facts of erm
TRANSCRIPT
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Presented by :
ANTOINETTE RHEMA LOUIS (III – BDS)
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HERTWIG’S EPITHELIAL ROOT SHEATH
FORMATION
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SCHEMATIC DIAGRAM :
F :
EPITHELIAL
CELL RESTS
OF MALASSEZ
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EPITHELIAL CELL RESTS OF MALASSEZ
LOCATION
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FUNCTIONS :
Cementoblast
differentiation
Periodontal
homeostasis and
regeneration
Protection against
root resorption
Maintains periodontal
space
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KNOWN FACT :
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INFLAMMATORY
CYTOKINES ARE
RESPONSIBLE
FOR RADICULAR
CYST
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AIM OF MY PRESENTATION :
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ON NET SEARCH :
SOME INTERESTING
FACTS ON EPITHELIAL
CELL RESTS OF
MALASSEZ :
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PERIODONTAL
HOMEOSTASIS –
REGENERATION
AND REPAIR
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CEMENTAL REPAIR
Noggins
Bone morphogenicprotein.
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EXPRESSION OF CK8, OPG, OPN GENES
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STEM CELL
SUBPOPULATION
Epithelial –
mesenchymal
interaction
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ON ELECTRON
MICROSCOPY :
IN RESTING STATE :
IN ACTIVE STATE :
In resting state :
In active state :
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EXPRESSION
OF MARKERS :
HSP
VEGF
OPN
Mechanical stress
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ALTERED Gli2
EXPRESSION
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PTCH -1
GENE
MUTATION
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XRCC – 1
POLY
- MORPHISM
predicts
Ameloblastom
a
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N - METHYL N -
NITROSOUREA
INDUCES
AMELOBLASTOMA
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BUT THE QUESTION
IS YET
UNANSWERED…????
??
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