1

FINAL PROGRAM

FINAL PROGRAM

2

Dear Colleagues,

We are pleased to invite you to join us at the 11th Annual Scientific Congress of the European Cardiac Arrhythmia Society “ECAS” to be held in Paris, France April 19 to 21, 2015 at the Meridien-Etoile Hotel. All those who attended previous editions of ECAS Congress know that it is a highly scientific and educational event in a cheerful atmosphere which facilitates the interaction between the renowned faculty and younger colleagues in the field. This edition promises to be particularly successful and we will be delighted to welcome you in Paris next spring.

Riccardo Cappato, MD Xavier Jouven, MD Nicolas Lellouche, MD President of ECAS Scientific Program Chair Congress Chairman

Executive Committee of the European Cardiac Arrhythmia Society President Riccardo Cappato (Milan, IT) Past President Wyn Davies (London, GB) Vice-President (Education & Research) Richard Hauer (Utrecht, NL) Vice-President (National Societies) Massimo Santini (Rome, IT) Vice-President (International Societies & EU) Samuel Lévy (Marseille, FR) Treasurer Eli Ovsyshcher (Beersheba, IL) Secretary General Leo Van Wersch (Paris, FR) Continuing Medical Education Nicholas Peters (London, GB) Relation with European Societies Stefan Kaab (Munich, DE) Chair Membership Program Neil Sulke (Eastbourne, GB) Organizing annual Congress Gerhard Steinbeck (Munich, DE) Education Committee Thorsten Lewalter (Munich, DE)

3

Organizing Committee ECAS 2015 Riccardo Cappato, Wyn Davies, Xavier Jouven, Stefan Kääb, Nicolas Lellouche, Samuel Lévy (Chair), Michael Nabauer, Gerhard Steinbeck, Reza Wakili

Riccardo Cappato, MD Samuel Lévy, MD Gerhard Steinbeck, MD

Program Committee Andrey Ardashev ; Alawi Alsheikh-Ali ; Serge Barold ; David S Cannom ; Riccardo Cappato ; Wyn Davies ; Roberto De Ponti ; Heidi Estner ; Jeronimo Farre ; Mark Estes III ; John Fisher; Robert Hatala ; Richard Hauer ; Ellen Hoffmann ; Charles Jazra ; Xavier Jouven (Chair) ; Stefan Kaab ; Jean-François Leclercq ; Gilles Lascault ; Samuel Lévy ; Thorsten Lewalter ; Shaowen Liu ; Peter Loh ; Pierpaolo Lupo ; Chang Sheng Ma ; Michael Nabauer ; Mohan Nair ; Yuji Nakazato ; Andrea Natale ; Petr Neuzil ; Eli Ovsyshcher ; Douglas L Packer ; Luigi Padeletti ; Nicholas S. Peters ; Dubravko Petrac ; Antonio Raviele ; Amiran Revishvilli ; Sanjeev Saksena ; Gerhard Steinbeck ; Massimo Santini ; Neil Sulke ; Dorwarth Uwe ; Reza Wakili ; Bruce Wilkoff.

Scientific Advisory Board

Masood Akhtar (Milwaukee, USA) Stephen C. Hammill (Rochester, MN, USA) Oscar Oseroff (Buenos Aires, AR)

Etienne Aliot (Nancy, FR) Richard Hauer(Utrecht, NL) Ali Oto (Ankara, TR)

Maurits A. Allessie (Maastricht, NL) Habib Haouala (Tunis, TN) Eli Ovsyshcher (Beersheba, IL)

Eckhard Alt (Munich, DE) Stefan Hohnloser(Frankfurt, DE) Douglas L. Packer (Rochester, USA)

Charles Antzelevitch (Utica, USA) Yoshito Iesaka (Tokyo, JP) Luigi Padeletti (Florence, IT)

Andrey Ardashev (Moscow, RU) Charles Jazra (Beirut, LB) Nicholas S Peters, (London, GB)

Serge S. Barold (Boca Raton, USA) Werner Jung (Villingen, DE) Dubravko Petrac (Zagreb, HR)

David Benditt (Minneapolis, USA) Joergen Kanters (Copenhagen, DK) Eric N. Prystowsky (Indianapolis, USA)

Poul Erik Bloch-Thomsen (Hellerup, DK) Gilbert Kirkorian (Lyon, FR) Antonio Raviele(Venice, IT)

Johannes Brachmann (Coburg, DE) Bondo Kobulia (Tbilisi, GE) Amiran Revishvili (Moskow, RU)

A John Camm (London, GB) Karl-Heinz Kuck (Hamburg, DE) Dwight Reynolds (Oklahoma, USA)

Riccardo Cappato (Milan, IT) Antoine Leenhardt (Paris, FR) Edward Rowland (London, GB)

David S. Cannom (Los Angeles, USA) Jean-François Leclercq (Paris, FR) Sanjeev Saksena (New Brunswick,USA)

Stuart J. Connolly (Hamilton, CA) Jean-Yves Le Heuzey (Paris, FR) Massimo Santini (Rome, IT)

Antonio Curnis (Brescia, IT) Samuel Lévy (Marseille, FR) Maurizio Santomauro (Naples, IT)

Philippe Coumel* Berndt Luderitz (Bonn, DE) Dipen Shah (Geneva, CH)

D. Wyn Davies (London, GB) Damian Gascon Lopez (Sevilla, ES) Martin Jan Shalij (Leiden, NL)

Hu Dayi (Beijing, CN) Marek Malik (London, GB) Richard Schilling (London, GB)

Luc De Roy (Yvoir, BE) Sherif Mokhtar (Cairo, EG) Georg Schmidt (Munich, DE)

Sergio Dubner (Buenos Aires, AR) Harry G. Mond (Melbourne, AU) Peter M. Spooner (Baltimore, USA)

Nils G. Edvardsson (Goteborg, SE) Alessandro A Montenero (Rome, IT) Neil Sulke (Eastbourne, GB)

Michaël Eldar (Tel Aviv, IL) Conception Moro Serrano (Madrid, ES) Paul Touboul (Lyon, FR)

4

Nabil El-Sherif (New York, USA) Arthur J. Moss (Rochester, NY, USA) Albert Waldo (Cleveland, USA)

Jeronimo Farre (Madrid, ES) Gerald V. Nacarelli (Hershey, USA) Hein JJ Wellens (Maastricht, NL)

John Fisher (New-York, USA) Franco Nacarella (Bologna, IT) Bruce Wilkoff (Cleveland, USA)

Guy Fontaine (Paris, FR) Yuji Nakazato (Tokyo, JP) George D. Wyse (Calgary, CA)

Robert Frank (Paris, FR) Andrea Natale (Cleveland, USA)

Seymour Furman (New York, USA)* Promund I. W.Obel (Johannesburg, ZA) *In memoriam

Bulent Gorenek (Eskisehir, TR) Bertil S. Olsson (Lund, SE)

Mohamed Guediche (Tunis, TN)

5

Abstract Selection

The Organizing committee would like to thank the abstract reviewers for their valuable help in abstract selection of ECAS 2015 program: Etienne Aliot; Elad Anter; Serge Barold; Jean-Jacques Blanc; Poul-Erik Block Thomsen; Gerard

Boink; Gunter Breithardt; Hugh Calkins; Leonardo Calo; John Camm; Riccardo Cappato; Mario

Delmar; Roberto De Ponti; Luigi Di Biase; Nils Edvardsson; Nabil El Sherif; Mark Estes; Heidi

Estner; Gerard Guiraudon; Sam Hanon; Richard Hauer; Bengt Herweg; Ellen Hoffman; Carsten

Israel; Michiel Janse; Prapa Kanagaratnam; Helmut Klein; Yusuke Kondo; Jean-Yves Le Heuzey;

Nicolas Lellouche; Thorsten Lewalter; Berndt Lüderitz; Marek Malik; Robert Myerburg; Yuji

Nakazato; Brian Olshansky; Ali Oto; Eli Ovshyscher; Dubravko Petrac; Sanjeev Saksena; Walid

Saliba; Massimo Santini; Peter Schwartz; Robert Schweikert; Dipen Shah; Claudio Shuger; Jasbir

Sra; Gerhard Steinbeck; Neil Sulke; Richard Sutton; Tamas Szili-Torok; Jacob Tfelt-Hansen;

Antonello Vado; Peter Van Tintelen; Reza Wakili; Albert Waldo; David Wilber; Bruce Wilkoff; Roger

Winkle.

Congress Chairman

Nicolas Lellouche, MD

Hôpital Henri Mondor

51 avenue du Maréchal

de Lattre De Tassigny

94000 Créteil, France

Email: nicolas.lellouche@hmn.aphp.fr

Abstract Awards

Abstracts for the Best oral abstracts will be presented during the Opening Ceremony to take place on Sunday April 19, 2015 at Room Derain. Presentation of the Awards for Best Poster Presentations will take place on Tuesday April 21, 2015 12:00pm-12:30pm Room Diderot (Meridien-Etoile Hotel)

Publication

JICE (Journal of Interventional Cardiac Electrophysiology) is the official Journal of the European Cardiac Arrhythmia Society

6

JICE Sanjeev Saksena MD Leonardo Calo MD JICE Editor-in-Chief ECAS JICE co-Editor

Pre-Arranged Sessions

The Program includes 33 Pre-arranged sessions and workshops or debates. It can be downloaded from our website as well as the Program of Abstracts selected for oral or poster presentations

General information

Congress venue LE MERIDIEN ETOILE Hôtel 81 Boulevard Gouvion Saint Cyr, 75848 Paris Cedex 17 Tel: (33) (0)1 40 68 34 34 www.lemeridienetoile.com

Badges Badges and Final programs will be available at Hotel Meridien Etoile, Paris for pre-registered participants and Faculty at the ECAS welcome desk starting

Saturday April 18, 2015 from 2:00 PM to 6:00PM

Accomodation A block of rooms at a special group rate in Hotel Meridien Etoile where the Congress is taking place has been reserved for our participants. Reservation will be made on a first come first serve basis using

7

the hotel reservation form found on the website www.ecas-heartrhythm.org or by phone. Do not forget to indicate that you are attending ECAS 2015 in order to get the reduced negotiated rate. We kindly advise our participants to make reservation as soon as possible as Paris is a busy and highly appreciated destination. If needed, the secretariat of the congress will provide you with more information and help.

ECAS Congress SecretariatJosette Razafimbelo Tel: + 334 89 14 45 33 Cell: +336 26 07 55 74 E-mail: josette.razafimbelo@sfr.fr

Abstract Presentations The abstracts accepted for oral or poster presentation will be published in a supplement issue of the Journal of Interventional Cardiac Electrophysiology (JICE), the official journal of ECAS provided the authors attend the congress and present their work. The oral presentation of abstracts is 10 minutes plus 5 minutes for discussion. All posters accepted for presentation will be chaired. Please to check the day and time at which your poster will be presented to the chairpersons and the time at which the presenter should be near their poster board.

Registration Registration and payment of Congress fees as well as payment of Membership dues can be done through the website. Registration on site will start on Sunday April 19 2015 at 8:00 AM at Hotel Meridien-Etoile.

Currency Payment in cash for registration on site must be made in euros only. Payment using Visa credit cards will be accepted on the Congress site. Personal checks cannot be accepted.

Congress Website All information, Scientific Program and Registration to the congress, Abstract submission and Membership subscription with secured payment can be done through our website http://www.ecas-heartrhythm.org

8

PROGRAM AT A GLANCE ECAS 2015

SUNDAY APRIL 19, 2015 8:00am

5:00pm Registration

8:30am

10:00am

Concurrent Workshops Room

TOCQUEVILLE Room PASCAL Room DIDEROT Room DESCARTES Room GAUGUIN

Session WS-06 Five year Experience

with NOACs

Session WS-01

Atrial Fibrillation

ablation D L Packer

Session WS-02

Cardiac

Resynchronization therapy Bruce Wilkoff

Session WS-03 Pacemaker, ICD and

CRT:Case studies

S Barold

E Ovsyshcher B Herweg

Chaired poster

session A Part 1

10:00am-10:30am: Coffee break and visit tot he posters

10:30am

12:00pm

Concurrent Abstract Sessions Room

TOCQUEVILLE Room DIDEROT Room DESCARTES Room PASCAL Room GAUGUIN

Oral Abstract 1

Oral Abstract 2

Oral Abstract 3

Oral Abstract 4

Chaired Posters

Session A Part 2

12:15pm-1:45pm 12:15pm-1:45pm

Seated Luncheon Panel: NOACs - What’s new?

supported by Boehringer Ingelheim

2:00pm

3:30pm

Room DERAIN Room DIDEROT Room DESCARTES Room PASCAL Room GAUGUIN

Session AB-01 Pulmonary vein

isolation and related

strategies

Session HD-01

Inherited potentially

lethal syndromes

Session SP-07

ECAS-WSA

New frontiers in cardiac

pacing

Session SP-02

Prevention of sudden

cardiac death

Chaired poster

Session B Part 1

3:30pm - 4:00pm: Coffee break and visit to posters

4.00pm

5:30pm

Room DERAIN Room DIDEROT Room DESCARTES Room PASCAL Room GAUGUIN

Session AB-02 Session SP-03

The MADIT Trials

Session SP-04

Intracardiac imaging

Session SP-05

Stroke prevention in

atrial fibrillation

Chaired poster

Session B Part 2

Ventricular

tachycardia ablation

(I)

5:30pm

7:00pm

Room DERAIN

Opening ceremony Plenary lecture: A tribute to Philippe Coumel

By Albert Waldo (Cleveland, USA)

“The story behind the discovery of entrainment”

Chaired By Prof. Samuel LEVY (Marseille, FR) and Prof. Gerhard Steinbeck (Munich, DE) and OUTSTANDING ACHIEVEMENT AWARDS Presented by

Dr Riccardo Cappato (Milan, IT) President of ECAS Prof. Nicolas Lellouche (Paris, FR) Congress Chairman

Dr Fernand Hessel (Mulhouse, FR) President Lucien Dreyfus Foundation

9

MONDAY APRIL 20, 2015

8:30am

10:00am

Room COROT Room DIDEROT Room DESCARTES Room PASCAL Room GAUGUIN

Session SP-06 Session SP-07 HRS-ECAS Session I Session AB-03 Session C Part 1

AF: beyond stroke

prevention

Sudden cardiac death :

and left ventricular

hypertrophy (LVH)

Arrhythmogenic Cardiomyopathy I

Catheter ablation of

complex arrhythmias Chaired posters

10:00am - 10:30am: Coffee break and visit to the posters

10:30am

12:00pm

Concurent Oral Abstract sessions

Room COROT Room DIDEROT Room DESCARTES Room PASCAL Room Gauguin

Oral abstract 5

Oral abstract 6

Oral abstract 7

Oral abstract 8

Chaired Posters

Session C Part 2

12:15pm-1:45pm 12:15pm-1:45pm

Luncheon Panel 2 Suppported by Bayer Healthcare

2:00pm

3:30pm

Room COROT Room DIDEROT Room DESCARTES Room PASCAL Room GAUGUIN

Session AB-04 Current issues in

atrial fibrillation

Session HD-06

Biomarker-based

therapeutic decision

making in AF

Session HD-07

HRS-ECAS Session Arrhythmogenic Cardiomyopathy II

Session SP-15 Approaches in VT

Ablation

Session D Part 1

Chaired poster

3:30pm - 4:00pm: Coffee break and visit to the posters

4:00pm

5:30pm

Simultaneous sessions

Room COROT Room DIDEROT Room DESCARTES Room PASCAL Room GAUGUIN Session AB-05 SP-14 Session SP-13 Session HD-04 Session D Part 2

AF ablation not

targetting pulmonary

veins

8th Japan HRS-

ECAS CRT therapy Y. Nakazato

Sudden cardiac death Automatic nervous

system and

arrhythmias Chaired poster

Gdfg

5:30pm

6:15pm

Debate 1 Debate 2 Debate 3

Room COROT Room DIDEROT Room PASCAL

Successful RF ablation alone is an

acceptable treatment of VT with

EF above 30%

Rhythm control in AF the post

AFFIRM era?

Right ventricular apical pacing should be

abandoned

6:15-7:00pm GENERAL Assembly of ECAS members

10

TUESDAY APRIL 21, 2015

8:30am

1 10 :00am

Room DIDEROT Room DESCARTES Room PASCAL Room TOCQUEVILLE

Oral abstract 9

Oral abstract 10

Oral abstract 11

Oral abstract 12

10:00am - 10:30am: Coffee break

10:30am

12:00pm

Room DIDEROT Room DESCARTES Room PASCAL Room TOCQUEVILLE

Session SP-11

Unresolved questions

in cardiac arrhythmias

Session SP-12

New tools and techniques for

AF

Session WS-04

Current Issues in AF

management

Session WS-05

Nightmares in catheter

ablation

12:00pm

12:30pm Room DIDEROT Abstract Poster Presentations AWARDS

This program is sponsored by Aix-Marseille Université

11

ECAS 2015 SCIENTIFIC PROGRAM

SUNDAY APRIL 19, 2015 8:30 AM - 10:00 AM ROOM TOCQUEVILLE Workshop WS-06

Five Year Experience with NOACs: Time for a First Review Supported by Daiichi-Sankyo

Chairpersons: Riccardo Cappato (Milan, IT), Jean-Yves Le Heuzey (Paris, FR)

1. NOACs in venous thromboembolism TBA

2. Stroke prevention of AF: Respective indications of NOAcs versus LAA device closure Samuel Lévy (Marseille, France)

3. NOACs in catheter ablation

Wyn Davies (London, GB)

4. NOACs in cardioversion Riccardo Cappato (Milan, IT)

SUNDAY APRIL 19, 2015 8:30 AM - 10:00 AM ROOM PASCAL Workshop WS-01

Atrial Fibrillation Ablation: A New Generation of Approaches Chairpersons: Douglas L. Packer (Rochester, USA), Karl-Heinz Kuck (Hamburg, DE)

1. Linear cold balloon therapy for persistent atrial fibrillation Suraj Kapa (Rochester, USA)

2. Impact of Contact Force Ablation on Clinical Outcomes in Patients with Atrial

Fibrillation Dipen Shah (Geneva, CH)

3. 4-5 D Mapping for Intracardiac and Extracorporeal Ablation of AF

David Wilber (Maywood, USA)

4. The Biophysics of New Generation Cryoballoon and Contact Source Ablative Intervention Douglas L. Packer (Rochester, USA)

12

SUNDAY APRIL 19, 2015 8:30 AM - 10:00 AM ROOM DIDEROT

Workshop WS-02

Cardiac Resynchronization Therapy Improving Outcomes and Reducing Adverse events Chairpersons: Bruce Wilkoff (Cleveland, USA), Helmut Klein (Munich, DE)

1. Pre-operative assessment of CRT Responsiveness

Bruce L. Wilkoff (Cleveland, USA)

2. Impact of RV pacing vs prevention of dyssynchrony

Jean-Jacques Blanc (Brest, FR)

3. Approaches to upgrading vs avoiding CRT

Mark Estes III (Boston, USA)

4. Management of atrial fibrillation in CRT Patients: PVI or AV junctional ablation

Walid Saliba (Cleveland, USA)

5. Alternatives to the CS for left ventricular pacing

Tamas Szili-Torok (Rotterdam, NL)

SUNDAY APRIL 19, 2015 8:30 AM - 10:00 AM ROOM DESCARTES Workshop WS-03

Pacemaker ECG, ICD and CRT interpretation: Case studies

Chairpersons: Serge Barold (Tampa, USA), Eli Ovsyshcher (Beersheba, IL), Bengt Herweg (Tampa, USA)

1. Serge Barold 2. Eli Ovsyshcher 3. Bengt Herweg

SUNDAY APRIL 19, 2015 8:30 AM - 12:00 AM ROOM GAUGUIN Chaired poster session A Session A part 1 Posters exposed from 8:30 AM - 12:00 PM Presenters and chairpersons present from 09:00 AM - 10:30 AM

