5’ 3’331*1*

TSS

1515DNA of Ct-OATP1B3 124 125124-2

mRNA of Ct-OATP1B3 331*1* 1515124 125 12 331*1* 1515124 125 12124-2

Alternative Splicing

Start Codon Stop Codon Start Codon Stop Codon

Mature Protein of Ct-OATP1B3(674 amino acid)

Immature Protein(91 amino acid)

Translation Translation

Transcription

Supplemental Figure 1. Alternative splicing of Ct-OATP1B3.Exons of Ct-OATP1B3 are indicated by open boxes. TSS, transcription start site. The mature Ct-OATP1B3 is a 674-amino acid polypeptide, while another variant possesses the terminal codon in the exon 4-2, producing immature 91-amino acid polypeptide.