UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
1
University of Pécs Faculty of Pharmacy
PHARMACY Major
STUDY PROGRAM 2021/2022
Elective and Optional Subjects
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
2
Table of Contents
1st semester
OPF-AR1-T __ Art Therapy 1. Basics __________________________________________________________________________ 5
OPF-BBM-T __ Introduction to Biometrics ______________________________________________________________________ 7
OPF-BFM-T __ Problem Solving in Biometrics ___________________________________________________________________ 9
OPF-DME-T __ Cancer is Preventable! ________________________________________________________________________ 11
OPF-GEM-T __ GMO _____________________________________________________________________________________ 13
OPF-H1A-T __ Medical Hungarian 1A - Communication Skills _____________________________________________________ 15
OPF-H1B-T __ Medical Hungarian 1B - Language Points _________________________________________________________ 17
OPF-HCS-T __ If only I knew how to do it... How to study effectively at university? ____________________________________ 19
OPF-N77-T __ English Brush Up Course For Pharmacy Students ___________________________________________________ 21
OPF-NS1-T __ Nobel Prize Awarded Cell Biology I _____________________________________________________________ 23
OPF-OTT-T __ History of Medicine __________________________________________________________________________ 25
OPE-KP1-T __ Basics of Chemistry 1 _________________________________________________________________________ 27
OPE-N06-T __ Medical Terminology _________________________________________________________________________ 29
OPE-SKS-T __ Inorganic Chemistry Calculations _______________________________________________________________ 31
OPE-GOM-T _ Poisonous Mushrooms ________________________________________________________________________ 33
OPE-BFA-T __ Physical Basis of Biophysics ___________________________________________________________________ 35
OPE-HPR-T __ Health Promotion ____________________________________________________________________________ 37
OPE-SP1-T __ Pharmacy Biophysics Seminars 1 ________________________________________________________________ 39
2nd semester
OPF-AR2-T __ Art Therapy 2. Management of Psychosomatic Diseases ______________________________________________ 41
OPF-BMK-T _ Methods and Experiments in Molecular Biology ____________________________________________________ 43
OPF-ETF-T __ Preparation for the Physiology __________________________________________________________________ 45
OPF-FPB-T __ Biological Applications of Fluorescence Polarization Methods _________________________________________ 47
OPF-H2A-T __ Medical Hungarian 2A - Communication Skills _____________________________________________________ 50
OPF-H2B-T __ Medical Hungarian 2B - Language Points _________________________________________________________ 52
OPF-IZM-T __ Molecular Basis of Muscle Function _____________________________________________________________ 54
OPF-MGY-T _ Medicinal Plants in the Mecsek Mountain _________________________________________________________ 56
OPF-N04-T __ Anatomical Terminology ______________________________________________________________________ 58
OPF-NS2-T __ Nobel Prize Awarded Cell Biology II _____________________________________________________________ 60
OPF-PLH-T __ The Placebo Effect ___________________________________________________________________________ 62
OPF-VEO-T __ Vaccination, Anti-Vaccination Movements: Do More Harm than Good __________________________________ 64
OPF-XC1-T __ Extracellular Vesicles: Basics, Isolation and Application Methods 1 _____________________________________ 65
OPE-ABI-T __ Applied Biometrics ___________________________________________________________________________ 68
OPE-FKS-T __ Physical Chemistry Problem Solving Seminar ______________________________________________________ 70
OPE-KP2-T __ Basics of Chemistry 2 _________________________________________________________________________ 72
OPE-QAS-T __ Quantitative Analytical Chemistry Calculation _____________________________________________________ 74
OPE-DRD-T __ Drug Design ________________________________________________________________________________ 76
OPE-ETI-T ___ Pharmacy Ethics _____________________________________________________________________________ 78
OPE-GKT-T __ History of Manufacture of Medicines _____________________________________________________________ 80
OPE-BES-T __ Bioethics Seminar ____________________________________________________________________________ 82
OPE-JEA-T __ Diseases of Signal Transduction _________________________________________________________________ 84
OPE-SP2-T __ Pharmacy Biophysics Seminars 2 ________________________________________________________________ 86
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
3
3rd semester
OPF-CY1-T __ Cybernetics for Medical, Dentistry and Pharmacy Students 1 __________________________________________ 88
OPF-EBK-T __ Food Safety and Crisis Situations ________________________________________________________________ 90
OPF-H3A-T __ Medical Hungarian 3A - Basics of Medical Communication for Students of Pharmacy ______________________ 92
OPF-H3B-T __ Medical Hungarian 3B - Medical Communication in Practice for Students of Pharmacy _____________________ 94
OPF-HB1-T __ How to Achieve Better Grade in Organic Chemistry 1 _______________________________________________ 96
OPF-IPM-T __ Innovation and Project Management from a Business Perspective (KÜLÖN KURZUS!!!) ___________________ 98
OPF-MGE-T __ Molecular Gerontology_______________________________________________________________________ 100
OPF-SNA-T __ Carbon Nanostructures _______________________________________________________________________ 102
OPF-SSG-T __ Histology Seminar for Pharmacy Students ________________________________________________________ 104
OPF-TG1-T __ Student Project Research for Students of Pharmaceutist Programme 1 __________________________________ 106
OPF-TMB-T __ Molecular Biology of Tumors _________________________________________________________________ 107
OPE-DM1-T __ Demonstrator Activity 1 ______________________________________________________________________ 109
OPE-WMI-T __ Weak Molecular Interactions __________________________________________________________________ 110
OPE-TSS-T __ Medical Applications of Mass Spectrometry ______________________________________________________ 113
OPE-BEE-T __ Basics of Epidemiology ______________________________________________________________________ 115
OPE-EHS-T __ Hunger, Satiety and Disturbances of Body Weight Regulation ________________________________________ 117
OPE-HL1-T __ Advanced physiology 1 ______________________________________________________________________ 119
4th semester
OPF-CME-T __ Computational Molecular Engineering ___________________________________________________________ 121
OPF-CY2-T __ Cybernetics for Medical, Dentistry and Pharmacy Students 2 _________________________________________ 123
OPF-CSU-T __ Miracles of Living Materials ("Realistic" Biochemistry) _____________________________________________ 125
OPF-DR2-T __ Drug Design 2 _____________________________________________________________________________ 127
OPF-ESP-T __ Exercise and Sport Physiology _________________________________________________________________ 129
OPF-GMI-T __ Daily Routine and Challenges in Various Fields of the Pharmacy Profession _____________________________ 131
OPF-H4A-T __ Medical Hungarian 4A - Basics of Medical Communication for Students of Pharmacy _____________________ 133
OPF-H4B-T __ Medical Hungarian 4B - Medical Communication in Practice for Students of Pharmacy ____________________ 135
OPF-HB2-T __ How to Achieve Better Grade in Organic Chemistry 2 ______________________________________________ 137
OPF-HFG-T __ Great Discoveries in Pharmacology _____________________________________________________________ 139
OPF-QBI-T __ Quantum Biology: Quantum Phenomena in Biological Processes ______________________________________ 141
OPF-SKI-T ___ Basics of Chemical Informatics ________________________________________________________________ 144
OPF-TG2-T __ Student Project Research for Students of Pharmaceutist Programme 2 __________________________________ 146
OPF-VAN-T __ Iron Metabolism: from Molecular Mechanisms to Clinical Consequences _______________________________ 147
OPE-BKM-T _ Basic Methods of Scientific Research ___________________________________________________________ 149
OPE-DM2-T __ Demonstrator Activity 2 ______________________________________________________________________ 152
OPE-GMO-T _ Modelling the Structure and Interactions of Bioactive Molecules ______________________________________ 153
OPE-SME-T __ Spectrometric Identification of Organic Compounds ________________________________________________ 156
OPE-HL2-T __ Advanced Physiology 2 ______________________________________________________________________ 158
OPE-TIZ-T ___ Central Regulation of Feeding and Metabolism. New Approaches _____________________________________ 160
5th semester
ATT5-T _____ Physical Education 5 ________________________________________________________________________ 162
OPF-GKG-T __ Gas Chromatography ________________________________________________________________________ 163
OPF-GLK-T __ Bioinorganic Chemistry for Pharmacy Students ____________________________________________________ 165
OPF-GMT-T __ Drug Metabolism and Drug Toxicity ____________________________________________________________ 167
OPF-HKG-T __ Interfacial Chemistry in Pharmaceutical Technology ________________________________________________ 169
OPF-HVS-T __ Synthesis of Heterocyclic Compounds and Their Application in Therapy ________________________________ 171
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
4
OPF-MEM-T _ Health Benefits of Honey and Other Bee Products __________________________________________________ 174
OPF-TS1-T __ Calculations in Pharmaceutical Technology 1 _____________________________________________________ 176
OPF-VGG-T __ Collecting and Conservation of Wild Native Medicinal Plants ________________________________________ 178
OPE-EFA-T __ Ethnopharmacobotany _______________________________________________________________________ 180
OPE-FAO-T __ Applied Health Economics ____________________________________________________________________ 182
OPE-TG3-T __ Student Project Research for Students of Pharmaceutist Programme 3 __________________________________ 184
OPE-DM3-T __ Demonstrator Activity 3 ______________________________________________________________________ 185
6th semester
OPF-DTS-T __ The Role of Drug Transporters _________________________________________________________________ 186
OPF-NSG-T __ Plant Products in the Pharmaceutical Practice _____________________________________________________ 189
OPF-TS2-T __ Calculations in Pharmaceutical Technology 2 _____________________________________________________ 191
OPE-STK-T __ Basics of Stereochemistry ____________________________________________________________________ 193
OPE-GFK-T __ Physico-Chemical Bases of Drug Action _________________________________________________________ 195
OPE-TG4-T __ Student Project Research for Students of Pharmaceutist Programme 4 __________________________________ 197
OPE-VFM-T __ Business Development and Management _________________________________________________________ 198
OPE-ASZ-T __ The Antimicrobial Drugs and their Clinical Use ___________________________________________________ 200
OPE-DM4-T __ Demonstrator Activity 4 ______________________________________________________________________ 202
OPE-KPR-T __ Chemoprevention ___________________________________________________________________________ 203
7th semester
OPF-FEA-T __ Basics of Infectious Disease Epidemiology _______________________________________________________ 205
OPF-KIA-T __ Essential Oils and Clinical Aromatherapy ________________________________________________________ 207
OPE-FMA-T __ Data Analysis 1 ____________________________________________________________________________ 209
OPE-FM2-T __ Data Analysis 2 ____________________________________________________________________________ 211
OPE-DM5-T __ Demonstrator Activity 5 ______________________________________________________________________ 213
OPE-OPM-T __ Online Pharmaceutical Market and the Dangers of Counterfeit Medicines _______________________________ 214
OPE-SHK-T __ Design and Industrial Manufacture of Medicines ___________________________________________________ 216
8th semester
OPF-GTH-T __ Gene Therapy ______________________________________________________________________________ 218
OPE-DM6-T __ Demonstrator Activity 6 ______________________________________________________________________ 220
OPE-DRO-T __ Drug and Substance Abuse ____________________________________________________________________ 221
OPE-FAJ-T __ Pain and Analgesics _________________________________________________________________________ 223
OPE-MGT-T _ Pharmaceutical Technology of Modified Drug Release ______________________________________________ 225
OPE-IVF-T __ Infections and Immunity ______________________________________________________________________ 227
9th semester
OPF-SUO-T __ Emergency Medicine ________________________________________________________________________ 229
OPE-DM7-T __ Demonstrator Activity 7 ______________________________________________________________________ 231
OPE-GST-T __ Special Fields of Pharmacology ________________________________________________________________ 232
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
5
OPF-AR1-T ART THERAPY 1. BASICS
Course director: DR. TAMÁS OLLMANN, assistant professor
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 6 lectures + 0 practices + 6 seminars = total of 12 hours
Course headcount limitations (min.-max.): 3 – 50 Prerequisites: -
Topic
Art therapy is based on the idea that the traumatic experience may not be accessible verbally but instead is locked in a subconscious
form. Metaphoric cues employed in art methods allow the delicate, ecological transformation of unpleasant experience into conscious
knowledge, and turn the emotional or physical pain into a resource. Basic knowledge of art-therapeutical methods will replenish the
repertoire of the students with multiple techniques for assistance (to self and others) in critical situations, including state of disease, with
the use of creative tools. The course contributes to a better understanding of the psychological aspects of diseases, their causes,
management, and prevention. Improvement of awareness in relationships and lifestyle, work with self-esteem, development of creative
thinking and problem solving, training of focusing, generalization, and isolation of the main ideas, improvement of verbal and fine motor
skills,- are the few additional assets of the course which might be beneficial for the future physicians. The methods are designed for
persons with ordinary creative skills, thus do not require special equipment or abilities. Students can expect informative and well-
structured lectures followed by dynamic, interactive seminar classes. Topics of the first semester cover the basic principles and the main
branches of art therapy.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Completed practical tasks, written test.
Making up for missed classes
Presentation on topic.
Reading material
- Obligatory literature
- Literature developed by the Department
The slides will be available.
- Notes
- Recommended literature
Lectures
1 Introduction to art therapy (AT). Basic terms, functions, principles of AT.
Zagorácz Olga
2 Plastic materials in AT.
Zagorácz Olga
3 Texts and associative cards in AT.
Zagorácz Olga
4 Phototherapy and collaging in AT.
Zagorácz Olga
5 Textile-therapy, the essence of ancient and innovative techniques.
Zagorácz Olga
6 Innovative methods of AT.
Zagorácz Olga
Practices
Seminars
1 Fine art as AT instrument.
Zagorácz Olga
2 Plasticine, dough, clay as AT instruments.
Zagorácz Olga
3 Storytelling, writing in AT.
Zagorácz Olga
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
6
4 Practices with images in AT.
Zagorácz Olga
5 Practices with textile, creation of dolls.
Zagorácz Olga
6 Art-coaching.
Zagorácz Olga
Exam topics/questions
The topics of the lectures.
Participants
Zagorácz Olga (J5ZJ9T)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
7
OPF-BBM-T INTRODUCTION TO BIOMETRICS
Course director: DR. LÁSZLÓ PÓTÓ, associate professor
Institute of Bioanalysis [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 12 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 20 Prerequisites: -
Topic
Exploring data (using graphs and numbers) are usually handled as one-lesson / first chapter by basic statistical courses. This is, because
a first course in statistics introduces many new skills. It also introduces some new ideas, that all are hard to understand for students. The
new approach is to make a solid foundation to learn statistics by a more thorough introduction to those: The course tries to make clear a
few of these fundamental ideas of statistics - limited to understanding and working with data. An improved skill for exploring data is
useful not only at your classes and your future job but in the everyday life as well.
Conditions for acceptance of the semester
Maximum one missed class.
Mid-term exams
Active participation at the classes.
Making up for missed classes
One extra class
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
László Pótó: Biometrics, workbook, Pécs, 2020
- Recommended literature
1, Moore, D. S.: The Basic Practice of Statistics, 7th edition, 2015
2, Moore, David S., McCabe, George P.: Introduction to the Practice of Statistics, 5th edition, W.H. Freeman, 2005 and
Yates, Dan, Moore, David S., Starnes, Daren S.: The Practice of Statistics (TI-83/89 Graphing Calculator Enhanced) 2/e, W.H.
Freeman, 2003 or
3, Rees, W. G.: Essential Statistics, Chapman and Hall, 1992
Lectures
Practices
1 Probability examples 1
Dr. Pótó László
2 Probability examples 1
Dr. Pótó László
3 Probability examples 2 - discrete distributions
Dr. Pótó László
4 Probability examples 2 - discrete distributions
Dr. Pótó László
5 Exploring data by graphs
Dr. Pótó László
6 Exploring data by graphs
Dr. Pótó László
7 Exploring data by numbers - sample measures
Dr. Pótó László
8 Exploring data by numbers - sample measures
Dr. Pótó László
9 The normal distribution
Dr. Pótó László
10 The normal distribution
Dr. Pótó László
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
8
11 Distribution of the mean; Stat estimation: the CI for the expected value
Dr. Pótó László
12 Distribution of the mean; Stat estimation: the CI for the expected value
Dr. Pótó László
Seminars
Exam topics/questions
No exam - but active participation on the classes is a must.
Participants
Dr. Pótó László (FIO4UU)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
9
OPF-BFM-T PROBLEM SOLVING IN BIOMETRICS
Course director: DR. LÁSZLÓ PÓTÓ, associate professor
Institute of Bioanalysis [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 12 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 20 Prerequisites: -
Topic
Give a chance to have more practice to solve problems in Biometrics using PC and the SPSS software in the computer room. This was a
regular need of the students earlier since the special way how a MD should handle the typical medical problems (special way of thinking)
was not founded by the secondary school education. This foundation is an important focus point of the Biometrics course. It seems, the
weekly 1+1 lectures were not enough for most of the students for completing this important goal: To develop some brand new skills.
This course offers an organized way for that extra practices. It offers also some ‘brushing up’ chances for those who has completed
Biometrics earlier.
Conditions for acceptance of the semester
Maximum one missed class
Mid-term exams
Active participation on the classes.
Making up for missed classes
One extra class
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
László Pótó: Biometrics, workbook, Pécs, 2020.
- Recommended literature
1, Moore, D. S.: The Basic Practice of Statistics, 7th edition, 2015. or
2, Moore, David S., McCabe, George P.: Introduction to the Practice of Statistics, 5th edition, W.H. Freeman, 2005 and
Yates, Dan, Moore, David S., Starnes, Daren S.: The Practice of Statistics (TI-83/89 Graphing Calculator Enhanced) 2/e, W.H.
Freeman, 2003 or
3, Rees, W. G.: Essential Statistics, Chapman and Hall, 1992
Lectures
Practices
1 The one sample (and the paired samples) t test
Dr. Pótó László
2 The one sample (and the paired samples) t test
Dr. Pótó László
3 The CI and the hypothesis testing - the type one and type two errors.
Dr. Pótó László
4 The CI and the hypothesis testing - the type one and type two errors. MDM basics 1.
Dr. Pótó László
5 The independent samples t test
Dr. Pótó László
6 The independent samples t test
Dr. Pótó László
7 The linear regression
Dr. Pótó László
8 The linear regression
Dr. Pótó László
9 The contingency tables - the chi squares test
Dr. Pótó László
10 The contingency tables - the chi squares test. MDM-1/2
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
10
Dr. Pótó László
11 The nonparametric tests
Dr. Pótó László
12 The nonparametric tests. MDM basics 2.
Dr. Pótó László
Seminars
Exam topics/questions
No exam but active participation on the classes is a must.
Participants
Dr. Pótó László (FIO4UU)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
11
OPF-DME-T CANCER IS PREVENTABLE!
Course director: DR. ISTVÁN ZOLTÁN KISS, professor
Department of Public Health Medicine [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 22 lectures + 2 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 30 Prerequisites: -
Topic
One of the major challenges for the health care system of the 21st century is the high number of cancer caused deaths. Over the past
decades, despite a significant development on the field of medicine, the prognosis of this disease is still not satisfactory. Thus prevention
has a key role in in the fight against cancer. The course gives a description on the different types of cancer their major risk factors for a
more detailed understanding. Methods of cancer prevention will be described and emphasized - including theoretical knowledge and a
practical guide as well. During the course the results of most recent human epidemiological studies on cancer will also be described.
Conditions for acceptance of the semester
Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 4x45 min. Otherwise signature of
grade book is denied.
Mid-term exams
Making up for missed classes
There are no make-up classes.
Reading material
- Obligatory literature
- Literature developed by the Department
Educational material uploaded on Neptun.
- Notes
- Recommended literature
Robert Weinberg (ed.): The Biology of Cancer, Garland Science 2006 ISBN 0815340788
Boffetta P., La Veccia: Neoplasms 2009. In Detels R, Beaglehole R, Lansang MA and Gulliford M (eds.) Oxford Textbook of Public
Health, 5th ed., Oxfort University Press
Lectures
1 Cancer in the 21st century
Dr. Kiss István Zoltán
2 Cancer in developing and developed countries
Dr. Kiss István Zoltán
3 The process of carcinogenesis I.
Dr. Kiss István Zoltán
4 The process of carcinogenesis II.
Dr. Kiss István Zoltán
5 Characteristics of cancer cells
Dr. Kiss István Zoltán
6 Molecular epidemiology of cancer
Dr. Kiss István Zoltán
7 The most important cancer risk factors in general I.
Dr. Kiss István Zoltán
8 The most important cancer risk factors in general II.
Dr. Kiss István Zoltán
9 Lung cancer
Dr. Kiss István Zoltán
10 Colorectal tumors I.
Dr. Kiss István Zoltán
11 Colorectal tumors II.
Dr. Kiss István Zoltán
12 Breast cancer
Dr. Kiss István Zoltán
13 Prostate cancer
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
12
Dr. Kiss István Zoltán
14 Head and neck cancer
Dr. Kiss István Zoltán
15 Pancreatic cancer
Dr. Kiss István Zoltán
16 Gastric cancer
Dr. Kiss István Zoltán
17 Liver cancer
Dr. Kiss István Zoltán
18 Cervical cancer
Dr. Kiss István Zoltán
19 Ovarian cancer
Dr. Kiss István Zoltán
20 Skin cancer
Dr. Kiss István Zoltán
21 Leukemia
Dr. Kiss István Zoltán
22 Less frequent tumors
Dr. Kiss István Zoltán
Practices
1 Genetics, genomics and epigenetics in cancer prevention
Dr. Kiss István Zoltán
2 Cancer prevention - Recommendations
Dr. Kiss István Zoltán
Seminars
Exam topics/questions
Neptun
Participants
Dr. Kiss István Zoltán (EFZCGE)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
13
OPF-GEM-T GMO
Course director: DR. ZOLTÁN GYÖNGYI, senior research fellow
Department of Public Health Medicine [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 1
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 30 Prerequisites: -
Topic
The application of genetically modified organisms (GMOs) gains more and more ground in food industry. Over the direct health effect,
they have an impact on human economy, health and environment. The topic provokes social debate, in which, in lack of information,
delusions also appear. The tecnology is also used in industry, science and human therapy. During the education, students receive a
knowledge of molecular background of production GMOs, their possible health risks, their occurrence in foodstuffs, medical applications,
detection, regulations, authorization, economical and social impacts.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Providing a new date after individual consultation.
Making up for missed classes
none
Reading material
- Obligatory literature
- Literature developed by the Department
Slides on the Neptun
- Notes
- Recommended literature
Lectures
1 Definition of GMO
Dr. Gyöngyi Zoltán
2 Needs of GMOs in different disciplines
Dr. Gyöngyi Zoltán
3 The development of agriculture to GMOs
Dr. Gyöngyi Zoltán
4 The role of GMOs in crop production
Dr. Gyöngyi Zoltán
5 The role of GMOs in animal breeding
Dr. Gyöngyi Zoltán
6 Impact of GM crops on natural habitats and organic farming
Dr. Gyöngyi Zoltán
7 GMO production. History of science
Dr. Gyöngyi Zoltán
8 GMO production. Description of biotechnology methods
Dr. Gyöngyi Zoltán
9 GMO detection methods
Dr. Gyöngyi Zoltán
10 Occurrence of GM organisms in food, their detectability
Dr. Gyöngyi Zoltán
11 GMO in industry
Dr. Gyöngyi Zoltán
12 GMO in the pharmaceutical industry
Dr. Gyöngyi Zoltán
13 GMO in science
Dr. Gyöngyi Zoltán
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
14
14 GMO and disease prevention
Dr. Gyöngyi Zoltán
15 GMO and therapy
Dr. Gyöngyi Zoltán
16 The past, present and future of gene therapy
Dr. Gyöngyi Zoltán
17 Genetic modification of humans
Dr. Gyöngyi Zoltán
18 Potential health effects of GMOs
Dr. Gyöngyi Zoltán
19 Background of deaths caused by GMOs
Dr. Gyöngyi Zoltán
20 Preventing the harmful effects of GMOs
Dr. Gyöngyi Zoltán
21 Authorization procedures of GMOs
Dr. Gyöngyi Zoltán
22 GMO production for commercial use
Dr. Gyöngyi Zoltán
23 The economic impact of GMOs
Dr. Gyöngyi Zoltán
24 Social debates, publicity
Dr. Gyöngyi Zoltán
Practices
Seminars
Exam topics/questions
A GMO fogalma
A GMO megjelenésének igénye különböző tudományterületeken
A mezőgazdaság fejlődése a GMO megjelenéséig
A GM szervezetek szerepe a növénytermesztésben
A GM szervezetek szerepe az állattenyésztésben
A GM növények hatása természetes élőhelyekre és a biogazdálkodásra
GMO előállítás. Tudománytörténeti áttekintés
GMO előállítás. Biotechnológiai módszerek ismertetése
GMO kimutatási módszerek
A GM szervezetek élelmiszerekben való előfordulása, kimutathatóságuk
GMO az iparban
GMO a gyógyszeriparban
GMO a tudományban
GMO és a betegségmegelőzés
GMO és a gyógyítás
A génterápia múltja, jelene és jövője
Az ember genetikai módosítása
A GM szervezetek lehetséges egészségkárosító hatásai
GM szervezetek okozta halálesetek háttere
A GM szervezetek egészségkárosító hatásának kivédése
A GM szervezetek engedélyezésének feltételei
Kereskedelmi GMO előállítás
A GM szervezetek gazdasági hatása
Társadalmi viták, tájékoztatás
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
15
OPF-H1A-T MEDICAL HUNGARIAN 1A - COMMUNICATION SKILLS
Course director: DR. VILMOS WARTA, associate professor
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OPF-H1B-T parallel
Topic
To establish basic skills in reading, writing, listening and speaking Hungarian in preparation for effective medical communication.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Written midterm and end of the term tests are compulsory. Other short written tests to be discussed with the course tutor in each individual
case. Several oral tests are taken, dates are to be discussed with the course tutor. Make up tests possible only during the semester classes.
Making up for missed classes
Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In
the case of absences up to 25% of total class time, oral examination will have to be taken
Reading material
- Obligatory literature
Anamnézis magyarul (Magyar orvosi szaknyelv kezdőknek) by Renáta Halász, 2015. Pécs
- Literature developed by the Department
In-house course book: at the homepage of the institute:
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
- Notes
In-house course book: at the homepage of the institute:
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
- Recommended literature
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
Lectures
Practices
Seminars
1 Greeting people, formality and informality
2 Greeting people, formality and informality
3 Addressing people, men and women
4 Addressing people, men and women
5 Starting conversation, the elderly and children
6 Starting conversation, the elderly and children
7 Introducing, equal and unequal relations
8 Introducing, equal and unequal relations
9 Nutritional History Taking
10 Nutrients
11 Nutrients
12 Test 1
13 Health Preservation, Sports, Addictions
14 Writing CV, occupation, work
15 Medical Specialties, Consulting Room and Ward
16 Telling CV, family relations
17 Introducing family
18 Introducing family
19 Describing people - Internal and external features
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16
20 Describing people - Internal and external features
21 Health care institutions, consolidation
22 Test 2
23 Evaluation
24 Evaluation
Exam topics/questions
Two written test papers and oral presentation topics to be discussed with the course tutor in each individual case.
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Nagy Renáta (JR0PVR), Ronczykné Berta Anikó (CJZOFU), Szalai-
Szolcsányi Judit (RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
17
OPF-H1B-T MEDICAL HUNGARIAN 1B - LANGUAGE POINTS
Course director: DR. VILMOS WARTA, associate professor
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OPF-H1A-T parallel
Topic
Familiarizing foreign students with basic paradigms used in specific conversations.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Written midterm and end of the term tests are compulsory. Other short written tests to be discussed with the course tutor in each individual
case. Several oral tests are taken, dates are to be discussed with the course tutor. Make up tests possible only during the semester classes.
Making up for missed classes
Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In
the case of absences up to 25% of total class time, oral examination will have to be taken
Reading material
- Obligatory literature
Anamnézis magyarul (Magyar orvosi szaknyelv kezdőknek) by Renáta Halász, 2015. Pécs
- Literature developed by the Department
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
- Notes
In-house course book: at the homepage of the institute:
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
- Recommended literature
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
Lectures
Practices
Seminars
1 Basics of Hungarian Phonetics and Morphology
2 Basics of Hungarian Phonetics and Morphology
3 Personal Pronouns - formal and informal style
4 Personal Pronouns - formal and informal style
5 Constructing Questions - Question Words
6 Constructing Questions - Question Words
7 Numerals - Cardinal, Ordinal, Labels
8 Numerals - Cardinal, Ordinal, Labels
9 Verbs - Definite and Indefinite Conjugation
10 Verbs - Definite and Indefinite Conjugation
11 Expressing Frequency
12 Expressing Frequency
13 Test 1
14 Articles
15 Modality - necessity
16 Modality - necessity
17 Objective Case
18 Verbal prefixes
19 Expressing Time
20 Expressing Time
21 Expressing Location - Trinity of Directions
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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18
22 Dative Case
23 Test 2
24 Course Evaluation
Exam topics/questions
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Nagy Renáta (JR0PVR), Ronczykné Berta Anikó (CJZOFU), Szalai-
Szolcsányi Judit (RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
19
OPF-HCS-T IF ONLY I KNEW HOW TO DO IT... HOW TO STUDY EFFECTIVELY AT UNIVERSITY?
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 20 Prerequisites: -
Topic
The course introduces students to study techniques and approaches that can be used effectively in studying any subject and passing exams
at the university. Classes will include developing study skills and attitudes through interactive tasks to enhance focusing, reading,
comprehension, grasping the main points, memorizing and logical thinking. Students will analyze their own studying customs and
strategies, and will be guided through changing these habits if necessary, in order to study more effectively and willingly. After providing
some theoretical background in the lectures, students can put into practice each technique in the seminars.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Mastering the theoretical background and implementing the course material into practice will be checked by individual tasks and team
work during classes, as well as home assignments.
Making up for missed classes
Students can make up for missed classes by completing assignments at home or by presenting a topic related to the course.
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture materials and seminar handouts will be available in Neptun Meet Street.
- Notes
- Recommended literature
Marty Lobdell (2015): Study Less, Study Smart.
Lectures
1 General characteristics of university studies. Types of classes, assignments, exams.
Dr. Farkas Ágnes
2 Know yourself: motivation to study
Dr. Farkas Ágnes
3 Know yourself: styles of studying
Dr. Farkas Ágnes
4 Know yourself: strategies of studying
Dr. Farkas Ágnes
5 Study techniques: reading
Dr. Farkas Ágnes
6 Study techniques: studying from a textbook
Dr. Farkas Ágnes
7 Study techniques: taking notes, preparing an outline
Dr. Farkas Ágnes
8 Study sources: using a library
Dr. Farkas Ágnes
9 Study sources: using the internet
Dr. Farkas Ágnes
10 Test writing, question types
Dr. Farkas Ágnes
11 Preparing for exams, passing an exam
Dr. Farkas Ágnes
12 Presentations
Dr. Farkas Ágnes
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20
13 Manage your study customs: optimal outer and inner conditions
Dr. Farkas Ágnes
14 Manage your study customs: time management
Dr. Farkas Ágnes
Practices
Seminars
1 Motivation inventory
Pap Ramóna
2 Diagnosis of style of studying
Pap Ramóna
3 Reading comprehension practices
Pap Ramóna
4 Practices for focusing your attention
Pap Ramóna
5 Image memories - memory images
Pap Ramóna
6 Concentration practices
Pap Ramóna
7 Problem solving tasks
Pap Ramóna
8 Logical tasks developing combinatory skills
Pap Ramóna
9 Developing peripheral vision
Pap Ramóna
10 Increasing the width of visual fixation
Pap Ramóna
11 Rhythmic eye movements
Pap Ramóna
12 Practice to observe and increase awareness of study customs
Pap Ramóna
13 Implementing new study customs
Pap Ramóna
14 Summarizing experiences, feedback
Pap Ramóna
Exam topics/questions
1. General characteristics of university studies. Types of classes, assignments, exams.
2. Know yourself: motivation to study
3. Know yourself: styles of studying
4. Know yourself: strategies of studying
5. Study techniques: reading
6. Study techniques: studying from a textbook
7. Study techniques: taking notes, preparing an outline
8. Study sources: using a library
9. Study sources: using the internet
10. Test writing, question types
11. Preparing for exams, passing an exam
12. Presentations
13. Manage your study customs: optimal outer and inner conditions
14. Manage your study customs: time management
Participants
Pap Ramóna (OGEM0W)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
21
OPF-N77-T ENGLISH BRUSH UP COURSE FOR PHARMACY STUDENTS
Course director: DR. VILMOS WARTA, associate professor
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 15 Prerequisites: -
Topic
The Faculty of Pharmacy and the Department of Languages for Biomedical Purposes and Communication provides an opportunity for
pharmacy students to brush up their Academic English written and oral skills in 24 contact hours.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Two written test papers:
Week 6: Test 1; Week 12: Test 2.
Making up for missed classes
To be discussed with the course tutor.
Reading material
- Obligatory literature
- Literature developed by the Department
In-house materials
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Review of verb tenses
Dr. Warta Vilmos
2 Review of verb tenses
Dr. Warta Vilmos
3 Review of verb tenses
Dr. Warta Vilmos
4 Review of verb tenses
Dr. Warta Vilmos
5 Review of verb tenses
Dr. Warta Vilmos
6 Review of verb tenses
Dr. Warta Vilmos
7 Impersonalisation
Dr. Warta Vilmos
8 Impersonalisation
Dr. Warta Vilmos
9 Impersonalisation
Dr. Warta Vilmos
10 Impersonalisation
Dr. Warta Vilmos
11 Written Test 1
Dr. Warta Vilmos
12 Written Test 1
Dr. Warta Vilmos
13 Modality and politeness strategies
Dr. Warta Vilmos
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22
14 Modality and politeness strategies
Dr. Warta Vilmos
15 Modality and politeness strategies
Dr. Warta Vilmos
16 Modality and politeness strategies
Dr. Warta Vilmos
17 Modality and politeness strategies
Dr. Warta Vilmos
18 Modality and politeness strategies
Dr. Warta Vilmos
19 Nominalisation
Dr. Warta Vilmos
20 Nominalisation
Dr. Warta Vilmos
21 Nominalisation
Dr. Warta Vilmos
22 Nominalisation
Dr. Warta Vilmos
23 Written Test 2
Dr. Warta Vilmos
24 Written Test 2
Dr. Warta Vilmos
Exam topics/questions
Participants
Dr. Németh Tímea (X8VRGN), Dr. Warta Vilmos (SJYRAV), Nagy Renáta (JR0PVR), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
23
OPF-NS1-T NOBEL PRIZE AWARDED CELL BIOLOGY I
Course director: DR. MARIANNA PAP, associate professor
Department of Medical Biology and Central Electron Microscope Laboratory [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 200 Prerequisites: -
Topic
The aim of the course is to present the most important and most exciting Nobel Prize-winning molecular cell biology discoveries based
on Nobel lectures given by the winners. The background story of the awards reveals many years of research work, good ideas, good
fortune mixed with family and other personal memories. There is no single recipe for success, the road is always a bit different, and
perhaps the only common feature is the teamwork. From the presentations one might get insight of the winners” personality as well. An
important aspect was in the selection of the topics to emphasize their significance (DNA-, RNA-structure and their synthesis, ribosome
function), their impact on current medical way of thinking (e.g. Prions) and diagnostic methods (e.g. recombinant DNA technology,
DNA sequencing), the description of their present and future medical applicability (e.g. in vitro fertilization), as well as to highlight their
potential relations to different diseases (e.g. cell cycle regulation, reprogram of differentiated cells, RNA interference, papillomaviruses,
HIV). Lectures are organized based on the topics related to the weekly schedule of the molecular cell biology course, not in chronological
order. Most of the presented discoveries and experiments are involved in the molecular cell biology course material, so hopefully their
discussion helps in the better understanding of those topics and lead to a more effective and shorter exam preparation.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
2 written tests: on week 7 and on week 14.
Making up for missed classes
Participation on Hungarian or German lectures is the only possibility to make-up missed lectures.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
www.nobelprize.org
Lectures
1 Life of Alfred Nobel
Dr. Pap Marianna
2 History of Nobel prize, interesting facts
Dr. Pap Marianna
3 Structure of proteins
Dr. Pap Marianna
4 Prions
Dr. Pap Marianna
5 Structure of nucleic acids, catalytic RNA molecules
Dr. Pap Marianna
6 Recombinant DNA technology
Dr. Pap Marianna
7 PCR
Dr. Pap Marianna
8 DNA sequencing
Dr. Pap Marianna
9 Inhibition of gene expression (KO mutation)
Dr. Pap Marianna
10 Inhibition of gene expression (RNA interference)
Dr. Pap Marianna
11 Regulation of cell cycle
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
24
Dr. Pap Marianna
12 Regulation of cell cycle
Dr. Pap Marianna
13 DNA replication
Dr. Pap Marianna
14 DNA repair
Dr. Pap Marianna
15 Eukaryotic RNA synthesis
Dr. Pap Marianna
16 Splicing
Dr. Pap Marianna
17 Structure and function of ribosomes
Dr. Pap Marianna
18 Role of RNA molecules in translation, Genetic code
Dr. Pap Marianna
19 Gene regulation in prokaryotic cells
Dr. Pap Marianna
20 Gene regulation in eukaryotic cells
Dr. Pap Marianna
21 Rough endoplasmic reticulum, vesicular transport
Dr. Pap Marianna
22 Receptor-mediated endocytosis
Dr. Pap Marianna
23 Exam
Dr. Pap Marianna
24 Exam
Dr. Pap Marianna
Practices
Seminars
Exam topics/questions
.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
25
OPF-OTT-T HISTORY OF MEDICINE
Course director: DR. TAMÁS MOLNÁR F., professor
Department of Operational Medicine [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 1
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 80 Prerequisites: -
Topic
The purpose of the course is to give an opportunity for reviewing the progress in medicine historically, from the ancient times up to the
present époque, on the basis of cultural background. The understanding of the fact that contemporary medicine is the result of the efforts
of several centuries will be hopefully stimulatory for the students in the professional improvement, realizing that both the theoretical
basis and healing practice are due to the devoted work of previous generations. Accordingly, the progress from healing art to healing
science will be illustrated in relation to the culture of previous centuries.
Conditions for acceptance of the semester
Survey of the theoretical basis of medical practice in a historical period.
Mid-term exams
Making up for missed classes
Reading material
- Obligatory literature
- Literature developed by the Department
Summary of the content of each lecture (detailed description of authors and the main outlines of their activity promoting the medicine)
- Notes
- Recommended literature
Delano: The Story of Medicine, London
Benke J.: Az orvostudomány története - Hungarian ed. with English summary, Medicina, Bp. 2008.
Lectures
1 History of Medicine – WHY?
Dr. Molnár F. Tamás
2 History of Medicine – WHY?
Dr. Molnár F. Tamás
3 Structure of lectures – groups
Dr. Molnár F. Tamás
4 Structure of lectures – groups
Dr. Molnár F. Tamás
5 Ancient - Stone Age / Egypt- India
Dr. Molnár F. Tamás
6 Ancient - Greeks - Hyppocrates
Dr. Molnár F. Tamás
7 Ancient - Romans - Galenus
Dr. Molnár F. Tamás
8 Ancient - Mythology and diseases
Dr. Molnár F. Tamás
9 Middle age - Cloisters and Monks
Dr. Molnár F. Tamás
10 Middle age - Arabs – India / China / America
Dr. Molnár F. Tamás
11 Middle age - Surgeons & Medications
Dr. Molnár F. Tamás
12 Middle age - Renessaince: anatomy and medicine
Dr. Molnár F. Tamás
13 Middle age - Enlightement: Science and medicine
Dr. Molnár F. Tamás
14 Romantic Medicine: 19th Century
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Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
26
Dr. Molnár F. Tamás
15 Germs and Miazmas: age of bacteriology
Dr. Molnár F. Tamás
16 Medicine and Surgery: WW1
Dr. Molnár F. Tamás
17 Century of Surgery and Images
Dr. Molnár F. Tamás
18 Medicine and Surgery: WW2
Dr. Molnár F. Tamás
19 Medicine till the New Milleneum and beyond
Dr. Molnár F. Tamás
20 Special topics: Plagues from Athen to COVID-19
Dr. Molnár F. Tamás
21 Special topics: Medicines from the nicotin to the target therapy
Dr. Molnár F. Tamás
22 Special topics. syndromes, names, ancestors
Dr. Molnár F. Tamás
23 Q&A, Course closing
Dr. Molnár F. Tamás
24 Q&A, Course closing
Dr. Molnár F. Tamás
Practices
Seminars
Exam topics/questions
Essay regarding any topic related to the theme of the lectures.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
27
OPE-KP1-T BASICS OF CHEMISTRY 1
Course director: DR. PÁL PERJÉSI, professor
Department of Pharmaceutical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – 30 Prerequisites: -
Topic
The course provides an overview of the basic laws of Chemistry concentrating on those that are ubiquitous in the chemistry-related
subjects of the basic modules of the health-related curriculums. The course helps understanding the chemistry-related compulsory
subjects of the modules.
Conditions for acceptance of the semester
The course is in accord with the Code of Studies and Examinations. Participation in the lectures is obligatory. Maximum three absences
can be accepted both from lectures and practices.
Two written will be written during the semester. The result of one of them should be at least 60%, the average of the two should be at
least 50%. The result of the improving test is combined with those of the two midterm tests.
Mid-term exams
Two written will be written during the semester. The result of one of them should be at least 60%, the average of the two should be at
least 50%. The result of the improving test is combined with those of the two midterm tests
Making up for missed classes
There is no opportunity to make up missed classes.
Reading material
- Obligatory literature
Ebbing D.D., Gammon S.D.: General Chemistry, Houghton Miffilin Co., Boston, 2009
- Literature developed by the Department
Almási A., Kuzma M., Perjési P.: General and Inorganic Chemistry - Laboratory Techniques and Practices, electronic educational
material, University of Pécs, 2014
- Notes
- Recommended literature
en.wikibooks.org/wiki/General_Chemistry
Lectures
1 The electronic structure of atom. Elements.
Dr. Perjési Pál
2 The electronic structure of atom. Elements.
Dr. Perjési Pál
3 Chemical bonds. Geometry of molecules.
Dr. Perjési Pál
4 Chemical bonds. Geometry of molecules.
Dr. Perjési Pál
5 Kinetic theory of gases. Gas laws.
Dr. Perjési Pál
6 Kinetic theory of gases. Gas laws.
Dr. Perjési Pál
7 Liquids and solutions. Concentrations.
Dr. Perjési Pál
8 Liquids and solutions. Concentrations.
Dr. Perjési Pál
9 Colligative properties.
Dr. Perjési Pál
10 Colligative properties.
Dr. Perjési Pál
11 Chemical thermodynamics I.
Dr. Perjési Pál
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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28
12 Chemical thermodynamics I.
Dr. Perjési Pál
13 Chemical kinetics.
Dr. Perjési Pál
14 Chemical kinetics.
Dr. Perjési Pál
15 Chemical equilibrium I. Homogeneous equilibria.
Dr. Perjési Pál
16 Chemical equilibrium I. Homogeneous equilibria.
Dr. Perjési Pál
17 Chemical equilibrium II. Acid-base equilibriums in solution.
Dr. Perjési Pál
18 Chemical equilibrium II. Acid-base equilibriums in solution.
Dr. Perjési Pál
19 Chemical equilibrium III. Heterogeneous equilibria.
Dr. Perjési Pál
20 Chemical equilibrium III. Heterogeneous equilibria.
Dr. Perjési Pál
21 Chemical equilibrium IV. Chemical thermodynamics II.
Dr. Perjési Pál
22 Chemical equilibrium IV. Chemical thermodynamics II.
Dr. Perjési Pál
23 Electrochemistry I. Conductivity of electrolytes.
Dr. Perjési Pál
24 Electrochemistry I. Conductivity of electrolytes.
Dr. Perjési Pál
25 Electrochemistry II. Electrode potential. Galvanic cells.
Dr. Perjési Pál
26 Electrochemistry II. Electrode potential. Galvanic cells.
Dr. Perjési Pál
27 Electrochemistry III. Electrolysis.
Dr. Perjési Pál
28 Electrochemistry III. Electrolysis.
Dr. Perjési Pál
Practices
Seminars
Exam topics/questions
Written tests covering the topics of the lectures.
