european handbook of dermatological treatments 2nd ed.978-3-662-07131...a. claudy, service de...
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European Handbook of Dermatological Treatments 2nd Ed.
Springer-Verlag Berlin Heidelberg GmbH
A.D. Katsambas . T.M. Lotti (Eds.)
European Handbook of Dermatological Treatments
Second Edition
With 63 Figures and 157 Tables
Springer
Professor Andreas D. Katsambas University of Athens 'A. Sygros' Hospital Department of Dermatology 5, I. Dragoumi Street 161 21 Athens Greece
Professor Torello M. Lotti University Unit Allergology Professional and Environmental Dermatology University of Florence Via Alfani 37 50 121 Florence Italy
ISBN 978-3-642-05657-4 ISBN 978-3-662-07131-1 (eBook) DOl 10.1007/978-3-662-07131-1
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© Springer-Verlag Berlin Heidelberg 2003 Originally published by Springer-Verlag Berlin Heidelberg New York in 2003 Softcover reprint of the hardcover 2nd edition 2003
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Diseases
Acne, 3 w.J. Cunliffe
Actinic keratosis, 10 F.M. Camacho-Martinez
Adamantiades-Beh<;:et's disease, 16 Ch.C. Zouboulis
Alopecia areata, 27 R. Happle
Androgenic alopecia, 35
Contents
Chronic actinic dermatitis, 97 G.M.Murphy
Cicatricial alopecia, 101 A. Tosti and B.M. Piraccini
Contact dermatitis, 106 L. Kanerva and A.!, Lauerma
Cutaneous vasculitis, 115 T.M. Lotti, C. Comacchi and I. Ghersetich
Darier's disease, 120 C. Varotti and F. Bardazzi
C. Pierard-Franchimont and G.E. Pierard Dermatitis herpetiformis, 123 C. Gooptu and F. Wojnarowska
Antiphospholipid syndrome, 42 P.G. Vlachoyiannopoulos and H.M. Moutsopoulos
Aphthous stomatitis, 48 G. Laskaris
Apocrine miliaria, 52 H.R. Bruckbauer and H.-J. Vogt
Atopic dermatitis, 54 E.J.M. Van Leent and J.D. Bos
Balanitis, 63 D. Freedman
Basal cell carcinoma, 68 D. Roseeuw, A. D. Katsambas and J.P. Hachem
Bowen's disease, 82 G. Avgerinou
Bullous pemphigoid, 86 A.G. Vareltzidis and P.G. Stavropoulos
Candidiasis, 92 D. Rigopoulos
Dermatomyositis, 126 S. Jablonska and M. Blaszczyk
Dermatophyte infections, 131 A. Tosti and B.M. Piraccini
Drug eruption, 135 J. Revuz
Drug-induced pemphigus, 139 S. Albert and M.M. Black
Drug photosensitivity, 141 P. Santoianni and E.M. Procaccini
Eccrine miliaria, 145 H.R. Bruckbauer and H.-J. Vogt
Epidermolysis bullosa, 147 G. Menchini, B. Bianchi and T.M. Lotti
Erysipelas, 157 M. Balabanova
Erythema multiforme, 159 F.M. Brandao
Erythema nodosum, 163 A. Claudy
VI Contents
Erythrasma, 167 E. Koumantaki-Mathioudaki
Erythroplasia of Queyrat, 169 B.-R. Balda
Factitial dermatitis, 171 N. Tsankov and L. Stransky
Furuncles and carbuncles, 173 D.loannides
Granuloma annulare, 177 C. Ligeron, L. Meunier and J. Meynadier
Hand dermatitis, 182 K. Thestrup-Pedersen
Herpes genitalis, 187 S. Kroon
Herpes simplex virus infection (orofacial), 193 S. Kroon
Herpes zoster, 197 S. Georgala
Hirsutism, 206 D. Rigopoulos
HIV infection and AIDS: present status of antiretroviral therapy, 211 R. Husak and C.E. Orfanos
Hyperhidrosis, 223 B. Brazzini, G. Campanile, G. Hautrnann and T.M. Lotti
Ichthyosis, 229 M. Paradisi and A. Giannetti
Impetigo, 235 S. Veraldi and R. Caputo
Kaposi's sarcoma, 239 J.D. Stratigos, A.C. Katoulis andAJ. Stratigos
Keloids and hypertrophic scars, 248 G. Hautrnann, A. Mastrolorenzo, G. Menchini and T.M. Lotti
Keratoacanthoma, 256 I. Danopoulou
Leg ulcers, 262 A.A. Ramelet
Leishmaniasis, 271 M. Onder and M. Ali Gurer
Lentigo maligna, 275 R. Dawber
Leprosy or Hansen's disease, 280 B. Flageul and I. Dubertret
Lichen planus, 289 A. Rebora
Lichen simplex chronicus, 293 M.L. Gantcheva
Lupus erythematosus, 297 B. Crich and S. Belaich
