excellence at the school of pharmacy · 2020-02-20 · • plein certificate in geriatric pharmacy....

EXCELLENCE AT THE SCHOOL OF PHARMACY 2013

Table of Contents1 Welcome from Dean Baillie 2 Our Excellence: A Summary 3 Grants 4 Our Impact 10 Our Loyal Supporters 14 Selected Publications

LeadershipThomas Baillie, Dean

Peggy Odegard, Chair, Department of Pharmacy

Allan Rettie, Chair, Department of Medicinal Chemistry

Kenneth Thummel, Chair, Department of Pharmaceutics

Nanci Murphy, Associate Dean, Academic & Student Programs

Sean Sullivan, Associate Dean, Research & New Initiatives

Stanley Weber, Associate Dean, Professional Pharmacy Education

Claire Forster, Assistant Dean, Advancement & Corporate Relations

Christene James, Director, Finance & Administration

Programs, Facilities and UnitsAnalytical Biopharmacy Core

Community & Ambulatory Pharmacy Practice Residency Program

DNA Sequencing & Gene Analysis Center

Geriatric Pharmacy Program

Institute for Innovative Pharmacy Practice

L.D. & Jim Bracken Pharmacy Learning Center

Mass Spectrometry Center

Metabolism & Transport Drug Interaction Database

Northwest-Alaska Pharmacogenomics Research Network

Pharmaceutical Outcomes Research & Policy Program

Pharmacokinetics Lab

UW Obstetric-Fetal Pharmacology Research Unit

UW Pharmacy Cares Consulting Pharmacy

UW Research Affiliate Program on Transporters

Front Cover: Sliding doors at the entrance of the Magnuson Health Sciences Center Rotunda. Photo by Team Photogenic.

UW SCHOOL OF PHARMACY

We seek to provide them with an excellent education and countless opportunities for development; then we watch them go on to successful and meaningful careers — as pharmacists, scientists, professors, public health officials, policymakers and much more.

We also take pride in the ways our students and faculty are responding to pressing needs in public health and health care. We are made up of an impassioned community of people working to improve the health and well-being of individuals and communities. This 2013 issue of “Excellence at the School of Pharmacy” is a testament to that.

Within these pages, you will find a snapshot of the work our students, faculty, alumni and volunteers are doing regionally and globally to improve health, health care and outcomes. On , for example, you will note the impressive amount of research funds our faculty members secured — for studies focused on areas including vaccine creation, drug interactions, obstetric-fetal pharmacology and comparative effectiveness research. Starting on Page 4, you can read about some students and faculty members who are having an impact — from a professor known for inspiring students in the classroom and the clinic to a graduate student helping surgeons in Tanzania improve surgical outcomes. On Page 10, we pay tribute to our generous donors and volunteers — without whom, we could not make the mark that we do.

You may notice that much of the work highlighted in this report is focused on finding safer, more-effective medicines and treatments. Part of our core mission is to help ensure the safe, rational and cost-effective use of medicines and medical products in human populations.

What a worthwhile goal this is. Better treatments lead to improved health outcomes. And that can open doors to a world of better health.

Thank you for your interest in and support of our School.

Sincerely,

Thomas A. Baillie, PhD, DSc

DEAN, UW SCHOOL OF PHARMACY

WELCOME

At the UW School of Pharmacy, we

pride ourselves on the role we play in

opening doors for our students’ growth.

[ 2013 Excellence Report 1 ]

Our ExcEllEncE: A SummAry

11% STATE FUNDS

3% OTHER3% RESEARCH

COST RECOVERY

3% GIFTS

51% GRANTS & CONTRACTS

1% ENDOWMENT RETURN

2% SALES & SERVICES

13% OUTPATIENTPHARMACY

13% TUITION

By the Numbers

Our Stellar Programs

DEGREES:

•DoctorofPharmacy(PharmD)

•MasterofScience(MS)inBiomedicalRegulatoryAffairs,PharmaceuticalOutcomesResearch&PolicyProgram(PORPP)

•DoctorofPhilosophy(PhD)inMedicinalChemistry,Pharmaceutics,PORPP

•Concurrent:PharmD/PhD,PharmD/MS,PharmD/MasterofClinicalHealthServices

CERTIFICATES:

•BiomedicalRegulatoryAffairs

•ClinicalTrials

•ComparativeEffectivenessResearch

•HealthEconomics&OutcomesResearch

•PleinCertificateinGeriatricPharmacy

Revenue

*Figuresarefromfiscalyear2012(July1,2011-June30,2012)

3The UW’s 2012 global ranking in clinical medicine and pharmacy by the Center for World-Class Universities 4Number of American Association

for the Advancement of Science faculty fellows in our School

10 Our U.S. News & World Report 2012 ranking among schools of pharmacy

42Full-time equivalent faculty members

82Percentage of PharmD graduates in 2012 who stayed in Washington to practice pharmacy

500+Clinical and affiliate faculty members

466Currently enrolled students (364 PharmD, 59 PhD, 43 MS)

$17.5 million*Overall research funding secured

$34.6 million*Revenue

[ 2 sop.washington.edu ]

GrAntS

Abbreviated Project Title Funding AgencyDirect Cost Fiscal Year 2012 PI

Multiyear Total, if Applicable*

Pharm Optimization NIH $501,734 Anderson $2,594,290

PGP Mechs NIH $219,000 Atkins $880,685

LSDF BioE Center WA Life Sciences Discovery Fund $258,028 Atkins and Catalano

$980,778

Various Projects Fred Hutchinson Cancer Research Center (FHCRC) $33,469 Blough

HIV Env Trimer Spikes NIH $160,232 Catalano $273,750

Lambda Capsid National Science Foundation $194,382 Catalano $717,700

Viral DNA NIH (U Cal San Diego subcontract) $189,706 Catalano $348,161

Andrews F32 Fellowship NIH $53,942 Catalano $152,874

CERTN EDM Paper AcademyHealth/AHRQ - ARRA $7,500 Devine

Fellowship Allergan Inc. $75,046 Devine $134,939

Comparative Effec Rsch PhRMA Foundation $125,000 Garrison $250,000

Pfizer Fellowship 3 Pfizer Inc. $115,736 Garrison $223,521

Bedalov Biomarkers Sub NIH (FHCRC subcontract) $8,123 Goodlett

Artemisinin Compounds WA Life Sciences Discovery Fund $87,883 Goodlett $258,527

g2AMPK NIH $34,102 Goodlett $183,787

Morrison P30 (Core B) NIH $175,846 Goodlett $688,567

NWRCE (RCE CORE D Y9) NIH $103,855 Goodlett $519,773

Anticholinergic Med Group Health Research Institute $18,807 Gray $93,491

UW-Obstetric Fetal Pharmacology RU NIH NICHD $515,550 Hebert $3,250,000

pH-CD4-DDS NIH $586,292 Ho $2,226,630

MIP HIV NIH NIAID (U Utah subcontract) $204,590 Ho $1,061,619

Oral HIV vaccines NIH $277,789 Hu $2,032,927

HIV-1 Drug Resistance NIH NIAID (U Pittsburgh subcontract) $181,563 Hu $393,620

Pinter HIVRAD Prj 3 NIH PHRI (U of Med & Dentistry of NJ subcontract) $389,050 Hu $2,307,180