Participants
Dr. Perjési Pál (F4H45V)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
29
OPE-N06-T MEDICAL TERMINOLOGY
Course director: DR. KATALIN EKLICS-LEPENYE, assistant professor
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 12 lectures + 0 practices + 12 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 275 Prerequisites: -
Topic
Introduction into the basics of Medical Terminology pertaining to anatomical and clinical aspects focusing on word building and breaking
down medical terms.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
A midterm test during week 6.
End-of-term test during week 12.
Making up for missed classes
To be discussed with the instructor.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
University Script
Donáth, Tibor: Lexicon Anatomiae. Anatomical Dictionary, Semmelweis, Bp. 1999
Jean Tannis Dennerll: Medical Terminology Made Easy, Delmar Publishers Inc., New York 1991
Lectures
1 Introduction into Medical Terminology. The importance of Medical terminology in practice.
Eklicsné Dr. Lepenye Katalin
2 Terminology of diseases and diagnosis.
Eklicsné Dr. Lepenye Katalin
3 Body structure. Anatomical directions, body planes.
Eklicsné Dr. Lepenye Katalin
4 Anatomical terminology of he skeletal system and the skull.
Eklicsné Dr. Lepenye Katalin
5 Terminology of continuous and discontinuous connections and the muscular system.
Eklicsné Dr. Lepenye Katalin
6 Terminology of the cardiovascular system and the heart.
Eklicsné Dr. Lepenye Katalin
7 Terminology of the respiratory system.
Eklicsné Dr. Lepenye Katalin
8 Terminology of the digestive system.
Eklicsné Dr. Lepenye Katalin
9 Terminology of the urinary system.
Eklicsné Dr. Lepenye Katalin
10 Terminology of the male reproductive system.
Eklicsné Dr. Lepenye Katalin
11 Terminology of the female reproductive system.
Eklicsné Dr. Lepenye Katalin
12 Terminology of the sensory organs.
Eklicsné Dr. Lepenye Katalin
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30
Practices
Seminars
1 Structure of Medical Terminology. Prefixes, suffixes, word roots. Introduction to clinical terminology.
2 Terminology of diseases.
3 Terminology of diagnosis.
4 Body structure. Anatomical directions, orientation; body planes.
5 Bones of the human body. Terminology of the skeletal system.
6 Mid-term test
7 Terminology of the muscular system.
8 Terminology of the heart and cardiovascular system.
9 Terminology of the respiratory system.
10 Terminology of the digestive system.
11 Revision
12 End-of-term test
Exam topics/questions
Anatomical and clinical terminology of the locomotor, cardiovascular, respiratory and digestive systems.
Participants
Eklicsné Dr. Lepenye Katalin (JMXXSC), Nagy Renáta (JR0PVR), Ronczykné Berta Anikó (CJZOFU)
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31
OPE-SKS-T INORGANIC CHEMISTRY CALCULATIONS
Course director: DR. ZSUZSANNA ROZMER, assistant professor
Department of Pharmaceutical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – 70 Prerequisites: -
Topic
This subject is based on the acquired theoretical knowledge on General and Inorganic Chemistry, with adaptation of the principles to
solve chemical problems. The aim of this course to solve chemical calculations related to the lessons of General and Inorganic Chemistry
1 and give a support for easier understanding of the subject.
Conditions for acceptance of the semester
According to the Code of Studies and Examinations (see on the homepage). During the semester maximum 3 missed classes are
acceptable. Two midterm tests will be written during the semester on the 7th and the 12th weeks. The result of both tests should be above
60%. One re-take chance is allowed.
Mid-term exams
Two written exams during the semester.
Making up for missed classes
There is no opportunity to make up missed classes.
Reading material
- Obligatory literature
Ebbing D.D., Gammon S.D.: General Chemistry, Houghton Miffilin Co., Boston, 2009.
- Literature developed by the Department
Almási A., Kuzma M., Perjési P.: General and Inorganic Chemistry - Laboratory Techniques and Calculations, electronic educational
material, University of Pécs, 2014
- Notes
- Recommended literature
en.wikibooks.org/wiki/General_Chemistry
Lectures
Practices
Seminars
1 Introduction to the calculations on inorganic chemistry (basis of chemistry). Stochiometric calculations.
Dr. Rozmer Zsuzsanna
2 Introduction to the calculations on inorganic chemistry (basis of chemistry). Stochiometric calculations.
Dr. Rozmer Zsuzsanna
3 Stochiometric calculations. Calculation of concentrations.
Dr. Rozmer Zsuzsanna
4 Stochiometric calculations. Calculation of concentrations.
Dr. Rozmer Zsuzsanna
5 Calculation of concentrations, Solubility.
Dr. Rozmer Zsuzsanna
6 Calculation of concentrations, Solubility.
Dr. Rozmer Zsuzsanna
7 Electrolytic dissociation.
Dr. Rozmer Zsuzsanna
8 Electrolytic dissociation.
Dr. Rozmer Zsuzsanna
9 Kolligative properites.
Dr. Rozmer Zsuzsanna
10 Kolligative properites.
Dr. Rozmer Zsuzsanna
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11 Thermochemistry (Hess’ Law).
Dr. Rozmer Zsuzsanna
12 Thermochemistry (Hess’ Law).
Dr. Rozmer Zsuzsanna
13 Chemical kinetics. Test 1
Dr. Rozmer Zsuzsanna
14 Chemical kinetics. Test 1
Dr. Rozmer Zsuzsanna
15 pH calculations I.: Hydrolysis of salts.
Dr. Rozmer Zsuzsanna
16 pH calculations I.: Hydrolysis of salts.
Dr. Rozmer Zsuzsanna
17 pH calculations II: Buffers.
Dr. Rozmer Zsuzsanna
18 pH calculations II: Buffers.
Dr. Rozmer Zsuzsanna
19 Solubility equilibria.
Dr. Rozmer Zsuzsanna
20 Solubility equilibria.
Dr. Rozmer Zsuzsanna
21 Calculations based on the balancing of redox equations I
Dr. Rozmer Zsuzsanna
22 Calculations based on the balancing of redox equations I
Dr. Rozmer Zsuzsanna
23 Calculations based on the balancing of redox equations II
Dr. Rozmer Zsuzsanna
24 Calculations based on the balancing of redox equations II
Dr. Rozmer Zsuzsanna
25 Calculations on electrochemistry I. Test 2
Dr. Rozmer Zsuzsanna
26 Calculations on electrochemistry I. Test 2
Dr. Rozmer Zsuzsanna
27 Calculations on electrochemistry II
Dr. Rozmer Zsuzsanna
28 Calculations on electrochemistry II
Dr. Rozmer Zsuzsanna
Exam topics/questions
The final grade is established based on the average of each written exams.
Participants
Dr. Kenari Fatemeh (PLZ1CG), Dr. Mészáros Petra (C705FN), Dr. Rozmer Zsuzsanna (IIDYH7), Dr. Tyukodi Levente (IWJHJA),
Fülöpné Kiss Edit (ZBUTWT)
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33
OPE-GOM-T POISONOUS MUSHROOMS
Course director: DR. LORÁND BARTHÓ, professor
Department of Pharmacology and Pharmacotherapy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 25 Prerequisites: -
Topic
Family physicians may play an important role in the early identification and management of mushroom poisoning (MP).
This course:
- deals with the various types of MP and their symptoms;
- molecular mechanisms encountered with the effects of cytotoxic MPs
- morphological features of the most important toxic mushrooms/fungi and their edible counterparts.
Conditions for acceptance of the semester
- Attending at least 75% of the lessons, passing the oral exam
- Oral exam includes matters of poisonings, as well as recognizing the most important PMs and their edible counterparts
Mid-term exams
Exam on week 12
Making up for missed classes
Individual
Reading material
- Obligatory literature
--
- Literature developed by the Department
CD prepared by Prof. Barthó
Most terms will be explained in the lectures.
- Notes
--
- Recommended literature
--
Lectures
1 Introduction
Dr. Barthó Loránd
2 Amanitas, Lepiotas (parasols) and their poisonings
Dr. Barthó Loránd
3 Amanitas, Lepiotas (parasols) and their poisonings
Dr. Barthó Loránd
4 Amanitas, Lepiotas (parasols) and their poisonings
Dr. Barthó Loránd
5 Amanitas, Lepiotas (parasols) and their poisonings
Dr. Barthó Loránd
6 Other mushrooms with white spores and their poisonings
Dr. Barthó Loránd
7 Other mushrooms with white spores and their poisonings
Dr. Barthó Loránd
8 Mushrooms with pink, brown or black spores
Dr. Barthó Loránd
9 Mushrooms with pink, brown or black spores
Dr. Barthó Loránd
10 Mushrooms with pink, brown or black spores
Dr. Barthó Loránd
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34
11 Mushrooms with tubes, pores, wrinkles or spines
Dr. Barthó Loránd
12 Mushrooms with tubes, pores, wrinkles or spines
Dr. Barthó Loránd
13 Molecular mechanisms encountered with the effects of cytotoxic MPs
Dr. Szeberényi József
14 Molecular mechanisms encountered with the effects of cytotoxic MPs
Dr. Szeberényi József
15 Morels, false morels, puff-balls, corals, etc. Pre-exam
Dr. Barthó Loránd
16 Morels, false morels, puff-balls, corals, etc. Pre-exam
Dr. Barthó Loránd
17 Some forensic aspects of MPs
Dr. Barthó Loránd
18 Muscarine, muscimol, ibotenic acid
Dr. Barthó Loránd
19 Coprin, orellanin, aflatoxin
Dr. Barthó Loránd
20 Reprise of poisonous mushrooms
Dr. Barthó Loránd
21 Toxins of moulds
Dr. Barthó Loránd
22 Tasks of GP sin case of MP
Dr. Barthó Loránd
23 Reprise of types of poisoning; Exam
Dr. Barthó Loránd
24 Exam
Dr. Barthó Loránd
Practices
Seminars
Exam topics/questions
Oral exam including matters of poisonings, as well as recognizing the most important PMs and their edible counterparts
Cytotoxic MPs
Gastrointestinal MP
Muscarine-type of MP
Psychotropic MP
Other types of MP
Tasks of the general practitioner in case of MP
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
35
OPE-BFA-T PHYSICAL BASIS OF BIOPHYSICS
Course director: DR. EMŐKE BÓDIS, assistant professor
Department of Biophysics [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 100 Prerequisites: -
Topic
The course addresses the chapters of physics which are necessary for a proper understanding of Biophysics (lecture and practicals).
Beyond theoretical discussions, example problems are solved.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
No midterm exam.
Making up for missed classes
There is no option.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
Course related information can be found on the website of PotePedia.
- Recommended literature
As a base, any secondary school physics book is useful.
Lectures
Practices
Seminars
1 Mathematical basics. Scalars and vectors
Dr. Visegrády Balázs
2 Physical quantities and units
Dr. Visegrády Balázs
3 Motion on a straight line. Kinematics
Dr. Pasitka Jonatán
4 Circular motion.
Dr. Pasitka Jonatán
5 Force, Newton's laws.
Dr. Pasitka Jonatán
6 Dynamics, types of forces
Dr. Pasitka Jonatán
7 Work and energy. Friction.
Dr. Grama László
8 Conservation of mechanical energy.
Dr. Grama László
9 Rotational motion. Torque.
Dr. Visegrády Balázs
10 Equilibrium.
Dr. Visegrády Balázs
11 Momentum, conservation of momentum
Dr. Pasitka Jonatán
12 Angular momentum, conservation of angular momentum
Dr. Pasitka Jonatán
13 Oscillations.
Leipoldné Dr. Vig Andrea Teréz
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36
14 Waves.
Leipoldné Dr. Vig Andrea Teréz
15 Internal energy, heat, temperature
Leipoldné Dr. Vig Andrea Teréz
16 1st and 2nd laws of thermodynamics.
Leipoldné Dr. Vig Andrea Teréz
17 Hydrostatics.
Dr. Grama László
18 Hydrodynamics.
Dr. Grama László
19 Electricity.
Dr. Visegrády Balázs
20 Magnetism.
Dr. Visegrády Balázs
21 Electromagnetic waves.
Dr. Grama László
22 Optics.
Dr. Grama László
23 Test writing
Dr. Visegrády Balázs
24 Test writing
Dr. Visegrády Balázs
Exam topics/questions
Can be found on the website of PotePedia.
The seminar strengthens physics theoretical background and provide further understanding through evaluation of exercises (calculations)
hence the written test at the end of the semester includes theoretical questions and exercises.
Participants
Dr. Bódis Emőke (FQFH76), Dr. Grama László (J7AF3B), Dr. Pasitka Jonatán (O1L51K), Dr. Visegrády Balázs (M4AZ6O), Leipoldné
Dr. Vig Andrea Teréz (OL4J1R)
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37
OPE-HPR-T HEALTH PROMOTION
Course director: DR. ISTVÁN ZOLTÁN KISS, professor
Department of Public Health Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 20 Prerequisites: -
Topic
Health promotion is intimately related not only to preventive medicine, but to the everyday practice of physicians as well. A considerable
part of noninfectious diseases is preventable, morbidity and mortality of these illnesses are decreasable by the implementation of effective
intervention.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Neptun Meet Street
Making up for missed classes
There are no make-up classes
Reading material
- Obligatory literature
- Literature developed by the Department
Education material on Neptun
- Notes
- Recommended literature
Lectures
1 Definitions of health. Health and its relation to everyday life.
Dr. Horváth-Sarródi Andrea
2 Theoretical background of health promotion. Salutogenesis and pathogenesis.
Dr. Horváth-Sarródi Andrea
3 Health promotion and health education.
Dr. Horváth-Sarródi Andrea
4 Basic documents of health promotion.
Dr. Horváth-Sarródi Andrea
5 Methods of health promotion.
Dr. Horváth-Sarródi Andrea
6 Measuring of results in health promotion activities. Evidence based health promotion.
Dr. Horváth-Sarródi Andrea
7 Health promotion and health policy.
Dr. Horváth-Sarródi Andrea
8 Lalonde model. Health in all policies (HiAP).
Dr. Horváth-Sarródi Andrea
9 Multisectorality. Stakeholders.
Dr. Horváth-Sarródi Andrea
10 Health Impact Assessment (HIA).
Dr. Horváth-Sarródi Andrea
11 Health promotion in communities.
Dr. Horváth-Sarródi Andrea
12 Health planning.
Dr. Horváth-Sarródi Andrea
13 SWOT-analysis.
Dr. Horváth-Sarródi Andrea
14 Personal health planning.
Dr. Horváth-Sarródi Andrea
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38
15 Effective health promotion in settings (schools)
Dr. Horváth-Sarródi Andrea
16 Effective health promotion in settings (work places)
Dr. Horváth-Sarródi Andrea
17 Health Promoting Universities.
Dr. Horváth-Sarródi Andrea
18 Actuality and possibilities of the concept of Health Promoting Universities.
Dr. Horváth-Sarródi Andrea
19 Methods of mental health promotion.
Dr. Horváth-Sarródi Andrea
20 Promotion of positive mental health and possibilities of prevention of mental disorders.
Dr. Horváth-Sarródi Andrea
21 Mental health policy.
Dr. Horváth-Sarródi Andrea
22 Role of physicians in the primary, secondary and tertiary levels of prevention.
Dr. Horváth-Sarródi Andrea
23 Complex health promotion programs.
Dr. Horváth-Sarródi Andrea
24 Examples for effective health promotion activities.
Dr. Horváth-Sarródi Andrea
Practices
Seminars
Exam topics/questions
Neptun Meet Street
Participants
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39
OPE-SP1-T PHARMACY BIOPHYSICS SEMINARS 1
Course director: ILDIKÓ PÉCSI, assistant professor
Department of Biophysics [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 1
Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours
Course headcount limitations (min.-max.): 5 – 100 Prerequisites: OPO-Z1E-T parallel
Topic
The course is focusing on solving problems in order to have a deeper understanding of the theory.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
During the semester the student will have to write a test solving problems.
Making up for missed classes
Missed seminars cannot be made up
Reading material
- Obligatory literature
https://aok.pte.hu/hu/egyseg/10
- Literature developed by the Department
Handouts and other online materials can be found on the departmental website (https://aok.pte.hu/hu/egyseg/10)
- Notes
https://aok.pte.hu/hu/egyseg/10
- Recommended literature
Damjanovich Sándor, Fidy Judit, Szöllősi János (eds.): Medical Biophysics, Medicina, Budapest, 2009
P.W. Atkins: Physical chemistry
Lectures
Practices
Seminars
1 Gas laws
Dr. Lukács András Szilárd
2 Energy, work, Ist law of thermodynamics
Dr. Lukács András Szilárd
3 Heat capacity, calorimetry.
Leipoldné Dr. Vig Andrea Teréz
4 Enthalpy
Leipoldné Dr. Vig Andrea Teréz
5 Carnot cycle. Classical definition of entropy
Leipoldné Dr. Vig Andrea Teréz
6 Statistical definition of entropy.
Leipoldné Dr. Vig Andrea Teréz
7 IInd law of thermodynamics
Leipoldné Dr. Vig Andrea Teréz
8 Membrane potential, Nernst equation
Pécsi Ildikó
9 Oscillatory motion
Dr. Lukács András Szilárd
10 Wave motion, interference, diffraction
Dr. Lukács András Szilárd
11 Atomic models
Dr. Szabó-Meleg Edina
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40
12 Test
Pécsi Ildikó
13 Cytoskeletal proteins
Pécsi Ildikó
14 Motor proteins
Pécsi Ildikó
Exam topics/questions
https://aok.pte.hu/hu/egyseg/10
Participants
Dr. Lukács András Szilárd (LZ2I4Q), Dr. Pasitka Jonatán (O1L51K), Karádi Kristóf Kálmán (X1QYKT), Pécsi Ildikó (ED6HUG)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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41
OPF-AR2-T ART THERAPY 2. MANAGEMENT OF PSYCHOSOMATIC DISEASES
Course director: DR. TAMÁS OLLMANN, assistant professor
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 6 lectures + 0 practices + 6 seminars = total of 12 hours
Course headcount limitations (min.-max.): 3 – 50 Prerequisites: -
Topic
Art therapy is based on the idea that the traumatic experience may not be accessible verbally but instead is locked in a subconscious
form. Metaphoric cues employed in art methods allow the delicate, ecological transformation of unpleasant experience into conscious
knowledge, and turn the emotional or physical pain into a resource. The course is focused on the management of psychosomatic diseases
(diagnosis, treatment, prevention) with the methods of art therapy. Improvement of awareness in relationships and lifestyle, work with
self-esteem, development of creative thinking and problem solving, training of focusing, generalization, and isolation of the main ideas,
improvement of verbal and fine motor skills,- are the few additional assets of the course which might be beneficial for the future
physicians. The methods are designed for persons with ordinary creative skills, thus do not require special equipment or abilities. Students
can expect informative and well-structured lectures followed by dynamic, interactive seminar classes. Topics of the second semester: art-
management of feeding disorders, respiratory diseases, sexual dysfunction and infertility, autoimmune and skin diseases.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Completed practical tasks, written test.
Making up for missed classes
Presentation on topic.
Reading material
- Obligatory literature
- Literature developed by the Department
The slides will be available.
- Notes
- Recommended literature
Lectures
1 Pain as a language of the subconscious. Psychological concept and mechanisms of pain.
Zagorácz Olga
2 Psychosomatic aspects of feeding/weight disorders. Adequate comprehension of body needs.
Zagorácz Olga
3 Psychosomatic aspects of respiratory diseases.
Zagorácz Olga
4 Psychosomatic aspects of sexual dysfunction and infertility. Types and inducing factors of sexual dysfunction.
Zagorácz Olga
5 Psychosomatic aspects of autoimmune diseases. Basics of psychotherapy in autoimmune patients.
Zagorácz Olga
6 Psychosomatic aspects of skin diseases. Development of the emotional intellect.
Zagorácz Olga
Practices
Seminars
1 Management of pain in art-therapeutic (AT) practice.
Zagorácz Olga
2 Management and prevention of feeding disorders in AT practice.
Zagorácz Olga
3 Management and prevention of respiratory diseases in AT practice.
Zagorácz Olga
4 Management and prevention of sexual dysfunction in AT practice.
Zagorácz Olga
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42
5 Management and prevention of diabetes mellitus, bronchial asthma, allergies in AT practice.
Zagorácz Olga
6 Management and prevention of skin diseases in AT practice.
Zagorácz Olga
Exam topics/questions
The topics of the lectures.
Participants
Zagorácz Olga (J5ZJ9T)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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43
OPF-BMK-T METHODS AND EXPERIMENTS IN MOLECULAR BIOLOGY
Course director: DR. KATALIN SIPOS, associate professor
Department of Pharmaceutical Biology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours
Course headcount limitations (min.-max.): 5 – 25 Prerequisites: -
Topic
We will analyze famous and interesting molecular biological experiments and examine the development and everyday importance of
methods used in molecular biology. We will pay special attention for experimental areas of pharmaceutical research. We hope the course
material will help the students to develop problemsolving thinking.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
The course will end with a written exam.
Making up for missed classes
According to personal agreement
Reading material
- Obligatory literature
- Literature developed by the Department
Scientific articles in English
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Methods to follow replication.
Dr. Sipos Katalin
2 Molecular biological methods of cell cycle examinations
Jánosa Gergely
3 PCR
Jánosa Gergely
4 Array methods
Dr. Sipos Katalin
5 Blotting methods
Pap Ramóna
6 Labeling methods in the molecular biology
Jánosa Gergely
7 Gene regulation in the prokaryotes
Dr. Sipos Katalin
8 Gene regulation in the eukaryotes.
Dr. Sipos Katalin
9 Genetically modified animals
Jánosa Gergely
10 Experimental planning in pharmaceutical research I.
Dr. Pandur Edina
11 Experimental planning in pharmaceutical research II.
Dr. Pandur Edina
12 Real time PCR
Pap Ramóna
13 Methods in cell culture experiments
Pap Ramóna
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44
14 Exam
Dr. Sipos Katalin
Exam topics/questions
No extra exam questions. The basis of the exam is the material of the seminars.
Participants
Dr. Pandur Edina (ZP0077), Dr. Sipos Katalin (RUHPLE), Jánosa Gergely (U3SEOW), Pap Ramóna (OGEM0W)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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45
OPF-ETF-T PREPARATION FOR THE PHYSIOLOGY
Course director: DR. ISTVÁN SZABÓ, assistant professor
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours
Course headcount limitations (min.-max.): 3 – 20 Prerequisites: -
Topic
The purpose of the course is to assist first-year dentistry and pharmacist students in repeating high school knowledge required to
understand physiology lectures and practices through specific physiological examples.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
According to the university's regulations
Making up for missed classes
The illustrations used during the seminars and made there are available to students
Reading material
- Obligatory literature
Physiology textbooks
- Literature developed by the Department
Figures of the seminars
- Notes
Website of the Institute of Physiology: physiology.aok.pte.hu, and the own notes of students
- Recommended literature
Physiology textbooks
Lectures
Practices
Seminars
1 Arithmetics, elementary algebra
Dr. Szabó István
2 Elementary vector algebra, properties of functions
Dr. Szabó István
3 Elementary geometry, SI system of units
Dr. Szabó István
4 Newtonian mechanics, basics of fluid mechanics
Dr. Szabó István
5 Basics of thermodynamics, basic properties of gas mixtures
Dr. Szabó István
6 Basics of electronics
Dr. Szabó István
7 Basics of optics
Dr. Szabó István
8 Elementary particles of atoms, chemical bonds
Dr. Szabó István
9 Basic chemical calculations, solutions
Dr. Szabó István
10 Osmosis, pH, simple inorganic compounds and ions
Dr. Szabó István
11 Electrochemistry
Dr. Szabó István
12 Basics of organic chemistry
Dr. Szabó István
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
46
Exam topics/questions
Test questions based on the topics of seminars
Participants
Dr. Szabó István (GKFKFI)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
47
OPF-FPB-T BIOLOGICAL APPLICATIONS OF FLUORESCENCE POLARIZATION METHODS
Course director: DR. SÁNDOR KUNSÁGI-MÁTÉ, associate professor
Department of Organic and Pharmacological Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 2
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 2 – 12 Prerequisites: OGA-ALK-T completed
Topic
The property of some materials that they are showing light emission under irradiation made considerable development in studies
performed on complex biological systems. This is because considering that only a part of materials produces fluorescence and this
fluorescence is characteristic for the given material and also by the nanosecond timeframe of the fluorescence, the related methods show
high selectivity and applicable also to study the most molecular motions too. The polarization of light which is associated to the main
characteristics of the materials offers additional selectivity for the measuring techniques, therefore applicable for analytical purposes too.
In the frame of this course further the fundamentals of fluorescence polarization and the related equipments the following topics will be
discussed: immune-fluorescence, fluorescence-activated cell-selection, resonance energy transfer, applications of polarization of the
intrinsic and extrinsic protein fluorescence, investigation of the interactions and transfers of some selected toxins and drugs (antibiotics,
cytotoxic drugs) by fluorescence polarization measurements, applications in HPLC detectors and fluorescent flow cytometry. Students
will be known through the most recent scientific results about the pharmaceutical applications of the methods listed above, will have
ability for successful application of the related measuring and data-evaluating methods. The curse gives considerable support to earn the
drug-designer attitudes of pharmacists.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
One test in the 10th week, one summary prepared about the topic of lectures and one presentation prepared within the scope of the course.
Making up for missed classes
Reading material
- Obligatory literature
David Freifelder: Physical Biochemistry
- Literature developed by the Department
Slides and notes of all lectures are available electronically. All topics discussed will be associated with papers published recently.
Those papers together with the related doctoral dissertations in English will also be offered to support the teaching.
- Notes
Slides and notes of all lectures are available electronically. All topics discussed will be associated with papers published recently.
Those papers together with the related doctoral dissertations in English will also be offered to support the teaching.
- Recommended literature
Slides and notes of all lectures are available electronically. All topics discussed will be associated with papers published recently.
Those papers together with the related doctoral dissertations in English will also be offered to support the teaching.
Lectures
1 General overview on the applicability of fluorescence polarization methods in biology, experiments raises the necessity of the
applications. Anomalies obtained in measurements based on the intensity changes of fluorescence signal.
Dr. Kunsági-Máté Sándor
2 Rotation of molecules, rotational diffusion. Characteristic changes obtained during the adsorption of small molecules onto the
large surfaces.
Dr. Kunsági-Máté Sándor
3 Fundamentals of the fluorescence processes, Jablonski diagram. Effects disturbs the fluorescence measurements: Rayleigh-
scattering, Raman-scattering, inner filter effect.
Dr. Kunsági-Máté Sándor
4 Emission surfaces: fluorescence characteristics of Tripaflavin, Rheonin A, Aurophospin and of the Rodamine B.
Dr. Kunsági-Máté Sándor
5 Dependence of the fluorescence polarization on the molecular environment: the role of the viscosity and the temperature.
Dr. Kunsági-Máté Sándor
6 Correlation between the polaroization of light and the absorption and emission transitions associated to the molecular skeleton
and the related absorption and emission oscillators.
Dr. Kunsági-Máté Sándor
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
48
7 The Perrin-Ljovsin and Szvesnyikov-Feofilov equations. Expectation of the real polarization. Relationnship between the
anisotropy and the degree of polarization.
Dr. Kunsági-Máté Sándor
8 Methods to determine the real polarization spectra: extrapolation from measurements of two samples having different viscosities
and/or temperatures.
Dr. Kunsági-Máté Sándor
9 Detectors implemented in HPLC equipments and in the cytometers to measure the fluorescence polarization.
Dr. Kunsági-Máté Sándor
10 Circumstances disturbing the measurements: consideration of the inner filter effect and possibilities of their elimination. Protein
dynamics in cases of highly light-scattering samples.
Dr. Kunsági-Máté Sándor
11 Calculation the corrected polarization spectra. Consequences of Kasha-rule on fluorescence polarization, the inner quantum
efficiency.
Dr. Kunsági-Máté Sándor
12 Fine-structure of polarization spectra, connection to the vibration spectra of molecules.
Dr. Kunsági-Máté Sándor
13 Possibilities according to the determination of theoretical polarization spectra, connections to the quantum chemistry.
Dr. Kunsági-Máté Sándor
14 Measuring the polarization spectra. Right angle and front face optical rearrangements, consequences on measurements of
biological samples.
Dr. Kunsági-Máté Sándor
15 Fluorescence of conjugated aromatic molecular units, relationship between the spectral shift and the degree of conjugation.
Dr. Kunsági-Máté Sándor
16 Experimental and theoretical determination of the polarization spectra of anthracene: comparative study.
Dr. Kunsági-Máté Sándor
17 Protein dynamics: fluorescence of amino acids and advantages of the fluorescence polarization measurements. Exeptional
fluorescence and fluorescence polarization behaviors of azulene.
Dr. Kunsági-Máté Sándor
18 Inclusion complexes of aromatic amino acids formed by cavity-shaped molecules, the measurements of anisotropy lifetime.
Dr. Kunsági-Máté Sándor
19 Effect of microsolvation on the interactions of serum albumins with cavity-shaped molecules applied for molecular packing of
different drug molecules.
Dr. Kunsági-Máté Sándor
20 Determination of cell-membrane fluidity by measuring the fluorescence polarization and anisotropy decay.
Dr. Kunsági-Máté Sándor
21 Fluorescent molecular packers: determination of the microsolvation by solvent relaxation measurements.
Dr. Kunsági-Máté Sándor
22 Determination of the molecular adsorption of Citrinine onto the human serum albumin molecules by fluorescence polarization
methods.
Dr. Kunsági-Máté Sándor
23 Competition of the Citrinine molecules with drugs for the binding sites of albumins.
Dr. Kunsági-Máté Sándor
24 Determination of the molecular adsorption of Ochratoxin A onto the human serum albumin molecules by fluorescence
polarization methods.
Dr. Kunsági-Máté Sándor
25 Competition of the Ochratoxin A molecules with drugs for the binding sites of albumins.
Dr. Kunsági-Máté Sándor
26 Exchange reactions of polyphenols with toxins bonded to proteins, signal changes obtained in fluorescence polarization.
Dr. Kunsági-Máté Sándor
27 Extraction of antibiotics from vaste waters by carbon nanotubes, process followed by the fluorescence polarization.
Dr. Kunsági-Máté Sándor
28 Extraction of antibiotics from vaste waters by carbon nanotubes, process followed by the fluorescence polarization.
Dr. Kunsági-Máté Sándor
Practices
Seminars
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
49
Exam topics/questions
Rotation of molecules, rotational diffusion. Characteristic changes obtained during the adsorption of small molecules onto the large
surfaces.
Fundamentals of the fluorescence processes, Jablonski diagram. Effects disturbs the fluorescence measurements: Rayleigh-scattering,
Raman-scattering, inner filter effect.
Emission surfaces: fluorescence characteristics of Tripaflavin, Rheonin A, Aurophospin and of the Rodamine B.
Dependence of the fluorescence polarization on the molecular environment: the role of the viscosity and the temperature.
Correlation between the polaroization of light and the absorption and emission transitions associated to the molecular skeleton and the
related absorption and emission oscillators.
The Perrin-Ljovsin and Szvesnyikov-Feofilov equations. Expectation of the real polarization. Relationnship between the anisotropy and
the degree of polarization.
Methods to determine the real polarization spectra: extrapolation from measurements of two samples having different viscosities and/or
temperatures.
Detectors implemented in HPLC equipments and in the cytometers to measure the fluorescence polarization.
Circumstances disturbing the measurements: consideration of the inner filter effect and possibilities of their elimination. Protein dynamics
in cases of highly light-scattering samples.
Calculation the corrected polarization spectra. Consequences of Kasha-rule on fluorescence polarization, the inner quantum efficiency.
Fine-structure of polarization spectra, connection to the vibration spectra of molecules.
Possibilities according to the determination of theoretical polarization spectra, connections to the quantum chemistry.
Measuring the polarization spectra. Right angle and front face optical rearrangements, consequences on measurements of biological
samples.
Fluorescence of conjugated aromatic molecular units, relationship between the spectral shift and the degree of conjugation.
Experimental and theoretical determination of the polarization spectra of anthracene: comparative study.
Protein dynamics: fluorescence of amino acids and advantages of the fluorescence polarization measurements. Exeptional fluorescence
and fluorescence polarization behaviors of azulene.
Inclusion complexes of aromatic amino acids formed by cavity-shaped molecules, the measurements of anisotropy lifetime.
Effect of microsolvation on the interactions of serum albumins with cavity-shaped molecules applied for molecular packing of different
drug molecules.
Determination of cell-membrane fluidity by measuring the fluorescence polarization and anisotropy decay.
Fluorescent molecular packers: determination of the microsolvation by solvent relaxation measurements.
Determination of the molecular adsorption of Citrinine onto the human serum albumin molecules by fluorescence polarization methods.
Competition of the Citrinine molecules with drugs for the binding sites of albumins.
Determination of the molecular adsorption of Ochratoxin A onto the human serum albumin molecules by fluorescence polarization
methods.
Competition of the Ochratoxin A molecules with drugs for the binding sites of albumins.
Exchange reactions of polyphenols with toxins bonded to proteins, signal changes obtained in fluorescence polarization.
Extraction of antibiotics from vaste waters by carbon nanotubes, process followed by the fluorescence polarization.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
50
OPF-H2A-T MEDICAL HUNGARIAN 2A - COMMUNICATION SKILLS
Course director: DR. VILMOS WARTA, associate professor
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 2 – 25 Prerequisites: OPF-H1A-T completed + OPF-H2B-T parallel
Topic
This course is meant to serve as a transition between general and specific (doctor-patient) communication skills development.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Making up for missed classes
In the case of absences up to 25% of total class time, oral examination will have to be taken.
Reading material
- Obligatory literature
Anamnézis magyarul (Magyar orvosi szaknyelv kezdőknek) by Renáta Halász, 2015. Pécs
- Literature developed by the Department
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag
- Notes
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
- Recommended literature
Lectures
Practices
Seminars
1 Logical relations, comparison
2 Logical relations, comparison
3 Giving orientation, informing people
4 Giving orientation, informing people
5 Giving descriptions, requesting and providing information
6 Giving descriptions, requesting and providing information
7 Cause and consequence
8 Medication and effects
9 Narratives
10 Narratives
11 Giving advice
12 Giving advice
13 Expressing uncertainty
14 Expressing uncertainty
15 Test 1
16 Test 1
17 Descriptions, warning
18 Descriptions, warning
19 Polite request, command and warning
20 Polite request, command and warning
21 Parts of the human body, pain, basic symptoms
22 Parts of the human body, pain, basic symptoms
23 History taking: presenting complaints, location, direction and character of pain
24 Test 2.
Exam topics/questions
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
51
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Nagy Renáta (JR0PVR), Ronczykné Berta Anikó (CJZOFU), Szalai-
Szolcsányi Judit (RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
52
OPF-H2B-T MEDICAL HUNGARIAN 2B - LANGUAGE POINTS
Course director: DR. VILMOS WARTA, associate professor
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OPF-H1B-T completed + OPF-H2A-T parallel
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
This course is meant to provide the language basis for advanced communication between doctors and patients.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Making up for missed classes
To be discussed with the course tutor.
Reading material
- Obligatory literature
Anamnézis magyarul (Magyar orvosi szaknyelv kezdőknek) by Renáta Halász, 2015. Pécs
- Literature developed by the Department
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Expressing possessing, genitive case
2 Expressing possessing, genitive case
3 Adjectives and nouns: eg. nátha-náthás, nominalization: eg köhög-köhögés
4 Adjectives and nouns: eg. nátha-náthás, nominalization: eg köhög-köhögés
5 Question words, concerning time and location and adverbs of time
6 Question words, concerning time and location and adverbs of time
7 Expressing cause, giving explanation
8 Expressing cause, giving explanation
9 Functions of past tense in medical Hungarian
10 Functions of past tense in medical Hungarian
11 Future tense, modality expressing ability and volition
12 Future tense, modality expressing ability and volition
13 Impersonalization
14 Impersonalization
15 Consolidation test 1
16 Test 1
17 Modality expressing necessity, possibility and prohibition
18 Modality expressing necessity, possibility and prohibition
19 Definite and indefinite conjugation, prefixed verbs
20 Definite and indefinite conjugation, prefixed verbs
21 Imperative forms
22 Imperative forms
23 Giving instructions to patients
24 Test 2.
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
53
Exam topics/questions
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Nagy Renáta (JR0PVR), Ronczykné Berta Anikó (CJZOFU), Szalai-
Szolcsányi Judit (RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
54
OPF-IZM-T MOLECULAR BASIS OF MUSCLE FUNCTION
Course director: DR. DÉNES LŐRINCZY, professor emeritus
Department of Biophysics [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 30 Prerequisites:
Topic
The structure of muscle based on light, phase contrast, polarized and electron microscopic observations. Elastic behaviour of passive and
active muscle, types of muscle contractions, muscle force-length relationship. Work done by the muscle, muscle efficiency and heat
production. Thermoelastic behaviour of muscle. Muscle models based on mechanical and structural investigations. Bioelectrical
phenomena, excitation-contraction coupling. Energetics of muscle function, structure of muscle proteins (actin, myosin etc.), analysis of
sliding model. Energetic and spectroscopic investigations in the research of molecular dynamic and thermodynamic background of
muscle function.
Conditions for acceptance of the semester
The applicants - in the case of more than one absence (up to maximum three absences in which must not be the consultation or test) -
should prepare and will be tested from the missed topics given by the instructor. In the case of more than three absences the course can
not be accepted.
Mid-term exams
Written test at the end of semester.
Making up for missed classes
The applicants - in the case of more than one absence (up to maximum three absences in which must not be the consultation or test) -
should prepare and will be tested from the missed topics given by the instructor.
Reading material
- Obligatory literature
- Literature developed by the Department
It will be announced at the beginning of the course depending on the possibilities of libraries of Biophysical Department, Faculty of
Medicine. A permanent source could be the roaming in the Internet.
- Notes
- Recommended literature
Lectures
1 The composition of muscle.
Dr. Lőrinczy Dénes
2 The sorts of muscle.
Dr. Lőrinczy Dénes
3 The structure of muscle on the basis of light, phasecontrast and polarization microscope.
Dr. Lőrinczy Dénes
4 Structure of muscle by ELMI.
Dr. Lőrinczy Dénes
5 Sorts of muscle contraction.
Dr. Lőrinczy Dénes
6 Elastic behaviour of passive and active muscle.
Dr. Lőrinczy Dénes
7 Muscle force and length relationship, Hill`s equation.
Dr. Lőrinczy Dénes
8 Work and heat production done by a muscle, efficiency of muscle function.
Dr. Lőrinczy Dénes
9 Thermoelastic behaviour of muscle.
Dr. Lőrinczy Dénes
10 Muscle models proposed by mechanical and structural investigations.
Dr. Lőrinczy Dénes
11 Biochemical basis and energetics of muscle function.
Dr. Lőrinczy Dénes
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
55
12 Bioelectrical phenomena. Action potentials.
Dr. Lőrinczy Dénes
13 Nernst equation, G-H-K equation.
Dr. Lőrinczy Dénes
14 Voltage- and patch-clamp techniques.
Dr. Lőrinczy Dénes
15 Excitation-contraction coupling.
Dr. Lőrinczy Dénes
16 Structure of muscle proteins (actin and myosin, actomyosin complex).
Dr. Lőrinczy Dénes
17 Discussion of sliding model in details (x-ray diffraction).
Dr. Lőrinczy Dénes
18 Molecular dynamic background of muscle contraction (EPR spectroscopy)
Dr. Lőrinczy Dénes
19 Muscle in the sport and rehabilitation (wellness).
Dr. Lőrinczy Dénes
20 Principle of differential scanning calorimetry.
Dr. Lőrinczy Dénes
21 Thermodynamic background of muscle contraction (DSC results)
Dr. Lőrinczy Dénes
22 Muscle and levers in locomotion.
Dr. Lőrinczy Dénes
23 Written test.
Dr. Lőrinczy Dénes
24 Written test.
Dr. Lőrinczy Dénes
Practices
Seminars
Exam topics/questions
Written test
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
56
OPF-MGY-T MEDICINAL PLANTS IN THE MECSEK MOUNTAIN
Course director: DR. NÓRA PAPP, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 16 lectures + 8 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 15 Prerequisites: -
Topic
The course includes 8x2 lectures and 3 practices (2 + 2x3). The aim of the course is to practice the correct identification of medicinal
plants including the main morphological characters, habitat, collection place, and therapeutical use of the species. The course gives a
general overview on the most frequently used medicinal plants, protected and cultivated species, as well as various vegetation types in
the Mecsek mountain and its environment. In addition, the effect and relationship between abiotic factors and secondary metabolites of
plants are also discussed, which can provide recommendations for collection place and habitat of plants.
Conditions for acceptance of the semester
Maximal absences: 2 /semester.
Mid-term exams
Fulfillment of 2 tests based on the lectures and practices.
Making up for missed classes
http://gytk.pte.hu/en/egyseg/oktatasianyagok/1640
http://aok.pte.hu/en/egyseg/oktatasianyagok/1640
Teaching supplements in Neptun /MS Teams.
Reading material
- Obligatory literature
- Literature developed by the Department
Lectures in Neptun / MS Teams.
- Notes
- Recommended literature
Lectures
1 Definitions related to vegetations of medicinal plants, ecological characters of habitats
Dr. Papp Nóra
2 Definitions related to vegetations of medicinal plants, ecological characters of habitats
Dr. Papp Nóra
3 Environmental adaptation of medicinal plants (morphology, phytochemistry); relationship among medicinal plant populations
and their environment with case studies
Dr. Papp Nóra
4 Environmental adaptation of medicinal plants (morphology, phytochemistry); relationship among medicinal plant populations
and their environment with case studies
Dr. Papp Nóra
5 Vegetations in the Mecsek mountain I: medicinal plants of oakwoods, hornbeam-oak forests, beech and karst shrub forests
Dr. Papp Nóra
6 Vegetations in the Mecsek mountain II: medicinal plants of rock grasses, swamps and alder gallery forests
Dr. Papp Nóra
7 Medicinal plants at road edge vegetations; protected and cultivated plants in the Mecsek mountain
Dr. Papp Nóra
8 Medicinal plants at road edge vegetations; protected and cultivated plants in the Mecsek mountain
Dr. Papp Nóra
9 Field work methods for identification of medicinal plants
Dr. Papp Nóra
10 Field work methods for identification of medicinal plants
Dr. Papp Nóra
11 Field study of medicinal plants by handout
Dr. Papp Nóra
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
57
12 Field study of medicinal plants by handout
Dr. Papp Nóra
13 Study and evaluation of field diaries on medicinal plants I.
Dr. Papp Nóra
14 Study and evaluation of field diaries on medicinal plants I.
Dr. Papp Nóra
15 Study and evaluation of field diaries on medicinal plants II., Written test
Dr. Papp Nóra
16 Study and evaluation of field diaries on medicinal plants II., Written test
Dr. Papp Nóra
Practices
17 Medicinal plants of the Mecsek mountain on herbaria
Dr. Papp Nóra
18 Medicinal plants of the Mecsek mountain on herbaria
Dr. Papp Nóra
19 Medicinal plants in oakwood forest (Dömörkapu)
Dr. Papp Nóra
20 Medicinal plants in oakwood forest (Dömörkapu)
Dr. Papp Nóra
21 Medicinal plants in oakwood forest (Dömörkapu)
Dr. Papp Nóra
22 Plants in the EGSC-Melius Medicinal Plant Garden
Dr. Papp Nóra
23 Plants in the EGSC-Melius Medicinal Plant Garden
Dr. Papp Nóra
24 Plants in the EGSC-Melius Medicinal Plant Garden
Dr. Papp Nóra
Seminars
Exam topics/questions
According to the topics of the course.
Participants
Dr. Papp Nóra (S3PA4G)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
58
OPF-N04-T ANATOMICAL TERMINOLOGY
Course director: DR. KATALIN EKLICS-LEPENYE, assistant professor
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: -
Topic
The course aims to mediate the basic anatomical terms supporting the studies of anatomy.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Midterm test during week 6.
End-of-term test during week 12.
