belgium Apoptosis versus autophagic cell death in heart failure

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122. Thursday January 9, 2003 11h30-13h00 Host: J. Grooten 09-264.53.10

Dr. Hans DOOMS

Department of Pathology, UCSF, San Francisco, U.S.A.

Regulation of memory T cell development and survival

123. Tuesday January 21, 2003 11h30-13h00

Host: P. Brouckaert 09-264.87.11

Dr. Ken BLOCH

Cardiovascular Research Center, Massachusetts General Hospital, U.S.A.

The role of nitric oxide synthase in ventricular remodeling: insights gained from genetically-modified mice

124. Monday February 3, 2003 11h30-13h00 Host: W. Declercq 09-264.51.44

Dr. Arun DHARMARAJAN

School of Anatomy & Human Biology, University of Western Australia, Perth, Australia

Factors involved in tumor necrosis factor-alpha-induced corpus luteum apoptosis

125. Friday February 21, 2003 14h00-15h00 !!!

Host: R. Beyaert 09-264.51.43

Dr. Jurg TSCHOPP

Institute of Biochemistry, University of Lausanne, Switzerland

The inflammasome: a novel complex implicated in the maturation of pro-inflammatory cytokines

126. Tuesday March 18, 2003 11h00-12h30 Meeting room 10th floor !! Host: P. Vandenabeele 09-264.87.64

Prof. Walther VAN VENROOIJ

Dept. of Biochemistry, Catholic University Nijmegen, The Netherlands

Citrullination and rheumatoid arthritis: two sides of one coin

127. Friday April 4, 2003 11h30-13h00

Host: N. Mertens 09-264.51.34

Dr. Paula HENDERICKX

Dyax SA, Liège, Belgium

Development of an antibody against the tumor associated antigen MUC1 obtained by phage display

128. Friday April 11, 2003 11h30-13h00

Host: F. Van Roy 09-264.50.17

Dr. Jacqueline JOUANNEAU

Institut Curie, Paris, France

Impact of FGF-1, FGF-2 and cell signaling in angiogenesis and tumor progression

129. Friday May 9, 2003 11h30-13h00

Host: R. Contreras 09-264.51.36

Dr. Myron SZEWCZUK

Department of Microbiology and Immunology, Queen's University, Kingston, Ontario, Canada

TrkA receptor activation and neuronal cell differentiation and survival responses induced by Trypanosome trans-sialidase

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130. Friday May 16, 2003 11h30-13h00 Host: G. Haegeman 09-264.51.66

Dr. François FUKS

Laboratory of Molecular Virology, Faculty of Medicine, ULB - Free University of Brussels

DNA methylation and chromatin: an intimate affair

131. Monday 25-08-2003

Dr. NORGA Koenraad

Dept. of Molecular and Human Genetics, Baylor College of Medicine, Howard Hughes Medical Institute, Houston TX, USA

Identifying pleiotropic neurodevelopmental genes through quantitative trait analysis

132. Wednesday 27-08-2003

Dr. VAN OOSTERHOUT Antoon

Department of Pharmacology & Pathophysiology, Universiteit Utrecht, Nederland

Novel immunotherapeutic strategies for allergic asthma

133. Friday 29-08-2003

Dr. REEVES Philip

Department of Biology, Massachusetts Institute of Technology, Cambridge MA, USA

Tetracycline-inducible mammalian cell line expression systems for high-level regulated expression of rhodopsin and rhodopsin mutants

134. Monday 01-09-2003

Dr. HAIGH Jody

Mount Sinai Hospital, Toronto, Canada

The role of VEGF-A in organogenesis and disease progression

135. Wednesday 03-09-2003

Dr. POULIN Gino

Wellcome Trust Institute, Cancer Research UK, Cambridge University, UK

Genome-wide RNAi screens for transcription regulators in C.elegans

136. Friday 05-09-2003

Dr. MONTAGNE Jacques

Friedrich Miescher-Institut, Basel, Switzerland

The TOR/S6 kinase pathway controls drosophila growth

137. Friday 19-09-2003

Dr. TUCKERMANN Jan

Div. Molecular Biology of the Cell, Deutsches Krebsforschungszentrum, Heidelberg, Germany

The tissue specific function of the glucocorticoid receptor in disease and therapy

138. Monday 22-09-2003

Dr. WOLFRAIM Lawrence

NIH-NCI Cell Regulation & Carcinogenesis, Bethesda MD, USA

Roles for Transforming Growth Factor-beta-1 and its downstream signaling intermediates (Smad3, p21Cip1 and p27Kip1) in the regulation of T-lymphocyte homeostasis

139. Tuesday 23-09-2003

Dr. DELHASE Mireille

Lab. Gene Regulation and Signal Transduction, UCSD, La Jolla CA, USA

IKK and NAK, two major players in the TNF signaling pathways

140. Wednesday 24-09-2003

Dr. MÜLLER Jürgen

NIH-NCI Metabolism Branch, Bethesda MD, USA

Part 1: Signaling to NF-kB RelB ; Part 2: Mediation of IL-2/15-induced signaling to proliferation and apoptosis via the FKBPs 38, 12 and 12.6

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141. Friday 26-09-2003

Dr. NEF Serge

Département de Morphologie, Université de Genève, Switzerland

Requirement of the insulin receptor family function in male sexual determination

142. Wednesday October 29, 2003

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Guy SALVESEN

The Burnham Institute, Program of Apoptosis and Cell Death Research, La Jolla, USA

Caspase activation pathways: conservation and variation

143. Wednesday January 7, 2004

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Stijn DE LANGHE

Dept. Hematology/Oncology, Childrens Hospital, Los Angeles, USA

Mesenchymal differentiation during lung organogenesis

144. Friday January 16, 2004

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Jayanta DEBNATH

Department of Cell Biology, Harvard Medical School, Boston, USA

The effect of oncogenes on the hollow architecture of mammary acini

145. Friday January 30, 2004

11h30-13h00

Host: P. Rottiers 09-33.13.660

Dr. Sylvia BLEUMING

Dept. Experimental Internal Medicine, Academic Medical Center, Amsterdam, the Netherlands

Indian Hedgehod is an antagonist of Wnt signaling in colonic epithelial differentiation

146. Friday February 13, 2004

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Jan DE MEY

Microtubules et Morphogenèse, Université Louis Pasteur, Ecole Supérieure de Biotechnologie de Strasbourg, Illkirch, France

The interactions of microtubules with cortical capture sites during spindle positioning in polarized epithelial cells

147. Monday March 1, 2004

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Marie-Emmanuelle LEGRIER

Institut Curie, Paris, France

Hormonal escape of prostate cancer: Mechanisms and experimental therapeutics

148. Thursday April 1, 2004

11h30-13h00

Hosts: F. Van Roy & G. Berx 09-33.13.601 / 740

Dr. Ingrid ZWAENEPOEL

Unité de Génétique des Déficits Sensoriels, Institut Pasteur, Paris, France

Molecular approach of hereditary deafness and of the auditory function

149. Monday April 5, 2004

11h30-13h00

Hosts: F. Van Roy & G. Berx 09-33.13.601 / 740

Dr. Katleen BRAET

Department of Physiology and Pathophysiology , University Hospital, Ghent University, Belgium

Calcium talk at the blood brain barrier

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150. Thursday April 8, 2004

11h30-13h00

Hosts: F. Van Roy & G. Berx 09-33.13.601 / 740

Dr. Zerihun ASSEFA

Division of Biochemistry, Faculty of Medicine, Catholic University of Leuven, Belgium

Stress-induced apoptosis: various pathways

151. Friday April 9, 2004

11h30-13h00 Host: G. Berx 09-33.13.740

Dr. Eugene TULCHINSKY

Department of Cancer Studies and Molecular Medicine, University of Leicester, UK

Reciprocal regulation of Fos proteins and E-cadherin in cellular models of epithelial-mesenchymal transition

152. Friday April 23, 2004

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Gerhard CHRISTOFORI

Institute of Biochemistry, University of Basel, Switzerland

Distinct mechanisms of tumor metastasis

153. Wednesday May 5, 2004 11h30-13h00

Host: F. Van Roy & Geert Berx 09-33.13.601

Dr. Karine HELLEMANS

Gene Expression Unit, Afdeling Biochemie, Katholieke Universiteit Leuven

Expression of PPARs and RAR/RXRs during hepatic stellate cell transdifferentiation - Implications for liver fibrogenesis

154. Friday May 7, 2004

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Martin KRÖNKE

Inst. Medical Microbiology, Immunology and Hygiene, University of Cologne, Köln, Germany

TNF and sphyngomyelinases in signalling and apoptosis

155. Monday May 10, 2004 11h30-13h00

Host: N. Mertens 09-33.13.610

Dr. Arie GEERLOF EMBL, Heidelberg, Germany

Optimizing protein production at the EMBL

156. Tuesday May 11, 2004

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Benoît DESNUES

Unité des Rickettsies UMR CNRS 6020, Faculté de Médecine de la Timone, Marseille, France

Whipple's disease: transcriptional approach of pathophysiology

157. Thursday May 13, 2004

11h30-13h00 Host: K. Vleminckx 09-33.13.720

Dr. Gerard J.M. MARTENS

Department of Molecular Animal Physiology Nijmegen Center for Molecular Life Sciences (NCMLS) Radboud University Nijmegen, the Netherlands

A cell-specific transgenic approach in Xenopus for functional exploration of neuronal proteins