Supraventricular arrhythmias: advances in mechanisms and management

13

Chairpersons: Sanjeev Saksena (New Brunswick, USA), Luigi de Ambroggi (Milan, IT) 13-1 Abstract 14-19 IVABRADINE VERSUS BISOPROLOL FOR INAPPROPRIATE SINUS TACHYCARDIA Annamaria Martino 1, Antonella Sette 1, Marco Rebecchi 1, Ermenegildo de Ruvo 1, Luigi Sciarra 1, Lucia De Luca 1, Alessio Borrelli 1, Alessandro Fagagnini 1, Antonio Scarà 1, Leonardo Calo' 1 1 Cardiology Department, Policlinic Casilino, Rome, Italy 13-2 Abstract 28-15 NONINVASIVE ELECTROCARDIOGRAPHIC IMAGING OF ATRIAL FLUTTER IN HUMANS USING PHASE MAPPING Amiran Revishvili 1, Dmitry Lebedev 2, Michail Chmelevsky 2, Alexander Kalinin 3, Vitaly Kalinin 1, Evgenii Labartkava, 1, Oleg Sopov 1, Stepan Zubarev 2 1 1- Bakoulev Scientific Center for Cardiovascular Surgery, Moscow, Russia, 2 2- Almazov Federal Heart, Blood and Endocrinology Centre, St. Petersburg, Russia, 3 3- Lomonosov Moscow State University, Moscow, Russia

13-3 Abstract 28-11 ABLATION OF ATYPICAL ATRIAL FLUTTERS USING ULTRA HIGH DENSITY ACTIVATION SEQUENCE MAPPING Roger Winkle 1, Ryan Moskovitz 2, R. Hardwin Mead 1, Gregory Engel 1, Melissa Kong 1, William Fleming 1, Rob Patrawala 1 1 Silicon Valley Cardiology, E Palo Alto, CA, United States, 2 St. Jude Medical, St. Paul, MN, United States

13-4 Abstract 28-13 FEASIBILITY OF USING RIPPLE MAPPING IN A CONSECUTIVE SERIES OF ATRIAL TACHYCARDIA ABLATIONS Vishal Luther 1, Shahnaz Jamil-Copley 1, Nicholas Linton 1, Michael Koa-Wing 1, Sajad Hayat 1, Norman Qureshi 1, Fu-Siong Ng 1, Belinda Sandler 1, Kevin Leong 1, Ian Wright 1, Zachary Whinnett 1, Phang Boon Lim 1, David Lefroy 1, David Wyn Davies 1, Nicholas Peters 1, Prapa Kanagaratnam 1 1 Imperial College Healthcare NHS Trust, London, United Kingdom

13-5 Abstract 18-31 USE OF ELECTRICAL COUPLING INDEX IN TYPICAL ATRIAL FLUTTER ABLATION Massimiliano Maines 1, Domenico Catanzariti 1, Carlo Angheben 1, Maurizio Del Greco 1 1 Santa Maria del Carmine Hospital, Rovereto, Italy 13-6 Abstract 14-17 INTERVENTIONAL TREATMENT SUPRAVENTRICULAR TACHYARRHYTHMIAS IN CHILDREN WITH CONGENITAL HEART DISEASE Elena Artyukhina 1, Amiran Revishvili 1 1 Bakulev Scientific Center for Cardiovascular Surgery, Moscow, Russia

13-7 Abstract 08-12 CLINICAL IMPLICATION OF UNIPOLAR RECORDING FOR THE SLOW PATHWAY MAPPING IN PATIENT WITH TYPICAL AV NODE RE-ENTRY TACHYCARDIA AND PROLONGED PR INTERVAL Andrey Ardashev 1, Evgeny Zhelyakov 1 1 Federal Scientific and Clinical Centre, Moscow, Russia

14

13-8 Abstract 01-10 ADENOSINE SENSITIVITY OF RETROGRADE FAST PATHWAY CONDUCTION IN PATIENTS WITH SLOW-FAST ATRIOVENTRICULAR NODAL REENTRANT TACHYCARDIA: A PROSPECTIVE STUDY Elena Efimova 1, Sam Riahi 2, Yan Huo 1, Andreas Bollmann 1, Masahiro Esato 3, Thomas Gaspar 1, Philipp Sommer 1, Christopher Piorkowski 1, Gerhard Hindricks 1, Arash Arya 1 1 Heart Center University Leipzig, Leipzig, Germany, 2 Center for Cardiovascular Research, Aalborg Hospital, Aarhus University , Aalborg, Denmark, 3 Division of Cardiovascular Medicine, Yamaguchi University School of Medicine, Ube, Yamaguchi, Japan

13-9 Abstract 13-10 EXTRACORPORAL MEMBRANE OXYGENATION SUPPORT FOR LIFE-THREATENING ATRIOVENTRICULAR REENTRY TACHYCARDIA IN A NEWBORN Fridrike Stute 1, Florian Arndt 1, Urda Gottschallk 1, Boris Hoffmann 2, Thomas S. Mir 1, Goetz C. Mueller 1, Christian Thiel 1, Rainer Kozlik-Feldmann 1 1 Department of pediatric Cardiology, Hamburg, Germany, 2 University Heart Center, Hamburg, Germany

13-10 Abstract 14-15 OUR EXPERIENCE OF RADIOFREQUENCY ABLATION OF ISTHMUS DEPENDENT ATRIAL FLUTTER IN EARLY POSTOPERATIVE PERIOD AFTER OPEN HEART SURGERY Natalia Makarova 1 , Sergey Durmanov 1 , Roman Marchenko 1, Alexander Kozlov 1, Vladlen Bazilev 1 1 Federal Center of Cardiovascular Surgery, Penza, Russia

13-11 Abstract 18-17 A NEW METHOD TO DETERMINE BIDIRECTIONAL BLOCK OF THE CAVOTRICUSPID ISTHMUS Concepcion Alonso-Martin 1, Enrique Rodriguez-Font 1, Jose Guerra 1, Francisco Mendez 1, Marcos Rodriguez 1, Douglas Alvarez 1, Pelayo Torner 1, Xavier Viñolas 1 1 Hospital de Sant Pau, Barcelona, Spain 13-12 Abstract 18-34 BENEFICIAL USE OF A DUODECAPOLAR CATHETER FOR MAPPING AND ABLA-TION OF RIGHT FREE WALL ACCESSORY PATHWAYS. Yoav Michowitz 1, Aharon Glick 1, Bernard Belhassen 1 1 Cardiac Electrophysiology Laboratory, Department of Cardiology, Tel-Aviv Sourasky Med-ical Center., Tel-Aviv, Israel 13-13 Abstract 20-11 MEDIUM AND LONG TERM SIDE EFFECTS OF AMIODARONE “AMIOTOX STUDY “ Marouane Mahjoub 1, Mejdi Ben Messaoud 1, Majed Hassine 1, Wiem Selmi 1, Zohra Dridi 1, Fethi Betbout 1, Habib Gamra 1 1 Cardiology department A : Fattouma Bourguiba University Hospital, Monastir, Tunisie

13-14 Abstract 07-10 DYSRHYTHMIA IN PATIENTS WITH DIFFERENT TYPES OF ATRIAL SEPTAL DEFECTS: A COMPARISON OF INCIDENCES Charlotte Houck 1, Christophe Teuwen 1, Rik Jansen 1, Karin Kraaier 2, Jurren van Opstal 2, Joris Vriend 3, Pepijn van der Voort 4, Thelma Konings 5, Maarten Witsenburg 1, Jolien Roos-Hesselink 1, Ad Bogers 1, Natasja de Groot 1 1 Erasmus Medical Center, Rotterdam, Netherlands, 2 Medisch Spectrum Twente, Enschede, Netherlands, 3 Haga Hospital, The Hague, Netherlands, 4 Catharina Hospital, Eindhoven, Netherlands, 5 VU University Medical Center , Amsterdam, Netherlands

15

13-15 Abstract 07-11 DEVELOPMENT OF ATRIAL FIBRILLATION IN PATIENTS WITH CONGENITAL HEART DEFECTS Christophe Teuwen 1, Tanwier Ramdjan 1, Ameeta Yaksh 1, Luca Jansz 1, Dominic Theuns 1, Sander Molhoek 2, Reinhart Dorman 3, Jurren van Opstal 3, Thelma Konings 4, Joris Vriend 5, Marco Götte 5, Pepijn van der Voort 6, Etienne Delacretaz 7, John Triedman 8, Natasja de Groot 1 1 Erasmus Medical Centre, Rotterdam, Netherlands, 2 Amphia Hospital, Breda, Netherlands, 3 Medisch Spectrum Twente, Enschede, Netherlands, 4 VU Unitversity Medical Centre, Amsterdam, Netherlands, 5 Haga Hospital, The Hague, Netherlands, 6 Catharina Hospital, Eindhoven, Netherlands, 7 Inselspital, University of Bern, Bern, Switzerland, 8 Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, United States

10:00 AM - 10:30 AM Coffee break and Posters

Simultaneous abstract oral sessions SUNDAY APRIL 19, 2015 10:30 AM - 12:00 PM ROOM TOCQUEVILLE Abstract Oral Session 1

Atrial fibrillation ablation

Chairpersons: Dipen Shah (Geneva, CH), Magdi Sami (Montreal, CA)

1-1 Abstract 18-21 EFFECT OF ANTIARRHYTHMICS DRUG INITIATION ON READMISSION AFTER CATHETER ABLATION FOR ATRIAL FIBRILLATION Peter Noseworthy 1, Holly Van Houten 1, Lindsey Sangaralingham 1, Abhishek Deshmuk 1, Suraj Kapa 1, Siva Mulpuru 1, Christopher McLeod 1, Samuel Asirvatham 1, Nilay Shah 1, Douglas Packer 1 1 Mayo Clinic, Rochester, MN, United States 1-2 Abstract 18-22 CONTACT FORCE DATA AVAILABILITY REDUCES ACUTE PULMONARY VEIN RE-CONNECTION: EARLY RESULTS FROM THE SMART AF TRIAL Waqas Ullah 1, Ailsa McLean 1, Muzahir Tayebjee 2, Dhiraj Gupta 3, Matthew Ginks 4, Guy Haywood 5, Mark O'Neill 6, Pier Lambiase 7, Mark Earley 1, Richard Schilling 1, Smart AF Trial Group UK 8 1 St Bartholomew's Hospital, London, United Kingdom, 2 Leeds General Infirmary, Leeds, United Kingdom, 3 Liverpool Heart and Chest Hospital, Liverpool, United Kingdom, 4 John Radcliffe Hospital, Oxford, United Kingdom, 5 Derriford Hospital, Plymouth, United Kingdom, 6 St Thomas' Hospital, London, United Kingdom, 7 The Heart Hospital, London, United Kingdom, 8 Smart AF Trial Group, UK, United Kingdom 1-3 Abstract 18-26 PAROXYSMAL ATRIAL FIBRILLATION ABLATION WITHOUT PULMONARY VEIN ISO-LATION Clement Bars 1, Julien Seitz 2, Guillaume Theodore 3, Ange Ferracci 2, Michel Bremondy 2, Jacques Faure 2, André Pisapia 2

16

1 Institut Mutualiste Montsouris, Paris, France, 2 Hôpital Saint Joseph, Marseille, France, 3 University Hospital, Nice, France

1-4 Abstract 18-16 PREDICTION OF AF ABLATION OUTCOME: THE CAAP-AF SCORE Roger Winkle 1, Julian Jarman 2, R. Hardwin Mead 1, Gregory Engel 1, Melissa Kong 1, Wil-liam Fleming 1, Rob Patrawala 1 1 Silicon Valley Cardiology, E Palo Alto, CA, United States, 2 Royal Brompton Hospital, Lon-don, United Kingdom

1-5 Abstract 18-32 A COMBINED APPROACH OF POINT BY POINT RADIOFREQUENCY ABLATION FOL-LOWED BY CRYOBALLOON ABLATION DRAMATICALLY IMPROVES THE RATE OF LONG TERM PULMONARY VEIN ISOLATION FOR PATIENTS WITH PAROXYSMAL AF. Richard Ang 1, Aaisha Opel 1, Waqas Ullah 1, Victoria Baker 1, Malcolm Finlay 1, Mehul Dhi-noja 1, Mark Earley 1, Simon Sporton 1, Richard Schilling 1, Ross Hunter 1 1 St Bartholomew's Hospital, London, United Kingdom

1-6 Abstract 18-25 USE OF CONTACT FORCE TECHNOLOGY IN AF ABLATION PROCEDURES DOES NOT IMPROVE CLINICAL OUTCOME RATES - INSIGHTS FROM A 3 YEAR SINGLE CENTER EXPERIENCE Stefan Sattler 1, Johannes Siebermair 1, Eva Klocker 1, Lucia Olesch 1, Samira Saraj 1, Ina Klier 1, Christoph Schuhmann 1, Sebastian Clauss 1, Moritz Sinner 1, Stephanie Fichtner 1, Stefan Kääb 1, Heidi Estner 1, Reza Wakili 1 1 Medical Department I, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, Germany

SUNDAY APRIL 19, 2015 10:30 AM - 12:00 PM

ROOM DIDEROT Abstract Oral Session 2

Sudden cardiac death: prevention and management Chairpersons : Xavier Jouven (Paris, FR), Habib Haouala (Tunis, TN)

2-1 Abstract 10-13 OUTCOME OF PATIENT WITH EARLY REPOLARIZATION AFTER UNEXPLAINED SYNCOPE Mathieu Le Bloa 1, Frederic Sacher 1, Jean-Baptiste Gourraud 2, Philippe Maury 3, Gabriel Laurent 4, Christophe Leclercq 5, Jacques Mansourati 6, Dominique Babuty 7, Jean-Luc Pasquié 8, Pierre Jais 1, Nicolas Derval 1, Arnaud Denis 1, Meleze Hocini 1, Michel Haïssa-guerre 1, Vincent Probst 2 1 CHU Bordeaux, Bordeaux, France, 2 CHU Nantes, Nantes, France, 3 CHU Toulouse, Tou-louse, France, 4 CHU Dijon, Dijon, France, 5 CHU Rennes, Rennes, France, 6 CHU Brest, Brest, France, 7 CHU Tours, Tour, France, 8 CHU Montpellier, Montpellier, France

2-2 Abstract 19-24 DAYTIME AND SEASON AS PREDICTORS FOR CARDIAC RHYTHM DISTURBANCES IN DIFFERENT DISEASES – A LARGE REAL LIFE ANALYSIS Eimo Martens 1, Johannes Siebermair 1, Regina Freeden 2, Carsten Koenig 2, Stefan Veith 1, Moritz Sinner 1, Stefan Kääb 1

17

1 Klinikum der Universität München, Muenchen, Germany, 2 Medtronic GmbH, Meerbusch, Germany

2-3 Abstract 19-25 RANOLAZINE AMELIORATES POST-RESUSCITATION ELECTRICAL INSTABILITY AND MYOCARDIAL DYSFUNCTION AND IMPROVES OUTCOME IN A RAT MODEL OF VENTRICULAR FIBRILLATION Francesca Fumagalli 1, Ilaria Russo 1, Lidia Staszewsky 1, Roberto Latini 1, Antonio Zaza 2, Giuseppe Ristagno 1 1 IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy, 2 Dipartimento di Biotecnologie e Bioscienze, Università degli Studi Milano-Bicocca, Milan, Italy

2-4 Abstract 19-16 FOLLOW-UP OF PATIENTS WITH IDIOPATHIC VENTRICULAR FIBRILLATION (THE FU-IVF STUDY) – PRELIMINARY RESULTS Marloes Visser 1, Charlotte Siegers 1, Jeroen van der Heijden 1, Peter Loh 1, Pieter Doevendans 1, Rutger Hassink 1 1 UMC Utrecht, Utrecht, Netherlands

2-5 Abstract 19-26 BENEFITS OF ICD THERAPY: CONNECTING TREATMENT DECISIONS TO INDIVIDUALIZED SCD RISK ESTIMATES WITHIN SCD-HEFT - SEATTLE PROPORTIONAL RISK MODEL Wayne Levy 1, Jeanne Poole 1, Anne Hellkamp 2, Ramin Shadman 3, Todd Dardas 1, Jill Anderson 4, George Johnson 4, Daniel Fishbein 1, Daniel Mark 2, Kerry Lee 2, Gust Bardy 4 1 University of Washington, Seattle, United States, 2 Duke University, Durham, United States, 3 Southern California Permanente Medical Group, Los Angeles, United States, 4 Seattle Institute for Cardiac Research, Seattle, United States

2-6 Abstract 19-30 IMPLANTABLE CARDIAC DEFIBRILLATOR IN THE SETTING OF TETRALOGY OF FALLOT Abdeslam Bouzeman 1, Guillaume Duthoit 2, Magalie Ladouceur 1, Raphael Martins 3, Maxime De Guillebon 4, Laurent Fauchier 5, Pascal Defaye 6, Jean-Baptiste Gourraud 7, Jean-Marc Sellal 8, Pierre Mondoly 9, Fabien Lalombarda 10, Frederic Anselme 11, Linda Koutbi 12, Nicolas Lellouche 13, Franck Halimi 14, Anne Messali 15, Amel Mathiron 16, Nicolas Sadoul 8, Laurence Iserin 1, Pierre Bordachar 4, Nicolas Combes 17, Jean-Benoit Thambo 4, Eloi Marijon 1 1 Paris Cardiovascular Research Center, Inserm U970, Paris, France/European Georges Pompidou Hospital, Paris, France/Paris Descartes University, Paris, France, PARIS, France, 2 CHU La Pitie Salpetriere Hospital, Cardiology Department, Paris, France, PARIS, France, 3 CHU Pontchaillou, Cardiology Department, Rennes, France, RENNES, France, 4 CHU Haut Leveque, Cardiology Department, Bordeaux, France, BORDEAUX, France, 5 CHU Trousseau, Tours, France, TOURS, France, 6 CHU Michallon, Grenoble, France, GRENOBLE, France, 7 CHU Nantes, NANTES, France, 8 CHU Brabois, Nancy, France, NANCY, France, 9 Hopital Rangueil, TOULOUSE, France, 10 CHU CAEN, CAEN, France, 11 CHU ROUEN, ROUEN, France, 12 CHU La Timone, Marseille, France, MARSEILLE, France, 13 CHU HENRI MONDOR, CRETEIL, France, 14 HOPITAL PRIVE PARLY II, LE CHESNAY, France, 15 CHU BICHAT, PARIS, France, 16 CHU AMIENS, AMIENS, France, 17 Clinique Pasteur, Toulouse, France, TOULOUSE, France