Making up for missed classes
To be discussed with the instructor.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
University Script
Donáth, Tibor: Lexicon Anatomiae. Anatomical Dictionary, Semmelweis, Bp. 1999.
Lectures
Practices
Seminars
1 Structure of anatomical terms.
Terminology of the compact and trabecular bones.
Body Planes, anatomical directions.
2 Structure of anatomical terms.
Terminology of the compact and trabecular bones.
Body Planes, anatomical directions.
3 Surface Features of Bones, Scapula, humerus.
4 Surface Features of Bones, Scapula, humerus.
5 Terminology of the joints. Upper extremity.
6 Terminology of the joints. Upper extremity.
7 Anatomical Terminology of the lower extremity, bones, joints.
8 Anatomical Terminology of the lower extremity, bones, joints.
9 Anatomical Terminology of the Pelvic Girdle. Bones, ligaments, joints.
10 Anatomical Terminology of the Pelvic Girdle. Bones, ligaments, joints.
11 Mid-term test
12 Mid-term test
13 Vertebrae, sternum, costae. Terminology of the vertebral column.
14 Vertebrae, sternum, costae. Terminology of the vertebral column.
15 Terminology of the ligaments and joints of the vertebral column.
16 Terminology of the ligaments and joints of the vertebral column.
17 Anatomical Terminology of the muscular system.
18 Anatomical Terminology of the muscular system.
19 Anatomical terminology of the skull. Calvaria, internal cranial base.
20 Anatomical terminology of the skull. Calvaria, internal cranial base.
21 Anatomical terminology of the skull. External cranial base.
22 Anatomical terminology of the skull. External cranial base.
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23 End-of-term test.
24 Retake test for those who happen to fail the end-of-term.
Exam topics/questions
Anatomical terminology of the locomotor system (bones, joints, muscles and the skull).
Participants
Eklicsné Dr. Lepenye Katalin (JMXXSC), Nagy Renáta (JR0PVR), Ronczykné Berta Anikó (CJZOFU)
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60
OPF-NS2-T NOBEL PRIZE AWARDED CELL BIOLOGY II
Course director: DR. MARIANNA PAP, associate professor
Department of Medical Biology and Central Electron Microscope Laboratory [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 200 Prerequisites: -
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
The aim of the course is to present the most important and most exciting Nobel Prize-winning molecular cell biology discoveries based
on Nobel lectures given by the winners. The background story of the awards reveals many years of research work, good ideas, good
fortune mixed with family and other personal memories. There is no single recipe for success, the road is always a bit different, and
perhaps the only common feature is the teamwork. From the presentations one might get insight of the winners” personality as well. An
important aspect was in the selection of the topics to emphasize their significance (DNA-, RNA-structure and their synthesis, ribosome
function), their impact on current medical way of thinking (e.g. Prions) and diagnostic methods (e.g. recombinant DNA technology,
DNA sequencing), the description of their present and future medical applicability (e.g. in vitro fertilization), as well as to highlight their
potential relations to different diseases (e.g. cell cycle regulation, reprogram of differentiated cells, RNA interference, papillomaviruses,
HIV). Lectures are organized based on the topics related to the weekly schedule of the molecular cell biology course, not in chronological
order. Most of the presented discoveries and experiments are involved in the molecular cell biology course material, so hopefully their
discussion helps in the better understanding of those topics and lead to a more effective and shorter exam preparation.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
2 written tests: on week 7 and on week 14.
Making up for missed classes
Participation on Hungarian or German lectures is the only possibility to make-up missed lectures.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
www.nobelprize.org
Lectures
1 Passive transport
Dr. Pap Marianna
2 Passive transport
Dr. Pap Marianna
3 Active transport
Dr. Pap Marianna
4 Action of hormones
Dr. Pap Marianna
5 G-proteins and their role in signal transduction
Dr. Pap Marianna
6 G-protein coupled receptors
Dr. Pap Marianna
7 Growth factors
Dr. Pap Marianna
8 Growth factors
Dr. Pap Marianna
9 Reversible protein phosphorylation in signal transduction pathways
Dr. Pap Marianna
10 Reversible protein phosphorylation in signal transduction pathways
Dr. Pap Marianna
11 Genetic control of early embryonic development
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Dr. Pap Marianna
12 Genetic control of early embryonic development
Dr. Pap Marianna
13 Programmed cell death
Dr. Pap Marianna
14 Programmed cell death
Dr. Pap Marianna
15 DNA tumor viruses
Dr. Pap Marianna
16 DNA tumor viruses
Dr. Pap Marianna
17 RNA tumor viruses
Dr. Pap Marianna
18 Retroviral oncogenes
Dr. Pap Marianna
19 Telomeres and telomerase activity in cancers
Dr. Pap Marianna
20 Human cell- and tissue transplantation
Dr. Pap Marianna
21 In vitro fertilization
Dr. Pap Marianna
22 The discovery of the green fluorescent protein and its significance in molecular biology
Dr. Pap Marianna
23 Exam
Dr. Pap Marianna
24 Exam
Dr. Pap Marianna
Practices
Seminars
Exam topics/questions
.
Participants
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62
OPF-PLH-T THE PLACEBO EFFECT
Course director: TIBOR SZOLCSÁNYI, assistant professor
Department of Behavioural Sciences [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 50 Prerequisites: -
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
The use of placebo effect has been an inherent part of medicine for thousands of years, and in the recent decades it has become an
inevitable element of medical research due to the introduction of placebo controlled clinical trials. In spite of this fact the research
methodology to measure the effectiveness of placebo effect has been clarified only in the last 10-15 years. At the same time researches
on the neurochemical mechanisms underlying the placebo effect have gained a new impetus. Currently, therefore, we have a much greater
understanding of placebo effect in the context of evidence-based medicine than before, which raises new types of ethical questions as
well. During the course we will examine the different aspects of the phenomenon of placebo effect, and the students will gain knowledge
of the current research results on the field. The main topics of the course: the history of the use of placebo therapies, the role of placebo
effect in medical research, the psycho-social factors that are able to induce placebo effect, neurochemical mechanisms underlying the
placebo effect, the ethical implications of the use of placebo effect in medical treatments.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Written test taking place in the last class. To improve the grade, the test can be repeated two times in the first two weeks of the exam
period.
Making up for missed classes
According to the Code of Studies and Examinations.
Reading material
- Obligatory literature
Franklin G. Miller; Luna Colloca; Ted J. Kaptchuk: The Placebo Effect: Illness and Interpersonal Healing, Perspect Biol Med. 2009
; 52(4)
Damien G. Finniss; Ted J. Kaptchuk; Franklin G. Miller; Fabrizio Benedetti: Biological, Clinical and Ethical Advances of Placebo
Effects, Lancet 2010; 375; 686-695
Franklin G. Miller; Donald L. Rosenstein: The Nature and Power of the Placebo Effect, Journal of Clinical Epidemiology 59, 2006;
331-335
Fabrizio Benedetti: Mechanisms of Placebo and Placebo-Related Effects across Diseases and Treatments, Annual Review of
Pharmacology and Toxicology, Vol. 48; 2008; 33-60.
Jozien M. Bensing; William Verheul: The Silent Healer: The Role of Communication in Placebo Effects, Patient Education and
Counseling 80, 2010; 293-299
- Literature developed by the Department
Additional materials: Neptun MeetStreet
- Notes
--
- Recommended literature
Fabrizio Benedetti: Placebo Effect, Oxford University Press, Oxford, 2009
Lectures
Lectures
1 Introduction, definitions of placebo effect
Dr. Szolcsányi Tibor
2 The use of placebo effect in the history of medicine
Dr. Szolcsányi Tibor
3 The use of placebo effect in the context of medical research: the introduction of randomized placebo controlled clinical trials and
its consequences
Dr. Szolcsányi Tibor
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63
4 The methodological and ethical challenges of placebo research
Dr. Szolcsányi Tibor
5 The main forms of placebo effect (expectancy based / classical conditioning / affective modulation) and their effectiveness in
different diseases
Dr. Szolcsányi Tibor
6 The neurochemistry of placebo effect: placebo analgesia
Dr. Szolcsányi Tibor
7 The neurochemistry of placebo effect: the cardiovascular and the respiratory system, immune response and hormone secretion,
Parkinson disease
Dr. Szolcsányi Tibor
8 The neurochemistry of placebo effect: further results
Dr. Szolcsányi Tibor
9 An overview of the psycho-social factors that are able to induce placebo effect
Dr. Szolcsányi Tibor
10 Pain management through psychological interventions and placebo analgesia
Dr. Szolcsányi Tibor
11 Ethical implications: how to enhance the placebo effect through improving the physician-patient relationship
Dr. Szolcsányi Tibor
12 Written test
Dr. Szolcsányi Tibor
Practices
Seminars
Exam topics/questions
--
Participants
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64
OPF-VEO-T VACCINATION, ANTI-VACCINATION MOVEMENTS: DO MORE HARM THAN GOOD
Course director: DR. KATALIN SZENDI, assistant professor
Department of Public Health Medicine [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 30 Prerequisites: -
Topic
Vaccination belongs to one of the most successful modern health care programmes that decreased significantly the number of severe
infectious diseases. In today’s world experts are unable to compete with the media. Several delusions circulate infiltrating the public
opinion related to vaccines. The most susceptible target audience of these beliefs are the half-educated laymen who believe in the media
created pseudoscience. The activity of stubborn anti-vaccine minorities can be dangerous because that may open up new chances of the
spread of infectious diseases.
The objective of the course is to deepen the knowledge of vaccinations concerning the background, benefits, achievements and failures,
and the course also serves as a thought provoking initiation for practitioners relating to possible actions against the anti-vaccination
movements.
Conditions for acceptance of the semester
Participation in lectures and practicals is obligatory which is registered.
Absences should not exceed 15% (2x45 min). Otherwise signature of grade book is denied.
Mid-term exams
Making up for missed classes
There are no make-up classes.
Reading material
- Obligatory literature
- Literature developed by the Department
Educational material uploaded on Neptun.
- Notes
- Recommended literature
Stanley A. Plotkin. History of Vaccine Development. Springer 2011.
Vaccine Fact Book 2013. http://www.phrma.org/sites/default/files/pdf/PhRMA_Vaccine_FactBook_2013.pdf
WHO, UNICEF, World Bank. State of the world’s vaccines and immunization, 3rd ed., Geneva, World Health Organization, 2009.
Lectures
Practices
Seminars
Exam topics/questions
Neptun
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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65
OPF-XC1-T EXTRACELLULAR VESICLES: BASICS, ISOLATION AND APPLICATION METHODS 1
Course director: KRISZTINA BÁNFAI, assistant lecturer
Department of Pharmaceutical Biotechnology [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 20 Prerequisites: OPO-GL1-T completed
Topic
The course provides basic knowledge of different subtypes of extracellular vesicles. It gives a historical overview and detailed role in
physiological processes. Also covers the content and major components of extracellular vesicles. Besides overall theoretical background
of the field, the course gives ability to understand the challenges in different kind of isolation methods. Gives insight into current
application methodologies and future perspectives in the research field. Also highlights several possible molecular mechanisms
modulated by exosomes. The second part of the course mainly focuses on exosomes and their practical applications.
Topics:
- Basics of extracellular vesicles
- History of extracellular vesicles
- Biogenesis and release of extracellular vesicles
- Mechanisms of extracellular vesicle uptake
- Protein content of extracellular vesicles
- RNA content of extracellular vesicles
- Lipid content of extracellular vesicles
- Isolation methods for extracellular vesicles (overview)
- Technical challenges of working with extracellular vesicles
- Exosome isolation techniques from cell culture media
- Isolation of exosomes with differential ultracentrifugation
- Exosome isolation from blood plasma and serum
- Commercial kit based isolation of exosomes
- Minimal requirements for characterization of isolated extracellular vesicles
- Current trends in EV research
- Role of exosomes during aging
- Role of exosomes during tumor development
- Exercise derived exosomes
- Exam
Skills:
The student will have the following skills:
- basic and overall knowledge of extracellular vesicles
- apply different type of isolation methods of extracellular vesicles
- comprehend/resolve pitfalls and challenges of purification and isolation of extracellular vesicles
- apply extracellular vesicle point of view on research field of interest
- plan experiments in research field of interest
- get familiar with current research areas related to extracellular vesicles
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Grade based on written tests of semester
Making up for missed classes
Attending the course classes is obligatory.
Reading material
- Obligatory literature
Winston Patrick Kuo, Shidong Jia: Extracellular Vesicles: Methods and Protocols, Springer New York, 2017, ISBN 1493972510,
9781493972517
- Literature developed by the Department
Lecture materials will be published after the class
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- Notes
Student notes on lectures
- Recommended literature
Ramirez, M. I., Amorim, M. G., Gadelha, C., Milic, I., Welsh, J. A., Freitas, V. M., et al. (2018). Technical challenges of working
with extracellular vesiclesvesicles. Nanoscale. 881-906. doi:10.1039/c7nr08360b.
Lectures
1 Basics of extracellular vesicles
Bánfai Krisztina
2 History of extracellular vesicles
Bánfai Krisztina
3 Biogenesis and release of extracellular vesicles
Garai Kitti
4 Mechanisms of extracellular vesicle uptake
Garai Kitti
5 Protein content of extracellular vesicles I.
Bánfai Krisztina
6 Protein content of extracellular vesicles II.
Bánfai Krisztina
7 RNA content of extracellular vesicles I.
Garai Kitti
8 RNA content of extracellular vesicles II.
Garai Kitti
9 Lipid content of extracellular vesicles I.
Bánfai Krisztina
10 Lipid content of extracellular vesicles II.
Bánfai Krisztina
11 Isolation methods for extracellular vesicles (overview)
Garai Kitti
12 Technical challenges of working with extracellular vesicles
Garai Kitti
13 Exosome isolation techniques from cell culture media
Bánfai Krisztina
14 Isolation of exosomes with differential ultracentrifugation
Bánfai Krisztina
15 Exosome isolation from blood plasma and serum
Garai Kitti
16 Commercial kit based isolation of exosomes
Garai Kitti
17 Minimal requirements for characterization of isolated extracellular vesicles I.
Garai Kitti
18 Minimal requirements for characterization of isolated extracellular vesicles II.
Garai Kitti
19 Current trends in EV research I.
Bánfai Krisztina
20 Current trends in EV research II.
Bánfai Krisztina
21 Role of exosomes during aging I.
Dr. Kvell Krisztián
22 Role of exosomes during aging II.
Dr. Kvell Krisztián
23 Role of exosomes during tumor development I.
Dr. Pongrácz Judit Erzsébet
24 Role of exosomes during tumor development II.
Dr. Pongrácz Judit Erzsébet
25 Exercise derived exosomes I.
Dr. Kvell Krisztián
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26 Exercise derived exosomes II.
Dr. Kvell Krisztián
27 Exam
Bánfai Krisztina
28 Exam
Garai Kitti
Practices
Seminars
Exam topics/questions
At the last class oral test is held upon the exam questions provided during the semester.
Participants
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68
OPE-ABI-T APPLIED BIOMETRICS
Course director: DR. KORNÉLIA BORBÁS-FARKAS, assistant professor
Institute of Bioanalysis [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 6 lectures + 6 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 12 Prerequisites: -
Topic
Basics of biometrical methods are indispensable to understand the scientific results, to plan own research, and to evaluate data. The main
goal of the course is to expand and deepened the basic knowledge of biometrics via solving practical problems.
Object of the course is to demonstrate different type of research with most frequently applied biometrical methods, though representative
examples or with using of the data of the participants.
Conditions for acceptance of the semester
Problem solving, oral report
Mid-term exams
Short presentation(s) on the classes by the students
Making up for missed classes
Consultation
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Andrew F. Siegel: Statistics and Data Analysis. An introduction, John Wiley & Sons, 1988
Douglas G. Altman: Practical Statistics for Medical Research, Chapman & Hall, 1994
P. Armitage and G. Berry: Statistical Methods in Medical Research, Blackwell Science, 1994
Robert R. Sokal / F. James Rohlf: Biometry, W. H. Freeman and Company, New York, 1981
Lectures
1 Introduction to research methodology, refresh the bio-statistical knowledge
Dr. Pótó László
2 Variance analysis
Borbásné Dr. Farkas Kornélia
3 Regression analysis
Dr. Pótó László
4 Correlation analysis
Borbásné Dr. Farkas Kornélia
5 Survival analysis
Borbásné Dr. Farkas Kornélia
6 Factor analysis
Borbásné Dr. Farkas Kornélia
Practices
1 Refresh the bio-statistical knowledge using the SPSS, exercises
Borbásné Dr. Farkas Kornélia
2 Variance analysis, post-hoc tests
Borbásné Dr. Farkas Kornélia
3 Linear and non-linear regression analysis
Borbásné Dr. Farkas Kornélia
4 Parametric and non-parametric(rank-) correlation analysis
Borbásné Dr. Farkas Kornélia
5 Survival analysis, Cox-regression analysis...
Borbásné Dr. Farkas Kornélia
6 Factor analysis
Borbásné Dr. Farkas Kornélia
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Seminars
Exam topics/questions
It will be given at the first practice
Participants
Borbásné Dr. Farkas Kornélia (IRWZKJ), Dr. Dergez Tímea (HPZ74N), Dr. Pótó László (FIO4UU), Kőnigné Dr. Péter Anikó (L556VJ)
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70
OPE-FKS-T PHYSICAL CHEMISTRY PROBLEM SOLVING SEMINAR
Course director: DR. LÍVIA NAGY-ZENGŐ, senior research fellow
Faculty of Natural Sciences - Department of General and Physical Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours
Course headcount limitations (min.-max.): 3 – 36 Prerequisites: OPA-PC1-T parallel
Topic
This is an elective course, a lecture room practice. It helps the student understanding the ways of calculating quantitative properties of
material, extent of changes and determine important physicochemical parameters. It shows the applicability of the theoretical forms, the
proper using of units in calculations. Showing the applicability of theory it supports bringing close to understanding the principles of
basic course on physical chemistry. The practice is an informal discussion following the physical chemistry I lecturing. The students
obtain problems to solve as home work. These problems are discussed during the practice. During the semester written test are given.
The evaluation is based on the scores. Students taking this course usually can solve easier the calculating problems at the physical
chemistry I course.
Conditions for acceptance of the semester
Two class absence can be tolerated.
Mid-term exams
The average of the results of two written tests provides the grade recommended.
Making up for missed classes
Full solved problems will be handed over in written form for the absent student.
Reading material
- Obligatory literature
P. Atkins, J. de Paula: Physical Chemistry, 8th edition, Oxford University Press 2006, ISBN 9780198700722
- Literature developed by the Department
Physical Chemistry lecture
- Notes
Physical Chemistry lecture notes : http://kemia.ttk.pte.hu/fizkem/oktatas
- Recommended literature
P. Atkins, J. de Paula: Physical Chemistry, 8th edition, Oxford University Press 2006, ISBN 9780198700722
D. Freifelder: Physical Chemistry for Students of Biology and Chemistry, Science Books International Inc. ISBN 0 86720-002-2
Lectures
Practices
Seminars
1 The properties of gases: states of perfect gas, the gas laws, units.
Dr. Nagyné Dr. Zengő Lívia
2 Basic concepts in thermodynamics, expansion work, internal energy of a system. Application of the first law.
Dr. Nagyné Dr. Zengő Lívia
3 Calculation of enthalpy and calorimetry. Calculation of formation enthalpy and the heat capacity (cp, cv).
Dr. Nagyné Dr. Zengő Lívia
4 Calculation of the changes in internal energy.
Dr. Nagyné Dr. Zengő Lívia
5 Problem solving of entropy, changing of entropy in different processes.
Dr. Nagyné Dr. Zengő Lívia
6 Test: the gas laws, the first law, change in internal energy of a system, the heat capacities and entropy
Dr. Nagyné Dr. Zengő Lívia
7 Problems of the kinetic model of gases, collision with walls and surfaces.
Dr. Nagyné Dr. Zengő Lívia
8 Calculation: First and second rate chemical reactions.
Dr. Nagyné Dr. Zengő Lívia
9 Problem solving of second rate chemical reaction and enzyme reaction
Dr. Nagyné Dr. Zengő Lívia
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10 Electrochemical calculations: Faraday's laws, conductivity in electrolytes, Nernst equation, Galvan cells
Dr. Nagyné Dr. Zengő Lívia
11 Calculation of electrolysis and corrosion
Dr. Nagyné Dr. Zengő Lívia
12 Test: problems fom kinetic model of gases, reaction kinetics and Faraday’s laws.
Dr. Nagyné Dr. Zengő Lívia
Exam topics/questions
The solved problems will be handed over in written form for the students at the end of the semester.
Participants
Dr. Nagyné Dr. Zengő Lívia (EOQ0QG)
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72
OPE-KP2-T BASICS OF CHEMISTRY 2
Course director: DR. PÁL PERJÉSI, professor
Department of Pharmaceutical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – 40 Prerequisites: -
Topic
Based on the previously acquired high school knowledge the course provides an overview on the basic laws of Chemistry concentrating
on those that are ubiquitous in the chemistry-related subjects of the basic modules of the health related curriculums. The course helps
understanding the chemistry-related compulsory subjects of the modules.
Conditions for acceptance of the semester
Two midterm tests will be written during the semester on the 7th and the 12th weeks. The result of one of the tests should be above 60%.
The average of the two tests should be above 50%. One re-take chance is allowed. The result of the retake test is combined with the
previously written ones.
Mid-term exams
Two midterm tests will be written during the semester on the 7th and the 12th weeks. The result of one of the tests should be above 60%.
The average of the two tests should be above 50%. One re-take chance is allowed. The result of the retake test is combined with the
previously written ones.
Making up for missed classes
There is no opportunity to make up missed classes.
Reading material
- Obligatory literature
Ebbing D.D., Gammon S.D.: General Chemistry, Houghton Miffilin Co., Boston, 2009
- Literature developed by the Department
Almási A., Kuzma M., Perjési P.: General and Inorganic Chemistry - Laboratory Techniques and Practices, electronic educational
material University of Pécs, 2014
- Notes
- Recommended literature
en.wikibooks.org/wiki/General_Chemistry
J. McMurray, R. C. Fay: Chemistry, 5th edition
Lectures
1 The electronic structure of atom. Periodic properties.
Dr. Perjési Pál
2 The electronic structure of atom. Periodic properties.
Dr. Perjési Pál
3 Structure of molecules. The valence bond theory
Dr. Perjési Pál
4 Structure of molecules. The valence bond theory
Dr. Perjési Pál
5 Structure of molecules. The molecular-orbital theory.
Dr. Perjési Pál
6 Structure of molecules. The molecular-orbital theory.
Dr. Perjési Pál
7 Importance of inorganic compounds in living organisms.
Dr. Perjési Pál
8 Importance of inorganic compounds in living organisms.
Dr. Perjési Pál
9 Structure and reactions of oxygen. Mechanisms of oxygen activation.
Dr. Perjési Pál
10 Structure and reactions of oxygen. Mechanisms of oxygen activation.
Dr. Perjési Pál
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11 Sulfur: structure and reactivity.
Dr. Perjési Pál
12 Sulfur: structure and reactivity.
Dr. Perjési Pál
13 Nitrogen: structure and reactivity.
Dr. Perjési Pál
14 Nitrogen: structure and reactivity.
Dr. Perjési Pál
15 Phosphorous: structure and reactivity.
Dr. Perjési Pál
16 Phosphorous: structure and reactivity.
Dr. Perjési Pál
17 Carbon: structure and reactivity.
Dr. Perjési Pál
18 Carbon: structure and reactivity.
Dr. Perjési Pál
19 Silicon: structure and reactivity.
Dr. Perjési Pál
20 Silicon: structure and reactivity.
Dr. Perjési Pál
21 Boron and aluminium: structure and reactivity.
Dr. Perjési Pál
22 Boron and aluminium: structure and reactivity.
Dr. Perjési Pál
23 Coordination compounds I. The metal-ligand bonding.
Dr. Perjési Pál
24 Coordination compounds I. The metal-ligand bonding.
Dr. Perjési Pál
25 Coordination compounds II. Isomerism.
Dr. Perjési Pál
26 Coordination compounds II. Isomerism.
Dr. Perjési Pál
27 Coordination compounds III. Biochemical importance.
Dr. Perjési Pál
28 Coordination compounds III. Biochemical importance.
Dr. Perjési Pál
Practices
Seminars
Exam topics/questions
Written test covering the topics of the lectures.
Participants
Dr. Perjési Pál (F4H45V)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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74
OPE-QAS-T QUANTITATIVE ANALYTICAL CHEMISTRY CALCULATION
Course director: DR. GYŐZŐ KORNÉL KULCSÁR, assistant professor
Department of Pharmaceutical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – 50 Prerequisites: -
Topic
The Quantitative analytical chemistry calculation course helps students to understand the analytical (titrimetric) calculations. It makes
theoretical backgrounds more understandable.
Conditions for acceptance of the semester
According to the Code of Studies and Examinations (see on the homepage). During the semester maximum 3 missed classes are
acceptable. Two midterm tests will be written during the semester. The result of both tests should be above 60%.
Mid-term exams
Two written exams during the semester.
Making up for missed classes
Missing written exams should be made up.
Reading material
- Obligatory literature
Harris D.C.: Quantitative Chemical Analysis, 8th ed., W.H. Freeman and Co., New York, 2010
- Literature developed by the Department
Handouts.
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Introduction - Concentrations - Concentration of standard solutions.
Dr. Kulcsár Győző Kornél
2 Introduction - Concentrations - Concentration of standard solutions.
Dr. Kulcsár Győző Kornél
3 Acid-base titrations - Methods for calculating the titration results. Calculations with molarity and normality.
Dr. Kulcsár Győző Kornél
4 Acid-base titrations - Methods for calculating the titration results. Calculations with molarity and normality.
Dr. Kulcsár Győző Kornél
5 Neutralization analysis - Standardization of a titrant. Titration curve calculations.
Dr. Kulcsár Győző Kornél
6 Neutralization analysis - Standardization of a titrant. Titration curve calculations.
Dr. Kulcsár Győző Kornél
7 Calculation of pH in titration problems I. Hydrolysis of salts.
Dr. Kulcsár Győző Kornél
8 Calculation of pH in titration problems I. Hydrolysis of salts.
Dr. Kulcsár Győző Kornél
9 Calculation of pH in titration problems II. Buffers.
Dr. Kulcsár Győző Kornél
10 Calculation of pH in titration problems II. Buffers.
Dr. Kulcsár Győző Kornél
11 Non-aqueous titration calculations.
Dr. Kulcsár Győző Kornél
12 Non-aqueous titration calculations.
Dr. Kulcsár Győző Kornél
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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75
13 Complexometry - Methods for calculating the titration results.
Dr. Kulcsár Győző Kornél
14 Complexometry - Methods for calculating the titration results
Dr. Kulcsár Győző Kornél
15 Complex chemical equilibria - Calculations with the stability constants.
Dr. Kulcsár Győző Kornél
16 Complex chemical equilibria - Calculations with the stability constants.
Dr. Kulcsár Győző Kornél
17 Redox titrations II. - Calculations based on oxidimetry.
Dr. Kulcsár Győző Kornél
18 Redox titrations II. - Calculations based on oxidimetry.
Dr. Kulcsár Győző Kornél
19 Redox titrations I. - Redox titration curve calculations.
Dr. Kulcsár Győző Kornél
20 Redox titrations I. - Redox titration curve calculations.
Dr. Kulcsár Győző Kornél
21 Redox titrations I. - Calculations based on oxidimetry.
Dr. Kulcsár Győző Kornél
22 Redox titrations I. - Calculations based on oxidimetry.
Dr. Kulcsár Győző Kornél
23 Redox titrations III. - Calculations based on reductometry.
Dr. Kulcsár Győző Kornél
24 Redox titrations III. - Calculations based on reductometry.
Dr. Kulcsár Győző Kornél
25 Precipitate formation titrations - Calculations for the solubility products.
Dr. Kulcsár Győző Kornél
26 Precipitate formation titrations - Calculations for the solubility products.
Dr. Kulcsár Győző Kornél
27 Gravimetry.
Dr. Kulcsár Győző Kornél
28 Gravimetry.
Dr. Kulcsár Győző Kornél
Exam topics/questions
The final grade is established based on the average of each written exams.
Participants
Dr. Kulcsár Győző Kornél (R7V5ZT), Dr. Mészáros Petra (C705FN), Dr. Tyukodi Levente (IWJHJA)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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76
OPE-DRD-T DRUG DESIGN
Course director: DR. CSABA HETÉNYI, associate professor
Department of Pharmacology and Pharmacotherapy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 2
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 45 Prerequisites: -
Topic
The course offers an overview of the whole process of drug design between selection of the disease and marketing of the drug. The
introductory lectures are followed by detailed reviews of certain phases of drug design including prediction of both drug action and
pharmacokinetic properties. In this regard, theoretical and experimental methods of drug design will be also introduced. Case studies will
demonstrate successful examples and also difficulties arising during the design process. Students with a researcher attitude are primary
targets of this course. Besides them, the course provides useful knowledge for future medical doctors and pharmacists as it explains the
complex process of drug discovery in a comprehensible way. This hopefully helps the students navigating in the jungle of laws of
pharmacology also used in molecular design. Furthermore, the course deals with the problems of prediction of toxicity and side-effects,
and discusses certain questions of production and legalization process of new drugs, as well. In Journal Club sessions, recent research
articles will be featured with the students to deepen their knowledge in the areas discussed during the previous lectures. In this way, the
students can discover further connections themselves and make sure of the usefulness of their newly obtained knowledge in drug design.
Conditions for acceptance of the semester
Jelenleg a választható és elektív kurzusok esetén a szabályzat nem tartalmaz részvételi követelményt. Amennyiben szükséges itt valamit
megjelölnöm, akkor 25 %, de csak azért teszem, hogy kitölthető legyen az űrlap. Javasoltam a Tanulmányi Bizottság vezetőjének a
helyzet szabályzását és 50 % mértéket a hiányzásoknál.
Mid-term exams
There is a final test announced at the end of the semester. The test will include multiple choice questions or short essays. A mark is
offered according to the results of the written test or optionally by evaluation of the student's presentation prepared for the Journal Club.
The student can improve the mark according to university regulations.
Making up for missed classes
Replacement is possible according to personal consultation.
Reading material
- Obligatory literature
- Literature developed by the Department
The material of the course including pdfs of lectures and lists of questions will be made downloadable from the web site of the
Department of Pharmacology and Pharmacotherapy or a link will be provided during the lectures / in an e-mail.
- Notes
- Recommended literature
Patrick GL: An Introduction to Medicinal Chemistry, Oxford University Press
Lectures
1 Selection of the disease. Goals, terminology, trends.
Dr. Hetényi Csaba
2 Conditions. Strategies. Ligand-based design.
Dr. Hetényi Csaba
3 Traditional design.
Dr. Hetényi Csaba
4 Target-based drug design.
Dr. Hetényi Csaba
5 Target selection and validation.
Dr. Hetényi Csaba
6 Protein targets 1. General overview, structural proteins.
Dr. Hetényi Csaba
7 Protein targets 2. Enzymes and receptors.
Dr. Hetényi Csaba
8 Experimental structure determination methods.
Dr. Hetényi Csaba
9 Theoretical structure determination methods.
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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77
Dr. Hetényi Csaba
10 Lipids and nucleic acids as targets.
Dr. Hetényi Csaba
11 Journal club 1. Comparison of strategies
Dr. Hetényi Csaba
12 Journal club 2. Evaluation of targets
Dr. Hetényi Csaba
13 Experimental methods of lead selection and design.
Dr. Hetényi Csaba
14 Molecular complexes of leads. Thermodynamic and kinetic stability.
Dr. Hetényi Csaba
15 Theoretical methods of lead selection and design.
Dr. Hetényi Csaba
16 Lead optimizations, transformations.
Dr. Hetényi Csaba
17 ADMETox optimization 1. Goals, general description.
Dr. Hetényi Csaba
18 ADMETox optimization 2. Methods.
Dr. Hetényi Csaba
19 Termination of design. Production and development. Side-effects and postmarketing surveillance.
Dr. Hetényi Csaba
20 Case studies. The design of antiviral drugs.
Dr. Hetényi Csaba
21 Journal club 3. Development of new methods
Dr. Hetényi Csaba
22 Journal club 4. Paradigm shifts of drug design
Dr. Hetényi Csaba
23 Test
Dr. Hetényi Csaba
24 Test
Dr. Hetényi Csaba
Practices
Seminars
Exam topics/questions
Lists of questions will be provided at the end of each lecture specifying the required knowledge.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
78
OPE-ETI-T PHARMACY ETHICS
Course director: TIBOR SZOLCSÁNYI, assistant professor
Department of Behavioural Sciences [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 25 Prerequisites: -
Topic
The aim of the course is to help students gain sensitivity to the ethical issues connected to the pharmacy practice. During the course
students learn about the basic ethical principles governing the pharmacist-patient and the pharmacist-physician relationship. Students
also get acquainted with the dilemmas that are raised by the conflict between business and ethics in pharmacy. The most important
concerns of research ethics and some specific ethical issues, like the question of mind-enhancing drugs, are also discussed during the
course.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Written test taking place in the last class. To improve the grade, the test can be repeated two times in the first two weeks of the exam
period. Oral exam is also an option for that purpose.
Making up for missed classes
According to the Code of Studies and Examinations
Reading material
- Obligatory literature
--
- Literature developed by the Department
Additional materials: Neptun MeetStreet
- Notes
--
- Recommended literature
Robert Veatch and Amy Haddad (eds.): Case Studies in Pharmacy Ethics, 2nd edition, Oxford University Press, New York, 2008
Lectures
Practices
Seminars
1 Introduction
Dr. Szolcsányi Tibor
2 A short history of pharmacy
Dr. Szolcsányi Tibor
3 General ethical viewpoints
Dr. Szolcsányi Tibor
4 The principle of informed consent in modern health-care
Dr. Szolcsányi Tibor
5 The ethics of patient-pharmacist relationship
Dr. Szolcsányi Tibor
6 The ethics of physician-pharmacist relationship
Dr. Szolcsányi Tibor
7 The conflict between business and ethics in pharmacy
Dr. Szolcsányi Tibor
8 The placebo effect and its ethical concerns
Dr. Szolcsányi Tibor
9 Dietary supplements, performance- and mind- enhancing drugs
Dr. Szolcsányi Tibor
10 Ethical issues in clinical drug trials
Dr. Szolcsányi Tibor
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79
11 Summarizing discussion
Dr. Szolcsányi Tibor
12 Test
Dr. Szolcsányi Tibor
Exam topics/questions
--
Participants
Dr. Szolcsányi Tibor (HNQ526)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
80
OPE-GKT-T HISTORY OF MANUFACTURE OF MEDICINES
Course director: DR. SZILÁRD PÁL, assistant professor
Institute of Pharmaceutical Technology and Biopharmacy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – 100 Prerequisites: -
Topic
Aim of the course is to explain the importance of the birth of Pharmaceutical Technology, introducing the manufacture of medicines
from the ancient times until the new age. Lectures will explain how first medicines were made, how the first pharmaceutical technological
equipments were created and how the mass production of drugs became more and more important. Lectures will also elaborate the birth
of famous medicines, like the quinine, aspirin, insulin and the sildenafil.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
- participation on the lectures
- accepted work reports
- accepted written assessments
Students have to write an end-semester assessment from the lectures at acceptance level of 60%.
Making up for missed classes
Students must fulfil requirements determined by the Code of Studies and Examinations. Student has make up for the missed lectures and
work reports.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Leon Shargel, A. B.C. Yu, Stamford: Applied Biopharmaceutics and Pharmacokinetics
Susanna Wu-Pong, Yon Rojanasakul: Biopharmaceutical Drug Design and Development, Humana Press
Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel
Michael J. Rathbone, Michael S. Roberts: Modified-Release Drug Delivery Technology, Informa Healthcare
Michael E. Aulton: The Design and Manufacture of Medicines, Churchill Livingstone
Lectures
1 Introduction
Dr. Pál Szilárd
2 introduction
Dr. Pál Szilárd
3 Ancient technologies (Egypt, Greece, Persian Empire)
Dr. Pál Szilárd
4 Ancient technologies (Egypt, Greece, Persian Empire)
Dr. Pál Szilárd
5 Influence of alchemy to the pharmaceutical technology
Dr. Pál Szilárd
6 Influence of alchemy to the pharmaceutical technology
Dr. Pál Szilárd
7 Middle ages
Dr. Pál Szilárd
8 Middle ages
Dr. Pál Szilárd
9 Effect of industrial revolution
Dr. Pál Szilárd
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81
10 Effect of industrial revolution
Dr. Pál Szilárd
11 Development of medicines in the new age
Dr. Pál Szilárd
12 Development of medicines in the new age
Dr. Pál Szilárd
13 Birth of the first industrial manufacturers
Dr. Pál Szilárd
14 Birth of the first industrial manufacturers
Dr. Pál Szilárd
15 Evolution of community pharmacies
Dr. Pál Szilárd
16 Evolution of community pharmacies
Dr. Pál Szilárd
17 Drugs that changed the world
Dr. Pál Szilárd
18 Drugs that changed the world
Dr. Pál Szilárd
19 Invention of the quinine
Dr. Pál Szilárd
20 Invention of the aspirine
Dr. Pál Szilárd
21 Invention of various famous drugs
Dr. Pál Szilárd
22 Invention of the sildenafil
Dr. Pál Szilárd
23 Invention of the insulin
Dr. Pál Szilárd
24 Invention of the insulin
Dr. Pál Szilárd
25 Test
Dr. Pál Szilárd
26 Test
Dr. Pál Szilárd
27 Attending the Saracen Pharmacy in Pécs
Dr. Pál Szilárd
28 Attending the Saracen Pharmacy in Pécs
Dr. Pál Szilárd
Practices
Seminars
Exam topics/questions
Students can get the test topics in the institute or download the from website of the institute.
Participants
Dr. Kása Péter (ISWPRM), Dr. Pál Szilárd (FYF5E9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
82
OPE-BES-T BIOETHICS SEMINAR
Course director: DR: BEÁTA LAKI, assistant lecturer
Department of Behavioural Sciences [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 20 Prerequisites: -
Topic
This seminar can be a continuation of the basic Medical ethics course for those student who are interested in the topic more. This course
has the opportunity to examine further interesting and important fields of biomedical ethics which can broaden the view of students and
it can help to be more sensitive for these kind of questions in general.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Mid-term test.
Making up for missed classes
Theres is no possibility.
Reading material
- Obligatory literature
Course materials will be available through Neptun MeetStreet.
- Literature developed by the Department
Course materials will be available through Neptun MeetStreet.
- Notes
Course materials will be available through Neptun MeetStreet.
- Recommended literature
Course materials will be available through Neptun MeetStreet.
Lectures
Practices
Seminars
1 Bioethics
Dr. Laki Beáta
2 Theoretical introduction
Dr. Laki Beáta
3 Interpretation of basic concepts needed to discuss ethical issues 1.
Dr. Laki Beáta
4 Interpretation of basic concepts needed to discuss ethical issues
Dr. Laki Beáta
5 Interpretation of basic concepts needed to discuss ethical issues 2.
Dr. Laki Beáta
6 Interpretation of basic concepts needed to discuss ethical issues
Dr. Laki Beáta
7 Ethical dilemmas of reproductive medicine - movie
Dr. Laki Beáta
8 Ethical dilemmas of reproductive medicine - movie
Dr. Laki Beáta
9 Ethical dilemmas of reproductive medicine: gestational surrogate motherhood, IVF, stem cell research
Dr. Laki Beáta
10 Ethical dilemmas of reproductive medicine: gestational surrogate motherhood, IVF, stem cell research
Dr. Laki Beáta
11 Ethical issues of genetic interventions
Dr. Laki Beáta
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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83
12 Ethical issues of genetic interventions
Dr. Laki Beáta
13 Ethical issues of organ- and tissue transplantation
Dr. Laki Beáta
14 Ethical issues of organ- and tissue transplantation
Dr. Laki Beáta
15 Moral questions related to animal testing
Dr. Laki Beáta
16 Moral questions related to animal testing
Dr. Laki Beáta
17 Human experiments
Dr. Laki Beáta
18 Human experiments
Dr. Laki Beáta
19 Environmental Ethics 1.
Dr. Laki Beáta
20 Environmental Ethics
Dr. Laki Beáta
21 Environmental Ethics 2.
Dr. Laki Beáta
22 Environmental Ethics 2.
Dr. Laki Beáta
23 Summary of the semester
Dr. Laki Beáta
24 Written, test exam
Dr. Laki Beáta
Exam topics/questions
Course materials will be available through Neptun MeetStreet.
Participants
Dr. Laki Beáta (B0SCQX)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
84
OPE-JEA-T DISEASES OF SIGNAL TRANSDUCTION
Course director: DR. GYÖRGY SÉTÁLÓ, associate professor
Department of Medical Biology and Central Electron Microscope Laboratory [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OPO-GL1-T completed + OPO-G2B-T parallel
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
Topics of signal transduction will be discussed beyond the details of the compulsory course, Molecular cell biology 2. In 12 x 45 minutes
special attention is paid to mechanisms that are relevant to diseases.
The course is recommended to those students who are especially interested in the signaling aspects of pathological processes.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Two multiple-choice test-exams, with ~25 questions each, one halfway and another one at the end of the course.
Making up for missed classes
It is not possible to make up for missed classes.
Reading material
- Obligatory literature
- Literature developed by the Department
Lecturers using ppt will load these up onto the intranet after their class.
- Notes
- Recommended literature
Lectures
1 The protein kinase A system.
Dr. Sétáló György
2 Signaling in infectious diseases (cholera, pertussis and anthrax).
Dr. Palkovics Tamás
3 Growth factor signaling.
Dr. Sétáló György
4 Signaling through cell-cell and cell-matrix connections.
Dr. Sétáló György
5 First test.
Dr. Sétáló György
6 Stress signaling.
Dr. Bátor Judit
7 Signaling and inflammation.
Dr. Mikó Éva
8 Signaling of apoptosis.
Dr. Pap Marianna
9 Steroid signaling.
Dr. Sétáló György
10 Integrin signaling and metastasis.
Dr. Berta Gergely
11 Signaling gone wrong in the developing nervous system.
Dr. Ábrahám Hajnalka Gabriella
12 Second test.
Dr. Sétáló György
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Practices
Seminars
Exam topics/questions
Multiple-choice test questions based on the actually presented materials of the course.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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86
OPE-SP2-T PHARMACY BIOPHYSICS SEMINARS 2
Course director: ILDIKÓ PÉCSI, assistant professor
Department of Biophysics [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 2
Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours
Course headcount limitations (min.-max.): 5 – 100 Prerequisites: OPO-Z1E-T completed + OPO-Z2E-T parallel
Topic
The course is focusing on solving problems in order to have a deeper understanding of the theory.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
During the semester the student will have to write a test solving problems.