Hu-IPS st-HIV-1 Institut Pasteur of Shanghai-Chinese Acad Sciences $143,768 Hu

Modulation of receptor NIH NIAID (U Mass Medical School subcontract) $518,457 Hu $2,054,979

Clade C Core NIH (Dana-Farber Cancer Institute subcontract) $120,652 Hu $1,069,773

Core A – NHP Model NIAID (FHCRC subcontract) $587,986 Hu $3,030,628

Unmasking HIV Epitopes Bill & Melinda Gates Foundation $5,175,945 Hu $6,269,066

Xenobiotics NIH $186,219 Isoherranen $933,664

Flu Fusion NIH $190,000 Lee $950,000

Structure of HIV Env NIH CFAR (U Alabama Birmingham subcontract) $150,000 Lee $207,789

Crucell Assays Crucell Holland B.V. $6,800 Lee

Guttman F32 Fellowship NIH $49,214 Lee $101,404

Pediatric CYP2D6 NIH (Children's Mercy Hosp, Kansas City subcontract) $160,066 Lin $524,287

Pharmacogenetics NIH $250,521 McCune $501,543

Staff assignment FHCRC $24,416 McCune

UNCF/Merck – Hardy United Negro College Fund $90,000 Nelson

Plankton NSF (Georgia Inst of Tech subcontract) $31,495 Nunn $94,511

HSR and D Project – VA US Dept of Veterans Affairs $11,700 Odegard

Drug Metabolism Training Grant NIH $566,295 Rettie $2,828,769

Drug Interactions NIH $937,696 Rettie $4,672,107

Bastyr/UW Oncomycology NIH $18,159 Shen $46,159

PCOR K12 NIH/AHRQ $417,820 Sullivan $1,160,883

Variations in Health Merck and Co. Inc. $148,521 Sullivan

Pharmacogenetics NIH/NIGMS $2,307,604 Thummel $8,053,777

Role of CYP2J2 NIH $222,750 Totah $1,118,250

UW Research Affil Prg Transporters AstraZeneca LP/Genentech Inc./Merck $240,000 Unadkat

CANCERGEN Y2 NIH (FHCRC subcontract) – ARRA $351,881 Veenstra

GHC SA 2 NIH/Group Health $29,196 Veenstra

TOTAL: $17,454,386 TOTAL: $51,609,016

*Multiyeartotalsonsubcontractgrantsareestimatedbasedoncurrentyearfunding.


Gail Anderson, PhD, Professor

Larry Bauer, PharmD, Professor

Douglas Black, PharmD, Associate Professor

Josh Carlson, PhD, Assistant Professor

Colleen Catalano, PharmD, Clinical Assistant Professor

Lingtak-Neander Chan, PharmD, Associate Professor

Jennifer Danielson, MBA, PharmD, Clinical Assistant Professor

Karan Dawson, PhD, Clinical Associate Professor

Emily Beth Devine, PharmD, PhD, Associate Professor

Donald Downing, BS, I2P2 Endowed Clinical Professor

Allan Ellsworth, PharmD, Professor

Jean Feagin, PhD, Senior Lecturer

Jackie Gardner, PhD, Professor Emeritus

Louis Garrison, Jr., PhD, Professor

Amber Glass, MPH, Clinical Assistant Professor

Shelly Gray, PharmD, Professor

Dana Hammer, PhD, Senior Lecturer

Ryan Hansen, PharmD, PhD, Acting Assistant Professor

Philip Hansten, PharmD, Professor Emeritus

Thomas Hazlet, PharmD, DrPH, Associate Professor

Mary Hebert, PharmD, Professor

John Horn, PharmD, Professor

Michaelene Kedzierski, BS, Clinical Professor

Susan Lakey, PharmD, MPH, Clinical Assistant Professor

Jeannine McCune, PharmD, Professor

Skye McKennon, PharmD, Clinical Assistant Professor

Nanci Murphy, PharmD, Lecturer

Shanna O’Connor, PharmD, Acting Assistant Professor, Kelley-Ross Faculty Fellow

Peggy Odegard, PharmD, Bridge Endowed Professor and Department Chair

Teresa O’Sullivan, PharmD, Lecturer

Joy Plein, PhD, Professor Emeritus

Danny Shen, PhD, Professor

Shabir Somani, MBA, Associate Professor

Sean Sullivan, PhD, Professor, Stergachis Endowed PORPP Director

David Veenstra, PharmD, PhD, Professor

Stanley Weber, PharmD, Associate Professor

Cathy Yeung, PharmD, PhD, Acting Assistant Professor

*All faculty listings throughout this report reflect our faculty members during fiscal year 2012.

Doug Black’s ability to connect with students has made him well-liked among PharmD students since he first joined

the Department of Pharmacy in 1989. Black, who teaches classes in pharmacotherapeutics and infectious disease, is known for tailoring his lectures to meet each group’s needs and for his enthusiasm for his subject matter.

Like many of his faculty colleagues, Black also serves as a preceptor to future pharmacists. As part of the UW Medical Center’s Division of Infectious Diseases health care team, he mentors several pharmacy residents and PharmD students on rotation each year. Patients in this unit are facing diseases ranging from HIV/AIDS to rare infections that can have devastating symptoms. That so many students and residents finish Black’s rotation with a newfound interest in working in infectious disease units is a testament to his clinical skills.

One lesson he teaches his mentees is that it is essential to consider the specific needs and issues of each patient when determining the right combination of medications.

There is no “one size fits all” in pharmacotherapy. Just as, for Black, there is no “one size fits all” in

teaching. His personal approach is one of the reasons he has received the UW’s highest

teaching honor — the Distinguished Teaching Award. And it’s just one of the reasons why the PharmD pro-gram is known for innovation in education.

Driven by a Love of Teaching

Doug Black, left, talks with PharmD students. Black has been a popular Department of Pharmacy professor and preceptor for more than 20 years.

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Our Impact


WhilehewasaPharmDstudent,ZsoltHeppplacednationallyintwoacademiccompetitions.In2009,he

was on a student team that took grand prize in the National CommunityPharmacistsAssociationPruitt-SchutteBusinessPlanCompetition.In2010,HeppandhisteamplacedsecondintheAcademyofManagedCarePharmacy’sAnnualPharmacy&Therapeutics(P&T)Competition.

Ashepreparedforthesecontests,Heppgainedagreaterunderstanding of the complexity of the pharmacy profession and thehealthcaresystem.HisP&Tresearchinparticularpiquedhisinterest.P&Tfocusesonformularymanagement—theprocessof approving drugs for safety and cost effectiveness and making recommendationsforuseandpreparation.Heppsawhowmuchthis information shapes health policy, and he decided to become involved in influencing patient outcomes at this level.

AftergraduatinginJune2012,hetookontworoles—asapharmacist at Walgreens and an Allergan Fellow in our School’s PharmaceuticalOutcomesResearch&PolicyProgram(PORPP).AtWalgreens,Heppismanagingpatients’needsonanindi-viduallevel.AsaPORPPfellow,heisevaluatinghealth-relatedoutcomes for medications on a larger scale. At present, he is examining resource-use patterns in migraine patients using prophylactic medications.

