facultad de veterinaria 2020/21 year - uco...devlin tm (2015) bioquímica. libro de texto con...
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2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
COURSE DETAILS
BIOQUÍMICATitle (of the course):Code: 102210Degree/Master: Year: 1GRADO DE CIENCIA Y TECNOLOGÍA DE LOS ALIMENTOSName of the module to which it belongs: FORMACIÓN BÁSICA COMÚNField: BIOQUÍMICACharacter: BASICA Duration: SECOND TERMECTS Credits: 6.0 Classroom hours: 60Face-to-face classroom percentage: 40.0% Study hours: 90Online platform: http://moodle.uco.es/m2021/
LECTURER INFORMATION
Name: LÓPEZ LOZANO, FRANCISCO ANTONIO (Coordinador)Department: BIOQUÍMICA Y BIOLOGÍA MOLECULARArea: BIOQUÍMICA Y BIOLOGÍA MOLECULAROffice location: Edificio Severo Ochoa, planta 1, ala Este, C6E130E-Mail: [email protected] Phone: 957211075URL web: http://www.uco.es/grupos/adapromet/Home.html
Name: GARCÍA FERNÁNDEZ, JOSÉ MANUELDepartment: BIOQUÍMICA Y BIOLOGÍA MOLECULARArea: BIOQUÍMICA Y BIOLOGÍA MOLECULAROffice location: Edificio Severo Ochoa, planta 1, ala Este, C6E120E-Mail: [email protected] Phone: 957211075URL web: http://www.uco.es/grupos/adapromet/Home.html
Name: GÓMEZ BAENA, GUADALUPEDepartment: BIOQUÍMICA Y BIOLOGÍA MOLECULARArea: BIOQUÍMICA Y BIOLOGÍA MOLECULAROffice location: Edificio Severo Ochoa, planta 1, ala Este, C6E110E-Mail: [email protected] Phone: 957211075URL web: http://www.uco.es/grupos/adapromet/Home.html
Name: MUÑOZ MARÍN, MARÍA DEL CARMENDepartment: BIOQUÍMICA Y BIOLOGÍA MOLECULARArea: BIOQUÍMICA Y BIOLOGÍA MOLECULAROffice location: Edificio Severo Ochoa, planta 1, ala Este, C6E130E-Mail: [email protected] Phone: 957211075URL web: http://www.uco.es/grupos/adapromet/Home.html
PREREQUISITES AND RECOMMENDATIONS
Prerequisites established in the study planB1 English level is required to enrol in this subject.
We suggest to use the indicated Bibliography and all the additional information provided along the course.
Recommendations
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BIOQUÍMICA PAGE 1 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
INTENDED LEARNING OUTCOMES
To make students able to show they know and understand contents in a given study area from thebasis of general secondary education, considering that this information can be found at a level that,based on specialised text books, also includes some aspects that entail knowledge from the recentadvance in their study field.
CB1
Students will know how to apply their knowledge to their job or professional vocation, and willpossess the knowledge that they can demonstrate by means of developing and defending arguments,and solving problems within their area of study.
CB2
To make the students able to obtain and interpret relevant data (normally within their field of study)to reflect on social, scientific and ethical topics
CB3
To make students able to share information, ideas, problems and solutions with an audience ofspecialists and non-specialists
CB4
To make students able to develop necessary learning abilities to begin further study with a highdegree of independence
CB5
Improving user-level skills in ICTCU2
Ability to correctly express oneself in the Spanish language in its disciplinary field.CT1
Ability to resolve problems.CT2
Ability to put knowledge into practiceCT4
Analysis and synthesis skills.CT7
To have developed the incentive for quality.CT10
Organisational and planning skills.CT11
Information management skills.CT12
To recognise and apply the necessary physical, chemical, biochemical, biological, physiological,mathematical and statistical principles for understanding and developing Food Science Technology.