Making up for missed classes
Missed seminars cannot be made up
Reading material
- Obligatory literature
- Literature developed by the Department
Handouts and other online materials can be found on the departmental website (http://biofizika.aok.pte.hu)
- Notes
- Recommended literature
Damjanovich Sándor, Fidy Judit, Szöllősi János (eds.): Medical Biophysics, Medicina, Budapest, 2009
P.W. Atkins: Physical chemistry
Lectures
Practices
Seminars
1 Quantum mechanics 1
Dr. Lukács András Szilárd
2 Quantum mechanics 2
Dr. Lukács András Szilárd
3 Absorption spectroscopy
Dr. Lukács András Szilárd
4 Fluorescence spectroscopy 1
Takács-Kollár Veronika Tünde
5 Fluorescence spectroscopy 2
Pécsi Ildikó
6 Fluorescence spectroscopy 3
Dr. Ujfalusi Zoltán
7 Fast kinetic methods
Dr. Ujfalusi Zoltán
8 Thermodynamics. Recapitulation
Leipoldné Dr. Vig Andrea Teréz
9 Lasers
Dr. Lukács András Szilárd
10 Microscopy
Dr. Szabó-Meleg Edina
11 Mass Spectrometry
Dr. Talián Csaba Gábor
12 Test
Pécsi Ildikó
13 Infrared and FTIR spectroscopy
Dr. Lukács András Szilárd
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
87
14 Raman spectroscopy
Dr. Lukács András Szilárd
Exam topics/questions
http://biofizika.aok.pte.hu
Participants
Dr. Lukács András Szilárd (LZ2I4Q), Dr. Szabó-Meleg Edina (I0NKTU), Dr. Talián Csaba Gábor (RP9GGL), Dr. Ujfalusi Zoltán
(AZSO9Z), Leipoldné Dr. Vig Andrea Teréz (OL4J1R), Pécsi Ildikó (ED6HUG), Takács-Kollár Veronika Tünde (L5EB78)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
88
OPF-CY1-T CYBERNETICS FOR MEDICAL, DENTISTRY AND PHARMACY STUDENTS 1
Course director: LÁSZLÓ ZOLTÁN PÉCZELY, assistant professor
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 30 Prerequisites: -
Topic
Cybernetics embracing more disciplines deals with the control, regulation, information flow and processing occuring in expediently
working dinamical systems. The most important goal of our subject is to help the students understand the functional principles of the
regulatory systems, mainly those of the human body. Furthermore, we would like to familiarize the students with how the balance of the
regulatory systems can be maintained by their wide adaptive and learning capacity/capability. We would like to demonstrate that etiology
of many diseases can be explained by the disruption of balance, how the balance can be restored by the therapy and, at the same time,
how the therapy can cause the shift of the balance in other parts of the system (side effect). In addition to the biological systems, both
the functional description of the artificial regulatory systems and the artificial intelligence will be addressed. In the first semester the
following topics are discussed: general description of systems, mathematical basics, the concept of homeostasis, biocybernetics of cellular
and subcellular stuctures, mathematical model of the blood coagulation cascade, cardiorespiratoric system as regulatory system,
neuroendocrine regulation.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Writing of case study, online test.
Making up for missed classes
Not necessary, but it is possible in another language
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Guyton & Hall: Textbook of Medical Physiology
V. V. Purin, R. M. Buyevskiy: Introduction To Medical Cybernetics
Peter Norvig, Stuart J. Russell: MI modern megközelítésben
James Kneer, James Sneyd: Mathematical Physiology I.: Cellular Physiology
James Kneer, James Sneyd: Mathematical Physiology II.: System Physiology
Lectures
1 Introduction: Cybernetics as discipline, definition of systems, general description. Relationship between system and enviroment.
Living organisms as cybernetic systems. Doctor and patient as the elements of cybernetic system.
Dr. Péczely László Zoltán
2 The concept of information, collecting and storing information, information analysis. Measurement techniques and intervention
issues.
Dr. Péczely László Zoltán
3 Mathematical tools in Cybernetics I
Dr. Péczely László Zoltán
4 Mathematical tools in Cybernetics II
Dr. Péczely László Zoltán
5 Model and reality, deductive and inductive inference, modelling.
Dr. Péczely László Zoltán
6 Homeostasis. Hierarchical structure of the regulation of organism. Role of feedback in regulatory systems.
Dr. Péczely László Zoltán
7 Biocybernetics of cellular and subcellular stuctures, analogies (modelling of membrane processes, integrative description and
models of transductional pathways).
Dr. Péczely László Zoltán
8 Mathematical modelling of the blood coagulation cascade.
Dr. Péczely László Zoltán
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9 Integrative cardiorespiratoric regulation, regulatory disturbances, options for interventions I
Dr. Péczely László Zoltán
10 Integrative cardiorespiratoric regulation, regulatory disturbances, options for interventions II
Dr. Péczely László Zoltán
11 Integrative neuroendocrine regulation, regulatory disturbances, options for interventions I
Dr. Péczely László Zoltán
12 Integrative neuroendocrine regulation, regulatory disturbances, options for interventions II
Dr. Péczely László Zoltán
Practices
Seminars
Exam topics/questions
The topics of the lectures
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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90
OPF-EBK-T FOOD SAFETY AND CRISIS SITUATIONS
Course director: DR. TÍMEA VARJAS, assistant professor
Department of Public Health Medicine [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 4 – 30 Prerequisites: -
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
Although food legislation and legal background is strict in EU some food safety crises and emergencies occur we can hear just a few
word in the media about. This course „pulls the veil” of the background, causes and concealed information of food safety crises. Topics
are about the most interesting and important information of these situations.
Conditions for acceptance of the semester
Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied.
Mid-term exams
Examination: written test
Making up for missed classes
based on individual consideration
Reading material
- Obligatory literature
- Literature developed by the Department
PPT-presentations (Neptun)
- Notes
- Recommended literature
Lectures
1 Introduction
Dr. Raposa László Bence
2 European and Hungarian food safety regulation
Dr. Raposa László Bence
3 Cases and concealed facts I. (Historical overview)
Dr. Raposa László Bence
4 Cases and concealed facts II.
Dr. Raposa László Bence
5 Crisis management and communication I.
Dr. Raposa László Bence
6 Crisis management and communication II.
Dr. Raposa László Bence
7 Food industry "tricks": Changes which the layman does not realize
Dr. Raposa László Bence
8 Food industry "tricks": Changes which the layman does not realize
Dr. Raposa László Bence
9 Actual food safety crisis
Dr. Raposa László Bence
10 Actual food safety crisis
Dr. Raposa László Bence
11 Summary
Dr. Raposa László Bence
12 Exam
Dr. Raposa László Bence
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Practices
Seminars
Exam topics/questions
Neptun
Participants
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92
OPF-H3A-T MEDICAL HUNGARIAN 3A - BASICS OF MEDICAL COMMUNICATION FOR STUDENTS OF
PHARMACY
Course director: GABRIELLA NAGY, assistant lecturer
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OPF-H2A-T completed + OPF-H3B-T parallel
Topic
This course in devoted to the acquisition of language and communicative functions of the basic history taking process and the description
of medications.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Making up for missed classes
In the case of absences up to 25% of total class time, oral examination will have to be taken.
Reading material
- Obligatory literature
- Literature developed by the Department
Mária Győrffy: English for Doctors, Idióma Bt. Pécs, 2001 - can be purchased in the Department
- Notes
- Recommended literature
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng
Lectures
Practices
Seminars
1 Family History, social history and previous diseases
2 Family History, social history and previous diseases
3 Complaint and Pain
4 Complaint and Pain
5 Headache, dizziness
6 Perspiration, nausea, vomiting
7 Vision, shortness of breath, cough-Listening comprehension and speaking skills
8 Stool, urine
9 Stool, urine
10 Heart complaints, appetite
11 Shivering, fever, oedema
12 Frequent diseases
13 Oesophagus, stomach, gallbladder
14 Bowel diseases, cardiovascular diseases
15 Forms of medications
16 Test 1
17 Types of medications
18 Types of medications
19 Instructions concerning the application of medications: oral medications
20 Instructions concerning the application of medications: oral medications
21 Instructions concerning the application of medications: drops
22 Instructions concerning the application of medications: creams and ointments
23 Prescriptions
24 Test 2.
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Exam topics/questions
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Ronczykné Berta Anikó (CJZOFU), Szalai-Szolcsányi Judit
(RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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94
OPF-H3B-T MEDICAL HUNGARIAN 3B - MEDICAL COMMUNICATION IN PRACTICE FOR STUDENTS OF
PHARMACY
Course director: GABRIELLA NAGY, assistant lecturer
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OPF-H2B-T completed + OPF-H3A-T parallel
Topic
This course serves the skills development based on language and communicative functions acquired in course 3A.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Making up for missed classes
In the case of absences up to 25% of total class time, oral examination will have to be taken.
Reading material
- Obligatory literature
- Literature developed by the Department
Mária Győrffy: English for Doctors, Idióma Bt. Pécs, 2001 - can be purchased in the Department
- Notes
- Recommended literature
--
Lectures
Practices
Seminars
1 Family History, social history and previous diseases - Listening comprehension and speaking skills
2 Family History, social history and previous diseases - Listening comprehension and speaking skills
3 Complaint and Pain - Listening comprehension and speaking skills
4 Complaint and Pain - Listening comprehension and speaking skills
5 Headache, dizziness - Listening comprehension and speaking skills
6 Perspiration, nausea, vomiting - Listening comprehension and speaking skills
7 Vision, shortness of breath, cough - Listening comprehension and speaking skills
8 Stool, urine - Listening comprehension and speaking skills
9 Stool, urine - Listening comprehension and speaking skills
10 Heart complaints, appetite - Listening comprehension and speaking skills
11 Shivering, fever, oedema - Listening comprehension and speaking skills
12 Frequent diseases - Listening comprehension and speaking skills
13 Oesophagus, stomach, gallbladder - Listening comprehension and speaking skills
14 Bowel diseases, cardiovascular diseases - Listening comprehension and speaking skills
15 Forms of medications - Listening comprehension and speaking skills
16 Test 1
17 Types of medications - Listening comprehension and speaking skills
18 Types of medications - Listening comprehension and speaking skills
19 Instructions concerning the application of medications: oral medications - Listening comprehension and speaking skills
20 Instructions concerning the application of medications: oral medications - Listening comprehension and speaking skills
21 Instructions concerning the application of medications: drops - Listening comprehension and speaking skills
22 Instructions concerning the application of medications: creams and ointments - Listening comprehension and speaking skills
23 Prescriptions - Listening comprehension and speaking skills
24 Consolidation, Test 2.
Exam topics/questions
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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95
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Ronczykné Berta Anikó (CJZOFU), Szalai-Szolcsányi Judit
(RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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96
OPF-HB1-T HOW TO ACHIEVE BETTER GRADE IN ORGANIC CHEMISTRY 1
Course director: DR. BALÁZS BOGNÁR, assistant professor
Department of Organic and Pharmacological Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 0 practices + 10 seminars = total of 10 hours
Course headcount limitations (min.-max.): 2 – 20 Prerequisites: OPA-GC1-T completed + OPA-S1E-T parallel
Topic
The aim of the course is to help the students to understand the important reaction mechanisms, and find the connections between the
different topics.
1. Reaction mechanisms in organic chemistry
2. Projection structures, radical substitution
3. Electrophilic addition
4. Electrophilic aromatic substitution
5. Nucleophilic substitution 1, alkyl halides
6. 1. test
7. Nucleophilic substitution 2, organometallics, alcohols, phenols, ethers.
8. Aromatic nucleophilic substitutions
9. Stereochemistry
10. 2. test
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Nincs.
Making up for missed classes
Nincs
Reading material
- Obligatory literature
- Literature developed by the Department
The worksheets will be handed on the seminar.
- Notes
- Recommended literature
Estelle K. Meislich; Herbert Meislich; Jacob Sharefkin: Schaum’s Series 3000 Solved Problems In Organic Chemistry, McGraw-
Hill, Inc., New York, 1994
T. W. Graham Solomons: Organic Chemistry, 7th edition, Wiley and Sons, New York, 2000
John McMurry, Eric Simanek: Fundamentals of Organic Chemistry, 6th edition, Thomson Brooks/Cole, Belmont, 2007
Lectures
Practices
Seminars
1 Reaction mechanisms in organic chemistry.
Dr. Bognár Balázs
2 Projection structures, radical substitutions and nomenclature of alkanes.
Dr. Bognár Balázs
3 Reaction of alkenes and alkynes: electrophilic addition, oxidations.
Dr. Bognár Balázs
4 Aromaticity, electrophilic aromatic substitution: mechanism, examples.
Dr. Bognár Balázs
5 Nucleophilic substitutions of alkyl halides.
Dr. Bognár Balázs
6 1. test (alkanes, alkenes, alkynes, aromatics, organohalides).
Dr. Bognár Balázs
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97
7 Nucleophilic substitution 2: synthesis and reactions organometallics, alcohols, phenols, ethers.
Dr. Bognár Balázs
8 Aromatic nucleophilic substitutions of carbocycles.
Dr. Bognár Balázs
9 Stereochemistry: classification of isomerism, absolut configuration.
Dr. Bognár Balázs
10 2. test: alcohols, phenols, ethers, organometallics, isomerism.
Dr. Bognár Balázs
Exam topics/questions
There is no exam.
Participants
Dr. Bognár Balázs (U34DM4)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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98
OPF-IPM-T INNOVATION AND PROJECT MANAGEMENT FROM A BUSINESS PERSPECTIVE (KÜLÖN
KURZUS!!!)
Course director: DR. RITA BOGNÁR, research associate professor
Department of Biochemistry and Medical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 24 Prerequisites: -
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
The main objective of the innovation and project management course is to develop the business orientation skills of the students, while
deepening their knowledge in project management theory, methods and practice. Participants will have the capability how to develop
innovative projects for business.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Home work tasks in Moodle during the semester. At the end of the course final essay or final written test according to public health
situation.
Making up for missed classes
No way.
Reading material
- Obligatory literature
Not relevant.
- Literature developed by the Department
Lectures in pdf form will be available on Neptun Meet Street.
- Notes
Not relevant.
- Recommended literature
1. Joseph W. Weiss, Robert K. Wysocki (1992): 5-Phase Project Management: A Practical Planning & Implementation Guide,
Addison-Wesley
2. John Hauser, Gerard J. Tellis and Abbie Griffin: A Review and Agenda for „Marketing Science”, Marketing Science, Vol. 25, No.
6, 25th Anniversary Issue (Nov. - Dec., 2006), pp. 687-717
3. Barbara J. Gabrys, Jane A. Langdale (2012): How to succeed as a scientist, From Postdoc to Professor, Cambridge University
Press, New York, pp.45-57.
Lectures
1 Basics of project management (definition, objectives)
Dr. Bognár Rita
2 Global business overview
Dr. Bognár Rita
3 Project life cycle
Dr. Bognár Rita
4 Different type of business organization
Dr. Bognár Rita
5 Project initialisation (structure, work packages)
Dr. Bognár Rita
6 Leadership of a project
Dr. Bognár Rita
7 Human resource management (team building, teamwork)
Dr. Bognár Rita
8 Project planning 1. (time, resources)
Dr. Bognár Rita
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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99
9 Project planning 2. (cost, risk, communication)
Dr. Bognár Rita
10 Project network
Dr. Bognár Rita
11 Project communication tools
Dr. Bognár Rita
12 Project protocol
Dr. Bognár Rita
13 Financial management 1. (Main budget categories)
Dr. Bognár Rita
14 Financial management 2.
Dr. Bognár Rita
15 Procurement management
Dr. Bognár Rita
16 Contracts
Dr. Bognár Rita
17 Risk management
Dr. Bognár Rita
18 Conflict management
Dr. Bognár Rita
19 Project controlling and monitoring
Dr. Bognár Rita
20 Project reporting
Dr. Bognár Rita
21 Project closing
Dr. Bognár Rita
22 Project maintenance
Dr. Bognár Rita
23 Innovation management 1.(Intellectual properties)
Dr. Bognár Rita
24 Innovation management 2. (Patent)
Dr. Bognár Rita
Practices
Seminars
Exam topics/questions
Neptun Meet Street
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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100
OPF-MGE-T MOLECULAR GERONTOLOGY
Course director: DR. KRISZTIÁN KVELL, associate professor
Department of Pharmaceutical Biotechnology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 3 – 200 Prerequisites: OPE-MS1-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
The curriculum covers physiological aspects of ageing and the molecular background of the ageing process, at cell, intracellular signaling
and nucleic acid level. It highlights the potential molecular intervention possibilities to slow down the ageing process and decrease
development of age related diseases.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Writing test
Making up for missed classes
None
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
www.medbiotech.com
- Recommended literature
Lectures
1 Basic Knowledge in Gerontology
Dr. Kvell Krisztián
2 Aging Theories
Dr. Kvell Krisztián
3 Mitochondrial Aging
Dr. Kvell Krisztián
4 Aging and Gene Expression
Dr. Kvell Krisztián
5 Genetic Background of Longevity
Dr. Kvell Krisztián
6 Alterations of the Genome due to Aging, Senescence and Cancer
Dr. Kvell Krisztián
7 Cellular Effects of Acute and Chronic Stress
Dr. Kvell Krisztián
8 Metabolism and Longevity I
Dr. Kvell Krisztián
9 Metabolism and Longevity II
Dr. Kvell Krisztián
10 Senescence-related Intracellular Pathologies
Dr. Kvell Krisztián
11 Senescence-related Intracellular Pathologies
Dr. Kvell Krisztián
12 Molecular Mechanisms of Interventions
Dr. Kvell Krisztián
13 Invited Lecturer I
Dr. Kvell Krisztián
14 Invited Lecturer II
Dr. Kvell Krisztián
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101
Practices
Seminars
Exam topics/questions
MeetStreet
www.medbiotech.com
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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102
OPF-SNA-T CARBON NANOSTRUCTURES
Course director: DR. BEÁTA LEMLI, assistant professor
Department of Organic and Pharmacological Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 3
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 2 – 20 Prerequisites: OPA-ALK-T completed
Topic
Carbon is an indispensable element of life, thanks to the ability to form different chemical bonds with most elements of the periodic
table, enabling the creation of different and complex life forms. The discovery of the organic carbon compounds has been started in the
19th century, and now they are the part of our lives. Nowadays the previously discovered allotropes of carbon - fullerenes, carbon
nanotubes, graphenes, graphene nanoribbons - are in the focus, however, their real wide application still seems to be a big challenge and
needs further investigations. During this curse, students will be introduced to the promising pharmaceutical chemistry, medical and
biological applications of these materials and to the latest results of related research.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
One written exam during the semester, the acceptance level is 60%. One oral presentation by students.
Making up for missed classes
There is no possibility to make up for a missed lecture and practice
Reading material
- Obligatory literature
Physical Biochemistry: Applications to Biochemistry and Molecular Biology (Life Sciences/Biochemistry) by David M. Freifelder,
2nd Edition, ISBN-13: 978-0716714446, ISBN-10: 0716714442
- Literature developed by the Department
The slides of the lectures are electronically available.
- Notes
- Recommended literature
Physical Biochemistry: Applications to Biochemistry and Molecular Biology (Life Sciences/Biochemistry) by David M. Freifelder,
2nd Edition, ISBN-13: 978-0716714446, ISBN-10: 0716714442
Lectures
1 Introduction of the course requirements. Fullerenes, carbon nanostructure, graphene: their discovery, historical review
Dr. Lemli Beáta
2 Fullerenes, carbon nanostructure, graphene: their discovery, historical review
Dr. Lemli Beáta
3 Preparation, synthesis, general properties
Dr. Lemli Beáta
4 Preparation, synthesis, general properties
Dr. Lemli Beáta
5 Covalent and non-covalent functionalization of carbon nanomaterials
Dr. Lemli Beáta
6 Covalent and non-covalent functionalization of carbon nanomaterials
Dr. Lemli Beáta
7 Nanotechnology in wastewater treatment
Dr. Lemli Beáta
8 Nanotechnology in wastewater treatment
Dr. Lemli Beáta
9 Carbon nanostructures and DNA
Dr. Lemli Beáta
10 Carbon nanostructures and DNA
Dr. Lemli Beáta
11 Cellular uptake
Dr. Lemli Beáta
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103
12 Cellular uptake
Dr. Lemli Beáta
13 Biodistribution
Dr. Lemli Beáta
14 Biodistribution
Dr. Lemli Beáta
15 Cancer diagnosis and treatment
Dr. Lemli Beáta
16 Cancer diagnosis and treatment
Dr. Lemli Beáta
17 Toxicity
Dr. Lemli Beáta
18 Toxicity
Dr. Lemli Beáta
19 Student’s lecture.
Dr. Lemli Beáta
20 Student’s lecture.
Dr. Lemli Beáta
21 Written test.
Dr. Lemli Beáta
22 Written test.
Dr. Lemli Beáta
23 Summary and conclusions
Dr. Lemli Beáta
24 Summary and conclusions
Dr. Lemli Beáta
Practices
Seminars
Exam topics/questions
The topics of the written test are similar to the topics of the lectures.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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104
OPF-SSG-T HISTOLOGY SEMINAR FOR PHARMACY STUDENTS
Course director: DR. BALÁZS OPPER, assistant professor
Department of Anatomy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OPO-AI2-T parallel
Topic
The aim of the subject is to complete the knowledge about structure of organ systems. Besides gross anatomy and basic histological
knowledge presented in mandatory anatomy courses, the ‘Histology seminars for pharmacy students’ offers better understanding of
histological background of physiological and oathophysiological processes and conditions.
Conditions for acceptance of the semester
The semester can not be accepted over 2 absences.
Mid-term exams
Multimedia test on last seminar.
Making up for missed classes
Not possible.
Reading material
- Obligatory literature
- Literature developed by the Department
http://an-server.pote.hu
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Histology of the skin I.
Szabó Edina Ivett
2 Histology of the skin II.
Szabó Edina Ivett
3 Histology of the gastrointestinal tract I.
Szabó Edina Ivett
4 Histology of the gastrointestinal tract II.
Szabó Edina Ivett
5 Histology of the gastrointestinal tract III.
Szabó Edina Ivett
6 Histology of the gastrointestinal tract IV.
Szabó Edina Ivett
7 Histology of the gastrointestinal tract V.
Szabó Edina Ivett
8 Histology of the gastrointestinal tract VI.
Szabó Edina Ivett
9 Histology of the kidney
Szabó Edina Ivett
10 Respiratory system.
Szabó Edina Ivett
11 Histology of the male genitalia I.
Szabó Edina Ivett
12 Histology of the male genitalia II.
Szabó Edina Ivett
13 Histology of the female genitalia I.
Szabó Edina Ivett
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105
14 Histology of the female genitalia II.
Szabó Edina Ivett
15 Histology of the female genitalia III.
Szabó Edina Ivett
16 Histology of the female genitalia IV.
Szabó Edina Ivett
17 Endocrine organs I.
Szabó Edina Ivett
18 Endocrine organs II.
Szabó Edina Ivett
19 Histology of the peripheral nervous system i.
Szabó Edina Ivett
20 Histology of the peripheral nervous system II.
Szabó Edina Ivett
21 Eyebulb I.
Szabó Edina Ivett
22 Eyebulb II.
Szabó Edina Ivett
23 Test
Szabó Edina Ivett
24 Test
Szabó Edina Ivett
Exam topics/questions
http://an-server.pote.hu
Participants
Dr. Füredi Nóra Judit (WD29KK), Dr. Gaszner Tamás (YX6IQ5), Dr. Jüngling Adél (HB0TWF), Dr. Pham Dániel (G6T2FO), Szabó
Edina Ivett (CQY1BL)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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106
OPF-TG1-T STUDENT PROJECT RESEARCH FOR STUDENTS OF PHARMACEUTIST PROGRAMME 1
Course director: DR. GYÖRGYI HORVÁTH, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: -
Topic
The course aims at promoting of students to make student research projects on the field of pharmaceutical sciences. Furthermore, we
wish to give individual possibilities of students to perform experiments in the different pharmaceutical institutes involved into Students
Research Society.
Conditions for acceptance of the semester
The continuous student’s work is recommended. The continuous enrollment of consecutive courses can be stopped and continued in
further semesters.
The prerequisite of this course (TDK 1): registration of the student in the database of Students’ Research Society.
Mid-term exams
TG1
- Topic plan of student’s research project with the confirmation of supervisor
- Introduction of scientific articles found by the student in databases
- The topic plan and articles must be sent for course supervisor at the end of 13th week of the semester.
Making up for missed classes
There is no possibility.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
ScienceDirect database
Lectures
Practices
Seminars
Exam topics/questions
Not applicable.
Participants
Dr. Horváth Györgyi (GDLTCH), Dr. Poór Miklós (ARWF5Z), Dr. Vida Róbert György (BN08GS)
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107
OPF-TMB-T MOLECULAR BIOLOGY OF TUMORS
Course director: DR. EDINA PANDUR, assistant professor
Department of Pharmaceutical Biology [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 30 Prerequisites: OPO-GL1-T completed + OPO-G2B-T completed
Topic
During the course we will discuss the molecular mechanisms of tumor development. We will deal with characteristic features of tumor
cells, and cancers. The function of influencing factors, risk factors, causes, the underlying molecular mechanisms, e.g. mutations, the
role of oncogenes and tumor-suppressor genes, DNA repair, epigenetics and the role of immune system will be discussed in detail. We
will emphasize the function of cell signaling pathways and the failure of apoptosis in tumorigenesis. We will speak about the molecular
mechanisms of invasion and metastasis of tumors, the genes and proteins which have a crucial role in these processes. The participants
will get an insight into the molecular diagnosis, genetic aberrations, and molecular alterations of human cancers. We will discuss the
possibilities for cancer therapies, the new approaches such as gene therapy and immunotherapy.
Conditions for acceptance of the semester
Max. 3 absences
Mid-term exams
One assay, one midterm exam.
Making up for missed classes
Personal consultation
Reading material
- Obligatory literature
- Literature developed by the Department
Educational materials will be uploaded to Neptun MeetStreet.
- Notes
- Recommended literature
Lauren Pecorino: Molecular Biology of Cancer
Wolfgang Arthur Schulz: Molecular Biology of Human Cancers
Lectures
1 Introduction to cancers: classification and characterization of cancers, causes of cancer, properties of cancer cells, principles of
therapies, targets of therapies
Dr. Pandur Edina
2 Introduction to cancers: classification and characterization of cancers, causes of cancer, properties of cancer cells, principles of
therapies, targets of therapies
Dr. Pandur Edina
3 Tumor genetics: mutations, carcinogenic agents, inheritance, tumor genes, defects in DNA repair and predispositions to cancer,
cell protection mechanisms
Dr. Pandur Edina
4 Tumor genetics: mutations, carcinogenic agents, inheritance, tumor genes, defects in DNA repair and predispositions to cancer,
cell protection mechanisms
Dr. Pandur Edina
5 Tumor epigenetics: mechanisms of epigenetic inheritance, imprinting, DNA methylation, epigenetics of cell differentiation and
tissue homeostasis
Jánosa Gergely
6 Tumor epigenetics: mechanisms of epigenetic inheritance, imprinting, DNA methylation, epigenetics of cell differentiation and
tissue homeostasis
Jánosa Gergely
7 Oncogenes and tumor-suppressor genes
Dr. Pandur Edina
8 Oncogenes and tumor-suppressor genes
Dr. Pandur Edina
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108
9 The cell cycle, apoptosis and senescence: checkpoints, therapeutic targets and inhibitors, molecular mechanisms of apoptosis,
replicative senescence and its disturbances in human cancers
Pap Ramóna
10 The cell cycle, apoptosis and senescence: checkpoints, therapeutic targets and inhibitors, molecular mechanisms of apoptosis,
replicative senescence and its disturbances in human cancers
Pap Ramóna
11 Signaling pathways in tumors: MAPK, PI3K, TP53 network, NFkappaB, TGFbeta, STAT signaling
Dr. Pandur Edina
12 Signaling pathways in tumors: MAPK, PI3K, TP53 network, NFkappaB, TGFbeta, STAT signaling
Dr. Pandur Edina
13 Invasion and metastasis: genes and proteins involved in cell-to-cell, cell-matrix adhesion, in extracellular matrix remodeling
during tumor invasion; angiogenesis.
Dr. Pandur Edina
14 Invasion and metastasis: genes and proteins involved in cell-to-cell, cell-matrix adhesion, in extracellular matrix remodeling
during tumor invasion; angiogenesis.
Dr. Pandur Edina
15 The role of immune system in tumors: inflammation, infections, cancer vaccines, inhibition of the immune system
Pap Ramóna
16 The role of immune system in tumors: inflammation, infections, cancer vaccines, inhibition of the immune system
Pap Ramóna
17 Stem cells and cancer: Wnt signaling, Hh signaling, differentiation therapy
Dr. Pandur Edina
18 Stem cells and cancer: Wnt signaling, Hh signaling, differentiation therapy
Dr. Pandur Edina
19 Cancer prevention: nutrients, energy metabolism of tumors, hormones and gene interactions
Pap Ramóna
20 Cancer prevention: nutrients, energy metabolism of tumors, hormones and gene interactions
Pap Ramóna
21 Diagnosis of tumors: molecular diagnosis, molecular detection and classification
Jánosa Gergely
22 Diagnosis of tumors: molecular diagnosis, molecular detection and classification
Jánosa Gergely
23 Human cancers I: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers
Dr. Tóth Dénes
24 Human cancers I: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers
Dr. Tóth Dénes
25 Human cancers II: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers
Dr. Tóth Dénes
26 Human cancers II: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers
Dr. Tóth Dénes
27 Drugs in cancer therapy: molecular mechanisms of cancer chemotherapy, targeted drug therapy, immunotherapy, gene therapy
Dr. Fliszár-Nyúl Eszter
28 Drugs in cancer therapy: molecular mechanisms of cancer chemotherapy, targeted drug therapy, immunotherapy, gene therapy
Dr. Fliszár-Nyúl Eszter
Practices
Seminars
Exam topics/questions
Simple choice test based on the lectures.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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109
OPE-DM1-T DEMONSTRATOR ACTIVITY 1
Course director: DR. LÁSZLÓ JÓZSEF CZOPF, associate professor
1st Department of Internal Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ both semesters ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 300 Prerequisites: -
Topic
This course gives support and acknowledgement for students performing documented and successful supervised teaching activities and
taking an active part in organizing courses.
The subjects can be taken up in eight semesters (in a total value of 16 credits).
Conditions for acceptance of the semester
Students have to register every semester as demonstrators, should provide proof of previous demonstrator activity, and the semester will
be signed on the basis of at least 24 hours of teaching or organizatory activity. The grades will be given according to the Code of
Demonstrators with additional requirements, that you can reach using the following links: Code of Demonstrator Students:
https://docs.google.com/document/d/1xkkyeRdZcDphnqWEkpON0SQf34MpBBJqogG09foI8Rw/edit?usp=sharing
Faculty Home Page of the Circle of Demonstrator Students (DDK):
http://aok.pte.hu/en/egyseg/almenu/980/339
Mid-term exams
At least two midsemester tests should be successfully completed to pass.
Making up for missed classes
There are no absences accepted from the 24 hours demonstrator activity.
Reading material
- Obligatory literature
- Literature developed by the Department
..
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
The topics of the tests depend on the specific course of the demonstrator activity.
Participants
Dr. Czopf László József (BAVD1M), Dr. Koppán Ágnes Judit (ZAEQDO), Dr. Sebők Judit (GLM10L), Dr. Tamás Andrea (F7QM8G),
Dr. Ujvári Balázs (EN1LY9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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110
OPE-WMI-T WEAK MOLECULAR INTERACTIONS
Course director: DR. SÁNDOR KUNSÁGI-MÁTÉ, associate professor
Department of Organic and Pharmacological Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ both semesters ▪ recommended semester: 3
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 2 – 12 Prerequisites: OPA-GC1-T completed
Topic
The complex biochemical equilibria in living bodies as reversible chemical reactions are based on a series of weak molecular interactions.
Those interactions are playing very important role in the transfers of such bioactive molecules like the drugs and toxins. Further to this,
the weak molecular interactions also play important role in the molecular packing, molecular formulation of medicines. The weak
character of these interactions resulted that both the molecular environment and the temperature has high impact on these interactions.
The temperature itself affects the efficiency of drugs through affecting the transfer and the drug – target interactions. Therefore detailed
description of the temperature dependence of weak interactions is very important also in the associated therapies. Students will become
acquainted through several newest research results with the pharmaceutical applications of the processes listed above and with the
associated measuring methods and equipments.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
One written exam during the semester, the acceptance level is 60%.
Making up for missed classes
There is no possibility to make up for a missed lecture and practice
Reading material
- Obligatory literature
David Freifelder: Physical Biochemistry
- Literature developed by the Department
Slides and notes of all lectures are available electronically. All topics discussed will be associated with papers published recently.
Those papers together with the related doctoral dissertations in English will also be offered to support the teaching.
- Notes
- Recommended literature
Atkins: Physical Chemistry I-III.
David Freifelder: Physical Biochemistry
Lectures
1 Types of molecular interactions.
Dr. Kunsági-Máté Sándor
2 Types of molecular interactions.
Dr. Kunsági-Máté Sándor
3 Chemical equilibrium based on the weak molecular interactions.
Dr. Kunsági-Máté Sándor
4 Chemical equilibrium based on the weak molecular interactions.
Dr. Kunsági-Máté Sándor
5 Determination of the chemical equilibrium and the stoichiometry of the complexes.
Dr. Kunsági-Máté Sándor
6 Determination of the chemical equilibrium and the stoichiometry of the complexes.
Dr. Kunsági-Máté Sándor
7 Correlation between the chemical equilibrium and the free enthalpy.
Dr. Kunsági-Máté Sándor
8 Correlation between the chemical equilibrium and the free enthalpy.
Dr. Kunsági-Máté Sándor
9 Investigation of the weak interaction by measuring the fluorescence.
Dr. Kunsági-Máté Sándor
10 Investigation of the weak interaction by measuring the fluorescence.
Dr. Kunsági-Máté Sándor
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111
11 Application of the Job’s method in the fluorescence measurements.
Dr. Kunsági-Máté Sándor
12 Application of the Job’s method in the fluorescence measurements.
Dr. Kunsági-Máté Sándor
13 Direct measuring the interaction enthalpy by differential scanning calorimetry.
Dr. Kunsági-Máté Sándor
14 Direct measuring the interaction enthalpy by differential scanning calorimetry.
Dr. Kunsági-Máté Sándor
15 Interactions of aromatic compounds. Interactions of bioactive compounds with DNA.
Dr. Kunsági-Máté Sándor
16 Interactions of aromatic compounds. Interactions of bioactive compounds with DNA.
Dr. Kunsági-Máté Sándor
17 Investigations of model-systems: interactions of calixarenes with phenols and fullerenes.
Dr. Kunsági-Máté Sándor
18 Investigations of model-systems: interactions of calixarenes with phenols and fullerenes.
Dr. Kunsági-Máté Sándor
19 Investigations of the conformation changes of proteins by fluorescence and calorimetric methods.
Dr. Kunsági-Máté Sándor
20 Investigations of the conformation changes of proteins by fluorescence and calorimetric methods.
Dr. Kunsági-Máté Sándor
21 Investigations of the conformation changes of proteins by fluorescence and calorimetric methods.
Dr. Kunsági-Máté Sándor
22 Controlling of self-assembly of some hormones by weak interactions.
Dr. Kunsági-Máté Sándor
23 Controlling of self-assembly of some hormones by weak interactions.
Dr. Kunsági-Máté Sándor
24 Controlling of self-assembly of some hormones by weak interactions.
Dr. Kunsági-Máté Sándor
25 Modifications of structure of serum albumins by molecular capsules. Interactions of molecular capsules with aromatic amino
acids at terminated positions.
Dr. Kunsági-Máté Sándor
26 Effect of Molecular Environment on the Formation Kinetics of Complexes of Malvidin-3-O-glucoside with Caffeic Acid and
Catechin
Dr. Kunsági-Máté Sándor
27 Competitive hydrogen bonds associated with the effect of primycin antibiotic on oleic acid as a building block of plasma
membranes.Complex formation between primycin and ergosterol: entropy - driven initiation of modification of the fungal plasma
membrane structure
Dr. Kunsági-Máté Sándor
28 Role of the Conformational Freedom of the Skeleton in the Complex Formation Ability of Resorcinarene Derivatives toward a
Neutral Phenol Guest
Dr. Kunsági-Máté Sándor
Practices
Seminars
Exam topics/questions
Types of molecular interactions.
Chemical equilibrium based on the weak molecular interactions.
Determination of the chemical equilibrium and the stoichiometry of the complexes.
Correlation between the chemical equilibrium and the Gibbs free energy.
Investigation of the weak interaction by spectroscopical methods.
Application of the Jobs method in the fluorescence measurements.
Direct measuring the interaction enthalpy by differential scanning calorimetry.
Interactions of aromatic compounds.
Interactions of bioactive compounds with DNA.
Investigations of model-systems: interactions of calixarenes with phenols and fullerenes.
Packing of drug molecules by molecular containers.
Interactions of bioactive molecules with elements of cell membranes.
Self-assembly of some hormones by weak interactions.
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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112
Participants
Dr. Kunsági-Máté Sándor (UYZM2Q)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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113
OPE-TSS-T MEDICAL APPLICATIONS OF MASS SPECTROMETRY
Course director: DR. LÁSZLÓ MÁRK, associate professor
Department of Biochemistry and Medical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 20 lectures + 0 practices + 0 seminars = total of 20 hours
Course headcount limitations (min.-max.): 3 – 50 Prerequisites: -
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
In medical sciences, emphasis is increasingly placed on instrumental techniques and accurate, quantitative measurements. This course is
give an overall review about the modern mass spectrometry and it shows the medical applications of the MS in the clinical and diagnostic
practice.
Topics:
Introduction to MS. Ionsources, analizators, detectors. Separation techniques. Sample handling. Biomedical sampling. Bioinformatics.
Proteomics, metabolomics and lipidomics. Biomarker discovery. Mass spectrometric imaging techniques.
Conditions for acceptance of the semester
Written exam. Max. absences: 20%.
Mid-term exams
Not possible.
Making up for missed classes
Not possible.
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture slides and notes.
- Notes
- Recommended literature
Vékey et al: Medical Applications of Mass Spectrometry, 2008.
Hoffman et al: Mass Spectrometry, 2007
Lectures
1 Introduction to mass spectrometry
Dr. Márk László
2 Introduction to mass spectrometry
Dr. Márk László
3 Ionsources
Dr. Márk László
4 Analyzers
Dr. Márk László
5 The mass spectrum.
Dr. Márk László
6 Sample matrices, Sampling procedures.
Dr. Márk László
7 Sample pretreatment, separation techniques.
Dr. Márk László
8 Sample pretreatment, separation techniques.
Dr. Márk László
9 Proteomics
Dr. Márk László
10 Proteomics
Dr. Márk László
11 Metabolomics
Dr. Márk László
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114
12 Metabolomics
Dr. Márk László
13 Investigation of endocrine system
Dr. Márk László
14 Investigation of endocrine system
Dr. Márk László
15 Pathological biomarker discovery
Dr. Márk László
16 Pathological biomarker discovery
Dr. Márk László
17 Lipidomics
Dr. Márk László
18 Lipidomics
Dr. Márk László
19 Imaging mass spectrometry
Dr. Márk László
20 Imaging mass spectrometry
Dr. Márk László
Practices
Seminars
Exam topics/questions
Ionsources.
Analizators.
Detectors.
Separation techniques.
Sample handling. Biomedical sampling.
Bioinformatics.
Proteomics.
Metabolomics
Lipidomics.
Biomarker discovery.
Mass spectrometric imaging techniques.
MS of endocrine system.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
115
OPE-BEE-T BASICS OF EPIDEMIOLOGY
Course director: DR. TÍMEA VARJAS, assistant professor
Department of Public Health Medicine [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 20 Prerequisites: -
Topic
During the semester students are acquainted with the basics of epidemiology and epidemiological studies frequently used in scientific
literature. With this knowledge one can easily elucidate and interpret scientific publications.
This course was established especially for pharmacist and dentist students.
Conditions for acceptance of the semester
Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied.
Mid-term exams
Examination: written test
Making up for missed classes
Based on individual consideration
Reading material
- Obligatory literature
- Literature developed by the Department
PPT-presentations (Neptun)
- Notes
- Recommended literature
Lectures
1 The concept of epidemiology
Dr. Szabó István
2 The historical context
Dr. Szabó István
3 Epidemiology and public helath
Dr. Szabó István
4 Achievments in epidemiology
Dr. Szabó István
5 Measuring health and disease
Dr. Szabó István
6 Epidemiological studies
Dr. Szabó István
7 Epidemiological studies
Dr. Szabó István
8 Epidemiological studies
Dr. Szabó István
9 Potential errors in epidemiological studies
Dr. Szabó István
10 The concept of Evidence Based Medicine
Dr. Szabó István
11 Basic epidemiological calculations
Dr. Szabó István
12 Analyzis of selected scientific publications
Dr. Szabó István
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116
Practices
Seminars
Exam topics/questions
Neptun
Participants
Dr. Szabó István (BF4MF6)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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117
OPE-EHS-T HUNGER, SATIETY AND DISTURBANCES OF BODY WEIGHT REGULATION
Course director: DR. LÁSZLÓ CSABA LÉNÁRD, professor emeritus
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OPO-Z2E-T completed + OPO-G2B-T completed
Topic
Based on recent results, feeding related physiological and pathophysiological mechanisms will be discussed. Students will be trained to
understand these mechanisms. The knowledge based on this course will highly contribute to better understanding further clinical studies
on human diseases.
Peripheral and central mechanisms of hunger, satiety, salt appetite and body weight regulation will be discussed. Lectures will include
the following topics: Neural and humoral processes. Peripheral and central glucose-monitoring system. The role of neuropeptides in the
control of feeding and hydromineral balance. Pathological processes: obesity, bulimia, anorexia.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Written exams.
Making up for missed classes
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
Notes taken at the lectures.
- Recommended literature
Lectures
1 Basic parameters: caloric intake, energy expenditure, measurement of food and water intake, body weight and body mass index.
Body weight curves during development, adulthood and senescence.
Dr. Lénárd László Csaba
2 Peripheral and central mechanisms of body weight regulation.
Dr. Lénárd László Csaba
3 Endocrine mechanisms: the role of different hormones.
Dr. Lénárd László Csaba
4 Body weight loss, obesity. Long run pathological consequences of obesity.
Dr. Lénárd László Csaba
5 Hunger and satiety. Motivational mechanisms. Overeating, rejection.
Dr. Lénárd László Csaba
6 Hypothalamic dual centers. The role of limbic system in hunger and satiety.
Dr. Lénárd László Csaba
7 Peripheral glucose related signals. The central glucose monitoring system.
Dr. Lénárd László Csaba
8 Food rewarded learning, the role of reinforcement. Aversive learning, the role of conditioned taste aversion in feeding habits.
Dr. Lénárd László Csaba
9 The sight, odor, taste and texture of foods and their detection in the limbic system. Ingestive and rejective mimetic responses and
their genetic determination. The role of monoamines in the regulation of feeding. Similarities of food rewarded learning and
addictive behavior. The role of dopamine and neuropeptides.
Dr. Lénárd László Csaba
10 Orexigenic and anorexigenic neuropeptides.
Dr. Lénárd László Csaba
11 The role of the central angiotensinergic system in drinking and hydromineral balance.
Dr. Lénárd László Csaba
12 Childhood obesity and cognitive processes. Anorexia nervosa, bulimia and binge eating. Clinical relevance of animal experiments
Dr. Lénárd László Csaba
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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118
Practices
Seminars
Exam topics/questions
Nincsenek előre kreált kérdések, az utolsó előadás utolsó órájában a hallgatók az oktató által feltett kérdésekre kell esszét írnia
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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119
OPE-HL1-T ADVANCED PHYSIOLOGY 1
Course director: DR. TAMÁS OLLMANN, assistant professor
Institute of Physiology [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 98 Prerequisites: -
Topic
Discussion of physiological topics, that not belong to the core subject (based on real examples and case studies). The aim of the subject
is to understand the deep, advanced physiological knowledge and complete the core subject. That develops the problem-solving skills
necessary in the clinical practice and/or during scientific research. Furthermore, it can help to understand another subjects
(pathophysiology, pharmacology) based on physiology as well. The course can be useful for dentistry and pharmacy students as well,
since numerous topics are realted to dentistry or pharmacy as well. The course can contribute to the practical application of evidence
based medicine, as well as to interpret the (sometimes contradictory) scientific literature. Topics of the first semester: cell membrane,
muscle, blood, heart, circulation, respiration, gastrointestinal tract, metabolism, and renal functions.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Writing of case study, online test.
Making up for missed classes
Not necessary, but it is possible in another language.
Reading material
- Obligatory literature
- Literature developed by the Department
The slides will be available on PotePedia.