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158. Wednesday May 19, 2004 14h00-15h30 Host: C. Libert 09-33.13.70

Dr. Stefanie ZERETZKE

GSF, Institute of Experimental Genetics, Neuherberg-Munich, Germany

The European Mouse Mutant Archive (EMMA)

159. Monday May 24, 2004

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Keith JOHNSON

Omaha, Nebraska, USA

A role for cadherins in tumorigenesis

160. Friday May 28, 2004

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Walter BIRCHMEIER

Max-Delbrück-Center for Molecular Medicine, Berlin, Germany

Armadillo proteins in cell adhesion and signalling

161. Friday June 4, 2004

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Jean-Paul THIERY

Institut Curie, Paris, France

Molecular mechanisms controling human bladder carcinoma initiation and progression

162. Friday June 11, 2004 11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Decio L. EIZIRIK

Lab. of Experimental Medicine and JDRF Center for Prevention of Beta Cell Destruction in Europe, ULB, Brussels

Inferring cytokine-induced gene networks contributing to pancreatic beta cell death

163. Tuesday June 22, 2004

14h30-16h00

Host: P. Vandenabeele 09-33.13.760

Dr. David UCKER

Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, USA

Phagocytosis of apoptitic cells is more than just "eat me signals"

164. Friday June 25, 2004

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Boris TURK

Department of Biochemistry and Molecular Biology, Jozef Stefan Institute, Univeristy of Ljublijana, Slovenia

Lysosomal proteases and apoptosis

165. Wednesday July 7, 2004

11h30-13h00 Host: R. Beyaert 09-33.13.770

Dr. Wolf-Dietrich HARDT

Institut für Mikrobiologie, Departement Biologie, ETH Zürich, Switzerland

Molecular mechanism of Salmonella typhimurium enterocolitis

166. Friday August 20, 2004

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Olexandr VOYTYUK

Dept. of Experimental Clinical Chemistry, Lund University, Wallenberg Laboratory, University Hospital Malmö, Sweden

Stem cell factor induced signal transduction

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167. Friday September 3, 2004

11h30-13h00

Host: J. Haigh 09-33.13.730

Dr. Dieter HARTMANN

Neuronal Cell Biology and Gene Transfer, VIB Dept. of Human Genetics, KU Leuven

Shedding and being shed: the two faces of ADAM10

168. Monday September 6, 2004

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Carlos A. CASIANO

Department of Biochemistry and Microbiology, Center for Molecular Biology and Gene Therapy, Loma Linda University School of Medicine, Loma Linda CA, USA

Mechanisms of autoantigen cleavage during caspase-independent cell death

169. Friday October 1, 2004

11h30-13h00

Host: JC. Marine 09-33.13.640

Dr. Thomas FLOSS

GSF Institute, Institute of Developmental Genetics and The German Gene Trap Consortium, Neuherberg Munich, Germany

17.000 pre-fabricated knockouts: Functional analysis of the mouse genome by gene trap mutagenesis

170. Friday October 8, 2004

11h30-13h00

Host: J. Haigh 09-33.13.730

Dr. Axel BEHRENS

Mammalian Genetics Lab, the London Research Institute, Lincoln's Inn Fields Laboratories, London, UK

Transcriptional control by JNK MAP kinases in neurons and T cells

171. Friday October 15, 2004

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Jo VAN GINDERACHTER

Dept. of Biotechnology, Inst. of Molecular Biology, VUB, Brussels

Functional and molecular characterization of the macrophage : Activation state in murine parasite infection and cancer models

172. Wednesday October 20, 2004

11h00-12h30

Host: R. Beyaert 09-33.13.770

Dr. Ruslan MEDZHITOV

Howard Hughes Medical Institute, Yale University School of Medicine, New Haven CT, USA

Toll pathway of host defense

173. Friday October 22, 2004

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Alain CHARIOT

Laboratory of Medical Chemistry, CTCM/CBIG, Université de Liège, Sart-Tilman, Belgium

Critical roles of scaffold proteins in TNF-mediated NF-kB activation

174. Friday October 29, 2004

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Robert FEIL

Institut für Pharmakologie und Toxikologie, Technische Universität München, Germany

Conditional mutagenesis reveals new roles of cGMP signalling in cellular plasticity

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175. Friday November 5, 2004

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Chris REUTELINGSPERGER

Department Biochemistry, Cardiovascular Research Institute, Maastricht University

Annexin A5: a molecular imaging agent of apoptotic cells with apoptosis modulating properties?

176. Friday November 5, 2004

14h30-16h00

Host: P. Vandenabeele 09-33.13.760

Dr. Marion McFARLANE

Centre for Mechanisms of Human Toxicology, MRC Toxicology Unit, University of Leicester, UK

Caspase activation impedes proteasome function during apoptosis

177. Friday November 26, 2004

11h30-13h00

Host: P. Rottiers 09-33.13.660

Dr. Martien KAPSENBERG

Dept. Cell Biology and Histology & Dept. Dermatology, Academic Medical Center, University of Amsterdam, The Netherlands

Dendritic cells and functional polarisation of immunity

178. Friday December 3, 2004

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Minou ADIB-CONQUY

UP Cytokines & Inflammation, Institut Pasteur, Paris, France

Reprogramming of monocytes reactivity in sepsis and systemic inflammatory response syndrome

179. Friday December 10, 2004

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Steve LEY

Division of Immune Cell Biology, National Institute for Medical Research, Mill Hill, London, UK

Activation of the ERK MAP kinase pathway in innate immune responses

180. Friday January 14, 2005 11h30-13h00

Host: P. Rottiers 09-33.13.660

Dr. Fiona POWRI

Sir William Dunn School of Pathology, University of Oxford, UK

Control of immune pathology by regulatory T cells

181. Friday January 28, 2005 11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Eric CHASTRE

Faculté de Médecine Xavier Bichat, Paris, France

Implication of the MAGI-1/PTEN signalisome in stabilization of adherens junction and suppression of invasiveness

182. Friday February 4, 2005 11h30-13h00

Host: K. Vleminckx 09-33.13.720

Dr. Otmar HUBER

Institut für Klinsiche Chemie und Pathobiochemie, Charité Campus Benjamin Franklin, Berlin, Germany

Identification of new modulators of LEF-1/TCF/beta-catenin signaling activity

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183. Friday February 18, 2005 11h30-13h00

Host: G. Berx 09-33.13.740

Dr. Jos JONKERS

the Netherlands Cancer Institute NKI, Amsterdam, the Netherlands

Conditional mouse models of breast cancer

184. Friday March 11, 2005 11h30-13h00

Host: X. Saelens 09-33.13.650

Dr. Frank van KUPPEVELD

Department of Medical Microbiology, Center for Molecular Life Sciences Radboud University Nijmegen, The Netherlands

Cell biology of picornavirus infection

185. Friday March 25, 2005 11h30-13h00

Host: J. Grooten 09-33.13.650

Dr. Hans DOOMS

Dept. of Pathology, Medical Sciences, UCSF, San Francisco, California, USA

Regulation of IL-2 and IL-7 receptors in the life of a T cell

186. Friday April 29, 2005 11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Stefan ROSE-JOHN

Christian-Albrechts-Universität zu Kiel, Medical Faculty, Kiel, Germany

The role of Toll-like receptors in immunity: lessons from knockout mice

187. Friday May 13, 2005 11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Lena ALEXOPOULOU

Lab. of TLRs and Innate Immunity, CNRS-INSERM Luminy, Centre d'Immunologie de Marseille-Luminy, France

The role of Toll-like receptors in immunity: lessons from knockout mice

188. Tuesday May 17, 2005 11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Juliet DANIEL

Biology Department, McMaster Unicersity, Hamilton, Canada

The transcriptional repressor Kaiso: roles in signaling and development

189. Friday May 20, 2005 11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Emilio HIRSCH

Department of Genetics, Biology and Biochemistry, University of Torino, Italy

Phosphoinositide 3-kinase: kinase functions and beyond

190. Friday June 3, 2005

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Jannie BORST

Division of Immunology, the Netherlands Cancer Institute (NKI), Amsterdam, the Netherlands

Connections in apoptosis signaling by death receptors and DNA damaging anti-cancer regimens

191. Friday June 10, 2005 11h30-13h00 Host: P. Rottiers 09-33.13.660

Dr. Bart LAMBRECHT

Erasmus University Medical Center, Rotterdam, the Netherlands

Dendritic cells subsets and control of airway mucosal inflammation

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192. Thursday June 16, 2005

11h30-13h00 Host: P. Brouckaert 09-33.13.710

Dr. Ben JANSSEN

Department of Pharmacology and Toxicology, University of Maastricht, the Netherlands

Mechanisms of blood pressure control. Focus on hemodynamic phenotyping in mouse and rat disease models

193. Wednesday June 22, 2005

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Saverio BELLUSCI

Department of Surgery, Developmental Biology Program, Childrens Hospital Los Angeles, Saban Research Institute, Los Angeles, USA

Role of FGF10 in organogenesis andrepair: lessons from studies on lung and gut

194. Friday 24 June, 2005

11h30-13h00 Host: J. Haigh 09-33.13.730

Dr.Genadij RAIVICH

Perinatal Brain Repair Group, Dept. of Obstetrics & Gynaecology, Department of Anatomy, University College London, UK