CE1
OBJECTIVES
Study and understanding of the basis of life, in order to know the functioning of living beings at the molecularlevel, and the applications to study foods.
CONTENT
1. Theory contentsI Proteins and enzymes1. Amino acids and peptides.2. Proteins. 3. Enzymes. II Bioenergetics and introduction to metabolism4. Bioenergetics, membranes and transport.5. Intercellular communication.6. Introduction to metabolism and Krebs cycle. 7. Respiratory chain and oxidative phosphorylation. III Carbohydrates, lipids and nitrogen biomolecules metabolism8. Carbohydrates and glucidic metabolism9. Lipids and its lipid metabolism10. Metabolim of nitrogen molecules organs. Metabolic fluxes as a function of the nutrition state.
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BIOQUÍMICA PAGE 2 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTIONIV Molecular biology11. Structure of genetic material.12. Chromosomic replication13. Transcription14. Traduction 15. Regulation of gene expression.16. Short overview of the research carried out by the teachers.
CLASSROOM PRACTICESCP I. AMINO ACIDS AND PEPTIDES. Problems and questions on the acid-base properties of amino acids.Determination of pI and electrophoretic mobility of amino acids and peptides.CP II. ENZYMATIC KINETICS. Problems and questions on the bioenergetics of enzymatic catalysis. Lineweaver-Burk equation: Km and Vmax calculation. Effect of inhibitors on the kinetic parameters.CP III. BIOENERGETICS AND ENERGETIC METABOLISM. Problems and questions on basic thermodynamicconcepts, difference of potential between two redox pairs, relationship between ΔG, ΔE, Keq, activatedintermediaries and coupled reactions, Krebs cycle, respiratory chain and oxidative phosphorylation.CP IV. TRANSPORT. Problems and questions on transport bioenergetics: Na+/K+, ATPase, Ca2+-ATPase andsecondary active transport systems.CP V. BIOMOLECULES METABOLISM. Problems and questions on carbohydrate, lipids and nitrogenbiomolecules.LABORATORY PRACTICESLP1. Quantitative analysis of proteins by the Lowry method.LP2. Kinetics characterization of alkaline phosphatase.LP3. Quantitative analysis of glucose by the glucose oxidase method.LP4. Acid and enzymatic hydrolysis of glycogen.
2. Practical contents
METHODOLOGY
General clarifications on the methodology (optional)Master classes, numerical problems and practical cases related to metabolism: a final examination will be done atthe date determined by the Faculty of Veterinary, about the knowledge acquired through the magisterial lessonsand classroom practices. Its mark will represent 68% of the final mark of the subject.Classroom practices: We will work on the resolution of numerical problems and practical cases related tometabolism. Attendance and participation will be evaluated. The mark in this section will represent a 6 % of thefinal mark of the subject.Laboratory practices: we will work in the basic utilization of laboratory instruments, and also the preparation ofsolutions. Evaluation will take into account the performance, attitude and results, and also the answer to a seriesof questions at the end of each session. The mark will represent 20% of the final mark of the subject.Comprehensive reading: students will do 2 readings on matters selected by teachers, who will provide thenecessary material and specify the procedure to follow. The comprehension of these readings will be evaluated inwriting. The mark of this section will represent a 6 % of the final mark of the subject.
Methodological adaptations for part-time students and students with disabilities and specialeducational needsSpecific adaptations for part-time students will be taken into account.Students with disabilities and special educative needs will be treated according to the indications received fromthe Faculty of Veterinary, providing more time for exams whenever necessary.