- Notes
- Recommended literature
Guyton and Hall: Textbook of Medical Physiology
Costanzo: Physiology Cases and Problems (Board Review Series)
Carroll: Problem-Based Physiology
Lectures
1 Evidence based medicine. The journey between observations and facts.
Dr. Ollmann Tamás
2 Homeostasis, fluid compartments, transport mechanisms. The case of the toxic lady.
Dr. Ollmann Tamás
3 Basics of neurophysiology. Membrane potential. Synapses. The importance of ions.
Dr. Ollmann Tamás
4 Autonomic nervous system. Is it better better to be afraid than to be frightened?
Dr. Ollmann Tamás
5 Molecular basics of muscle function. Significance of EMG in the recognition of diseases.
Dr. Ollmann Tamás
6 Metabolism of the muscle. Smooth muscle. The patient with a mysterious muscle weakness.
Dr. Ollmann Tamás
7 Composition of the blood. The significance of blood tests.
Dr. Ollmann Tamás
8 Erythrocytes and hemoglobin. From skin rashes to the bone marrow.
Dr. Ollmann Tamás
9 Leukocytes, immune system. Possible consequences of an insect bite.
Dr. Ollmann Tamás
10 Thrombocytes, coagulation. Tooth extraction and anticoagulants.
Dr. Ollmann Tamás
11 Blood types. The problematic of blood donation.
Dr. Ollmann Tamás
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12 Cardiac rhythm and ECG. The patient with myocardial infarction-like symptoms.
Dr. Ollmann Tamás
13 Cardiac cycle and pumping function. The patient with heart failure.
Dr. Ollmann Tamás
14 Regulation of cardiac functions. Connection of decayed teeth and the heart.
Dr. Ollmann Tamás
15 Blood circulation. The patient with oedema. One sign, many possibilities.
Dr. Ollmann Tamás
16 Pulse and blood pressre. What can we do if we don’t have a sphygmomanometer?
Dr. Ollmann Tamás
17 Regulation of blood circulation. The fainting hunter.
Dr. Ollmann Tamás
18 Respiration, spirometry. Shortness of breath in the bathroom early in the morning.
Dr. Ollmann Tamás
19 The regulation of respiration. Difficulties of the alpinist.
Dr. Ollmann Tamás
20 Gastrointestinal tract. Toilet using habits. The relationship between gut flora and brain. The patient with abdominal pain.
Dr. Ollmann Tamás
21 Regulation of the gastointestinal functions. Digestion and absorption. Consuming too much alcohol.
Dr. Ollmann Tamás
22 Metabolism and thermoregulation. Healthy nutrition and fashionable diets. Facts and misbeliefs.
Dr. Ollmann Tamás
23 Renal functions. The urine and urination. The patient who cannot produce urine.
Dr. Ollmann Tamás
24 Volume and osmoregulation. pH regulation. The disadvantages of panic attacks.
Dr. Ollmann Tamás
Practices
Seminars
Exam topics/questions
The topics of the lectures.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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121
OPF-CME-T COMPUTATIONAL MOLECULAR ENGINEERING
Course director: DR. CSABA HETÉNYI, associate professor
Department of Pharmacology and Pharmacotherapy [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 25 Prerequisites: -
Topic
Computational molecular engineering is a central, modern field of drug design. Theoretical and practical introduction is provided with
details of relevant softwares. In Journal Club sessions, recent research articles will be featured with the students to deepen their knowledge
in the areas discussed during the previous lectures. In this way, the students can discover further connections themselves and make sure
of the usefulness of their newly obtained knowledge in molecular engineering. The lectures will take place weekly or (if possible)
contracted into 4 blocks.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
There is a final test announced at the end of the semester. The test will include multiple choice questions or short essays. A mark is
offered according to the results of the written test or optionally by evaluation of the student's presentation prepared for the Journal Club.
The student can improve the mark according to university regulations.
Making up for missed classes
Replacement is possible according to personal consultation.
Reading material
- Obligatory literature
- Literature developed by the Department
The material of the course including pdfs of lectures and lists of questions will be made downloadable from the web site of the
Department of Pharmacology and Pharmacotherapy or a link will be provided during the lectures / in an e-mail.
- Notes
- Recommended literature
Lectures
1 Visualization of macromolecules. Programs VMD and PyMol
Dr. Hetényi Csaba
2 Structural measurements, editing and comparisons
Dr. Hetényi Csaba
3 An introduction to macromolecular structures. Main features of peptide and protein structures. Experimental sources of structural
data of biopolymers
Dr. Hetényi Csaba
4 Examples on structural variability. The role of conformational disorders of proteins in the pathomechanism of Alzheimer’s and
prion diseases. Myosin, the motor protein: same sequence with different structures
Dr. Hetényi Csaba
5 Surface and volume calculations
Dr. Hetényi Csaba
6 Simple methods for binding site detection and cavity search. Program PASS
Dr. Hetényi Csaba
7 Hierarchy of calculation methods. Fundamentals of QM
Dr. Hetényi Csaba
8 Programs for molecular modeling
Dr. Hetényi Csaba
9 Principles of molecular mechanics (MM). Force fields. Bonding and non-bonding interactions
Dr. Hetényi Csaba
10 The general algorithm of MM programs. Program packages. TINKER
Dr. Hetényi Csaba
11 Journal club 1. Computational methods and strategies of drug design
Dr. Hetényi Csaba
12 Journal club 2. Complementary approaches
Dr. Hetényi Csaba
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Practices
Seminars
Exam topics/questions
Lists of questions will be provided at the end of each lecture specifying the required knowledge.
Participants
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123
OPF-CY2-T CYBERNETICS FOR MEDICAL, DENTISTRY AND PHARMACY STUDENTS 2
Course director: LÁSZLÓ ZOLTÁN PÉCZELY, assistant professor
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 30 Prerequisites: -
Topic
Cybernetics embracing more disciplines deals with the control, regulation, information flow and processing occuring in expediently
working dinamical systems. The most important goal of our subject is to help the students understand the functional principles of the
regulatory systems, mainly those of the human body. Furthermore, we would like to familiarize the students with how the balance of the
regulatory systems can be maintained by their wide adaptive and learning capacity/capability. We would like to demonstrate that etiology
of many diseases can be explained by the disruption of balance, how the balance can be restored by the therapy and, at the same time,
how the therapy can cause the shift of the balance in other parts of the system (side effect). In addition to the biological systems, both
the functional description of the artificial regulatory systems and the artificial intelligence will be addressed. In the second semester the
following topics are discussed: neuroendocrin regulation (II), nervous system and immune system as networks, integrative regulation of
motion, movement disorders, learning in artificial and biological systems, models of psychiatric diseases, regulatory disturbances.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Writing of case study, online test.
Making up for missed classes
Not necessary, but it is possible in another language
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Guyton & Hall: Textbook of Medical Physiology
V. V. Purin, R. M. Buyevskiy: Introduction To Medical Cybernetics
Peter Norvig, Stuart J. Russell: MI modern megközelítésben
James Kneer, James Sneyd: Mathematical Physiology I.: Cellular Physiology
James Kneer, James Sneyd: Mathematical Physiology II.: System Physiology
Lectures
1 Networks: communication among cells, organs, organ systems; principles. Nested hierarchical systems.
Dr. Péczely László Zoltán
2 Networks: nervous system (neuroendocrine system) and immune system, interactions, regulatory disturbances.
Dr. Péczely László Zoltán
3 Detection in living organisms and artificial systems.
Dr. Péczely László Zoltán
4 System-level description of the integrative regulation of motion, models, regulatory disturbances and their restitution.
Dr. Péczely László Zoltán
5 Behaviour and motivation: high-level organization to maintain the integrity of the organism.
Dr. Péczely László Zoltán
6 Mathematical models of adaptation, learning I : supervised and non-supervised learning in artificial systems.
Dr. Péczely László Zoltán
7 Mathematical models of adaptation, learning II : supervised and non-supervised learning in biological systems.
Dr. Péczely László Zoltán
8 Mathematical models of adaptation, learning III: reinforcement learning in artificial systems.
Dr. Péczely László Zoltán
9 Mathematical models of adaptation, learning IV: reinforcement learning in biological systems.
Dr. Péczely László Zoltán
10 Modeling of psychiatric diseases, regulatory disturbances, options for interventions I
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124
Dr. Péczely László Zoltán
11 Modeling of psychiatric diseases, regulatory disturbances, options for interventions II
Dr. Péczely László Zoltán
12 Adaptation on the level of evolution: learning of species.
Dr. Péczely László Zoltán
Practices
Seminars
Exam topics/questions
The topics of the lectures
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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125
OPF-CSU-T MIRACLES OF LIVING MATERIALS ("REALISTIC" BIOCHEMISTRY)
Course director: DR. BALÁZS VERES, associate professor
Department of Biochemistry and Medical Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 45 Prerequisites: -
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
The aim of the course is to enlighten and uncover the biochemical background of those topics which are selected as recent „mainstream”
natural science issues. The topic spectrum is wide enough to cover problems from synthetic biology through dopes in sport until toxins
and poisons of plants, fungi and animals. There is a special session about the physical, chemical and medical Nobel prizes from the last
decade to get insight to the hottest fields of natural sciences.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Hand-made info-graph about a selected topic.
Making up for missed classes
There is no possibility to make up.
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture slides (in pdf format) will be available for the students. WEB links and additional on line materials will be included as well.
- Notes
Lecture slides (in pdf format) will be available for the students. WEB links and additional on line materials will be included as well.
- Recommended literature
Lecture slides (in pdf format) will be available for the students. WEB links and additional on line materials will be included as well.
Lectures
1 Human genome project, gene therapy, epigenetics
Dr. Veres Balázs
2 DNA sequencing, PCR, CSI
Dr. Veres Balázs
3 Playing God: synthetic biology
Dr. Veres Balázs
4 Personalized genome-based medicine: access to a healthier world.
Dr. Veres Balázs
5 Superman: doping in sport and brain doping
Dr. Veres Balázs
6 Eugenics: the scientific horror of the XX. century.
Dr. Veres Balázs
7 Artificial life. The future of life forms - including humans - on Earth.
Dr. Veres Balázs
8 Cancer, AIDS: beyond therapy
Dr. Veres Balázs
9 Biochemistry of neurodegenerative disorders
Dr. Veres Balázs
10 Antibiotics: past, present, future
Dr. Veres Balázs
11 Home delivery: nanoparticles, liposomes
Dr. Veres Balázs
12 Nature strikes back: toxins of plants, fungi and animals
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126
Dr. Veres Balázs
Practices
Seminars
Exam topics/questions
Exam topics are the topics of the lectures during the course.
Participants
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127
OPF-DR2-T DRUG DESIGN 2
Course director: DR. CSABA HETÉNYI, associate professor
Department of Pharmacology and Pharmacotherapy [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 25 Prerequisites: -
Topic
The course is a continuation of its parent course Drug Design. Additional details of selected topics of the parent course and also new
topics are provided. In Journal Club sessions, recent research articles will be featured with the students to deepen their knowledge in the
areas discussed during the previous lectures. In this way, the students can discover further connections themselves and make sure of the
usefulness of their newly obtained knowledge in drug design. The lectures will take place weekly or (if possible) contracted into 4 blocks.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
There is a final test announced at the end of the semester. The test will include multiple choice questions or short essays. A mark is
offered according to the results of the written test or optionally by evaluation of the student's presentation prepared for the Journal Club.
The student can improve the mark according to university regulations.
Making up for missed classes
Replacement is possible according to personal consultation.
Reading material
- Obligatory literature
- Literature developed by the Department
The material of the course including pdfs of lectures and lists of questions will be made downloadable from the web site of the
Department of Pharmacology and Pharmacotherapy or a link will be provided during the lectures / in an e-mail.
- Notes
- Recommended literature
Patrick GL: An Introduction to Medicinal Chemistry, Oxford University Press
Lectures
1 Rational design: main concepts, phases, and techniques
Dr. Hetényi Csaba
2 Target-based optimization. Case study: ACE inhibitors
Dr. Hetényi Csaba
3 Ligand libraries, combinatorial synthesis, screening, modifications, and the pharmacophore. Case study: Artemisinin
Dr. Hetényi Csaba
4 Antiviral design
Dr. Hetényi Csaba
5 Antibacterial design
Dr. Zsidó Balázs Zoltán
6 Targeting ion channels
Dr. Zsidó Balázs Zoltán
7 Targeting receptors 1.
Dr. Zsidó Balázs Zoltán
8 Targeting receptors 2.
Dr. Zsidó Balázs Zoltán
9 Targeting the signaling pathways
Dr. Zsidó Balázs Zoltán
10 Journal club 1. Mechanisms and ligand optimizations
Dr. Hetényi Csaba
11 Journal club 2. Anti-cancer agents and ion channels
Dr. Hetényi Csaba
12 Test
Dr. Hetényi Csaba
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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128
Practices
Seminars
Exam topics/questions
Lists of questions will be provided at the end of each lecture specifying the required knowledge.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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129
OPF-ESP-T EXERCISE AND SPORT PHYSIOLOGY
Course director: DR. PÉTER KÓBOR, assistant professor
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OPO-H1E-T completed
Topic
These days, it is apparent in almost every age group that the number of people dedicated to healthy lifestyle (including physical exercise)
is increasing. Simultaneously, the list of sport activities available in the university is expanding as well, consequently there are more and
more students doing sports on an amateur or higher level. Primary aim of this course is to unfold the exercise- and sports-related aspects
of physiology that have not been discussed during the regular physiology class, however these facts might be not only fascinating for
students involved in sport activities or treatment of athletes later on but they have very important theoretical and practical significance
as well.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Multiple choice test on the last lecture.
Making up for missed classes
It is not necessary but possible in other language (Hungarian).
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture slides will be provided for the students.
- Notes
- Recommended literature
Terry J. Housh, Dona J. Housh & Herbert A. deVries - Applied exercise and sport physiology with labs
William D. McArdle, Frank L. Katch & Victor L. Katch - Exercise physiology (Nutrition, energy, and human performance)
Lectures
1 Active and passive organs of moving
Dr. Kóbor Péter
2 The blood and the cardiovascular system
Dr. Kóbor Péter
3 Respiration
Dr. Kóbor Péter
4 Metabolism
Dr. Kóbor Péter
5 Water homeostasis, kidney function
Dr. Kóbor Péter
6 The nervous system
Dr. Kóbor Péter
7 The endocrine system
Dr. Kóbor Péter
8 The immune system
Dr. Kóbor Péter
9 Applied sport physiology 1 (division of physical exercises, physiological aspects of training, doping)
Dr. Kóbor Péter
10 Applied sport physiology 2 (improving endurance, speed, flexibility)
Dr. Kóbor Péter
11 Health benefits of physical activity
Dr. Kóbor Péter
12 Test writing
Dr. Kóbor Péter
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130
Practices
Seminars
Exam topics/questions
The topics are matching with those of the lectures.
Participants
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131
OPF-GMI-T DAILY ROUTINE AND CHALLENGES IN VARIOUS FIELDS OF THE PHARMACY PROFESSION
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 3 – 30 Prerequisites: -
Topic
This course intends to provide insight into various career opportunities for graduates with a degree in pharmacy. Invited speakers working
in various fields of the pharmaceutical profession talk about characteristic features of their job, including daily routine, challenging
situations and peculiarities they have come accross. Speakers represent pharmacists working in community pharmacies, clinical
pharmacies, in the pharmaceutical industry, as well as at health authorities and at universities or research institutes.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Active participation is expected from students. They should be prepared to ask questions from each speaker and they are requested to
take notes on each occasion. These notes should be handed in to the course instructor at the end of each class.
The final grade is based on student activity in class and the written notes they have taken on each occassion.
Making up for missed classes
There is no opportunity to make up for absences, since different speakers are invited to each class.
Reading material
- Obligatory literature
None
- Literature developed by the Department
- Notes
- Recommended literature
Lectures
1 Invited speaker. Pharmacist at a community pharmacy.
Dr. Farkas Ágnes
2 Invited speaker. Pharmacist at a community pharmacy.
Dr. Farkas Ágnes
3 Invited speaker. Pharmacist at a clinical pharmacy.
Dr. Lankó Erzsébet
4 Invited speaker. Pharmacist at a clinical pharmacy.
Dr. Lankó Erzsébet
5 Invited speaker. Pharmacist working in the pharmaceutical industry.
Dr. Farkas Ágnes
6 Invited speaker. Pharmacist working in the pharmaceutical industry.
Dr. Farkas Ágnes
7 Invited speaker. Pharmacist working at a university.
Dr. Poór Miklós
8 Invited speaker. Pharmacist working at a university.
Dr. Poór Miklós
9 Invited speaker. Pharmacist working in a research institute.
Dr. Farkas Ágnes
10 Invited speaker. Pharmacist working in a research institute.
Dr. Farkas Ágnes
11 Invited speaker. Pharmacist working at the health authorities.
Dr. Kuzma Mónika
12 Invited speaker. Pharmacist working at the health authorities.
Dr. Kuzma Mónika
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132
13 Invited speaker. Daily routine of a specialty pharmacist.
Dr. Szabóné Dr. Schirm Szilvia
14 Invited speaker. Daily routine of a specialty pharmacist.
Dr. Szabóné Dr. Schirm Szilvia
Practices
Seminars
Exam topics/questions
No exam questions.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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133
OPF-H4A-T MEDICAL HUNGARIAN 4A - BASICS OF MEDICAL COMMUNICATION FOR STUDENTS OF
PHARMACY
Course director: GABRIELLA NAGY, assistant lecturer
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OPF-H3A-T completed + OPF-H4B-T parallel
Topic
This course provides language and communicative functions in the areas of medications, the application of medications and prescribing
medications and is also meant to give opportunities for putting skills and knowledge into practice in preparation for the final exam.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
--
Making up for missed classes
In the case of absences up to 25% of total class time, oral examination will have to be taken.
Reading material
- Obligatory literature
- Literature developed by the Department
Hand-outs
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Types and forms of medications - Review
2 Application of medications - Review
3 Instructions concerning the use of medications: pain relievers
4 Instructions concerning the use of medications: pain relievers
5 Instructions concerning the use of medications: antipyretics
6 Instructions concerning the use of medications: cough medications
7 Instructions concerning the use of medications: antidiabetics
8 Instructions concerning the use of medications: spasmolytics
9 Instructions concerning the use of medications: sleeping pills
10 Instructions concerning the use of medications: steroids
11 Instructions concerning the use of medications: antibiotics
12 Instructions concerning the use of medications: antiinflammatory medications
13 Instructions concerning the use of medications: emetics and antiemetics
14 Instructions concerning the use of medications: eye, ear and nasal drops
15 Instructions concerning the use of medications: medications applied to the skin
16 Test 1
17 Instructions concerning the use of medications: suppository
18 First aid instruments
19 Preparation for the Final Exam in Medical Hungarian
20 Preparation for the Final Exam in Medical Hungarian
21 Preparation for the Final Exam in Medical Hungarian
22 Preparation for the Final Exam in Medical Hungarian
23 Preparation for the Final Exam in Medical Hungarian
24 Test 2. Course evaluation
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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134
Exam topics/questions
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Ronczykné Berta Anikó (CJZOFU), Szalai-Szolcsányi Judit
(RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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135
OPF-H4B-T MEDICAL HUNGARIAN 4B - MEDICAL COMMUNICATION IN PRACTICE FOR STUDENTS OF
PHARMACY
Course director: GABRIELLA NAGY, assistant lecturer
Department of Languages for Specific Purposes [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OPF-H3B-T completed + OPF-H4A-T parallel
Topic
This course provides language and communicative functions in the areas of medications, the application of medications and prescribing
medications and is also meant to give opportunities for putting skills and knowledge into practice in preparation for the final exam.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Making up for missed classes
In the case of absences up to 25% of total class time, oral examination will have to be taken.
Reading material
- Obligatory literature
- Literature developed by the Department
Hand-outs
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Types and forms of medications - Review
2 Application of medications - Review
3 Instructions concerning the use of medications: pain relievers - Pharmacist-patient dialogues
4 Instructions concerning the use of medications: pain relievers- Pharmacist-patient dialogues
5 Instructions concerning the use of medications: antipyretics- Pharmacist-patient dialogues
6 Instructions concerning the use of medications: cough medications- Pharmacist-patient dialogues
7 Instructions concerning the use of medications: antidiabetics- Pharmacist-patient dialogues
8 Instructions concerning the use of medications: spasmolytics- Pharmacist-patient dialogues
9 Instructions concerning the use of medications: sleeping pills- Pharmacist-patient dialogues
10 Instructions concerning the use of medications: steroids- Pharmacist-patient dialogues
11 Instructions concerning the use of medications: antibiotics- Pharmacist-patient dialogues
12 Instructions concerning the use of medications: antiinflammatory medications- Pharmacist-patient dialogues
13 Instructions concerning the use of medications: emetics and antiemetics- Pharmacist-patient dialogues
14 Instructions concerning the use of medications: eye, ear and nasal drops- Pharmacist-patient dialogues
15 Instructions concerning the use of medications: medications applied to the skin- Pharmacist-patient dialogues
16 Test 1
17 Instructions concerning the use of medications: suppository- Pharmacist-patient dialogues
18 First aid instruments
19 Preparation for the Final Exam in Medical Hungarian
20 Preparation for the Final Exam in Medical Hungarian
21 Preparation for the Final Exam in Medical Hungarian
22 Preparation for the Final Exam in Medical Hungarian
23 Preparation for the Final Exam in Medical Hungarian
24 Test 2. Course evaluation
Exam topics/questions
http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag
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136
Participants
Dávidovics Anna (U5A10Z), Dr. Hegedűs Anita (TQQEMK), Dr. Hild Gabriella (HILSWV), Dr. Németh Tímea (X8VRGN), Dr. Rébék-
Nagy Gábor (DGOZG1), Dr. Warta Vilmos (SJYRAV), Eklicsné Dr. Lepenye Katalin (JMXXSC), Krommer Zoltán (MQ5HNA),
Kurdiné Molnár Eszter (VUCECC), Nagy Gabriella (CYMRX3), Ronczykné Berta Anikó (CJZOFU), Szalai-Szolcsányi Judit
(RBGAPH), Szántóné Dr. Csongor Alexandra (UDKY0J)
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137
OPF-HB2-T HOW TO ACHIEVE BETTER GRADE IN ORGANIC CHEMISTRY 2
Course director: DR. BALÁZS BOGNÁR, assistant professor
Department of Organic and Pharmacological Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 0 practices + 10 seminars = total of 10 hours
Course headcount limitations (min.-max.): 2 – 20 Prerequisites: OPA-S1E-T completed + OPA-S2E-T parallel
Topic
The aim of the course is to help the students to understand the important reaction mechanisms, and find the connections between the
different topics.
1. Revision of addition and substitution reactions
2. Basicity and reactivity of amines
3-4. Reactions of carbonyl compounds, nucleophilic additions, condensations
5. Isomerisations in carbohydrates
6. 1. test
7. Acidity of carboxylic acids
8. Reactions of carboxylic acids and their derivatives
9. Aromatic substitutions of heteroaromatics
10. 2. test
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Nincs.
Making up for missed classes
Nincs.
Reading material
- Obligatory literature
- Literature developed by the Department
The worksheets will be granted on the seminar.
- Notes
- Recommended literature
Estelle K. Meislich; Herbert Meislich; Jacob Sharefkin: Schaum’s Series 3000 Solved Problems In Organic Chemistry, McGraw-
Hill, Inc., New York, 1994.
T. W. Graham Solomons: Organic Chemistry, 7th edition, Wiley and Sons, New York, 2000.
John McMurry, Eric Simanek: Fundamentals of Organic Chemistry, 6th edition, Thomson Brooks/Cole, Belmont, 2007.
Lectures
Practices
Seminars
1 Revision of the most important reaction mechanisms from the 1. semester: addition and substitution reactions.
Dr. Bognár Balázs
2 Basicity, synthesis and reactions of amines.
Dr. Bognár Balázs
3 Reactions of carbonyl compounds, nucleophilic additions, condensations with S,- N,- O-nucleophiles.
Dr. Bognár Balázs
4 Reactions of carbonyl compounds, nucleophilic additions, condensations with C-nucleophiles.
Dr. Bognár Balázs
5 Isomerisations and reactions in carbohydrates.
Dr. Bognár Balázs
6 1. test: amines, aldehydes, ketons, carbohydrates.
Dr. Bognár Balázs
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7 Acidity and reactions of carboxylic acids.
Dr. Bognár Balázs
8 Reactions of carboxylic acids and their derivatives (amides, esters anhydrides).
Dr. Bognár Balázs
9 Aromatic nucleophilic and electrophilic substitutions of heteroaromatics.
Dr. Bognár Balázs
10 2. test: carboxylic acids and its derivatives, heterocycles.
Dr. Bognár Balázs
Exam topics/questions
There is no exam.
Participants
Dr. Bognár Balázs (U34DM4)
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139
OPF-HFG-T GREAT DISCOVERIES IN PHARMACOLOGY
Course director: DR. KRISZTINA HARNTNER-POHÓCZKY, assistant professor
Department of Pharmacology [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 1 – 100 Prerequisites: -
Topic
The aim of the lectures is to show how and through what discoveries pharmaceutical science came to today's modern age. Thanks to the
famous scientists presented their achieved breakthroughs in their own age have fundamentally changed scientific thinking. Pharmacology
has a rich and long-standing heritage, which today completed with new disciplines such as molecular biology and genetics, which provide
powerful tools for study pharmacodynamics and pharmacokinetics. During the semester, students will gain insight into the
pharmacological methods in those ages when researchers achieved their world-famous discoveries without today’s sophisticated tools.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
During the semester, each student have to give a short presentation on a chosen topic related to drug discovery.
Making up for missed classes
There is no possibility to make up the lectures.
Reading material
- Obligatory literature
- Literature developed by the Department
Own educational material will be available in digital form in the Neptun Meet Street.
- Notes
- Recommended literature
Ronald P. Rubin: A brief history of great discoveries in pharmacology: in celebration of the centennial anniversary of the founding
of the american society of pharmacology and experimental therapeutics, 2007: Pharmacological Reviews 59: 289-359.
Lectures
1 Important principles of drug treatments: Sir James Black, Gertrude Elion és és Geroge Hitchins.
Hartnerné Dr. Pohóczky Krisztina
2 Discoveries of János Kabay.
Hartnerné Dr. Pohóczky Krisztina
3 The discovery of penicillin and its curative effects in various infectious diseases: Sir Alexander Fleming, Cecil Paine, Harold
Raistrick, Ernst Chain, and Sir Howard Florey.
Hartnerné Dr. Pohóczky Krisztina
4 The scientific impact of Antal Bayer.
Hartnerné Dr. Pohóczky Krisztina
5 The roles of prostaglandins and related biologically active substances: Sune Bergstrom, Bengt Samuelsson, and John Vane.
Hartnerné Dr. Pohóczky Krisztina
6 Richter Gedeon and the kalmopyrin.
Hartnerné Dr. Pohóczky Krisztina
7 Discovery of cyclic AMP and protein phosphorylation as a key mechanism in the regulation of cellular function: Earl W.
Sutherland, Edwin G. Krebs and Edmond H. Fischer.
Hartnerné Dr. Pohóczky Krisztina
8 Career and research of Albert Szent-Györgyi.
Hartnerné Dr. Pohóczky Krisztina
9 G proteins and their role in signal transduction: Rodbell and Alfred G. Gilman.
Hartnerné Dr. Pohóczky Krisztina
10 Life and researh of Louis Pasteur.
Hartnerné Dr. Pohóczky Krisztina
11 The history of chemotherapy: from the chemical weapons to Sydney Farber.
Dr. Szőke Éva
12 History of capsaicin research, discovery of capsaicin-sensitive sensory nerve endings and their role: Miklós Jancsó and János
Szolcsányi.
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140
Dr. Szőke Éva
13 Nitric oxide as a signaling molecule of the cardiovascular system: Robert Furchgott, Ferid Murad és Louis Ignarro.
Hartnerné Dr. Pohóczky Krisztina
14 József Béres; inventor and scientist.
Hartnerné Dr. Pohóczky Krisztina
Practices
Seminars
Exam topics/questions
The final mark will based on the short oral presentation of a famous discovery or famous researcher.
Participants
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141
OPF-QBI-T QUANTUM BIOLOGY: QUANTUM PHENOMENA IN BIOLOGICAL PROCESSES
Course director: DR. KRISZTIÁN KVELL, associate professor
Department of Pharmaceutical Biotechnology [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 50 Prerequisites: OPO-G2B-T completed
Topic
Course description:
Based on common scientific approach quantum phenomena are not relevant in biological processes. The living cell has relatively large
dimensions, is filled with hydrated vibrating macromolecules, and follows the rules thermodynamics rather than quantum mechanics.
Yet, besides attractive theories, experimental data also accumulate suggesting that living cells readily exploit quantum phenomena.
Several biological processes require quantum biology approach for full understanding. These include photosynthesis, various enzyme
activities, DNA mutation accumulation, avian magnetoreception, mammalian olfaction etc. During the course students get familiar with
the quantum biology explanation of these biological processes.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
There will be several occasions for the students to rewrite midterm tests.
Making up for missed classes
Students will get e-learning material to cope to follow the course at home.
Reading material
- Obligatory literature
Life on the edge: The coming of age of quantum biology, Johnjoe McFadden, Jim Al-Khalili, Broadway Books (2016) 368 pages,
ISBN-13: 978-0307986825
- Literature developed by the Department
Topics:
- Quantum phenomena and basics terms
- Thermodynamics vs quantum mechanics
- Structural characteristics of biological macromolecules
- Quantum biology approach of the living cell
- Quantum biology approach of cell death
- Quantum biology approach of molecular energy transport
- Quantum biology approach of genetic mutation accumulation
- Quantum biology approach of photosynthesis
- Quantum biology approach of enzyme activity
- Quantum biology approach of avian magnetoreception
- Quantum biology approach of mammalian olfaction
- Quantum biology approach of the conscious mind
- Basic principles of quantum computers and quantum biology analogies
- Written exam
- Notes
Life on the edge: The coming of age of quantum biology, Johnjoe McFadden, Jim Al-Khalili, Broadway Books (2016) 368 pages,
ISBN-13: 978-0307986825
- Recommended literature
Life on the edge: The coming of age of quantum biology, Johnjoe McFadden, Jim Al-Khalili, Broadway Books (2016) 368 pages,
ISBN-13: 978-0307986825
Lectures
1 Quantum phenomena and basics terms I.
Dr. Lukács András Szilárd
2 Quantum phenomena and basics terms II.
Dr. Lukács András Szilárd
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142
3 Thermodynamics vs quantum mechanics I.
Dr. Lukács András Szilárd
4 Thermodynamics vs quantum mechanics II.
Dr. Lukács András Szilárd
5 Structural characteristics of biological macromolecules I.
Dr. Kvell Krisztián
6 Structural characteristics of biological macromolecules II.
Dr. Kvell Krisztián
7 Quantum biology approach of the living cell I.
Dr. Buzás Péter
8 Quantum biology approach of the living cell II.
Dr. Buzás Péter
9 Quantum biology approach of cell death I.
Dr. Buzás Péter
10 Quantum biology approach of cell death II.
Dr. Buzás Péter
11 Quantum biology approach of molecular energy transport I.
Dr. Pál Szilárd
12 Quantum biology approach of molecular energy transport II.
Dr. Pál Szilárd
13 Quantum biology approach of genetic mutation accumulation I.
Dr. Kvell Krisztián
14 Quantum biology approach of genetic mutation accumulation II.
Dr. Kvell Krisztián
15 Written exam
Dr. Kvell Krisztián
16 Quantum biology approach of photosynthesis I.
Dr. Hoffmann Gyula
17 Quantum biology approach of photosynthesis II.
Dr. Hoffmann Gyula
18 Quantum biology approach of enzyme activity I.
Dr. Pál Szilárd
19 Quantum biology approach of enzyme activity II.
Dr. Pál Szilárd
20 Quantum biology approach of avian magnetoreception I.
Dr. Hoffmann Gyula
21 Quantum biology approach of avian magnetoreception II.
Dr. Hoffmann Gyula
22 Quantum biology approach of mammalian olfaction I.
Dr. Hoffmann Gyula
23 Quantum biology approach of mammalian olfaction II.
Dr. Hoffmann Gyula
24 Quantum biology approach of the conscious mind I.
Dr. Sik Attila Gábor
25 Quantum biology approach of the conscious mind II.
Dr. Sik Attila Gábor
26 Basic principles of quantum computers and quantum biology analogies I.
Dr. Kvell Krisztián
27 Basic principles of quantum computers and quantum biology analogies II.
Dr. Kvell Krisztián
28 Written exam
Dr. Kvell Krisztián
Practices
Seminars
Exam topics/questions
https://www.dropbox.com/home/munka/Kvantumbiológia?preview=LifeOnTheEdge2014.pdf
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143
Participants
Dr. Ábrahám István Miklós (HQI9FH), Dr. Hoffmann Gyula (JB4TQB), Dr. Kvell Krisztián (Y0GLOV), Dr. Lukács András Szilárd
(LZ2I4Q), Dr. Miskei György Zsolt (PTAG3C), Dr. Pál Szilárd (FYF5E9), Dr. Sik Attila Gábor (A12OXW)
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144
OPF-SKI-T BASICS OF CHEMICAL INFORMATICS
Course director: DR. GYŐZŐ KORNÉL KULCSÁR, assistant professor
Department of Pharmaceutical Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 5 – 24 Prerequisites: OPA-S1E-T completed
Topic
The aim of the course is to give the students a basic knowledge of chemical informatics. An overview of how computers have become
the indispensable tools for chemical experiments, measurements, regulatory and performance evaluation tasks, and theoretical chemistry
tests.
We cover the chemical sciences from used software, web resources, which we believe are most useful during academic years in chemical
science student work and in preparing theses. Students can learn the basics of molecular modeling, the use of databases available in the
University (ScienceDirect, PubMed, SciFinder ...), the general steps of the search.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the lectures is obligatory.
Maximum three absences can be accepted.
Making up for missed classes
There is no opportunity to make up missed classes.
Reading material
- Obligatory literature
- Literature developed by the Department
The worksheets will be handed on the seminars.
- Notes
- Recommended literature
https://docs.chemaxon.com/display/docs/MarvinSketch+User%27s+Guide
http://www.cambridgesoft.com/support/DesktopSupport/Documentation/Manuals/files/chemdraw_9_english.pdf
Lectures
1 Introduction, simple database managers (literature, citations, etc.) in chemistry.
Dr. Kulcsár Győző Kornél
2 Introduction into the Molecular Modeling Software”s
Dr. Kulcsár Győző Kornél
3 Molecular modeling - structural fundamentals
Dr. Kulcsár Győző Kornél
4 Molecular modeling - structure optimization
Dr. Kulcsár Győző Kornél
5 Molecular modeling - molecules and interaction with the surroundings
Dr. Kulcsár Győző Kornél
6 Molecular modeling - molecular Interactions
Dr. Kulcsár Győző Kornél
7 Molecular modeling - applied modeling in drug research
Dr. Kulcsár Győző Kornél
8 Chemical databases I.
Dr. Kulcsár Győző Kornél
9 Chemical databases II.
Dr. Kulcsár Győző Kornél
10 Using a text editor application in chemistry
Dr. Kulcsár Győző Kornél
11 Handling bibliography
Dr. Kulcsár Győző Kornél
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12 Apply a spreadsheet program in chemistry
Dr. Kulcsár Győző Kornél
13 Apply a vector drawing program. Creating a flowchart of science, chemical content and flow charts. Photos and videos in
chemistry, the basics of image processing.
Dr. Kulcsár Győző Kornél
14 Presentation of student results, evaluation of the semester
Dr. Kulcsár Győző Kornél
Practices
Seminars
Exam topics/questions
Written test covering the topics of the lectures.
Participants
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146
OPF-TG2-T STUDENT PROJECT RESEARCH FOR STUDENTS OF PHARMACEUTIST PROGRAMME 2
Course director: DR. GYÖRGYI HORVÁTH, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OPF-TG1-T completed
Topic
The course aims at promoting of students to make student research projects on the field of pharmaceutical sciences. Furthermore, we
wish to give individual possibilities of students to perform experiments in the different pharmaceutical institutes involved into Students
Research Society.
Conditions for acceptance of the semester
The continuous student’s work is recommended. The continuous enrollment of consecutive courses can be stopped and continued in
further semesters.
The prerequisite of this course (TDK 2): registration of the student in the database of Students’ Research Society and the fulfillment of
the Student Project Research for Students of Pharmaceutist Programme 1 course.
Mid-term exams
TG2
- Introduction of conference abstract or conference manuscript (student is co-author) for the course supervisor at the end of 13th week of
the semester.
- Written report on the work performed by the student. It must be sent to the course supervisor at the end of 13th week of the semester.
- Among the two conditions, one of them should be made at least.
Making up for missed classes
There is no possibility.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
ScienceDirect database
Lectures
Practices
Seminars
Exam topics/questions
Not applicable.
Participants
Dr. Horváth Györgyi (GDLTCH), Dr. Poór Miklós (ARWF5Z), Dr. Vida Róbert György (BN08GS)
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147
OPF-VAN-T IRON METABOLISM: FROM MOLECULAR MECHANISMS TO CLINICAL CONSEQUENCES
Course director: DR. EDINA PANDUR, assistant professor
Department of Pharmaceutical Biology [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 4 – 30 Prerequisites: OPO-G2B-T completed
Topic
During the course we will discuss the role of iron in the metabolism. We will deal with the iron demand of microorganisms and with the
role of iron in the protective mechanisms against bacterial infections. We will discuss the possibilities of iron uptake and intracellular
iron utilistaion, especially heme synthesis, and the syntesis of iron-sulfur clusters. The iron storage and iron mobilization from stores will
be discussed in details. We reveal the functions of iron regulatory factors, their crosstalks, and the functions of the iron-containing
proteins. Based on the brand new literature we discuss the the positive and negative regulators of the master iron regulator hepcidin.
During the course we will deal with the different types of iron disorders and diseases (anemias, thalassemias, secondary iron overload,
hemochromatosis) their genetic background, and therapeutic approaches. Based on the most actual findings the role of iron in the
developpment of neurodegenerative diseases (Parkinson’s disease, Alzheimer’s disease and Huntington’s disease) will be also discussed.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
One midterm exam, one possibility for retake.
Making up for missed classes
Personal consultation
Reading material
- Obligatory literature
- Literature developed by the Department
The lectures will be uploaded to the Neptun Meet street.
- Notes
- Recommended literature
Robert Crichton: Iron metabolism 4th Edition
Sarika Arora: Iron metabolism
Lectures
1 Solution chemistry of iron
Jánosa Gergely
2 Interactions between iron other metal ions
Jánosa Gergely
3 The Importance of Iron for Biological Systems: haemoproteins, iron-sulfur proteins, other iron containing proteins
Dr. Pandur Edina
4 Microbial Iron Transport and Metabolism
Jánosa Gergely
5 Iron Acquisition by pathogens
Jánosa Gergely
6 Iron metabolism of yeasts
Pap Ramóna
7 Iron uptake by plants
Dr. Pandur Edina
8 Iron homeostasis in plants
Dr. Pandur Edina
9 Cellular Iron Uptake and Export in Mammals: iron transporters
Dr. Pandur Edina
10 Mammalian intestinal iron absorption
Dr. Pandur Edina
11 Intracellular Iron Storage
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148
Dr. Pandur Edina
12 Intracellular Iron Metabolism and Cellular Iron Homeostasis I: Labile iron pool, mitochondrial iron uptake and metabolism
haem biosynthesis
Pap Ramóna
13 Intracellular Iron Metabolism and Cellular Iron Homeostasis II: synthesis of iron-sulfur clusters, functions of iron responsive
elements and iron regulatory proteins
Pap Ramóna
14 Regulation of Systemic Iron Metabolism: positive regulators of hepcidin
Dr. Pandur Edina
15 Regulation of Systemic Iron Metabolism: negative regulators of hepcidin
Dr. Pandur Edina
16 Pathophysiology of Iron metabolism: anemias (IDA, IRIDA, ACD)
Pap Ramóna
17 Pathophysiology of Iron metabolism: thalassemias and secondary iron overload
Jánosa Gergely
18 Pathophysiology of Iron metabolism: hemochromatosis
Dr. Pandur Edina
19 Pathophysiology of Iron metabolism: therapeutic approaches
Pap Ramóna
20 Iron disorders and Laboratory parameters 1.
Dr. Pandur Edina
21 Iron disorders and Laboratory parameters 2.
Dr. Pandur Edina
22 Iron and oxidative stress
Dr. Pandur Edina
23 Iron and immunity 1.
Pap Ramóna
24 Iron and immunity 2.
Pap Ramóna
25 Brain iron metabolism
Dr. Pandur Edina
26 The role of iron in neurodegenerative diseases
Dr. Pandur Edina
27 Iron and cancer 1.
Dr. Pandur Edina
28 Iron and cancer 2.
Dr. Pandur Edina
Practices
Seminars
Exam topics/questions
The questions will be formed from the learning material of the lectures.
Participants
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149
OPE-BKM-T BASIC METHODS OF SCIENTIFIC RESEARCH
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 15 Prerequisites: OPA-B2E-T completed + OPA-B2G-T completed
Topic
The course aims at introducing students to the basic steps of scientific research, guiding them through stages of becoming an independent
researcher. The course covers each step of the research process, from preparing a research plan to evaluating and reporting data. Students
will become familiar with various methods of literature search, data collection, data analysis, as well as the ethical questions of scientific
research. Students will be introduced to various types of scientific works, including rules and requirements of scientific communication.
A session will be dedicated to the special requirements of writing a thesis. Emphasis will be laid on practice: in the seminars students
should put into practice what they have learned in the lectures, based on their own research work.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Students will be required to perform some tasks related to their own research topic. The midsemester grade will be based on the successful
completion of the following tasks:
- literature search
- write a research plan
- prepare a questionnaire
- analyze data
- critically evaluate data, draw conclusions
- present results (oral and written format)
Making up for missed classes
Students can make up for absences by completing the tasks and home assignments of each class.
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture materials are available at the website of the Department of Pharmacognosy.
- Notes
- Recommended literature
Turabian K. L. (2010): A Manual for Writers of Research Papers, Theses, and Dissertations. Chicago Style for Students &
Researchers. 8th edition. The University of Chicago Press. Chicago and London, pp. 448.
Lectures
1 Concept, process and strategies of scientific research. Organising research projects.
Dr. Farkas Ágnes
2 Literature search
Dr. Farkas Ágnes
3 Writing a research plan. Designing experiments.
Dr. Farkas Ágnes
4 Methods of data collection. Questionnaires.
Dr. Farkas Ágnes
5 Data processing, data analysis.
Dr. Farkas Ágnes
6 Evaluation of data.
Dr. Farkas Ágnes
7 The role of informatics in scientific research.
Dr. Farkas Ágnes
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150
8 The role of informatics in scientific research.
Dr. Farkas Ágnes
9 Ethical questions of scientific research.
Dr. Farkas Ágnes
10 Animal studies. Clinical studies.
Dr. Farkas Ágnes
11 Scientific communication. Types of scientific works. Metrics of scientific achievement.
Dr. Farkas Ágnes
12 Rules and requirements in scientific communication.
Dr. Farkas Ágnes
13 Writing applications for scholarships and research grants.
Dr. Farkas Ágnes
14 Scientific co-operations. Scene and institutions of science in Hungary.
Dr. Farkas Ágnes
Practices
Seminars
1 Literature search in the field of the student’s own research I.
Dr. Farkas Ágnes
2 Literature search in the field of the student’s own research II.
Dr. Farkas Ágnes
3 Preparing a research plan based on the student’s own research objectives.
Dr. Farkas Ágnes
4 Preparing a questionnaire
Dr. Farkas Ágnes
5 Evaluation of data from the student’s research project I.
Dr. Farkas Ágnes
6 Evaluation of data from the student’s research project II.
Dr. Farkas Ágnes
7 Practice of scientific communication I.
Dr. Farkas Ágnes
8 Practice of scientific communication II.
Dr. Farkas Ágnes
9 Practice of scientific communication III.
Dr. Farkas Ágnes
10 Practice of scientific communication IV.
Dr. Farkas Ágnes
11 Practice of scientific communication V.
Dr. Farkas Ágnes
12 Practice of scientific communication VI.
Dr. Farkas Ágnes
13 Practice of writing an application for a scholarship I.
Dr. Farkas Ágnes
14 Practice of writing an application for a research project II.
Dr. Farkas Ágnes
Exam topics/questions
1. Research plan.
2. Methods of data collection.
3. Questionnaires.
4. Methods of literature search.
5. Methods of data analysis.
6. Critical evaluation of data.
7. Ethical questions of scientific research.
8. Animal studies. Clinical studies.
9. Scientific writing: types, rules and requirements.
10. References, bibliography.
11. Scene and institutions of science in Hungary.
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Participants
Dr. Farkas Ágnes (DKQUBQ)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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152
OPE-DM2-T DEMONSTRATOR ACTIVITY 2
Course director: DR. LÁSZLÓ JÓZSEF CZOPF, associate professor
1st Department of Internal Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ both semesters ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OPE-DM1-T completed
Topic
This course gives support and acknowledgement for students performing documented and successful supervised teaching activities and
taking an active part in organizing courses.
