from conception to commercialization
TRANSCRIPT
LALLEMAND HEALTH SOLUTIONS
COMPLETE SOLUTIONS. DESIGNER GUIDE.
FROM CONCEPTION TO COMMERCIALIZATION
OO O OO
ChildrenWomen
Men
Infants, toddlers
Seniors
FOR YOU TO SUCCESSFULLY REACH YOUR TARGET
Whole family
Our probiotics already enhance lives in countless ways, who’s next?We currently manufacture more than 450 unique formulas each year, marketed in more than 60 countries, covering many health segments from gastrointestinal health, immunity, women’s health and oral health to mood balance. Help us understand who YOUR end-consumer is and the benefit they will expect from your probiotic solution.
They have
O A global lifestyle approach
O A specific health condition or concern
Specify: ..........................................................................................................................................................................................................................................
Their priorities are(rank from 1 to 5, 1 being the top priority)
O Price
O Experienced efficacy of the product
O Product features / formulation
O Trust in the brand / the company
O Product documentation
Other, specify: ....................................................................................................................................................................................................................................
LALLEMAND HEALTH SOLUTIONS
COMPLETE SOLUTIONS. DESIGNER GUIDE.
YOU ARE UNIQUEHelp us be 100% relevant to YOUR needsOur solutions are customized to YOUR needs, so the better we know you from the start, the more likely our proposals will be to hit the mark. Over the past 80 years, LHS has developed partnerships of all kinds and we know for a fact that each and every partner is unique. Here are some of the key aspects we take into account when developing a new probiotic solution.
You have worked with probiotics for…
If you already have a line of probiotics, please provide all relevant details to see how our new solution would best fit.
AND SO SHOULD OUR SOLUTION BE
Business activity
O A supplier
Specify: ..........................................................
.............................................................................
O Other activityO A manufacturer
O Service provider, consultant O R&D
Industry
O Dietary Supplements
O Pharmaceutical products
O Food and beverage
Distribution channels
O Pharmacies
O Mail order, TV shop, internet
Specify: ......................................
.........................................................
O Health food stores
O Health professionals, dispensaries
Specify: ..........................................
.............................................................
O MLM
O Drugstores, supermarkets, food stores
Company size O 1-9 O 10-49 O 50-200 O 200-1000 O >1000
You plan to launch a new probiotic solution within the next...O 6 months O 6-12 months O > 1 year Specify: ........................................................................................................
Your objective is to launch O 1 formula O 2-3 formulas O A complete range
Under which registration status? Specify: .................................................................................................................................................
Specify: ...........................................................................................................................................................................................................................................................
Geographic coverage
O Worldwide O World region O Specific countries
YOU ARE
PROBIOTICS & YOU
Years0 1 2 3 4 5 10 15 20
WOULD YOU PREFERREADY-TO-MARKET DOCUMENTED FORMULAS?
Lacidofil®• 26 clinical studies: 13 in children / 13 in adults• Drug status in many countries with a pharmacovigilance program, for the prevention
and treatment of AAD and acute diarrhea in pediatric GI disease• Other GI applications: 2 studies on IBS, 2 on lactose intolerance, 5 on H. pylori
IBacilluS+ • 140+ clinical studies: acute diarrhea, AAD, ulcerative colitis and IBS (claim in Canada - NPN)
Lafti® B94• 4 clinical studies: 2 on infectious diarrhea in children, 2 in NEC (necrotizing
enterocolitis) on premature and CCHD (cyanotic congenital heart disease) infants• Selected from among 40 Bifidobacterium strains for its good synergy with
fibers (breakdown of FOS & inulin)
Lafti® L10 • 1 clinical study on IBS-like symptoms
Probio’Stick® • 1 clinical study on GI symptoms related to stress in active people
S. Boulardii • 100+ publications, the one and only probiotic yeast• Manufactured as an API, several grades available (ground, freeze dried with or
without lactose) in capsules, sachets, orodispersible sticks or as an ingredient for a Probiotic 2.0 formula
ProbioKid®
ProbioStim®• 5 clinical studies in children: 1 on winter infection, 1 on RTI (respiratory tract infection)
and wheezing, 2 safety studies in infants
Rosell® -71 • 1 clinical study: helps reduce the incidence of cold-like symptoms in stressed adults (claim in Canada – NPN)
Lafti® L10 • 3 clinical studies in active people: 2 in athletes, 1 in stressed students
Lacidofil® • 2 clinical studies in pregnant women
Fermalac® • 3 clinical studies as adjunctive treatment for vaginal infections
Cysbiotic® • Potent strain for women’s health combined with standardized cranberry
Probio’Stick® • 2 clinical studies for GI health and mood disorders
Probio’Stick®
• Pioneering R&D work on the brain-gut-axis, 4 mechanistic studies in vivo• 2 clinical studies with the first ever showing the positive effect of a probiotic on
psychological stress• The first and only probiotic with approved health claims in the gut-brain axis area
in Canada
Oralis SB• One of the most documented formulas in oral health • 4 clinical studies: 2 on caries and 2 on gingivitis with similar or better results
than standard mouthwash
�All our documented formulas exist in several dosage forms with stability data and complete registration dossier.