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BIOQUÍMICA PAGE 3 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
Face-to-face activities
Activity Large group Medium group Total
Assessment activities 2 2 4
Case study - 15 15
Lab practice - 10 10
Lectures 31 - 31
Total hours: 33 27 60
Off-site activities
Activity Total
Activities 21
Reference search 9
Self-study 60
Total hours 90
WORK MATERIALS FOR STUDENTS
Case studiesExercises and activities - http://moodle.uco.es/m2021/Oral presentations - http://moodle.uco.es/m2021/References - http://moodle.uco.es/m2021/
EVALUATION
Intendedlearnig
Doc
um
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An
alys
is
Exa
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Pro
ble
m s
olvi
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CB1 X
CB2 X X
CB3 X X
CB4 X
CB5 X
CE1 X X
CT1 X
CT10 X X
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BIOQUÍMICA PAGE 4 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
Intendedlearnig
Doc
um
ent
An
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is
Exa
ms
Pro
ble
m s
olvi
ng
CT11 X X
CT12 X
CT2 X X
CT4 X X
CT7 X
CU2 X
Total (100%)
Minimum grade
12%
4.5
68%
4.5
20%
5(*)Minimum grade necessary to pass the course
Method of assessment of attendance:Active attendance and participation in classroom and laboratory practices will be taken into account forevaluation.
General clarifications on instruments for evaluation:A final examination will be done at the date determined by the Faculty of Veterinary on the concepts taught at themaster classes and during the classroom practices. It will represent 68 % of the final mark of the subject.Laboratory practices: Each practice will be evaluated based on the interest and participation of the student duringits realization, the obtained results and the answers to questions which will be posed after the practice has beencarried out. The mark will represent 20 % of the total of the subject.Comprehensive reading and classroom practices: The comprehension of every reading will be evaluated in written.The mark in this section will represent 6 % of the final mark of the subject. In the classroom practices, attendanceand participation will be evaluated. The mark of this section will be 6 % of the final mark of the subject.The subject is passed with a mark of 5. It is required to have at least 45% of the points from the master classesand numeric problems, and a 50% of the points from laboratory practices. All parts of the program should bebalanced. The final mark will include the total of points obtained in the different activities, upon condition offulfilling the previously indicated requirements.
Clarifications on the methodology for part-time students and students with disabilities andspecial educational needs:Specific considerations for part time students and students with especial needs will be taken into account. Theoverall evaluation system will be the same as for the rest of students.
Qualifying criteria for obtaining honors:It will be reserved for students obtaining a mark equal or higher than 9.0 without being more than 5 % of theenrolled students. Honors will be given according to the obtained mark and to the continual evaluation fromteachers along the course.
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BIOQUÍMICA PAGE 5 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
BIBLIOGRAPHY
EspañolStryer L, Berg JM, Tymoczko JL (2013) Bioquímica con aplicaciones clínicas (7a edición). Editotial Reverté. NelsonDL, Cox MM (2018) Lehninger, Principios de Bioquímica (7a edición). Ediciones Omega.Voet D, Voet JG, Pratt (2016) Fundamentos de Bioquímica: La vida a nivel molecular (4a edición). EdictorialMédica Panamericana.EnglishBerg JM, Tymoczko JL, Gatto GJ, Stryer L (2019) Biochemistry (9th Ed). MacMillan.Nelson DL, Cox MM (2017) Lehninger Principles of Biochemistry. (7th Ed). MacMillan.Voet D, Voet JG, Pratt (2016) Fundamentals of Biochemistry: Life at the Molecular Level (5th Ed). Wiley.
1. Basic Bibliography
2. Further readingEspañolDevlin TM (2015) Bioquímica. Libro de texto con aplicaciones clínicas (5a edición). Editorial Reverte.EnglishDevlin TM (2011) Textbook of Biochemistry with clinical correlations. (7th Ed) Wiley. Garrett RH, Grisham CM(2016) Biochemistry (6th Ed). Cengage Learning, Inc.