WhenheenrolledattheUW,Heppdidn’tknowhe’dbecomeinterested in so many different aspects of patient care. But that’s what the School of Pharmacy is about — creating diverse opportunitiesandlettingstudentslikeHeppfindtheirpassionand thrive.

PharmDcandidateLauraHart,’14,spentthreeyearsvolunteering at a long-term care center pharmacy prior to

pharmacy school. While there, she saw firsthand the important role pharmacists play in improving the health of older adults. As someone close to her own grandparents, she loved working with this population of people.

Today, the third-generation UW pharmacy student contributes widely to the School’s efforts to advocate for older populations. She is president of the UW student chapter of the American SocietyofConsultantPharmacists(ASCP)—ageriatricpharmacyorganization.HerworkwithASCPhasincludedorganizingandparticipating in medication reviews, fall-prevention programs and osteoporosis-prevention workshops.

HartispursuingthePleinCertificateinGeriatricPharmacy,andsheisaPleinFellowinGeriatrics.Asafellow,sherecentlystartedaresearchprojectwithUWPharmacyCares,theSchool’sconsultingpharmacyprogram.SheandfacultymembersKaranDawsonandSusanLakeyareworkingwithtwoEraLivingRetirementCommunitysitestolookatmedication-relatedproblemsandtoassess resident, family and staff perceptions of consulting pharmacy services.

HartisoneofmanyUWPharmDstudentswhoarehighlyinvolvedin outreach, research and leadership activities. What’s more, herfellowstudentsareengagedinprojectssupportingmanypopulationsandpublichealthissues.Inthepharmacyfield,afterall,therearecountlesswaystomakeadifference.ForHart,thismeans a future career serving the complex health needs of a generation close to her heart.

ONE DEGREE, MANY OPTIONS FOR THE FUTURE

MEETING THE NEEDS OF OUR NATION’S SENIORS

For Zsolt Hepp, his PharmD degree helped him discover a newfound interest in evaluating health-related outcomes for medications.

Laura Hart, seen here at an osteoporosis-screening event, looks forward to a career helping improve the health of older generations.


Carol Collins, MD, Clinical Associate Professor

Rodney Ho, PhD, Professor

Shiu-Lok Hu, PhD, Milo Gibaldi Endowed Professor

Nina Isoherranen, PhD, Associate Professor

Edward Kelly, PhD, Research Assistant Professor

Suzanne Lee, PharmD, Clinical Associate Professor

Rene Levy, PhD, Professor Emeritus

Yvonne Lin, PhD, Assistant Professor

Qincheng Mao, PhD, Associate Professor

Bhagwat Prasad, PhD, Acting Instructor

Isabelle Ragueneau-Majlessi, MD, Clinical Associate Professor

Danny Shen, PhD, Professor

Kenneth Thummel, PhD, Professor and Milo Gibaldi Endowed Department Chair

Jashvant Unadkat, PhD, Professor

Joanne Wang, PhD, Associate Professor

Each year, 1.7 million people in the United States sustain a traumatic brain injury. Although numerous clinical studies have

tried using single drug treatments for people with brain injuries, the results have been overwhelmingly disappointing. Gail Anderson, professor of pharmacy and adjunct professor of pharmaceutics and neurosurgery, is in search of a more successful treatment method.

Her current research, funded by a $2.5 million NIH grant, seeks to identify combinations of medications that could prevent long-term health issues for brain-injured patients. Some of these long-term issues include epilepsy and residual physical, cognitive, emotional and behavioral impairment.

Anderson knows that daily life can change significantly for patients diagnosed with epilepsy. With this in mind, she has been a patient advocate, community volunteer and professional advisory board member of the Epilepsy Foundation Northwest for more than 20 years. She also precepts pharmacy students at the UW Regional

Epilepsy Center at Harborview Medical Center — helping them provide the best care possible to patients

in the clinic and at the bedside.

A UW alumna (BS in pharmacy, MS in pharmacy practice, PhD in pharmaceutics), Anderson received the School’s 2010 Distinguished Alumna Award for her research, teaching and community involvement. It is one of many career honors she has received. While Anderson appreciates such accolades, what she especially appreciates is knowing that her research could one day help people seeking hope after surviving a traumatic injury.

WORKING TO HELP PEOPLE WITH BRAIN INJURIES

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Gail Anderson is a nationally recognized expert on anticonvulsant medications and their use in epilepsy.

OUR IMPACT


http://sop.washington.edu

PharmaceuticalOutcomesResearch&PolicyProgram(PORPP)graduatestudentAmyCizikspentlast

summerinDarEsSalaam,Tanzaniapilotingamobilephone application that enters surgical follow-up data. CiziksoughttodeterminewhethersurgeonsattheMuhimbiliOrthopaedicInstitutecouldmoreeasilyenterpatients’ post-surgery progress with a smart phone data and photo application than with traditional data entry methods.

AndyStergachis,PORPPadjunctprofessorandUWpro-fessorofglobalhealth,guidedCizikinherproposalforfundingandservedasherprojectmentor.ThefundingcamefromtheUWThomasFrancis,Jr.,GlobalHealthFellowshipProgram.Inaddition,CizikcollaboratedwithSIGNFractureCareInternational,ahumanitarianorga-nization that provides orthopaedic treatment to people in developing countries.

WhatCizikultimatelydiscoveredduringhertimeinTanzania was that few people who receive fracture care attheInstituteactuallyreturnforfollow-up.Theydon’t

have the means to get back to the clinic to meet with a physician.Cizik,therefore,willcontinueworkingwithSIGNtoassessbettermethodsforpatientfollow-up.Ultimately,shehopestohelpSIGNtrackpatients’outcomesandtohelpSIGN’spatientsworldwidegetthe appropriate follow-up care in their recovery process.

CizikenrolledinPORPPbecauseofitsfocusonimproving health care decisions for patients and decision makers. With a background in public health and orthopaedics research, she wanted to research the clinical and economic effects of orthopaedic devices in patient populations.

Inthefuture,shehopestocollaboratewithorthopaedicsurgeons to study cost and outcomes of orthopaedic interventions or to help surgeons in other countries conduct similar research. No matter how this takes shape, she will have an international network of supportasanalumnaofPORPP.

ASSESSING SURGICAL OUTCOMES IN TANZANIA

PORPP graduate student Amy Cizik is observing the orthopaedic surgeons, residents and an anesthesiologist as they prep a patient for knee surgery.

A pile of past-patient follow-up radiographs at the Muhimbili Orthopaedic Institute in Tanzania tower over Cizik.

Cizik, who went to Tanzania as a UW Thomas Francis, Jr., Global Health Fellow, enrolled in PORPP because of its focus on improving health care decisions for patients and decision makers.


Morethanadecadeago,ProfessorofPharmaceuticsJashvantUnadkatbeganstudy-ing how drug transporters affect the disposition, efficacy and toxicity of drugs used

totreatdiseasessuchashepatitisCandAIDS.Transportersaremembraneproteinsthathelpthebodyabsorb,distribute,metabolizeandexcretedrugs.Giventhecomplexityoftransporters, the variability of human genetics, and the sheer volume of transporters in the human body, the collective scientific knowledge about transporters has long contained many gaps. Unadkat seeks to change that.