The subjects can be taken up in eight semesters (in a total value of 16 credits).
Conditions for acceptance of the semester
Students have to register every semester as demonstrators, should provide proof of previous demonstrator activity, and the semester will
be signed on the basis of at least 24 hours of teaching or organizatory activity. The grades will be given according to the Code of
Demonstrators with additional requirements, that you can reach using the following links: Code of Demonstrator Students:
https://docs.google.com/document/d/1xkkyeRdZcDphnqWEkpON0SQf34MpBBJqogG09foI8Rw/edit?usp=sharing
Faculty Home Page of the Circle of Demonstrator Students (DDK):
http://aok.pte.hu/en/egyseg/almenu/980/339
Mid-term exams
At least two midsemester tests should be successfully completed to pass.
Making up for missed classes
There are no absences accepted from the 24 hours demonstrator activity.
Reading material
- Obligatory literature
- Literature developed by the Department
..
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
The topics of the tests depend on the specific course of the demonstrator activity.
Participants
Dr. Czopf László József (BAVD1M), Dr. Koppán Ágnes Judit (ZAEQDO), Dr. Sebők Judit (GLM10L), Dr. Tamás Andrea (F7QM8G),
Dr. Ujvári Balázs (EN1LY9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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153
OPE-GMO-T MODELLING THE STRUCTURE AND INTERACTIONS OF BIOACTIVE MOLECULES
Course director: DR. SÁNDOR KUNSÁGI-MÁTÉ, associate professor
Department of Organic and Pharmacological Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ both semesters ▪ recommended semester: 4
Number of hours/semester: 17 lectures + 11 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 2 – 12 Prerequisites: -
Topic
Students will get deeper insights into the mechanisms of drug interactions at molecular level applying fundamental molecular modelling
methods. Further answering the scientific questions students will get skills to perform high quality figures and schemes of molecules and
molecular interactions to present their results and presentation content in lectures, diploma works or thesises. In this course the basic
examination methods of theoretical chemistry will be discussed by the practical point of view in the frame of following subtopics:
Methods of molecular modelling. Description of the forcefield, semiempirical, ab initio and density functional methods, advantages and
disadvantages. Discovering the balance between the model ant the calculation methods. The algorithm of the choice of appropriate model
and calculation method. Short description of the basic rules and mathematical background of theoretical chemistry. calculation of the
electronic structure of atoms and molecules. Calculation the equilibrium conformations of molecules, the role of the entropy in the
interactions of bioactive molecules and its calculation. Description of the correlation between the reactivity and the temperature.
Examples at molecular level. Considering the molecular environment: explicit and implicit methods. Interesting examples and
applications in pharmacy.
Conditions for acceptance of the semester
There is no possibility to make up for a missed lecture
Mid-term exams
Two tests, each above 60 % is required for acceptance
Making up for missed classes
Upto 15% is allowed, electronical material is available
Reading material
- Obligatory literature
P.W. Atkins: Physical Chemistry
- Literature developed by the Department
Slides and notes of all lectures are available electronically. All topics discussed will be associated with papers published recently.
Those papers together with the related doctoral dissertations in English will also be offered to support the teaching.
- Notes
Slides and Summaries of lectures are available electronically
- Recommended literature
Jensen_F.-Introduction_to_Computational_Chemistry_(2007)
Scientific papers, list will be given during the lectures
Lectures
1 1 lecture Experimental results raise the necessity of quantum-chemical description of the structure of materials. Quantitization
and related quantities (energy, momentum, spin). Simple mathematical descriptions.
Dr. Kunsági-Máté Sándor
2 1 lecture Experimental results raise the necessity of quantum-chemical description of the structure of materials. Quantitization
and related quantities (energy, momentum, spin). Simple mathematical descriptions.
Dr. Kunsági-Máté Sándor
3 2 lecture Axiomatic description of the quantum theory. Atomic unit system. Overview on the exact and approximative solutions
of the time - independent Schrödinger equation.
Dr. Kunsági-Máté Sándor
4 2 lecture Axiomatic description of the quantum theory. Atomic unit system. Overview on the exact and approximative solutions
of the time - independent Schrödinger equation.
Dr. Kunsági-Máté Sándor
5 3 lecture Approximative solutions: the molecular mechanics methods.
Dr. Kunsági-Máté Sándor
6 3 lecture Approximative solutions: the molecular mechanics methods.
Dr. Kunsági-Máté Sándor
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154
7 4 lecture Semi - empirical methods, advantages and disadvantages.
Dr. Kunsági-Máté Sándor
9 5 lecture Conformation analysis, energy minimization algorithms.
Dr. Kunsági-Máté Sándor
11 6 lecture Electronic structure of molecules. The chemical bonds, tipes of bonds. The structure of molecules, stereochemistry.
Dr. Kunsági-Máté Sándor
13 7 lecture Modelling in comparison with the experiments, calculation of the enthalpy, entropy and their appropriate experimental
values.
Dr. Kunsági-Máté Sándor
15 8 lecture Molecular symmetry, point groups and the symmetry of molecular vibrations.
Dr. Kunsági-Máté Sándor
17 9 lecture Interactions of the primycin, ergosterol and oleic acid as plasma membrane unit.
Dr. Kunsági-Máté Sándor
19 10 lecture Modelling the interactions of bioactive molecules with molecular containers in accordance with molecular packing of
drugs.
Dr. Kunsági-Máté Sándor
21 11 lecture Quantum - chemical background of the rules in atomic and molecular spectroscopy. Rules of Raman and Infrared
transitions and their relationship with the molecular symmetry.
Dr. Kunsági-Máté Sándor
23 12 lecture Effective calculation methods to consider the molecular environment: Onsager-model, Polarizable Continuum Model
Dr. Kunsági-Máté Sándor
25 13 lecture Examples: simple chemical reactions, calculation of the stability weak molecular complexes, conformation analysis.
Dr. Kunsági-Máté Sándor
27 14 lecture Examples: modelling the systems possessing high symmetry and infinite volume. Crystals and polymers.
Dr. Kunsági-Máté Sándor
Practices
4 4 practice : Geometry optimization and conformation analysis. Energy minimization algorythm mostly used in geometry
optimization practice.
Dr. Kunsági-Máté Sándor
5 5 practice: Calculation of the static potential energy surfaces of chemical reactions. Methods to determine the transition states
associated to the chemical reactions. Activation energy and activation free enthalpy.
Dr. Kunsági-Máté Sándor
6 6 practice Molecular dynamics methods, Monte-Carlo method and the Langevin model. The implicite consideration of the
molecular environment.
Dr. Kunsági-Máté Sándor
7 7 practice Modelling the elementary chemical reactions. Calculation of molecular dynamics. Determination of the rection rate
using direct trajectory method.
Dr. Kunsági-Máté Sándor
8 8 practice Methods for consideration of the solvents: the Onsager-model, and the Polarizable Continuum Model, PCM. Explicit
consideration of the solvent molecules. The TIP3P model.
Dr. Kunsági-Máté Sándor
9 9 practice Calculation of molecular parameters have significant importance in the practice. The QSAR and the molecular
similarity - analysis.
Dr. Kunsági-Máté Sándor
10 10 practice Examples: conformation analysis, bong length, bond angle and dihedral angles. The bipyridile and thionine molecules.
Calixarenes and stereoisomers. Importance of hydrogen bonds in the stability of molecular geometries.
Dr. Kunsági-Máté Sándor
11 11 practice Examples: interactions of molecules. Calculation of the host - guest interactions, calculations of interactions of
calixarenes with neutral molecules based on pi-pi interactions.
Dr. Kunsági-Máté Sándor
12 12 practice Examples : elementary dissociation reactions: dissociation of asymmetric olefines. Effect of melecular environment
on the reaction rate.
Dr. Kunsági-Máté Sándor
13 13 practice Examples: Interaction of Primycin and oleic acid. Calculation of the interaction energy in system possessing large
numbers of electrons.
Dr. Kunsági-Máté Sándor
14 14 practice E+xamples: dynamic processes: modelling the crystal growth.
Dr. Kunsági-Máté Sándor
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155
Seminars
Exam topics/questions
Methods of molecular modelling. Description of the forcefield, semiempirical, ab initio and density functional methods, avantages and
disadvantages. The balance between the model ant the calculation methods. The algorithm of the choice of appropriate model and
calculation method.Short description of the basic rules and mathematical background of theoretical chemistry. calculation of the
electronic structure of atoms and molecules. Calculation the equilibrium conformations of molecules, the role of the entropy in the
interactions of bioactive molecules and its calculation. Description of the correlation between the reactivity and the temperature.
Examples at moecular level. Considering the molecular environment: explicit and implicit methods. Interesting examples and
applications in pharmacy.
Participants
Dr. Kunsági-Máté Sándor (UYZM2Q)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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156
OPE-SME-T SPECTROMETRIC IDENTIFICATION OF ORGANIC COMPOUNDS
Course director: DR. CECILIA PÁPAY-SÁR, associate professor
Department of Organic and Pharmacological Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours
Course headcount limitations (min.-max.): 2 – 10 Prerequisites: OPA-S1E-T completed
Topic
The aim of this course is to introduce the students how to identify organic compounds from the complementary information afforded by
three types of spectra: infrared, mass and NMR.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
The student who has been absent from more than 25 % of the classes cannot be granted to entry of exam.
Making up for missed classes
Students can personally consult with the lecturer.
Reading material
- Obligatory literature
Silverstein, R.M., Webster, F.X., Kiemle, D.: Spectrometric Identification of Organic Compounds, John Wiley and Sons, 2005.
- Literature developed by the Department
The ppt slides are uploaded to Neptun Meet Street.
- Notes
- Recommended literature
Lectures
Practices
Seminars
1 Infrared Spectroscopy: Introduction, theory, instrumentation, interpretation of spectra
Pápayné Dr. Sár Cecilia
2 Infrared Spectroscopy: Introduction, theory, instrumentation, interpretation of spectra
Pápayné Dr. Sár Cecilia
3 Infrared Spectroscopy: Characteristic group absorptions of organic molecules
Pápayné Dr. Sár Cecilia
4 Infrared Spectroscopy: Characteristic group absorptions of organic molecules
Pápayné Dr. Sár Cecilia
5 Infrared Spectroscopy: Solving problems
Pápayné Dr. Sár Cecilia
6 Infrared Spectroscopy: Solving problems
Pápayné Dr. Sár Cecilia
7 Proton Magnetic Resonance Spectrometry (1H NMR): Introduction, theory, instrumentation
Pápayné Dr. Sár Cecilia
8 Proton Magnetic Resonance Spectrometry (1H NMR): Introduction, theory, instrumentation
Pápayné Dr. Sár Cecilia
9 1H NMR: Chemical shift, simple spin coupling
Pápayné Dr. Sár Cecilia
10 1H NMR: Chemical shift, simple spin coupling
Pápayné Dr. Sár Cecilia
11 1H NMR: Protons on heteroatoms, chemical shift equivalence and magnetic equivalence, effects of a chiral center
Pápayné Dr. Sár Cecilia
12 1H NMR: Protons on heteroatoms, chemical shift equivalence and magnetic equivalence, effects of a chiral center
Pápayné Dr. Sár Cecilia
13 13 C NMR Spectroscopy: Interpretation of 13 C spectra. The principles of MRI
Pápayné Dr. Sár Cecilia
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157
14 1H NMR and 13 C NMR: Solving problems
Pápayné Dr. Sár Cecilia
15 Mass Spectrometry: Mass spectrometer parts, ionization processes
Dr. Kálai Tamás
16 Mass Spectrometry: Mass spectrometer parts, ionization processes
Dr. Kálai Tamás
17 Mass Spectrometry: Appearance of the mass spectrum, mass spectra of classes of organic compounds
Dr. Kálai Tamás
18 Mass Spectrometry: Appearance of the mass spectrum, mass spectra of classes of organic compounds
Dr. Kálai Tamás
19 Mass Spectrometry: Interpretation of the mass spectrum through examples
Dr. Kálai Tamás
20 Mass Spectrometry: Interpretation of the mass spectrum through examples
Dr. Kálai Tamás
21 Summary of spectroscopic methods: identification of organic molecules from IR, NMR and mass spectra
Pápayné Dr. Sár Cecilia
22 Summary of spectroscopic methods: identification of organic molecules from IR, NMR and mass spectra
Pápayné Dr. Sár Cecilia
23 Summary of spectroscopic methods: identification of organic molecules from IR, NMR and mass spectra
Pápayné Dr. Sár Cecilia
24 Evaluation, written test
Pápayné Dr. Sár Cecilia
Exam topics/questions
Infrared Spectroscopy: theory, instrumentation, interpretation of spectra, chacteristic group absorptions of organic molecules.
Proton Magnetic Resonance Spectrometry (1H NMR): theory, instrumentation, chemical shift, simple spin coupling, protons on
heteroatoms, chemical shift equivalence and magnetic equivalence, effects of a chiral center.
Mass Spectrometry: mass spectrometer parts, ionization processes, appearance of the mass spectrum, mass spectra of classes of organic
compounds.
Identification of simple organic molecules from IR, NMR and mass spectra.
Participants
Dr. Kálai Tamás (BDF5M9), Pápayné Dr. Sár Cecilia (BTYFJX)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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158
OPE-HL2-T ADVANCED PHYSIOLOGY 2
Course director: DR. TAMÁS OLLMANN, assistant professor
Institute of Physiology [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 98 Prerequisites: -
Topic
Discussion of physiological topics, that not belong to the core subject (based on real examples and case studies). The aim of the subject
is to understand the deep, advanced physiological knowledge and complete the core subject. That develops the problem-solving skills
necessary in the clinical practice and/or during scientific research. Furthermore, it can help to understand another subjects
(pathophysiology, pharmacology) based on physiology as well. The course can be useful for dentistry and pharmacy students as well,
since numerous topics are realted to dentistry or pharmacy as well. The course can contribute to the practical application of evidence
based medicine, as well as to interpret the (sometimes contradictory) scientific literature. Topics of the second semester: endocrine
system, nervous system and sensory organs.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Writing of case study, online test.
Making up for missed classes
Not necessary, but it is possible in another language.
Reading material
- Obligatory literature
- Literature developed by the Department
The slides will be available on PotePedia.
- Notes
- Recommended literature
Guyton and Hall: Textbook of Medical Physiology
Costanzo: Physiology Cases and Problems (Board Review Series)
Carroll: Problem-Based Physiology
Lectures
1 Endocrine system. Hypophysis. The importance of balance.
Dr. Ollmann Tamás
2 Adrenal cortex. The unconscious cushingoid patient.
Dr. Ollmann Tamás
3 Adrenal medulla. Autonomic nervous system. The patient with too much stress.
Dr. Ollmann Tamás
4 Male sexual functions. The regulation of sexual behaviour. Differences from the average.
Dr. Ollmann Tamás
5 Female sexual functions. Birth. The mysterious symptoms of a young lady.
Dr. Ollmann Tamás
6 Thyroid gland. The case of the hyperactive child.
Dr. Ollmann Tamás
7 Calcium and phosphate. Physiology of the bone. The patient wiht muscle spasm.
Dr. Ollmann Tamás
8 Blood sugar level and diabetes. What should we take into consideration?
Dr. Ollmann Tamás
9 General properties of the nervous system. Peripheral nerv. Reflexes. Are we just a neural network?
Dr. Ollmann Tamás
10 Pyramidal system. From decortication to the spinal shock. The patient with stroke.
Dr. Ollmann Tamás
11 Extrapyramidal system. Parkinson, or not? Deep brain stimulation.
Dr. Ollmann Tamás
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12 The cerebellum and being drunk.
Dr. Ollmann Tamás
13 The somatosensory system. How can we relieve pain?
Dr. Ollmann Tamás
14 The eye. Optics. The patient with blurred vision.
Dr. Ollmann Tamás
15 The retina and the visual pathway. Visual field defects.
Dr. Ollmann Tamás
16 The ear. The patient with vertigo.
Dr. Ollmann Tamás
17 Smell and taste. The patient who cannot recognize smells.
Dr. Ollmann Tamás
18 EEG, sleep. The doctor’s epileptic seizure.
Dr. Ollmann Tamás
19 Hypothalamus. Size doesn’t matter.
Dr. Ollmann Tamás
20 Limbic system. Motivations. Emotions. Play and addiction.
Dr. Ollmann Tamás
21 Monoamines. Schizophrenia. Autism and gut flora. The difficulties with pshychiatric medication.
Dr. Ollmann Tamás
22 Learning and memory. The patient wiht amnesia.
Dr. Ollmann Tamás
23 The functions of different areas of the brain. Effects of brain injury on personality and speech.
Dr. Ollmann Tamás
24 Brain research: from the rodents to the human. Addiction. The life of a clinician, scientific researcher and university lecturer.
Complex case study.
Dr. Ollmann Tamás
Practices
Seminars
Exam topics/questions
The topics of the lectures.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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160
OPE-TIZ-T CENTRAL REGULATION OF FEEDING AND METABOLISM. NEW APPROACHES
Course director: DR. ZOLTÁN KARÁDI, emeritus professor
Institute of Physiology [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 2 – 25
Prerequisites: OPO-AI2-T completed + OPO-H1E-T completed + OPO-G1B-T parallel
Topic
The high incidence and costs of eating and metabolic disorders make it indispensable to experimentally test new theoretical
considerations, and to employ their conclusive results in basically new clinical protocols. Students at early stage of their studies are, thus,
encouraged to familiarize with new theoretical aspects and experimental findings.
Neural and humoral mechanisms in the central feeding control and metabolic regulation. Body weight control in health and disease.
Peripheral and central taste information processing; gustation in the central regulation of food and fluid intake. Obesity, diabetes mellitus
and the metabolic syndrome: New interpretations.
Conditions for acceptance of the semester
According to general regulations
Mid-term exams
Individual oral mid-semester test.
Making up for missed classes
Individually discussed
Reading material
- Obligatory literature
Guyton & Hall: Textbook of Medical Physiology, Saunders
- Literature developed by the Department
- Notes
- Recommended literature
Williams and Pickup: Handbook of Diabetes, Blackwell
Doty: Handbook of Olfaction and Gustation, Marcel Dekker
Lectures
1 Physiological significance of food and fluid intake, and metabolism. Homeostasis, motivation.
Dr. Karádi Zoltán
2 Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways,
neuropeptides. I
Dr. Karádi Zoltán
3 Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways,
neuropeptides. II
Dr. Karádi Zoltán
4 Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways,
neuropeptides. III
Dr. Karádi Zoltán
5 Exogenous chemosensory modalities. Physiologic roles of gustation.
Dr. Karádi Zoltán
6 Central taste pathways, „labeled lines”, neurons.
Dr. Karádi Zoltán
7 Taste preference, taste aversion, palatability, flavour.
Dr. Karádi Zoltán
8 The glucose-monitoring (GM) neural network. I
Dr. Karádi Zoltán
9 The glucose-monitoring (GM) neural network. II
Dr. Karádi Zoltán
10 Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. I
Dr. Karádi Zoltán
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161
11 Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. II
Dr. Karádi Zoltán
12 Feeding and metabolic disorders: disturbance of the GM system?
Dr. Karádi Zoltán
Practices
Seminars
Exam topics/questions
1. Feeding (hunger) and satiety centers; feeding (hunger) and satiety neural pathways.
2. Orexigenic and anorexigenic neuromodulator factors (list up at least 3 of each).
3. The two major neuron types of the hypothalamic arcuate nucleus (with respect to feeding); their modulation by insulin, leptin, and
ghrelin.
4. Key structures of the central glucose-monitoring neuronal network (list up at least 4 of them).
5. Consequences of selective destruction of central GM neurons (name of the toxic agent, and its effects).
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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162
ATT5-T PHYSICAL EDUCATION 5
Course director: DR. ISTVÁN KARSAI, assistant professor
UP MS Sports Facilities [email protected]
0 credit ▪ signature ▪ Optional subject ▪ both semesters ▪ recommended semester: 5
Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 2 – 50 Prerequisites: ATT4-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
This subject provides theoretical and practical information for the students to maintain and improve their physical condition and helps to
deepen the knowledge in the field of healthy lifestyle.
Theoretical and practical knowledge during different types of exercises e.g. how to improve endurance, muscle force, motor skills and
how to prevent the body from injuries.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Making up for missed classes
We provide opportunities to attend extra lessons in the first week of the exam period in that case the requirements are not fulfilled till the
end of the teaching weeks with agreement of the PE Teacher.
Reading material
- Obligatory literature
- Literature developed by the Department
Not available.
- Notes
- Recommended literature
Lectures
Practices
1-28 For the list of actual courses please turn to the end of document for the obligatory subjects of the 1-2nd semester
Seminars
Exam topics/questions
Participants
Farkas György (CL1MIY), Lipcsik Zoltán (EGE1AE), Németh Attila Miklós (EXB7TD), Téczely Tamás (P0OP8M)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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163
OPF-GKG-T GAS CHROMATOGRAPHY
Course director: DR. VIKTÓRIA POÓR, assistant professor
Institute of Bioanalysis [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 8 lectures + 4 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 4 – 15 Prerequisites: OPA-M1E-T completed
Topic
Key Topics
-practical theory about Gas Chromatography
-how to select and use the carrier gas
-various injection techniques and when to use each
-how to select a GC column
-the operation and selection of an appropriate GC detector
-how to write measuring methods
-how to undertake data analysis
-sampling techniques for GC
-strategies for method development
-introduction to GC & MS advanced techniques
-applications (pharmaceutical application)
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
1 test during the semester
1 oral presentation (based on research articles on the field of pharmaceutical apllication)
Making up for missed classes
There is no possibility for retake
Reading material
- Obligatory literature
Modern Analytical Cheymistry,David Harvey
- Literature developed by the Department
www.aok.pte.hu/bioanalitika
- Notes
- Recommended literature
Lectures
1 practical theory about Gas Chromatography
Dr. Poór Viktória
2 how to select and use the carrier gas
-various injection techniques and when to use each
Dr. Poór Viktória
3 how to select a GC column
-the operation and selection of an appropriate GC detector
Dr. Poór Viktória
4 strategies for method development
Dr. Poór Viktória
5 introduction to GC & MS advanced techniques
Dr. Poór Viktória
6 introduction to GC & MS advanced techniques
Dr. Poór Viktória
7 how to write measuring methods
Dr. Poór Viktória
8 how to undertake data analysis
Dr. Poór Viktória
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164
Practices
1 GC practice 1
Dr. Poór Viktória
2 GC practice 2
Dr. Poór Viktória
3 GC-MS 1.
Dr. Poór Viktória
4 GC-MS 2.
Dr. Poór Viktória
Seminars
Exam topics/questions
1 test during the semester
1 oral presentation (based on research articles on the field of pharmaceutical apllication)
Participants
Dr. Poór Viktória (MJELTX)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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165
OPF-GLK-T BIOINORGANIC CHEMISTRY FOR PHARMACY STUDENTS
Course director: DR. ZSUZSANNA ROZMER, assistant professor
Department of Pharmaceutical Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 5 – 15
Prerequisites: OPA-T2E-T completed + OPA-S2E-T completed + OPO-GE2-T parallel
Topic
We will provide an overview in this block about bioinorganic topics of chemistry, regarding the role of the different elements in medicinal
and pharmaceutical chemistry. Our aim is to offer a concise knowledge also about bioinorganic relations on medical contrast agents like
X-ray, tomographic, MR and ultrasound contrast agents. The use of radionuclids in diagnostical methods will be discussed too.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Students will have to write a written test at the end of the semester.
Making up for missed classes
In case of absences the students must follow up with self-education!
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture notes provided by the lecturer.
- Notes
- Recommended literature
Lectures
1 Introduction, The biological importance of non-metals and metals.
Dr. Huber Imre
2 An overview of the elements.
Dr. Huber Imre
3 Rtg-contrast agents.
Dr. Huber Imre
4 Watersoluble nephrothrop Rtg-contrast agents with high osmolality.
Dr. Huber Imre
5 Watersoluble nephrothrop Rtg-contrast agents with low osmolality.
Dr. Huber Imre
6 Watersoluble hepatothrop Rtg-contrast agents.
Dr. Huber Imre
7 Water-insoluble Rtg-contrast agents.
Dr. Huber Imre
8 Contrast agents for MRI.
Dr. Huber Imre
9 Contrast agents for CT.
Dr. Huber Imre
10 Contrast agents for ultrasound.
Dr. Huber Imre
11 Radioactive diagnostics (radionuclids).
Dr. Huber Imre
12 Platinum comlexes in medicin. Chelation therapy.
Dr. Huber Imre
13 Bisphosphonates in medicin.
Dr. Huber Imre
14 Geometry of complexes. Closing written test.
Dr. Huber Imre
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Practices
Seminars
Exam topics/questions
These are listed in the lecture notebook written by the lecturer. These notes are about the different questions of this field with the
corresponding answers, parallely.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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167
OPF-GMT-T DRUG METABOLISM AND DRUG TOXICITY
Course director: DR. ATTILA ALMÁSI, assistant professor
Department of Pharmaceutical Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 3 – 50 Prerequisites: OPO-G1B-T completed
Topic
On the seminaries of this facultative course the molecular background and the influenceability of the side and toxic effects of different
drugs are aimed, during the drug absorption, drug transformation and drug elimination.
During the course, the metabolic activation and transformation of the environmental carcinogens are to be discussed.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
In the end of the semester the students write an end-semester test. The test is evaluated in percentage and the final grade is to be established
based on this result. The result of the test should be above 60%.
Making up for missed classes
The replacement of the missed test is required.
Reading material
- Obligatory literature
- Literature developed by the Department
Slides of the lectures.
- Notes
- Recommended literature
Lectures
1 Introduction. The toxicological aspects of drug metabolism.
Dr. Almási Attila
2 Characteristics of xenobiotics in the body
Dr. Almási Attila
3 Metabolic transformation I. Phase I. or functionalisation reactions 1 (CYP enzymes).
Dr. Almási Attila
4 Metabolic transformations II. Phase I. or functionalisation reactions 2 (FAD enzymes and non microsomal transformations).
Dr. Almási Attila
5 Metabolic transformations III. Phase II. or conjugation reactions 1 ( glucuronic acid conjugation, sulphate conjugation).
Dr. Almási Attila
6 Metabolic transformations IV. Phase II. or conjugation reactions 2 ( amino acid conjugation, acetylation, methylation, gluthatione
conjugation).
Dr. Almási Attila
7 Phase III. transformations (transporters), general molecular mechanism of drug toxicity.
Dr. Almási Attila
8 Biotransformation and the toxic effects of the paracetamol. Factors influence the toxicity of the paracetamol.
Dr. Almási Attila
9 Toxicity of the non-steroid antiinflammatory drugs (NSAIDs). Hepatotoxic effect of the diclofenac.
Dr. Almási Attila
10 Toxicity of the troglitazone. Sulfonamide hypersensitivity.
Dr. Almási Attila
11 Chemical carcinogenesis I., Definition, cell division, environmental carcinogens, chemical carcinogenesis.
Dr. Almási Attila
12 Chemical carcinogenesis II., Structure and metabolic activation of environmental carcinogens.
Dr. Almási Attila
13 Metabolic differences between species, genetic polymorphism.
Dr. Almási Attila
14 Changes in drug metabolism during pregnancy and at aged people.
Dr. Almási Attila
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Practices
Seminars
Exam topics/questions
Based on the announced thesis list.
Participants
Dr. Almási Attila (KJ5MBZ)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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169
OPF-HKG-T INTERFACIAL CHEMISTRY IN PHARMACEUTICAL TECHNOLOGY
Course director: DR. SZILÁRD PÁL, assistant professor
Institute of Pharmaceutical Technology and Biopharmacy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – 30
Prerequisites: OPA-PC2-T completed + OPA-KD1-T completed + OPG-C1E-T parallel
Topic
Based on the earlier colloid and physical chemistry studies, the course deals with the colloid systems, which are widely used in
pharmaceutical technology. After a short summary of general colloid and interfacial chemistry, we discuss about the most important
contemporaneous medicines and the modern pharmaceutics.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Participation on the seminars - accepted work reports - accepted written assessments Students have to write an end-semester assessment
from the lectures at acceptance level of 60%.
Making up for missed classes
Students must fulfill requirements determined by the Code of Studies and Examinations. Student has to make up the missed lectures and
do work reports.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Duncan J. Shaw: Introduction to colloid and surface chemistry (Elsevier, 2013)
Vijay Kumar Thakur and Manju Kumari Thakur: Handbook of Polymers for Pharmaceutical Technologies (Wiley, 2015)
Tharwat F. Tadros: Colloid Stability and Application in Pharmacy ()
Lectures
1 Introduction to Pharmaceutical Technology
Vörös-Horváth Barbara
2 Introduction to Pharmaceutical Technology
Vörös-Horváth Barbara
3 Interfacial chemistry basics
Vörös-Horváth Barbara
4 Interfacial chemistry basics
Vörös-Horváth Barbara
5 Sols and suspensions in pharmaceutical technology
Vörös-Horváth Barbara
6 Sols and suspensions in pharmaceutical technology
Vörös-Horváth Barbara
7 Sols and suspensions in magistral medicines
Vörös-Horváth Barbara
8 Sols and suspensions in magistral medicines
Vörös-Horváth Barbara
9 Emulsions in pharmaceutical technology
Vörös-Horváth Barbara
10 Emulsions in pharmaceutical technology
Vörös-Horváth Barbara
11 Emulsions in magistral medicines
Vörös-Horváth Barbara
12 Emulsions in magistral medicines
Vörös-Horváth Barbara
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13 Pickering emulsions in pharmacy
Vörös-Horváth Barbara
14 Pickering emulsions in pharmacy
Vörös-Horváth Barbara
15 Polymers in pharmaceutical technology I.
Vörös-Horváth Barbara
16 Polymers in pharmaceutical technology I.
Vörös-Horváth Barbara
17 Polymers in pharmaceutical technology I.
Vörös-Horváth Barbara
18 Polymers in pharmaceutical technology I.
Vörös-Horváth Barbara
19 Solid dispersions in pharmaceutical technology
Vörös-Horváth Barbara
20 Solid dispersions in pharmaceutical technology
Vörös-Horváth Barbara
21 Aerosols and foams in pharmaceutical technology
Vörös-Horváth Barbara
22 Aerosols and foams in pharmaceutical technology
Vörös-Horváth Barbara
23 Associations colloids in pharmaceutical technology
Vörös-Horváth Barbara
24 Associations colloids in pharmaceutical technology
Vörös-Horváth Barbara
25 Pharmaceutical nanotechnology
Vörös-Horváth Barbara
26 Pharmaceutical nanotechnology
Vörös-Horváth Barbara
27 Written test
Dr. Pál Szilárd
28 Written test
Dr. Pál Szilárd
Practices
Seminars
Exam topics/questions
Students can get the test topics in the institute or download the from website of the institute.
Participants
Dr. Pál Szilárd (FYF5E9), Vörös-Horváth Barbara (QR6NGM)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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171
OPF-HVS-T SYNTHESIS OF HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN THERAPY
Course director: DR. TAMÁS KÁLAI, professor
Department of Pharmaceutical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – 12 Prerequisites: OPA-S1E-T completed
Topic
Heterocyclic chemistry is an important subdivision of organic chemistry, as 70% of all medicines are heterocyclic compound or contains
a heterocyclic moiety. This course will give an introduction to, and the summary of, the most important principles and ideas of
heterocyclic chemistry. This course partially re-calls the knowledge of Organic chemisty 1 and Organic chemistry 2 course, discusses
those details which were not reflected on, because of time shortage and supports to evaluate the pharmacological chemistry subject.
-Electronic structure of heterocycles
-Nomenclature of heterocyclic compounds
-Main synthetic routes to heterocyclic compounds, Saturated heterocycles, occurence of heterocycles
-Three and four membered heterocycles (synthesis, reactions, occurence)
-The pyrrole and indole (synthesis, reactions, occurence)
-Furan, thiophene and their benzo derivatives.
-Five membered heterocycles with two or more heteroatoms: imidazole, oxazole, thiazole
-Pyrazole, isoxazole, isothiazole
-I. st test, Six-membered heterocycles with one oxygen heteroatom (piranes, chromones, flavones and coumarins)
-Six membered heterocycles with one nitrogen atom (pyridine, quinoline, isoquinoline)
-Six membered heterocycles with two or more heteroatoms (purine, diazines, triazines etc.)
-Seven membered heterocyclic chemistry
-Heterocycles in supramolecular chemitry
-Heterocyclic compounds in organic snthesis
-II nd test, short presntation on a paper on heterocyclic chemistry
-Evaluation
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
The students write two tests, at the middle of the semester and at the end of the semester. Every student have a chance to make a
presentation based on a heterocyclic chemistry paper for an extra grade.
Making up for missed classes
Personal communication. The english program student might visit the paralell hungarian course to catch up the main reaction equations.
Reading material
- Obligatory literature
Li, J. J. Hetrocyclic chemistry in Drug Discovery, Wiley
- Literature developed by the Department
Slides will be given to students as a ppt or pdf files.
- Notes
Joule, J. J.; Mills, K. Heterocyclic chemistry at a Glance. (Wiley)
- Recommended literature
Li, J. J. Top 10 drugs Oxfors University Press
Lectures
Practices
Seminars
1 Electronic structure of heterocycles, nomenclature of heterocycles
Dr. Kálai Tamás
2 Occurence of heterocyclic compounds
Dr. Kálai Tamás
3 Synthesis of heterocycles
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Dr. Kálai Tamás
4 Common reaction types in heterocyclic chemistry
Dr. Kálai Tamás
5 Tautomerism in heterocyclic chemistry
Dr. Kálai Tamás
6 Saturated heterocycles
Dr. Kálai Tamás
7 Three and four membered heterocycles, beta lactams
Dr. Kálai Tamás
8 Three and four-membered heterocycles and beta lactams
Dr. Kálai Tamás
9 Synthesis of pyrroles and porfirine ring containing compounds
Dr. Kálai Tamás
10 Synthesis of indoles, main reactions of indoles.
Dr. Kálai Tamás
11 Furans and thiophenes
Dr. Kálai Tamás
12 Thiophenes and benzothiophenes
Dr. Kálai Tamás
13 1,2-azoles, their synthesis, reactions and their occurence in drugs
Dr. Kálai Tamás
14 1,3-azoles, their synthesis, reactions, occurence in drugs
Dr. Kálai Tamás
15 1st test (generral feature of heterocyclic compounds (3-, 4-, 5-membered heterocycles)
Dr. Kálai Tamás
16 Six membered heterocycles containing oxygen heteroatom
Dr. Kálai Tamás
17 Pyridines (synthesis, reactions, occurence in drugs and biomolecules)
Dr. Kálai Tamás
18 Quinolines, isoquinolines (synthesis, reactions, occurence in drugs)
Dr. Kálai Tamás
19 Synthesis of pyrimidines and their occurence in medicines
Dr. Kálai Tamás
20 Synthesis and reactions of 1,2- and 1,4-diazines
Dr. Kálai Tamás
21 Synthesis and reactions of triazines and purines
Dr. Kálai Tamás
22 Heterocycles of life and death
Dr. Kálai Tamás
23 Seven membered heterocycles their occurence, synthesis, applications in therapy
Dr. Kálai Tamás
24 IInd test, short presentations on papers on heterocyclic chemistry, evaluation
Dr. Kálai Tamás
25 Heterocycles in supramolecular chemistry
Dr. Kálai Tamás
26 Heterocycles in organic synthesis
Dr. Kálai Tamás
27 2nd test (6- and 7-membered heterocycles)
Dr. Kálai Tamás
28 Short presentations, evaluations
Dr. Kálai Tamás
Exam topics/questions
-Electronic structure of heterocycles
-Nomenclature of heterocyclic compounds
-Main synthetic routes to heterocyclic compounds
-Saturated heterocycles
-Three and four membered heterocycles (synthesis, reactions, occurence)
-The pyrrole and indole (synthesis, reactions, occurence)
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-Furan, thiophene and their benzo derivatives.
-Five membered heterocycles with two or more heteroatoms
-Six-membered heterocycles with one oxygen heteroatom (piranes, chromones, flavones and coumarins)
-Six membered heterocycles with one nitrogen atom (pyridine, quinoline, isoquinoline)
-Six membered heterocycles with two or more heteroatoms (purine, diazines etc.)
-Seven membered heterocyclic chemistry
- Heterocycles in supramolecular chemitry
-Heterocyclic compounds in organic snthesis
Participants
Dr. Kálai Tamás (BDF5M9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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174
OPF-MEM-T HEALTH BENEFITS OF HONEY AND OTHER BEE PRODUCTS
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 10 lectures + 14 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 3 – 15 Prerequisites: -
Topic
Honey and other products of the beehive (e.g. propolis, royal jelly) have had an important role in preserving our health since ancient
times. Today there is growing interest towards various fields of apitherapy both from healthcare professionals and people who intend to
use a bee product to alleviate the symptoms of a disease or for prevention. The course provides an overview about various fields of
apitherapy, including the origin, types, physico-chemical characteristics and medicinal application of honey, propolis, royal jelly and bee
venom - based on recent scientific evidence. The course will cover the issues related to the adulteration and identification of honey. The
practice will focus on the analysis of various types of honey: the botanical origin of honey will be confirmed with microscopical pollen
analysis and measurement of physico-chemical parameters, while the antioxidant and antimicrobial activity of honey will be determined
with in vitro tests.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Students have to pass 2 written tests with at least 60% of good answers.
Students are required to prepare lab notes based on laboratory activities.
Making up for missed classes
There is no possibility for making up for missed classes.
Reading material
- Obligatory literature
- Literature developed by the Department
Teaching materials (Power Point slideshows) will be available at the website of the Department of Pharmacognosy.
- Notes
- Recommended literature
The course will involve critical evaluation of recent literature sources (articles in scientific journals, book chapters, websites).
Lectures
1 Botanical and geographical origin of honeys.
Dr. Farkas Ágnes
2 Chemical composition of honey.
Dr. Farkas Ágnes
3 Honey types of Hungary (botanical origin, sensory analysis, physico-chemical properties).
Dr. Farkas Ágnes
4 Honey types worldwide (botanical origin, sensory analysis, physico-chemical properties).
Dr. Farkas Ágnes
5 Methods used in identification of honey samples. Honey adulteration.
Dr. Farkas Ágnes
6 Identifying honeys with microscopical pollen analysis.
Dr. Farkas Ágnes
7 Medicinal application of honey.
Dr. Farkas Ágnes
8 Antimicrobial effect of honey and propolis.
Dr. Farkas Ágnes
9 Other fields of apitherapy.
Dr. Farkas Ágnes
10 Other bee products with health benefits.
Dr. Farkas Ágnes
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Practices
1 Sensory analysis of honeys.
Dr. Farkas Ágnes
2 Examination of physico-chemical properties of honeys.
Dr. Farkas Ágnes
3 Microscopical pollen analysis of honeys I.
Dr. Farkas Ágnes
4 Microscopical pollen analysis of honeys II.
Dr. Farkas Ágnes
5 Microscopical pollen analysis of honeys III.
Dr. Farkas Ágnes
6 Microscopical pollen analysis of honeys IV.
Dr. Farkas Ágnes
7 Measuring antioxidant capacity of honey samples I.
Dr. Kocsis Marianna
8 Measuring antioxidant capacity of honey samples II.
Dr. Kocsis Marianna
9 Measuring antioxidant capacity of honey samples III.
Dr. Kocsis Marianna
10 Measuring antioxidant capacity of honey samples IV.
Dr. Kocsis Marianna
11 Determining the antimicrobial effect of honey samples with in vitro assays I.
Magné Balázs Viktória Lilla
12 Determining the antimicrobial effect of honey samples with in vitro assays II.
Magné Balázs Viktória Lilla
13 Determining the antimicrobial effect of propolis with in vitro assays I.
Magné Balázs Viktória Lilla
14 Determining the antimicrobial effect of propolis with in vitro assays II.
Magné Balázs Viktória Lilla
Seminars
Exam topics/questions
(1) Botanical and geographical origin of honey.
(2) Chemical composition of honey.
(3) Types of honeys in Hungary and abroad.
(4) Sensory analysis of honeys.
(5) Physico-chemical characteristics of different honey types.
(6) Methods for identifying various types of honey.
(7) Microscopic pollen analysis of honeys.
(8) Honey adulteration.
(9) Medicinal use of honey.
(10) Other fields of apitherapy.
(11) Other bee products with health benefits.
(12) Antioxidant activity of honeys.
(13) Antimicrobial effect of honey and propolis.
Participants
Dr. Farkas Ágnes (DKQUBQ), Dr. Kocsis Marianna (C9C3UN), Magné Balázs Viktória Lilla (B9FASU)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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176
OPF-TS1-T CALCULATIONS IN PHARMACEUTICAL TECHNOLOGY 1
Course director: DR. SZILÁRD PÁL, assistant professor
Institute of Pharmaceutical Technology and Biopharmacy [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OPG-C1E-T parallel + OPG-GI1-T completed
Topic
Aim of the course is to deepen the knowledge of calculations needed for Pharmaceutical Technology 1 practice (dose checking,
prescription reading and understanding) by solving and practicing several examples together with the course leader.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Participation on the seminars - accepted work reports - accepted written assessments Students have to write an end-semester assessment
from the lectures at acceptance level of 60%.
Making up for missed classes
Students must fulfill requirements determined by the Code of Studies and Examinations. Student has to make up the missed lectures and
do work reports.
Reading material
- Obligatory literature
- Literature developed by the Department
Seminar notes.
- Notes
- Recommended literature
European Pharmacopoeia
Formulae Normales VII. (FoNo VII.)
James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, New York, London
Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel
Chris Langley, Dawn Belcher: Pharmaceutical Compounding and Dispensing, Pharmaceutical Press
Attila Dévay: The Theory and Practice of Pharmaceutical Technology, electronic book, PTE-Pécs
Attila Dévay: Investigation of Pharmaceutical Preparations, electronic book, PTE-Pécs
Lectures
Practices
Seminars
1 Introduction to pharmaceutical technological calculations, praciticing and understanding expressions found on prescriptions
Dr. Pál Szilárd
2 Concept of concentration
Dr. Kása Péter
3 Basic calculations of clear solutions (mixing rule)
Dr. Ferenczi Krisztina
4 Calculations of ethanol dilution
Dr. Kása Péter
5 Fundamentals of dose checking (understanding the prescription, syrup factor, elderly factor)
Dr. Pál Szilárd
6 Dose checking in solutions 1.
Dr. Kása Péter
7 Dose checking in solutions 2.
Dr. Pál Szilárd
8 Dose checking in peroral drops 1.
Dr. Kása Péter
9 Dose checking in peroral drops 2.
Dr. Kása Péter
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10 Calculation of isotonicity 1.
Dr. Ferenczi Krisztina
11 Calculation of isotonicity 2.
Dr. Kása Péter
12 Test
Dr. Pál Szilárd
Exam topics/questions
Students can get the test topics in the institute or download the from website of the institute.
