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#PIWorld ©2019 OSIsoft, LLC Enterprise PI and the Digital Plant Wilfred Mascarenhas Greg White 1

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Page 1: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

Enterprise PI and the Digital Plant

Wilfred Mascarenhas

Greg White

1

Page 2: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

2

Agenda

• Introductions and About Eli Lilly and Company

• Digital Plant Vision and Business Challenge

• Enterprise PI as a Key Strategy

• Implementation Details

• Use Case – Global Energy Dashboard

• Conclusion

• Q&A

Page 3: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

3

Global Fast Facts

Clinical research conducted

in more than 55 countries

Research and development

facilities located in 8 countries

Manufacturing plants located in 8 countries

Products marketed in 120 countries

Approximately 38,000 employees worldwide

More than 8,000 employees engaged

in research and development

Headquarters located in

Indianapolis, Indiana, U.S.A.

A heritage more than 140 years strong,

founded on May 10, 1876

Page 4: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

4

A Heritage of Discovery

Page 5: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Financials

NET SALES $ 24,555.7

NET INCOME AS REPORTED $ 3,232.0

NET INCOME (NON-GAAP) $ 5,734.6

EARNINGS/SHARE AS REPORTED $ 3.13

EARNINGS/SHARE (NON-GAAP) $ 5.55

DIVIDENDS PAID PER SHARE AS REPORTED $ 2.25

(dollars in millions except for per-share data)

Page 6: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Our Strategy

5

MOLECULE AND

INDICATIONS IN

REGULATORY

REVIEW

Our fundamental strategy is predicated on discovering new medicines. Lilly currently has one of the most robust mid-to-late stage pipelines in its history.

19

MOLECULES AND

INDICATIONS IN

PHASE 3 CLINICAL

DEVELOPMENT

16

MOLECULES AND

INDICATIONS IN

PHASE 2 TESTING

23

MOLECULES AND

INDICATIONS IN

PHASE 1 TESTING

*Numbers updated February 5, 2019

Page 7: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

7

Our Global Presence

Updated: November 6, 2018

Page 8: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Digital Plant

Industrie 4.0 = Strategic Initiative by German Government (Working Group Recommendations initially published in 2013)

Page 9: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Enabling the Digital Plant Vision

Digital Plant

Process

People Technology

Page 10: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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DP Process : Innovation Flow

Prioritization

Opportunity Identification

Establish Goals

Proof of Concept

Pilot Optimize Deploy Establish

Goals Proof of Concept

Pilot Optimize Deploy

Evaluate & Conceptual

Design

Proof of Concept

Pilot Deploy Optimize & Replicate

Value Assessment

Facilitate across the organization

Sanctioning Process Scale

Rapidly Track

Value

Page 11: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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DP – People Strategy

•Changing the culture

•Upskilling the workforce

Page 12: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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DP – Role of Technology

•Cyber Security

•Big data and analytics

•Robotics

Page 13: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Digital Plant Vision – Centralized Data Architecture

Hadoop

(Staging)

Analytics

Data

warehouse

Enterprise

PI

Historian

Centralized Data Storage

Governance Data Models Data Quality

Data Contextualization Security Master Data

Da

ta …

….

Da

ta …

….

Da

ta …

….

Da

ta …

….

Faster

Business

Outcomes

(Ability to scale

from POC to Prod

across all mfg

sites).

Page 14: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Value of the EA

Page 15: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Innovation with the EA

• Removes activation barrier for collecting data and utilizing advanced analytics

• Price is not an excuse

• Faster adoption of newer tools such as PI Vision and AF/EF lead to better analysis and understanding of manufacturing data

• Removes limitation of who has access to tools Removes limitation on who can innovate

• Provides ability to innovate in a non-GMP environment before applying to GMP environment

Page 16: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Standardization with the EA

• Single integration point for process data

• Standard metadata

• Reuse / Replication

• Additional savings

• Avoid duplicate work

Page 17: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Enterprise PI and Advanced Analytics

Prod Pilot POC

Prod Pilot POC

Release 1

(Dashboard)

Release 2

(Predictive)

We can continue to innovate and apply advanced analytics to one pilot site whilst

the other sites are still being implemented.