SUNDAY APRIL 19, 2015 10:30 AM - 12:00 PM

18

ROOM DESCARTES Abstract Oral Session 3

Atrial fibrillation and prevention of related thromboembolism

Chairpersons: John Camm (London, GB), Jean-Yves Le Heuzey (Paris, FR) 3-1 Abstract 15-25 PERSISTENT LEFT ATRIAL APPENDAGE THROMBUS IN NON VALVULAR ATRIAL FIBRILLATION AND RISK OF THROMBOEMBOLISM Omer Iqbal 1, Yassar Nabeel 1, Hardik Doshi 1, Lee Joseph 1, Prashant Bhave 1, Miriam Zimmerman 1, Michael Giudici 1 1 University of Iowa Hospitals and Clinics, Iowa city , United States 3-2 Abstract 15-57 FEASIBILITY AND SAFETY OF UNINTERRUPTED PERI-PROCEDURAL APIXABAN ADMINISTRATION IN PATIENTS UNDERGOING RADIOFREQUENCY CATHETER ABLATION FOR ATRIAL FIBRILLATION: RESULTS FROM A MULTICENTER STUDY Luigi Di Biase1, Dhanujaya Lakkireddy2, Chintan Trivedi3, Thomas Deneke4, Martin Martinek5, Sanghamitra Mohanty3, Prasant Mohanty6, Sameer Prakash7, Rong Bai3, Carola Gianni8, Rodney Horton5, Elisabeth Sigmund5, Michael Derndorfer4, Anja Schade9, Patrick Mueller10, Atilla Szoelloes5, Javier Sanchez3, Amin Al-Ahmad3, Patrick Hranitzky5, G. Joseph Gallinghouse5, Richard H. Hongo5, Salwa Beheiry10, Helmut Puererfellner5, Andrea Natale3 1. Texas Cardiac Arrhythmia Institute at St David's Medical Center and Albert Einstein College of Medicine at Montefiore Hospital, Austin and New york, TX 2. University of Kansas Medical Center, Kansas City, KS 3.Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin, TX 4. Heartcenter Bad Neustadt, Bad Neustadt, Germany 5. Elisabethinen Linz GmbH, University Teaching Hospital, Linz, Austria 6.Texas College of Osteopathic Medicine, Fort worth, TX 7. Tong Ji Hospital Tong Ji Medical College Hust, Wuhan, China 8. Texas Cardiac Arrhythmia Research, Austin, TX 9. Northern California Heart Care, San Francisco, CA 10. California Pacific Medical Center, San Francisco 3-3 Abstract 15-28 HYPERACUTE AND CHRONIC CHANGES IN CEREBRAL MAGNETIC RESONANCE IMAGES AFTER PVAC, NMARQ AND EPICARDIAL THORACOSCOPIC SURGICAL ABLATION FOR PAROXYSMAL ATRIAL FIBRILLATION Conn Sugihara 1, Neil Barlow 1, Emma Owens 1, David Sallomi 1, Steve Furniss 1, Neil Sulke 1 1 East Sussex Healthcare NHS Trust, Eastbourne, United Kingdom

3-4 Abstract 15-51 RIVAROXABAN AND TWO DOSAGES DABIGATRAN VERSUS WARFARIN IN PATIENTS WITH HIGH RISK OF STROKE AND EMBOLISM UNDERGOING ELECTRICAL CARDIOVERSION WITH PERSISTENT AND LONG-ACTING ATRIAL FIBRILLATION Oskars Kalejs 1, Olga Litunenko 2, Aldis Strelnieks 3, Sandis Sakne 1, Milana Zabunova 1, Marina Kovalova 4, Galina Dormidontova 5, Iveta Sime 6, Natalija Pontaga 5, Kaspars Kupics 1, Maija Vikmane 1, Janis Guslens 7, Aivars Lejnieks 3, Andrejs Erglis 1 1 P.Stradins Clinical University Hospital, Riga, Latvia, 2 Riga Stradins University, Riga, Latvia, 3 Riga East University Hospital, Riga, Latvia, 4 Jelgava Regional Hospital, Jelgava, Latvia, 5 Daugavpils Regional Hospital, Daugavpils, Latvia, 6 Liepaja Regional Hospital, Liepaja, Latvia, 7 Riga Technical University, Riga, Latvia

19

3-5 Abstract 15-36 SINUS RHYTHM AND QUALITY OF LIFE IN THE AGE OF MODERN THERAPIES FOR ATRIAL FIBRILLATION: RESULTS FROM THE PREFER IN AF REGISTRY Liang-han Ling 1, Hunter Ross 1, Waqas Ullah 1, Alex Breitenstein 1, Finlay Malcolm 1, Aaisha Opel 1, Sarah Horan 1, Bernd Brüggenjürgen 2, Harald Darius 3, Raffaele De Caterina 4, Kamran Iqbal 5, Jean-Yves Le Heuzey 6, Paulus Kirchhof 7, Josef Schmitt 8, Jose Luis Zamorano 9, Richard Schilling 1 1 St Bartholomew's Hospital, London, United Kingdom, 2 Steinbeis-University, Institute for Health Economics, Berlin, Germany, 3 Vivantes Hospital, Berlin, Germany, 4 University Chieti-Pescara, Cardiology, Pisa, Italy, 5 Daiichi-Sankyo UK Ltd, Gerrards Cross, United Kingdom, 6 Georges Pompidou Hospital, René Descartes University, Paris, France, 7 University of Birmingham, Birmingham, United Kingdom, 8 Daiichi-Sankyo, Munich, Germany,

9

University Hospital Ramón y Cajal, Madrid, Spain

3-6 Abstract 15-33 PRIMARY PERIPHERAL ARTERY EMBOLISM: ATRIAL FIBRILLATION RELATED RISK-STRATIFICATION AND RECURRENT EMBOLIC EVENTS DURING LONG-TERM FOLLOW-UP. Christian Möllenhoff 1, Dirk Bastian 2, Athanasios Katsargyris 1, Konrad Göhl 2, Eric L. G. Verhoeven 1 1 Paracelsus Medical University; Nuremberg Hospital; Dept. of Vascular and Endovascular Surgery, Nuremberg, Germany, 2 Paracelsus Medical University; Nuremberg Hospital; Dept. of Cardiology/Rhythmology, Nuremberg, Germany

SUNDAY APRIL 19, 2015 10:30 AM - 12:00 PM

ROOM PASCAL Abstract Oral Session 4

Mechanisms of ventricular arrhythmias Chairpersons: Dobromir Dobrev (Essen, DE), Renée Sullivan (Columbia, USA)

4-1 Abstract 01-12 PREVALENCE OF RIGHT VENTRICULAR ENDOCARDIAL BIPOLAR LATE POTENTI-ALS IN BRUGADA SYNDROME Luigi Sciarra 1, Ermenegildo De Ruvo 1, Chiara Lanzillo 1, Alessio Borrelli 1, Antonio Scarà 1, Marco Rebecchi 1, Alessandro Fagagnini 1, Marta Marziali 1, Lucia De Luca 1, Domenico Grieco 1, Ludovica Scialla 2, Elisa Salustri 3, Annamaria Martino 1, Leonardo Calò 1 1 Cardiologia - Policlinico Casilino, Italia, Italy, 2 Cardiologia - Policlinico Umberto I, Rome, Italy, 3 Cardiologia - Università de L'Aquila, L'Aquila, Italy

4-2 Abstract 02-11 SLOWING OF CONDUCTION VELOCITY VIA GAP-JUNCTIONAL UNCOUPLING IS SUFFICIENT TO CAUSE ELECTROGRAM FRACTIONATION Shaun Selvadurai 1, Emmanuel Dupont 1, Caroline Roney 1, Norman Qureshi 1, Fu Siong Ng 1, Rasheda Chowdhury 1, Nicholas Peters 1 1 Imperial College London, LONDON, United Kingdom

4-3 Abstract 01-16 GAP JUNCTION UNCOUPLING DURING ISCHAEMIA ACTIVATES NORMALLY QUIESCENT PURKINJE-MYOCARDIAL JUNCTIONS RESULTING IN MORE COMPLEX ACTIVATION PATTERNS Fu Siong Ng 1, Elham Behradfar 2, Michael T Debney 1, Anders Nygren 2, Adam Hartley 1, Alexander Lyon1, Igor Efimov 3, Edward Vigmond 4, Nicholas S Peters 1

20

1 Imperial College London, London, United Kingdom, 2 University of Calgary, Calgary, Canada, 3 Washington University in Saint Louis, Saint Louis, United States, 4 Universite Bordeaux 1, Bordeaux, France

4-4 Abstract 02-14 CELLULAR CHARACTERISATION OF STROMAL CELL AND CARDIOMYOCYTE COUPLING AT THE CRITICAL ISTHMUS IN AN IN VIVO SWINE MODEL OF POST-INFARCTION RE-ENTRANT VENTRICULAR TACHYCARDIA Tarvinder Dhanjal 1, Nicolas Lellouche 2, Chris Von Ruhling 1, David Edwards 1, Chris George 1, Alan Williams 1 1 Wales Heart Research Institute, Cardiff, United Kingdom, 2 Henri Mondor Hopital, Paris, France

4-5 Abstract 01-23 THE DEVELOPMENT OF A NOVEL SYSTEM FOR THE STUDY OF CARDIAC ARRHYTHMIA – SIMULTANEOUS MEASUREMENT OF CALCIUM TRANSIENTS AND ELECTRICAL ACTIVITY IN MURINE CARDIAC TISSUE Alastair Yeoh 1, Malcolm Finlay 2, Naomi Anderson 3, Stephen Harmer 3, Andrew Tinker 3 1 UCL and QMUL, London, United Kingdom, 2 Barts Health NHS Trust and QMUL, London, United Kingdom, 3 QMUL, London, United Kingdom

4-6 Abstract 17-13 MELATONIN AND OMACOR INCREASE THRESHOLD TO INDUCE VF AND NORMALIZE MYOCARDIAL CONNEXIN-43 EXPRESSION IN FEMALE RATS EXPOSED TO HIGH SUCROSE DIET. Tamara Benova 1, Csilla Viczenczova 1, Jana Radosinska 2, Vladimir Knezl 3, Barbara Bacova 1, Jana Navarova 3, Branislav Obsitnik 4, Jan Slezak 1, Narcisa Tribulova 1 1 Institute for Heart Research, Slovak Academy of Sciences, Bratislava, Slovakia, 2 Institute of Physiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia, 3 Institute of Experimental Pharmacology & Toxicology, Slovak Academy of Sciences, Bratislava, Slovakia, 4 St. Elisabeth Institute of Oncology, Bratislava, Slovakia

SUNDAY APRIL 19, 2015 8:30 AM - 12:00 AM ROOM GAUGUIN Chaired poster session A Session A part 2 Posters exposed from 8:30 AM - 12:00 PM Presenters and chairpersons present from 10:30 AM - 12:00 PM

Atrial fibrillation characteristics and management Chairpersons: Albert Waldo (Cleveland, USA), Yuji Nakazato (Chiba, JP) 13-16 Abstract 20-10 THE EFFECT OF CRP REDUCTION WITH A HIGHLY SPECIFIC ANTISENSE OLIGONUCLEOTIDE ON PAROXYSMAL ATRIAL FIBRILLATION ASSESSED USING BEAT-TO-BEAT PACEMAKER HOLTER FOLLOW UP Conn Sugihara 1, Nick Freemantle 2, Steven Hughes 3, Steve Furniss 1, Neil Sulke 1 1 East Sussex Healthcare NHS Trust, Eastbourne, United Kingdom, 2 University College London, London, United Kingdom, 3 ISIS Pharmaceuticals, Carlsbad, United States

13-17 Abstract 15-44 QUICK INFUSION VS REPEATED INTRAVENOUS BOLUSES OF FLECAINIDE FOR

21

ATRIAL FIBRILLATION TERMINATION: A SINGLE-BLIND,TREATMENT REGIMEN CONTROLLED TRIAL. Saverio Lavanga 1, Daniele Nassiacos 1 1 Saronno Hospital-AO Busto Arsizio (VA), Pogliano Milanese, Italy

13-18 Abstract 21-11 ATRIAL FIBRILLATION "BURDEN" ON THERAPY IS RELATED TO OUTCOMES ON ANTIARRHYTHMIC DRUG THERAPY Sanjeev Saksena 1, April Slee 1, Rangadham Nagarakanti 1, Marwan Saad 1 1 Electrophysiology research Foundation, Warren, United States

13-20 Abstract 15-22 ELECTRICAL CONNECTIONS BETWEEN IPSILATERAL PULMONARY VEINS MIGHT BE EASILY IDENTIFIED USING A SPECIFIC PACING MANEUVER Concepcion Alonso-Martin 1, Jose Guerra 1, Enrique Rodriguez-Font 1, Marcos Rodriguez 1, Douglas Alvarez 1, Pelayo Torner 1, Francisco Mendez 1, Xavier Viñolas 1 1 Hospital de Sant Pau, Barcelona, Spain

13-21 Abstract 15-21 CONSISTENCY OF QTC MEASUREMENTS IN ATRIAL FIBRILLATION PATIENTS BEFORE AND AFTER CARDIOVERSION Vincent Jacquemet 1, Bruno Dubé 2, Omar Mahiddine 2, Alain Vinet 1, Aimé-Robert LeBlanc 2, Marcio Sturmer 2, Giuliano Becker 2, Teresa Kus 2, Réginald Nadeau 2 1 Université de Montréal, Montréal, Canada, 2 Hôpital du Sacré-Coeur de Montréal, Montréal, Canada

13-22 Abstract 15-20 MINIMIZING RADIATION EXPOSURE USING REMOTE MAGNETIC CATHETER NAVIGATION FOR PULMONARY VEIN ISOLATION IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION Dirk Bastian 1, Johannes Schwab 2, Andrea Brinker-Paschke 1, Arno Boessenecker 1, Wolfgang Kirste 1, Reinhard Doering 1, Zeynep Karakurt 1, Matthias Pauschinger 1, Konrad Göhl 1 1 Div. of Cardiology / Electrophysiology, Paracelsus Medical University Nuremberg, Nuremberg, Germany, 2 Div. of Cardiology and dpt. for Radiology/Neuroradiology, Paracelsus Medical University Nuremberg, Nuremberg, Germany

13-23 Abstract 15-24 ACUTE MANAGEMENT OF ATRIAL FIBRILLATION IN ELDERLY: IS THERE A PLACE FOR IMPROVEMENT? Antonio Bonora 1, Gianni Turcato 2, Elena Franchi 3, Piero Castiglioni 1, Giulio Trecco 2, Federico Beltrame 3, Oliviero Olivieri 4, Claudio Pistorelli 1 1 Department of Emergency and Intensive Therapy - University Hospital of Verona, VERONA, Italy, 2 Postgraduate School of Emergency Medicine - University of Verona, VERONA, Italy, 3 Department of Cardiology - Hospital University of Verona, VERONA, Italy, 4 Department of Internal Medicine and Postgraduate School of Medicine - University of Verona, VERONA, Italy

13-24 Abstract 15-54 QUANTIFICATION OF THE RELATIONSHIP BETWEEN LATE-GADOLINIUM INTENSITY AND CONDUCTION VELOCITY IN THE LEFT ATRIUM Rheeda L Ali 1, Norman A Qureshi 1, Chris D Cantwell 1, Caroline H Roney 1, Phang Boon Lim 1, Jennifer H Siggers 1, Spencer J Sherwin 1, Nicholas S Peter 1 1 Imperial College London, London, United Kingdom

13-25 Abstract 15-52 THE RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH ATRIAL

22

FIBRILLATION AFTER ELECTRICAL CARDIOVERSION Olga Litunenko 1, Oskars Kalejs 2, Aldis Strelnieks 1, Marina Kovalova 3, Iveta Sime 4, Milana Zabunova 2, Biruta Tilgale 5, Ilze Konrade 5, Evija Miglane 2, Kaspars Kupics 2, Irina Pupkevica 1, Aivars Lejnieks 5 1 Riga Stradins University, Riga, Latvia, 2 P.Stradins Clinical University Hospital, Riga, Latvia, 3 Jelgava Regional Hospital, Jelgava, Latvia, 4 Liepaja Regional Hospital, Liepaja, Latvia, 5 Riga East University Hospital, Riga, Latvia

13-26 Abstract 15-53 A NOVEL METHOD FOR ROTOR TRACKING USING BIPOLAR ELECTROGRAM PHASE TESTED ON SIMULATED, CELL CULTURE AND CLINICALLY ACQUIRED ELECTROGRAMS Caroline H Roney 1, Rasheda A Chowdhury 1, Chris D Cantwell 1, Norman A Qureshi 1, Emmanuel Dupont 1, Phang Boon Lim 1, Jennifer H Siggers 1, Fu Siong Ng 1, Nicholas S Peters 1 1 Imperial College London, London, United Kingdom

13-27 Abstract 15-48 RISK FACTORS OF RECURRENCE ATRIAL FIBRILLATION AFTER ELECTRICAL CARDIOVERSION Olga Litunenko 1, Aldis Strelnieks 2, Milana Zabunova 3, Kaspars Kupics 3, Kristine Jubele 3, Janis Pudulis 2, Sandis Sakne 3, Maija Vikmane 3, Marina Kovalova 4, Ilze Vinkalna 1, Aivars Lejnieks 2, Oskars Kalejs 3 1 Riga Stradins University, Riga, Latvia, 2 Riga East University Hospital, Riga, Latvia, 3 P.Stradins Clinical University Hospital, Riga, Latvia, 4 Jelgava Regional Hospital, Riga, Latvia

13-28 Abstract 15-47 ADDITION OF ATRIAL ECTOPY AND NT-PROBNP TO FRAMINGHAM ATRIAL FIBRILLATION RISK ALGORITHM IMPROVES RISK PREDICTION Preman Kumarathurai 1, Mette Mouridsen 1, Nick Mattsson 1, Bjørn Larsen 1, Olav Nielsen 1, Thomas Gerds 2, Ahmad Sajadieh 1 1 University Hosptial of Bispebjerg, Copenhagen, Denmark, 2 Department of Biostatistics, Copenhagen University, Copenhagen, Denmark

13-29 Abstract 15-43 BALLON MITRAL VALVULOTOMY FOR PATIENTS WITH MITRAL STENOSIS IN ATRIAL FIBRILATION : IMMEDIATE AND LONG TERM PROGNOSIS Marouane Mahjoub 1, Majed Hassine 1, Ghassan Cheniti 1, Ibtihel Mechri 1, Majdi Ben Massaoud 1, Zohra Dridi 1, Fethi Betbout 1, Habib Gamra 1 1 Cardiology department A : Fattouma Bourguiba University Hospital, Monastir, Tunisie

13-30 Abstract 15-42 SURFACE ECG IDENTIFICATION OF PERSISTENT AF DRIVER ACTIVITY DETECTED BY NONINVASIVE ELECTROCARDIOGRAPHIC IMAGING Torsten Konrad 1, Sebastien Knecht 2, Isabel Deisenhofer 3, Thomas Arentz 4, Mattias Duytschaever 5, Thomas Neumann 6, Bruno Cauchemez 7, Jean-Paul Albenque 8, Thomas Münzel 9, Cathrin Theis 1, Thomas Rostock 1 1 II. Med. Clinic, Department for Electrophysiology, Johannes Gutenberg-University, Mainz, Germany, 2 CHU Brugmann, Brussels, Belgium, 3 Dept. of Electrophysiology, Deutsches Herzzentrum München, Technische Universität, Munich, Germany, 4 Universitäts-Herzzentrum Freiburg-Bad Krozingen, , Bad Kronzingen, Germany, 5 Univ Hospital Ghent, Ghent, Belgium, 6 Kerckhoff Heart Center, Bad Nauheim, Germany, 7 Clinique Ambroise Paré, Neuilly-sur-Seine, France, 8 Clinique Pasteur, Toulouse, France, 9 II. Med. Clinic, Johannes Gutenberg-University, Mainz, Germany

23

SUNDAY APRIL 19, 2015 Luncheon Panel 12:15pm-1:45pm ROOM DUFY Seated Luncheon Panel 1 Supported by Boehringer Ingelheim

NOACs - What's new? Chairpersons: Samuel Lévy (Marseille, FR), Riccardo Cappato (Milan, IT)

1. Is data coming from clinical practice confirming the pivotal trials? How does it impact our decisions? Jean-Yves Le Heuzey (Paris, FR)

2. Optimal peri-procedural anticoagulation strategy in AF ablation: the search for new

evidence. Richard Schilling (London, GB)

3. Reversal agents for the NOACs: how are we going to use them?

Peter Verhamme (Leuven, BE)

SUNDAY APRIL 19, 2015 2:00 PM - 3:30 PM ROOM DERAIN Session AB-01

Pulmonary vein isolation and related strategies Chairpersons: Douglas Packer (Rochester, USA), Wyn Davies (London, GB) 1. AF mechanisms and role of pulmonary veins in various AF presentations

Karl-Heinz Kuck (Hamburg, DE)

2. Periprocedural dormant conduction after PV isolation: how does it affect AF recurrence? Heidi Estner (Munich, DE)

3. Do catheter techniques make a difference in success rates?

Leonardo Calo (Rome, IT) 4. Role of autonomic ganglia in AF ablation success rates

Yusuke Kondo (Chiba, JP)

SUNDAY APRIL 19, 2015 2:00 PM - 3:30 PM

24

ROOM DIDEROT Session HD-01

Update on inherited potentially lethal syndromes

Chairpersons: Peter Schwartz (Pavia, IT), Hugh Calkins (Baltimore, USA) 1. Long QT syndrome

Peter Schwartz (Pavia, IT)

2. Cathecholaminergic polymorphic VT Jacob Tfelt-Hansen (Copenhagen, DK)

3. Brugada syndrome

Herve Le Marec (Nantes, FR) 4. Early repolarization syndrome

Juhani Junttila (Oulu, FI)

SUNDAY APRIL 19, 2015 2:00 PM - 3:30 PM ROOM DESCARTES Session SP-07

Joint session of ECAS-WSA (World Society of Arrhythmology)

The new frontiers in cardiac pacing Chairpersons: Massimo Santini (Rome, DE), Eli Ovsyshcher (Beer Sheba, IL) 1. 50 years of cardiac pacing: where are we now?