Participants
Dr. Ferenczi Krisztina (I8U2DJ), Dr. Kása Péter (ISWPRM), Dr. Pál Szilárd (FYF5E9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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178
OPF-VGG-T COLLECTING AND CONSERVATION OF WILD NATIVE MEDICINAL PLANTS
Course director: DR. DRAGICA PURGER, assistant professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 24 lectures + 4 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OPO-G2E-T completed + OPO-G2G-T completed
Topic
Collecting and conservation of wild native medicinal plants is an elective course that will help in obtaining wider knowledge related to
medicinal plants. The topic covers wild medicinal plants native to Hungary, their morphological description, their occurrence and
significance. It describes in detail the methodology and possibilities for collecting wild medicinal plants in nature, and discusses strategies
for the conservation of rare and endangered herb species. The course includes a half-day field trip to Pécs-Nagyarpád, where the main
focus is on the recognition of native wild medicinal plants in nature. The students can broaden their knowledge related to wild medicinal
plants and their application in pharmacist practice.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Written test
Making up for missed classes
Upon individual agreement. Field practices cannot be missed or made up for.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Shi Lin Chen et al. 2016: Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chin Med 11:37
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967523/pdf/13020_2016_Article_108.pdf)
Danna J. Leaman: Sustainable wild collection of medicinal and aromatic plants. Development of an international standard
https://library.wur.nl/frontis/medicinal_aromatic_plants/07_leaman.pdf
Medicinal Plant Specialist Group Species Survival Commission IUCN 2007: International Standard for Sustainable Wild Collection
of Medicinal and Aromatic Plants (ISSC-MAP) Version 1.0- The World Conservation Union
https://www.bfn.de/fileadmin/MDB/documents/service/skript195.pdf
Lectures
1 Importance of wild medicinal plants
Dr. Purger Dragica
2 Collection of wild medicinal plants in Hungary; historical overview
Dr. Purger Dragica
3 Methods of the collection of wild medicinal plants
Dr. Purger Dragica
4 Methods of the collection of wild medicinal plants
Dr. Purger Dragica
5 National and regional databases of wild medicinal plants
Dr. Purger Dragica
6 Collection Calendar
Dr. Purger Dragica
7 Primary processing of collected medicinal plants
Dr. Purger Dragica
8 Primary processing of collected medicinal plants
Dr. Purger Dragica
9 General quality requirements
Dr. Purger Dragica
10 General quality requirements
Dr. Purger Dragica
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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179
11 International conventions and rules
Dr. Purger Dragica
12 International conventions and rules
Dr. Purger Dragica
13 Estimating the population size of medicinal plants
Dr. Purger Dragica
14 Estimating the population size of medicinal plants
Dr. Purger Dragica
15 Endangered, protected and strictly protected native medicinal plants
Dr. Purger Dragica
16 Endangered, protected and strictly protected native medicinal plants
Dr. Purger Dragica
17 Monitoring populations of threatened species
Dr. Purger Dragica
18 Monitoring populations of threatened species
Dr. Purger Dragica
19 Strategies for conservation of endangered medicinal plants
Dr. Purger Dragica
20 Strategies for conservation of endangered medicinal plants
Dr. Purger Dragica
21 The role of botanical gardens in ex situ preserving of medicinal plants
Dr. Purger Dragica
22 The role of botanical gardens in ex situ preserving of medicinal plants
Dr. Purger Dragica
23 Exam: Written test
Dr. Purger Dragica
24 Exam: Written test
Dr. Purger Dragica
Practices
1 General information on plant parts collected
Dr. Purger Dragica
2 The most important wild native medicinal plants in Hungary, their habitats and distribution
Dr. Purger Dragica
3 Collecting wild medicinal plants in the field
Dr. Purger Dragica
4 Collecting wild medicinal plants in the field
Dr. Purger Dragica
Seminars
Exam topics/questions
1. Importance of wild medicinal plants
2. Collection of wild medicinal plants
3. Methods of the collection of wild medicinal plants
4. The most important wild native medicinal plants in Hungary
5. Collecting wild medicinal plants in the field
6. Collection Calendar
7. Primary processing of collected medicinal plants
8. General quality requirements
9. International conventions and rules
10. Estimating the population size of medicinal plants
11. Endangered, protected and strictly protected native medicinal plants
12. Monitoring populations of threatened species
13. Strategies for conservation of endangered medicinal plants
14. The role of botanical gardens in ex situ preserving of medicinal plants
Participants
Dr. Purger Dragica (FCCWBF)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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180
OPE-EFA-T ETHNOPHARMACOBOTANY
Course director: DR. NÓRA PAPP, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 5
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 4 – 20 Prerequisites: OPO-G1E-T completed + OPO-G2E-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
Several written sources are available on the ethnobotanical usage and pharmaceutical history of medicinal plants from the Ancient Times.
The course presents a summary about ethnobotanical data focusing on folk therapeutical methods and values of the Mediterranean area,
Transylvania, countries of Europe, Asia, America and Africa completed by the scientific activity and curriculum vitae of ethnobotanists
and researchers in this topic. Students receive a general approach about the rules and regularity of the special folk terminology, practice,
folk customs and symbols in consideration of medicinal plants. In addition to ethnobotanical methods, the actual state, position and
necessity of surveys are discussed during the course.
Conditions for acceptance of the semester
Satisfactory fulfilment of 2 written tests based on the lectures.
Absences: according to the Code of Studies and Examinations of the Medical School.
Mid-term exams
The required 2 tests can be retaken or corrected in the course.
Making up for missed classes
Lectures in Neptun / MS Teams.
Reading material
- Obligatory literature
- Literature developed by the Department
http://aok.pte.hu/en/egyseg/oktatasianyagok/1640
http://gytk.pte.hu/en/egyseg/oktatasianyagok/1640
Lectures in Neptun / MS Teams.
- Notes
- Recommended literature
Cunninham A. B.: Applied Ethnobotany. People, Wild Plant Use and Conservation, Earthscan, London, 2002
Ellen, Davi E., Hatfield, G.: Medicinal Plants in Folk Tradition an Ethnobotany of Britain and Ireland, Timber Press, Portland,
Cambridge, 2004
Lise Manniche: The Ancient Egyptian Herbal, The British Museum Press, London, 1989
Martin G. J.: Ethnobotany. A Methods Manual, Earthscan, London, 2007
Minnis P. E.: Ethnobotany. A Reader, University of Oklahoma Press, U.S.A., 2000
Moerman, Daniel E.: Native American Ethnobotany, Timber Press, Portland, London, 2010
Paye, Gabriell DeBear: Cultural Uses of Plants, The New York Botanical Garden Press, Bronx, New York, 2000
Lectures
1 Ethnopharmacological data of the Ancient Times (Egypt, Mesopotamia).
Dr. Papp Nóra
2 Ethnopharmacological data of the Ancient Times (Egypt, Mesopotamia).
Dr. Papp Nóra
3 Ethnobotanical studies of the Native Indian populations of North, South and Central America (Cuba, Mexico).
Dr. Papp Nóra
4 Ethnobotanical studies of the Native Indian populations of North, South and Central America (Cuba, Mexico).
Dr. Papp Nóra
5 Ethnopharmacology of the ancient cultures of Iran, China, India, Tibet, Japan.
Dr. Papp Nóra
6 Ethnopharmacology of the ancient cultures of Iran, China, India, Tibet, Japan.
Dr. Papp Nóra
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181
7 Ethnopharmacological values of the African countries
Dr. Papp Nóra
8 Ethnopharmacological values of the African countries
Dr. Papp Nóra
9 Ethnopharmacology of the Mediterranean region (Greece, Spain, Portugal, Italy).
Dr. Papp Nóra
10 Ethnopharmacology of the Mediterranean region (Greece, Spain, Portugal, Italy).
Dr. Papp Nóra
11 Ethnopharmacological data from the Middle Ages: therapy and medicinal plants in monastery gardens.
Dr. Papp Nóra
12 Ethnopharmacological data from the Middle Ages: therapy and medicinal plants in monastery gardens.
Dr. Papp Nóra
13 Transylvanian ethnobotanical values.
Dr. Papp Nóra
14 Transylvanian ethnobotanical values.
Dr. Papp Nóra
15 Ancient medico-botanical and herbal books and written sources with the morphological and therapeutical description of medicinal
plants.
Dr. Papp Nóra
16 Ancient medico-botanical and herbal books and written sources with the morphological and therapeutical description of medicinal
plants.
Dr. Papp Nóra
17 Scientific activity and curriculum vitae of ethnobotanists.
Dr. Papp Nóra
18 Scientific activity and curriculum vitae of ethnobotanists.
Dr. Papp Nóra
19 Written test I.
Dr. Papp Nóra
20 Written test I.
Dr. Papp Nóra
21 Interactive lecture: analysis and elaboration of scientific articles published in international journals and books based on the
knowledge and view of the previous lectures.
Dr. Papp Nóra
22 Interactive lecture: analysis and elaboration of scientific articles published in international journals and books based on the
knowledge and view of the previous lectures.
Dr. Papp Nóra
23 Methodologies in ethnobotanical collection.
Dr. Papp Nóra
24 Methodologies in ethnobotanical collection.
Dr. Papp Nóra
25 Documentation of ethnobotanical data - case studies
Dr. Papp Nóra
26 Documentation of ethnobotanical data - case studies
Dr. Papp Nóra
27 Written test II.
Dr. Papp Nóra
28 Written test II.
Dr. Papp Nóra
Practices
Seminars
Exam topics/questions
According to the topics of the course.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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182
OPE-FAO-T APPLIED HEALTH ECONOMICS
Course director: DR. ANTAL TAMÁS ZEMPLÉNYI, assistant professor
Department of Pharmaceutics and University Pharmacy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 5
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – 25 Prerequisites: OPG-GI1-T completed
Topic
Health economics applies economic thinking to the analysis of health and health care. This course provides students with an
understanding of the health economics principles and tools to analyse and address the challenges of limited resources faced by the health
sector.
By attending this course, students will
- earn about the key principles and methods of health economic evaluations and models
- know how to interpret the results of health economic evaluations
- gain insight into the perspective of decision makers
- better understand the crucial policy debates relating to health care.
The module is primarily aimed at medical, pharmacy and economic students who would like to improve their understanding of health
economics and research methods and at other students who are interested in the field.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Retake opportunity is possible following personal discussion.
Making up for missed classes
Retake opportunity is possible following personal discussion.
Reading material
- Obligatory literature
- Literature developed by the Department
All presentations can be downloaded from Neptun Meet Street.
- Notes
- Recommended literature
Lectures
1 Introduction to health economics, making decisions in healthcare 1.
Kovács Sándor
2 Introduction to health economics, making decisions in healthcare 2.
Kovács Sándor
3 Economic evaluation in healthcare (CEA, CUA, CBA), threshold 1.
Dr. Zemplényi Antal Tamás
4 Economic evaluation in healthcare (CEA, CUA, CBA), threshold 2.
Dr. Zemplényi Antal Tamás
5 Life tables and extrapolation 1.
Kovács Sándor
6 Life tables and extrapolation 2.
Kovács Sándor
7 Measuring and valuing health outcomes (QALY) and costs in healthcare 1.
Dr. Zemplényi Antal Tamás
8 Measuring and valuing health outcomes (QALY) and costs in healthcare 2.
Dr. Zemplényi Antal Tamás
9 Health technology assessment - case studies 1.
Dr. Zemplényi Antal Tamás
10 Health technology assessment - case studies 2.
Kovács Sándor
11 Introduction to modelling 1.
Dr. Zemplényi Antal Tamás
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183
12 Introduction to modelling 2.
Dr. Zemplényi Antal Tamás
13 Decision analytic modelling: decision trees (practical exercise) 1.
Dr. Zemplényi Antal Tamás
14 Decision analytic modelling: decision trees (practical exercise) 2.
Dr. Zemplényi Antal Tamás
15 Decision analytic modelling: Markov models (practical exercise) 1.
Dr. Zemplényi Antal Tamás
16 Decision analytic modelling: Markov models (practical exercise) 2.
Dr. Zemplényi Antal Tamás
17 Sensitivity analysis 1.
Kovács Sándor
18 Sensitivity analysis 2.
Kovács Sándor
19 Summary; presenting and interpreting cost-effectiveness analysis 1.
Dr. Zemplényi Antal Tamás
20 Summary; presenting and interpreting cost-effectiveness analysis 2.
Dr. Zemplényi Antal Tamás
21 Market access of new pharmaceuticals - case study 1.
Dr. Zemplényi Antal Tamás
22 Market access of new pharmaceuticals - case study 2.
Dr. Zemplényi Antal Tamás
23 Consultation 1.
Dr. Zemplényi Antal Tamás
24 Consultation 2.
Kovács Sándor
Practices
Seminars
Exam topics/questions
Based on the topics of the lectures.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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184
OPE-TG3-T STUDENT PROJECT RESEARCH FOR STUDENTS OF PHARMACEUTIST PROGRAMME 3
Course director: DR. GYÖRGYI HORVÁTH, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 5
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OPF-TG2-T completed
Topic
The course aims at promoting of students to make student research projects on the field of pharmaceutical sciences. Furthermore, we
wish to give individual possibilities of students to perform experiments in the different pharmaceutical institutes involved into Students
Research Society.
Conditions for acceptance of the semester
The continuous student’s work is recommended. The continuous enrollment of consecutive courses can be stopped and continued in
The prerequisite of this course (TDK 3): registration of the student in the database of Students’ Research Society and the fulfillment of
the Student Project Research for Students of Pharmaceutist Programme 2 course.
Mid-term exams
TG3
- Introduction of conference abstract or conference manuscript (student is co-author) for the course supervisor at the end of 13th week of
the semester.
- Introduction of original article published in national and/or international journals (student is co-author) at the end of 13th week of the
semester.
- Participation on Students’ Research Conference.
- Among the three conditions, one of them should be made at least.
Making up for missed classes
There is no possibility.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
ScienceDirect database
Lectures
Practices
Seminars
Exam topics/questions
Not applicable.
Participants
Dr. Horváth Györgyi (GDLTCH), Dr. Poór Miklós (ARWF5Z), Dr. Vida Róbert György (BN08GS)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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185
OPE-DM3-T DEMONSTRATOR ACTIVITY 3
Course director: DR. LÁSZLÓ JÓZSEF CZOPF, associate professor
1st Department of Internal Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 5
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OPE-DM2-T completed
Topic
This course gives support and acknowledgement for students performing documented and successful supervised teaching activities and
taking an active part in organizing courses.
The subjects can be taken up in eight semesters (in a total value of 16 credits).
Conditions for acceptance of the semester
Students have to register every semester as demonstrators, should provide proof of previous demonstrator activity, and the semester will
be signed on the basis of at least 24 hours of teaching or organizatory activity. The grades will be given according to the Code of
Demonstrators with additional requirements, that you can reach using the following links: Code of Demonstrator Students:
https://docs.google.com/document/d/1xkkyeRdZcDphnqWEkpON0SQf34MpBBJqogG09foI8Rw/edit?usp=sharing
Faculty Home Page of the Circle of Demonstrator Students (DDK):
http://aok.pte.hu/en/egyseg/almenu/980/339
Mid-term exams
At least two midsemester tests should be successfully completed to pass.
Making up for missed classes
There are no absences accepted from the 24 hours demonstrator activity.
Reading material
- Obligatory literature
- Literature developed by the Department
..
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
The topics of the tests depend on the specific course of the demonstrator activity.
Participants
Dr. Czopf László József (BAVD1M), Dr. Koppán Ágnes Judit (ZAEQDO), Dr. Sebők Judit (GLM10L), Dr. Tamás Andrea (F7QM8G),
Dr. Ujvári Balázs (EN1LY9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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186
OPF-DTS-T THE ROLE OF DRUG TRANSPORTERS
Course director: DR. LUCA JÁROMI, assistant professor
Department of Pharmaceutical Biotechnology [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ both semesters ▪ recommended semester: 6
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – 15 Prerequisites: OPG-R1E-T completed
Topic
Understanding the clinical importance, role and molecular procedures of interindividual variability in drug response is a critical area of
drug development and clinical pharmacotherapy.The genetic polymorphisms in drug-metabolizing enzymes, receptors, transporters and
other drug targets may have a crucial role in the background of this phenomenon, that can lead to the interindividual differences in
molecular ways, efficacy, as well as toxicity as a response to numerous clinical treatment. Cancer is the leading cause of mortality and
morbidity worldwide. The greatest obstacle of the successful treatment is the development of multidrug resistance (MDR) against
chemotherapy. During the past two decades, the act of carrier-mediated transport in defining the pharamcokinetics of drugs has become
progressively evident with the discovery of genetic polymorphisms that influence expression, localization, and/or function of a given
drug transporter. The aim of the course is to present the drug transporters and their genetic and pharmacogenetic background, to explain
their role in drug metabolism, especially focusing on different drug transporter families and on interactions of protein - drug - transporters.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Félév végén vizsga, vizsgaidőszakban pótvizsga lehetőségek
Making up for missed classes
Nincs, mert csak előadásokból áll a kurzus.
Reading material
- Obligatory literature
- Literature developed by the Department
PPT-bemutatók az előadások során.
- Notes
- Recommended literature
1.) Yuichi Sugiyama - Bente Steffansen: Transporters in Drug Development Discovery, Optimization,
Clinical Study and Regulation, ISSN 2210-7371 ISSN 2210-738X (electronic), ISBN 978-1-4614-8228-4 ISBN 978-1-4614-8229-1
(eBook), DOI 10.1007/978-1-4614-8229-1, Springer New York Heidelberg Dordrecht London
Library of Congress Control Number: 2013947789
2.) Toshihisa Ishikawa, Richard B. Kim: Pharmacogenomics of Human Drug Transporters, ISBN 978-0-470-92794-6
3.) Russ. B. Altman, David Flockhart, David B. Goldstein: Pharmacogenetics and Pharmacogenomics, ISBN 978-0-521-88537-9
Lectures
1 Introduction to world of drug transporters
Dr. Járomi Luca
2 General characteristics of drug transporters
Dr. Járomi Luca
3 Terms definition of drug transporters
Dr. Járomi Luca
4 Genetic role of drug transporters
Dr. Járomi Luca
5 Pharmacogenetic characteristics of drug transporters
Dr. Járomi Luca
6 Basics in phamacokinetics: definition of absorption, distribution, metabolism, and excretion (ADME)
Dr. Járomi Luca
7 Explanation of absorption, distribution, metabolism, and excretion (ADME)
Dr. Járomi Luca
8 Membrane transporters in ADME I.
Dr. Járomi Luca
9 Membrane transporters in ADME II.
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187
Dr. Járomi Luca
10 ADME pharmacogenomics in drug development I.
Dr. Járomi Luca
11 ADME pharmacogenomics in drug development II.
Dr. Járomi Luca
12 The role of transporters in drug development: regulatory science perspectives from the FDA
Dr. Járomi Luca
13 Industrial evaluation of drug transporters in ADME
Dr. Járomi Luca
14 The pharmacogenomics of membrane transporters I.
Dr. Járomi Luca
15 The pharmacogenomics of membrane transporters II.
Dr. Járomi Luca
16 Nucleoside transporters family
Dr. Járomi Luca
17 General characteristics of ABC-transporter family
Dr. Járomi Luca
18 Most relevant ones: ABC-transporters
Dr. Járomi Luca
19 P-glycoprotein (MDR1/ABCB1)
Dr. Járomi Luca
20 ABCG2
Dr. Járomi Luca
21 Cancer: exsorptive transporters (ABC) expressed on transformed cells
Dr. Járomi Luca
22 Proton-coupled nutrient transporters affect ADME properties
Dr. Járomi Luca
23 In vitro characterization of interactions with drug transporting proteins
Dr. Járomi Luca
24 In vivo characterization of interactions on transporters
Dr. Járomi Luca
25 Indication specific transporter studies
Dr. Járomi Luca
26 Future perspectives
Dr. Járomi Luca
27 Conclusions and outlook, summary
Dr. Járomi Luca
28 Exam
Dr. Járomi Luca
Practices
Seminars
Exam topics/questions
Introduction to world of drug transporters
General characteristics of drug transporters
Terms definition of drug transporters
Genetic role of drug transporters
Pharmacogenetic characteristics of drug transporters
Basics in phamacokinetics: definition of absorption, distribution, metabolism, and excretion (ADME)
Explanation of absorption, distribution, metabolism, and excretion (ADME)
Membrane transporters in ADME I.
Membrane transporters in ADME II.
ADME pharmacogenomics in drug development I.
ADME pharmacogenomics in drug development II.
The role of transporters in drug development: regulatory science perspectives from the FDA
Industrial evaluation of drug transporters in ADME
The pharmacogenomics of membrane transporters I.
The pharmacogenomics of membrane transporters II.
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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188
Nucleoside transporters family
General characteristics of ABC-transporter family
Most relevant ones: ABC-transporters
P-glycoprotein (MDR1/ABCB1)
ABCG2
Cancer: exsorptive transporters (ABC) expressed on transformed cells
Proton-coupled nutrient transporters affect ADME properties
In vitro characterization of interactions with drug transporting proteins
In vivo characterization of interactions on transporters
Indication specific transporter studies
Future perspectives
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
189
OPF-NSG-T PLANT PRODUCTS IN THE PHARMACEUTICAL PRACTICE
Course director: DR. GYÖRGYI HORVÁTH, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 6
Number of hours/semester: 20 lectures + 8 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – 15
Prerequisites: OPO-G1E-T completed + OPO-G2E-T completed + OPG-O1E-T completed
Topic
Students will be familiar with the results of the latest studies on medicinal plants used in the prevention and treatment of diseases, and
the availability of authorized preparations and their use in modern medicine and health care, with their pharmacobotanical and
pharmacognosic knowledge. They should be able to make herbal preparations based on their knowledge.
Task: To present the active ingredient, medicinal use of medicinal herbs and preparations used in healing, to present the latest results of
phytotherapy research. Preparing tea blends and externally usable preparations in the practice sessions.
Requirement: Students should be able to apply their acquired knowledge to the highest possible level in their profession.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
During the semester, writing of one test at an acceptable level (min. 60%) is mandatory. In case of failed result, one possibility to repeat
is possible. Taking one student lecture is mandatory.
Making up for missed classes
No replacement is possible.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
1. Aronson, JK.: Meyler’s Side Effects of Herbal Medicines, Elsevier, Oxford 2009
2. ESCOP Monographs, 2nd edition, Thieme, United Kingdom 2003
Lectures
1 Introduction. Plants on the market and their role in today’s medicine and pharmacy.
Dr. Horváth Györgyi
2 Availability of medicinal plant products on the Internet: dangers, challenges.
Dr. Horváth Györgyi
3 Herbs and products acting on the central nervous system.
Dr. Horváth Györgyi
4 Herbs and products acting on the central nervous system.
Dr. Horváth Györgyi
5 Herbs and products acting on heart and vascular system.
Dr. Horváth Györgyi
6 Herbs and products acting on heart and vascular system.
Dr. Horváth Györgyi
7 Herbs and products acting on respiratory tract.
Dr. Horváth Györgyi
8 Herbs and products acting on respiratory system.
Dr. Horváth Györgyi
9 Herbs and products acting on gastrointestinal tract.
Dr. Horváth Györgyi
10 Herbs and products acting on gastrointestinal tract.
Dr. Horváth Györgyi
11 Herbs and products acting on urinary tract.
Dr. Horváth Györgyi
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190
12 Herbs and products acting on urinary tract.
Dr. Horváth Györgyi
13 Herbal remedies for gynecological complaints.
Dr. Horváth Györgyi
14 Adaptogens.
Dr. Horváth Györgyi
15 Herbal remedies for dermatological diseases.
Dr. Horváth Györgyi
16 Herbal remedies for dermatological diseases.
Dr. Horváth Györgyi
17 Herbs and remedies for treating pain.
Dr. Horváth Györgyi
18 Herbs and products for treating pain.
Dr. Horváth Györgyi
19 Enhancing the body’s resistance (plant immunomodulators).
Dr. Horváth Györgyi
20 Students’s lecture. Written test.
Dr. Horváth Györgyi
Practices
1 Location of herbal remedies in today’s pharmaceuticals I: Preparation of herbal product.
Dr. Horváth Györgyi
2 Location of herbal remedies in today’s pharmaceuticals I: Preparation of herbal product.
Dr. Horváth Györgyi
3 Location of herbal remedies in today’s pharmaceuticals II: Evaluation of herbal product.
Dr. Horváth Györgyi
4 Location of herbal remedies in today’s pharmaceuticals II: Evaluation of herbal product.
Dr. Horváth Györgyi
5 Praparation of herbal tea.
Dr. Horváth Györgyi
6 Macroscopic and organoleptic examination of herbal tea preparation.
Dr. Horváth Györgyi
7 Preparation of product containing essential oils.
Dr. Horváth Györgyi
8 Checking the quality of herbal substances by chromatography: TLC.
Dr. Horváth Györgyi
Seminars
Exam topics/questions
The topics of the written test is the same with the lectures.
Participants
Dr. Horváth Györgyi (GDLTCH)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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191
OPF-TS2-T CALCULATIONS IN PHARMACEUTICAL TECHNOLOGY 2
Course director: DR. SZILÁRD PÁL, assistant professor
Institute of Pharmaceutical Technology and Biopharmacy [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 6
Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OPG-C2E-T parallel + OPG-C1E-T completed
Topic
Aim of the course is to deepen the knowledge of calculations needed for Pharmaceutical Technology 2 practice (dose checking,
prescription reading and understanding) by solving and practicing several examples together with the course leader.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Participation on the seminars - accepted work reports - accepted written assessments Students have to write an end-semester assessment
from the lectures at acceptance level of 60%.
Making up for missed classes
Students must fulfil requirements determined by the Code of Studies and Examinations. Student has to make up the missed lectures and
do work reports.
Reading material
- Obligatory literature
- Literature developed by the Department
Seminar notes.
- Notes
- Recommended literature
European Pharmacopoeia
Formulae Normales VII. (FoNo VII.)
James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, New York, London
Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel
Chris Langley, Dawn Belcher: Pharmaceutical Compounding and Dispensing, Pharmaceutical Press
Attila Dévay: The Theory and Practice of Pharmaceutical Technology, electronic book, PTE-Pécs
Attila Dévay: Investigation of Pharmaceutical Preparations, electronic book, PTE-Pécs
Lectures
Practices
Seminars
1 Introduction to calculations of disperse systems
Dr. Kása Péter
2 Calculations related to HLB value
Dr. Kása Péter
3 Dose checking in emulsions
Dr. Kása Péter
4 Dose checking in suspensions
Dr. Kása Péter
5 Calculations related to semi-solid dosage forms
Dr. Kása Péter
6 Introduction to calculations related to suppositories (calibration value and displacement factor)
Dr. Kása Péter
7 Calculations of divided form of prescribing suppositories
Dr. Kása Péter
8 Calculations of dispensed form of prescribing suppositories
Dr. Kása Péter
9 Dose checking of suppositories 1.
Dr. Kása Péter
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10 Dose checking of suppositories 2.
Dr. Kása Péter
11 Dose checking of divided and undivided powders
Dr. Kása Péter
12 Test
Dr. Pál Szilárd
Exam topics/questions
Students can get the test topics in the institute or download the from website of the institute.
Participants
Dr. Kása Péter (ISWPRM), Dr. Pál Szilárd (FYF5E9)
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193
OPE-STK-T BASICS OF STEREOCHEMISTRY
Course director: DR. ZSUZSANNA ROZMER, assistant professor
Department of Pharmaceutical Chemistry [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ spring semester ▪ recommended semester: 6
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 5 – 15
Prerequisites: OPA-S2E-T completed + OPG-R1E-T completed + OPO-GE2-T completed
Topic
In the frame of this topic we will provide an overview about fundamentals of stereochemical definitions and processes. The students will
receive the most important knowledge about stereochemistry, with what they can understand the different binding types of drugs to their
place of biological action.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Students will have to write a written test at the end of the semester.
Making up for missed classes
In case of absences the students must follow up with self-education!
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture notes provided by the lecturer.
- Notes
Lecture notes provided by the lecturer.
- Recommended literature
K.-H. Hellwich, C. D. Siebert: Stereochemistry workbook, 191 problems and solutions, Springer, 2006.
Lectures
1 Introduction, confoguration, conformation definitions.
Dr. Huber Imre
2 Chirality, asymmetry.
Dr. Huber Imre
3 Asymmetric syntheses
Dr. Huber Imre
4 Fischer projection, CIP system.
Dr. Huber Imre
5 Diastereomers, enantiomers.
Dr. Huber Imre
6 Epimers, eutomers, distomers.
Dr. Huber Imre
7 Homochirality, inversion, meso-isomers.
Dr. Huber Imre
8 Newman projection.
Dr. Huber Imre
9 Optical purity.
Dr. Huber Imre
10 Prochirality, prostereoisomerism.
Dr. Huber Imre
11 Racemate, racemisation.
Dr. Huber Imre
12 Retention in stereochemistry.
Dr. Huber Imre
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194
13 Stereoselectivity, stereospecificity.
Dr. Huber Imre
14 Summary, written test.
Dr. Huber Imre
Practices
Seminars
Exam topics/questions
These are listed in the lecture notebook written by the lecturer. These notes are about the different questions of this field with the
corresponding answers, parallely.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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195
OPE-GFK-T PHYSICO-CHEMICAL BASES OF DRUG ACTION
Course director: DR. ZSUZSANNA ROZMER, assistant professor
Department of Pharmaceutical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 6
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 15 Prerequisites: -
Topic
The main objective of this course is to expand the knowledge in phyisico-chemical characterization of drug molecules and drug targets
for better understanding the drug action.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Written test.
Making up for missed classes
None.
Reading material
- Obligatory literature
- Literature developed by the Department
Zsuzsanna Rozmer, Pál Perjési: The physico-chemeical bases of drug actions. PTE, 2015.
- Notes
- Recommended literature
Lectures
1 Molecular bases of biological actions. Structural characteristics of drug targets.
Dr. Rozmer Zsuzsanna
2 Molecular bases of biological actions. Structural characteristics of drug targets.
Dr. Rozmer Zsuzsanna
3 Receptors as drug targets.
Dr. Rozmer Zsuzsanna
4 Receptors as drug targets.
Dr. Rozmer Zsuzsanna
5 Enzymes as drug targets.
Dr. Rozmer Zsuzsanna
6 Enzymes as drug targets.
Dr. Rozmer Zsuzsanna
7 Transporters and ion channels as drug targets.
Dr. Rozmer Zsuzsanna
8 Transporters and ion channels as drug targets.
Dr. Rozmer Zsuzsanna
9 Nucleic acids as drug targets.
Dr. Rozmer Zsuzsanna
10 Nucleic acids as drug targets.
Dr. Rozmer Zsuzsanna
11 Physicochemical properties of drug-drug target interactions. Intermolecular bonding.
Dr. Rozmer Zsuzsanna
12 Physicochemical properties of drug-drug target interactions. Intermolecular bonding.
Dr. Rozmer Zsuzsanna
13 Physicochemical properties of drug-drug target interactions. Affinity. Efficiency and selectivity.
Dr. Rozmer Zsuzsanna
14 Physicochemical properties of drug-drug target interactions. Affinity. Efficiency and selectivity.
Dr. Rozmer Zsuzsanna
15 Physicochemical properties of drug-drug target interactions. Stucture, stereochemistry.
Dr. Rozmer Zsuzsanna
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196
16 Physicochemical properties of drug-drug target interactions. Stucture, stereochemistry.
Dr. Rozmer Zsuzsanna
17 Physicochemical characteristics of drugs. Solubility.
Dr. Rozmer Zsuzsanna
18 Physicochemical characteristics of drugs. Solubility.
Dr. Rozmer Zsuzsanna
19 Physicochemical characteristics of drugs. Acid-base properties. Relevance and determination of the pKa value.
Dr. Rozmer Zsuzsanna
20 Physicochemical characteristics of drugs. Acid-base properties. Relevance and determination of the pKa value.
Dr. Rozmer Zsuzsanna
21 Physicochemical characteristics of drugs. Lipophilicity and partition coefficient. Determination of partition coefficients.
Dr. Rozmer Zsuzsanna
22 Physicochemical characteristics of drugs. Lipophilicity and partition coefficient. Determination of partition coefficients.
Dr. Rozmer Zsuzsanna
23 Physicochemical characteristics of drugs. Permeability. Experimental methods to determine permeability.
Dr. Rozmer Zsuzsanna
24 Physicochemical characteristics of drugs. Permeability. Experimental methods to determine permeability.
Dr. Rozmer Zsuzsanna
25 In silico ADME modelling. In vitro and in vivo tests.
Dr. Rozmer Zsuzsanna
26 In silico ADME modelling. In vitro and in vivo tests.
Dr. Rozmer Zsuzsanna
27 Physicochemical characteristics of drugs. Metabolic stability.
Dr. Rozmer Zsuzsanna
28 Physicochemical characteristics of drugs. Metabolic stability.
Dr. Rozmer Zsuzsanna
Practices
Seminars
Exam topics/questions
Topics of the written tests are set by the course director.
Participants
Dr. Rozmer Zsuzsanna (IIDYH7)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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197
OPE-TG4-T STUDENT PROJECT RESEARCH FOR STUDENTS OF PHARMACEUTIST PROGRAMME 4
Course director: DR. GYÖRGYI HORVÁTH, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 6
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OPE-TG3-T completed
Topic
The course aims at promoting of students to make student research projects on the field of pharmaceutical sciences. Furthermore, we
wish to give individual possibilities of students to perform experiments in the different pharmaceutical institutes involved into Students
Research Society.
Conditions for acceptance of the semester
The continuous student’s work is recommended. The continuous enrollment of consecutive courses can be stopped and continued in
The prerequisite of this course (TDK 4): registration of the student in the database of Students’ Research Society and the fulfillment of
the Student Project Research for Students of Pharmaceutist Programme 3 course.
Mid-term exams
TG4
- Introduction of conference abstract or conference manuscript (student is co-author) for the course supervisor at the end of 13th week of
the semester.
- Introduction of an article published in a national and/or international journal (student is co-author). It must be sent to the course
supervisor at the end of 13th week of the semester.
- Oral presentation at the Students’ Research Conference.
- Dean’s thesis
- Among the four conditions, one of them should be made at least.
Making up for missed classes
There is no possibility.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
ScienceDirect database
Lectures
Practices
Seminars
Exam topics/questions
Not applicable.
Participants
Dr. Horváth Györgyi (GDLTCH), Dr. Poór Miklós (ARWF5Z), Dr. Vida Róbert György (BN08GS)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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198
OPE-VFM-T BUSINESS DEVELOPMENT AND MANAGEMENT
Course director: DR. RITA BOGNÁR, research associate professor
Department of Biochemistry and Medical Chemistry [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 6
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 24 Prerequisites: -
Topic
The main objective of the course is to develop the business orientation skills of the students, while deepening their knowledge in business
models, business plans, innovative business strategies, time-, product-, process- and human resource management. Participants will have
the capability how to develop healthcare businesses in international environment and how to plan better their time.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
TVSZ szerint
Making up for missed classes
TVSZ szerint
Reading material
- Obligatory literature
- Literature developed by the Department
Neptun
- Notes
- Recommended literature
1. Baum Neil, Thomas Raju : The Basics of Business of Medicine, 2015
2. Helen Ewing: Healthcare Finance: An Introduction to Accounting and Financial Management, 5th edition, 2013
Lectures
1 Global healthcare
Dr. Bognár Rita
2 Different healthcare systems
Dr. Bognár Rita
3 Regional healthcare
Dr. Bognár Rita
4 Different types of business organisations
Dr. Bognár Rita
5 Innovation, Innovative businesses
Dr. Bognár Rita
6 Business Model Generation
Dr. Bognár Rita
7 Business plan
Dr. Bognár Rita
8 Business plan development
Dr. Bognár Rita
9 Intercultural business communication
Dr. Bognár Rita
10 Basics of Marketing in healthcare business
Dr. Bognár Rita
11 Production
Dr. Bognár Rita
12 Product and process management
Dr. Bognár Rita
13 Quality management
Dr. Bognár Rita
14 Time planning, Time management
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199
Dr. Bognár Rita
15 Human resource management
Dr. Bognár Rita
16 Team building, Team work
Dr. Bognár Rita
17 Strategic management
Dr. Bognár Rita
18 Risk management
Dr. Bognár Rita
19 Healthcare finance
Dr. Bognár Rita
20 Introduction to accounting and financial management
Dr. Bognár Rita
21 Sustainable healthcare
Dr. Bognár Rita
22 Presenation methods and techniques
Dr. Bognár Rita
23 Administration, Documentation, Reports
Dr. Bognár Rita
24 Summary
Dr. Bognár Rita
Practices
Seminars
Exam topics/questions
Neptun
Participants
Dr. Bognár Rita (HEILL4)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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200
OPE-ASZ-T THE ANTIMICROBIAL DRUGS AND THEIR CLINICAL USE
Course director: DR. BÉLA KOCSIS, associate professor
Department of Medical Microbiology and Immunology [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 6
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 5 – 100 Prerequisites: -
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
The aim of these lectures is to give a reliable and detailed knowledge about the antimicrobial drugs and their clinical use; to give ideas
how to choose the proper drug for the prophylaxis and therapy of infectious diseases
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
In the first 2 weeks of the exam period we give three times possibilities to write tests
Making up for missed classes
None
Reading material
- Obligatory literature
Jawetz et al.: Medical Microbiology
- Literature developed by the Department
- Notes
- Recommended literature
Lectures
1 Introduction, historical data, basic definitions
Dr. Kocsis Béla
2 Characterisation of antimicrobial drugs, chemical structure, their targets
Dr. Kocsis Béla
3 Characterisation of antimicrobial drugs, sensitivity and resistance
Dr. Kocsis Béla
4 Pharmacokinetics and pharmacodynamics of anti-infective drugs
Dr. Kocsis Béla
5 The antibiotic prophylaxis.
Dr. Kocsis Béla
6 The empiric antimicrobial therapy
Dr. Kocsis Béla
7 The antimicrobial therapy based on microbiologic result
Dr. Kocsis Béla
8 The choice of best antimicrobial drug
Dr. Kocsis Béla
9 The reasons of an unsuccessful antimicrobial therapy
Dr. Kocsis Béla
10 The antimicrobial drugs in details. The inhibitors of the cell wall biosynthesis Beta-lactams Penicillins
Dr. Kocsis Béla
11 Cephalosporins, carbapenems, monobactams, glicopeptides
Dr. Kocsis Béla
12 The inhibitors of the protein biosynthesis Aminoglicosides
Dr. Kocsis Béla
13 Tetracyclines Chloramphenicol Macrolides
Dr. Kocsis Béla
14 The inhibitors of the nucleic acid biosynthesis Rifampins Sulfonamides
Dr. Kocsis Béla
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201
15 Kinolons Fluorokinolons
Dr. Kocsis Béla
16 The antimycotic drugs
Dr. Kocsis Béla
17 The antiviral drugs HIV - AIDS
Dr. Kocsis Béla
18 The antiparasitic therapy. The chemoprophylaxis of malaria
Dr. Kocsis Béla
19 The antimicrobial therapy of respiratory and urinary tract infections
Dr. Kocsis Béla
20 Cardiovascular and wound infections, sepsis
Dr. Kocsis Béla
21 Central nervous system, abdominal and enteric infections
Dr. Kocsis Béla
22 Antimicrobial therapy of patients under immunosuppression, pregnancy....
Dr. Kocsis Béla
23 The pharmacological aspects of antimicrobial therapy
Dr. Kocsis Béla
24 The future of antimicrobial therapy
Dr. Kocsis Béla
Practices
Seminars
Exam topics/questions
None
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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202
OPE-DM4-T DEMONSTRATOR ACTIVITY 4
Course director: DR. LÁSZLÓ JÓZSEF CZOPF, associate professor
1st Department of Internal Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 6
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OPE-DM3-T completed
Topic
This course gives support and acknowledgement for students performing documented and successful supervised teaching activities and
taking an active part in organizing courses.
The subjects can be taken up in eight semesters (in a total value of 16 credits).
Conditions for acceptance of the semester
Students have to register every semester as demonstrators, should provide proof of previous demonstrator activity, and the semester will
be signed on the basis of at least 24 hours of teaching or organizatory activity. The grades will be given according to the Code of
Demonstrators with additional requirements, that you can reach using the following links: Code of Demonstrator Students:
https://docs.google.com/document/d/1xkkyeRdZcDphnqWEkpON0SQf34MpBBJqogG09foI8Rw/edit?usp=sharing
Faculty Home Page of the Circle of Demonstrator Students (DDK):
http://aok.pte.hu/en/egyseg/almenu/980/339
Mid-term exams
At least two midsemester tests should be successfully completed to pass.
Making up for missed classes
There are no absences accepted from the 24 hours demonstrator activity.
Reading material
- Obligatory literature
- Literature developed by the Department
..
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
The topics of the tests depend on the specific course of the demonstrator activity.
Participants
Dr. Czopf László József (BAVD1M), Dr. Koppán Ágnes Judit (ZAEQDO), Dr. Sebők Judit (GLM10L), Dr. Tamás Andrea (F7QM8G),
Dr. Ujvári Balázs (EN1LY9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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203
OPE-KPR-T CHEMOPREVENTION
Course director: DR. TÍMEA VARJAS, assistant professor
Department of Public Health Medicine [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 6
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 20 Prerequisites: OPO-G2B-T completed
Topic
Chemoprevention is the administration of natural or (semi)synthetic agents to prevent, inhibit, or delay the progression of chronic
diseases. The focus is on cancer chemoprevention.
The way from a potent agent to a chemopreventive strategy will also be discussed.
Involving (chemo)preventive interventions in every-day practice could spare valuable life years.
Conditions for acceptance of the semester
Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied.
Examination: test
Mid-term exams
Examination: test
Making up for missed classes
based on individual consideration
Reading material
- Obligatory literature
- Literature developed by the Department
PPT-presentations (Neptun)
- Notes
- Recommended literature
Lectures
1 Introduction - Chemoprevention as a preventive strategy
Dr. Szabó István
2 Introduction - Chemoprevention as a preventive strategy
Dr. Szabó István
3 Finding evidence
Dr. Szabó István
4 Finding evidence
Dr. Szabó István
5 Interventing chronic diseases
Dr. Szabó István
6 Interventing chronic diseases
Dr. Szabó István
7 Chemopreventive strategies - antioxidants
Dr. Szabó István
8 Actualities of antioxidants
Dr. Szabó István
9 Natural chemopreventive agents
Dr. Szabó István
10 Natural chemopreventive agents
Dr. Szabó István
11 Chemopreventive dietary factors
Dr. Szabó István
12 Chemopreventive dietary factors
Dr. Szabó István
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Practices
Seminars
Exam topics/questions
Neptun
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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205
OPF-FEA-T BASICS OF INFECTIOUS DISEASE EPIDEMIOLOGY
Course director: DR. ISTVÁN ZOLTÁN KISS, professor
Department of Public Health Medicine [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester: 9 lectures + 3 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 15 Prerequisites: OPO-I2E-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
However the morbidity and mortality caused by infectious diseases has significantly declined in the developed countries in the last
century due to the effective prevention methods, their complete elimination is not possible, infectious diseases are still part of our
everyday life. The spread of infectious diseases could be controlled by timely identification, proper investigation and by targeted
interventions. Aim of the course is to present the special characteristics of infectious diseases, and of infectious disease epidemiology;
basics and functioning of surveillance systems, the basics and steps of an outbreak investigation, and epidemiological methods used
during the investigation.
Conditions for acceptance of the semester
The participation in the lectures, seminars, practises is obligatory (a catalogue should be signed), a maximum of 2x45 min absence is
acceptable, above the signature will be rejected.
Mid-term exams
Making up for missed classes
None
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Heymann (ed.): Control of Communicable Diseases Manual
Mikanatha, Lynfield, Van Beneden, de Valk (eds.): Infectious Disease Surveillance
Lectures
1 Special characteristics of infectious diseases
Dr. Prantner Ida
2 Basics of infectious disease epidemiology I
Dr. Prantner Ida
3 Basics of infectious disease epidemiology II
Dr. Prantner Ida
4 Methods used in infectious disease epidemiology
Dr. Prantner Ida
5 Basic principles of surveillance
Dr. Prantner Ida
6 Infectious disease surveillance
Dr. Prantner Ida
7 Basics and steps of outbreak investigation I
Dr. Prantner Ida
8 Basics and steps of outbreak investigation II
Dr. Prantner Ida
9 Investigation of a food-borne outbreak
Dr. Prantner Ida
Practices
1 Use of epidemiological knowledge in practice I (definitions, surveillance data interpretation, analysis)
Dr. Prantner Ida
2 Use of epidemiological knowledge in practice II (Data collection, analysis, graphical interpretations)
Dr. Prantner Ida
3 Use of epidemiological knowledge in practice III (analytic studies)
Dr. Prantner Ida
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Seminars
Exam topics/questions
Participants
Dr. Prantner Ida (WO4A8D)
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207
OPF-KIA-T ESSENTIAL OILS AND CLINICAL AROMATHERAPY
Course director: DR. GYÖRGYI HORVÁTH, associate professor
Department of Pharmacognosy [email protected]
2 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 50 Prerequisites: OPG-O1E-T completed + OPG-O2E-T completed
Topic
Essential oils (EOs) are very interesting natural products and among other qualities they possess various biological properties. The term
biological comprises to all activities that these mixtures of volatile compounds (mainly mono- and sesquiterpenoids, phenylpropanoids,
etc.) exert on humans. EOs are used for their therapeutic action, for flavouring, in perfumery, or as starting materials for the synthesis of
other compounds. For therapeutic purposes they are administered as inhalations (e.g. eucalyptus oil), orally (e.g. peppermint oil) and
transdermally (e.g. rosmary oil). Oils with a high phenol content, for instance thyme and clove, have antiseptic properties, whereas others
are used as carrminatives. Oils showing antispasmodic activity, and much used in popular medicine, are those of melissa, peppermint,
chamomile, fennel, caraway and orange. Furthermore, in traditional medicine, EOs are also well-known for their analeptic, antimicrobial,
antinociceptive, antiphlogistic, antioxidative and sedative activities. All terpenoids easily enter the human body by oral absorption,
penetration through the skin, or inhalation very often leading to measurable blood concentrations. The aim of this course is to introduce
the most important medicinal plants containing essential oils and their medicinal role in the therapy and the clinical aromatherapy. We
would like to highlight their appropriate use, their profiles, but to call students’ attention to the cautions and contraindications of EOs, as
well.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Two written exams during the semester, acceptance of them from 60%.