Lyme borreliosis, 304 J. Hercogova
Lymphomas (primary cutaneous), 309 W.A. van Vloten
Malignant melanoma, 321 B.-R. Balda and H. Starz
Mastocytosis, 330 A.P. Oranje and D. Van Gysel
Melasma, 336 A.D. Katsambas, A.J. Stratigos and T.M. Lotti
Mite bites, 342 G. Leigheb
Molluscum contagiosum, 344 M. V. Milinkovic and L.M. Medenica
Morphoea: circumscribed scleroderma, 352 U.-F. Haustein
Naevi (benign melanocytic), 355 N.G. Stavrianeas and A.C. Katoulis
Necrobiosis lipoidica, 368 E.M. Grosshans
Nummular eczema, 372 H.R. Bruckbauer, S. Karl and 1. Ring
Pediculosis, 377 E. Tsoureli-Nikita, G. Campanile, G. Hautrnann and 1. Hercogova
Pemphigus erythematosus, 382 S. Albert, K.E. Harman and M.M. Black
Pemphigus foliaceus, 384 S. Albert, K.E. Harman and M.M. Black
Pemphigus vegetans, 388 K.E. Harman, S. Albert and M.M. Black
Pemphigus vulgaris, 390 V. Ruocco, S. Brenner and E. Ruocco
Photoageing, 399 N.M. Craven and C.E.M. Griffiths
Pityriasis lichenoides acuta, 402 A. Andreassi and L. Andreassi
Pityriasis lichenoides chronica, 405 L. Rauch and T. Ruzicka
Pityriasis rosea, 408 H. Degreef
Pityriasis rubra pilaris, 411 lV. Cannnnarota, I. Hergocova and T.M. Lotti
Polymorphic light eruption, 416 I. Ferguson
Porphyrias,419 M. Lecha, C. Herrero and D. Ozalla
Pruritus, 427 D. Ioannides
Psoriasis, 433 B. Bonnekoh and H. Gollnick
Purpuras, 4S 1 T.M. Lotti, C. Connacchi and 1. Ghersetich
Pyoderma gangrenosum, 458 M.I. Cannilleri and I.L. Pace
Rosacea, 467 F.C. Powell
Sarcoidosis, 474 S. lablonska
Scabies, 479 A. Gorkiewicz-Petkow
Seborrhoeic dermatitis, 484 I. Faergennann
Seborrhoeic keratosis, 487 A. Picoto
Contents
Sjogren's syndrome, 490 A.G. Tzioufas and H.M. Moutsopoulos
Skin diseases from the marine environment, 494 G. Monfrecola and G. Posteraro
Solar urticaria, 498 M. leannnougin
Squamous cell carcinoma, 501 B. Giannotti and V. DeGiorgi
Subacute cutaneous lupus erythematosus, 505 M.N. Manoussakis and H.M. Moutsopoulos
Syphilis, 512 M.A. Waugh
Systemic sclerosis: scleroderma, 519 U.-F. Haustein
Tick dermatoses, 524 G. Leigheb
Tinea versicolor: pityriasis versicolor, 526 M. Ie Maitre and A. Donnpnnartin
Toxic epidermal necrolysis (Lyell's syndrome), 530 A. Minas
Urethritis: gonococcal, 535 D. Freednnan
Urethritis: non-gonococcal, 541 D. Freednnan
Urticaria, 547 F. Lawlor and A. Kobza Black
Varicella, 554 S. Georgala
VII
Vascular birthmarks: vascular malformations and haemangiomas, 561 X.-H. Gao and G. W Cherry
Vitiligo, 568 A.D. Katsannbas, T.M. Lotti and I.P. Ortonne
Warts and condylomas, 575 I.M. Mascaro and I.M. Mascaro IT
VIII
Xanthomas, 581 A.D. Tosca and J.e. Katsantonis
Methods
Acne scar treatment, 589 L. Rusciani
Biopsy, 593 E. Haneke
Chemical peeling, 599 1. Ghersetich, B. Brazzini and T. Lotti
Cryosurgery, 613 L. Marini
Curettage, 623 E. Haneke
Electrosurgery, 624 E. Haneke
Epiluminescence microscopy of pigmented skin lesions, 628 V. De Giorgi and P. Carli
Lasers, 640 L. Leite
Mohs' surgery, 645 A. Picoto, J.M. Labareda, R. Themido and F. Coelho
Patch testing, 649 A. Katsarou
Photo chemotherapy, 654 e. Antoniou
Photodynamic therapy, 658 A.D. Tosca and M.P. Stefanidou
Sclerotherapy, 664 E. Del Bianco, G. Muscarella and P. Cappugi
Skin augmentation (fillings), 669 L. Rusciani and S. Petraglia
Skin resurfacing with the carbon dioxide laser, 677 B.e. Gee and N.P.J. Walker
UVB phototherapy, 683 e. Antoniou
Contents
Drugs
Antibacterial agents, 687 H. Giamarellou and M. Souli
Antifungal drugs, 700 R.J. Hay
Antihistamines, 711 A.D. Katsambas, A.J. Stratigos and T.M. Lotti
Antiviral drugs, 716 E. Tsoureli-Nikita, G. Hautmann, G. Campanile, A.D. Katsambas and T.M. Lotti
Bleaching agents, 721 W. Westerhof and M.D. Njoo