In2012,helaunchedtheUWResearchAffiliatesProgramonTransporters(UWRAPT),apartnershipbetweentheSchoolofPharmacyandAstraZeneca,GenentechandMerck.TheUWCenterforCommercializationandOfficeofSponsoredProgramshelpedmakethis

undertaking possible.

ThroughUWRAPT,researchersfromthefourinstitutionsarecollaboratingonnonproprietary research to enhance knowledge about the types and amount of transporters expressed in human tissues. This kind of academic-industry collaboration on nonexclusive research is rare. And it has exciting implications for other potential future partnerships that our School could launch.

UnadkatandUWRAPTleadscientistBhagwatPrasadhopeUWRAPT’sresearchwilladvance the collective knowledge about how the body processes medicines. They wanttohelpscientistsbetterpredictthefateofnewdrugsearlyindevelopment.Inturn, this will help health care providers prevent drug interactions and understand how genetics affect the way individuals process medications.

A COLLABORATIVE EFFORT TO IMPROVE DRUG SAFETY

Jashvant Unadkat, left, and Bhagwat Prasad are currently in discussions with additional research companies interested in joining UWRAPT.

“This kind of academic-industry collaboration on nonexclusive research is rare. And it has exciting implications for other potential future partnerships that our School could launch.”

OUR IMPACT



William Atkins, PhD, Professor

Thomas Baillie, PhD, DSc, Bloedel Endowed Professor, School of Pharmacy Dean

Carlos Enrique Catalano, PharmD, PhD, Professor

Gary Elmer, PhD, Professor Emeritus

David Goodlett, PhD, Professor

Kent Kunze, PhD, Associate Professor

Kelly Lee, PhD, Assistant Professor

Wendel Nelson, PhD, Professor

Allan Rettie, PhD, Professor and Department Chair

Rheem Totah, PhD, Associate Professor

In loving memory, 2011: Sidney Nelson, PhD, Professor and Dean Emeritus

A Continued Legacy of Innovation

Our School is continually finding ways to innovate education, research and outreach. In fact, we’re leading the way in these endeavors. The following are some of the new programs we have launched in the past five years alone:

•AnalyticalBiopharmacyCore,inpartnership with the UW Department of Bioengineering

•BiomedicalRegulatoryAffairsMasterofScience

•CertificateinHealthEconomicsandOutcomes Research

•GraduateCertificateinComparativeEffectiveness Research

•Northwest-AlaskaPharmacogenomicsResearch Network, in partnership with several tribes, foundations and universities

•PharmacologicalSciencesSummerDiversity Research Program

•UWGlobalMedicines,inpartnershipwiththe UW Department of Global Health

•UWPharmacyCaresConsultingPharmacy

•UWResearchAffiliateProgramonTransporters, in partnership with AstraZeneca, Genentech and Merck

ProfessorofMedicinalChemistryCarlosEnriqueCatalanohasdevoted his career to understanding how viruses work —

specifically how they put themselves together in an infected cell. CurrentstudiesinhislabfocusonHIVandonbacteriophagelambda, a virus that looks and behaves like the herpes viruses. By enhancing scientific knowledge about the formation of these viruses, Catalano’sresearchcouldmakeiteasierforresearcherstodesignspecific antiviral drugs and vaccines.

Catalanoisalsodevotedtomentoringyoungpeoplefromdiversebackgrounds. As faculty adviser to the award-winning UW chapter oftheSocietyfortheAdvancementofChicanosandNativeAmericansinScience,Catalanoworkswithanenthusiasticgroupofundergraduate and graduate students engaged in scientific research. These students themselves have developed outreach programs for Latino and Native American high schoolers.

Like many other faculty members, he also offers undergraduates the chancetoworkinhislab.StudentscometotheCatalanoLabfromprograms such as the Amgen Scholars Program, the UW School of Pharmacy’sPharmacologicalSciencesSummerDiversityProgram,andtheUW’sPost-BaccalaureateResearchEducationProgram(PREP),fundedbyNIH.CatalanohelpedcreatetheDiversityProgramandheservesasco-PIforPREP.

Catalanoenjoystryingtoinstillaloveofscienceinyoungpeople.Who knows? One day, one of those young people might work on thecureforavirusstudiedintheCatalanoLab.

OPENING DOORS FOR YOUNG RESEARCHERS AND SCIENTISTS

Carlos Catalano is known throughout the scientific community for his wide-ranging efforts to encourage young people to take an interest in the sciences.

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CORPORATIONS AND FOUNDATIONS $25,000+Allergan Inc.

Amgen

Bayer AG

ERA Living

Bill & Melinda Gates Foundation

Genentech

Kelley-Ross Pharmacy

McKesson Corporation

Merck & Co. Inc.

Pfizer Inc.

PhRMA Foundation

Public Health Research Institute

United Negro College Fund

Newly Created School of Pharmacy Funds 2012

•AndjelkovicConnellEndowedStudent Support Fund

•DougBlackEndowedFund

•HigashiFamilyPORPPEndowedStudent Fellowship Fund

•Kelley-RossFacultyFellowship

•DennisLamMemorialFund

•StergachisFamilyEndowedPORPP Directorship

continued on page 11

OUR LOYAL SUPPORTERS We are so grateful to our volunteers and donors for their time, energy and financial

contributions. Their support is critical to our efforts to educate first-rate pharmacists, developscientificleadersandservethecommunity.Inthesepages,wepresentthenamesofthecompaniesandindividualsthatmadegiftstoourSchoolattheDean’sClubLevelandabove,andthosethatgavedonationstostudenteventsinfiscalyear2012(July1,2011toJune30,2012).We also present the names of our advisory board members from fiscal year 2012.

While these are our most prominent supporters, there are countless more individuals and com-panies working behind the scenes to support our students, faculty and School in so many ways. We are indebted to every single one of you.

A proud tradition continues: Our School is once again ranked No. 1 among all UW schools in terms of percentage of alumni giving!

Rite Aid Corporation

Safeway District Management

The Bartell Drug Company

WA State Pharmacy Foundation

Walter & Hazel Hinman Fdtn.

LESS THAN $2,500Abbott Fund

Albertson’s Inc.

Aqua Verde Cafe Paddle Club

Asia Gifts & Aquarium

Beal’s Compounding Pharmacy

Bergman Luggage Company Inc.

Bioscrip Pharmacy

Bob Johnson’s Pharmacy

The Boeing Company

Bonck Family Trust

Bristol-Myers Squibb Foundation

Career Staff Rx

Central WA Hospital Pharmacy

Chinook Pharmacy Inc.

Columbia Valley Com. Health

Com. Health Ctr. of Snohomish

Community Pharmacy Scotland

Dimitriou’s Jazz Alley

Dow AgroSciences LLC

Evergreen Hospital Med Ctr.

Evergreen Senior Health Specialist

Experience Music Project

Fdtn. for Managed Care Pharmacy

Fred Meyer

Garage

Garfield Medical Square Pharmacy

Genelex

Greater Everett Community Fdtn.

Green Mountain Coffee Roasters

Harrison Medical Center

HealthPoint

Island Hospital Anacortes

$10,000 - $24,999 GlaxoSmithKline

The Kroger Co.

Walgreens

$2,500 - $9,999AcademyHealth

American Pharmacists Association

Bi-Mart

CVS Caremark

Eli Lilly & Co. Foundation

GE Foundation

Genentech Inc.