OR
WOULD YOU PREFERSPECIFIC CUSTOMIZED BLEND?
At Lallemand Health Solutions, we have focused a great deal of our research resources in documenting in vitro and in vivo the modes of action of our probiotic strains and in further corroborating their potency in humans with state of the art clinical studies. Today, we are proud to provide one of the largest portfolios of proprietary strains, with their potential areas of application. Relevance rates from + to +++ for the highest with available clinical studies.
LACTOBACILLI BIFIDOBACTERIA OTHERS
L. r
ham
nos
us
Ros
ell®
-11
L. h
elve
ticu
s R
osel
l®-5
2
L. c
asei
Ros
ell®
-215
L. r
ham
nos
us
Ros
ell®
-343
L. a
cid
oph
ilus
Ros
ell®
-418
L. p
lan
taru
m R
osel
l®-1
012
L. h
elve
ticu
s La
fti®
L10
L. p
arac
asei
Laf
ti® L
26
L. c
asei
HA
-108
L. r
ham
nos
us
HA
-111
L. b
revi
s H
A-1
12
L. r
ham
nos
us
HA
-114
L. s
aliv
ariu
s H
A-1
18
L. p
lan
taru
m H
A-1
19
L. a
cid
oph
ilus
HA
-122
L. h
elve
ticu
s H
A-1
28
L. f
erm
entu
m H
A-1
79
L. r
eute
ri H
A-1
88
L. p
arac
asei
HA
-196
B. i
nfa
nti
s R
osel
l®-3
3
B. b
reve
Ros
ell®
-70
B. b
ifid
um
Ros
ell®
-71
B. l
ong
um
Ros
ell®
-175
B. l
acti
s La
fti®
B94
B. i
nfa
nti
s H
A-1
16
B. b
reve
HA
-129
B. b
ifid
um
HA
-132
B. l
ong
um
HA
-135
B. l
acti
s H
A-1
94
S. b
oula
rdii
CN
CM
-107
9
Bac
illu
s su
bti
lis R
osel
l®-1
79
Bac
illu
s su
bti
lis H
A-1
24
En
tero
cocc
us
faec
ium
R
osel
l®-2
6
En
tero
cocc
us
faec
ium
H
A-1
27
Ped
ioco
ccu
s ac
idila
ctic
i R
osel
l®-1
001
Lact
obac
illu
s d
elb
ruec
kii
Ros
ell®
-187
Str
epto
cocc
us
ther
mop
hilu
s R
osel
l®-8
3
Str
epto
cocc
us
ther
mop
hilu
s H
A-1
10
Lact
ococ
cus
lact
is
Ros
ell®
-105
8
Lact
ococ
cus
lact
is H
A-1
36
Pro
pio
nib
acte
riu
m
freu
den
reic
hii
HA
-182
Pro
pio
nib
acte
riu
m
freu
den
reic
hii
HA
-273
GU
T
HEALTHY GUTLifestyle-induced gut discomfort, constipation, IBS
+++ +++ + +++ + + +++ + + + + + + + + + + + + + + + +++ ++ + + + + + +++ +++ + +++ + + + + + + + + +
DEFENSESAcute diarrhea, AAD, C. difficile and H. pylori infections
+++ +++ +++ + + + + +++ +++ + +++ + +++
CRITICAL CARE UC, NEC, Perioperative support +++ +++ ++ +++ +++ +++
IMM
UN
ITY
CHILDREN
Global immune support +++ +++ + +++ + + + + + +++ +++ +++ + +++
URT and GI infections +++ +++ +++ + + + +++ +++ +++ + +++
Atopic disorders ++ ++ ++ + + + +
ADULTS
Global immune support ++ ++ + +++ ++ + + ++ ++ +++ ++ +++
Common winter infections ++ ++ +++ + + ++ +++ +++
Active People ++ +++ ++ + ++ +++ ++ ++
SENIORS
Global immune support + ++ + ++ + + + + ++ ++ + +
Influenza and URTI + + ++ + + + ++ ++ +
Inflammaging ++ + + + + ++ + +
WO
ME
N'S
HE
ALT
H
FEMININE HEALTH
Bacterial vaginosis +++ +++ + ++ ++ + + + ++
Vulvovaginal candidiasis ++ ++ ++ + + + +
UTI ++ ++ + + + + ++
EVERYDAY HEALTH