Corticosteroids: topical, 731 J.G. Camarasa and A. Gimenez-Arnau
Glucocorticoids: systemic, 739 J.G. Camarasa and A. Gimenez-Arnau
Insect repellents, 747 S. Motta and M. Monti
Psychoactive agents, 753 G. Hautrnann and E. Panconesi
Retinoids, 769 J.H. Saurat
Scabicides and pediculicides, 775 A. Gorkiewicz-Petkow
Skin tests, 780 D. Kalogeromitros
Sunscreens, 784 S. Albert and J.L.M. Hawk
Topical anaesthetics, 790 F.B. de Waard-van der Spek and A.P. Oranje
Topical preparations and vehicles, 794 M. Monti and S. Motta
Subject index, 803
list of Contributors
s. Albert, Assistant Professor, Department of Dermatology, Kasturba Medical College, Manipal,
India
A. Andreassi, Istituto di Scienze Dermatologiche, Univ. Deg/i Studi - Policlinico Le Scotte, Viale
Bracci, 53100 Siena, Italy
L. Andreassi, Professor of Dermatology, Direttore Istituto di Scienze Dermatologiche, Univ. Degli Studi
- Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy
C. Antoniou, Associate Professor in Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
G. Avgerinou, Department of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
M. Balabanova, Department of Dermatology, Alexander's Medical University Hospital, 1, Saint G.
Sofiski St, Sofia BG-1431, Bulgaria
B.-R. Balda, Department of Dermatology &
Allergology, Zentralklinikum Augsburg, Stenglinstra~e 2, D-86156 Augsburg, Germany
P. Bardazzi, Department of Dermatology, Faculty of Medicine, University of Bologna, Via Massarenti 1,40138 Bologna, Italy
S. Belaich, Department of Dermatology, Bichat H6pital, Assistance Publique H6pitaux de Paris, 46 rue Henri Huchard, 75018 Paris, France
B. Bianchi, Istituto di Scienze Dermatologiche, Univ. Degli Studi - Policlinico Le Scotte, Viale
Bracci, 53100 Siena, Italy
M.M. Black, St. John's Institute of Dermatology,
Basement, Block 7, St Thomas' Hospital, Lambeth
Palace Road, London, SE1 7EH, U.K.
B. Bonnekoh, Department of Dermatology and
Venereology, Otto-von-Guericke-University, Leipziger Str. 44, D-39120 Magdeburg, Germany
J.D. Bos, Department of Dermatology, Academic Medical Centre, University of Amsterdam, PO Box 22700, Meibergdreef9, 1100 DE Amsterdam, The Netherlands
P.M. Brandao, Department of Dermatology,
Hospital Garcia de Orta, Av. Torrado Silva, 2800 Almada, Portugal
B. Brazzini, Dipartimento di Scienze Derm, Universita degli studi di Firenze, Via Deg/i Alfani 37,1-50121 Firenze, Italy
S. Brenner, Department of Dermatology, TelAvivSourasky Medical Centre, Tel Aviv, Israel
H.R. Bruckbauer, Dermatologist and
Allergologist, Marktplatz 7B, D-85375, Neufahrn, Germany
P.M. Camacho-Martinez, Universidad
de Sevilla, Departamento de Dermatologia, Avda. Republica Argentina 22, 5 D, Sevilla, Spain
J.G. Camarasa (deceased), Departmentof Dermatology, Hospital del Mar. IMIM, Universittat Autonoma de Barcelona, Passeig Maritim 25-29, 08003 Barcelona, Spain
M.J. Camilleri, Mayo Clinic, Rochester, MN,
USA
N. Cammarota, Istituto di Scienze Dermatologiche, Univ. Degli Studio di Siena -Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy
G. Campanile, Dipartimento di Scienze Derm,
Universita degli studi di Firenze, Via Degli Alfani
37,1-50121 Firenze, Italy
P. Cappugi, DepartmentofDermatological Science, University of Florence, Via degli Alfani 37,50121
Florence, Italy
R. Caputo, Institute of Dermatological Sciences, IRCCS, University of Milan, Via Pace 9, 1-20122 Milan, Italy
x List of Contributors
P. Carli, Dipartimento di Scienze Derm, Universita
deg/i studi di Firenze, Via Deg/i Alfani 37, 1-50121
Firenze, Italy
G.W. Cherry, Oxford Wound Healing
Institute, Department of Dermatology,
Churchill Hospital, Old Road, Headington,
Oxford, OX3 7LJ, U.K.