João Rodrigues de Sousa (Lisbon, PT) 2. The leadless pacemaker

Antonio Curnis (Brescia, IT) 3. Multipoint pacing to optimize CRT outcome

Antonello Vado (Cuneo, IT) 4. Remote control: from device to patient management

Xavier Viñolas (Barcelona, ES)

5. Advances in biological pacing Gerard Boink (Amsterdam, NL)

SUNDAY APRIL 19, 2015 2:00 PM - 3:30 PM ROOM PASCAL Session SP-02

Prevention of sudden cardiac death in heart disease

25

Chairpersons: David Cannom (Los Angeles, USA), Poul Erik Bloch-Thomsen (Copenhagen, DK)

1. Effectiveness of Automatic External Defibrillators: availability and

employability Alessandro Capucci (Ancona, IT)

2. Indications and effectiveness of wearable ICDs

Johannes Brachmann (Coburg, DE)

3. What have we learned from prophylactic ICD trials? Robert Myerburg (Miami, USA)

4. What have we learned from ICD registries? Robert Hauser (Minneapolis, USA)

SUNDAY APRIL 19, 2015 2:00 PM - 3:30 PM ROOM GAUGUIN Chaired Poster session B part 1 Posters exposed from 2:00 PM - 5:00 PM Presenters and chairpersons present from 2:00 PM - 3:30 PM

Arrhythmias and heart disease

Chairpersons: Jacques Clementy (Bordeaux, FR), Claude Barnay (Aix en Provence, FR) 14-1 Abstract 17-15 VENTRICULAR TACHYARRHYTHMIA IN PATIENTS WITH CONGENITAL HEART DIS-EASE: WAIT-AND-SEE OR PREDICTABLE? Christophe Teuwen 1, Tanwier Ramdjan 1, Joris Vriend 2, Marco Gotte 2, Sander Molhoek 3, Reinhart Dorman 4, Jurren van Opstal 4, Thelma Konings 5, Pepijn van der Voort 6, Etienne Delacretaz 7, Ameeta Yaksh 1, Nienke Wolfhagen 1, Peter de Klerk 1, Dominic Theuns 1, Maarten Witsenburg 1, Jolien Roos-Hesselink 1, Paul Knops 1, Eva Lanters 1, John Tried-man 8, Ad Bogers 1, Natasja de Groot 1 1 Erasmus Medical Centre, Rotterdam, Netherlands, 2 Haga Hospital, The Hague, Nether-lands, 3 Amphia Hospital, Breda, Netherlands, 4 Medisch Spectrum Twente, Enschede, Netherlands, 5 VU University Medical Centre, Amsterdam, Netherlands, 6 Catharina Hospi-tal, Eindhoven, Netherlands, 7 Inselspital, University of Bern, Bern, Switzerland, 8 Boston Children's Hospital, Harvard Medical School, Boston, United States 14-2 Abstract 15-49 SIGNIFICANT DIFFERENCES IN PRESENTATION OF ATRIAL FIBRILLATION IN PATIENTS WITH STEMI AND NON-STEMI BUT SIMILAR ALL-CAUSE MORTALITY RISK AT 30 DAYS. Dritan Poci 1, Marianne Hartford 2, Thomas Karlsson 2, Kenneth Caidahl 3, Nils Edvardsson 2 1 Department of Cardiology, Univ. Hospital Örebro, Örebro, Sweden, 2 Institute of Medicine, Department of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, University of Gothenburg, , Gothenburg, Sweden, 3 Department of Molecular Medicine and Surgery, Karolinska Institutet, , Stockholm, Sweden

26

14-3 Abstract 07-17 INCIDENCES OF DYSRHYTHMIA IN THE OPERATING ROOM IN CHILDREN AFTER SURGERY FOR CONGENITAL HEART DISEASE Charlotte Houck 1, Ameeta Yaksh 1, Eva Lanters 1, Lisette van der Does 1, Christophe Teuwen 1, Maarten Witsenburg 1, Jolien Roos-Hesselink 1, Ad Bogers 1, Natasja de Groot 1 1 Erasmus Medical Center, Rotterdam, Netherlands

14-4 Abstract 14-12 DO ECTOPIC SUPRAVENTRICULAR PREMATURE BEATS PREDICT EARLY NEW-ONSET ATRIAL FIBRILLATION AFTER CORONARY ARTERY BYPASS SURGERY? Ameeta Yaksh 1, Charles Kik 1, Eva A.H. Lanters 1, Upaashna Chigharoe 1, Paul Knops 1, Maarten J.B. Van Ettinger 1, Marcel C.J. De Wijs 1, Peter Van de Kemp 2, Jan Hofland 1, Ad J.J.C. Bogers 1, Natasja N.M. De Groot 1 1 Erasmus MC, Rotterdam, Netherlands, 2 Sorin, Rotterdam, Netherlands

14-5 Abstract 15-55 PERIOPERATIVE INDUCIBILITY OF AF: PREDICTOR FOR DEVELOPMENT OF EARLY POSTOPERATIVE AF? Eva Lanters 1, Ameeta Yaksh 1, Lisette van der Does 1, Christophe Teuwen 1, Paul Knops 1, Charles Kik 1, Ad Bogers 1, Natasja de Groot 1 1 Erasmus MC, Rotterdam, Netherlands

14-6 Abstract 17-12 EARLY VENTRICULAR TACHYARRHYTHMIAS AFTER CORONARY ARTERY BYPASS GRAFTING SURGERY: IS IT A REAL BURDEN? Elisabeth Mouws 1, Ameeta Yaksh 1, Paul Knops 1, Charles Kik 1, M.J.B. van Ettinger 1, M. de Wijs 1, P. van de Kemp 2, Eric Boersma 1, Ad Bogers 1, Natasja de Groot 1 1 Erasmus Medical Center, Rotterdam, Netherlands, 2 Sorin Group, Amsterdam, Netherlands

14-7 Abstract 08-14 SYMPTOMATIC HIGH DEGREE HEART BLOCK COMPLICATING SYSTEMIC SARCOIDOSIS Malka Yahalom 1, Ofir Koren 2, Yoav Turgeman 1 1 Cardiolog Department, Ha’Emek Medical Center, Afula, Israel, 2 Internal Medicine C, Ha’Emek Medical Center, Afula, Israel

Techniques and tools

14-9 Abstract 18-13 PHYSICS OF RADIOFREQUENCY ABLATION IN-VITRO TEACHING SYSTEM FOR PHYSICIANS AND MEDICAL ENGINEERING STUDENTS Tobias Haber 1, Gennadie Kleister 1, Burcu Selman 1, Johannes Härtig 2, Juraj Melichercik 2, Bruno Ismer 1 1 Peter Osypka Institute for Pacing and Ablation, Offenburg, Germany, 2 MediClin Heart Center Lahr/Baden, Lahr, Germany

14-10 Abstract 04-11 IMPAIRED ADAPTATION OF WHOLE HEART ACTION POTENTIAL DURATION IN RESPONSE TO PHYSIOLOGICAL AUTONOMIC STRESS IN BRUGADA SYNDROME. Kevin Ming Wei Leong 1, Fu Siong Ng 1, Caroline Roney 1, Phang Boon Lim 1, Sian E Harding 1, Nicholas S Peters 1, Amanda Varnava 1, Prapa Kanagaratnam 1 1 NHLI, Imperial College London, London, United Kingdom

27

14-11 Abstract 03-10 LACK OF ATORVASTATIN PROTECTIVE EFFECT AGAINST ATRIAL FIBRILLATION IN B2B2 CETP GENOTYPE Francesca Galati 1, Antonio Galati 2, Serafina Massari 1 1 DiSTeBA, University of Salento, Lecce, Italy, 2 Division of Cardiology, Card. G. Panico Hospital, Tricase, Italy

14-12 Abstract 04-12 WHOLE HEART ACTIVATION PATTERNS DURING PHYSIOLOGICAL STRESS IN BRUGADA SYNDROME. Kevin Ming Wei Leong 1, Fu Siong Ng 1, Caroline Roney 1, Phang Boon Lim 1, Sian E Harding 1, Nicholas S Peters 1, Amanda Varnava 1, Prapa Kanagaratnam 1 1 NHLI, Imperial College London, London, United Kingdom

14-13 Abstract 04-14 ELECTROPHYSIOLOGICAL RESPONSES TO AUTONOMIC STIMULATION ARE BLUNTED IN A MURINE MODEL OF BRUGADA SYNDROME Malcolm Finlay 1, Vishal Vyas 2, Alistair Yeoh 1, Stephen Harmer 3, Christopher Huang 4, Pier Lambiase 5, Andrew Tinker 3 1 Barts Health NHS Trust and QMUL, London, United Kingdom, 2 UCL and QMUL, London, United Kingdom, 3 Queen Mary University of London, London, United Kingdom, 4 Cambridge University, Cambridge, United Kingdom, 5 UCL, London, United Kingdom

14-14 Abstract 05-12 THE LASER DOPPLER VIBROMETRY: A NON-CONTACT TECHNIQUE FOR HEART RHYTHM MONITORING Armin Luik 1, Laura Mignanelli 2, Kristian Kroschel 3, Claus Schmitt 1, Lorenzo Scalise 2, Christian Rembe 4 1 Staedtisches Klinikum Karlsruhe, Karlsruhe, Germany, 2 Università Politecnica delle Marche, Ancona, Italy, 3 Fraunhofer Institut IOSB, Karlsruhe, Germany, 4 Polytech, Waldbronn, Germany

14-15 Abstract 05-14 SENSITIVITY OF OPTICAL MAPPING PHASE DYNAMICS TO POST-PROCESSING PARAMETERS INCLUDING LOW-PASS FILTER CUT-OFF FREQUENCY AND SPATIAL BINNING Caroline H Roney 1, Chris D Cantwell 1, Michael T Debney 1, Norman A Qureshi 1, Prapa Kanagaratnam 1, Jennifer H Siggers 1, Nicholas S Peters 1, Fu Siong Ng 1 1 Imperial College London, London, United Kingdom

14-16 Abstract 28-10 FIRST APPLICATION OF A NOVEL, MULTI-SITE, HIGH-RESOLUTION EPICARDIAL, MAPPING APPROACH Natasja de Groot 1, Ameeta Yaksh 1, Charles Kik 1, Paul Knops 1, Frans Oei 1, Pieter van de Woestijne 1, Maurits Allessie 1, Ad Bogers 1 1 Erasmus Medical Center, Rotterdam, Netherlands

3:30 PM - 4:00 PM Coffee break and Posters

SUNDAY APRIL 19, 2015 4:00 PM - 5:30 PM ROOM DERAIN Session AB-02

28

Issues in ventricular tachycardia ablation (I)

Chairpersons: Nicholas Peters (London, GB), Jasbir Sra (Milwaukee, USA) 1. New insights into the VT substrate using the Rhythmia System Elad Anter (Boston, USA) 2. Functional characterization of VT scar by Ripple Mapping

Prapa Kanagaratnam (London, GB) 3. Epicardial ablation of VT

Katja Zeppenfeld (Leiden, NL) 4. Ablation of bundle branch and fascicular ventricular tachycardia

Jasbir Sra (Milwaukee, USA)

SUNDAY APRIL 19, 2015 4:00 PM - 5:30 PM ROOM DIDEROT Session SP-03

The MADIT (Multicenter Automatic Defibrillator Implantation) Trials

Chairpersons: David Cannom (Los Angeles, USA), Luigi Padeletti (Florence, IT) 1. Long-term prognosis of MADIT-CRT patients: new data

Mark Estes III (Boston, USA) 2. MADIT-CHAGAS study: design and early data

Claudio Schuger (Detroit, USA) 3. MADIT-CHIC study: design and early data

Jagmeet P. Singh, (Boston, USA) 4. Importance of LBBB in predicting a positive response to CRT therapy in Class

I/II heart failure David S. Cannom (Los Angeles, USA)

5. Impact of Type II diabetes on the prognosis of coronary patients with heart

failure: what would an ICD trial look like in this patient group? Helmut Klein (Munich, DE)

SUNDAY APRIL 19, 2015 4:00 PM - 5:30 PM Room DESCARTES Session SP-04

Advances in Intracardiac Imaging for Interventional Electrophysiologists: 2015 and beyond

Chairpersons: Andrea Natale (Austin, USA), Roger Winkle (Palo Alto, USA)

29

1. Cardiac CT for definition of left atrial appendage morphology and risk stratification

Luigi Di Biase (New York, USA) 2. Intracardiac echocardiography performed from and for the pulmonary

vasculature - technique and application Sanjeev Saksena (Warren, USA)

3. Magnetic resonance imaging of the atrial substrate and progression of atrial

fibrillation: a critical analysis Mark O’Neill (London, GB) 4. Real time three dimensional imaging of cardiac chambers Mohammad Shenasa (San Jose, USA)

SUNDAY APRIL 19, 2015 4:00 PM - 5:30 PM Room PASCAL Session SP-05

Stroke prevention in atrial fibrillation

Chairpersons: John Camm (London, GB), Johannes Brachmann (Coburg, DE) 1. NOACs- 5 years after RE-LY: What have we learned?

Michael Näbauer (Munich, DE)

2. Interventional therapy by occluder devices – which patients should be considered? Thorsten Lewalter (Munich DE)

3. Ablation therapy for stroke prevention in patients with AF

John Fisher (New York, USA)

4. Role of continuous rhythm monitoring - identification of cause or bystander? Albert Waldo (Cleveland, USA)

SUNDAY APRIL 19, 2015 3:30 PM - 5:00 PM ROOM GAUGUIN Chaired poster session B part 2 Posters exposed from 2:00 PM - 5:00 PM Presenters and chairpersons present from 3:30 PM - 5:00 PM Chairpersons: Bharat Kantharia (Houston, USA), Francisco Furlanello (Milan, IT)

Atrial fibrillation ablation 14-17 Abstract 15-39 SIMULTANEOUS PULMONARY VEIN CRYOABLATION AND CAVOTRICUSPID ISTH-MUS RADIOFREQUENCY ABLATION IN PATIENTS WITH COMBINED ATRIAL FIBRIL-LATION AND TYPICAL ATRIAL FLUTTER Michael Peyrol 1, Pascal Sbragia 1, Thibault Ronchard 1, Jennifer Cautela 1, Chloé Vil-

30

lacampa 1, Marc Laine 1, Laurent Bonello 1, Franck Thuny 1, Franck Paganelli 1, Samuel Lévy 2 1 CHU Nord, Marseille, France, 2 Aix-Marseille Université, Marseille, France 14-18 Abstract 15-30 FEASIBILITY AND SAFETY OF NURSE-DIRECTED DEEP SEDATION Laura Varotto 1, Mehdi Namdar 1, François Mattey-Prévot 1, Jacques Lyvet 1, Dominique Marcelot 1, Alain-Stéphane Eichenberger 1, Pascale Gentil-Baron 1, Henri Sunthorn 1, Haran Burri 1, Dipen Shah 1 1 Hôpitaux Universitaires de Genève, Service de Cardiologie, Geneva, Switzerland, Geneva, Switzerland

14-19 Abstract 15-31 MINIMALLY INVASIVE SURGICAL ABLATION FOR STAND-ALONE ATRIAL FIBRILLATION IS ASSOCIATED WITH EXCELLENT OUTCOMES AT LONG TERM FOLLOW-UP Gianluigi Bisleri 1, Fabrizio Rosati 1, Lorenzo Di Bacco 1, Claudio Muneretto 1 1 University of Brescia Medica School, Brescia, Italy

14-20 Abstract 15-14 TIME COURSE OF LUMINAL ESOPHAGEAL TEMPERATURE DURING SECOND-GENERATION CRYOBALLOON ABLATION: COMPARISON OF THE 23MM AND 28MM BALLOON Benedikt Bunz 1, Florian Straube 1, Uwe Dorwarth 1, Martin Schmidt 1, Michael Wankerl 1, Stephen Howard 2, Stefan Hartl 1, Hans Ullrich Ebersberger 1, Ellen Hoffmann 1 1 Department of Cardiology and Internal Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich Municipal Hospital Group, Munich, Germany, 2 Medtronic Inc., Mounds View, MN, United States

14-22 Abstract 18-24 ASSESSMENT OF BMI AND HEMODYNAMIC PARAMETERS IN AF PATIENTS UN-DERGOING PULMONARY VEIN ISOLATION PROCEDURES – POTENTIAL IMPACT ON PROCEDURAL PARAMETERS AND AF RECURRENCE Johannes Siebermair 1, Stefan Sattler 1, Eva Klocker 1, Lucia Olesch 1, Samira Saraj 1, Ina Klier 1, Christoph Schuhmann 1, Sebastian Clauss 1, Moritz Sinner 1, Stefanie Fichtner 1, Stefan Kääb 1, Heidi L. Estner 1, Reza Wakili 1 1 Medical Department I, KlinikumGrosshadern Munich, University of Munich, Munich, Ger-many 14-23 Abstract 18-15 LONG-TERM EFFICACY OF PULMONARY VEIN ANTRUM ISOLATION ALONE IN ATRIAL FIBRILLATION ABLATION, A SINGLE CENTER COHORT STUDY. Cas Teunissen 1, Jeroen vd Heijden 1, Rutger Hassink 1, Wil Kassenberg 1, Rolf Brummel 1, Peter Loh 1 1 Utrecht Medical Center Utrecht, Utrecht, Netherlands

14-24 Abstract 18-18 SAFETY OF THE 56-HOLE OPEN IRRIGATION ABLATION CATHETER IN PULMONA-RY VEIN ISOLATION FOR ATRIAL ABLATION Wahaj Aman 1, Mohamed Bassiouny 1, Ayman Hussein 1, John Rickard 2, Khaldoun Tarakji 1, Bryan Baranowski 1, Thomas Callahan 1, Mandeep Bhargava 1, Thomas Dresing 1, Mo-hamed Kanj 1, Patrick Tchou 1, Bruce Lindsay 1, Walid Saliba 1, Oussama Wazni 1 1 Cleveland Clinic, Cleveland, United States, 2 John Hopkins, Baltimore, United States 14-25 Abstract 15-35 CLINICAL 1 YEAR EXPERIENCE WITH A NOVEL MULTIPOLAR IRRIGATED

31

ABLATION CATHETER IN AF ABLATION PROCEDURES Reza Wakili 1, Johannes Siebermair 1, Eva Klocker 1, Stephanie FIchtner 1, Stefan Sattler 1, Moritz F. Sinner 1, Lucia Olesch 1, Samira Saraj 1, Christoph Schuhmann 1, Stefan Kääb 1, Heidi Estner 1 1 Medizinische Klinik und Poliklinik I, Grosshadern Clinic, University of Munich, Munich, Germany