COORDINATION CRITERIA
Tasks performance
SCHEDULE
Period
Ass
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acti
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Cas
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Lab
pra
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Lec
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1# Week 0,0 0,0 0,0 2,0
2# Week 0,0 3,0 0,0 3,0
3# Week 0,0 0,0 0,0 3,0
4# Week 1,0 0,0 2,5 3,0
5# Week 0,0 3,0 0,0 2,0
6# Week 0,0 0,0 2,5 2,0
7# Week 2,0 3,0 0,0 2,0
8# Week 0,0 0,0 2,5 2,0
9# Week 1,0 3,0 0,0 2,0
10# Week 0,0 0,0 2,5 2,0
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BIOQUÍMICA PAGE 6 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
Period
Ass
essm
ent
acti
viti
es
Cas
e st
udy
Lab
pra
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Lec
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s
11# Week 0,0 3,0 0,0 2,0
12# Week 0,0 0,0 0,0 2,0
13# Week 0,0 0,0 0,0 2,0
14# Week 0,0 0,0 0,0 2,0
Total hours: 4,0 15,0 10,0 31,0
The methodological strategies and the evaluation system contemplated in this Course Description will be adapted according tothe needs presented by students with disabilities and special educational needs in the cases that are required.
CONTINGENCY PLAN: CASE SCENARIO A
Case scenario A will correspond to a diminished on-site academic activity due to social distancingmeasures affecting the permitted capacity of classrooms.
General clarifications on the methodology on case scenario AA multimodal (hybrid) teaching system will be adopted, combining both on-site and remote classes viavideoconference (synchronous) that will be held in the timetable approved by the corresponding Faculty or School.The time distribution of teaching activities (both on-site and remote) will be decided by the aforementionedFaculties and Schools bearing in mind the permitted capacity of classrooms and social distancing measures asestablished at that time.Master classes: a final examination will be done at the date determined by the Faculty of Veterinary, about theknowledge acquired through the magisterial lessons.Classroom practices: On the resolution of numerical problems and practical cases related to the topic. Laboratory practices: we will work on the basic utilization of laboratory instruments, and also the preparation ofsolutions.Comprehensive reading: students will do 2 readings on matters selected by teachers, who will provide thenecessary material and specify the procedure to follow.
METHODOLOGY
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BIOQUÍMICA PAGE 7 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
EVALUATION
Intendedlearnig
Doc
um
ent
An
alys
is
Exa
ms
Lab
orat
ory
Pra
ctic
e
Pro
ble
m s
olvi
ng
CB1 X
CB2 X X X
CB3 X X X
CB4 X
CB5 X
CE1 X X X
CT1 X
CT10 X X X
CT11 X X X
CT12 X
CT2 X X X
CT4 X X
CT7 X
CU2 X
Total (100%)
Minimum grade
11%
4
55%
4
16%
4
18%
4(*)Minimum grade necessary to pass the course
Active attendance and participation in classroom and laboratory practices will be taken into account forevaluation.
Method of assessment of attendance (Scenario A):
A final examination will be done at the date determined by the Faculty of Veterinary on the concepts taught at themaster classes. It will represent a maximum of 55 % of the final mark of the subject.Laboratory practices: Each practice will be evaluated based on the interest and participation of the student duringits realization, the obtained results and the answers to questions which will be posed after the practice has beencarried out. Document analysis (Comprehensive reading and classroom practices): The comprehension of every reading will beevaluated in written. The mark in this section will represent 6 % of the final mark of the subject. In the classroompractices, attendance and participation will be evaluated by a questionaire at the end of the session. The mark ofthis section will be 5 % of the final mark of the subject.
General clarifications on instruments for evaluation (Scenario A):
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BIOQUÍMICA PAGE 8 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTIONThe subject is passed with a mark of 5. It is required to have at least 40% of the points from each evaluationinstrument. The mark for each part of the program should be balanced. The final mark will include the total ofpoints obtained in the different activities, upon condition of fulfilling the previously indicated requirements.
Clarifications on the methodology for part-time students and students with disabilities andspecial educational needs (Scenario A):Specific considerations for part time students and students with especial needs will be taken into account. Theoverall evaluation system will be the same as for the rest of students.