A. Claudy, Service de Dermatologie, Hopital
Un ivers ita ire, Hopital Edouard Herriot, Place
d'Arsanval, F-69437 Lyon Cedex 03, France
F. Coelho, Superiori Technician Pharmacy, Centro
de Dermatologia Medico-Cirurgica, ARS de Lisboa e
Vale do Tejo, I, Rua Jose Estevao 135, 1150 Lisboa,
Portugal
C. Comacchi, Dipartimento di Scienze Derm,
Universita degli studi di Firenze, Via Degli Alfani
37,1-50121 Firenze, Italy
N.M. Craven, Section of Dermatology, University
of Manchester, "Hope Hospital", Manchester, M6
8HD, U.K.
B. Crickx, Department of Dermatology, Bichat
Hopital, Assistance Publique Hopitaux de Paris, 46
rue Henri Huchard, 75018 Paris, France
W.]. Cunliffe, Skin Research Centre, The General
Infirmary at Leeds, Great George St, Leeds, LS1
3EX, U.K.
I. Danopoulou, Department of Dermatology,
University of Athens, "A Sygros Hospital", 5, I
Dragoumi St, Kesariani 16121, Athens, Greece
R. Dawber, Department of Dermatology,
Churchill Hospital, Old Road, Headington, Oxford,
OX3 7LJ, U.K.
H. Degreef, Universitaire Ziekenhuizen, Leuven
Dermatologie, UZ st. Rafael, Kapucijnenvuer 33, B-
3000 Leuven, Belgium
V. De Giorgi, Department of Dermatology,
Universita degli studi di Firenze, Via Degli Alfani
37,1-50121 Firenze, Italy
F.B. de Waard-van der Spek, Department of
Dermato-Venereology, University Hospital
Rotterdam - Dijkzigt/Sophia, Molewaterplein 60,
3015 GJ Rotterdam, The Netherlands
E. Del Bianco, Department of Dermatological
Science, University of Florence, Via degli Alfani 37,
50 121 Florence, Italy
A. Dompmartin, Department of
Dermatology, Center Hospitalier Universitaire
Caen, Avenue Georges Clemenceau, 14033
Caen Cedex, France
L. Dubertret, Department of Dermatology, Hopital
Saint-Louis, 1 Avenue Claude Vellefaux, 75475,
Paris Cedex 10, France
]. Faergemann, Associate Professor, Department
of Dermatology, Sahlgrenska University Hospital, S-
41345 Gothenburg, Sweden
]. Ferguson, Consultant Dermatologist,
Photobiology Unit, University Department of
Dermatology, Ninewells Hospital and Medical
School, Dundee, DD1 9SY, U.K.
B. Flageul, Department of Dermatology, Hopital
Saint-Louis, 1 Avenue Claude Vellefaux, 75475,
Paris Cedex 10, France
D. Freedman, Department of Medicine, University
College, Dublin, and St James' Hospital, Dublin,
Ireland
M.L. Gantcheva, Department of Dermatology,
Alexander's Medical University Hospital, 1, SaintG.
Sofiski St, Sofia BG-1431, Bulgaria
X.-H. Gao, Department of Dermatology , No.1
Hospital of China Medical University, Shenyang,
China 110001
B.C. Gee, Department of Dermatology, Queen's
Medical Centre, Nottinghan, NG72UH, U.K.
S. Georgala, Department of Dermatology,
University of Athens, "A Sygros Hospital",
5, I Dragoumi St, Kesariani 16121, Athens, Greece
I. Ghersetich, Department of Dermatology,
Universita deg/i studi di Firenze, Via Degli Alfani
37,1-50121 Firenze, Italy
H. Giamarellou, Professor ofInternal
Medicine, Infectious Diseases Specialist, Fourth
Department of Internal Medicine, Sismanoglion
General Hospital, 15126 Maroussi, Attikis,
Athens, Greece
A. Giannetti, Department of Dermatology,
University of Modena, 71 Del Pozzo str. 41100,
Modena, Italy
B. Giannotti, Dipartimento di Scienze Derm,
Universita deg/i studi di Firenze, Via Deg/i Alfani
37,1-50121 Firenze, Italy
List of Contributors XI
A. Gimenez-Arnau, Department of
Dennatology, Hospital del Mar. IMIM,
Universitdad Autonoma de Barcelona,
Passeig Maritim 25-29, 08003 Barcelona, Spain
H. Gollnick, Department of Dermatology
and Venereology, Otto-von-Guericke
University, Leipziger Str. 44, D-39120
Magdeburg, Germany
C. Gooptu, ICRF Cancer Medicine Research
Unit, St. James' University Hospital, Beckett
Street, Leeds, LS9 7TF, U.K.