14-26 Abstract 28-19 EARLY CLINICAL EXPERIENCE WITH THE RHYTHMIA 3D MAPPING SYSTEM: RAPID, AUTOMATIC, ACCURATE, HIGH DENSITY MAPPING OF COMPLEX ARRHYTHMIAS FACILITATES SUCCESSFUL ABLATION Markus Sikkel 1, Vishal Luther 2, James Harrison 1, Louisa Malcolm-Lawes 1, Sajad Hayat 1, Fu-Siong Ng 2, Ian Wright 1, Norman Qureshi 2, Kevin Leong 2, Nicholas Linton 1, Michael Koa-WIng 1, David Lefroy 1, Phang Boon Lim 1, Zachary Whinnett 2, Nicholas Peters 2, Prappa Kanagaratnam 1, D Wyn Davies 1 1 Imperial NHS Healthcare Trust, London, United Kingdom, 2 Imperial College, London, United Kingdom

14-27 Abstract 28-18 DOES ATRIAL FIBRILLATION ORGANIZE SPATIALLY OR TEMPORALLY BEFORE TERMINATION? CONTINUOUS TRACKING OF SPATIO-TEMPORAL PERIODICITY DURING ABLATION Junaid Zaman 1, Rishi Trikha 1, Tina Baykaner 2, David Krummen 2, Paul Wang 1, Wouter-Jan Rappel 2, Sanjiv Narayan 1 1 Stanford University, Stanford, United States, 2 University of California, San Diego, San Diego, United States

14-28 Abstract 01-20 MIGHT CARDIOVERSION BE THE END-POINT FOR RADIOFREQUENCY ABLATION OF LONG-LASTING PERSISTENT ATRIAL FIBRILLATION PATIENTS: EXTRAPOLATION OF MATHEMATICAL MODELING DATA TO CLINICAL RESULTS OF ABLATION Andrey Ardashev 1, Mikhail Mazurov 2, Yury Belenkov 3, Ilia Kolodyazhny 2, Vasily Finko 1, Evgeny Zhelyakov 1 1 Federal Scientific and Clinical Centre of FMBA, Moscow, Russia, 2 Moscow University of Economic, Statistic and Informatic, Moscow, Russia, 3 Lomonosov State University, Moscow, Russia

14-29 Abstract 05-13 THE IMPACT OF CATHETER CONTACT FORCE ON HUMAN LEFT ATRIAL ELECTROGRAM CHARACTERISTICS IN SINUS RHYTHM AND ATRIAL FIBRILLATION Waqas Ullah 1, Ross Hunter 1, Baker Victoria 1, Liang-han Ling 2, Mehul Dhinoja 1, Simon Sporton 1, Mark Earley 1, Richard Schilling 1 1 St Bartholomew's Hospital, London, United Kingdom, 2 Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Australia

14-30 Abstract 15-56 RADIOFREQUENCY ATRIAL FIBRILLATION ABLATION USING 3D MAPPING SYSTEM NAVIGATION: FIRST SINGLE-CENTRE EXPERIENCE IN NORTH AFRICA. Sonia Marrakchi 1, Azima Ben Tanfous 1, Bechir Zouari 2, Abdelatif Lefi 1, Hend Keskes 1, Afef Ben Halima 1, Faouzi Added 1, Ikram Kammoun 1, Salem Kachboura 1 1 Abderrahmane Mami Hospital, Tunis, Tunisie, 2 Tunis Medical University, Tunis, Tunisia

Screening athletes

32

14-31 Abstract 07-16 ELECTROCARDIOGRAPHIC AND ECHOCARDIOGRAPHIC EVALUATION OF A LARGE COHORT OF YOUNG SOCCER PLAYER’S DURING PRE-PARTICIPATION SCREENING. Annamaria Martino 1, Fabio Sperandii 1, Emanuele Guerra 1, Elena Cavarretta 2, Federico Quaranta 3, Attilio Parisi 3, Antonia Nigro 2, Luigi Sciarra 1, Ermenegildo de Ruvo 1, Antonio Spataro 4, Fabio Pigozzi 3, Leonardo Calo' 1 1 Cardiology Department, Policlinic Casilino, Rome, Italy, 2 FMSI Sport Medicine Institute, Villa Stuart Sport Clinic-FIFA Centre of Excellence and Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University, Rome, Italy, 3 Department of Health Sciences, University of Rome “Foro Italico”, , Rome, Italy, 4 Institute of Sports Medicine and Science (CONI), Rome, Italy

SUNDAY APRIL 19, 2015 Room DERAIN 5:30 PM to 6:00 PM

Special lecture: A tribute to Philippe Coumel

“The story behind the discovery of entrainment”

By Albert Waldo (Cleveland, USA)

6:00 PM-7:00PM

Opening ceremony

Prof. Samuel Lévy (Marseille, FR), Prof. Gerhard Steinbeck (Munich, DE), Prof. Nicolas Lellouche (Paris, FR), Prof. Xavier Jouven (Paris, FR), Dr Riccardo Cappato (Milan, IT)

Outstanding Achievement Awards

Presented by Dr Riccardo Cappato (Milan, IT) President of ECAS Prof. Nicolas Lellouche (Paris, FR) Congress Chairman Dr Fernand Hessel (Mulhouse, FR) President Lucien Dreyfus Foundation

Best Abstracts Awards

33

Followed by a cocktail Reception

MONDAY APRIL 20, 2015 08:30 AM - 10:00 AM ROOM COROT Session SP-06

Atrial Fibrillation: Beyond Stroke Prevention Chairpersons: Nils Edvardsson (Gothenburg, SE), Amiran Revishvili (Moscow, RU)

1. Cardiovascular Morbidity and Mortality of AF Christine Albert (Boston, USA)

2. Atrial Fibrillation and Sudden Cardiac Death

Eloi Marijon (Paris, FR) 3. Role of Pharmacology

Juan Tamargo (Madrid, ES) 4. Role of Catheter Ablation

Walid Saliba (Cleveland, USA)

MONDAY APRIL 20, 2015 08:30 AM - 10:00 AM ROOM DIDEROT Session SP-07

Sudden cardiac death: Focus on at risk patients with secondary left ventricular hypertrophy (LVH) Chairpersons: John Fisher (New-York, USA), Dubravko Petrac (Zagreb, HR)

1- ECG and MRI criteria of LVH James Harrison (London, GB)

2- Mechanism of ventricular arrhythmias in patients with LVH

Nabil El-Sherif (New-York, USA) 3- Risk stratification of patients with LVH at risk of sudden cardiac death

Gerhard Steinbeck (Munich, DE) 4- Regression of LVH and clinical outcomes

Ariel Cohen (Paris, FR)

MONDAY APRIL 20, 2015 08:30 AM - 10:00 AM ROOM DESCARTES Session HD-03

HRS-ECAS SPECIAL SESSION I Arrhythmogenic Cardiomyopathy I

34

Diagnosis and Mechanisms

Chairpersons: Peter Van Tintelen (Amsterdam, NL), Connie Bezzina (Amsterdam, NL) 1. History of the disease

Guy Fontaine (Paris, Fr) 2. Advantages/ limitations of the Revised Task Force Criteria

Richard Hauer (Utrecht NL) 3. Pathogenicity of genetic variants

Dennis Dooijes (Utrecht, NL) 4. Role of substructures in the Intercalated disk

Mario Delmar (New York, USA)

MONDAY APRIL 20, 2015 08:30 AM - 10:00 AM ROOM PASCAL Session AB-03

Highly technologic approach in catheter ablation of complex arrhythmias

Chairpersons: Richard Schilling (London), Andrey Ardashev (Moscow, RU)

1. 3-D mapping and contact force sensing in ablation of atrial fibrillation Roberto De Ponti, (Varese, IT)

2. Remote navigation ablation of atrial fibrillation and flutter using remote

manipulation of multiple catheters Eugene Crystal (Toronto, CA)

3. Preprocedural imaging and 3-D mapping in patients with ventricular

tachycardia associated with structural heart disease Richard Schilling (London, GB)

4. 3-D mapping and contact force sensing in ablation of idiopathic ventricular

tachycardia David Wilber (Chicago, USA)

MONDAY APRIL 20, 2015 08:30 AM - 10:30 AM ROOM GAUGUIN Chaired Poster session C Part 1 Posters exposed from 8:30 AM - 12:00 PM Presenters and chairpersons present from 09:00 AM - 10:30 AM

Cardiac resynchronization therapy Chairpersons: Bruce Wilkoff (Cleveland, USA), Werner Jung (Villingen, DE)

35

15-1 Abstract 24-26 CARDIAC RESYNCHRONIZATION THERAPY: LEFT VENTRICULAR LEAD PLACE-MENT GUIDED BY CORONARY VENOUS ELECTROANATOMIC MAPPING Massimiliano Maines 1, Carlo Angheben 1, Massimiliano Marini 2, Alessio Coser 2, Domeni-co Catanzariti 1, Maurizio Del Greco 1 1 Santa Maria del Carmine Hospital, Rovereto, Italy, 2 Santa Chiara Hospital, Trento, Italy 15-2 Abstract 24-11 ACUTE HEMODYNAMIC MEASUREMENTS AND CONTACT ACTIVATION MAPPING DURING MULTIPOINT LEFT VENTRICULAR PACING Antonello Vado 1, Endrj Menardi 1, Ballari Gian Paolo 1, Guido Rossetti 1 1 Ospedale S.Croce e Carle, Cuneo, Italy

15-3 Abstract 24-12 COMPARISON BETWEEN NEUROHORMONAL PROFILE AFTER IMPLANT OF BIVENTRICULAR ICD AND PROFILE AFTER BIVENTRICULAR ICD WITH MULTIPOLAR PACING IN PATIENTS WITH HEART FAILURE Domenico Spaziani 1, Laura Striuli 1, Roberto Turato 1, Pasquale Gangitano 1, Maurizio D'Urbano 1, Guido Grassi 2 1 Ospedale Fornaroli, Magenta, Italy, 2 Università Milano-Bicocca, Milano, Italy

15-4 Abstract 24-16 DISTRIBUTION OF ESOPHAGEAL INTERVENTRICULAR CONDUCTION DELAYS IN CRT PATIENTS AND HEALTHY SUBJECTS Johannes Härtig 1, Anna Nagel 2, Kirsten Rotter 2, Tobias Haber 2, Laura Perez Escobar 2, Juraj Melichercik 1, Bruno Ismer 2 1 MediClin Heart Center Lahr/Baden, Lahr, Germany, 2 Peter Osypka Institute for Pacing and Ablation, Offenburg, Germany

15-5 Abstract 24-18 RIGHT VENTRICULAR SEPTAL PACING IN PATIENTS WITH RIGHT BUNDLE BRANCH BLOCK, ELECTRO- AND ECHO-CARDIOGRAPHIC OUTCOMES Belal Al Khiami 1, Basil Abu-El-Haija 1, Omer Iqbal 1, Paul Lindower 1, Michael Giudici 1 1 University of Iowa Hospitals and Clinics , Iowa City , United States

15-6 Abstract 24-22 PATIENTS WITH LEFT BUNDLE BRANCH BLOCK AND LEFT AXIS DEVIATION SHOW A SPECIFIC LEFT VENTRICULAR ASYNCHRONY PATTERN: POSSIBLE IMPLICATIONS FOR LEFT VENTRICULAR LEAD PLACEMENT DURING CRT IMPLANTATION Luigi Sciarra 1, Paolo Golia 2, Monia Minati 1, Ermenegildo De Ruvo 1, Antonio Scarà 1, Alessio Borrelli 1, Lucia De Luca 1, Chiara Lanzillo 1, Alessandro Fagagnini 1, Marco Rebecchi 1, Ludovica Scialla 1, Elisa Salustri 3, Domenico Grieco 1, Leonardo Calò 1 1 Cardiologia - Università La Sapienza, Rome, Italy, 2 Cardiologia - Ospedale di Forlì, Forlì, Italy, 3 Cardiologia - Università de L'Aquila, L'Aquila, Italy

15-7 Abstract 24-23 PROGNOSTIC VALUE OF EPICARDIAL-ENDOCARDIAL GRADIENT MEASURED BY ECHOCARDIOGRAPHY TO PREDICT CARDIAC RESYNCHRONIZATION THERAPY (CRT) RESPONSE Frederic Sebag 1, Nicolas Lellouche 1, Nicolas Mignot 1, Nathalie Elbaz 1 1 Departement de Cardiologie CHU Mondor, CRETEIL, France

15-8 Abstract 24-24 LARGE CAPACITY LIMNO2 BATTERIES EXTENDED CRTD LONGEVITY IN CLINICAL

36

USE COMPARED TO SMALLER CAPACITY LISVO BATTERIES OVER 6 YEARS Ernest Lau 1, Carol Wilson 1, Kyle Ashfield 1, Wilson McNair 1, David McEneaney 1, Michael Roberts 1 1 Royal Victoria Hospital, Belfast, United Kingdom

15-9 Abstract 24-27 ATRIAL REVERSE REMODELING AFTER CARDIAC RESYNCHRONIZATION THERAPY FOR HEART FAILURE Alaa Allah Al Anany 1, Said Khaled 1, Mazen Ibrahim 1, Mohamed Abdel Hameed 1, Ayman Abdel Motalib 1, John Zarif 1 1 Ain Shams University hospital, Cairo, Egypt

15-10 Abstract 31-11 EFFECT OF LEFT VENTRICULAR REMODELING ON ENDOCARDIAL SENSED R WAVE AMPLITUDES Omer Iqbal 1, Lee Joseph 1, Siva Krothapalli 1, Miriam Zimmerman 1, Michael Giudici 1, Kanu Chatterjee 1 1 University of Iowa hospitals and clinics, Iowa city , United States

Arrhythmia mechanisms

15-11 Abstract 02-15 TISSUE STRUCTURE FUNCTION RELATIONSHIPS - SIZE AND DIRECTION DO MATTER. Junaid Zaman 1, Sayed Al-Aidarous 1, Samha Alayoubi 1, Pravina Patel 1, Cesare Terracciano 1, Nicholas Peters 1 1 Imperial College London, London, United Kingdom

15-13 Abstract 19-19 ASSOCIATION OF TERC RELATED GENETIC VARIATION AND TELOMERASE ACTIVITY WITH VENTRICULAR ARRHYTHMIAS IN ISCHAEMIC CARDIOMYOPATHY Vinit Sawhney 1, Scott Brouilette 2, Niall Campbell 1, Steven Coppen 2, Victoria Baker 1, Claire Kirkby 1, Ross Hunter 1, Mehul Dhinoja 1, Mark Earley 1, Simon Sporton 1, Ken Suzuki 2, Richard Schilling 1 1 St Bartholomew's hospital, London, United Kingdom, 2 William Harvey Heart Centre, London, United Kingdom

15-14 Abstract 01-15 THE QT INTERVAL INCREASES WITH DECREASING PLASMA POTASSIUM IN THE DANISH GENERAL POPULATION Jorgen Kanters 1, Claus Graff 2, Jimmi Nielsen 2, Lise Henriksen 1, Anne Sofie Petri 1, Michael Christiansen 3, Jan Kvetny 4, Christina Ellervik 4 1 University of Copenhagen, Copenhagen N, Denmark, 2 Aalborg University, Aalborg, Denmark, 3 Statens Serum Institut, Copenhagen, Denmark, 4 Næstved Hospital, Næstved, Denmark

15-15 Abstract 04-10 LOCALISATION OF GANGLIONIC PLEXI SITES WITHIN THE LEFT ATRIUM Belinda Sandler 1, Nick Linton 1, Michael Koa Wing 1, Saj Hayet 1, Norman Qureshi 1, Vishal Luther 1, Nicholas Peters 1, Wyn Davies 1, Louisa Malcome Lawes 1, Boon Lim 1, Prapa Kanagaratnam 1 1 Imperial College London, London, United Kingdom

10:00 AM - 10:30 AM Coffee break and Posters

37

MONDAY APRIL 20, 2015 10:30 AM - 12:00 PM Concurrent Oral Abstract sessions ROOM COROT Abstract Oral Session 5

Advances in atrial fibrillation ablation II Chairpersons: Jasbir Sra (Milwaukee, USA), Brian Olshansky (Iowa City, USA) 5-1 Abstract 04-13 SITES OF ATRIAL FIBRILLATION ROTORS MAY OVERLAY GANGLIONATED PLEXI IN LEFT ATRIUM Tina Baykaner 1, Junaid Zaman 2, Theodoros Zografos 3, Ioannis Pantos 3, David Krummen 1, Demosthenes Katritsis 3, Sanjiv Narayan 4 1 University of California, San Diego, San Diego, United States, 2 Imperial College London, London, United Kingdom, 3 Athens Euroclinic, Athens, Greece, 4 Stanford University, Palo Alto, United States 5-2 Abstract 28-16 FEASIBILITY OF A NON-INVASIVE ELECTROCARDIOGRAPHIC MAPPING SYSTEM AT LOCALISATION OF ECTOPY TO GUIDE ABLATION IN PATIENTS UNDERGOING REPEAT CATHETER ABLATION FOR ATRIAL FIBRILLATION Norman Qureshi 1, Cheng Yao 2, Shahnaz Jamil-Copley 1, Michael Koa-Wing 1, Sajad Hayat 1, Fu Siong Ng 1, Afzal Sohaib 1, Elaine Lim 1, Ian Wright 1, Nick Linton 1, David Lefroy 1, Zachary Whinnett 1, Nicholas Peters 1, Prapa Kanagaratnam 1, Phang Boon Lim 1, D Wyn Davies 1 1 Imperial College, London, United Kingdom, 2 CardioInsight Technologies, Cleveland, OH, United States

5-3 Abstract 15-46 SIMILARITY OF SUBSTRATES IN PATIENTS WITH POST-ABLATION RECURRENT PAROXYSMAL ATRIAL FIBRILLATION VERSUS PERSISTENT ATRIAL FIBRILLATION: A 10-CENTER PROSPECTIVE STUDY Junaid Zaman 1, Vijay Swarup 2, Robert Kowal 3, James Daubert 4, John Day 5, John Hummel 6, David Krummen 7, Moussa Mansour 8, Vivek Reddy 9, Kevin Wheelan 3, Sanjiv Narayan 1, John Miller 10 1 Stanford University, Stanford, United States, 2 Arizona Heart Rhythm Center, Phoenix, United States, 3 Baylor University Medical Center, Dallas, United States, 4 Duke University Medical Center, Durham, United States, 5 Intermountain Medical Center, Salt Lake City, United States, 6 Ohio State University, Columbus, United States, 7 University of California, San Diego, San Diego, United States, 8 Massachusetts General Hospital, Boston, United States, 9 Mount Sinai School of Medicine, New York, United States, 10 Indiana University School of Medicine, Indianapolis, United States

5-4 Abstract 15-37 FEASIBILITY, SAFETY AND COSTS OF DAY CASE AF ABLATION Sarah Anderson 1, Conn Sugihara 1, Ragunath Shunmugam 1, Rick Veasy 1, Aerakondal Gopalamurugan 1, Steve Furniss 1, Neil Sulke 1 1 Cardiology Research Department, Eastbourne Hospital, East Sussex Healthcare NHS Trust, UK, Eastbourne, United Kingdom

38

5-5 Abstract 15-41 SAFETY AND EFFICACY OF PULMONARY VEIN ISOLATION USING A CIRCULAR, OPEN IRRIGATED MAPPING AND ABLATION CATHETER: A MULTI CENTER REGISTRY Ermenegildo de Ruvo 1, Massimo Grimaldi 2, Giovanni Rovaris 3, Ezio Soldati 4, Giuseppe Stabile 5, Matteo Anselmino 6, Francesco Solimene 7, Assunta Iuliano 5, Vincenzo Schillaci 6, Luigi Sciarra 1, Maria Grazia Bongiorni 4, Fiorenzo Gaita 6, Leonardo Calò 1 1 Policlinico Casilino ASL RM/B, Rome, Italy, 2 Ospedale Miulli, Acquaviva delle Fonti, Italy, 3 Osedale San Gerardo, Monza, Italy, 4 Azienda Ospedaliero Universitaria Pisana, Pisa, Italy, 5 Clinica Mediterranea, Napoli, Italy, 6 Dipartimento Scineze Mediche, Università di Torino, Torino, Italy, 7 Clinica Montevergine, Mercogliano, Italy