Qualifying criteria for obtaining honors (Scenario A):It will be reserved for students obtaining a mark equal or higher than 9.0 without being more than 5 % of theenrolled students. Honors will be given according to the obtained mark and to the continual evaluation fromteachers along the course.
CONTINGENCY PLAN: CASE SCENARIO B
Case scenario B will bring about a suspension of all on-site academic activities as a consequence ofheath measures.
General clarifications on the methodology on case scenario BOn-site teaching activities will be held via videoconference (synchronous) in the timetable approved by thecorresponding Faculty or School. Alternative activities will be proposed for reduced groups in order to guaranteethe acquisition of course competences.Master classes: a final examination will be done at the date determined by the Faculty of Veterinary, about theknowledge acquired through the master classes.Classroom practices: We will work on the resolution of numerical problems and practical cases related tometabolism.Laboratory practices: we will work in the basic utilization of laboratory instruments, and also the preparation ofsolutions.Comprehensive reading: students will do 2 readings on matters selected by teachers, who will provide thenecessary material and specify the procedure to follow. The comprehension of these readings will be evaluated inwriting.
METHODOLOGY
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BIOQUÍMICA PAGE 9 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
EVALUATION
Intendedlearnig
Doc
um
ent
An
alys
is
Exa
ms
Lab
orat
ory
Pra
ctic
e
Pro
ble
m s
olvi
ng
CB1 X
CB2 X X X
CB3 X X X
CB4 X
CB5 X
CE1 X X X
CT1 X
CT10 X X X
CT11 X X
CT12 X
CT2 X X X
CT4 X X
CT7 X
CU2 X
Total (100%)
Minimum grade
11%
4
55%
4
16%
4
18%
4(*)Minimum grade necessary to pass the course
Active attendance and participation in classroom and laboratory practices will be taken into account forevaluation.
Method of assessment of attendance (Scenario B):
Moodle Tools An
ális
is d
edo
cum
ento
s
Exá
men
es
Prá
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as d
ela
bora
tori
o
Res
olu
ción
de
prob
lem
as
Asistencia X
Cuestionario X X X X
Encuestas y encuesta predefinida X X
Tarea X
Videoconferencia X X X
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BIOQUÍMICA PAGE 10 11/ 2020/21 Year
2020/21 YearFACULTAD DE VETERINARIA
COURSE DESCRIPTION
General clarifications on instruments for evaluation (Scenario B):A final examination will be done at the date determined by the Faculty of Veterinary on the concepts taught at themaster classes. It will represent a maximum of 55 % of the final mark of the subject.Laboratory practices: Each practice will be evaluated based on the interest and participation of the student duringits realization, the obtained results and the answers to questions which will be posed after the practice has beencarried out. The mark obteined per session will represent 4% % of the total of the subject. Document analysis (Comprehensive reading and classroom practices): The comprehension of every reading will beevaluated in written. The mark in this section will represent 6 % of the final mark of the subject. In the classroompractices, attendance and participation will be evaluated by a questionaire at the end of the session. The mark ofthis section will be 5 % of the final mark of the subject.The subject is passed with a mark of 5. It is required to have at least 40% of the points from each evaluationinstrument. The mark for each part of the program should be balanced. The final mark will include the total ofpoints obtained in the different activities, upon condition of fulfilling the previously indicated requirements.
Specific considerations for part time students and students with especial needs will be taken into account. Theoverall evaluation system will be the same as for the rest of students.
Clarifications on the methodology for part-time students and students with disabilities andspecial educational needs (Scenario B):
Qualifying criteria for obtaining honors (Scenario B):It will be reserved for students obtaining a mark equal or higher than 9.0 without being more than 5 % of theenrolled students. Honors will be given according to the obtained mark and to the continual evaluation fromteachers along the course.
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BIOQUÍMICA PAGE 11 11/ 2020/21 Year