A. G6rkiewicz-Petkow, Department of
Dermatology, Warsaw School of Medicine,
Koszykowa 82A, 02-008 Warsaw, Poland
C.E.M. Griffiths, Section of Dennatology,
University of Manchester, "Hope Hospital",
Manchester, M68HD, U.K.
E.M. Grosshans, Head of the
Dermatological Clinic, Faculte de Medecine,
1, Place de l'hOpital, F-67091 Strasbourg
Cedex, France
M. Ali Gurer, DepartmentofDennatology, 11 kat,
Gazi University School of Medicine, 06510 Besevler,
Ankara, Turkey
J.P. Hachem, Akademisch Ziekenhuis
Vrije Universiteit Brussel, Department of
Dennatology, 101, Laarbeeklaan, B-1090
Brussels, Belgium
E. Haneke, Professor of Dennatology, Inst.
Dennatol Klinikk BunCFs, Lokkeasveien 3, 1337
Sandvika, Norway
R. Happle, Department of Dennatology,
Philipp University of Mar burg,
Deutschhausstraf!,e 9, D-35033 Marburg,
Gennany
K.E. Harman, st. John's Institute of
Dermatology, Basement, Block 7, St
Thomas' Hospital, Lambeth Palace Road,
London, SE1 7EH, U.K.
U.-F. Haustein, DepartmentofDennatology,
University of Leipzig, Stephanstraf!,e 11, 04103
Leipzig, Germany
G. Hautmann, Specialist in Dennatology
and Venereology, Dipartimento di Scienze
Derm, Universita deg/i studi di Firenze,
Via Degli Alfani 37, I-50121 Firenze, Italy
].L.M. Hawk, Department of Environmental
Dermatology, Guy's, King's and Thomas' School of
Medicine, St John's Institute of Dermatology, St
Thomas' Hospital, Lambeth Palace Road, London,
SE1 7EH, U.K.
R.J. Hay, Faculty of Medicine and Health Sciences,
Queen's University Belfast, Whitla Medical
Building, 97 Lisbum Road, Belfast, BT9 7BL, U.K.
J. Hercogova, Department of Dennatology and
Venereology, Charles University 2nd Medical School,
Motol University Hospital, V uvalu 84, 150 06
Prague 5, Czech Republic
C. Herrero, Servei de Dennatologia, Hospital
Clinic, Facultat de Medicina, Universidad de
Barcelona, c/ Villarroe117017, E-08036 Barcelona,
Spain
R. Husak, Klinik und Poliklinik fur
Dennatologie, Universitatsklinikum Benjamin
Franklin der FU Berlin, Fabeckstr. 60-62, 14195
Berlin, Gennany
D. Ioannides, Assistant Professor ofDennatology,
Department of Dennatology and Venereology,
Aristotle University Medical School, 3 PP Gennanou
Street, 54622 Salonika, Greece
S. J ablonska, Department of Dermatology,
Warsaw School of Medicine, Koszykowa 82A,
02-008 Warsaw, Poland
M. Jeanmougin, PoliC/inique de Dennatology,
Hospital St Louis, 1 Avenue Claude Vellefaux,
75475 Paris, Cedex 10, France
D. Kalogeromitros, Departmentof
Dennatology, University of Athens, "A Sygros
Hospital", 5, I Dragoumi St, Kesariani 16121,
Athens, Greece
L. Kanerva, Finnish Institute of Occupational
Health, Topeliuksenkatu 41 aA, FIN-00250
Helsinki, Finland
S. Karl, Dermatologist and Allergologist Marktplatz
7B, D-85375 Neufahm, Gennany
A.C. Katoulis, Department ofDennatology
and Venereology, University of Athens, "A Sygros
Hospital", 5, I Dragoumi St, Kesariani 16121,
Athens, Greece
A.D. Katsambas, University of Athens, 'A. Sygros'
Hospital, Department of Dermatology, 5, l.
