dna (deoxyribonucleic acid)

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DNA (Deoxyribonucleic Aci History and Struc C10L28C12

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DNA (Deoxyribonucleic Acid). History and Structure. C10L28C12. Chromosomes and DNA. During Mitosis we can see Chromosomes. Chromosomes are made of DNA. Chromosomes and DNA. Today’s Goals. Item 1. Item 2. DNA History. DNA Structure. What is DNA?. DNA Nitrogen Bases. Chargaff's Rule. - PowerPoint PPT Presentation

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Page 1: DNA (Deoxyribonucleic Acid)

DNA(Deoxyribonucleic Acid)History and Structure

C10L28C12

Page 2: DNA (Deoxyribonucleic Acid)

During Mitosis we can see Chromosomes

Chromosomes and DNA

Chromosomes are made of

DNA

Page 3: DNA (Deoxyribonucleic Acid)

Chromosomes and DNA

Page 4: DNA (Deoxyribonucleic Acid)

Item 5

DNA HistoryDNA Structure

Today’s Goals

What is DNA?

DNA Nitrogen BasesChargaff's Rule

Item 1Item

2Item 3Item

4

Page 5: DNA (Deoxyribonucleic Acid)

DNA holds all the genetic information that determines an

organism’s traits.

What is DNA?

Hair Color

Eye Color

Height

Skin Tone

Page 6: DNA (Deoxyribonucleic Acid)

Within the structure of DNA is the information for life—the complete instructions for manufacturing all

the proteins for an organism.

What is DNA?

o DNA achieves its control by determining the structure of proteins.

* Enzymes (a type of protein) control the chemical reactions needed for life.• Eating, running, even thinking

Page 7: DNA (Deoxyribonucleic Acid)

Item 5

DNA HistoryDNA Structure

Today’s Goals

What is DNA?

DNA Nitrogen BasesChargaff's Rule

Item 1Item

2Item 3Item

4

Page 8: DNA (Deoxyribonucleic Acid)

Important clues to the structure of DNA

1. Twisted strands (helix)2. Angle suggested 2

strands ( double-helix)3. Nitrogen bases near the

center of the molecule

Rosalind FranklinStudied DNA structure with X-ray diffraction

1952

Page 9: DNA (Deoxyribonucleic Acid)

James Watson

and Francis CrickBuilt a DNA model based on

the clues from Franklins X-ray diffraction

1953

Page 10: DNA (Deoxyribonucleic Acid)

Item 5

DNA HistoryDNA Structure

Today’s Goals

What is DNA?

DNA Nitrogen BasesChargaff's Rule

Item 1Item

2Item 3Item

4

Page 11: DNA (Deoxyribonucleic Acid)

DNA is a Double HelixA double helix looks like a twisted ladder.

Page 12: DNA (Deoxyribonucleic Acid)

The Double Helix Building Blocks

A DNA strand is a polymer.

They are very long!It’s length is what allows DNA

to hold so much information

The repeating subunits of DNA are called

nucleotides

Page 13: DNA (Deoxyribonucleic Acid)

Nucleotide StructureComposed of 3 parts

Phosphate

DeoxyriboseSugar

NitrogenBase

•There are 4 possible bases.•Broken down into 2 categories

Page 14: DNA (Deoxyribonucleic Acid)

Nucleotide Structure• The phosphate

groups and deoxyribose (sugar) molecules bond to form the backbone of the chain

• The nitrogenous bases stick out like the teeth of a zipper.

Page 15: DNA (Deoxyribonucleic Acid)

Item 5

DNA HistoryDNA Structure

Today’s Goals

What is DNA?

DNA Nitrogen BasesChargaff's Rule

Item 1Item

2Item 3Item

4

Page 16: DNA (Deoxyribonucleic Acid)

PURINESPurines have two

ringsPyrimadines have

one ring

PYRIMIDINES

Types of Nitrogen basesThere are two types of nitrogen bases

Page 17: DNA (Deoxyribonucleic Acid)

PURINES

PYRIMIDINES

Types of Nitrogen basesThere are two types of nitrogen bases

Page 18: DNA (Deoxyribonucleic Acid)

Item 5

DNA HistoryDNA Structure

Today’s Goals

What is DNA?

DNA Nitrogen BasesChargaff's Rule

Item 1Item

2Item 3Item

4

Page 19: DNA (Deoxyribonucleic Acid)

How the double helix is formed

Nitrogen bases bond to one another to connect the two strands

But only certain bases can bond to one another

Page 20: DNA (Deoxyribonucleic Acid)

1 PURINE MUST BOND TO 1 PYRIMADINE

Guanine only bonds to

Cytosine

Chargaff’s Rule – Base Pairing

Adenine only bonds to

ThymineAt The

Grand Canyon

Page 21: DNA (Deoxyribonucleic Acid)

OVERVIEW