end-station construction of x-ray phase contrast imaging
TRANSCRIPT
End-station construction of X-ray phase contrast imaging
on the basis of compact accelerators
Oleksandr Lebed
KT Forum on Medical Applications
25 Sep 2018
Outline
Motivation
Realization of X-ray phase contrast imaging
X-ray sources on the basis of compact accelerators
Summary
2O. Lebed, KT Forum on Medical Applications, SEP 25, End-station of PCI on compact accelerators
Motivation
Improving diagnostic and treatment methods for cancer is
one of the most urgent issues in applied science and medicine.
X-ray phase contrast imaging (PCI) is presented as one of
the most promising methods of medical diagnostics
X-ray sources on the basis of compact accelerators have
advantages in terms of wide application and market potential
3O. Lebed, KT Forum on Medical Applications, SEP 25, End-station of PCI on compact accelerators
Phase-contrast X-ray imaging (PCI) is a general term for different technical methods that use information concerning changes in the phase of an X-ray beam that passes through an object in order to create its images.
the phase shift
an exponential decay factor decreasing the amplitude of the wave
4k 2k
4O. Lebed, KT Forum on Medical Applications, SEP 25, End-station of PCI on compact accelerators
Phase-contrast X-ray imaging
The practical implementation of X-ray phase contrast methods imposes significant requirements on the characteristics of all elements of the facility.
Experimental implementation of PCI
X-ray source Object of research Detectors
Realization of X-ray phase contrast imaging
Type of source
Geometric size
Intensity
Monochromaticity
Spot size
Photon energy
Cost
System of precision
movement
Processing and
improvement of image
Principle of action
Resolution
SensitivitySize of the object
Distance to source and detector
Elements of X-ray optics
(if necessary)
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Laboratory of Linear Accelerators in Orsay, France (LAL)Institute of Applied Physics of NAS of Ukraine in Sumy, Ukraine (IAP)
Realization of X-ray phase contrast imaging
6O. Lebed, KT Forum on Medical Applications, SEP 25, End-station of PCI on compact accelerators
ThomX project, LALX-ray Source at IAPCTF3, CERN
Medipix
Geant IV,FLUKA
Examples of PCI pictures
Т. Tuohimaa, М. Otendal and Н.М. Hertz, Appl. Phys. Lett. 91, 074104 (2007)
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Accelerators based compact source
of quasi-monochromatic X-ray at IAP NASU
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ThomX Compton backscattering X-ray source
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• Electrons:- 20-70 MeV - 20ps rms
• Laser:- 30mJ/pulse => 100kW - 1ps rms
• X-rays:- 6-92keV- 1011 to 1013 ph/s
21 1 /iE
mc
Main range of radiation angle
Summary
10
X-ray phase contrast imaging is presented as one of the most
promising techniques for improving diagnostic and treatment
methods for cancer.
The practical implementation of X-ray phase contrast methods
imposes significant requirements on the characteristics of all
elements of the facility. There is a need to use modern CERN
technology
The development of X-ray phase-contrast imaging on the basis of
compact accelerators has several advantages: quality of X-ray,
flexibility of use, cost, wide area of application, etc.
O. Lebed, KT Forum on Medical Applications, SEP 25, End-station of PCI on compact accelerators
Thank you for attention!