MINERALS IODINE
Dr. Vijay Marakala, MBBS, MD.
Assistant professor BIOCHEMISTRY SIMS & RC
IODINE
SOURCE RDA METABOLISM
FUNCTION DEFICIENCY
IODINE - SOURCES
Sea foods
Egg
Dairy products
Iodized salt
Drinking water
Vegetables
IODINE - RDA
150 µg/da
y
IODINE - METABOLISMAbsorptio
n
Upper small
intestine
Transport
Binding loosely
to plasma protein
s
Storage
80% in thyroid gland
Excretion
2/3rd in urine
IODINE - FUNCTION
Required for the synthesis of thyroid
hormonesT4 and T3
IODINE DEFICIENCY - CAUSES
DIETARY DEFECIENCY• Goitre belt
GOITROGENS• Thiocyanates • Thiourea
IODINE DEFICIENCY - FEATURES
Goiter
IODINE DEFICIENCY
Potassium iodideTreatmen
t
MAGNESIUM
MAGNESIUM
Sources RDA Distribution
Functions Disorders
MAGNESIUM - SOURCES
Green leafy
vegetables
Cereals
Nuts
Sea foods
MAGNESIUM - RDA
300-400
mg/day
MAGNESIUM - DISTRIBUTION
Total body magnesium is 25gm
67% in
bone
32% in
cells
Extra cellular magnesium is 1%Plasma magnesium
1.8 – 2.5mg/dl
MAGNESIUM - FUNCTIONSActivator of
many enzymesMaintain normal
muscle and nerve functionNeeded for
healthy bones and teeth
MAGNESIUM - DISORDERS
Hypomagnesaemia
Hypermagnesaemia
HYPOMAGNESAEMIA
CAUSES
Malnutrition, alcoholism
Malabsorption
Renal tubular acidosis
Toxemia of pregnancy
Drugs - diuretics
HYPOMAGNESAEMIA-FEATURESMuscle
cramps and tetanyCardiac
arrhythmias
Ataxia, tremor
HYPERMAGNESAEMIACAUSES Chronic renal failure
Rhabdomyolysis FEATURES Muscle weakness
Hypotension