Healthgrid Systems Experiences from International Projects
David MANSETDirector of Biomedical ApplicationsCEO MAAT Francewww.maat-g.com
Idea DevelopmentStart-Up
1998- Stage 1 2000- Stage 2 2004- Stage 3 2007- Stage 4
Growth
Foundation Process
Virtual Knowledge & Maat Gknowledge Incubation, I+D+i, Raising Public Awareness
Maat Gknowledge Internationalization
Partners Network
maat – Stages of Growth
maat Portfolio (1)
Horizontal Solutions
Data Warehouse
Grid Integration
SaaS
maat Portfolio (2)
SM
Es
- ER
P
Vertical Solutions
Ban
king
Is about Core Banking
- Integrated transactional banking system
- CRM,- Wealth management,- Corporate banking,- Trade Finance,- Functional services
Edu
catio
nP
ublic
Adm
inis
tratio
n
Is about e-Administration
- Faciliate access to information,
- Electronic access points,- Security and privacy on
citizens data,- System interoperability,- eServices to citizens
such as electronic transactions,
- Compliant with LAECAP law
gemagrid
RA
D W
ebH
ealth
care
Is about Healthcare ICT
- Research infrastructure,- Multi-level data
integration,- Multi-centre network,- Security and privacy
conformance,- Multi-backends
abstraction,- DICOM compliant
Service Utility
ServiceUtility
ServiceUtility
Knowledge
Data
Services
Knowledge
Data
Services
Grid
maat Portfolio (3)
gemagrid
An Inter-Disciplinary Middleware-Agnostic Web Operating System
maat Portfolio (3)
*Courtesy of SIEMENS
Awards in 1 Year Time..
maat received a “Gold Medal” Award at the 2007 “Salon International des Inventions de Genève” for its prototype Healthgrid Platform
HeC/maat ranked 1st Best Live Demo at the 2008 EGEE User Forum, February in Clermont-Ferrand, France for its Healthgrid Platform and Innovative Applications
HeC/maat ranked in Top 5 Best Live Demos, qualified as “Runners Up”at the 2007 EGEE Conference last October in Budapest , Hungary for its Healthgrid Platform
HeC/maat ranked 1st Best Live Demo at the 2008 HealthGrid Conference, June in Chicago, US
HeC/maat won Grand Prize - Best Exhibit 1st Prizeat the 2008 ICT Conference, November in Lyon, France
10’000€
Healthgrid (1)
The Internet, the Web and the GRID
Internet
The worldwide network of networks...
Web
The protocol for sharing Information over the Internet...
Grid
The environment for sharing
computing resources over the W
eb...
*Courtesy of EGEE Project
Portal
(A series of *web* interfaces exposing the functionality to end-users from login, to data acquisition, quality control, Workflow authoring ... and much more! The Portal approach beyond accessibility advantages, allows harmonizing the software offer)
Business Logic(NeuroSciences Specific Services)
Domain Logic(Medical Generic Services)
Security
(All services concerned w
ith authentication, authorization w
ithin the neuGR
ID platform
)
Backends Abstraction(Software abstraction from databases, grid, enactment environments...)
System Architecture (1/2)
Backends Middleware(Underlying IT legacy assets, e.g. EGEE gLite, mySQL, LONI, Oracle 11g...)
Monitoring, Logging and A
ccounting(P
rovides the mechanism
s to store, archive and sort all log information.
The layer is concerned with services w
hich allow efficient m
onitoring of all infrastructure resources , and from
which higher level logic such
as Provenance can extract useful historical data)
Workflow
Managem
ent(S
OA G
overnance is in charge of defining, accessing,executing, operating and m
aintaining reusable services w
ith appropriate quality of services and conforming w
ithall other requirem
ents, e.g. Security, privacy...)
Privacy
(All services necessary to guaranty privacy
Over m
edical data storage, access and S
haring. Privacy related services m
ust conform
with ethical E
U/N
ational regulations)
Layered View & Concepts
Portal
(A series of *web* interfaces exposing the functionality to end-users from login, to data acquisition, quality control, Workflow authoring ... and much more! The Portal approach beyond accessibility advantages, allows harmonizing the software offer)
Business Logic(NeuroSciences Specific Services)
Domain Logic(Medical Generic Services)
Security
(All services concerned w
ith authentication, authorization w
ithin the neuGR
ID platform
)
Backends Abstraction(Software abstraction from databases, grid, enactment environments...)
Backends Middleware(Underlying IT legacy assets, e.g. EGEE gLite, mySQL, LONI, Oracle 11g...)
Monitoring, Logging and A
ccounting(P
rovides the mechanism
s to store, archive and sort all log information.