5-6 Abstract 15-40 SINGLE CENTRE EXPERIENCE AND OUTCOME OF PERSISTENT AF ABLATION USING THE NMARQ CATHETER: 2 YEAR FOLLOW-UP Shunmugam Ragunath Shunmugam 1, Rick Veasey 1, Conn Sugihara 1, Sarah Anderson 1, Aerakondal Gopalamurugan 1, Furniss Steve 1, Sulke Neil 1 1 East Sussex health care NHS trust, Eastbourne, United Kingdom

MONDAY APRIL 20, 2015 10:30 AM - 12:00 PM ROOM DIDEROT Abstract Oral Session 6

Cardiac resynchronization therapy: techniques and outcome Chairpersons: Pascal Defaye (Grenoble, FR), Nicolas Lellouche (Paris, FR)

6-1 Abstract 24-20 A HIGHLY EFFECTIVE TECHNIQUE FOR TRANSSEPTAL ENDOCARDIAL LEFT VEN-TRICULAR LEAD PLACEMENT FOR DELIVERY OF CARDIAC RESYNCHRONISATION THERAPY Giulia Domenichini 1, Ihab Diab 2, Niall Campbell 1, Mehul Dhinoja 1, Ross Hunter 1, Simon Sporton 1, Mark Earley 1, Richard Schilling 1 1 Department of Cardiology, St Bartholomew’s Hospital, London, United Kingdom, 2 The Bristol Heart Institute, University Hospital Bristol NHS Foundation Trust, Bristol, United Kingdom 6-3 Abstract 31-16 ATRIAL RESYNCHRONIZATION COMBINED WITH “BACKGROUND” ANTIARRHYTHMIC THERAPY IMPROVES SURVIVAL IN IN PATIENTS WITH ATRIAL FIBRILLATION AND HEART FAILURE WITH OR WITHOUT SYSTOLIC LEFT VENTRICULAR DYSFUNCTION Sanjeev Saksena 1, Marwan Saad 1, April Slee 1, Hansini Laharawani 1, Rangadham Nagarakanti 1 1 Electrophysiology Research Foundation, Warren, United States

6-5 Abstract 24-19 LONG- TERM FOLLOW- UP AFTER LEFT VENTRICULAR ENDOCARDIAL RESYNCHRONIZATION THERAPY: MORTALITY AND THROMBOEMBOLIC COMPLICATION ZSuzsanna KIS 1, Imre KASSAI M.D, PhD 1, Attila MIHALCZ M.D 1, Attila KARDOS M.D PhD 1, Csaba FOLDESI M.D 1, Andrea ARANY M.D 2, Gabriella GYORI M.D 2, Tamas

39

SZILI-TOROK M.D PhD 3 1 Gottsegen Gyorgy National Cardiology Institute, Budapest, Hungary, 2 United St. Istvan and Laszlo Hospital , Budapest, Hungary, 3 Erasmus University , Rotterdam , Netherlands

6-6 Abstract 24-13 NON ISCHEMIC CARDIOMYOPATHY AND LOW BURDEN OF SCAR AS REVEALED BY AN ECG-SCORE: NO NEED FOR A DEFIBRILLATOR IN SPECIAL PATIENTS AFTER CARDIAC RESYNCHRONISATION? Martin Grett 1, Hans-Joachim Trappe 1 1 Department of Cardiology and Angiology, University of Bochum, Bochum, Germany

MONDAY APRIL 20, 2015 10:30 AM - 12:00 PM ROOM DESCARTES Abstract Oral Session 7

Mapping and ablation of ventricular arrhythmias Chairpersons: Francis Marchlinski (Philadelphia, USA), Isabel Deisenhofer (Munich, DE) 7-1 Abstract 17-18 INTERMEDIATE TO LONG-TERM FOLLOW-UP OF IDIOPATHIC VENTRICULAR FI-BRILLATION ABLATION Cheryl Teres 1, Mehdi Namdar 1, Pascale Gentil-Baron 1, Henri Sunthorn 1, Haran Burri 1, Dipen Shah 1 1 Hôpitaux Universitaires de Genève, Service de Cardiologie, Geneva, Switzerland, Gene-va, Switzerland 7-3 Abstract 28-14 FEASIBILITY OF USING RIPPLE MAPPING TO IDENTIFY AND ABLATE CONDUCTION CHANNELS WITHIN THE VENTRICULAR SCAR Vishal Luther 1, Shahnaz Jamil-Copley 1, Nicholas Linton 1, Michael Koa-Wing 1, Sajad Hayat 1, Pasquale Vergara 2, Fu-Siong Ng 1, Zachary Whinnett 1, Phang Boon Lim 1, David Lefroy 1, David Wyn Davies 1, Nicholas Peters 1, Paolo Della Bella 2, Prapa Kanagaratnam 1 1 Imperial College Healthcare NHS Trust, London, United Kingdom, 2 San Raffaele Hospital, Milan, Italy

7-4 Abstract 18-19 NON-RANDOMISED COMPARISON OF ACUTE AND LONG TERM OUTCOMES OF ROBOTIC VERSUS MANUAL VENTRICULAR TACHYCARDIA ABLATION. Vishal Luther 1, Shahnaz Jamil-Copley 1, Michael Koa-Wing 1, Matthew ShunShin 1, Ian Wright 1, Sajad Hayat 1, Nicholas Linton 1, Phang Boon Lim 1, Zachary Whinnett 1, David Lefroy 1, Nicholas Peters 1, David Wyn Davies 1, Prapa Kanagaratnam 1 1 Imperial College Healthcare NHS Trust, London, United Kingdom 7-5 Abstract 17-14 CLINICAL EXPERIENCE USING A NEW FLUOROSCOPY-INTEGRATED CATHETER TRACKING SYSTEM (MEDIGUIDE) FOR ABLATION OF VENTRICULAR TACHYCARDIA - A CASE MATCHED COMPARISON Michael Derndorfer 1, Elisabeth Sigmund 1, Georgios Kollias 1, Siegmund Winter 1, Helmut Pürerfellner 1, Josef Aichinger 1, Martin Martinek 1 1 Elisabethinen University Teaching Hospital of the Universities Innsbruck, Vienna and Graz; Linz, Austria, Linz, Austria

40

7-6 Abstract 18-35 PROGNOSTIC VALUE OF ENDOCARDIAL MAPPING RESULTS IN PEDIATRIC PA-TIENTS WITH IDIOPATHIC VENTRICULAR ARRHYTHMIAS Sergey Termosesov 1, Igor Khamnagadaev 1, Maria Shkolnikova 1, Ilya Ilich 1, Yanina Volkova 1, Rustem Garipov 1 1 Research and Clinical Institute for Pediatrics at the Pirogov Russian National Research Medical University, Moscow, Russia

MONDAY APRIL 20, 2015 10:30 AM - 12:00 PM ROOM PASCAL Abstract Oral Session 8

Clinical and genetic aspects of ARVD/C Chairpersons: Hugh Calkins (Baltimore, USA), Richard Hauer (Utrecht, NL) 8-1 Abstract 07-12 CLINICAL CHARACTERISTICS AND OUTCOME OF PEDIATRIC-ONSET AR-RHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY Anneline S. te Riele 1, Cynthia A. James 1, Abhishek C. Sawant 1, Brittney Murray 1, Crystal Tichnell 1, Ryan Tedford 1, Jane Crosson 1, Daniel P. Judge 1, Hugh Calkins 1, Harikrishna Tandri 1 1 Johns Hopkins University School of Medicine, Baltimore, United States 8-2 Abstract 07-19 SARCOMERIC MUTATIONS ARE ASSOCIATED WITH ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY (ARVD/C) Dennis Dooijes, University Medical Center Utrecht, Utrecht, The Netherlands; Judith A Groeneweg, University Medical Center Utrecht and Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands; Brittney Murray, Johns Hopkins University School of Medicine, Baltimore, Maryland; Daniel P Judge, Johns Hopkins University School of Medicine, Baltimore; Crystal Tichnell, Johns Hopkins University School of Medicine, Baltimore, Maryland; Jan DH Jongbloed, University Medical Center Groningen, Groningen, The Netherlands; J Peter van Tintelen, University Medical Center Groningen, Groningen, The Netherlands; Hugh Calkins, Johns Hopkins University School of Medicine, Baltimore, Maryland; Richard N Hauer, University Medical Center Utrecht and Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands; Cynthia A James, Johns Hopkins University School of Medicine, Baltimore, Maryland;

8-3 Abstract 07-18 PREGNANCY IN ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY IS ASSOCIATED WITH A LARGELY UNEVENTFUL COURSE DELIVERY Anke R. Hodes 1, Crystal Tichnell 2, Anneline S.J.M. te Riele 3, Brittney Murray 2, Judith A. Groeneweg 4, Abhishek C. Sawant 2, Stuart D. Russell 2, Maarten P. van den Berg 1, Arthur A. Wilde 5, Harikrishna Tandri 2, Daniel P. Judge 2, Richard N.W. Hauer 4, Hugh Calkins 2, J. Peter van Tintelen 5, Cynthia A. James 2 1 University Medical Center Groningen, Groningen, Netherlands, 2 Johns Hopkins University, Baltimore, United States, 3 University Medical Center Utrecht, Utrecht, Netherlands, 4 Interuniversity Cardiology Institute of the Netherlands, Utrecht, Netherlands, 5 Academic Medical Center, Amsterdam, Netherlands

41

8-4 Abstract 07-15 ARRHYTHMOGENIC RIGHT VENTRICLAR DYSPLASIA DURING PREGNANCY: RETROSPECTIVE STUDY OF 21 PATIENTS Emilie Varlet 1, Jacky Nizard 2, Guillaume Duthoit 2, Veronique Fressart 2, Nicolas Badenco 2, Xavier Waintraub 2, Caroline Himbert 2, Carole Maupain 2, Thomas Chastre 2, Françoise Hidden-Lucet 2, Estelle Gandjbakhch 2 1 Hopital Bichat, Paris, France, 2 Hopital La Pitie Salpetriere, Paris, France

8-5 Abstract 07-14 PREDICTIVE VALUE OF LOCAL PROLONGED ELECTRO-MECHANICAL INTERVAL IN THE CONCEALED STAGE OF ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY Thomas P Mast 1, Arco J Teske 1, Anneline S Te Riele 1, Judith A Groeneweg 1, Jeroen F Heijden van der 1, Birgitta K Velthuis 1, Peter Loh 1, Pieter A Doevendans 1, Dennis Dooijes 1, Jaques M Bakker de 2, Richard N Hauer 3, Maarten J Cramer 1 1 UMC Utrecht, Utrecht, Netherlands, 2 AMC Amsterdam, Amsterdam, Netherlands, 3 ICIN - Netherlands Heart Institute, Utrecht, Netherlands

8-6 Abstract 03-12 A NEW RYANODINE RECEPTOR MUTATION ILLUSTRATES THE NEED FOR FAMILY-CENTERED CARE AND GENETIC TESTING IN PATIENTS WITH FAMILIAL ARRHYTHMOGENIC DISORDERS Cordula M Wolf 1, Isabel Deisenhofer 1, Michaela Horndasch 1, Heide Seidel 1, Peter Ewert 1, Gabriele Hessling 1 1 German Heart Centre Munich / Technical University Munich, Munich, Germany

MONDAY APRIL 20, 2015 08:30 AM - 10:30 AM ROOM GAUGUIN Chaired Poster session C Part 2 Posters exposed from 8:30 AM - 12:00 PM Presenters and chairpersons present from 10:30 AM - 12:00 PM

Chairpersons: David Cannom (Los Angeles, USA), Jacques Clementy (Bordeaux, FR)

15-16 Abstract 19-17 SUDDEN CARDIAC DEATH IN YOUNG WOMEN IN DENMARK Bo Gregers Winkel 1, Bjarke Risgaard 1, Reza Jabbari 1, Thomas Hadberg Lynge 1, Charlotte Glinge 1, Henning Bundgaard 1, Stig Haunsø 1, Jacob Tfelt-Hansen 1 1 Rigshospitalet, department of Cardiology, Copenhagen, Denmark

15-17 Abstract 19-21 SUDDEN CARDIAC DEATH PROTOCOL ANALYSIS OF POSTMORTEM AUTOPSIES Sergey Mikhaylichenko 1, Vladimir Gorbunov 2, Egor Bogatikov 2, Maxim Mikhaylichenko 2 1 Bakoulev Center for Cardiovascular Surgery, Moscow, Russia, 2 Chita State Medical Academy, Chita, Russia

15-18 Abstract 31-15 CLINICAL CHARACTERISTICS AND EVOLUTION OF PATIENTS WITH AN IMPLANTABLE CARDIOVERTER DEFIBRILLATOR THAT HAVE BEEN TRANSPLANTED. Francisco Méndez Z 1, Enrique Rodriguez 1, Concepción Alonso 1, José Guerra 1, Eulalia

42

Roig 1, Sonia Mirabet 1, Marcos Rodríguez G 1, Xavier Viñolas P 1 1 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

15-19 Abstract 25-10 IS IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR REPLACEMENT NECESSARY IN THE PRIMARY PREVENTION PATIENT WHOSE LEFT VENTRICULAR EJECTION FRACTION HAS NORMALIZED? JoEllyn Abraham 1, Deepa McGriff 1, Charles O'Hare 1, Raed Abdelhadi 1, Jay Sengupta 1, Robert Hauser 1 1 Minneapolis Heart Institute, Abbott Northwestern Hospital, part of Allina Health, Minneapolis, United States,

15-20 Abstract 25-11 IMPLANTED CARDIOVERTER DEFIBRILLATOR SHOCK RISK AND MORTALITY IN WOMEN WITH ADRIAMYCIN-INDUCED CARDIOMYOPATHY Marc Lahiri 1, Arfaat Khan 1, Gurjit Singh 1, Claudio Schuger 1 1 Henry Ford Hospital, Detroit, MI, United States

15-21 Abstract 19-10 INAPPROPRIATE SUBCUTANEOUS IMPLANTABLE CARDIOVERTER DEFIBRILLATOR SHOCKS DUE TO T-WAVE OVERSENSING CAN BE PREVENTED. Kirsten M. Kooiman 1, Reinoud E. Knops 1, Louise R. Olde Nordkamp 1, Arthur A. Wilde 1, Joris R. de Groot 1 1 Academic Medical Centre , Amsterdam , Netherlands

15-22 Abstract 19-18 SUB-MAMMARY ICD IMPLANTATION: LEAD CHARACTERISTICS, LONGEVITY, AND COMPLICATIONS. A RETROSPECTIVE REVIEW. Nicole E Worden 1, Lee Joseph 1, Chad C Ward 1, Samih L Khauli 1, Brodie R Marthalar 1, Musab N Alqasrawi 1, Michael C Giudici 1 1 University of Iowa Hospitals and Clinics, Iowa City, United States

15-23 Abstract 19-20 INFLUENCE OF TELEMONITORING SYSTEMS ON QUALITY OF LIFE AND DEVICE-ACCEPTANCE IN PATIENTS WITH IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS – 12 MONTHS FU DATA Johannes Siebermair 1, Eimo Martens 1, Florian Leppert 2, Stefanie Fichtner 1, Stefan Sattler 1, Heidi Estner 1, Regina Freeden 3, Alexander Balke 3, Josef Lauter 3, Wolfgang Greiner 2, Reza Wakili 1, Stefan Kääb 1 1 Medizinische Klinik und Poliklinik I, LMU Klinikum der Universität München, München, Germany, 2 Fakultät für Gesundheitswissenschaften, Universität Bielefeld, Bielefeld, Germany, 3 Medtronic, Meerbusch, Meerbusch, Germany

15-24 Abstract 19-22 REDUCTION OF INAPPROPRIATE THERAPIES : REMOTE MONITORING FOLLOW-UP OF 387 CRT-D Peggy Jacon 1, Alix Martin 1, Natacha Pellet 1, Hager Rekik 1, Jean Jacques Ndjessan 1, Pascal Defaye 1 1 CHU Grenoble, Grenoble, France

15-25 Abstract 19-23 DEFIBRILLATION THRESHOLD TESTING – IS IT STILL NECESSARY FOR ANY PATIENT SUBGROUP? A LARGE REAL LIFE ANALYSIS Eimo Martens 1, Johannes Siebermair 1, Regina Freeden 2, Carsten Koenig 2, Stefan Veith 1, Moritz Sinner 1, Stefan Kääb 1

43

1 Klinikum der Universität Muenchen, Muenchen, Germany, 2 Medtronic GmbH, Meerbusch, Germany

15-26 Abstract 19-28 PROJECTED NUMBERS OF REPLACEMENTS REQUIRED DURING NATURAL LIFESPAN OF CRTD/ICD RECIPIENTS Ernest Lau 1, Eric Hammill 2, Nicholas Wold 2 1 Royal Victoria Hospital, Belfast, United Kingdom, 2 Boston Scientific Corp, St Paul, United States

15-27 Abstract 19-29 IMPLANTABLE CARDIAC DEFIBRILLATOR AMONG ADULTS WITH TRANSPOSITION OF THE GREAT ARTERIES AND ATRIAL SWITCH OPERATION Abdeslam Bouzeman 1, Eloi Marijon 1, Maxime De Guillebon 2, Magalie Ladouceur 1, Guillaume Duthoit 3, Raphael Martins 4, Pierre Bordachar 2, David Celermajer 5, Jean-Benoit Thambo 2, Laurence Iserin 1, Nicolas Combes 6 1 European Georges Pompidou Hospital, Cardiology Department, Paris, France Paris Cardiovascular Research Center, Paris, France, Paris, France, 2 CHU Haut Leveque, Cardiology Department, Bordeaux, France, Bordeaux, France, 3 CHU La Pitie Salpetriere Hospital, Cardiology Department, Paris, France, Paris, France, 4 CHU Pontchaillou, Cardiology Department, Rennes, France, Rennes, France, 5 Sydney Medical School, Sydney, Australia, 6 Clinique Pasteur, Toulouse, France

15-28 Abstract 19-11 AZYGOS VEIN COIL: AN ATRACTIVE ALTERNATIVE Andrew Behunin 1, Michael Giudici 1, Prashant Bhave 1, Alexander Mazur 1, Dwayne Campbell 1 1 University of Iowa Hospitals and Clinics, Iowa City, United States

15-29 Abstract 19-13 REDUCTION OF INAPPROPRIATE SHOCK THERAPY IN S-ICD PATIENTS THROUGH INTRAOPERATIVE SELECTION OF IMPLANTATION SITE ACCORDING TO NEUROANATOMICAL CRITERIA OF SENSORY NERVE SUPPLY IN ADJACENT THORACIC MUSCLE Ulrich Backenkoehler 1 1 Praxis für Kardiologie, Hamburg, Germany

15-30 Abstract 19-15 IMPLANTABLE CARDIOVERTER DEFIBRILLATOR IN PRIMARY PREVENTION FOR CHRONIC HEART FAILURE: INCIDENCE AND PREDICTORS OF APPROPRIATE THERAPY. Arsène Monnier 1, François Lesaffre 1, Jean Pierre Chabert 1, Pierre Nazeyrollas 1, Damien Metz 1 1 Service de Cardiologie CHU de Reims, Reims, France

Luncheon Panels

12:15 PM-1:45 PM Room Dufy

Luncheon Panel 2 Supported by Bayer Healthcare

44

MONDAY APRIL 20, 2015 2:00 PM - 3:30 PM ROOM COROT Session AB-04

Current issues in atrial fibrillation

Chairpersons: Antonio Raviele (Venice, IT), Leonardo Calo (Rome, IT) 1. Patients Selection: Do we already need updated guidelines?