John Wiley & Sons Inc.

Kelley-Ross Pharmacy Inc.

Lincoln Pharmacy

Morgan Stanley/SmithBarney

Our Donors


Ivar’s Inc.

JC’s True Care Pharmacy Inc.

KCS Enterprises LLC

Kiehl’s

Kirk’s Pharmacy

Krusty Dimino’s Corp.

Kwong Wah Hospital

Main Street Gyros

Market Optical

Massage Envy

Medical Center Pharmacy

Microsoft Corporation

Monroe Correctional Complex

Monsoon Restaurant

MultiCare Health System

Myrtle Warneke Education Fdtn.

NACDS Foundation

NCPA Foundation

Nicholson’s Sumner Pharmacy

Nintendo of America Inc.

Northshore Scholarship Fdtn.

Odessa Drug

Pfizer Pharmaceuticals

Pharm Data

Pharmaca Integrative Pharmacy

Pharmaceutical Systems Inc.

Pharmacist Access Corp.

Pharmacists Mutual Insurance Co.

Pike Brewing Company

Propac Pharmacy

Providence Health & Services

Providence St. Peter Hospital

Regence Employee Giving

Ron’s Apothecary

Rxtra Care Inc.

Safeway Inc.

Samaritan Pacific Com. Hsptl.

Seattle Aquarium

Seattle Sounders LLC

Stevens Pass

Strategic North

Sullivan University

Sun Ya Seafood Restaurant

SuperValu Inc.

Swedish Medical Center

Target Stores

The Everett Clinic

The Medicine Shoppe

The Ram Restaurant

The Seattle Foundation

The Seattle Mariners

Thermo Fisher Scientific

Tim’s Pharmacy & Gift Shop

Time Warner Inc.

Tripler Army Medical Center

U.S. FDA

UBC Health Care Analytics

Underground Tour

United States Navy

United Way Treasure Valley

University Book Store

Valley Medical Center

Valmont Park Homeowners Assoc.

WA State Board of Pharmacy

Walmart Stores Inc.

Waters Corporation

Waterways Cruises

Wells Fargo Foundation

WHO Global Programme

Woodland Park Zoo

Zoeyogurt

ZymoGenetics

INDIVIDUALS $5,000+

Thomas & Kathleen Baillie

Geraldine Brady

Herb Bridge

Lara & Jacob Connell

Florence Gibaldi

Mitchell & Mandy Higashi

Mark & Pamela Holzemer

Joan Nelson

Joy Plein

Lance & Sheila Pohl

Danny & Barbara Shen

Sean & Catrena Sullivan

Caryl Trager

David Veenstra

Bing-Bing Yang

PRESIDENT’S CLUB

Evelyn Arrigoni

Janet & Douglas Black

Timothy Carlson & Luann Aki

Weichao & Sandy Chen

Michael & Margaret Faulkner

Jackie Gardner & Gary Elmer

Louis & Frances Garrison, Jr.

Remodeled Bracken Center Unveiled

In fall quarter 2012, the newly remodeled L.D. & Jim Bracken Pharmacy Learning Center, our PharmD student learning lab, opened! It features upgrades to the center’s integrated learning areas, which include a sterile products preparation room, patient-counseling areas and a retail space. In addition, the beautiful new lab now has advanced QS1 software and more advanced pharmacy learning technology.

This remodel was made possible by the Bracken Family, CVS Pharmacy, Kelley-Ross Pharmacy, McKesson Inc. and Walgreens.

continued on page 12

The Bracken Center includes several high-tech teaching resources. Pictured here is Associate Professor of Medicinal Chemistry Kent Kunze with PharmD students.

John Bracken, left, and sister Laura Clough (Bracken), children of Jim and Sharon Bracken, cut the ribbon at a celebration in October.

(Less than $2,500 cont’d)


Kevin Hiroo

Rodney Ho & Lily Hwang-Ho

Richard & Janet Hunter

Al & Carolynn James

Bradley Kerr & Caroline Lee

Kevin Koch & Kathy Maloney

Stephen & Kathy Kushner

Mark Holodniy & RoseAnn Kushner

Craig & Sally Kvam

Michael & Tammy Lafferty

Virginia Leland

Donavon & Nicole McConn

David Nelson

Patrick & Missy O’Donnell

Richard & Jane Ramsey

Brian Seiki

Kenneth & Peggy Thummel

Chris & Gail Whitley

Larry & Margaret Wienkers

Donald & Arda Williams

Bradley Wong

Mingshe Zhu

DEAN’S CLUBKimberly Adkison

Arnold & Gail Anderson

Richard & Teresa Austin

Ronald & Kathleen Beil

Cynthia Bishop

Kari & Adam Brothers

Cindy Bueler

Sonia Carlson & Bobby Kishore

Judith & Barry Christensen

Bonnie & Walter Davison

James & Karan Dawson

Beth Devine

Leslie Dickmann

Donald & Donna Dockter

Donald & Anne Downing

Gregory Edmiston & Debra Leith

Jon Eisenberg & Soraya Madani

William & Sharon Fassett

Andrew & Claire Forster

Vivian & Roel Ganiron

Mark & Sissi Grillo

Shuko Hara

Thomas Hazlet

Kirk Henne

Nina Hill

Vivian & Jeffrey Hiroo

Peng Hsiao

Shiu-Lok Hu

Lorraine Humm

Paul & Mary Kuehn

Joseph & Yue Lam

Sze Lau

Rene & Beloria Levy

Richard & Margaret Marshall

Anne Mock

Michael Mohutsky

Kellie Nakamura

David & Peggy Odegard

Larry & Ellen Oliver

Marla & Patrick Osinski

Guy Padbury

Ruth & Patrick Parker

Kevin Pasquali

Gregory & Gloria Pollock

C. Rene & David Porubek

From left: Trang Le, ’93, UW Clinical Instructor of Pharmacy Elyse Tung, ’08, and School of Pharmacy Student Services Adviser Cher Espina.

From left: Brian Choi and Daiana Huyen of Walgreens, and Collin Conway, ’05, of Group Health. Huyen and Conway are members of the School of Pharmacy’s Pharmacy Practice Board. “Because of the support of people like you, I

was able to achieve my dream and attend this university. I hope my experience at the UW will lead to opportunities that will help me contribute to a wide variety of populations in my career.” PAIGEMATHEW,’16,SCHOLARSHIPRECIPIENT

OUR LOYAL SUPPORTERS CONT’D

(President’s Club cont’d)


James & Patricia Ramseth

Shelby & Steve Reed

James & Diann Robbers

Henry Sasame

Harry Schnepf II & Cameron Fosterling

Donald & Sharon Shaw

Shabir & Salma Somani

Allan Rettie & Shannon Stewart

SuAnn Stone

Bettie Tomchalk

Clyde & Sherrelle Walker

Joann Warren

Kelli Watari

YOUNG ALUMNI DEAN’S CLUBJonathan & Christina Campbell

Aaron Chin

Stephanie Decker & George Guenther

Kelly & Kyle Hackney

Amy Little

Catherine Ulep

Dimay Wang

Every effort has been made to represent the names of our donors at the Dean’s Club level and above in fiscal year 2012 accurately. We apologize for any errors or omissions. For a full list of donors to the School, visit sop.washington.edu and view the Fall 2012 alumni magazine, Dawg Scripts.