Molecular mechanisms of CNS inflammation

195. Friday 13 September, 2005

11h30-13h00 Host: C. Libert 09-33.13.700

Dr. Frances BALKWILL

Institute of Cancer at Barts and The London, Queen Mary's School of Medicine and Dentistry, London,UK

Inflammation and cancer, the TNF connection

196. Friday 21 October 2005

11h30-13h00 Host: DMBR & PSB 09-33.13.600

Dr. Katja CONRATH

The VIB Nanobody Service Facility, VIB Department of Cellular and Molecular Interactions, Brussels, Belgium

Nanobody Service Facility: From fortuitous discovery to biotechnological opportunities

197. Friday 28 October, 2005

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Cord BRAKEBUSCH

Junior Group "Regulation of Cytoskeletal Organization", Max Planck Institute of Biochemistry, Martinsried, Germany

The role of Cdc42 in the differentiation of skin stem cells

198. Friday 4 November 2005

11h30-13h00 Host: X. Saelens 09-33.13.620

Dr. Nils LYCKE

Department of Clinical Immunology, Goteborg University, Goteborg, Sweden

Exploiting bacterial enterotoxins for engineering cell targeted vaccine adjuvants

199. Friday 25 November 2005

11h30-13h00 Host: N. Callewaert 09-33.13.620

Dr. Eric RUBIN

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA

Mycobacterial genetics: talkin' TraSH

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200. Friday 25 November 2005

Extra seminar 16h00-17h30 !! Host: P. Vandenabeele 09-33.13.760

Dr. Dusan TURK

Structural Biology Group, Dept. of Biochemistry and Molecular Biology, Jozef Stefan Institute, Ljubljana, Slovenia

Structural biology of cathepsins

201. Friday 2 December 2005

11h30-13h00 Host: R. Beyaert 09-33.13.770

Dr. Sophie JANSSENS

Institute of Biochemistry, University of Lausanne, Epalinges, Switzerland (and DMBR)

DNA damage-induced NF-kB activation

202. Friday 2 December, 2005

14h00-15h00 Host: K. Vleminckx 09-33.13.720

Dr. Muriel PERRON

Université Paris XI, Orsay , France

Hedgehog signaling controls the cell cycle kinetics of stem cells/precursors in Xenopus retina

203. Friday 9 December 2005

11h30-13h00 Host: N. Callewaert 09-33.13.620

Dr. Ari HELENIUS

Institute of Biochemistry, Zurich, Switzerland

The role of N-glycans in protein folding and quality control

204. Friday 16 December, 2005

11h30-13h00

Host: J. Grooten 09-33.13.650

Dr. François HUAUX

Industrial Toxicology and Occupational Medicine Unit, Faculty of Medicine, Universite Catholique de Louvain, Brussels, Belgium

Alternative pathway leading to silica-induced lung fibrosis

205. Wednesday 11 Jan. 2006

11h30-13h00 Host: J. Haigh 09-33.13.730

Dr. Jean-Pierre DAVID

Deutsches Rheuma-Forschungszentrum, Berlin, Germany

The Function of the Ribosomal S6 Kinase RSK2 in bone

206. Friday 13 January 2006

11h30-13h00 Host: P. Brouckaert 09-33.13.710

Dr. Klaus PFEFFER

Institut für Medizinische Mikrobiologie, Heinrich-Heine-Universität, Düsseldorf, Germany

Biology of core TNF cytokines

207. Friday 20 January 2006

11h30-13h00 Host: P. Vandenabeele 09-33.13.760

Dr. Pietro GHEZZI

Mario Negri Institute for Pharmacological Research, Milan, Italy

Erythropoietin in neuroprotection

208. Wednesday 1 Febr. 2006

11h30-13h00 Host: J. Grooten 09-33.13.760

Dr. Regina BRIGELIUS-FLOHE

Department of Biochemistry of Micronutrients, German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany

New insights into vitamin E metabolism and function

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209. Friday 24 February 2006

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Christoph REDIES

Institute of Anatomy, Friedrich Schilller University, Jena, Germany

Cadherins: An adhesive code for brain development

210. Wednesday 1 March 2006

11h30-13h00 Host: N. Callewaert 09-33.13.617

Dr. Filip VAN PETEGEM

Cardiovascular Research Institute, UCSF, San Francisco, USA

Structural insights into inactivation mechanisms of voltage-gated calcium channel

211. Friday 3 March 2006

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Pierre-Antoine DEFOSSEZ

CNRS Institut Curie, Paris, France

Characterization of ZBTB4 and ZBTB38 : two new human transcription factors related to Kaiso

212. Friday 17 March 2006

11h30-13h00 Host: G. Berx 09-33.13.760

Dr. Thomas BRABLETZ

Department of Pathology, University of Erlangen, Germany

Malignant progression in colorectal cancer: EMT, stem cells and beta-catenin

213. Tuesday 21 March 2006

11h30-13h00 Host: J.C. Marine 09-33.13.640

Dr. François FUKS

Hopital Erasme, Université Libre de Bruxelles, Belgium

DNA Methylation: Facts, Clues, Mysteries

214. Friday 28 April 2006

11h30-13h00 Host: R. Contreras 09-33.13.631

Dr. Daniel PEEPER

Division of Molecular Genetics, Netherlands Cancer Institute, Amsterdam, the Netherlands

Exploiting senescence and anoikis: functional cloning of tumor and metastasis genes

215. Joint DMBR-PSB seminar Tuesday 2 May 2006

11h30-13h00

Host: R. Beyaert & M. Holsters

Dr. Herman SPAINK

Department of Cell Biology, Institute of Biology Leiden University, Leiden, the Netherlands

Zebrafish as a model for studying microbial infections

216. Friday 5 May 2006

14h00-15h00 Host: R. Beyaert 09-33.13.770

Dr. Manolis PASPARAKIS

EMBL Mouse Biology Programme, Monterotondo, Italy

The role of IkappaB kinase (IKK) subunits in physiology and disease

217. Friday 19 May 2006

11h30-13h00 Host: K. Vleminckx 09-33.13.720

Dr. Carien NIESSEN

Center for Molecular Medicine (ZMMK), University of Cologne, Germany

Cadherins in epithelial morphogenesis polarity and barrier formation

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218. Wednesday 24 May 2006

11h30-13h00

Host: J. Haigh 09-33.13.730

Dr. Roeland MERKS

Department of Plant Systems Biology, Ghent University and VIB, Ghent, Belgium

Cell-centered computational modeling in developmental biology, and its applications to vasculogenesis and angiogenesis

219. Friday 2 June 2006

11h30-13h00 Host: R. Contreras 09-33.13.631

Dr. Olivier TOUSSAINT

Research Unit on Cellular Biology (URBC), University of Namur (FUNDP), Namur, Belgium

Stress-induced premature senescence : from biomarkers of ageing to molecular mechanisms

220. Friday 9 June 2006

11h30-13h00 Host: N. Mertens 09-33.13.610

Dr. Philippe STAS

Algonomics, Ghent, Belgium

Current challenges in immunogenicity assessment of protein therapeutics

221. Monday 19 June 2006

14h30-16h00 Host: R. Beyaert 09-33.13.770

Dr. Alain CHARIOT

Laboratory of Medical Chemistry/CTCM/CBIG, CHU Sart-Tilman, Université de Liège, Belgium

Linking transcriptional Elongation to a human genetic disease: insight into the Elongator/IKAP-dependent pathways

222. Friday 23 June 2006

11h30-13h00 Host: C. Libert 09-33.13.700

Dr. Jin Mo PARK

Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School,Charlestown MA, USA

Inflammatory signaling network in macrophages

223. Friday 30 June 2006

11h30-13h00 Host: P. Rottiers 09-33.13.660

Dr. Philippe EIGENMANN

Allergologie Pédiatrique, Hôpital des Enfants, Hôpital Universitaire de Genève, Switzerland

Immune modulation in food alllergy

224. Friday 14 July 2006

11h30-13h00 Host: R. Beyaert 09-33.13.770

Dr. Jens STAAL

Department of Plant Biology, Swedish University of Agricultural Sciences, Uppsala Genetic Center, Uppsala, Sweden

Common features in animal and plant innate immunity: conserved or converged?

225. Friday 1 September 2006

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Antoon VAN OOSTERHOUT

Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, the Netherlands

Immunoregulatory mechanisms of allergen immunotherapy in a mouse model of asthma

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226. Friday 8 September 2006

11h30-13h00 Host: C. Chen 09-33.13.635

Dr. Richard A. MILLER

Department of Pathology, Geriatrics Center, University of Michigan School of Medicine, Ann Arbor MI, USA

Size, stress, cancer and aging: Lessons from long-lived mutant mice

227. Wednesday 13 September 2006

14h00-15h30 Host: J. Haigh 09-33.13.730

Dr. Vivek MITTAL

Cancer Genome Research Center, Cold Spring Harbor Laboratory, New York, USA

Bone marrow-derived progenitors are a major determinant of angiogenesis-mediated tumor growth and metastasis

228. Friday 22 September 2006

11h30-13h00

Host: J.C. Marine 09-33.13.640

Dr. Adrian BRACKEN

Biotech Research and Innovation Center, Copenhagen, Denmark

Polycombs on target genes in cell fate transitions and cancer

229. Friday 29 September 2006

11h30-13h00 Host: C. Libert 09-33.13.700

Dr. Valeria POLI

Department of Genetics, Biology and Biochemistry, University of Turin, Torino, Italy

The transcription factor Stat3 and its isoforms in inflammation and oncogenesis

230. Friday 6 October 2006

11h30-13h00 Host: X. Saelens 09-33.13.620

Dr. Joseph VERBEEK

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands

FcgRIV, a full-fledged member of the FcgR family?