Dragoumi Street, 16121 Athens, Greece
XII List of Contributors
J.C. Katsantonis, Department of Dermatology, Faculty of Medicine , University of Crete, Heraklion 71110, Crete, Greece
A. Katsarou, Department of Dermatology, University of Athens, "A Sygros Hospital", S, I Dragoumi St, Kesariani 16121, Athens, Greece
A. Kobza Black, St John's Institute of Dermatology, Lambeth Palace Road, London, SE1 7EH, U.K.
E. Koumantaki-Mathioudaki, Department of Dermatology and Venereology, University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
S. Kroon, Department of Dermatology and Venereology, Heise Stavanger, SiR, University of Bergen, Pb 8100,4068 Stavanger, Norway
J .M. Labareda, Centro de Dermatologia MedicoCirurgica, ARS de Lisboa e Vale do Te;o, I, Rua Jose Estevao 135, 1150 Lisboa, Portugal
G. Laskaris, Head, Oral Medicine Clinic, Department of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
A.I. Lauerma, Skin and Allergy Hospital Helsinki, University Central Hospital, Meilahdentie 2, 00250 Helsinki, Finland
F. Lawlor, Newham Dermatology Unit, St Andrew's Hospital, London, E3 3NT, U.K., and St John's Institute of Dermatology, St Thomas' Hospital, London, SE17 EH, U.K.
M. Lecha, Servei de Dermatologia, Hospital Clinic, Facultat de Medicina, Universidad de Barcelona, c/ Villarroe117017, E-08036 Barcelona, Spain
M. Ie Maitre, 1 Avenue de 6 Juin, F-14000 Caen, France
G. Leigheb, Dermatology Clinic, Via Pansa 4, 1-28100 Novara, Italy
L. Leite, Calcada da Nuda 82-1, Lisboa, Portugal
C. Ligeron, Service de Dermatologie, Centre Hospitalier Caremeau, 30900 Nimes, France
T.M. Lotti, Dipartimento di Scienze Dermatologiche, Universita degli Studi di Firenze, Via Degli Alfani 37,1-50121 Firenze, Italy
M.N. Manoussakis, Departmentof Pathophysiology, School of Medicine, National University of Athens, 75 Mikras Asias St, 11527 Athens, Greece
L. Marini, SDC Studio Dermo Chirurgico, Via Pio Riego Gambini 35,34138 Trieste, Italy
J .M. Mascaro, Departmento de Dermatologia, Hospital Clinico, Universidad de Barcelona, Casanova, 143,08036, Barcelona, Spain
J.M. Mascaro Jr, Departmento de Dermatologia, Hospital Clinico, Universidad de Barcelona, Casanova, 143, 08036, Barcelona, Spain
A. Mastrolorenzo, Dipartimento di Scienze Derm, Universita degli studi di Firenze, Via Degli Alfani 37, 1-50121 Firenze, Italy
L.M. Medenica, Department of Dermatology and Venereology Clinical Centre of Serbia, School of Medicine, University of Belgrade, 2 Pasterova St, 11000 Belgrade, Yugoslavia
G. Menchini, Istituto di Scienze Dermatologiche, Univ. Degli Studi - Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy
L. Meunier, Centrum Gruene Gentechnik, Staatliche Lehr- und Forschungsanstait, Breitenweg 71, 67435, Neustadt an der Weinstrasse, Germany
J. Meynadier, Service de Dermatologie, Hopital st. Eloi, 2 Avenue Berlin Sans, F-34295 Montpellier Cedex 5, France
M.V. Milinkovic, Department of Dermatology and Venereology, Clinical Centre of Serbia, School of Medicine, University of Belgrade, 2
Pasterova St, 11000 Belgrade, Yugoslavia, and Harvard Skin Disease Research Center, Brigham and Women's Hospital, Department of Dermatology, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
A. Minas, Department of Dermatology, Aristotle University Medical School, 124 Delphon Street, 54643 Salonika, Greece
G. Monfrecola, DepartmentofPatologia Sistemica Section of Dermatology, Universim di Napoli 'Federico II', Via S. Pansini 5,80131 Napoli, Italy
List of Contributors XIII
M. Monti, Istituto Clinico Humanitas,
Unit of Dennatology, University of Milan,
Via Manzani 56, 1-20089 Rozzano, Milan, Italy
S. Motta, Istituto Clinico Humanitas,
Unit of Dermatology, University of Milan,
Via Manzani 56, 1-20089 Rozzano, Milan, Italy
H.M. Moutsopoulos, Departmentof
Pathophysiology, School of Medicine, National
University of Athens, 75 Mikras Asias St, 11527
Athens, Greece
G.M. Murphy, National Photobiology Unit,
Beaumont Hospital, Dublin 9, Ireland
G. Muscarella, Department ofDennatological
Science, University of Florence, Via degli Alfani 37,
50121 Florence, Italy
M.D. Njoo, DepartmentofDennatology, Academic
Medical Centre, University of Amsterdam, PO Box
22700, Meibergdreef9, 1100 DE Amsterdam, The
Netherlands
M. Onder, Department of Dennatology, Gazi