Riccardo Cappato (Milan, IT) 2. Periprocedural Anticoagulation for AF ablation with warfarin and NOACs:

beyond clinical stroke prevention Etienne Aliot (Nancy, FR)

3. Energy Sources and tools: To whom, when and why?

New generation cryothermia balloon Ellen Hoffmann (Munich, DE)

4. Laser balloon ablation

Thomas Deneke (Bad Neustadt, DE) 5. Lesion visualization and future directions

Matthew Wright (London, GB)

MONDAY APRIL 20, 2015 2:00 PM - 3:30 PM ROOM DIDEROT Session HD-06

Biomarker-based therapeutic decision making in atrial fibrillation

Chairpersons: Stefan Kääb (Munich, DE), Nicholas Peters (London, GB) 1. Biosignals- AF complexity guiding treatment strategies?

Ulrich Schotten (Maastricht, NL) 2. Biomarkers for the patient at risk for AF

Moritz Sinner(Munich, DE) 3. Genetics of AF – Ready for clinical decision making?

Stefan Kääb (Munich, DE) 4. MicroRNAs- Potential biomarkers for AF and AF therapy?

Reza Wakili (Munich, DE)

MONDAY APRIL 20, 2015 2:00 PM - 3:30 PM ROOM DESCARTES Session HD-07

45

HRS-ECAS SPECIAL SESSION ECAS-HRS Joint Special Session (organized by Richard Hauer)

Arrhythmogenic Cardiomyopathy II Risk Stratification and Therapy Chairpersons: Corrina Brunckhorst (Zurich, CH), Richard Hauer (Utrecht, NL)

1. Electrophysiologic substrate and risk Stratification Alessandro Zorzi (Padova, IT)

2. Long-term Follow-up of ICD Therapy in ARVD/C Hugh Calkins (Baltimore, USA) 3. Towards Elimination of the Electrophysiologic Substrate

Francis Marchlinski (Philadelphia, USA) 4. Towards New Drug Therapy

Jeffrey Saffitz (Boston, USA)

MONDAY APRIL 20, 2015 2:00 PM - 3:30 PM ROOM PASCAL Session SP-15

Approaches in VT Ablation Chairpersons: Francis Marchlinski (Philadelphia, USA), Walid Saliba (Cleveland, USA)

1. Mechanisms of VT in structural heart disease Michiel Janse (Amsterdam, NL) 2. Ischemic cardiomyopathy: The homogenization approach

Andrea Natale (Austin, USA) 3. VT ablation in non- ischemic cardiomyopathy

Jasbir Sra (Milwaukee, USA) 4. The impact of pre and post VT ablation inducibility on long term success, re-

hospitalization and mortality. Gerhard Hindricks (Leipzig, DE)

MONDAY APRIL 20, 2015 2:00 PM - 5:00 PM ROOM GAUGUIN Chaired Poster Session D part 1 Posters exposed from 2:00 PM - 5:00 PM Presenters and chairpersons present from 2:00 PM - 3:30 PM

Pacing and related complications

46

Chairpersons: Massimo Santini (Rome, IT), Mark Estes III (Boston, USA)

16-1 Abstract 22-10 LIMITED VASCULAR ACCESS AND CARDIAC PACEMAKER IMPLANTATION – A NEW APPROACH Niall Campbell 1, Ross Hunter 1, Richard Schilling 1 1 Queen Mary, University of London, London, United Kingdom 16-2 Abstract 23-12 THE PROBABILITY OF FORMATION OF VEGETATIONS IN PATIENTS WITH LEAD DEPENDENT INFECTIVE ENDOCARDITIS Anna Polewczyk 1, Wojciech Jacheć 2, Andrzej Tomaszewski 3, Wojciech Brzozowski 3, Maranna Janion 1, Andrzej Kutarski 3 1 Swietokrzyskie Cardiology Center, II Department of Cardiology,The Jan Kochanowski University, Department of Health Sciences , Kielce, Poland, 2 Silesian Medical University, II Cardiology Department, Zabrze, Poland, 3 Medical University, Department of Cardiology , Lublin, Poland

16-3 Abstract 23-17 IS TRANSVENOUS LEADS EXTRACTION MORE RISKY IN PATIENTS WITH VEGETATIONS? Anna Polewczyk 1, Andrzej Tomaszewski 2, Wojciech Brzozowski 2, Marianna Janion 1, Andrzej Kutarski 2 1 Swietokrzyskie Cardiology Center, II Department of Cardiology;The Jan Kochanowski University, Department of Health Sciences , Kielce, Poland, 2 Medical University, Department of Cardiology , Lublin, Poland

16-4 Abstract 23-20 DRY PERFORATION - FREQUENT MECHANISM OF ICD LEAD DYSFUNCTION Andrzej Kutarski 1, Andrzej Tomaszewski 1, Wojciech Brzozowski 1, Krzysztof Oleszczak 1 1 Dept. of Cardiology, Medical University , Lublin, Poland

16-5 Abstract 23-13 LONG-TERM FOLLOW RELIABILITY OF SWEET-TIP TYPE SCREW-IN LEADS IN A SINGLE JAPANESE HEART CENTER Hidemori Hayashi 1, Richard Schlling 1, Asuka Takano 2, Gaku Sekita 2, Hiroyuki Daida 2, Yuji Nakazato 3 1 St Bartholomew's Hospital, London, United Kingdom, 2 Juntendo University Hospital, Tokyo, Japan, 3 Juntendo Urayasu Hospital, Chiba, Japan

16-6 Abstract 23-11 THE INFLUENCE OF VEGETATIONS ON CLINICAL PRESENTATION OF LEAD DEPENDENT INFECTIVE ENDOCARDITIS Anna Polewczyk 1, Andrzej Tomaszewski 2, Wojxiech Brzozowski 2, Marianna Janion 1, Andrzej Kutarski 2 1 Swietokrzyskie Cardiology Center II Department of Cardiology The Jan Kochanowski University, Department of Health Sciences , Kielce, Poland, 2 Medical University, Department of Cardiology , Lublin, Poland

16-7 Abstract 23-10 UNDECIDED ABOUT GETTING A PACEMAKER? TAKE ONE FOR A TEST-DRIVE Michael Giudici 1 1 University of Iowa Hospitals, Iowa City, United States

47

16-8 Abstract 23-24 POLYPROPYLENE BYRD DILATOR SHEATH FRACTURE - MAY LEAD TO SERIOUS PROBLEMS IF NOT IDENTIFIED ON TIME. Andrzej Kutarski 1, Maciej Polewczyk 2, Aneta Polewczyk 2, Anna Polewczyk 3 1 Dept of Cardiology Medical University , Lublin, Poland, 2 District Hospital, Kielce, Poland, 3 II Dept. of Cardiology Swiektokrzyskie Cardiology Center; Dept. of Health Scientes The Jan Kochanowski University, Kielce, Poland

16-9 Abstract 31-13 TIME COURSE AND CHARACTERISTICS OF TACHYARRHYTHMIAS AFTER IMPLANTATION OF THE HEARTMATE II Ameeta Yaksh 1, Charles Kik 1, Paul Knops 1, Korinne Zwiers 1, Maarten J.B. Van Ettinger 1, Marcel C.J. De Wijs 1, Peter Van de Kemp 2, Olivier C. Manintveld 1, Alina A. Constantinescu 1, Ad J.J.C. Bogers 1, Natasja N.M. De Groot 1 1 Erasmus MC, Rotterdam, Netherlands, 2 Sorin, Rotterdam, Netherlands

16-10 Abstract 23-16 TRANSVENOUS LEADS EXTRACTION IN DIABETIC PATIENTS- SAFETY AND EFFECTIVENESSESS, SINGLE CENTER ANALYSIS AMONG 1715 PROCEDURES Anna Polewczyk 1, Andrzej Tomaszewski 2, Wojciech Brzozowski 2, Marianna Janion 1, Andrzej Kutarski 2 1 Swietokrzyskie Cardiology Center, II Department of Cardiology; The Jan Kochanowski University, Department of Health Sciences , Kielce, Poland, 2 Medical University, Department of Cardiology , Lublin, Poland

Atrial fibrillation and anticoagulant therapy

16-11 Abstract 15-18 A CROSS-SECTIONAL SURVEY ON THE PERCEPTION OF THE ANTICOAGULANT TREATMENT IN ATRIAL FIBRILLATION IN PHYSICIANS FROM COUNTY HOSPITALS Yihong Sun 1, Changying Wang 2, Yitong Wang 1, Dayi Hu 3, Lina Wang 3 1 Heart Center, Peking University People’s Hosiptal, Beijing, China, 2 Department of Cardiology,The First Affiliated Hosiptal of Chongqing Medical University, Chongqing, China, 3 Peking University People's University, Beijing, China

16-12 Abstract 15-17 APIXABAN 2.5 MG BID CAN REVERSE LEFT ATRIAL APPENDAGE CLOT. Magdi Sami 1, Beatriz Vaquerizo 1 1 McGill University, Montreal, Canada

16-13 Abstract 14-14 A CROSS-SECTIONAL SURVEY ON THE PERCEPTION OF THE ANTICOAGULANT TREATMENT IN ATRIAL FIBRILLATION IN PHYSICIANS FROM COUNTY HOSPITALS Yihong Sun 1, Changying Wang 2, Yitong Wang 1, Dayi Hu 1, Lina Wang 1 1 Heart Center, Peking University People’s Hosiptal, Beijing, China, 2 Department of Cardiology,The First Affiliated Hosiptal of Chongqing Medical University,, Chongqing, China

16-14 Abstract 15-50 DIFFERENT ORAL ANTICOAGULANTS IN REAL – LIFE PATIENTS WITH ATRIAL FIBRILLATION : CLINICAL ASPECTS AND PROBLEMS Olga Litunenko 1, Baiba Lurina 1, Marina Kovalova 2, Gita Rancane 3, Iveta Sime 4, Valters Stirna 4, Galina Dormidontova 5, Janis Guslens 6, Biruta Tilgale 7, Davis Polins 1, Janis Raibarts 1, Janis Pudulis 7, Evija Miglane 8, Aivars Lejnieks 7, Oskars Kalejs 8 1 Riga Stradins University, Riga, Latvia, 2 Jelgava Regional Hospital, Jelgava, Latvia, 3

48

Ventspils Regional Hospital, Ventspils, Latvia, 4 Liepaja Regional Hospital, Liepaja, Latvia, 5 Daugavpils Regional Hospital, Daugavpils, Latvia, 6 Riga Technical University, Riga, Latvia, 7 Riga East University Hospital, Riga, Latvia, 8 P.Stradins Clinical University Hospital, Riga, Latvia

16-15 Abstract 01-18 ASSESSMENT OF THE SPATIO-TEMPORAL STABILITY OF VOLTAGE DURING ATRIAL FIBRILLATION: QUANTIFYING THE TIME COUSE OF MEAN PEAK-TO-PEAK AF VOLTAGE ALLOWS FOR MEANINGFUL SPATIAL DIFFERENTIATION FOR THE PERSISTENT AF SUBSTRATE Norman Qureshi 1, Matt Shun-Shin 1, Steve Kim 2, Chris Cantwell 1, Rheeda Ali 1, Caroline Roney 1, Fu Siong Ng 1, Arunashis Sau 1, Sajad Hayat 1, Michael Kao-Wing 1, Elaine Lim 1, Ian Wright 1, Nick Linton 1, David Lefroy 1, Zachary Whinnett 1, D Wyn Davies 1, Prapa Kanagaratnam 1, Nicholas Peters 1, Phang Boon Lim 1 1 Imperial College, London, United Kingdom, 2 St Jude Medical, St Paul, MN, United States

3:30 PM - 4:00 PM Coffee break and Posters

MONDAY APRIL 20, 2015 4:00 PM - 5:30 PM ROOM COROT Session AB-05

AF ablation techniques not targeting the pulmonary veins

Chairpersons: Riccardo Cappato (Milan, IT), David Wilber (Maywood, USA)

1. Detection and role of non-pulmonary vein AF triggers Richard Schilling (London, GB)

2. Targeting complex fractionated atrial electrograms Julien Seitz (Marseille, FR) 3. Mapping techniques for detecting rotors

Omer Berenfeld (Ann Arbor, USA) 4. Rotors-based AF ablation strategies

Paul Wang (Stanford, USA)

MONDAY APRIL 20, 2015 4:00 PM - 5:30 PM ROOM DIDEROT Session SP-14

8th Japanese HRS/ ECAS SYMPOSIUM

New Insights in CRT therapy Chairpersons: Yuji Nakazato (Chiba, JP), Gilles Lascault (Paris, FR) 1. Impact of multisite LV pacing in heart failure patients

Werner Jung (Villingen, DE)

49

2. Trans-septal endocardial LV pacing Hidemori Hayashi, (London, GB) 3. Role of surgical approach: An update Katsuhiko Imai (Hiroshima, JP) 4. Clinical efficacy of optimization algorithm Toshiiyuki Ishikawa (Yokohama, JP)

MONDAY APRIL 20, 2015 4:00 PM - 5:30 PM ROOM DESCARTES Session SP-13

Sudden cardiac death on a population level – Stratification methods for the patient with ejection fraction > 35 % Chairpersons: Stefan Kääb (Munich, DE), Brian Olshansky (Iowa City, USA) 1. Epidemiology of SCD Xavier Jouven (Paris, FR) 2. ECG – Risk stratification for SCD Pieter Postema (Amsterdam, NL) 3. Holter-ECG: Potential parameters for risk stratification Marek Malik (London, GB) TBC 4. Genetics of SCD- What have we learned? Vincent Probst (Nantes, FR)

MONDAY APRIL 20, 2015 4:00 PM - 5:30 PM ROOM PASCAL Session HD-04

Role of the autonomic nervous system in cardiac arrhythmias Chairpersons: Gunter Breithardt (Muenster, DE), Shlomo Ben Haim (London-GB) 1. Role of multimodal imaging in arrhythmia patients

Reza Wakili (Munich, DE) 2. Risk stratification by autonomic biosignaling

Axel Bauer (Munich DE) 3. Role of sympathetic innervation in ARVD patients

Matthias Paul (Munich, DE) 4. Autonomic testing for risk stratification in Long-QT patients

Peter Schwartz (Milan, IT)

50

5. Renal Denervation – A treatment option for ventricular storm tachycardias

Noel Boyle (Los Angeles, USA)

MONDAY APRIL 20, 2015 4:00 PM - 5:30 PM ROOM GAUGUIN Chaired Poster session D part 2 Posters exposed from 2:00 PM - 5:00 PM Presenters and chairpersons present from 3:30 PM - 5:00 PM

Syncope Chairpersons: Andrzej Kutarski (Lublin, PL), Ernst Vester (Dusseldorf, DE)

16-17 Abstract 10-15 CARDIONEUROBLATION IN THE RIGHT ATRIUM AS THERAPY FOR CARDIOINHIBITORY NEUROCARDIOGENIC SYNCOPE Marco Rebecchi 1, Luigi Sciarra 1, Ermenegildo De Ruvo 1, Alessio Borrelli 1, Antonella Sette 1, Antonio Scarà 1, Domenico Grieco 1, Marianna Sgueglia 1, Alessandro Politano 1, Annamaria Martino 1, Giacomo Strano 2, Stefano Strano 2, Leonardo Calò 1 1 Policlinico Casilino, ASL RMB, Rome, Italy, 2 Università of Rome " La Sapienza", Rome, Italy

16-18 Abstract 10-10 THE IMPACT OF GENDER ON THE FREQUENCY OF SYNCOPE PROVOKING FACTORS AND PRODROMAL SIGNS IN PATIENTS WITH VASOVAGAL SYNCOPE Piotr J. Stryjewski1,Agnieszka Kuczaj2, Jadwiga Nessler3, Bohdan Nessler3, Ryszard Braczkowski4, Donat Domaradzki5, Ewa Nowalany-Kozielska2, 1Cardiology Department, Chrzanow City Hospital, Poland 22nd Department of Cardiology, Zabrze, Medical University of Silesia, Katowice, Poland 3Coronary Disease Department, Institute of Cardiology, Medical School of Jagiellonian University, John Paul II Hospital, Cracow, Poland 4Department of Public Health, Medical University of Silesia, Katowice, Poland 5Department of Diagnosis, John Paul II Hospital, Cracow, Poland

16-19 Abstract 10-16 COMPARISON OF SYNCOPE PRODROMAL SIGNS REPORTED DURING HEAD-UP TILT TEST WITH OCCURRING BEFORE SPONTANEOUS SYNCOPAL EPISODES IN PATIENTS WITH VASOVAGAL SYNCOPE Piotr Stryjewski 1, Agnieszka Kuczaj 2, Ryszard Braczkowski 3, Jadwiga Nessler 4, Bohdan Nessler 4, Ewa Nowalany-Kozielska 2 1 Cardiology Department, Chrzanow City Hospital, Poland, Chrzanow, Poland, 2 2nd Department of Cardiology, Zabrze, Medical University of Silesia, Katowice, Poland, Zabrze, Poland, 3 Silesian Medical University, School of Public Health, Department of Public Health Bytom, Poland, Bytom, Poland, 4 Coronary Disease Department, Institute of Cardiology, Medical School of Jagiellonian University, John Paul II Hospital, Cracow, Poland, Krakow, Poland

Ablation of ventricular arrhythmias

51

16-20 Abstract 28-17 ROLE OF NEGATIVE CONCORDANCE OF UNIPOLAR AND BIPOLAR ELECTROGRAMS IN THE SINGLE CATHETER DETERMINATION OF SITE OF ORIGIN OF FOCAL ARRHYTHMIAS Gianluca Epicoco 1, Antonio Sorgente 1, Hussam Ali 1, Gianluca Bonitta 1, Sara Foresti 1, Guido De Ambroggi 1, Cristina Balla 1, Marco Matteo Ciccone1

, Pierpaolo Lupo 1, Riccardo Cappato 1 1 IRCCS Policlinico San Donato, San Donato Milanese, Italy

16-22 Abstract 28-21 PROCEDURAL BENEFIT OF SUBSTRATE BASE ABLATION VERSUS CONVENTIONAL MAPPING AND ABLATION OF CLINICAL STABLE VENTRICULAR TACHYCARDIA: RESULTS FROM THE VISTA RANDOMIZED TRIAL Luigi Di Biase1; J. David Burkhardt2, Dhanujaya R. Lakkireddy3, Corrado Carbucicchio4, Sanghamitra Mohant2 Chintan Trivedi2, Prasant Mohanty2 , Pasquale Santangeli2, Rong Bai2, Giovanni Forleo5, Rodney Horton2 Shane Bailey2, Javier Sanchez2, Amin Al-Ahmad2 Patrick Hranitzky2, Gemma Pelargonio6, Richard Hongo, Salwa Beheiry7, Steven Hao7; Madhu Reddy3; Antonio Rossillo8, Sakis Themistoclakis8; Antonio Dello Russo4, Claudio Tondo4, Andrea Natale2 1. Albert Einstein Coll of Med at Montefiore Hosp And Texas Cardiac Arrhythmia Inst at St David's Medical Ctr, New York and Austin, TX. 2. Texas Cardiac Arrhythmia Inst at St. David's Medical Ctr, Austin, TX;3. Univ of Kansas Medical Ctr, Kansas City, KS;4 Cardiac Arrhythmia Res Ctr, Ctr Cardiologico Monzino, IRCCS, Milan, Italy;5. Univ of Tor Vergata, Rome, Italy;6. Catholic Univ of the Sacred Heart - Insitute of Cardiology, Rome, Italy; 7. California Pacific Medical Ctr, San Francisco, CA;8. Ospedale Dell'Angelo - Mestre, Mestre-Venice, Italy