The layer is concerned with services w
hich allow efficient m
onitoring of all infrastructure resources , and from
which higher level logic such
as Provenance can extract useful historical data)
Workflow
Managem
ent(S
OA G
overnance is in charge of defining, accessing,executing, operating and m
aintaining reusable services w
ith appropriate quality of services and conforming w
ithall other requirem
ents, e.g. Security, privacy...)
Privacy
(All services necessary to guaranty privacy
Over m
edical data storage, access and S
haring. Privacy related services m
ust conform
with ethical E
U/N
ational regulations)
Layered View & Concepts
Generic to ALL domains(can theoretically be fully reused)
Generic to Medical domain(can theoretically be reused in other medical applications)
Specific to Project(can theoretically be partly reused since
abstracted from underlying IT)
Common PurposeInterfaces
Highly SpecializedInterfaces
System Architecture (2/2)
Mammogrid+A Grid-powered Mammography Database
Healthgrid (1)
Oncology•Breast Cancer (micro-calcifications and masses)
Hea
lthgr
id
• Second Opinion• Cancer Screening• Education and Training• Reference Database / Repository
neuGRIDA Grid-based e-Infrastructure for Data Archiving and
Computing Intensive Applications in neurosciences
Healthgrid (2)
QuestionA Marker of Alzheimer’s progression?
Neurology•Degenerative diseases
Hea
lthgr
id
• Biomarkers Assessment• Biomarkers Authoring• Extension to Other Medical Areas• Reference Database & Infrastructure
Pharmaco-EpidemiologyMulti-centre Pharma Grid-based
Data Warehouse for Epidemiological Studies
Healthgrid (3)
Pharmacology Hea
lthgr
id
• Epidemiological Studies• Scalable Dataware House• Scalable Statistical Analysis
• Translational Research• Reference Database
Health-e-Child, An Healthgrid for Paediatrics
Healthgrid (4)
Cardiology•Tetralogy of Fallot (ToF)•Cardiomyopathy (HCM, DCM)
Rheumatology•Juvenile Idiopathic Arthritis (JIA)
NeuroOncology•Brain Tumors – Gliomas
Hea
lthgr
id
• Decision Support• Vertical Data Integration• Knowledge Discovery• Reference Database of Rare Conditions
SENTINELLE NetworkBreast and Colon Cancer Screening,
Surveillance Network
Healthgrid (5)
Hea
lthgr
id
• Breast Cancer Screening • Colon Cancer Screening• Surveillance, Alert and Monitoring Network
SPIDeRSuper Peta-scale Infrastructure for
Distributed e-health and biomedical Research
Healthgrid (6)
Hea
lthgr
id
Neurology
Epidemiology
Drug Development
http://spider.healthgrid.org
Silken Bags
Silk Collaborations
SPIDeR WebA Super Infrastructure of about
- 6000 CPUs, - 100TB, - 15 new dedicated sites
GOSHUWE
IGG
SIEMENS
ASPER
UOA
INRIALYNKEUS
UCL
EGFFGG
MAAT
Clinical Site
R&D Site
+
DISIINDRA
PRODEMA
CERN
KI
VUmc
CETA
CIEMAT HG
CFC
Infrastructure
+MAAT
NECKER
FBF
+
++
OPBG+
++
JHU
SIEMENS++
MAAT COL
+
Healthgrid
DSS Paediat. Cancer Alzheimer BiomarkerCADe Breast Cancer20062005 2008
UWE
Mam
mog
rid+
Hea
lth-e
-Chi
ld
neuG
RID
+++++
Healthgrid
Marketing Plan (1)
Marketing Plan (2)
Healthgrid
+++++
DSS Paediat. Cancer Alzheimer BiomarkerCADe Breast CancerA Network of Certified Partners
- Support in porting new applications to HGSP- Online & Offline education services- OnDemand infrastructure and data for application training
- Access to infrastructure facilities for promoting new products- Direct access to market (i.e. Network of Clinical Institutions)
- Certification process and official label for software- Possibility to sell online consultancy
- Education careers: technicial (presales, maintenance and support, and operation) and sales/marketing
A Network of Clinical Institutions- User Support
- Online & Offline Education Services (from HGSP and from Certified Partners)
- Access to a large network of excellence at minimal cost- Access to state-of-the-art software from Certified Partners- Provide data for enriching the infrastructure
Infrastructure- Teaming-up with Telco Operators (i.e. Telefonica)
- Sustainable platform and infrastructure- Strong position in the market and its big sales network (not only in Spain but worldwide)
- Opened infrastructure to Consultancy and Systems Integrator firms (i.e. Indra, Entel)
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THANK YOU FOR YOUR ATTENTION!