DEPARTMENT OF TECHNICAL EDUCATION ANDRA PRADESHName of the Staff: Y.Venkat ReddyDesignation: Sr. Lecturer Branch: Packaging TechnologyInstitute: J.N.G.P. Ramanthapur, Hyd Subject: Drug & Pharmaceutical PackagingSubject Code: PKG.503Topic: Introduction to Drug Packaging Sub topic: Preparation of Dosage formDuration: 100 minutesTeaching Aid: PPT, Animations & Photographs

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In the last class we have learntThe Concept Classification of Pharmaceuticals.Preparation of Tablets.Recap

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On the completion of the topic the student will able to understandThe Concept of Various Dosages PreparationsObjectives:

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A capsule is a hard or soft ,water soluble that contains a powder or liquid. Hard Gelatin Soft Gelatin

Capsules:

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Hard Gelatin Capsules

Empty Capsule Storage Controlled temperature and humidityToo moist capsules become tackyToo dry capsules become brittle and change dimensions30 to 45% R.M. ideal

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Operations Rectify the capsule Separate body from cap Fill the body Replace the capCapsule Filling Machine Hand Operated Semi-automatic Fully automatic

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Capsule filling machine

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SuppositoriesRectal

Non rectal

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LiquidsEmulsions

Suspensions

Oral liquids

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Nasal, Inhalant, Ophthalmic, Otic liquids

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Parenterals and IV fluidsThe parenteral routes are the principal routes for the systemic delivery of drugs.

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Lozenzes

Having sugar base, much harder than tabletsDo not require much mechanical protection

PillsReplaced by tabletsSimilar packaging to Tablets

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GelA semisolid emulsion or suspensionContains a gelling agent in sufficient quantities to impart a 3-dimensional, cross-linked matrixProvides a cooling sensation when applied to the skinUsually translucent and non-greasy

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PasteA semisolid suspensionContains a large proportion (i.e., 20-50%) of solids finely dispersed in an aqueous or fatty vehicleOpaque, viscous, greasy to mildly greasyAdheres well to the skin, forming a protective layer

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LotionA liquid emulsionGenerally contains a water-based vehicle with > 50% of volatilesHas sufficiently low viscosity that it may be pouredOpaque and non-greasyTends to evaporate rapidly with a cooling sensation when applied to the skin

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OintmentsTopicalOpthalmicA semisolid emulsion or suspensionGenerally contains > 50% of hydrocarbons or PEGs as the vehicle and < 20% of volatilesOpaque or translucent, viscous, greasyTends not to evaporate or be absorbed when applied to the skin

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CreamA semisolid emulsion or suspensionGenerally contains < 50% of hydrocarbons or PEGs as the vehicle and/or > 20% of volatilesOpaque, viscous, non-greasy to mildly greasyTends to mostly evaporate or be absorbed when applied to the skinCan be hydrophilic or lipophilic

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We have learnt Capsules: A capsule is a hard or soft ,water soluble that contains a powder or liquid. These are of Hard Gelatin Or Soft Gelatin.

Summary

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Various medications available areSyrups, Tablets, Capsules,

Summary

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Lotions ,Ointments,Creams, Gels, paste , Lozenzes, liquids ,Parenterals

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1. A Capsule is a a) Hard Gelatin b) Soft Gelatin c) a and b of above d) either a or b of above

Quiz

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2. Liquid medications are a) Emulsions b) Suspensions c) Oral liquids d) Lozenzes e) All of the above Quiz

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How the capsules are filled and sealed ?Explain the preparation of various dosage forms .What are the various types of medications available.Frequently asked Questions

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