231. Friday 20 October 2006

11h30-13h00 Host: N. Callewaert 09-33.13.617

Dr. Markus AEBI

Department of Biology, Institute of Microbiology, Swiss Federal Institute of Technology, Zurich, Switzerland

N-linked protein glycosylation, not only for eukaryotes

232. Friday 27 October 2006

11h30-13h00 Host: C. Libert 09-33.13.700

Dr. Andreas LENGELING

Research Group Infection Genetics, Division of Microbiology, German Research Centre for Biotechnology, Braunschweig, Germany

Genetics of host-pathogen interactions in mice

233. Friday 15 December 2006

11h30-13h00 Host: P. Brouckaert 09-33.13.710

Dr. Olivier FERON

Unit of Pharmacology and Therapeutics University of Louvain Medical School, Brussels, Belgium

Caveolin plays critical roles in post-ischemic VEGF-induced angiogenesis and SDF-1-driven vasculogenesis

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234. Monday 18 December 2006

10h00-11h00

Host: P. Vandenabeele 09-33.13.710

Dr. Thirumala-Devi KANNEGANTI

University of Michigan Medical School, Department of Pathology and Comprehensive Cancer Center, Ann Arbor, Michigan, USA

Critical role for cryopyrin in activation of caspase-1 in response to microbial RNA

235. Thursday 21 December 2006

11h30-13h00 Host: F. Van Roy 09-33.13.601

Dr. Stijn DE LANGHE

Developmental Biology Program, Childrens Hospital Los Angeles, Saban Research Institute, Los Angeles, USA

FGF and Wnt signaling at the interface of mesenchymal progenitor cell differentiation during lung development

236. Friday 19 January 2007

11h30-13h00 Host: X. Saelens 09-33.13.620

Dr. Guus RIMMELZWAAN

Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands

Influenza: Epidemics and Pandemics

237. Friday 9 March 2007

11h30-13h00 Host: J. Haigh 09-33.13.730

Dr. Kurt BALLMER-HOFER

Molecular Cell Biology Group, Paul Scherrer Institut, ETH Zurich, Villigen, Switzerland

Functional and structural analysis of VEGF receptor signaling: how coreceptors make a differencer

238. Monday 12 March 2007

11h30-13h00 Host: P.Vandenabeele 09-33.13.760

Dr. Mohamed LAMKANFI

University of Michigan Medical School, Department of Pathology and Comprehensive Cancer Center, Ann Arbor, Michigan, USA

Role of NLR proteins in Legionella infection

239. Friday 16 March 2007

11h30-13h00 Host: X. Saelens 09-33.13.620

Dr. Hans-Dieter KLENK

Institut für Virologie, Marburg, Germany

Influenza viruses between animals and man : Determinants of host range and pathogenicity

240. Thursday 29 March 2007

11h30-13h00

Host: G. Berx 09-33.13.740

Dr. William S.MARSHAL

Dharmacon Inc., Lafayette CO, USA

Optimization of siRNA: understanding mechanisms and developing standards

241. Friday 30 March 2007

11h30-13h00

Host: G. Berx 09-33.13.740

Dr. Cédric BLANPAIN

Interdisciplinary Research Institute (IRIBHM), Université Libre de Bruxelles, Belgium

Multipotency, activation and early lineage commitment of epidermal stem cells

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242. Friday 6 April 2007

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Hans van NOORT

Division of Biomedical Research, TNO Quality of Life, Leiden, The Netherlands

A novel endogenous protein agonist for Toll-like receptor 3: A signal for repair?

243. Friday 13 April 2007

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Sandra GARDAM

Garvan Institute of Medical Research, Darlinghurst (NSW), Australia

TRAF-mediated regulation of gene expression and survival in B lymphocytes

244. Friday 20 April 2007

11h30-13h00

Host: J.C. Marine 09-33.13.640

Dr. Masashi NARITA

Cancer Research UK, Cambridge Research Institute, Cambridge, UK

Cellular senescence and chromatin architecture

245. Friday 4 May 2007

11h30-13h00

Host: K. Vleminckx 09-33.13.720

Dr. Herbert STEINBEISSER

Institute of Human Genetics, University Heidelberg, Germany

Regulation of morphogenesis by protocadherins: lessons from Xenopus embryos

246. Friday 11 May 2007

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Rik DERYNCK

Program in Cranofacial and Mesenchymal Biology, Department of Cell and Tissue Biology, Institute for Regenerative Medicine, UCSF San Fancisco, USA

Non-Smad signaling pathways complement Smad-mediated signaling by TGF-ß

247. Friday 25 May 2007

11h30-13h00

Host: N. Callewaert 09-33.13.630

Dr. Anant MENON

Department of Biochemistry, Weill Medical College of Cornell University, New York, USA

Protein glycosylation in the endoplasmic reticulum: a lipid perspective

248. Monday 4 June 2007

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Ramiro MASSOL

Department of Cell Biology, Harvard Medical School and CBR Institute for Biomedical Research Inc., Boston MA, USA

Uncoating of Clathrin-coated vesicles

249. Friday 8 June 2007

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Guy CORNELIS

Biozentrum der Universitat Basel, Switzerland

Assembly and operation of the Ysc Yersinia injectisome

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250. Friday 15 June 2007

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Johan DECRUYENAERE

Department of Intensive Care Medicine, Ghent University Hospital, UGent, Belgium

An epidemiological and clinical look on severe sepsis and septic shock

251. Friday 22 June 2007

11h30-13h00

Host: N. Callewaert 09-33.13.630

Dr. Peter SANDERS

Institute for Medical Microbiology, University of Zurich, Switzerland

Lipoprotein synthesis in mycobacteria

252. Friday 29 June 2007

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Boris CHERNYAK

Dept. Bioenergetics, A.N. Belozersky Institute, Moscow State University, Russia

Oxidative stress and mitochondria

253. Friday 6 July 2007

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Fumito ICHINOSE

Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston MA, USA

NO/cGMP signal in myocardial dysfunction

254. Tuesday 21 August 2007

11h30-13h00

Host: J. Haigh 09-33.13.730

Dr. Maxime BOUCHARD

McGill Cancer Centre and Biochemistry Department, McGill University, Montreal, Quebec, Canada

Urogenital system morphogenesis by Gata3 and other key regulatory proteins

255. Friday 24 August 2007

11h30-13h00

Host: J. Van Beeumen 09-264.51.09

with the UGent Department of Biochemistry, Physiology and Microbiology

Dr. Wim HOL

dr. honoris causa of UGent; Director of the Biomolecular Structure Center, University of Washington, Seattle, U.S.A.

Structural Biology in the fight against tropical diseases

256. Friday 7 September 2007

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Corentin SPRIET

Biophotonique Cellulaire Fonctionnelle, Institut de Recherche Interdisciplinaire, Lille, France

Towards the quantification of molecular interactions in living cells

257. Friday 14 September 2007

15h00-16h30

Host: H. Favoreel 09-264.73.74

with the UGent Department of Virology, Parasitology and Immunology and the VIB Department of Medical Protein Research at UGent

Dr. Jonathan CHERNOFF

Fox Chase Cancer Center, Philadelphia, U.S.A.

Inhibitors of p21-activated kinases: thinking outside the (catalytic) box

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258. Friday 28 September 2007

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Luis Miguel MARTINS

MRC Toxicology Unit, University of Leicester, UK

The mitochondrial serine protease HtrA2 and Parkinson's disease

259. Friday 5 October 2007 11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Bart LOEYS

Department of Pediatrics and Medical Genetics, University Hospital, Ghent

New pathologic insights leading to therapeutic strategies for Marfan syndrome and related aneurysm disorders

260. Friday 9 November 2007

11h30-13h00

Host: J. Haigh 09-33.13.640

Dr. Marcus FRUTTIGER

UCL Institute of Ophthalmology, University College London, UK

Development of the retinal vasculature

261. Friday 23 November 2007

11h30-13h00

Host: F. Van Roy 09-33.13.720

Dr. Dimitri SCHOLZ

Division of Cardiology, Medical University of South Carolina, Charleston, USA

Microscopy is the solution

262. Friday 23 November 2007

11h30-13h00

Host: K. Vleminckx 09-33.13.720

Dr. Laurent COEN

Laboratoire Evolution des Régulations Endocriniennes, Muséum National D'Histoire Naturelle, Paris, France

Caspase-9 and XR11 regulate apoptosis/proliferation balance in the metamorphosing nervous system of Xenopus

263. Friday 30 November 2007

11h30-13h00

Host: C. Marine 09-33.13.640

Dr. Lionel LARUE

Cellular regulations and oncogenesis, Institut Curie, Université Paris-Sud, Orsay, France

From melanocytes to melanoma

264. Friday 30 November 2007

14h00-15h00 !

Host: R. Beyaert 09-33.13.770

Dr. Lienhard SCHMITZ

Biochemical Institute, Medical Faculty, University of Giessen, Germany

Apical control of the hypoxic response by an inducible autoregulatory loop between SIAH2 and HIPK2

265. Friday 7 December 2007

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Iain STEPHENSON

Infectious Diseases Unit, Leicester Royal Infirmary, Leicester, UK

Clinical development of pandemic vaccines

266. Friday 14 December 2007

11h30-13h00

Host: J. Haigh 09-33.13.640

Dr. Jan TUCKERMANN

Leibniz Institute for Age Research, Fritz Lipmann Institute, Group of Tissue specific Hormone Action, Jena, Germany

Dimerization of the Glucocorticoid Receptor revisited: Dispensible for anti-inflammation?