At left is UW Professor of Epidemiology and Global Health and Adjunct Professor of Pharmacy Andy Stergachis. To his right are Stergachis Family Endowed PORPP Director and Professor Sean Sullivan, School of Pharmacy Distinguished Alumnus Award Recipient Ryan Hansen, PharmD, ’03, PhD, ’12, and Washington State Pharmacy Foundation President John Oftebro.

Our Board Members

CORPORATE ADVISORY BOARD (Organizations with Member Representatives)

Abbott Laboratories

Allergan Inc.

Amgen Inc.

Astellas U.S. Inc.

AstraZeneca

Bayer Healthcare

Bend Research Inc.

Biogen Idec

Boehringer Ingelheim Pharmaceuticals

Bristol-Myers Squibb

Celgene Corporation

Covance

dwm Consulting LLC

Eli Lilly & Co.

En Vivo

GE Healthcare

Genentech Inc.

GlaxoSmithKline

Hoffman-La Roche

Ironwood Pharmaceuticals

Janssen Alzheimer Immunotherapy

Johnson & Johnson

Lilly Research Labs

McKesson Corp.

Medtronic

Merck

Mitsubishi Tanabe

Novartis

Omeros Corp.

Pfizer Inc.

Premera Blue Cross

Sanofi-Aventis

SAR Safety Assessment

Seattle Genetics

Takeda Pharmaceuticals International

Theravance Inc.

Vertex Pharmaceuticals

PHARMACY PRACTICE ADVISORY BOARD

Carol Carnahan, ‘80, Bartell Drug Co.

Collin Conway, ’05, Group Health

Daiana Huyen, Walgreens

Al Linggi, ’71, McKesson Corp.

Ryan Oftebro, ’03, Kelley-Ross Pharmacy

Chuck Paulsen, Quality Food Centers

Jeff Rochon, ’99, WSPA

Steve Singer, ’81, Bellegrove Pharmacy

Shabir Somani, UW Medicine

Susan Teil Boyer, ‘72, American Society of Health-System Pharmacists

David West, ‘79, Swedish Hospital

Jennifer Wilson-Norton, ‘93, The Evergreen Clinic

PHARMACY ALUMNI ASSOCIATION BOARD OF DIRECTORS

President: Jennifer Glasco, ’09, The Polyclinic

Immediate Past-President: Jenny Arnold, ’06, Washington State Pharmacy Association (WSPA)

Past Presidents: Suzanne Lee, ’88, Northwest Hospital, and Ben Michaels, ’97, St. Francis Hospital

Member at Large: Judi Mar-Burbidge, ’82, ’00, Seattle Veterans Administration

Katterman Chair: Don Downing, ’75, UW School of Pharmacy

WSPA Liaison: Jeff Rochon, ’99, WSPA



SELECTED PUBLICATIONS This list includes a sampling of recent books, book chapters, articles and reviews in professional

journals.Itexcludesletters,technicalreportsandconferencepresentations.SchoolofPharmacyauthors(includingcurrentandrecentfacultymembers,affiliateandadjunctfacultymembers,researchers,postdoctoralfellows,andstudents)areinbold.

Anderson GD, Farin FM, Bammler TK, Beyer RP, Swan A, Wilkerson HW, Kantor ED, Hoane MR. The effect of progesterone dosing on gene expression following traumatic brain injury. J Neurotrauma 2011.

Anderson GD, Saneto RP. Current oral and non-oral routes of antiepileptic drug delivery. Adv Drug Deliv Rev 2012.

Babigumira JB, Stergachis A, Veenstra DL, Gardner JS, Ngonzi J, Mukasa-Kivunike P, Garrison LP. Potential cost-effectiveness of universal access to modern contra-ceptives in Uganda. PLoS ONE 2012.

Babu KN, Kunze KL, Nelson WL. Metabolism of Diltiazem. A Short Efficient Synthesis of N,NDidesmethyldiltiazem—An Important Product of N-Demethylation. Synthesis 2011.

Baillie TA. Metabolic Activation and Associated Drug Toxicity (chapter). Handbook of Metabolic Pathways, Vol. 1. Chichester, UK: John Wiley & Sons; In Press. (Eds. Lee PW, Aizawa H, Gan LL, Prakash C, Zhong D).

Bauer LA. Applied Clinical Pharmacokinetics (web). New York, NY: McGraw-Hill; 2011-2012.

Bauer LA: Clinical Pharmacokinetics and Pharmacodynamics (Chapter 8). Pharmacotherapy: A Pathophysiologic Approach, 8th ed. (web). New York, NY: McGraw-Hill Medical; 2011. (Eds. DiPiro JT, et al).

Bell GA, Kantor ED, Lampe JW, Shen DD, White E. Use of glucosamine and chondroitin in relation to mortality. Eur J Epidemiol 2012.

Boudreau DM, Yu O, Gray SL, et al. Concomitant use of cholinesterase inhibitors and anticholinergics: Prevalence and outcomes. J Am Geriatr Soc 2011.

Bray BS, Schwartz CR, Odegard PS, Hammer DP, Seybert AL. Assessment of human patient simulation-based learning. Am J Pharm Ed 2011.

Chan LN. To Hold (Enteral Feeding) or Not to Hold: That IS the Question; A Commentary and Tutorial. Practical Gastroent 2012.

Cheng MM, Ramsey SD, Devine EB, Garrison LP, Bresnahan BW, Veenstra DL. A systematic review of the evidence supporting the clinical and economic value of oncology drugs marketed in the United States. Am J Manag Care 2012.

Danielson J, Ramirez J, Krueger J, et al. The capacity ratio as a measure of solvency in experiential education. Am J Pharm Ed 2011.

Dawson, K. Tobacco cessation products section. Smoking Cessation During Pregnancy: Guidelines for Intervention, Revised Edition 2012. Olympia, WA: Washington State Department of Health; 2012. (Eds. Bailey D, et al).

Dietrich E, Brennan G, Ferguson B, Wiseman RW, O’Connor D, Hu S-L. Variable prevalence and functional diversity of the antiretroviral restriction factor TRIMCyp in Macaca fascicularis. J Virol 2011.

Downing D. Inviting the pharmacist: a model for improved reproductive care access (Editorial). Contraception 2012.

Endsley AN, Ho RJY. Design and characterization of novel peptide coated lipid nanoparticles for specific anti-HIV drug delivery to HIV host cells. AAPS J 2012.

Feagin JE, et al. The fragmented mitochondrial rRNAs of Plasmodium falciparum. PLoS ONE 2012.

Floyd JS, Kaspera R, Marciante K, Weiss NS, Heckbert S, Lumley T, Wiggins K, Tamraz B, Kwok P, and co-senior authors Totah RA and Psaty BM. A screening case-control study of drug-drug interactions in statin users: a new adverse effect of clopidogrel. Clin Pharmacol Ther 2012.

Flum DR, Kwon S, MacLeod K, Wang B, Alfonso RC, Garrison LP, Sullivan SD. The use, safety and cost of bariatric surgery before and after Medicare’s National Coverage Decision. Annals Surgery 2011.

