Healthgrid Systems Experiences from International Projects

David MANSETDirector of Biomedical ApplicationsCEO MAAT Francewww.maat-g.com

Idea DevelopmentStart-Up

1998- Stage 1 2000- Stage 2 2004- Stage 3 2007- Stage 4

Growth

Foundation Process

Virtual Knowledge & Maat Gknowledge Incubation, I+D+i, Raising Public Awareness

Maat Gknowledge Internationalization

Partners Network

maat – Stages of Growth

maat Portfolio (1)

Horizontal Solutions

Data Warehouse

Grid Integration

SaaS

maat Portfolio (2)

SM

Es

- ER

P

Vertical Solutions

Ban

king

Is about Core Banking

- Integrated transactional banking system

- CRM,- Wealth management,- Corporate banking,- Trade Finance,- Functional services

Edu

catio

nP

ublic

Adm

inis

tratio

n

Is about e-Administration

- Faciliate access to information,

- Electronic access points,- Security and privacy on

citizens data,- System interoperability,- eServices to citizens

such as electronic transactions,

- Compliant with LAECAP law

gemagrid

RA

D W

ebH

ealth

care

Is about Healthcare ICT

- Research infrastructure,- Multi-level data

integration,- Multi-centre network,- Security and privacy

conformance,- Multi-backends

abstraction,- DICOM compliant

Service Utility

ServiceUtility

ServiceUtility

Knowledge

Data

Services

Knowledge

Data

Services

Grid

maat Portfolio (3)

gemagrid

An Inter-Disciplinary Middleware-Agnostic Web Operating System

maat Portfolio (3)

*Courtesy of SIEMENS

Awards in 1 Year Time..

maat received a “Gold Medal” Award at the 2007 “Salon International des Inventions de Genève” for its prototype Healthgrid Platform

HeC/maat ranked 1st Best Live Demo at the 2008 EGEE User Forum, February in Clermont-Ferrand, France for its Healthgrid Platform and Innovative Applications

HeC/maat ranked in Top 5 Best Live Demos, qualified as “Runners Up”at the 2007 EGEE Conference last October in Budapest , Hungary for its Healthgrid Platform

HeC/maat ranked 1st Best Live Demo at the 2008 HealthGrid Conference, June in Chicago, US

HeC/maat won Grand Prize - Best Exhibit 1st Prizeat the 2008 ICT Conference, November in Lyon, France

10’000€

Healthgrid (1)

The Internet, the Web and the GRID

Internet

The worldwide network of networks...

Web

The protocol for sharing Information over the Internet...

Grid

The environment for sharing

computing resources over the W

eb...

*Courtesy of EGEE Project

Portal

(A series of *web* interfaces exposing the functionality to end-users from login, to data acquisition, quality control, Workflow authoring ... and much more! The Portal approach beyond accessibility advantages, allows harmonizing the software offer)

Business Logic(NeuroSciences Specific Services)

Domain Logic(Medical Generic Services)

Security

(All services concerned w

ith authentication, authorization w

ithin the neuGR

ID platform

)

Backends Abstraction(Software abstraction from databases, grid, enactment environments...)

System Architecture (1/2)

Backends Middleware(Underlying IT legacy assets, e.g. EGEE gLite, mySQL, LONI, Oracle 11g...)

Monitoring, Logging and A

ccounting(P

rovides the mechanism

s to store, archive and sort all log information.

The layer is concerned with services w

hich allow efficient m

onitoring of all infrastructure resources , and from

which higher level logic such

as Provenance can extract useful historical data)

Workflow

Managem

ent(S

OA G

overnance is in charge of defining, accessing,executing, operating and m

aintaining reusable services w

ith appropriate quality of services and conforming w

ithall other requirem

ents, e.g. Security, privacy...)

Privacy

(All services necessary to guaranty privacy

Over m

edical data storage, access and S

haring. Privacy related services m

ust conform

with ethical E

U/N

ational regulations)

Layered View & Concepts

Portal

(A series of *web* interfaces exposing the functionality to end-users from login, to data acquisition, quality control, Workflow authoring ... and much more! The Portal approach beyond accessibility advantages, allows harmonizing the software offer)

Business Logic(NeuroSciences Specific Services)

Domain Logic(Medical Generic Services)

Security

(All services concerned w

ith authentication, authorization w

ithin the neuGR

ID platform

)

Backends Abstraction(Software abstraction from databases, grid, enactment environments...)

Backends Middleware(Underlying IT legacy assets, e.g. EGEE gLite, mySQL, LONI, Oracle 11g...)

Monitoring, Logging and A

ccounting(P

rovides the mechanism

s to store, archive and sort all log information.