16-23 Abstract 18-29 CATHETER-INDUCED MECHANICAL TRAUMA DURING ABLATION OF OUTFLOW TRACT VENTRICULAR ARRHYTHMIAS: INCIDENCE AND CLINICAL IMPLICATIONS. Jeremy Ben-Shoshan 1, Yoav Michowitz 1, Aharon Glick 1, Bernard Belhassen 1 1 Tel-Aviv Medical Center, Tel-Aviv, Israel 16-24 Abstract 18-27 REMOTE MAGNETIC NAVIGATION VERSUS MANUALLY CONTROLLED CATHETER ABLATION OF RIGHT VENTRICULAR OUTFLOW TRACT VENTRICULAR ARRHYTH-MIAS: A RETROSPECTIVE SINGLE CENTER EXPERIENCE Ayelet Shauer 1, Jorge Palazzolo 1, Mohammed Shurrab 1, Sheldon Singh 1, Ilan Lashevsky 1, Irvin Tiong 1, David Newman 1, Eugene Crystal 1 1 Sunnybrook Health Sciences Centre, Toronto, Canada 16-25 Abstract 18-23 SIMULTANEOUS UNIPOLAR RADIOFREQUENCY ABLATION OF VENTRICULAR TACHYCARDIA USING TWO ABLATION CATHETERS Vivek Iyer 1, Alok Gambhir 1, Shalin P. Desai 1, Hasan Garan 1, William Whang 1 1 Columbia University Medical Center, New York, United States 16-26 Abstract 14-13 EFFICACY AND SAFETY OUTCOMES OF VARIOUS RATE CONTROL STRATEGIES FOR PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE WITH REDUCED EJECTION FRACTION AND ATRIAL FIBRILLATION OR FLUTTER WITH RAPID VENTRICULAR RESPONSE Lee Joseph 1, Siva Krothapalli 1, Omer Iqbal 1, Olurotimi Mesubi 1, Hardik Doshi 1, Nicole

52

Worden 1, Jayasheel Eshcol 1, Musab Alqasrawi 1, Prashant Bhave 1, Michael Giudici 1 1 University of Iowa, Iowa City, United States

16-27 Abstract 31-12 RHYTHM VERSUS RATE CONTROL FOR PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE WITH REDUCED EJECTION FRACTION AND ATRIAL FIBRILLATION OR FLUTTER WITH RAPID VENTRICULAR RESPONSE Lee Joseph 1, Nicole Worden 1, Jayasheel Eshcol 1, Hardik Doshi 1, Siva Krothapalli 1, Omer Iqbal 1, Olurotimi Mesubi 1, Musab Alqasrawi 1, Prashant Bhave 1, Michael Giudici 1 1 University of Iowa, Iowa City, United States

16-28 Abstract 06-10 THE LUNG IMPEDANCE MONITORING IN TREATMENT OF CHRONIC HEART FAILURE: PRELIMINARY RESULTS FROM THE LIMIT-CHF STUDY Giulia Domenichini 1, Cveta Rahneva 1, Ihab Diab 1, Onkar Dhillon 1, Victoria Baker 1, Ross Hunter 1, Mark Earley 1, Richard Schilling 1 1 Department of Cardiology, St Bartholomew’s Hospital, London, United Kingdom

16-29 Abstract 15-23 OUTCOMES OF RHYTHM CONTROL FOR ATRIAL FIBRILLATION/FLUTTER IN ACUTE DECOMPENSATED HEART FAILURE Jayasheel Eshcol 1, Michael Giudici 1, Lee Joseph 1, Nicole Worden 1, Musab Alqasrawi 1, Hardik Doshi 1, Omer Iqbal 1 1 University of Iowa Hospitals and Clinics, Iowa City, United States

MONDAY APRIL 20, 2015 5:30 PM - 6:15 PM ROOM COROT Debate 1

Successful RF ablation alone is an acceptable treatment for monomorphic, well-tolerated VT with an ejection fraction above 30%

Chairpersons: Francis Marchlinski, (Philadelphia, USA), Gerhard Steinbeck (Munich, DE) Protagonist: Philippe Maury (Toulouse, FR) Antagonist: Brian Olshansky (Iowa City, USA)

MONDAY APRIL 20, 2015 5:30 PM - 6:15 PM ROOM DIDEROT Debate 2

Rhythm control in patients with atrial fibrillation should not be pursued vigorously in the post AFFIRM era? Chairpersons: Berndt Lüderitz (Munich, DE), Pro Obel (Johannesburg, ZA) Protagonist: A. John Camm (London, GB) Antagonist: Sanjeev Saksena (Warren, USA)

53

MONDAY APRIL 20, 2015 5:30 PM - 6:15 PM ROOM PASCAL

Debate 3 Right ventricular apical pacing should be abandoned Chairpersons: Luigi Padeletti (Florence, IT), Pascal Defaye (Grenoble, FR)

Protagonist: Werner Jung (Villingen, DE)

Antagonist: Eli Ovsyshcher (Beer Sheba, IL)

TUESDAY APRIL 21, 2015 08:30 AM - 10:00 AM ROOM DIDEROT Abstract Oral Session 9

Atrial fibrillation mechanisms I Chairpersons: Jérôme Taieb (Aix en Provence, FR), Florian Straube (Munich, DE) 9-1 Abstract 01-21 A NOVEL AUTOMATED METHOD FOR DETECTING NEAR-INSTANTANEOUS RE-INITIATION OF ATRIAL FIBRILLATION Caroline H Roney 1, Chris D Cantwell 1, Norman A Qureshi 1, Michael T Debney 1, Prapa Kanagaratnam 1, Jennifer H Siggers 1, Nicholas S Peters 1, Fu Siong Ng 1 1 Imperial College London, London, United Kingdom

9-2 Abstract 14-21 DETERMINING THE RELATIONSHIP BETWEEN RESOLUTION REQUIREMENTS AND WAVEFRONT SPATIAL WAVELENGTH FOR IDENTIFYING ROTORS, FOCI AND MULTIPLE WAVELETS Caroline H Roney 1, Chris D Cantwell 1, Rheeda L Ali 1, Norman A Qureshi 1, Eugene TY Chang 1, Phang Boon Lim 1, Spencer J Sherwin 1, Jennifer H Siggers 1, Fu Siong Ng 1, Nicholas S Peters 1 1 Imperial College London, London, United Kingdom

9-3 Abstract 14-20 EXCESSIVE ATRIAL ECTOPY AND SHORT RUNS INCREASE THE RISK OF STROKE BEYOND INCIDENT ATRIAL FIBRILLATION Bjørn Larsen 1, Preman Kumarathurai 1, Julie Falkenberg 1, Olav Wendelboe 1, Ahmad Sajadieh 1 1 Copenhagen University Hospital of Bispebjerg, København N, Denmark

9-4 Abstract 15-26 ALTERNATIVE TO CURRENT INTERVENTIONAL RATIONALES FOR PERSISTENT ATRIAL FIBRILLATION: RIGHT ATRIAL ISOLATION. Gerard Guiraudon 1, Douglas Jones 1 1 University of Western Ontarion, London-Ontario, Canada

9-5 Abstract 15-19 A CELLULAR AUTOMATON MODEL TO IDENTIFY CRITICAL SITES IN ATRIAL

54

FIBRILLATION Kishan Manani 1, Kim Christensen 1, Nicholas S Peters 1 1 Imperial College London, London, United Kingdom

9-6 Abstract 02-13 CHARACTERISATION OF BASELINE STRUCTURE OF CANINE LEFT ATRIUM DURING ACUTE INDUCED AF Christian Eichhorn 1, Rasheda A Chowdhury 1, Michael T Debney 1, Norman A Qureshi 1, Caroline H Roney 1, Nicholas S Peters 1, Fu Siong Ng 1 1 Imperial College , London, United Kingdom

TUESDAY APRIL 21, 2015 08:30 AM - 10:00 AM ROOM DESCARTES Abstract Oral Session 10

Atrial arrhythmia mechanisms II Chairpersons: Dierk Thomas (Heidelberg, DE), Luc De Roy (Brüssels, BE)

10-1 Abstract 02-10 PARTICIPATION OF MIRNAS IN ATRIAL ARRHYTHMOGENIC STRUCTURAL REMODELING IN PATIENTS WITH ATRIAL FIBRILLATION Marina Eremeeva 1, Amina Ibragimova 1, Tatiana Sukhacheva 1, Valentin Vaskovskiy 1, Amiran Revishvili 1 1 Bakoulev Center for Cardiovascular Surgery, Moscow, Russia

10-2 Abstract 01-14 DETERMINANTS OF PREFERENTIAL ROTOR LOCATIONS AND STABILITY IN ATRIAL FIBRILLATION Fu Siong Ng 1, Caroline H Roney 1, Michael T Debney 1, Christian Eichhorn 1, Arun Nachiappan 1, Norman Qureshi 1, Rasheda A Chowdhury 1, Alexander Lyon1, Nicholas S Peters 1 1 Imperial College London, London, United Kingdom

10-3 Abstract 01-11 ANTIARRHYTHMIC MECHANISMS OF SK CHANNEL INHIBITION IN THE RAT ATRIUM Lasse Skibsbye 1, Xiaodong Wang 1, Lene Axelsen 1, Morten Schak Nielsen 1, Morten Grunnet 1, Bo Bentzen 1, Thomas Jespersen 1 1 University of Copenhagen, Copenhagen, Denmark

10-4 Abstract 01-13 ELECTROGRAMS ARE MORE THAN THE SUM OF THEIR PARTS - A NEW RAT MODEL OF ATRIAL ARRHYTHMIAS REFUTES THE CRITICAL MASS HYPOTHESIS AND REVEALS NEW INSIGHTS INTO HUMAN ATRIAL FIBRILLATION Junaid Zaman 1, Pravina Patel 1, Jennifer Simonotto 1, Nicholas Peters 1 1 Imperial College London, London, United Kingdom

10-5 Abstract 01-19 THE FUNCTIONAL EXPRESSION OF ELECTROPHYSIOLOGIC PARAMETERS IN THE ORGANIZED VS. DISORGANIZED RHYTHM: A COMPARATIVE ASSESSMENT OF VOLTAGE, CONDUCTION VELOCITY, AND FRACTIONATION DURING ATRIAL FIBRILLATION AND THE PACED RHYTHM IN THE PERSISTENT AF SUBSTRATE Norman Qureshi 1, Steve Kim 2, Chris Cantwell 1, Rheeda Ali 1, Caroline Roney 1, Fu Siong

55

Ng 1, Arunashis Sau 1, Rasheda Chowdhury 1, Michael Kao-Wing 1, Sajad Hayat 1, Elaine Lim 1, Ian Wright 1, Nick Linton 1, David Lefroy 1, Zachary Whinnett 1, D Wyn Davies 1, Prapa Kanagaratnam 1, Nicholas Peters 1, Phang Boon Lim 1 1 Imperial College, London, United Kingdom, 2 St Jude Medical, St Paul, MN, United States

10-6 Abstract 02-12 VERY-LOW-DENSITY LIPOPROTEIN OF INDIVIDUALS WITH METABOLIC SYNDROME SHORTENS ATRIAL ACTION POTENTIAL DURATION BY CHANGING CALCIUM TRANSIENT Hsiang-Chun Lee 1, Wei Chi 1, Hsin-Ting Lin 1, I-Hsin Liu 1, Liang-Yin Ke 2, Chu-Huang Chen 2, Bin-Nan Wu 3, Sheng-Hsiung Sheu 1 1 Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, 2 Center of Lipid Biosciences, Kaohsiung Medical University (KMU) Hospital, KMU, Kaohsiung, Taiwan, 3 Department of Pharmacology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

TUESDAY APRIL 21, 2015 08:30 AM - 10:00 AM ROOM PASCAL Abstract Otal Session 11

Management of atrial arrhythmias

Chairpersons: Neil Sulke (Eastbourne, GB), Annibale Sandro Montenero (Rome, IT) 11-1 Abstract 15-32 NONINVASIVE ELECTROCARDIOGRAPHIC IMAGING AND CATHETER ABLATION OF PERSISTENT ATRIAL FIBRILLATION Amiran Revishvili 1, Oleg Sopov 1, Evgenii Labartkava, 1, Vitalii Kalinin 1, George Matsonashvili 1 1 1- Bakoulev Scientific Center for Cardiovascular Surgery, Moscow, Russia

11-2 Abstract 15-34 MEASUREMENT OF THE ACTIVATED CLOTTING TIME (ACT) TO CONTROL ANTICOAGULATION DURING PULMONARY VEIN ISOLATION: A COMPARISON OF METHODS Reinhard Höltgen 1, Martin Brück 2, Dirk Bandorski 3, Jessica Hirsch 4, Marcus Wieczorek 1 1 I. Medizinische Klinik - Kardiologie / Elektrophysiologie; St. Agnes-Hospital , Bocholt, Germany, 2 Medizinische Klinik I; Klinikum Wetzlar, Wetzlar, Germany, 3 Medizinische Klinik 2, Universitätsklinikum Gießen, Gießen, Germany, 4 Institut für Medizinsche Biometrie und Epidemiologie; Universität Witten/Herdecke, Witten, Germany

11-5 Abstract 15-27 IMPACT OF LEFT ATRIAL LOW VOLTAGE EXTENT ON OUTCOMES AFTER ABLATION FOR PERSISTENT ATRIAL FIBRILLATION Jeremie Sorrel 1, Amir Jadidi 1, Heiko Lehrmann 1, Thomas Arentz 1 1 Herzzentrum Bad Krozingen, Bad Krozingen, Germany

11-6 Abstract 18-30 ATRIAL TACHYCARDIAS ORIGINATING FROM THE NON CORONARY CUSPS: THE TEL-AVIV MEDICAL CENTER EXPERIENCE IN 7 PATIENTS. Yoav Michowitz 1, Raphael Rosso 1, Aharon Glick 1, Sami Viskin 1, Bernard Belhassen 1 1 Tel-Aviv Medical Center, Tel-Aviv, Israel

56

TUESDAY APRIL 21, 2015 08:30 AM - 10:00 AM ROOM TOCQUEVILLE Abstract Oral Session 12

Atrial fibrillation ablation III

Chairpersons: Sam Hanon (New-York, USA), Antony Chu (Providence, USA)

12-1 Abstract 14-16

IDIOPATHIC ATRIAL FIBRILLATION, INFLAMMATION, AND CLINICAL RESULTS

OF RADIOFREQUENCY ABLATION Roman Batalov

1, Yulia Rogovskaya

1, Viacheslav Ryabov

1, Roman Tatarskiy

1, Svetlana Sazonova

1, Mikhail Khlinin

1, Sergei Popov

1

1 RI of cardiology, Tomsk, Russia

12-2 Abstract 18-33

CHARACTERISTICS OF PATIENTS THAT FAILED CATHETER ABLATION OF ATRI-

AL FIBRILLATION, A SINGLE CENTER EXPERIENCE C Teunissen

1, J.F. vd Heijden

1, R.J. Hassink

1, W Kassenberg

1, P.A.F.M Doevendans

1, K.P. Loh

1

1 UMC Utrecht, Utrecht, Netherlands

12-3 Abstract 18-28

MECHANISMS OF ATRIAL ARRHYTHMIAS AFTER MAZE PROCEDURE AND LONG-

TERM OUTCOME AFTER CATHETER ABLATION Andrea Tordini

1, Madhan Nellaiyappan

1, Thanh Tran

1, Sanders Chae

1, Michael Fradley

1, S. Serge

Barold 1, Bengt Herweg

1

1 University of South Florida, Tampa, United States

12-4 Abstract 18-14

IMPACT OF CONTACT FORCE TECHNOLOGY ON ATRIAL FIBRILLATION

ABLATION: A META-ANALYSIS Mohammed Shurrab

1, Luigi Di Biase

2, David Briceno

2, Anna Kaoutskaia

1, David Newman

1, Ilan

Lashevsky 1, Hiroshi Nakagawa

3, Eugene Crystal

1

1 Sunnybrook Health Sciences Centre , Toronto, Canada,

2 Texas Cardiac Arrhythmia Institute ,

Austin, United States, 3 University of Oklahoma Health Sciences Center , Oklahoma City, United

States

12-5 Abstract 14-11

ANTIARRHYTHMIC THERAPY POST-ABLATION TO REDUCE ATRIAL

FIBRILLATION RECURRENCE: A META-ANALYSIS Gustavo Goldenberg

1, Daniel Burd

1, Piotr Lodzinski

2, Giussepe Stabile

3, Jacob Udell

4,

Mohammed Shurrab 1, Eugene Crystal

1

1 Sunnybrook Hospital, Toronto, Ontario, Canada,

2 Medical University of Warsaw · Department of

Cardiology, Warsaw, Poland, 3 Laboratorio di Elettrofisiologia, Casa di Cura San Michele,

Maddaloni , Italy, 4 Toronto General Hospital, Toronto, Ontario, Canada

Coffee Break

TUESDAY APRIL 21, 2015 10:30 AM - 12:00 AM ROOM DIDEROT

57

Session SP-11

Unresolved questions in the management of cardiac arrhythmias Chairpersons: Edward Rowland (London, GB), Maurice Khoury (Beirut, LB) 1. How to interpret short runs of AF on Holter monitoring?

Taya V. Glotzer (Hackensack, NJ, USA) 2. How much redo after a first AF ablation procedure? David Keane (Dublin, IE) 3. Does revascularization prevent SCD? Gerard Guiraudon (London, CA) 4. How safe are PVC's in patients without structural heart disease? Charles Jazra (Beirut, LB) 5. Ablation of PVCs: When and how?

Oussama Wazni (Cleveland, USA)

TUESDAY APRIL 21, 2015 10:30 AM - 12:00 PM ROOM DESCARTES Session SP-12

New tools and techniques for AF therapy Young German electrophysiologists – Session of the German EP Fellow program Chairpersons: Reza Wakili (Munich, DE), Roland Tilz (Hamburg, DE)

1. Potential role of multimodal mapping for a better understanding of the AF substrate

Armin Luik (Karlsruhe, DE)

2. Role of continous ECG monitoring by Implantable Loop recorders Joern Schmitt (Giessen DE)

3. The nMARQ-catheter: initial experience and results

Stephanie Fichtner (Munich DE)

4. Rotor mapping: do different tools lead to different results? Roland Tilz (Hamburg, DE)

TUESDAY APRIL 21, 2015 10:30 AM - 12:00 AM ROOM PASCAL Session WS-04

Current Issues in AF management Chairpersons: Roberto de Ponti (Varese, IT), Michiel Janse (Amsterdam, NL)

58

1. Remodelling and Antiarrhythmic Agents Dobromir Dobrev (Essen, DE)

2. Monitoring Ablation Outcomes – what really happens to AF? –

Neil Sulke (Eastbourne, GB)

3. Thoracoscopic Surgery and Hybrid Therapy Outcomes Alaadin Yilmaz (Amsterdam, NL)

4. Hot versus Cold – The latest outcomes of CRYO and RF techniques in paroxysmal and persistent AF Ross Hunter (London, GB)

TUESDAY APRIL 21, 2015 10:30 AM - 12:00 AM ROOM TOCQUEVILLE Session WS-05

Nightmares in catheter ablation: case presentations Chairpersons: Riccardo Cappato (Milan), Ali Oto (Ankara, TR) My worst case of…

1. Atrial flutter ablation Isabel Deisenhofer, (Munich, DE)

2. Atrial fibrillation ablation Nicolas Lellouche (Paris, FR)

3. Accessory pathway ablation

Peter Loh (Utrecht, NL)

4. Ventricular tachycardia ablation Bharat Kantharia (Houston, USA)

TUESDAY APRIL 21, 2015 12:00 PM – 12:30PM

ROOM DIDEROT

Results of the Best Posters Presentation Awards

59

The Organizing Committee of ECAS 2015 and the Board of ECAS wish to thank the companies which supported our Congress with an educational grant

Platinum Sponsor

Gold Sponsor

Silver Sponsor

Bronze Sponsor

Other Sponsors :

60