AMERICANAssocITION FOR THEADvANCEMENT OFSCIENCE

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23 FEBRUARY I990VOL. 247 a PAGES 893-io08

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Preliminary

PlasmidScreeningWith the

J-System

DNA Mini PrepsFast and Easy

For quick, reliable preliminaryscreening of plasmid DNA, youcan't beat the Beckman system: theJA-18.1 rotor in a J2-21 series high-speed centrifuge.

You'l appreciate the largecapacity high g-force, quiet operationand refrigerated microcentrifugecapability And Beckman service andtechnical support set the standardfor the industry

The J-System.The systematicapproach to screening plasrnids.Quickly Efficiently Only fromnBeckman. Send for a plasmid DNApreparation protocol. BeckmanInstruments, Inc., Spinco Division,1050 Page Mill Road, Palo Alto, CA94304. (800) 742-2345. Officesworldwide.

BECKIMAN

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C 1990 Beckman Instruments, Inc.

Circle No. 1 14 on Readers' Service Card

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Introducing the Brandel Superfusion 20-the first fully automated system for radioactive tagged ligand release studies.* Multi-channel design allows simultaneous perfusion of up to 20 tissue samples with up to 6 different reagents * Stimulation canbe chemical only, or chemical/electrical. Optional electrical stimulation is variable from 0-20 milliamps per channel U Featurescomputer control, manual operation, or manual interrupt with automatic resume U Microprocessor-controlled timing, flow rates, andsequence of events ensure accuracy and consistent procedure U Menu-driven software allows easy set-up, modification, verification,storage and retrieval of test parameters. Test status is displayed on-screen, including time left in current event U Reagent and reactionenvironments are water-jacketed for optional temperature control U Provision for automatic gassing of reagents U Variable pumpspeeds U Optional syringe ports permit injection of additional reagents directly into the reaction chamber U Superfusion2OA perfusesup to 20 samples for collection into standard 20 x 20 racks of 5-7ml vials U Superfusion20B perfuses up to 18 samples for collectioninto Beckman Scintillation Racks (18 x 18) of 5-7ml vials U

Orders are now being accepted, and requests for custom capabilities are being considered on an individual basis. Please contactBrandel for further information.

Harvesters O-1 Automatic Deposit and Dispensing Systems O-I Beckman CompatiblesD Superfusion2o El Supplies8561 Atlas Drive O1 Gaithersburg, MD 20877 USA O- Phone: (301) 948-6506 I Telex: 898083 L] Fax: (301) 869-5570

Orders: (1) 800-678-1558Circle No. 204 on Readers' Service Card

TrENEW STANDARJ) FORHIGH PERlFORlMANCESSTICALSOFWARE

A powerful, comprehensive, elegant, and super-fat satis-tical package for IBM (PC, AT, PS/2) and compatiblecomputers. U The C88 optmized user interface with fasthierrchicalmenus incorportes elements of artiflcial intelii-gence; even complex analy require only a few keystokes(batchpreingis also supported). 0CSS featr compre-hensive, sat of the artimplm tationsof: Basicst tiMui-way fren taes, Nonrarmeric satistiEplorry data anal with analytic grphs Muregr ionm ethods 2m riesvawyithnuwingandforasting (in full ARIMA), Geneal ANOVA/ANCOVAIMANOVA, Contrast analys Discriminant functionanalysi; Factor analysis, Principal comp nts Mui-m ional sxing, Item analysWRliabilit?g Jginranal Cluster analysis, Non-linear tiation LogWtProbit analyps Canonical analyis, Survitl and FailureThIe analysis (Ceored data), Quality Conml anaand muck me. U A s asicl procedures are integrtedwith fast data base ngement and istant, presentaonquality graphics (over 100 types); ful support for all monoand color graphs boards (incl. VGA) and over 100 plottersandprters (incl. theHPandstritsandrds). AllCS screen output isdisplayed via customized Semlheetsrm(i.e., dynamic, usercontrolled, multi-layered tableswithcellsexpandable into pop-up windows); all numbers in a ScrollsheetTm can be instantly converted into a variety ofpresentaton quallt graphs; contents of different Scroll-sheetstm can be instantly ag d, combined, compared,plotted, printed, or aved. The flexibility ofthe CSS input/output is practically unlimted: CSS offers an inteligentinterface(read/write)toallcommonfHeformats(Lotus, Sym-phony, dBI, dB f+, DIF, SYLK, . . . ) andspecialues toeasily access data from incompatible programs; graphics canbe saved in riles compatible with desktop publishing pro-grams (Aldus, Ventura). U088 data files can be as lr asyour operating stem (DOS) alows; 08/2 verson comingsoon. *08pCSion exceeds thesards of all commonprecsion benchmas. U 2 nic nte: The CSS userineface ad aU LIO wem write n in Aembler and bypasDOS; graphics and data manaement we written inAswmbler and C; the comp ion alorthms wereuwitn inAembler and optimizedFortran * $495 (plus$5 sh/h); 14-day money badk guaantee.