Foti RS, Honaker M, Nath A, Pearson JT, Buttrick B, Isoherranen N, Atkins WM. Catalytic versus inhibitory promiscuity in cytochrome P450s: implications for evolu-tion of new function. Biochem 2011.

Garrison LP, Bauch CT, Bresnahan BW, Hazlet TK, Kadiyala S, Veenstra DL. Using cost-effectiveness analysis to support research & development portfolio prioritization for product innovations in measles vaccination. J Infectious Disease 2011.

Gillard PJ, Devine EB, Varon S, Maglinte GA, Hansen RN, Sullivan SD. Mapping from disease-specific measures to health-state utility values in migraineurs. Value Health 2012.

Guttman M, Kahn M, Garcia N, Hu S-L, Lee KK. Solution Structure, Conformational Dynamics, and CD4-induced Activation in Full-length, Glycosylated, Monomeric HIV gp120. J Virol 2012.

Guttman M, Scian M, Lee KK. Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry. Anal Chem 2011.


Hansten P, Horn JR, The Top 100 Drug Interactions: A Guide to Patient Management. Freeland, WA: H&H Publications; 2012.

Harrelson JP, Stamper BD, Chapman JD, Goodlett DR, Nelson SD. Covalent Modification and Time-Dependent Inhibition of Human CYP2E1 by the Meta Isomer of Acetaminophen. Drug Metab Dispos 2012.

Hebert MF. Impact of Pregnancy on Maternal Pharmacokinetics of Medications (chapter). Clinical Pharmacology During Pregnancy. New York, NY: Academic Press; In Press. (Ed. Mattison D).

Ho HT, A Dahlin, Wang J. Expression profiling of solute carrier gene families at the blood-CSF barrier. Frontiers in Neuropharm. E-pub 2012.

Ho HT, Xia L, Wang J. Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activ-ity and sensitivity to inhibition by dilazep. Biochem Pharmacol 2012.

Ho RJ. A New Collaboration Platform for Improving Clinical Drug Development (Editorial). J Pharm Sci 2011.

Horn JR. Important Drug Interactions and Their Mechanisms (Chapter 66). Basic and Clinical Pharmacology, 12th ed. New York, NY: McGraw-Hill; 2012. (Ed. Katzung B).

Horn JR, Hansten PD. Metoclopramide and Dyskinesia. Pharm Times 2012.

Ishibe N, Carlson JJ, Ramsey SD, et al. Use of epidermal growth factor receptor mutation analysis in patients with advanced non-small-cell lung cancer to determine erlotinib use as first-line therapy. PLoS Curr 2011.

Isoherranen N, Lutz JD, Chung S, Hachad H, Levy RH, Ragueneau-Majlessi I. Importance of multi-P450 inhibition in drug-drug interac-tions: evaluation of incidence, inhibition magnitude and prediction from in vitro data. Chem Res Toxicol. E-pub 2012.

Jimenez N, Anderson GD, Shen DD, et al. Is ethnicity associated with morphine’s side effects in children? Morphine pharmacoki-netics, analgesic response and side effects in children having tonsillectomy. Pediatric Anesthesia 2012.

Kaspera R, Naraharisetti SB, Evangelista EA, Marciante KD, Psaty BM, Totah RA. Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cyto-chrome P450 reductase and cytochrome b5. Biochem Pharmacol 2011.

Kelly EJ, Yarov-Yarovoy V, Rettie AE. CYP4B1 (cytochrome P450, family 4, subfamily B, polypeptide 1). Atlas Genet Cytogenet Oncol Haematol 2012.

Kelly EJ, Nakano M, Rohatgi P, Yarov-Yarovoy V, Rettie AE. CYP4V2 and CYP4F22: Orphan P450s for orphan ocular and skin diseases. Mol Interventions 2011.

Kirby BJ, Collier AC, Kharasch ED, Dixit V, Desai P, Whittington D, Thummel KE, Unadkat JD. Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6 and 2C9 by Ritonavir or Nelfinavir. Drug Metab Dispos 2011.

Kirby BJ, Collier AC, Kharasch ED, Whittington D, Thummel KE, Unadkat JD. Complex Drug Interactions of HIV Protease Inhibitors 1: Inactivation, Induction and Inhibition of Cytochrome P450 3A by Ritonavir or Nelfinavir. Drug Metab Dispos 2011.

Lam AL, Odegard PS, Gardner JS. School of Pharmacy–based medication therapy man-agement program: Development and initial experience. J APhA 2012.

Lee KK, Pessi A, Gui L, Santoprete A, Talekar A, Moscona A, Porotto M. Capturing a fusion intermediate of influenza hemagglutinin with a cholesterol-conjugated peptide, a new antiviral strategy for influenza virus. J Biol Chem 2011.

Lin VW, Ringold S, Devine EB. Comparison of ustekinumab with other biologic agents for treatment of moderate-to-severe psoriasis: A Bayesian network meta-analysis. Arch Dermatol 2012.

Liu X, Sirotkin Y, Shen Y, Anderson G, Tsai YS, Ting YS, Goodlett DR, et al. Protein identi-fication using top-down spectra. Mol Cell Proteomics 2011.

McCune J, Sullivan SD, Clarke L, Blough DK, McDermott C, Malin J, Ramsey SD. Colony stimulating factor use and impact on febrile neutropenia among patients with newly diagnosed breast, colorectal, or non-small cell lung cancer receiving chemotherapy. Pharmacother 2012.

McCune JS, Woodahl EL, Furlong T, Storer B, Wang J, Heimfeld S, Deeg HJ, O’Donnell PV. A pilot pharmacologic biomarker study of busulfan and fludarabine in hematopoietic cell transplant recipients. Cancer Chemo Pharmacol 2012.

McDermott C, Gray SL. Cholinesterase inhibitor adjunctive therapy for cognitive impairment and depressive symptoms in older adults with depression. Ann Pharmacother 2012.

McDonald MG, Au NT, Wittkowsky AK, Rettie AE. Warfarin-amiodarone drug-drug interactions: determination of [I](u)/K(I,u) for amiodarone and its plasma metabolites. Clin Pharmacol Ther 2012.

Medina EM, Andrews BT, Nakatani E, Catalano CE. The Bacteriophage Lambda gpNu3 Scaffolding Protein is an Intrinsically Disordered and Biologically Functional Procapsid Assembly Catalyst. J Mol Biol 2011.

Medina EM, Nakatani E, Kruse S, Catalano CE. Thermodynamic Characterization of Viral Procapsid Expansion into a Functional Capsid Shell. J Mol Biol 2012.

Mornar S, Chan LN, Mistretta S, Neustadt A, Martins S, Gilliam M. Pharmacokinetics of the etonogestrel contraceptive implant in obese women. Am J Obstet Gynecol 2012.

Nelson WL. Antihistamines and Related Antiallergic and Antiulcer Agents (Chapter 32). Foye’s Principles of Medicinal Chemistry, 7th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2013. (Eds. Lemke TL, Williams DA, et al).

Ni ZL, Bikadi Z, Shuster DL, Zhao CS, Rosenberg MF, Mao Q. Identification of proline residues in or near transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity. Biochem 2011.

Ni ZL, Mao Q. ATP-Binding Cassette Efflux Transporters in Human Placenta. Curr Pharm Biotech 2011.

