febrile convulsion febrile convulsion dr f. ashrafzadeh dr f. ashrafzadeh 3/7/90 3/7/90
TRANSCRIPT
Definition of F.CDefinition of F.C
Occur between 6 mo – 6 y
With T>38°c or more
Not result of CNS infectious or metabolic dis..
Incidence: 2-5%
Classification:
Simple F.C Complex F.C >15’ , focal, recur within 24 hr Febrile status epilepticus >30'
Recurrence of F.C
30% after a first episode
50% after 2 or more episode or in infant less than 1 years
Risk factors for recurrence of F.CRisk factors for recurrence of F.C
Major: Age < 1 y Duration of fever< 24 hr Fever 38-39°c Minor: Familial hx of F.C Day care Familial hx of epilepsy Male Complex F.C Low Na
Risk factors for recurrence of F.CRisk factors for recurrence of F.C
con’t:
1 risk factor……. 12% recurrence
2 risk factors…... 25-50% recurrence
3 risk factors…... 73-100% recurrence
Types of epilepsy can be preceded by F.C:
Severe myoclonic epilepsy of infancy
( Dravet syndrome ) Generalized epilepsy with F.C
( GEFS+) Temporal lobe epilepsy
( mesial temporal sclerosis )
GEFS+:GEFS+:
A.D syndrome Early childhood Generalized epilepsy (GTCS, absence, myoclonic atonia, myoclonic astatic)
Dravet syndrome:Dravet syndrome:
Severe form of epilepsy Onset in 1st year of life Febrile or afebrile unilateral clonic seizures During 2 yrs seizure occur Makes developmental delay A.D gene is located 2q24-31 Most patients with vaccine encephalopathy have Dravet syn
Risk factors for recurrence of epilepsyRisk factors for recurrence of epilepsy
Simple F.C 1%
Developmental delay 33%
Focal complex F.C 29%
Familial hx of epilepsy 18%
Fever 1 hr before attacks 11%
Complex febrile seizures 6%
Recurrent F.C 4%
Lumbar puncture:Lumbar puncture:
In children less than 18 m.o
In children has received A/B
Signs and symptoms of meningitis
EEG in F.C:
When epilepsy is highly suspected
To know the type of epilepsy
It can’t delineate F.C occurrence
Must be done after 2 weeks
Paraclinical studies:Paraclinical studies:
• Blood studies is not recommended unless…..•B.S if prolonged postictal obtundation
•Neuroimaging is not recommended
Treatment:Treatment:
If seizure last more than 5 minutes….. give DZM
Oral DZM 0.3 mg/kg q8h during fever
Chronic antiepileptic therapy in greater risk group
Iron deficiency increases F.C