Page 18: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Business Need

Multiple sites with diverse energy assets and data capabilities

• No standard energy monitoring or reporting

• Various capacities, configurations, automation, data

• Regional climates and HVAC design philosophies

• Energy savings opportunities identified through manual investigation

Implement Energy Dashboard to provide:

• Energy monitoring across the enterprise

• Standard KPI reporting and benchmarking

• Energy fault detection

Page 19: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Technology Selection

Options Investigated

• Commercial Off The Shelf (COTS) software: monitoring / fault ID / optimization

• Custom development within local automation systems

OSIsoft PI System selection

• Asset Framework (AF) functionality

• Standard energy performance and fault identification logic

• Templates for replication to all sites

• Leverage the EA to reduce local costs & resource requirements

• 1 interface for company wide energy data (standard naming)

• Integrate manufacturing and energy data

Page 20: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

Energy Dashboard – Design

Page 21: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Energy Data

Common energy data collected for all sites • Site and building consumption

• Generation systems: boilers - chilled water - compressed air

• Air Handling Unit (AHU) systems

Building Meters Generation Systems AHUs

Electric Input Energy Inlet Air Temp

Steam Energy Delivered Heating Air Temp

Chilled Water Calculate COP Cooling Air Temp

Compressed Air Valve Positions

Calculate Energy & Faults

Page 22: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Energy Calculations

KPI parameters

AHU air temperature faults

Economizer Operation Simultaneous Heating/Cooling

Over Heating Over Cooling

100% Conditions

Boiler Input Fuel/Output Steam or COP

Chilled Water kw/Ton or COP

AHU’s BTU/cfm

• All calculations standardized on Analysis Templates in AF

Page 23: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Monitoring

CHW System Consumption &

Performance

Individual Chiller Consumption &

Performance

Page 24: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

Energy Dashboard – Faults

Typical AHU Layout • Provide conditioned air

• Mix Fresh and Recirculated air

• Heating Coils

• Cooling Coils

Return AirRA

Supply Air

Exhaust

Outside Air

CO

OLI

NG

PR

E H

EAT

MA T PH T SA TSA

MIX AIR DAMPER

OA T

AHU DIAGRAM

HU

MID

IFIE

R

SteamOr

HHWCHW Steam

RE

HE

AT

ING

SteamOr

HHW

• Base AHU template and 10 derived templates for specific AHU types

• Specific temperature faults for each AHU type

Page 25: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Faults

Mixed Air Fault Economizer should be

meeting set point

Pre Heat Fault Valve Closed

5F Temp Change

Cooling Fault Valve Closed

6F Temp Change

Page 26: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Implementation

Pilot - 6 months

• Develop KPI and fault calculations

• Create templates and deploy at 2 sites

9 additional sites - 4 months

• Data connections & mapping

• Leverage standard templates to drive consistency and speed of implementation

• As soon as data connected templates applied and dashboard live

Potential Future Development

• Use Event Frames (EF) to capture duration of energy faults

• Analyze zone conditions downstream of AHU’s

Page 27: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Energy Dashboard – Pilot Results • Monthly prediction model based on 2012-2016 data

• Normalized for weather and occupancy

• Expect ~8% energy savings at any given deployment site

Page 28: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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Enterprise PI deployment – Lessons Learned

• Partnership between IT & Engineering - support for interface issues

• Workshop with site representatives to gain alignment and investment in the dashboard

• SME’s drive template development and roll out

• Data alone changes nothing – need to address the issues identified

• Plan for multiple standards for measurement (metric, English, etc.)

• Limit data flow to raw data – calculations and logic applied in AF

• Local non-GMP PI system helps speed adoption and innovation

Page 29: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

RESULTS CHALLENGE SOLUTION

Eli Lilly and Company

Deliver Digital Plant concepts to manufacturing areas.

Utilize the EA agreement to enable the Digital Plant concept

Global Energy Dashboard for monitoring energy consumption

• Enterprise wide PI system with interfaces to local PI systems.

• AF used to develop common data sets, analysis, benchmarking and reporting.

• Standardized KPI’s and analytics.

• Rapid deployment to 9 sites

• ~8% energy savings after fixing

identified issues

• Improve access to data and productivity.

• Enable manufacturing sites to deliver results with speed, agility and reduced cost.

Enterprise PI and The Digital Plant

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Page 30: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

Enterprise PI and the Digital Plant

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Wilfred Mascarenhas

• Advisor – Data and Analytics, Manufacturing & Quality IT

• Eli Lilly and Company

[email protected]

Greg White

• Indianapolis Site Energy Manager

• Eli Lilly and Company

[email protected]

Page 31: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

Questions?

Please wait for

the microphone

State your

name & company

Please remember

DOWNLOAD THE MOBILE APP

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Page 32: Enterprise PI and the Digital Plant - OSIsoft · Wilfred Mascarenhas Greg White 1 . #PIWorld ©2019 OSIsoft, LLC 2 Agenda •Introductions and About Eli Lilly and Company •Digital

#PIWorld ©2019 OSIsoft, LLC

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