Circle No. 197 on Readers' Service Card

W]StatSoft 1232Sbl3ft Iret * ,674164 * (91464146ftx: (6161533.4376Ovemeas Oleer: Statof of Europe (Hamburg, FRG), ph: 040/4200347, fax: 040/4911310, SbtSoft UK (London, UK), ph: 0462/482822, fax: 0462/482855, 81ftatSftPull(Melbourne, Australia), ph: 613-497-4755, tax: 613-499-7410, Sato Caua-CCO (Ontario), ph: 416-849-0737, fax: 416-849-0918 Available From: CORPORATE SOFTWARE and otherAuthorized Representatives Woddwide: Holland: Lemax BV 02968-94210; France: Cu ptel (1) 45669700; Sweden: AkademiData 016-240035, Korea: Geul Bang (02) 272-1973

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Company, Biotechnology Systems,Lgton, DE1S9880-0016.

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This LC pump

is a dispenserand diluter,too.

It's a smartpump. Wiz® is more than anordinary peristaltic pump. Press three keysfor initial calibration when you first set itup. From then on, just key in any flow rateyou want, directly in mi/hr. The outputwill be within 1% of your selected value.

It's a dispenser, too. You can key in anyvolume-that's what you'll get every timeyou press the button.

6 And It's a diluter. Push a button to takeup any desired volume of sample: push itagain to dispense the sample followed byany volume of diluent.

Phhone toll free (800)2284250.

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Circle No. 142 on Readers' Service Card

The Foundation for Advanced Educationin the Sciences, Inc. at theNational Institutes of Health announces

MEDICAL

GENETICS: 1990Bethesda, Maryland - May 17-19, 1990The three-day course, organized by members of theNIH Interinstitute Medical Genetics Program, willinclude didactic and problem-oriented sessions.Topics include: gene structure and expression,chromosome structure, cytogenetics, reversegenetics, gene mapping, recombinant DNAtechniques in medical genetics, dysmorphology,inborn errors of metabolism, cancer genetics,endocrine genetics, neurogenetics and the geneticsof connective tissue disorders. Also included will beprenatal diagnosis, genetic counseling and newapproaches to the treatment of genetic diseases.The course is intended, in part, as a review for candi-dates for the examinations of the American Board ofMedical Genetics and will stress clinical applications,but will not ignore the excitement of current research.AMA Category I credit, 24 hours. A fee of $350 willcover tuition and syllabus ($395 after April 15).Further information is available from: Medical Genet-ics, c/o FAES, One Cloister Court, Suite 230,Bethesda, Maryland 20814-1460, (301) 496-7975.The FAES/NIH is accredited bytheAccreditation Council for Continuing MedicalEducation to sponsor continuing medical education for physicians. The FAES/NIHdesignates this continuing medical education activity for 24 credit hours inCategory 1 of the Physician's Recognition Award of the Amercan MedicalAssociation.

Women, Work, and Child Welfarein the Third World

Editors: Joanne Leslie, international nutrition con-sultant, and Michael Paolisso, anthropologistwith the Intemnational Center for Research on Women.

Enhancement of women's economic opportunitiesand raising healthy children in the Third World aretwo important development priorities dependentupon women balancing productive and reproduc-tive responsibilities. In this volume, a variety ofresearch approaches and methodologies illustratethe multifaceted nature ofwomen's work and childwelfare. The authors' carefully drawn conclusionsidentify key relationships and criteria that must beconsidered for the development of effective eco-nomic and health programs. The book is essentialreading for all researchers and policymakers con-cerned about the relationship between women'swork and child welfare in the Third World.265 pp., 1989.$28.50 ($22.80 for AAAS members who include their membershipnumber from Science).Order from: Westview Press, Dept. AAAS, 5500 Central Avenue,Boulder, CO 80301. Add $2.50 postage and handling for the first bookordered; 75c for each additional book.

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