Making up for missed classes
There is no possibility.
Reading material
- Obligatory literature
- Literature developed by the Department
PowerPoint presentations prepared by lecturers.
- Notes
- Recommended literature
1. Evans W.C.: Trease and Evans Pharmacognosy, Saunders, London, New York, 2000
2. Tisserand R., Balacs T.: Essential Oil Safety: A Guide for Health Care Professionals, Churchill Livingstone, 1995
3. Tisserand R., Young R: Essential Oil Safety: A Guide for Health Care Professionals, Second edition, Churchill Livingstone, 2013
Baser C.H, Buchbauer G.: Handbook of Essential Oils. Science, Technology and Application. CRC Press, Boca Raton, 2010
Lectures
1 Introduction of the course requirements. Definition of aromatherapy and clinical aromatherapy.
Dr. Horváth Györgyi
2 Advantages and disadvantages of the application of essential oils.
Dr. Horváth Györgyi
3 History of the use of essential oils.
Dr. Horváth Györgyi
4 Biological activities of essential oils.
Dr. Horváth Györgyi
5 Sources of essential oils.
Dr. Horváth Györgyi
6 Chemistry of essential oils. Chemical composition of essential oils.
Dr. Horváth Györgyi
7 Extraction techniques of essential oils: water-steam distillation, enfleurage, expression, supercritical fluid extraction. Gas
chromatographic analysis of essential oils.
Dr. Horváth Györgyi
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8 Extraction techniques of essential oils: water-steam distillation, enfleurage, expression, supercritical fluid extraction. Gas
chromatographic analysis of essential oils.
Dr. Horváth Györgyi
9 Drugs containing essential oils in the European Pharmacopoeia and in the ESCOP Monograph.
Dr. Horváth Györgyi
10 Quality of essential oils according to the official Pharmacopoeias.
Dr. Horváth Györgyi
11 External application of essential oils.
Dr. Horváth Györgyi
12 The most important base oils.
Dr. Horváth Györgyi
13 Physiological effects of essential oils. Metabolism of essential oil components in animal models and humans.
Dr. Horváth Györgyi
14 Contraindications.
Dr. Horváth Györgyi
15 Written test I
Dr. Horváth Györgyi
16 Written test I
Dr. Horváth Györgyi
17 Antimicrobial activity of essential oils. In vitro methods.
Dr. Horváth Györgyi
18 Antimicrobial activity of essential oils. In vivo methods.
Dr. Horváth Györgyi
19 Description of essential oils I: their main components and medicinal use. Peppermint oil, lemon oil, citronella oil, pine oil,
lavender oil.
Dr. Horváth Györgyi
20 Description of essential oils I: their main components and medicinal use. Peppermint oil, lemon oil, citronella oil, pine oil,
lavender oil.
Dr. Horváth Györgyi
21 Description of essential oils II: their main components and medicinal use. Clary sage oil, rosemary oil, tea tree oil, clove oil,
thyme oil, chamomile oil.
Dr. Horváth Györgyi
22 Description of essential oils II: their main components and medicinal use. Clary sage oil, rosemary oil, tea tree oil, clove oil,
thyme oil, chamomile oil.
Dr. Horváth Györgyi
23 Description of essential oils II.: their main components and medicinal use. Cinnamon oil, bitter and sweet orange oil, anise oil,
carraway oil, eucalyptus oil, sweet fennel oil, spearmint oil.
Dr. Horváth Györgyi
24 Description of essential oils II.: their main components and medicinal use. Cinnamon oil, bitter and sweet orange oil, anise oil,
carraway oil, eucalyptus oil, sweet fennel oil, spearmint oil.
Dr. Horváth Györgyi
25 Safety guidelines of essential oils.
Dr. Horváth Györgyi
26 Safety guidelines of essential oils.
Dr. Horváth Györgyi
27 Written test II
Dr. Horváth Györgyi
28 Written test II
Dr. Horváth Györgyi
Practices
Seminars
Exam topics/questions
There is no list. The questions of the written test is similar to the lecture topics.
Participants
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209
OPE-FMA-T DATA ANALYSIS 1
Course director: DR. LÁSZLÓ PÓTÓ, associate professor
Institute of Bioanalysis [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ both semesters ▪ recommended semester: 7
Number of hours/semester: 6 lectures + 6 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 12 Prerequisites: -
Topic
The goal of this course is to help students to prepare for thesis writing or making their own student research project. It covers mainly two
fields of that: read and interpret scientific papers and prepare an own study plan. Shortly to say: How to prepare for your own study
project.
Block One: The medical papers are likely the most important source to improve your present knowledge as a student and as an
MD. Most of these ‘original papers’ are based on carefully planned data collection and evaluation applying a wide array of statistical
methods. It is essential to be familiar with this methodology so to understand these papers. But you may learn these steps and methods
from the papers since all are based on the rules of designing scientific research projects. From a paper you may extract the principles as
well as you can follow immediately the realization. It is an excellent way to learn the methodology. You may even learn from the errors.
Block Two: Apply all these for your own research: make a study plan. It should include your study goal the extent and way of
your data collection the preliminary data processing the way of data analysis and the way of conclusion making.
Based on this outline you will prepare your own study design on your own student”s research work or on your thesis job. If you have no
such project at the moment you may construct an own “sample study plan” that can be a working model for your future thesis
work. You will have all help to find your own project and complete the plan in the practice if you need. All of your personal design
elements will be discussed and improved by a class discussion.
The practical realization of your study will be supported by the Data analysis 2 course.
Conditions for acceptance of the semester
Maximum 1 lesson absence.
Mid-term exams
Prepare and submit your own study plan step-by-step and present sortly weekly to the group - based on your active participation.
Making up for missed classes
One extra class
Reading material
- Obligatory literature
1-3 medical papers brought by each student (from library, from your department or from the tutor of your thesis).
- Literature developed by the Department
Other supporting materials supplied by the tutor of the classes.
- Notes
- Recommended literature
Any statistical books on study design and data analysis.
Lectures
1 Introduction. Find a paper to process. Find your own study.
Dr. Pótó László
2 The goal of your study - based on a demo paper
Dr. Pótó László
3 The main- and ‘sub-’hypotheses of the study.
Dr. Pótó László
4 Finding your sample frame - based on your hypotheses.
Dr. Pótó László
5 The research design and the methods of the data collection. How many data should be collected?
Dr. Pótó László
6 Creating the plan of the data analysis. The complete study plan.
Dr. Pótó László
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Practices
1 Introduction. Overview of some sample papers.
Dr. Pótó László
2 The goal of your study - processing a few papers brought and presented by students.
Dr. Pótó László
3 Setting the study hypotheses. Further analysis of the papers.
Dr. Pótó László
4 Which data should you collect and how to do that.
Dr. Pótó László
5 Finalize the plan of your data collection. Make a plan of the data processing.
Dr. Pótó László
6 Create, present and discuss of your study plan.
Dr. Pótó László
Seminars
Exam topics/questions
Preparation of the study plan
Participants
Dr. Pótó László (FIO4UU)
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211
OPE-FM2-T DATA ANALYSIS 2
Course director: DR. LÁSZLÓ PÓTÓ, associate professor
Institute of Bioanalysis [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the Basic module ▪ both semesters ▪ recommended semester: 7
Number of hours/semester: 6 lectures + 6 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 1 – 12 Prerequisites: OPE-FMA-T parallel
Topic
The goal of this course is to help students to prepare for thesis writing or making their own student research project. It covers two fields
of that job: the practice of data collection and prepare data for the analysis as well as the performing the analysis based on the preliminary
analysis plan. Shortly to say: How to perform the data collection and analysis of your own study project. (This course can be the
continuation of the ‘Data analysis 1” course however someone can complete these two courses on a reversed order as well. The
main reason of this flexibility is, that many students are asking for help when they have already had their data at hands (at least partially),
and this course is processing the steps from this point of the job. Even though, it is beneficial for the students doing this course first to
complete the Data analysis 1 course later. They can do it next year for example - so to understand the preliminary steps of a research
work: How to make a research plan?)
This course is also based on the medical papers. Students may pick the appropriate data collection methods and recognize the critical
points of this process based on the most fundamental papers of their own research field. They can learn from the most rewarded experts
on this way. From a paper you may extract the principles as well as you can follow immediately the realization. It is an excellent way to
learn the methodology. You may even learn from the errors.
The same way is followed for the data analysis and making conclusions. Every student will do his/her own data analysis based on their
own plan.
Students will have all help to the practical evaluation of their own data and making the right conclusion. The steps and results will be
discussed and improved by a class discussion.
Conditions for acceptance of the semester
Maximum 1 lesson absence.
Mid-term exams
Evaluate your data step by step and present it to the group weekly.
Making up for missed classes
One extra class
Reading material
- Obligatory literature
1-3 medical papers brought by each student (from library, from your department or from the tutor of your thesis).
- Literature developed by the Department
Supporting materials (papers, posters, research reports, ...) supplied by the tutor of the classes.
- Notes
- Recommended literature
Any statistical books.
Lectures
1 Introduction. Find a paper to process. Prepare or present your own data collection plan.
Dr. Pótó László
2 The realization of the data collection - examples are based on papers
Dr. Pótó László
3 The preliminary data preparations for the following statistical analysis.
Dr. Pótó László
4 Do your own statistical analysis 1-2: - select the right methods, - interpret the results.
Dr. Pótó László
5 Make your conclusion and share the results with the others.
Dr. Pótó László
6 Summary. Consolidation and evaluation of the results.
Dr. Pótó László
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212
Practices
1 Find a paper to process. Work on your own data collection plan.
Dr. Pótó László
2 Present the realization of the data collection - based on selected papers
Dr. Pótó László
3 Share your experiences on your preliminary data preparations - make corrections if needed.
Dr. Pótó László
4 Present your own statistical analysis - methods and results
Dr. Pótó László
5 Make your conclusion and share the results with the others.
Dr. Pótó László
6 Overview and summarize the results of the class.
Dr. Pótó László
Seminars
Exam topics/questions
Evaluate your data and submit your own results based on your active participation.
Participants
Dr. Pótó László (FIO4UU)
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213
OPE-DM5-T DEMONSTRATOR ACTIVITY 5
Course director: DR. LÁSZLÓ JÓZSEF CZOPF, associate professor
1st Department of Internal Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 7
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OPE-DM4-T completed
Topic
This course gives support and acknowledgement for students performing documented and successful supervised teaching activities and
taking an active part in organizing courses.
The subjects can be taken up in eight semesters (in a total value of 16 credits).
Conditions for acceptance of the semester
Students have to register every semester as demonstrators, should provide proof of previous demonstrator activity, and the semester will
be signed on the basis of at least 24 hours of teaching or organizatory activity. The grades will be given according to the Code of
Demonstrators with additional requirements, that you can reach using the following links: Code of Demonstrator Students:
https://docs.google.com/document/d/1xkkyeRdZcDphnqWEkpON0SQf34MpBBJqogG09foI8Rw/edit?usp=sharing
Faculty Home Page of the Circle of Demonstrator Students (DDK):
http://aok.pte.hu/en/egyseg/almenu/980/339
Mid-term exams
At least two midsemester tests should be successfully completed to pass.
Making up for missed classes
There are no absences accepted from the 24 hours demonstrator activity.
Reading material
- Obligatory literature
- Literature developed by the Department
..
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
The topics of the tests depend on the specific course of the demonstrator activity.
Participants
Dr. Czopf László József (BAVD1M), Dr. Koppán Ágnes Judit (ZAEQDO), Dr. Sebők Judit (GLM10L), Dr. Tamás Andrea (F7QM8G),
Dr. Ujvári Balázs (EN1LY9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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214
OPE-OPM-T ONLINE PHARMACEUTICAL MARKET AND THE DANGERS OF COUNTERFEIT MEDICINES
Course director: DR. ANDRÁS TAMÁS FITTLER, associate professor
Department of Pharmaceutics and University Pharmacy [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 7
Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OPG-GI1-T completed
Topic
Thousands of internet pharmacies are accessible on the web, and a vast number of illegitimate vendors overwhelm the market of online
pharmaceuticals. This illegal market segment operates within an uncontrolled environment, with no restrictions on vendors, consumers
or products, in which practically anyone can purchase any type of medication – including counterfeit drugs – without a prescription,
medical supervision or appropriate diagnosis, consequently compromising patient and medication safety. International and national
authorities lack efficient tools to discover and shut down illicit pharmacy websites and stop the illicit trade of counterfeit medicines.
Accordingly, advanced computational methods are needed to detect and mitigate cybercriminal activity, and efficient inter-disciplinary
communication and public awareness campaigns to inform consumers.
The course will provide insight into the current issues of the online pharmaceutical market and the dangers of counterfeit medicines. Real
world data on legitimate and rogue online pharmacies, various stakeholders, networks, products and information content will be
introduced, along with the discussion of measures combating illegal peddling of pharmaceuticals. Novel information technology and
data-science methods on the evaluation of this enormous online market will be discussed.
Students can access resources for their individual and group assignment, further the slides of the lectures and further reading material on
a designated web based interface (e.g. MS Teams and/or Neptun Meet Street).
Conditions for acceptance of the semester
Acceptance of term/semester:
- Regular attendance of classes, student should be able to work project-oriented and independently.
- Assignments and project work given in class should be carried out during term-time
- Presentation of project work
Mid-term exams
There are no midterm tests, however participants will present their individual and group assignments and prepare for their project work.
Making up for missed classes
Oportunity is possible following personal discussion.
Reading material
- Obligatory literature
- Literature developed by the Department
List of study aids to acquire curriculum and all presentations can be downloaded from MS Teams and/or Neptun MeetStreet.
- Notes
- Recommended literature
-Fittler András, Vida Róbert György, Káplár Mátyás, Botz Lajos: Consumers Turning to the Internet Pharmacy Market, JOURNAL
OF MEDICAL INTERNET RESEARCH 20: (8) e11115
- Vida Róbert György, Merczel Sára, Jáhn Eszter, Fittler András: Developing a framework regarding a complex risk based
methodology in the evaluation of hazards associated with medicinal products sourced via the internet, SAUDI PHARMACEUTICAL
JOURNAL 28: (12) pp. 1733-1742.
Lectures
1 Development and current issues of the online pharmacy market
Dr. Fittler András Tamás
2 Frequency and attitudes of consumers/patients purchasing medications online.
Dr. Fittler András Tamás
3 Current practice and legal framework of online drug distribution in Europe, international comparison
Dr. Fittler András Tamás
4 Facilitators of the online pharmacy market: self-medication, telemedicine, drug shortages, infodemic, etc.
Dr. Fittler András Tamás
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215
5 The role of the Falsified Medicines Directive in preventing falsified medicines entering the legal supply chain and reaching
patients
Dr. Fittler András Tamás
6 Evaluation of international pharmacy networks on the internet, applications of data science methods (lecturer: Prof. Dr Péter
Iványi, Faculty of Engineering and Information Technology)
Dr. Fittler András Tamás
7 Application of machine learning in identification of oral medicines to combat against falsified medicines and increase medication
safety
Dr. Feldmann Ádám
Practices
1 Nomenclature and categorization of online pharmacies. Identifying stakeholders of the market. (individual assignment)
Dr. Fittler András Tamás
2 Evaluation of the potential benefits and risks from various aspects. SWOT analysis from patient/consumer’s, authority and online
vendor’ perspective (group work)
Dr. Fittler András Tamás
3 Importance of the closed drug supply chain and identification of the global threats of integrity (group work)
Dr. Fittler András Tamás
4 The problem and prevalence of counterfeiting and falsifying of medicinal products – Introduction of project work on the
international significance of counterfeit drugs and potential countermeasures
Dr. Vida Róbert György
5 Technologies against counterfeit medicine. Introduction and assessment of national and international verification systems of
online vendors (group work)
Dr. Fittler András Tamás
6 Assessment of search engine result pages, online vendor characteristics and product information. Application of a complex risk
assessment methodology for project work.
Dr. Vida Róbert György
7 Presentation and discussion of project works: e.g. Evaluation of hazards associated with medicinal products sourced via the
internet, Fighting the global trade of counterfeit medicines, etc.
Dr. Vida Róbert György
Seminars
Exam topics/questions
End-of-the-term test is organized in Neptun Unipoll at the regular time of lectures. The test will be on the whole semester’s curriculum.
The end-of-the term test grade may be accepted as an examination grade, if passed. Assessment of the student performance is carried
out according to a five-grade scale:100-86,1% -excellent (5); 86-77,1% -good (4); 77-68,1% -satisfactory (3); 68-60,1% -pass (2);
and below 60,0% -fail (1) respectively.
Participants
Dr. Fittler András Tamás (IYR5HQ), Dr. Vida Róbert György (BN08GS)
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216
OPE-SHK-T DESIGN AND INDUSTRIAL MANUFACTURE OF MEDICINES
Course director: DR. SZILÁRD PÁL, assistant professor
Institute of Pharmaceutical Technology and Biopharmacy [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OPG-BFR-T completed + OPG-C2E-T completed
Topic
During the course, the process of the design of modified drug delivery systems is acquired by the students based on the theory and
practice of biopharmaceutical including examinations of dosage forms. The course consists of theoretical lectures and seminars.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Students have to write an end-semester assessment from the lectures at acceptance level of 60%.
Making up for missed classes
Students must fulfil requirements determined by the Code of Studies and Examinations. Student has make up for the missed lectures and
work reports.
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Leon Shargel, A. B.C. Yu, Stamford: Applied Biopharmaceutics and Pharmacokinetics
Susanna Wu-Pong, Yon Rojanasakul: Biopharmaceutical Drug Design and Development, Humana Press
Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel
Michael J. Rathbone, Michael S. Roberts: Modified-Release Drug Delivery Technology, Informa Healthcare
Michael E. Aulton: The Design and Manufacture of Medicines, Churchill Livingstone
Lectures
1 Floating drug delivery, Targeted Drug Delivery Systems
Dr. Pál Szilárd
2 Floating drug delivery, Targeted Drug Delivery Systems
Dr. Pál Szilárd
3 Floating drug delivery, Targeted Drug Delivery Systems
Dr. Pál Szilárd
4 Floating drug delivery, Targeted Drug Delivery Systems
Dr. Pál Szilárd
5 Introduction of modified drug delivery
Dr. Kása Péter
6 Introduction of modified drug delivery
Dr. Kása Péter
7 Introduction of modified drug delivery
Dr. Kása Péter
8 Introduction of modified drug delivery
Dr. Kása Péter
9 Targeted Drug Delivery Systems
Dr. Secenji Aleksandar
10 Targeted Drug Delivery Systems
Dr. Secenji Aleksandar
11 Targeted Drug Delivery Systems
Dr. Pál Szilárd
12 Targeted Drug Delivery Systems
Dr. Pál Szilárd
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217
13 Pulsative Drug Delivery Systems
Dr. Pál Szilárd
14 Pulsative Drug Delivery Systems
Dr. Pál Szilárd
15 Pulsative Drug Delivery Systems
Dr. Pál Szilárd
16 Pulsative Drug Delivery Systems
Dr. Pál Szilárd
17 Dissolution, lecture and practice
Dr. Lendvai Botond István
18 Dissolution, lecture and practice
Dr. Lendvai Botond István
19 Dissolution, lecture and practice
Dr. Pál Szilárd
20 Dissolution, lecture and practice
Dr. Pál Szilárd
21 From molecule to the preparition
Dr. Kása Péter
22 From molecule to the preparition
Dr. Kása Péter
23 From molecule to the preparition
Dr. Pál Szilárd
24 From molecule to the preparition
Dr. Pál Szilárd
25 3D printing in pharmaceutical technology
Kopcsányi Márton
26 3D printing in pharmaceutical technology
Kopcsányi Márton
27 Assessment
Dr. Pál Szilárd
28 Assessment
Dr. Pál Szilárd
Practices
Seminars
Exam topics/questions
Students can get the test topics in the institute or download the from website of the institute.
Participants
Dr. Kása Péter (ISWPRM), Dr. Lendvai Botond István (U0UI6H), Dr. Pál Szilárd (FYF5E9), Dr. Secenji Aleksandar (DI7BVF),
Kopcsányi Márton (D3S7AX)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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218
OPF-GTH-T GENE THERAPY
Course director: DR. GÉZA SÁFRÁNY, visiting professor
Institute of Laboratory Medicine [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ spring semester ▪ recommended semester: 8
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 3 – 30 Prerequisites: -
Topic
We wish to give a short overview about the present state of gene therapy, the current ongoing clinical trials and the potential side effects
of gene therapy and about the ethical considerations. The various viral and non-viral gene delivery protocols suitable for high efficiency
gene delivery both under in vitro and in vivo conditions will be discussed in details. Gene therapy protocols applied in the treatment of
malignant diseases will be presented together with the results of ongoing clinical trials. We will talk about the results and the potentials
of the treatments of inherited genetic disorders. One of the most promising field of the current clinical trials is the treatment of ischemic
diseases, the results will be presented. The potential applications of stem cells during gene therapy will be described, as well. Finally, we
will discuss the side effects occurring during gene therapy and the ethical considerations will also be mentioned.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
1 Test
Making up for missed classes
Joining later lectures, individual consultations.
Reading material
- Obligatory literature
1. Kelly K. Hunt, Stephan A. Vorburger and Stephen G. Swisher (ed.): Gene Therapy for Cancer, 2007 Humana Press Inc. 999
Riverview Drive, Suite 208 Totowa, New Jersey 07512
2. Thomas F. Kresina (ed.): Introduction to Molecular Medicine and Gene Therapy, 2001 by Wiley-Liss, Inc. ISBNs: 0-471-39188-
3 (Hardback); 0-471-22387-5 (Electronic)
- Literature developed by the Department
1. Sáfrány G.: A génterápia génsebészeti alapjai és jelenlegi helyzete, A Genom (ed.: Hídvégi EJ), Budapest, Széphalom
Könyvműhely 2003, pp 187-204
2. Sáfrány G.: A vasculáris génterápia és a csontvelőőssejt-terápia, Atherosclerosis (ed.: Császár A.), Budapest, Synergo Kiadó,
2004 pp 336-344
- Notes
- Recommended literature
http://www.genetherapynet.com/clinicaltrialsgov.html
http://www.bioportfolio.com/cgi-bin/acatalog/Human_Gene_Therapy_Course.html
http://openlearn.open.ac.uk/course/view.php?id=2430
Lectures
1 Introduction to gene therapy, ongoing clinical trials
Dr. Sáfrány Géza
2 Gene delivery protocols, viral vectors applied in gene therapy
Dr. Sáfrány Géza
3 Targeted gene delivery and targeted gene expression
Dr. Sáfrány Géza
4 Application of dendritic cells in gene therapy
Dr. Sáfrány Géza
5 Gene directed enzyme pro-drug therapy of malignant diseases
Dr. Sáfrány Géza
6 Immune therapy of malignant diseases
Dr. Sáfrány Géza
7 Gene therapy of leukaemia
Dr. Sáfrány Géza
8 Treatment of immune-deficiencies with gene therapy
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219
Dr. Sáfrány Géza
9 Gene therapy of ischemic diseases
Dr. Sáfrány Géza
10 Gene therapy of cystic fibrosis
Dr. Sáfrány Géza
11 Gene therapy of thalassemia
Dr. Sáfrány Géza
12 Oncolytic viruses in tumor therapy
Dr. Sáfrány Géza
Practices
Seminars
Exam topics/questions
Multiple choice tests for checking the acquisition of course material is given at the end of semester. Questions include material discussed
in lectures and seminars.
Participants
Dr. Sáfrány Géza (UYX8V2)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
220
OPE-DM6-T DEMONSTRATOR ACTIVITY 6
Course director: DR. LÁSZLÓ JÓZSEF CZOPF, associate professor
1st Department of Internal Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 8
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OPE-DM5-T completed
Topic
This course gives support and acknowledgement for students performing documented and successful supervised teaching activities and
taking an active part in organizing courses.
The subjects can be taken up in eight semesters (in a total value of 16 credits).
Conditions for acceptance of the semester
Students have to register every semester as demonstrators, should provide proof of previous demonstrator activity, and the semester will
be signed on the basis of at least 24 hours of teaching or organizatory activity. The grades will be given according to the Code of
Demonstrators with additional requirements, that you can reach using the following links: Code of Demonstrator Students:
https://docs.google.com/document/d/1xkkyeRdZcDphnqWEkpON0SQf34MpBBJqogG09foI8Rw/edit?usp=sharing
Faculty Home Page of the Circle of Demonstrator Students (DDK):
http://aok.pte.hu/en/egyseg/almenu/980/339
Mid-term exams
At least two midsemester tests should be successfully completed to pass.
Making up for missed classes
There are no absences accepted from the 24 hours demonstrator activity.
Reading material
- Obligatory literature
- Literature developed by the Department
..
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
The topics of the tests depend on the specific course of the demonstrator activity.
Participants
Dr. Czopf László József (BAVD1M), Dr. Koppán Ágnes Judit (ZAEQDO), Dr. Sebők Judit (GLM10L), Dr. Tamás Andrea (F7QM8G),
Dr. Ujvári Balázs (EN1LY9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
221
OPE-DRO-T DRUG AND SUBSTANCE ABUSE
Course director: DR. ERIKA SÁNTICS-PINTÉR, professor
Department of Pharmacology and Pharmacotherapy [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 8
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OPG-D1E-T completed
Topic
The course aimed to provide general terms of drug and substance abuse and present its physiological and biochemical background. We
are going to review systematically the most important pharmacological features of the drugs of abuse, the symptoms, dangers and possible
treatments of abuse. The drugs are discussed in the following sections: opioids, anxiolytics, sedatohypnotics, inhalants, alcohol,
psychomotor stimulants (amphetamin and derivates, cocain, coffein, nicotin), psychedelics and hallucinogens (LSD, mescalin,
phencyclidin), cannabis. After the discussion of pharmacology the participants can hear about the practical problems of drug abuse. At
the end of the course the students should present 5-10 minute ppt presentations from different abuse-related topics.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
There is no possibility.
Making up for missed classes
There is no possibility.
Reading material
- Obligatory literature
- Literature developed by the Department
Uploaded on the Neptun
- Notes
- Recommended literature
Lectures
1 General terms of drug abuse, definition of dependence and tolerance
Sánticsné Dr. Pintér Erika
2 General terms of drug abuse, definition of dependence and tolerance
Sánticsné Dr. Pintér Erika
3 Opioid abuse
Dr. Horváth Ádám István
4 Abuse of anxiolytics and sedatohypnotics. Inhalants.
Dr. Horváth Ádám István
5 Alcohol abuse
Dr. Horváth Ádám István
6 Abuse of psychomotor stimulants
Dr. Horváth Ádám István
7 Psychedelics, hallucinogens, cannabis
Sánticsné Dr. Pintér Erika
8 Designer drugs
Sánticsné Dr. Pintér Erika
9 Practical problems of drug abuse
Dr. Szemelyácz János
10 Practical problems of drug abuse
Dr. Szemelyácz János
11 Presentations of students
Sánticsné Dr. Pintér Erika
12 Written exam
Sánticsné Dr. Pintér Erika
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
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222
Practices
Seminars
Exam topics/questions
1. General terms of drug abuse, definition of dependence and tolerance
2. Opioid abuse
3. Abuse of anxiolytics and sedatohypnotics. Inhalants.
4. Alcohol abuse
5. Abuse of psychomotor stimulants
6. Psychedelics, hallucinogens, cannabis
7. Designer drugs
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
223
OPE-FAJ-T PAIN AND ANALGESICS
Course director: DR. GÁBOR ISTVÁN PETHŐ, professor
Department of Pharmacology and Pharmacotherapy [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 8
Number of hours/semester: 10 lectures + 0 practices + 0 seminars = total of 10 hours
Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OPG-D1E-T completed
Topic
The aim of the course is to give an integrative overview on the physiological, pathophysiological and pharmacological aspects of pain.
Major tasks are to (i) provide information on peripheral and central mechanisms of pain and hyperalgesia; (ii) describe the major features
of existing analgesics including opioids, non-steroidal antiinflammatory agents and adjuvant analgesics; (iii) outline novel targets for
development of analgesic drugs. The course will also help students prepare for the exams in Pharmacology 2 and 3.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
After the last lecture of the course, a written test is taken in the instruction period to obtain a mid-semester grade. Those who fail or do
not write this test have a second chance until end of Week 12 of the instruction period to improve in form of an oral conversation. Upon
failing or missing there is one more oral chance to obtain a mid-semester grade during the first two weeks of the exam period.
Making up for missed classes
There is no way to make up for missed lectures.
Reading material
- Obligatory literature
None.
- Literature developed by the Department
The material of the lectures is available in PDF format in the Neptun.
- Notes
None.
- Recommended literature
None.
Lectures
1 Basic terms related to pain and nociceptors
Dr. Pethő Gábor István
2 Features of capsaicin-sensitive nociceptors
Dr. Pethő Gábor István
3 Peripheral mechanisms of hyperalgesia
Dr. Pethő Gábor István
4 Central mechanisms of hyperalgesia and allodynia
Dr. Pethő Gábor István
5 Features of neuropathic pain
Dr. Pethő Gábor István
6 Pharmacology of opioid analgesics
Dr. Pethő Gábor István
7 Pharmacology of non-steroidal antiinflammatory analgesic drugs
Dr. Pethő Gábor István
8 Adjuvant analgesics
Dr. Pethő Gábor István
9 New targets for development of analgesics I
Dr. Pethő Gábor István
10 New targets for development of analgesics II
Dr. Pethő Gábor István
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
224
Practices
Seminars
Exam topics/questions
No exam questions are given. The essay questions of the written exam are based on the material presented.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
225
OPE-MGT-T PHARMACEUTICAL TECHNOLOGY OF MODIFIED DRUG RELEASE
Course director: DR. SZILÁRD PÁL, assistant professor
Institute of Pharmaceutical Technology and Biopharmacy [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 8
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OPG-C4E-T parallel
Topic
Students can get acquainted in details with modified drug delivery technologies and special industrial drug manufacture (3D printing,
manufacture of multi-layer tablets and osmotic preparations) and the importance of pharmaceutical excipients. Student will learn special
manufacturing technologies through the demonstration of dosage forms already available in the pharmaceutical therapy.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
During the end semester test 60 % should be reached.
Making up for missed classes
According to the Code of Studies and Examinations
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, 2011
Lectures
1 Theory of modified drug release
Dr. Pál Szilárd
2 Importance of excipients, patents of excipient-compositions
Dr. Kása Péter
3 Immediate drug-release (OraSolv, DuraSolv, Zydis technology)
Dr. Pál Szilárd
4 Sustained drug-release: Multiparticulate dosage forms I. (sustained release pellets in practice)
Dr. Pál Szilárd
5 Multiparticulate dosage forms II. (MUPS technology)
Dr. Pál Szilárd
6 Matrix systems I. (hydrophilic matrices)
Dr. Pál Szilárd
7 Matrix systems II. (hydrophobic matrices)
Dr. Pál Szilárd
8 Osmotic technology (EOP, OROS, L-OROS, GITS)
Dr. Pál Szilárd
9 Geometry based drug-release (Geomatrix, Procise, Smartrix technology)
Dr. Kása Péter
10 Chronotherapeutic systems (Geoclock technology)
Dr. Pál Szilárd
11 3D printing in the field of modified drug delivery
Dr. Pál Szilárd
12 Site specific drug release (gastroretentive systems, colon-specific drug delivery)
Dr. Pál Szilárd
13 Halving of tablets, technology of halving-friendly tablets, concept of ,,ghost” tablets
Dr. Kása Péter
14 End-year test
Dr. Pál Szilárd
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
226
Practices
Seminars
Exam topics/questions
http://gytk.pte.hu
Participants
Dr. Kása Péter (ISWPRM), Dr. Pál Szilárd (FYF5E9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
227
OPE-IVF-T INFECTIONS AND IMMUNITY
Course director: DR. JÚLIA BARTHÓ-SZEKERES, professor
Department of Medical Biology and Central Electron Microscope Laboratory [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ spring semester ▪ recommended semester: 8
Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 2 – 25 Prerequisites: OPO-IMM-T completed + OPO-MI1-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
The importance of anti-infectious immunity is not restricted to elimination of pathogens, but is also responsible for long lasting protection,
as well as -in some cases- immunopathological disorders
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Continuous
Making up for missed classes
Consultation
Reading material
- Obligatory literature
- Literature developed by the Department
Lecture slides
- Notes
- Recommended literature
1. H. Chapel, M. Haeney, N. Misbah, Snowden: Clinical Immunology, Blackwell, 2008
2. S. Kartikeyan, R.N. Bharmal, R.P. Tiwari, and P.S. Bisen: HIV and AIDS: Basic Elements and Priorities, 2007
3. T. Platts-Mills and Johannes Ring: Allergy in Practice, 2003
Lectures
1 Non-specific defence. Surface barriers, normal colonizing flora, phagocytosis, complement system.
Dr. Barthóné Dr. Szekeres Júlia
2 Non-specific defence. Surface barriers, normal colonizing flora, phagocytosis, complement system.
Dr. Barthóné Dr. Szekeres Júlia
3 Antigen presentation and recognition. Dendritic cells, pattern recognition receptors.
Dr. Barthóné Dr. Szekeres Júlia
4 Antigen presentation and recognition. Dendritic cells, pattern recognition receptors.
Dr. Barthóné Dr. Szekeres Júlia
5 Defence against extracellular microorganisms. The role of immunoglobulin classes. Mucosal immunity.
Dr. Barthóné Dr. Szekeres Júlia
6 Defence against extracellular microorganisms. The role of immunoglobulin classes. Mucosal immunity.
Dr. Barthóné Dr. Szekeres Júlia
7 Defence against intracellular microorganisms. Defence against viral infections. Viruses and immunosuppression.
Dr. Barthóné Dr. Szekeres Júlia
8 Defence against intracellular microorganisms. Defence against viral infections. Viruses and immunosuppression.
Dr. Barthóné Dr. Szekeres Júlia
9 Defence against parasitic infections. Micro-and macroparasite infections that polarize the immune response.
Dr. Barthóné Dr. Szekeres Júlia
10 Defence against parasitic infections. Micro-and macroparasite infections that polarize the immune response.
Dr. Barthóné Dr. Szekeres Júlia
11 Evasion and use of the innate and adaptive immune responses by microorganisms.
Dr. Barthóné Dr. Szekeres Júlia
12 Evasion and use of the innate and adaptive immune responses by microorganisms.
Dr. Barthóné Dr. Szekeres Júlia
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
228
13 Healing of infectious diseases. The pathogenic role of anti-infectious immunity; local inflammation, systemic inflammation,
sepsis, endotoxin shock, toxic shock syndrome.
Dr. Barthóné Dr. Szekeres Júlia
14 Healing of infectious diseases. The pathogenic role of anti-infectious immunity; local inflammation, systemic inflammation,
sepsis, endotoxin shock, toxic shock syndrome.
Dr. Barthóné Dr. Szekeres Júlia
15 The pathogenic role of anti-infectious immunity; hypersensitivity reactions in bacterial-parasitic and fungal infections.
Dr. Barthóné Dr. Szekeres Júlia
16 The pathogenic role of anti-infectious immunity; hypersensitivity reactions in bacterial-parasitic and fungal infections.
Dr. Barthóné Dr. Szekeres Júlia
17 Induction of autoimmunity; molecular mimicri, epitope spreading, polyclonal T or B cell activation.
Dr. Barthóné Dr. Szekeres Júlia
18 Induction of autoimmunity; molecular mimicri, epitope spreading, polyclonal T or B cell activation.
Dr. Barthóné Dr. Szekeres Júlia
19 Immunopathological alterations following viral infections. The involvement of CD8+ T cells.
Dr. Barthóné Dr. Szekeres Júlia
20 Immunopathological alterations following viral infections. The involvement of CD8+ T cells.
Dr. Barthóné Dr. Szekeres Júlia
21 Immunopathological alterations following viral infections. The involvement of CD4+ T cells.
Dr. Barthóné Dr. Szekeres Júlia
22 Immunopathological alterations following viral infections. The involvement of antibodies.
Dr. Barthóné Dr. Szekeres Júlia
23 Vaccination; Type of vaccines, requirements for vaccines.
Dr. Barthóné Dr. Szekeres Júlia
24 Vaccination; rational vaccine development, mandatory vaccines.
Dr. Barthóné Dr. Szekeres Júlia
Practices
Seminars
Exam topics/questions
The same as lecture topics
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
229
OPF-SUO-T EMERGENCY MEDICINE
Course director: DR. PÉTER LÁSZLÓ KANIZSAI, associate professor
Department of Emergency Medicine [email protected]
1 credit ▪ midsemester grade ▪ Optional subject ▪ autumn semester ▪ recommended semester: 9
Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours
Course headcount limitations (min.-max.): 5 – 150 Prerequisites: OPO-KL1-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
It is prudent to understand the emergency concept for health care providers not involved in acute care. The purpose of the subject is to
understand the aims and principles of emergency care, to get familiar with emergency approach based on focused assessment and care,
risk stratification. It is also important to understand the essences of team approach and make patients comfortable by providing safe and
patient centered care within our given time-range, i.e. 24 hours.
Conditions for acceptance of the semester
Test exam.
Mid-term exams
Making up for missed classes
Personal communication with the tutors.
Reading material
- Obligatory literature
R. Aghababian: Essentials of Emergency Medicine, 2nd edition
- Literature developed by the Department
- Notes
- Recommended literature
Lectures
1 History of emergency care, emergency aspects, structured communication
Dr. Kanizsai Péter László
2 Prehospital care
Dr. Bóna Ernő
3 Triage, teamwork
Dr. Kanizsai Péter László
4 Emergency group of symptoms
Dr. Szilágyi Csilla
5 Pain syndromes
Dr. Labudek Renáta
6 From door to needle (ACS and stroke care - emergency aspects)
Dr. Merész Márton
7 Environmental emergencies
Dr. Sparas Ákos
8 Care of the severely injured
Dr. Kanizsai Péter László
9 Paediatric emergency care
Dr. Bánfai Gábor László
10 Toxicology basics
Dr. Bóna Ernő
11 Sepsis in the emergency department
Dr. Kanizsai Péter László
12 Interactive consultation between the Hungarian university emergency departments
Dr. Kanizsai Péter László
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
230
Practices
Seminars
Exam topics/questions
Website of Emergency Medicine, University of Pécs.
Participants
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
231
OPE-DM7-T DEMONSTRATOR ACTIVITY 7
Course director: DR. LÁSZLÓ JÓZSEF CZOPF, associate professor
1st Department of Internal Medicine [email protected]
2 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ both semesters ▪ recommended semester: 9
Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours
Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OPE-DM6-T completed
Topic
This course gives support and acknowledgement for students performing documented and successful supervised teaching activities and
taking an active part in organizing courses.
The subjects can be taken up in eight semesters (in a total value of 16 credits).
Conditions for acceptance of the semester
Students have to register every semester as demonstrators, should provide proof of previous demonstrator activity, and the semester will
be signed on the basis of at least 24 hours of teaching or organizatory activity. The grades will be given according to the Code of
Demonstrators with additional requirements, that you can reach using the following links: Code of Demonstrator Students:
https://docs.google.com/document/d/1xkkyeRdZcDphnqWEkpON0SQf34MpBBJqogG09foI8Rw/edit?usp=sharing
Faculty Home Page of the Circle of Demonstrator Students (DDK):
http://aok.pte.hu/en/egyseg/almenu/980/339
Mid-term exams
At least two midsemester tests should be successfully completed to pass.
Making up for missed classes
There are no absences accepted from the 24 hours demonstrator activity.
Reading material
- Obligatory literature
- Literature developed by the Department
..
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
The topics of the tests depend on the specific course of the demonstrator activity.
Participants
Dr. Czopf László József (BAVD1M), Dr. Koppán Ágnes Judit (ZAEQDO), Dr. Sebők Judit (GLM10L), Dr. Tamás Andrea (F7QM8G),
Dr. Ujvári Balázs (EN1LY9)
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
232
OPE-GST-T SPECIAL FIELDS OF PHARMACOLOGY
Course director: DR. GÁBOR ISTVÁN PETHŐ, professor
Department of Pharmacology and Pharmacotherapy [email protected]
1 credit ▪ midsemester grade ▪ Elective subject for the medical-biological module ▪ autumn semester ▪ recommended semester: 9
Number of hours/semester: 10 lectures + 0 practices + 0 seminars = total of 10 hours
Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OPG-D1E-T completed
Topic
The aim of the course is to present those fields of pharmacology that are not covered at all or only partially discussed in the compulsory
courses Pharmacology 1-2-3 because of time limits. These are the following: use of drugs during pregnancy and lactation; significance
of pharmacogenomics in therapy and drug development, pharmacology of retinoids; other drugs used in dermatology; use of meta-
analysis in evaluation of drugs, clinical significance of basic pharmacodynamic and pharmacokinetic parameters; special aspects of drugs
used by inhalation, basics of chronopharmacology; pharmacology of contrast media, drugs and chirality. The course wishes to contribute
to a better understanding of the use of drugs in the clinical practice and may help students prepare for the pharmacology exams.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
After the last lecture of the course, a written test is taken in the instruction period to obtain a mid-semester grade. Those who fail or do
not write this test have a second chance until the end of Week 12 of the instruction period to improve in form of an oral conversation.
Upon failing or missing there is one more oral chance to obtain a mid-semester grade during the first two weeks of the exam period.
Making up for missed classes
There is no way to make up for missed lectures.
Reading material
- Obligatory literature
None.
- Literature developed by the Department
The material of the lectures is available in PDF format in the Neptun.
- Notes
None.
- Recommended literature
None.
Lectures
1 Special aspects of use of drugs during pregnancy and lactation
Dr. Pethő Gábor István
2 Significance of pharmacogenomics in therapy and drug development
Dr. Pethő Gábor István
3 Use of meta-analysis in evaluation of drugs
Dr. Pethő Gábor István
4 Drugs and chirality
Dr. Pethő Gábor István
5 Clinical significance of pharmacodynamic and pharmacokinetic parameters on the example of drugs used in respiratory diseases
I
Dr. Pethő Gábor István
6 Clinical significance of pharmacodynamic and pharmacokinetic parameters on the example of drugs used in respiratory diseases
II
Dr. Pethő Gábor István
7 Pharmacology of retinoids
Dr. Pethő Gábor István
8 Drugs (other than retinoids) used in dermatology
Dr. Pethő Gábor István
9 Pharmacology of contrast media
Dr. Pethő Gábor István
10 Basics of chronopharmacology
UP FP Pharmacy major – Elective and Optional subjects - Course descriptions – academic year of 2021/2022
Editing of this publication was closed on July 20, 2021. For the most up-to-date version of course descriptions, please see the subject's web page - in the Education section of the host organizational unit
233
Dr. Pethő Gábor István
Practices
Seminars
Exam topics/questions
No exam questions are given. The essay questions of the written exam are based on the material presented.
Participants