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NP are considered substances that are less than 100 nm in size in more than one nm. They can be spherical, tubular, or irregularly shaped and can exist in fused, aggregated or agglomerated forms.
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Natural 1. C-containing fulvic acids2. Inorganic Ag, Au Anthropogenic( Anthropogenic
engineered)1. C-containing Polyethyleneglycol (PEG)
NP2. Inorganic Platinum group metals
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efficacy of nanoparticles for any application dependson the physicochemical characteristics of both their core material and surface modifiers.
Nanomaterials are excellent adsorbents, catalysts, and sensors due to their large specific surface area and high reactivity.
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Antioxidant Bactericides Enzymes immobilization: free lipases
are easily inactivated and difficult to recover for reuse. Therefore, especially in large-scale applications, lipases are often immobilized on solid supports in order to facilitate recovery and improve operational stability under a wide variety of reaction conditions
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anti-glycation activity of gold nanoparticles in addition to their biocompatibility has made them preferable for ophthalmological implications
Single enzyme Nanoparticles:
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Acetylcholinesterase (AChE) & acetylcholinesterase inhibitor (AChEI) Monocrotophos.
fibril formation
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Heavy metals deactivation and denaturation
Competitive inhibition gold nanoparticles colloids can be used in
diagnosis and treatment of some kinds of cancer
gold and silver nanoparticles colloids on activities of the different enzymes.
gold and silver nanoparticles colloids inhibition of GPT and GOT enzymes
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In animal models nanosilver alters the expression of matrix metallo-proteinases.
b-Lactamases (Blas) inhibitory effect of the nanoparticles on
growth of gram negative bacteria.
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disrupt normal protein function suppression of energy metabolism oxidative damage to crucial proteins and
enzymes and increased membrane permeability,
causing its rupture
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nanoparticles themselves directly exert toxicities.
nanoparticles can be used as delivery carriers.