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267. Tuesday 15 January 2008 11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Christopher J. GUÉRIN

Leicester, England

Microscopy, from morphology to mechanisms

268. Friday 18 January 2008

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Ineke BRAAKMAN

Cellular Protein Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands

Protein folding in the endoplasmic reticulum

269. Friday 8 February 2008

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Huiyu TIAN

Max-Planck-Institute for Developmental Biology, Tübingen, Germany

Reverse genetics analysis of Wnt signaling in Pristionchus pacificus postembryogenesis

270. Friday 8 February 2008

16h00-17h30

Host: P.Vandenabeele 09-33.13.760

Dr. Malgorzata KUBICA

Faculty of Biochemistry, Biophysics, and Biotechnology, Jagiellonian University, Krakow, Poland

Staphylococcus aureus survival in human macrophages

271. Wednesday 13 February 2008

11h00-12h30

Host: P.Vandenabeele 09-33.13.760

Dr. Gabriel NUNEZ

University of Michigan Medical School, Department of Pathology and Comprehensive Cancer Center, Ann Arbor, Michigan, USA

Nod-like receptors in immunity and disease

272. Friday 29 February 2008

11h30-13h00

Host: N.Callewaert 09-33.13.630

Dr. Bennett COHEN

BioIndustry Strategies LLC, Tucson, USA

Bio-Business 101: A graduate student primer

273. Friday 29 February 2008

14h30-15h30

Host: N.Callewaert 09-33.13.630

Dr. Mehmet INAN

University of Nebraska at Lincoln, USA

Protein production in Pichia pastoris

274. Tuesday 18 March 2008

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Eric VAN DYCK

Department of Immunobiolog, Yale University School of Medicine, New Haven CT, USA

Role of RDM1 in DNA repair, chromatin metabolism and the cell response to viral infection

275. Wednesday 26 March 2008

11h30-13h00

Host: E. Meyer 09-264.73.29

Dr. Harald CARLSEN

Department of Nutrition, Faculty of Medicine, University of Oslo, Norway

In vivo imaging of NF-κB activity

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276. Friday 11 April 2008

11h30-13h00

Host: G. van Loo 09-33.13.774

Dr. Marc SCHMIDT-SUPPRIAN

Molecular Immunology & Signal Transduction Group, Max Planck Institute of Biochemistry, Martinsried, Germany

NF-kB signals in B cell development and lymphomagenesis

277. Friday 18 April 2008

11h30-13h00

Host: G. van Loo 09-33.13.774

Dr. Marco PRINZ

Institute of Neuropathology, Universitätsmedizin of the Georg-August-University, Göttingen, Germany

Innate immune mechanisms in the brain during autoimmunity

278. Friday 25 April 2008

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Valentina MARGARIA

Division of Molecular Angiogenesis, Institute for Cancer Research and Treatment, Torino, Italy

A novel Rab5-based signalling pathway participates in centrosome cohesion

279. Wednesday 7 May 2008

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Camille LOCHT

Institut Pasteur, Lille, France

New approaches for nasal vaccination against whooping cough and other respiratory diseases

280. Friday 9 May 2008

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Karen VRIJENS

Department of Biomedical Sciences, University of Antwerp, Belgium

Ozzy, a Jagged1 vestibular mutant, displays symptoms of Alagille syndrome

281. Friday 16 May 2008

11h30-13h00

Host: C. Libert 09-33.13.774

Dr. Xavier MONTAGUTELLI

Institut Pasteur, Paris, France

Interspecific recombinant congenic strains between C57BL/6 and mice of the Mus spretus species: A powerful tool to dissect genetic control of complex traits

282. Wednesday 28 May 2008

11h30-13h00

Host: G. Berx 09-33.13.740

with the Princess Lilliane Cardiological Foundation

Dr. Patrick O. BROWN

Stanford University School of Medicine & Howard Hughes Medical Institute, Palo Alto, Stanford, USA

Searching for the dark matter of biological regulation”

283. Friday 30 May 2008

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Menno DEWINTHER

Department of Molecular Genetics, University Maastricht, The Netherlands

Macrophage function in atherogenesis

284. Friday 13 June 2008

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Helen SANG

Roslin Institute and Royal (Dick) School of Veterinary Studies, Midlothian, Scotland, UK

Applications of lentiviral vector transgenesis in chickens

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285. Thursday 19 June 2008

11h30-13h00

Host: K. Vleminckx 09-33.13.720

Dr. Alexis GAUTREAU

Laboratoire d’Enzymologie et de Biochimie Structurales, CNRS Gif-sur-Yvette cedex- France

In vivo assembly of functional Wave complexes

286. Friday 27 June 2008

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Vishva DIXIT

Molecular Oncology, Genentech Inc., San Francisco, USA

Ubiquitin modification & Innate immunity

287. Monday 7 July 2008

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Wolfgang DOSTMANN

Department of Pharmacology, College of Medicine, University of Vermont, Burlington, USA

The dynamics and differential patterning of intracellular cGMP

288. Friday 26 September 2008

11h30-13h00

Host: J.C. Marine 09-33.13.640

Dr. Lijian HUI

Research Institute of Molecular Pathology, Vienna, Austria

Functions of AP-1 (Jun/Fos) and MAPK (p38alpha/JNK) in hepatocellular carcinoma development

289. Wednesday 1 October 2008

11h30-13h00

Host: C. Chen 09-33.13.702

Dr. Aubrey de GREY

Methuselah Foundation, Cambridge, UK

Prospects for defeating aging altogether

290. Friday 3 October 2008

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Jeanette LEUSEN

Laboratory for Immunotherapy, University Medical Center Utrecht, Utrecht, The Netherlands

Biology of Fc receptors, consequences for antibody-therapy

291. Thursday 9 October 2008

11h30-13h00

Host: P.Vandenabeele 09-33.13.760

Dr. Jean MARTINEZ

Institut des Biomolécules Max Mouseron, Faculté de Pharmacie, Université de Montpellier, France

Amino acids and derivatives as attractive starting materials for the synthesis of biomolecules

292. Friday 10 October 2008

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Carme CAELLES

Cell Signalling Research Group, Institute for Research in Biomedicine, Barcelona, Spain

Negative crosstalk among nuclear receptors and the JNK signalling pathway: Mechanisms and actions

293. Monday 13 October 2008

17h00-18h00

Host: P.Vandenabeele 09-33.13.760

Dr. Mathieu BERTRAND

Center for Neuronal Survival, Montreal Neurological Institute, McGill University, Montreal, Canada

cIAPs are E3 ubiquitin ligases that modulate RIP1-dependent life and death decision

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294. Friday 17 October 2008

11h30-13h00

Host: P. Brouckaert 09-33.13.710

Dr. Erik MEULMEESTER

Department of Biochemistry I, University of Göttingen, Germany

Regulation and function of deubiquitinating enzymes

295. Friday 24 October 2008

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Ofer MANDELBOIM

The Hebrew University Hadassah Medical School, Jerusalem, Israel

Virus recognition by human NK cells: attack and counter attack

296. Friday 31 October 2008

11h30-13h00

Host: J. Haigh 09-33.13.730

Dr. Salvador AZNAR BENITAH

Epithelial Homeostasis and Cancer Lab, Dpt. Differentiation and Cancer, Center for Genomic Regulation, Barcelona, Spain

Transcriptional regulation of epidermal stem cells in skin homeostasis and cancer

297. Friday 7 November 2008

11h30-13h00

Host: G. Berx 09-33.13.740

Dr. Gabri VAN DER PLUIJM

Dept. Urology & Endocrinology, Leiden University Medical Center, The Netherlands

Tumor-bone interactions in the pathogenesis of bone metastasis

298. Friday 14 November 2008

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Rüdiger ARNOLD

German Cancer Research Center, Heidelberg, Germany

Role of NF-kB regulator HPK1 as a molecular switch between life and death in lymphocytes

299. Friday 21 November 2008

11h30-13h00

Host: G. van Loo 09-33.13.774

Dr. Diether LAMBRECHTS

VIB Vesalius Research Center, K.U.Leuven, Belgium

Novel roles of VEGF and its homologues in the (peripheral) nervous system

300. Friday 12 December 2008

11h30-13h00

Host: P. Vandenabeele 09-33.13.760

Dr. Karsten GÜLOW

German Cancer Research Center, Heidelberg, Germany

Inhibition of constitutively activated NF-kB induces ROS- and Iron-dependent cell death in Cutaneous T cell Lymphoma

301. Friday 16 January 2009

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Steve LEY

Division of Immune Cell Biology, National Institute for Medical Research, London, UK

Regulation of T cell activation by NF-kB1 p105

302. Monday 19 January 2009

11h30-13h00

Host: P.Vandenabeele 09-33.13.760

Dr. Nozomi TAKAHASHI

Laboratory of Experimental Rheumatology, Radboud University Medical Centre, Nijmegen, The Netherlands

Cytokine connection, innate immune signaling and gene expression: Defining the targets in inflammatory diseases

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303. Friday 23 January 2009

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Roosmarijn VANDENBROUCKE

DMBR – VIB – UGent (with work from the Laboratory of General Biochemistry, Fac. Pharmaceutical Sciences, UGent)