The layer is concerned with services w

hich allow efficient m

onitoring of all infrastructure resources , and from

which higher level logic such

as Provenance can extract useful historical data)

Workflow

Managem

ent(S

OA G

overnance is in charge of defining, accessing,executing, operating and m

aintaining reusable services w

ith appropriate quality of services and conforming w

ithall other requirem

ents, e.g. Security, privacy...)

Privacy

(All services necessary to guaranty privacy

Over m

edical data storage, access and S

haring. Privacy related services m

ust conform

with ethical E

U/N

ational regulations)

Layered View & Concepts

Generic to ALL domains(can theoretically be fully reused)

Generic to Medical domain(can theoretically be reused in other medical applications)

Specific to Project(can theoretically be partly reused since

abstracted from underlying IT)

Common PurposeInterfaces

Highly SpecializedInterfaces

System Architecture (2/2)

Mammogrid+A Grid-powered Mammography Database

Healthgrid (1)

Oncology•Breast Cancer (micro-calcifications and masses)

Hea

lthgr

id

• Second Opinion• Cancer Screening• Education and Training• Reference Database / Repository

neuGRIDA Grid-based e-Infrastructure for Data Archiving and

Computing Intensive Applications in neurosciences

Healthgrid (2)

QuestionA Marker of Alzheimer’s progression?

Neurology•Degenerative diseases

Hea

lthgr

id

• Biomarkers Assessment• Biomarkers Authoring• Extension to Other Medical Areas• Reference Database & Infrastructure

Pharmaco-EpidemiologyMulti-centre Pharma Grid-based

Data Warehouse for Epidemiological Studies

Healthgrid (3)

Pharmacology Hea

lthgr

id

• Epidemiological Studies• Scalable Dataware House• Scalable Statistical Analysis

• Translational Research• Reference Database

Health-e-Child, An Healthgrid for Paediatrics

Healthgrid (4)

Cardiology•Tetralogy of Fallot (ToF)•Cardiomyopathy (HCM, DCM)

Rheumatology•Juvenile Idiopathic Arthritis (JIA)

NeuroOncology•Brain Tumors – Gliomas

Hea

lthgr

id

• Decision Support• Vertical Data Integration• Knowledge Discovery• Reference Database of Rare Conditions

SENTINELLE NetworkBreast and Colon Cancer Screening,

Surveillance Network

Healthgrid (5)

Hea

lthgr

id

• Breast Cancer Screening • Colon Cancer Screening• Surveillance, Alert and Monitoring Network

SPIDeRSuper Peta-scale Infrastructure for

Distributed e-health and biomedical Research

Healthgrid (6)

Hea

lthgr

id

Neurology

Epidemiology

Drug Development

http://spider.healthgrid.org

Silken Bags

Silk Collaborations

SPIDeR WebA Super Infrastructure of about

- 6000 CPUs, - 100TB, - 15 new dedicated sites

GOSHUWE

IGG

SIEMENS

ASPER

UOA

INRIALYNKEUS

UCL

EGFFGG

MAAT

Clinical Site

R&D Site

+

DISIINDRA

PRODEMA

CERN

KI

VUmc

CETA

CIEMAT HG

CFC

Infrastructure

+MAAT

NECKER

FBF

+

++

OPBG+

++

JHU

SIEMENS++

MAAT COL

+

Healthgrid

DSS Paediat. Cancer Alzheimer BiomarkerCADe Breast Cancer20062005 2008

UWE

Mam

mog

rid+

Hea

lth-e

-Chi

ld

neuG

RID

+++++

Healthgrid

Marketing Plan (1)

Marketing Plan (2)

Healthgrid

+++++

DSS Paediat. Cancer Alzheimer BiomarkerCADe Breast CancerA Network of Certified Partners

- Support in porting new applications to HGSP- Online & Offline education services- OnDemand infrastructure and data for application training

- Access to infrastructure facilities for promoting new products- Direct access to market (i.e. Network of Clinical Institutions)

- Certification process and official label for software- Possibility to sell online consultancy

- Education careers: technicial (presales, maintenance and support, and operation) and sales/marketing

A Network of Clinical Institutions- User Support

- Online & Offline Education Services (from HGSP and from Certified Partners)

- Access to a large network of excellence at minimal cost- Access to state-of-the-art software from Certified Partners- Provide data for enriching the infrastructure

Infrastructure- Teaming-up with Telco Operators (i.e. Telefonica)

- Sustainable platform and infrastructure- Strong position in the market and its big sales network (not only in Spain but worldwide)

- Opened infrastructure to Consultancy and Systems Integrator firms (i.e. Indra, Entel)

+

THANK YOU FOR YOUR ATTENTION!