Nurmemmedov EM, Castelnovo M, Medina E, Catalano CE, Evilevitch A. Challenging Packaging Limits and Infectivity of Phage Lambda. J Mol Biol 2012.

Odegard PS, Tadeg H, Downing D, et al. Strengthening Pharmaceutical Care in Ethiopia Through Instructional Collaboration. Am J Pharm Ed 2011.

Park BK, Boobis A, Clarke S, Goldring CEP, Jones D, Kenna JG, Lambert C. Laverty HG, Naisbitt DJ, Nelson SD, Nicoll-Griffith DA, Obach RS, Routledge P, Smith DA, Tweedie DJ, Vermeulen N, Williams DP, Wilson ID, Baillie TA. Managing the Challenge of Chemically Reactive Metabolites in Drug Development. Nature Rev Drug Discov 2011.


Parkinson OT, Kelly EJ, Bezabih E, Whittington D, Rettie AE. Bioactivation of 4-Ipomeanol by a CYP4B enzyme in bovine lung and inhibition by HET0016. J Vet Pharmacol Ther 2011.

Peng CC, Shi W, Lutz JD, Kunze KL, Liu JO, Nelson WL, Isoherranen N. Stereospecific metabolism of itracon-azole by CYP3A4: dioxolane ring scission of azole antifungals. Drug Metab Dispos 2012.

Peron EP, Gray SL, Hanlon JT. Medication use and func-tional status decline in older adults: A narrative review. Am J Geriatr Pharmacother 2011.

Piascik P, Bouldin A, Schwarz K, Pittenger A, Medina MS, Rose R, Soltis R, Scott S, Creekmore F, Hammer D. Rewarding excellence in pharmacy teaching. Curr Pharm Teach Learn 2011.

Raccor BS, Claessens A, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA. Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo. Drug Metab Dispos 2012.

Ramsey SD, McCune JS, Blough DK, McDermott CL, Beck SA, Lopez J, Deeg HJ. Patterns of blood product use among patients with myelodysplastic syndrome. Vox Sang 2011.

Raymond E, Westley E, Blithe D, Brahmi D, Cameron S, Cleland K, Coeytaux F, Davis D, Downing D, et al. Emergency Contraceptive Pills: Medical and Service Delivery Guidelines, 3rd ed. New York, NY: International Consortium for Emergency Contraception; 2012.

Ritchie TK, Kwon H, Atkins WM. Conformational analy-sis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2. J Biol Chem 2011.

Roth JA, Carlson JJ. Prognostic Role of ERCC1 in Advanced Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis. Clin Lung Cancer 2011.

Shen DD. Toxicokinetics (Chapter 7). Casarett & Doull’s Toxicology: The Basic Science of Poisons, 8th ed. New York, NY: McGraw-Hill; in press. (Ed. Klaassen CD).

Shoben AB, Levin G, de Boer IH, Yeung C, Watnick S, Ayers E, Kestenbaum B. Variation in oral calcitriol response in patients with stages 3-4 CKD. Am J Kidney Dis 2012.

Sholukh AM, Mukhtar M, Humbert M, Essono S, Watkins JD, Vyas HK, Shanmuganathan V, Hemashettar G, Kahn M, Hu S-L, et al. Isolation of monoclonal antibodies with predetermined conformational epitope specificity. PLoS ONE 2012.

Shuster DL, Hebert MF, Mao Q. Glyburide Disposition During Pregnancy (Chapter 19). Gestational Diabetes. Rijeka, Croatia: InTech; 2011. (Ed. Radenkovic M).

Stergachis A, Hazlet TK, Boudreau DM. Pharmacoepidemiology (Chapter 9). Pharmacotherapy: A Pathophysiologic Approach, 8th ed. (web). New York, NY: McGraw-Hill Medical; 2011. (Eds. DiPiro JT, et al).

Takakusa H, Wahlin MD, Zhao C, Hanson KL, New LS, Chan EC, Nelson SD. Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib. Drug Metab Dispos 2011.

Topletz AR, Thatcher JE, Zelter A, Lutz JD, Tay S, Nelson WL, Isoherranen N. Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases. Biochem Pharmacol 2012.

Wang Z, Lin YS, Zheng XE, Senn T, Hashizume T, Scian M, Dickmann LJ, Nelson SD, Baillie TA, Hebert MF, Blough D, Davis CL, Thummel KE. An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway. Mol Pharmacol 2012.

Wang Z, Senn T, Kalhorn T, Zheng XE, Zheng S, Davis CL, Hebert MF, Lin YS, Thummel KE. Simultaneous measurement of plasma vitamin D(3) metabolites, including 4 β,25-dihydroxyvitamin D(3), using liquid chromatography-tandem mass spectrometry. Anal Biochem 2011.

Wong DF, Lam AY, Chan SK, Chan SF. Quality of life of caregivers with relatives suffering from mental illness in Hong Kong: roles of caregiver characteristics, caregiving burdens, and satisfaction with psychiatric services. Health Qual Life Outcomes 2012.

Wong E, Wang BCM, Garrison LP, Alfonso RC, Flum D, Arteburn D, Sullivan SD. Body mass index trajectories among the severely obese: results from an electronic medical records population. Obesity 2012.

Woods CM, Fernandez C, Kunze KL, Atkins WM. Allosteric activation of cytochrome P450 3A4 by α-naphthoflavone: branch point regulation revealed by isotope dilution analysis. Biochem 2012.

Xing J, Kirby BJ, Whittington D, Wan Y, Goodlett DR. Evaluation of CYPs Inhibition and Induction by Artemisinin Antimalarials in Human Liver Microsomes and Primary Human Hepatocytes. Drug Metab Dispos 2012.

Zhang X, Tolzmann CA, Melcher M, Haas BJ, Gardner MJ, Smith JD, Feagin JE. Branch point identification and sequence requirements for intron splicing in Plasmodium falciparum. Eukaryot Cell 2011.

In the past few years, our faculty members have been interviewed for stories in the Associated Press, New York Times, Huffington Post, Seattle Times and Pacific Northwest Magazine, as well as for stories on KUOW radio and KOMO4 TV, among others.

SELECTED PUBLICATIONS CONT’D


http://www.ncbi.nlm.nih.gov/pubmed/21937435




For admissions info, visit sop.washington.edu/school-of-pharmacy/degree-programs

To make a gift, visit sop.washington.edu/support•Forgeneralinquiries,[email protected]

CreditsEDITOR AND WRITER: MelindaYoung

DESIGNER: KarinMellskog,UWCreativeCommunications

PROOFREADER: Sharon Ernst, We Know Words

CONTRIBUTORS: ThomasBaillie,JessicaBrase,RayBrooks,SarahEgan,ClaireForster, JulieHill,ChristeneJames,JeanineKanov,DimaLong,MauraMurphy,TracieZeigler

PHOTOGRAPHERS: MattHagenPhotography,KarenHeathPhotography,MichaelNaiman of Team Photogenic

ADDITIONAL PHOTO CREDITS: iStock,ThinkStock,UWMarketing

SpecialthankstoUWCreativeCommunications,LithoCraft,andthemanyfaculty,staff,studentsand work study students who contributed photos, information and general feedback to this report.

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medical products in human populations. What a worthwhile goal this is. Better treatments lead to improved

health outcomes. And that can open doors to a world of better health.” DEANTHOMASBAILLIE


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