Non-viral delivery strategies to guide therapeutic nucleic acids through cellular barriers

304. Friday 30 January 2009

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Torik AYOUBI

Genome Center, University of Maastricht, The Netherlands

In silico dissection of cancer using gene expression microarrays and its application in personalized medicine

305. Friday 13 February 2009

11h30-13h00

Host: G. Berx 09-33.13.740

Dr. Nele HILGERT

DMBR – VIB – UGent (with work from the Department of Medical Genetics, University of Antwerp)

Identification of genes causing monogenic hearing impairment

306. Friday 20 February 2009

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. David MUYLLAERT

DMBR – VIB – UGent (with work from the Experimental Genetics Group, Department of Human Genetics, Faculty of Medicine, KULeuven)

Generation and validation of double transgenic mice as in vivo model for the synergism between amyloid and tau pathology in Alzheimer's disease

307. Tuesday 24 February 2009

11h30-13h00

Host: R. Beyaert & P. Vandenabeele 09-33.13.760 & 770

Dr. Nigel KILLEEN

Department of Microbiology and Immunology, University of California, San Francisco, USA

Tracing T Cell fate

308. Friday 27 February 2009

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Felix RANDOW

MRC Laboratory of Molecular Biology, Cambridge, UK

Genetics in mammalian cells to study innate immunity

309. Friday 6 March 2009

11h30-13h00

Host: K. Vleminckx 09-33.13.720

Dr. Roberto MAYOR

Department of Cell & Developmental Biology, University College London, UK

Contact inhibition as a new mechanism for directional migration of neural crest

310. Friday 27 March 2009

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Margot THOME-MIAZZA

Department of Biochemistry, University of Lausanne, Epalinges, Switzerland

Role of the protease activity of MALT1 in lymphocyte activation

311. Friday 3 April 2009

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Marie LE MERCIER

Laboratoire de Toxicologie, Université Libre de Bruxelles, Belgium

Galectin-1 in glioma biology

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312. Friday 17 April 2009

11h30-13h00

Host: W. Declercq 09-33.13.660

Dr. Jens-Michael SCHRÖDER

Klinische Forschergruppe "Kutane Entzündung", University Hospital Schleswig-Holstein, Kiel, Germany

Antimicrobial peptides: Effector molecules of the innate epithelial defense system

313. Friday 24 April 2009

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Thorsten WOLFF

Pathogenicity mechanisms of influenza viruses program Robert Koch-Institute, Berlin, Germany

Influenza viruses activate and inhibit the type I IFN response: From molecules to mechanism

314. Friday 8 May 2009

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. André GERBER

Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland

Global-scale analysis of RNA-protein interactions

315. Wednesday 13 May 2009

11h30-13h00

Host: J. Haigh 09-33.13.730

Dr. Viktor JANZEN

Department of Hematology and Oncology, University Hospital, Bonn, Germany

The impact of accelerated proliferation of hematopoietic stem cells on their self renewal ability

316. Friday 15 May 2009

11h30-13h00

Host: G. Berx 09-33.13.740

Dr. Riccardo FODDE Department of Pathology, Josephine Nefkens Institute, Erasmus University Medical Center, Rotterdam, The Netherlands

Cancer Stem Cells: are you an Anderlecht or Club Brugge supporter?

317. Friday 5 June 2009

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Dirk ELEWAUT

Department of Rheumatology, Ghent University Hospital, Belgium

Natural Killer T cells, a regulatory T cell lineage, bridging innate and adaptive immunity

318. Friday 12 June 2009

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Glenn RADICE

Center for Translational Medicine, Department of Medicine, Jefferson Medical College, Philadelphia PA, USA

Turning off the switch: New insights into N-cadherin function in cancer

319. Wednesday 17 June 2009

16h00-17h00

Host: C. Libert 09-33.13.700

Dr. R. Wilson POWERS III

Sterne, Kessler, Goldstein & Fox PLLC, Intellectual Property Washington DC, USA

Starvation, scalpels, drugs and life span extension: Reduced signaling through evolutionarily-conserved nutrient-sensing pathways slows aging

320. Monday 22 June 2009

12h00-13h00

Host: P.Vandenabeele 09-33.13.760

Dr. Boris TURK

Department of Biochemistry & Molecular & Structural Biology J. Stefan Institute, Ljubljana, Slovenia

What about: Lysosomes, cathepsins, cell death …

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321. Thursday 20 August 2009

15h00-16h00

Host: F. Van Roy 09-33.13.601

Dr. Panos ANASTASIADIS

Cell Adhesion and Metastasis, Department of Cancer Biology Mayo Clinic Comprehensive Cancer Center, Jacksonville FL, USA

The role of p120-cadherin complexes in anchorage-independent growth

322. Friday 2 October 2009

11h30-13h00

Host: F. Van Roy 09-33.13.601

Dr. Patrick DERKSEN

Dept. of Medical Oncology, UMC Utrecht, The Netherlands

Context-dependent roles for p120 in E-cadherin deficient breast cancer

323. Friday 9 October 2009

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Paloma PEREZ

Animal Models of Skin Pathologies Unit, Instituto de Biomedicina de Valencia, Spain

Functional analysis of the glucocorticoid receptor in cutaneous biology

324. Wednesday 14 October 2009

14h00-15h30

Host: W. Declercq 09-33.13.660

Dr. Ingo HAASE

Department of Dermatology, University of Cologne, Germany

Control of skin inflammation by epidermal keratinocytes

325. Wednesday 4 November 2009

11h30-13h00

Host: J. Grooten 09-33.13.650

Dr. Knut STEFFENSEN

Receptor Biology Unit, Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden

Oxysterol receptors – LXRs - are novel targets for the treatment of inflammatory diseases, metabolic diseases and cancer

326. Friday 16 October 2009

11h30-13h00

Host: N. Callewaert 09-33.13.601

Dr. Kris HUYGEN

Immunology & Vaccinology Section, Scientific Institute of Public Health, Brussels, Belgium

Potential of DNA vaccines for the prophylaxis of Mycobacterial diseases

327. Friday 13 November 2009 11h30-13h00

Host: J. Haigh 09-33.13.730

Dr. Fanny MANN

Institut de Biologie du Développement de Marseille-Luminy (IBDML - CNRS UMR 6216), Marseille, France

Building a brain: vascular molecules in nerve growth and connectivity

328. Friday 20 November 2009 11h30-13h00

Host: K. Vleminckx 09-33.13.720

Dr. André GOFFINET

Developmental Genetics Unit University of Louvain Medical School, Brussels

Planar cell polarity proteins Celsr1-3 and brain development

329. Thursday 26 November 2009

12h00-13h00

Host: P.Vandenabeele 09-33.13.760

Dr. David UCKER

Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, USA

Life after (cell) death

330. Friday 22 January 2010

11h30-13h00

Host: R. Beyaert 09-33.13.770

Dr. Mieke DELVAEYE

DMBR & DMPR – VIB – UGent (with work from the Vesalius Research Center, KULeuven)

Thrombomodulin mutations predispose to the development of aHUS via impaired complement regulation

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331. Friday 5 February 2010

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Dominique EMILIE

Cytokines, chemokines & immunopathology, UMR-S 764, INSERM/Université Paris-Sud, Clamart, France

Expression and function of the Glucocorticoid-induced leucin zipper (GILZ) in macrophages and dendritic cells

332. Friday 12 February 2010

11h30-13h00

Host: G. van Loo 09-33.13.774

Dr. David KOMANDER

MRC Laboratory of Molecular Biology, Cambridge, UK

Specificity of the 'signalling' OTU deubiquitinases

333. Thursday 18 February 2010

11h30-13h00

Host: C. Guérin 09-33.13.611

Joint seminar with VIB2-Department of Plant Systems Biology

Dr. Wim ANNAERT

VIB Department of Molecular and Developmental Genetics, K.U.Leuven, Belgium

Sorting out the cell biology of Alzheimer's disease

334. Friday 19 February 2010

16h00-17h00

Host: P.Vandenabeele 09-33.13.760

Dr. Christoph BORNER

Spemann Graduate School of Biology and Medicine, Institute of Molecular Medicine and Cell Research, Freiburg, Germany

Mr. Bax, Mrs. Bcl-2 and their dozen kids: A protein family on the edge of survival and death

335. Friday 26 February 2010

11h30-13h00

Host: P.Vandenabeele 09-33.13.760

Dr. Vanessa MORAIS

VIB Department of Molecular and Developmental Genetics, K.U. Leuven

Parkinson’s disease: PINK1 affects Complex I activity and synaptic function

336. Friday 12 March 2010

12h00-13h00

Host: G. Berx 09-33.13.740

Dr. Bob VAN DE WATER

Division of Toxicology, Leiden/Amsterdam Center for Drug Research Leiden University, The Netherlands

Functional genomics of tumor cell migration and mechanisms of metastasis formation

337. Tuesday 16 March 2010

11h30-13h00

Host: C. Libert 09-33.13.700

Dr. Holger REICHARDT

Cellular and Molecular Immunology, University of Göttingen Medical School, Göttingen, Germany

Beneficial and adverse effects of glucocorticoids

338. Thursday 18 March 2010

16h00-17h00

Host: J. Haigh 09-33.13.730

Dr. Jean-Pierre DAVID

Dept. of Internal Medicine 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, Germany