University School of Medicine, 06510 Besevler,
Ankara, Turkey
A.P. Oranje, Department of Dennatology,
University Hospital Rotterdam - Dijkzigt/Sophia,
Molewaterplein 60, 3015 GJ Rotterdam, The
Netherlands
C.E. Orfanos, Klinik und Poliklinik fur
Dermatologie, Universitatsklinikum Benjamin
Franklin der FU Berlin, Fabeckstr. 60-62, 14195
Berlin, Gennany
]. -P. Ortonne, Department of Dennatology,
University of Nice, Hopital de l'Archet 2, 151, route
St-Antoine de Ginestiere, F-06202 Nice, Cedex 3,
France
D. Ozalla, Servei de Dennatologia, Hospital Clinic,
Facultat de Medicina, Universidad de Barcelona, c/ Villarroell7017, E-08036 Barcelona, Spain
J.L. Pace, 59 Marquis Scicluna St, Naxxar NXR 03,
Malta
E. Panconesi, Specialist in Dennatology and
Venereology, Dipartimento di Dermatologia,
Universita degli studi di Firenze, Via Degli Alfani
37,1-50121 Firenze, Italy
M. Paradisi, "San Gallicano" Institute, Rome,
Italy
S. Petraglia, Catholic University, Dept of
Dennatology, L.go A. Gemelli 8, 00168 Rome,
Italy
A. Picoto, Centro de Dennatologia Medico
Cirurgica, ARS de Lisboa e Vale do Tejo, I, Rua Jose
Estevao 135, 1150 Lisboa, Portugal
G .E. Pierard, Department of Dennatopathology,
CHV Sart Tilman, B-4000 Liege, Belgium
C. Pierard-Franchimont, Department of
Dermatopathology, CHV Sart Tilman, B-4000
Liege, Belgium
B.M. Piraccini, Department of Dennatology,
University of Bologna, Via Massarenti 1, 40138
Bologna, Italy
G. Posteraro, Department ofPatologia Sistemica
Section of Dennatology, Universita di Napoli
'Federico II', Via Pansini 5,80131 Napoli, Italy
EC. Powell, Regional Centre of Dermatology,
Mater Miseraecordia Hospital, Eccles Street, Dublin-
7, Ireland
E.M. Procaccini, Department of Dennatology,
Universita "Federico II" de Napoli, Via S. Pansini 5,
80131 Napoli, Italy
A.A. Ramelet, 2 Place Benjamin-Constant, CH-
1003 Lausanne, Switzerland
L. Rauch, Department of Dennatology-Hautklinik,
Moorenstrasse 5, 40225 Dusseldorf, Gennany
A. Rebora, Department ofDennatology, University
of Genoa, Genoa, Italy
]. Revuz, Service de Dennatologie, Henri Mondor
Hospital, 51, Ave du Marechal de Lattre de Tassigny,
F-9401O Creteil Cedex, France
D. Rigopoulos, Department of Dennatology,
University of Athens, "A Sygros Hospital", 5, I
Dragoumi St, Kesariani 16121, Athens, Greece
]. Ring, Department of Dermatology and
Allergy Biederstein, Technical University
Munich, Biedersteinerstraf5e 29, D-80802
Munich, Gennany
D. Roseeuw, Akademisch Ziekenhuis Vrije
Universiteit Brussel, Department of Dennatology,
101, Laarbeeklaan, B-1090 Brussels, Belgium
E. Ruocco, Department of Dermatology,
School of Medicine and Surgery, Second University of
Naples, Via S. Pansini 5,80131 Napoli, Italy
XIV List of Contributors
V. Ruocco, Head, Department of Dermatology, School of Medicine & Surgery, Second University of Naples, Via S. Pansini 5,80131 Napoli, Italy
1. Rusciani, Department of Dermatology, Catholic University of Sacred Heart, Largo A. Gemelli 8, 00168 Rome, Italy
T. Ruzicka, Department of DermatologyHautklinik, Moorenstraf!,e 5, 40225 Diisseldorf,
Germany
P. Santoianni, Department of Dermatology, Universita "Federico II" de Napoli, Via S. Pansini 5, 80131 Napoli, Italy
J .H. Saurat, Clinique & Policlinique de Dermatologie, Hopital Universitaire, CH-1211 Geneva 14, Switzerland
M. Souli, Fourth Department of Internal Medicine, Athens University School of Medicine, Sismanoglio General Hospital, 1 Sismanogliou Str., 15126
Maroussi, Attikis, Athens, Greece
H. Starz, Department of Dermatology and Allergology, Klinikum Augsburg, Stenglinstraf!,e 2, D-86156 Augsburg, Germany
N.G. Stavrianeas, Department of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
P.G. Stavropoulos, Second Department of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
M.P. Stefanidou, Department of Dermatology, Heraklion University General Hospital, Heraklion, Crete, Greece
1. Stransky, Unit of Contact Dermatitis and Occupational Diseases of the Skin, Medical
University, Alexander's Medical University Hospital, 1, Saintg. Sofiski St, Sofia BG-1431, Bulgaria
A.J. Stratigos, Department of Dermatology,
University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
J.D. Stratigos, Department of Dermatology, University of Athens, "A Sygros Hospital", 5, I
Dragoumi St, Kesariani 16121, Athens, Greece