Elevated Fra-1 expression causes severe lipodystrophy in the osteosclerotic fra-1 transgenic mice

339. Friday 26 March 2010

11h30-13h00

Host: X. Saelens 09-33.13.620

Dr. Hans DOOMS

T-cell regulation in tolerance and immunity, Department of Pathology, University of California, San Francisco, USA

Autoreactive memory T cells in Type 1 Diabetes

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340. Monday 3 May 2010

11:30-12:30

Host: F. van Roy 09-33.13.601

Dr. Cord BRAKEBUSCH

Dept. Biomedical Sciences, BRIC - Biotech Research and Innovation Centre, University of Copenhagen, Denmark

Rac1 in skin cancer and skin inflammation

341. Friday 21 May 2010

11:30-13:00

Host: R. Beyaert 09-33.13.770

Dr. Jurgen RULAND

Third Medical Department, Technical University of Munich & Laboratory of Signaling in the Immune System, Helmholtz Zentrum München, Germany

ITAM receptor signaling in innate and adaptive immunity

342. Friday 28 May 2010

11:30-13:00

Host: R. Beyaert 09-33.13.770

Joint seminar with the FWO Research Network “Signal transduction in Inflammation and Immunity”

Sir Philip COHEN

College of Life Sciences, Sir James Black Centre, University of Dundee, Scotland, UK

The interplay between protein phosphorylation and protein ubiquitylation in regulating the innate immune system

343. Thursday 3 June 2010

15:30-16:30

Host: N. Callewaert 09-33.13.630

Dr. Douglas KERNODLE

Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville TN, USA

Improving BCG by targeting microbial enzymes that mediate immune evasion

344. Friday 4 June 2010

11:30-13:00

Host: R. Beyaert 09-33.13.770

Joint seminar with the FWO Research Network “Signal transduction in Inflammation and Immunity”

Dr. Shao-Cong SUN

Department of Immunology, The University of Texas M. D. Anderson Cancer Center, Houston TX, USA

Regulation of NF-kB and immune function by ubiquitination and deubiquitination

345. Thursday 10 June 2010

16:00-17:00

Host: F. Van Roy 09-33.13.601

Dr. Jan DE MEY

Equipe "Microtubules et Morphogenèse", C.N.R.S. - U.M.R.7100, Ecole Supérieure de Biotechnologie de Strasbourg, France

Asymmetric basal and planar cell polarities control intestinal crypt homeostasis

346. Friday 11 June 2010

11:30-12:30

Host: W. Declercq 09-33.13.660

Dr. Martin MEMPEL

Department of Dermatology and Allergy, Helmholtz Zentrum München & Technische Universität München, Germany

TLR-expression in human keratinocytes and the response to Staphylococcus aureus

347. Friday 25 June 2010

11:30-12:30

Host: P.Vandenabeele 09-33.13.760

Dr. John SILKE

Department of Biochemistry, La Trobe University, Melbourne, Australia

The Hitchhiker's Guide to TNF signalling

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348. Monday 12 July 2010

17:00

Host: P.Vandenabeele 09-33.13.760

Dr. Henning WALCZAK

Chair of Tumour Immunology, Division of Immunology and Inflammation, Imperial College London, Hammersmith Hospital, U.K.

Cell death and inflammation: New insights on signal transduction by TNF and TRAIL

349. Tuesday 13 July 2010

11:30

Host: P.Vandenabeele 09-33.13.760

Dr.Sven HORKE

Institute of Pharmacology, Johannes Gutenberg-University Mainz, Germany

The anti-oxidative enzyme PON2: protector against atherosclerosis and bacterial infections, but traitor when it comes to cancer

350. Thursday 12 August 2010

14:00

Host: X. Saelens 09-33.13. 260

Dr. Annelies CRABBE

Interdepartementaal Stamcelinstituut Leuven, Belgium

Neuroectodermal differentiation of multipotent and pluripotent stem cells and their role in an animal model of stroke

351. Monday 6 September 2010

10:00

Host: P. Vandenabeele 09-33.13. 760

Dr. Marie-Thérèse DIMANCHE-BOITREL

IRSET - Institut de Recherche en Santé-Environnement-Travail. Department Signaling and responses to stress. Faculté de Pharmacie, Université Rennes 1, France.

“Alterations of extracellular or intracellular pH homeostasis: potential role in cell death induction.”

352. Thursday 30 September 2010

16:00

Host: W. Declercq 09-33.13. 260

Dr. Marja MIKKOLA

Developmental Biology Program, Institute of Biotechnology, University of Helsinki, Finland

“Skin appendage development: insights from the Eda/NF-kappaB pathway”

353. Thursday 7 October 2010

16:00

Host: X. Saelens 09-33.13. 260

Dr. Mikhail MATROSOVICH

Institute of Virology, Philipps University, Marburg, Germany

“Molecular analysis of Influenza A virus receptor specificity”

354. Monday 18 October 2010

11:30

Host: X. Saelens 09-33.13. 260

Dr. Jon Wilson YEWDELL

Laboratory of Viral Diseases, Cellular Biology and Viral Immunology Section, National Institute of Allergy and Infectious Diseases, Bethesda MD, USA

“Influenza antigenic drift: New look at an old phenomenon”

355. Idem

16:00

Dr. Jon Wilson YEWDELL

Ibidem

Advice talk: “How to succeed in science?”

356. Thursday 21 October 2010

16:00

Host: K. Vleminckx 09-33.13.760

Dr. Enrique AMAYA

The Healing Foundation Centre, Faculty of Life Sciences, University of Manchester, UK

“The inflammatory response during embryonic wound healing”

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357. Monday 25 October 2010

11:30

Host: F. Van Roy 09-33.13.601

Joint seminar with the FWO Research Network “Cell-cell and cell-matrix interactions”

Dr. Masatoshi TAKEICHI

Laboratory for Cell Adhesion and Tissue Patterning, Director of the RIKEN Center for Developmental Biology, Kobe, Japan

“Interplay of cadherin and cytoskeletons to regulate cell-cell junctions”

358. Thursday 28 October 2010 16:00

Host: P. Vandenabeele 09-33.13.760

Dr. Valerian KAGAN

Center for Free Radical and Antioxidant Health, Department of Environmental and Occupational Health, University of Pittsburgh, USA, and Russian State Medical University, Moscow, Russia

“Redox biochemistry of apoptosis as a matter of Fa(c)t”

359. Thursday 18 November 2010 16:00

Host: X. Saelens 09-33.13.620

Dr. Jose Antonio MELERO

National Microbiology Institute in Madrid, Spain

“Substantial mechanistic differences between the fusion protein of respiratory syncytial virus and homologous proteins of other paramyxoviruses”

360. Monday 22 November 2010 16:00

Host: F. Van Roy 09-33.13.601

Dr. Gerry MELINO

Apoptosis and Cancer, MRC Toxicology Unit, University of Leicester, U.K. and University of Tor Vergata, Rome, Italy.

“p73 and cancer”

361. Thursday 25 November 2010 16:00

Host: B. Lambrecht

UGent Seminar @ VIB

Dr. Sofia BUONOCORE

GlaxoSmithKline Biologicals, Rixensart, Belgium

"IL-23 axis in intestinal inflammation" 362. Thursday

2 December 2010 16:00

Host: F. Van Roy 09-33.13.601

Dr. John HISCOTT

Department of Molecular Oncology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada

“RIG-like Receptors: Sensing and responding to Virus Infection”

363. Thursday 9 December 2010 16:00

Host: C. Libert 09-33.13.700

Dr. Bénédicte CAUWE

Rega Instituut, K.U. Leuven, Belgium

“Proteolysis of systemic autoantigens and suppression of systemic autoimmunity by gelatinase B/MMP-9”

364. Thursday 20 January 2011 16:00

Host: K. Vleminckx 09-33.13.720

Dr. Fabian SCHNEIDER

Institute of Neurology (Edinger-Institute), Johann Wolfgang Goethe-University Frankfurt, Germany

“Interaction of Hedgehog and Wnt/β-catenin signaling in the adult tongue epithelium”

365. Thursday 3 February 2011 16:00

Host: G. van Loo 09-33.13.645

Dr. Johan VAN ES

Hubrecht Institute for Developmental Biology and Stem Cell Research, and University Medical Centre Utrecht, The Netherlands

“Wnt signaling, Lgr5 Stem Cells and Cancer: Lessons from genetically modified mice and a unique culture system”

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366. Thursday 10 February 2011 16:00

Host: G. van Loo 09-33.13.645

Dr. Andy WULLAERT

Pasparakis Lab, Institute for Genetics, Cologne, Germany

“Epithelial NF-kappaB signalling in intestinal immune homeostasis”

367. Friday 11 February 2011 16:00

Host: F. Van Roy 09-33.13.601

Dr. Marc STEMMLER

Dept. Molecular Embryology, Max-Planck Institute of Immunobiology, Freiburg, Germany

“E-cadherin and N-cadherin during development and tumor progression”

368. Thursday 24 February 2011 16:00

Host: C. Libert 09-33.13.700

Dr. Carlo RICCARDI

Section of Pharmacology Toxicology and Chemotherapy, Department of Clinical and Experimental Medicine, University of Perugia, Italy

“Molecular mechanisms of glucocorticoids: role of GILZ”

369. Monday 28 February 2010 16h00-17h00

Host: B. Lambrecht & H. Hammad 09-33.28.784

UGent Seminar @ VIB : MRP seminar (GROUP-ID consortium)

Dr. Hajime KARASUYAMA

Department of Immune Regulation, Tokyo Medical and Dental University Graduate School, Japan

“Emerging roles of basophils in allergy and protective immunity: a neglected minority gains new respect”

370. Thursday 1 April 2011 11:30

Host: C. Libert 09-33.13.700

Dr. Ian ADCOCK

Cell & Molecular Biology, Airways Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, U.K.

“Overcoming corticosteroid insensitivity in airways disease”

371. Thursday 7 April 2011 16:00

Host: W. Declercq 09-33.13.660

Dr. Michael MILDNER

Department of Dermatology, University of Vienna, Austria

“Secretome of apoptotic peripheral blood cells confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction”

372. Wednesday 13 April 2011 11:00

Host: W. Declercq 09-33.13.660

Dr. David DOMBROWICZ

Université Lille - Nord de France & Institut Pasteur de Lille, France

“Role of fractalkine in atopic dermatitis and allergic asthma”

373. Thursday 14 April 2011 16:00

Host: N. Callewaert 09-33.13.630

Dr. Ewald PAUWELS Interfacultary Research Center for Molecular Modeling (CMM) of Ghent University, Zwijnaarde, Belgium

“Molecular modeling: protein folding, dynamics and reactions at the atomic scale”

374. Thursday 28 April 2011 16:00

Host: G. van Loo 09-33.13.645

Dr. Etienne MEYLAN

Swiss Institute for Experimental Cancer Research (ISREC), Ecole Polytechnique Fédérale de Lausanne, Switzerland

“Exploration of NF-kB signaling in lung adenocarcinoma”

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375. Monday 2 May 2011 16:00

Host: K. Vleminckx 09-33.13.720

Dr. François FAGOTTO

Department of Biology, McGill University, Montreal, Quebec, Canada

“Cell-cell contact-dependent signaling through ephrins/Eph and EpCAM controls tissue integrity/invasion during early embryonic development”

376. Thursday 5 May 2011 16:00

Host: N. Callewaert 09-33.13.620

Dr. Ben APPELMELK

Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands

“Ligands galore! Pathogenic mycobacteria express many DC-SIGN ligands”

377. Thursday 12 May 2011 16:00

Host: X. Saelens 09-33.13.620

Dr. Paul DIGARD

Division of Virology, Department of Pathology, University of Cambridge, U.K.

“New genes in an old virus: hidden surprises in the influenza A genome”

378. Monday 30 May 2011 17:00

Host: P. Vandenabeele 09-33.13.760

Dr. Pascal MEIER

The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, Chester Beatty Laboratories, London, UK.

“Ubiquitin-mediated regulation of cell survival”

379. Tuesday 7June 2011 16:00

Host: R. Beyaert 09-33.13.770

Dr. Noula SHEMBADE

Department of Microbiology and Immunology, Miller School of Medicine, Sylvester Comprehensive Cancer Center, University of Miami, Florida, USA

“Negative regulation of NF-kB and inflammation”

380. Thursday 9 June 2011 16:00

Host: J. Haigh 09-33.13.730

Dr. Axel BEHRENS

Cancer Research UK, the London Research Institute, Lincoln's Inn Fields Laboratories, London, UK

“Transcriptional control in stem cells and cancer”

381. Thursday 16 June 2011 16:00

Host: X. Saelens 09-33.13.620

Dr. Max MAZZONE

Molecular Oncology and Angiogenesis, Vesalius Research Center, VIB & K.U.Leuven, Belgium

“PHD2 oxygen sensor: a gateway system in angiogenenesis and arteriogenesis”

382. Wednesday 22 June 2011 16:00

Host: J. Haigh 09-33.13.730

Dr. Maxime BOUCHARD

McGill Cancer Centre and Biochemistry Department, McGill University, Montreal, Quebec, Canada

“Development and cancer of the genitourinary system”

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383. Thursday 23 June 2011 16:00

Host: P. Brouckaert 09-33.13.710

Dr. Emmanuel BUYS

Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Management, Massachusetts General Hospital and Harvard Medical School, Boston MA, USA

“sGC: from hypertension to glaucoma”

384. Thursday 7 July 2011 16:00

Host: C. Libert 09-33.13.700

Dr. Roel STERKEN

Division of Nephrology, Columbia University, New York, USA

“An integrative genomics approach to HIV associated nephropathy”

385. Thursday 1 September 2011 16:00

Host: X. Saelens 09-33.13.620

Dr. Kirsty SHORT

Department of Microbiology and Immunology, University of Melbourne, Australia

“A killer combination: The role of influenza virus in bacterial disease and transmission”

386. Tuesday 6 September 2011 11:30

Host: J. Haigh 09-33.13.730

Dr. Helen ABUD

Department of Anatomy & Cell Biology, Faculty of Medicine, Nursing & Health Sciences, Monash University, Victoria, Australia

“Functional analysis of Snail proteins in the intestinal stem cell niche”

387. Thursday 8 September 2011 16:00

Host: B. Lambrecht & H. Hammad 09-33.28.784

UGent Seminar @ VIB : MRP seminar (GROUP-ID consortium)

Dr. Paul KIRKHAM

National Heart & Lung Institute, Imperial College London, Royal Brompton Hospital, London, UK

“Carbonyl stress and inflammation”

388. Monday 23 September 2011 11:30

Host: G. Berx 09-33.13.740

Dr. Jonathan SLEEMAN

Microvascular Biology and Pathobiology Center for Biomedicine and Medicical Technology Medical Faculty Mannheim, University of Heidelberg, Germany

“The contribution of the lymphatic system to metastatic spread”

389. Friday 7 October 2011 11:30

Host: R. Beyaert 09-33.13.770

Dr. Zoltan FEHERVARI

Associate Editor of Nature Immunology, London, U.K.

“How to get published”

390. Friday 14 October 2011 11:30

Host: P. Vandenabeele 09-33.13.760

Dr. Pietro GHEZZI

Brighton and Sussex Medical School, Trafford Centre, Falmer, Brighton, U.K.

“EPO and tissue protection/repair”

391. Friday 4 November 2011 11:30

Host: C. Libert 09-33.13.700

Dr. Elisabeth R. BARTON

Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, USA

“Muscle production of insulin-like growth factor-I, a matter of form and function”

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392. Tuesday 8 November 2011 11:00

Host: R. Beyaert 09-33.13.770

Dr. Karine ROGET

Division of Immune Cell Biology, National Institute for Medical Research, London, UK

“Identification of kinase regulators of the TPL-2 / ERK MAP kinase signalling pathway”

393. Thursday 10 November 2011 16:00

Host: B. Lambrecht 09-33.28.784

UGent Seminar @ VIB : MRP seminar (GROUP-ID consortium)

Dr. Peter ASKENASE

Section of Allergy and Clinical Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven CT, USA

“Suppressor T cell antigen specific exosomes target distant effector T cells via inhibitor miRNA cargo”

394. Thursday 17 November 2011 16:00

Host: P. Brouckaert 09-33.13.710

Dr. Amrita AHLUWALIA

William Harvey Research Institute, Barts and The London, Queen Mary's School of Medicine and Dentistry, London, UK

“A 'reductionist' approach to cardiovascular disease: nitrate to nitrite to NO”

395. Monday 21 November 2011 11:30

Host: J. Haigh 09-33.13.730

Dr. Colin D. FUNK

Canada Research Chair in Molecular, Cellular and Physiological Medicine, Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, Canada

“Lipoxygenase and leukotriene pathways in health and disease” 396. Friday

25 November 2011 11:30

Host: C. Libert 09-33.13.700

Dr. Carsten CARLBERG

Department of Biosciences/Biochemistry Unit, University of Eastern Finland, Kuopio, Finland

“Genome-wide view on nuclear receptor signalling”

397. Monday 5 December 2011 16:00

Host: R. Beyaert 09-33.13.770

Dr. Bram van RAAM

Salvesen lab, Sanford-Burnham Medical Research Institute, La Jolla CA, USA

“Caspase-8 vs. Caspase-6: Apoptosis and beyond” 398. Thursday

8 December 2011 16:00

Host: B. Lambrecht 09-33.28.784

UGent Seminar @ VIB : MRP seminar (GROUP-ID consortium)

Dr. Ebo DE MUINCK

Department of Cardiovascular Medicine, Faculty of Health Sciences, University of Linköping, Sweden

“Dendritic cells regulate inflammation, angiogenesis and wound healing after myocardial infarction”

399. Friday 9 December 2011 11:30

Host: P. Brouckaert 09-33.13.710

Dr. Harald SCHMIDT

Department of Pharmacology, Maastricht University, Maastricht, The Netherlands

“Oxidative stress at last: Sources, targets and therapeutic implications”

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400. Monday 12 December 2011 11:30

Host: B. Lambrecht 09-33.28.784

Dr. Andrew S. McDONALD

MRC Senior Fellow, Institute of Immunology and Infection Research, School of Biological Sciences,University of Edinburgh, Schotland, U.K.

“The importance of dendritic cells during parasitic helminth infection” 401. Thursday

15 December 2011 16:00

Host: B. Lambrecht 09-33.28.784

UGent Seminar @ VIB : MRP seminar (GROUP-ID consortium)

Dr. Patrizia AGOSTINIS

Department of Molecular Cell Biology, Cell Death Research and Therapy Laboratory, Catholic University of Leuven, Belgium

“Unfolding the role of PERK in cancer cell death”