R. Themido, Centro de Dermatologia Medico
CiTUrgica, ARS de Lisboa e Vale do Tejo, I, Rua lose Estevao 135, 1150 Lisboa, Portugal
K. Thestrup-Pedersen, University of Aarhus, Department of Dermatology, Marselisborg Hospital, DK-8000 Aarhus C, Denmark
A.D. Tosca, Department of Dermatology, Heraklion
University General Hospital of Crete, Heraklion, 71110 Crete, Greece
A. Tosti, Department of Dermatology, University of Bologna, Via Massarenti 1, 40138 Bologna, Italy
N. Tsankov, Department of Dermatology, Alexander's Medical University Hospital, 1, Saint g. Sofiski St, Sofia BG-1431, Bulgaria
E. Tsoureli-Nikita, Istituto di Scienze Dermatologiche, Univ. Degli Studi - Policlinico Le
Scotte, Viale Bracci, 53100 Siena, Italy
A.G. Tzioufas, Department of Pathophysiology, School of Medicine, National University of Athens, 75 Mikras Asias St, 11527 Athens, Greece
E.J.M. Van Leent, Department of Dermatology, Academic Medical Centre, University of Amsterdam, PO Box 22700, Meibergdreef9, 1100 DE Amsterdam, The Netherlands
W.A. van Vloten, Department of Dermatology, University Medical Centre Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
A.E. Vareltzidis, Department of Dermatology, University of Athens, "A Sygros Hospital", 5, I Dragoumi St, Kesariani 16121, Athens, Greece
C. Varotti, Department of Dermatology, University of Bologna, Via Massarenti 1, 40138 Bologna, Italy
S. Veraldi, Institute of Dermatological Sciences, fRCCS, University of Milan, Via Pace 9, f-20122
Milan, Italy
P.G. Vlachoyiannopoulos, Departmentof Pathophysiology, School of Medicine, National
University of Athens, 75 Mikras Asias St, 11527 Athens, Greece
H.-J. Vogt, Department of Dermatology and Allergy Biederstein, Technical University
Munich, Biedersteinerstraf!,e 29, D-80802
Munich, Germany
N.P.J. Walker, Department of Dermatology,
Churchill Hospital, Old Road, Headington, Oxford, OX3 7Ll, U.K.
List of Contributors xv
M.A. Waugh, Genito Urinary Medicine
Department, The General Infirmary at Leeds, Great
George St, Leeds, LS1 3EX, U.K.
W. Westerhof, Netherlands Institute for
Pigmentary Disorders/AMC IWO gebouw,
Meibergdreef 35, 1105 AZ Amsterdam, The
Netherlands
F. Wojnarowska, Department of Dermatology,
Churchill Hospital, Old Road, Headington, Oxford,
OX3 7LT, U.K.
Ch.C. Zouboulis, Klinik und Poliklinik fUr
Dermatologie, Universitiitsklinikum Benjamin
Franklin der FU Berlin, Fabeckstr. 60-62, 14195
Berlin, Germany
Preface
This handbook presents the combined work of many prominent dermatologists from throughout Europe, based on their profound knowledge and clinical experience in various fields of dermatology. The purpose of this manual is to provide an easy to use guide that describes not only the many dermatological diseases diagnosed today, but also the analogous drugs and methods of treatment available. Hence, as indicated in the title, dermatologists and non-dermatologists will find its contents to be most useful and concise.
The manual is divided into three main sections: Diseases, Methods, and Drugs. The first part of the handbook defines each disease with brief information on its etiology and pathophysiology. This is followed by a short account of diagnostic procedures and an extensive discussion of treatment and therapy. The authors have not only presented classic and modern approaches to treatment, but also provided their personal recommendations on the bases of their expertise. The middle
section describes up-to-date methods and the possible use of therapeutic equipment for diagnosis and treatment. The final section provides an alternative approach, indicating where medication and drugs could be an appropriate choice in the treatment of dermatological diseases.
This second edition of the European Handbook of Dermatological Treatments has been minimally revised and retains the exact form of the previous publication.
The response received from the initial publication was enthusiastic and the book was widely accepted. It has been a great pleasure to provide this handbook to fellow colleagues and new dermatologists in the continuing endeavour to treat dermatological and cutaneous diseases.
We wish to express our gratitude to all the distinguished colleagues who contributed towards this venture.
Andreas Katsambas, Torello Lotti 2003