GI discomfort +++ +++ ++ + + + ++ + + + +++ ++
Immunity + +++ +++ + + ++ +
Mood disorders ++ +++ + + + +++
AGE SPECIFIC HEALTH
Child-bearing age +++ +++ + ++ + + + ++ + + + +++ ++
Pregnancy +++ +++ ++ + + + + ++
Menopause + + + ++ + + + ++
BR
AIN
-GU
T
AX
IS
GUT
Stress-induced gut discomfort: abdominal pressure, flatulence, bloating
++ +++ + +++
MOOD Psychological stress resulting from life events ++ +++ +++ +++
OR
AL
H
EA
LTH
CARIES Destruction of the tooth enamel +++ +++ +++ ++ ++ + + + + ++ +++ + +
GINGIVITIS Inflammation of the gums +++ +++ +++ +++ + + ++ +++
HALITOSIS Bad breath + + + ++ ++
C ANDIDIASIS Yeast infection +++ + + + + +
Probiotic 2.0Optimal combination with S. boulardii
GI health P P P P P P P P P POral Health P P P P P P P P P
Other features
Halal grade available P P P P P P P P P P P P P P P P P P PNon Dairy P P P P P
Can be provided as API P P P P P
Probiocap technology P P P P
At Lallemand Health Solutions, we have focused a great deal of our research resources in documenting in vitro and in vivo the modes of action of our probiotic strains and in further corroborating their potency in humans with state of the art clinical studies. Today, we are proud to provide one of the largest portfolios of proprietary strains, with their potential areas of application. Relevance rates from + to +++ for the highest with available clinical studies.
LACTOBACILLI BIFIDOBACTERIA OTHERS
L. r
ham
nos
us
Ros
ell®
-11
L. h
elve
ticu
s R
osel
l®-5
2
L. c
asei
Ros
ell®
-215
L. r
ham
nos
us
Ros
ell®
-343
L. a
cid
oph
ilus
Ros
ell®
-418
L. p
lan
taru
m R
osel
l®-1
012
L. h
elve
ticu
s La
fti®
L10
L. p
arac
asei
Laf
ti® L
26
L. c
asei
HA
-108
L. r
ham
nos
us
HA
-111
L. b
revi
s H
A-1
12
L. r
ham
nos
us
HA
-114
L. s
aliv
ariu
s H
A-1
18
L. p
lan
taru
m H
A-1
19
L. a
cid
oph
ilus
HA
-122
L. h
elve
ticu
s H
A-1
28
L. f
erm
entu
m H
A-1
79
L. r
eute
ri H
A-1
88
L. p
arac
asei
HA
-196
B. i
nfa
nti
s R
osel
l®-3
3
B. b
reve
Ros
ell®
-70
B. b
ifid
um
Ros
ell®
-71
B. l
ong
um
Ros
ell®
-175
B. l
acti
s La
fti®
B94
B. i
nfa
nti
s H
A-1
16
B. b
reve
HA
-129
B. b
ifid
um
HA
-132
B. l
ong
um
HA
-135
B. l
acti
s H
A-1
94
S. b
oula
rdii
CN
CM
-107
9
Bac
illu
s su
bti
lis R
osel
l®-1
79
Bac
illu
s su
bti
lis H
A-1
24
En
tero
cocc
us
faec
ium
R
osel
l®-2
6
En
tero
cocc
us
faec
ium
H
A-1
27
Ped
ioco
ccu
s ac
idila
ctic
i R
osel
l®-1
001
Lact
obac
illu
s d
elb
ruec
kii
Ros
ell®
-187
Str
epto
cocc
us
ther
mop
hilu
s R
osel
l®-8
3
Str
epto
cocc
us
ther
mop
hilu
s H
A-1
10
Lact
ococ
cus
lact
is
Ros
ell®
-105
8
Lact
ococ
cus
lact
is H
A-1
36
Pro
pio
nib
acte
riu
m
freu
den
reic
hii
HA
-182
Pro
pio
nib
acte
riu
m
freu
den
reic
hii
HA
-273
GU
T
HEALTHY GUTLifestyle-induced gut discomfort, constipation, IBS
+++ +++ + +++ + + +++ + + + + + + + + + + + + + + + +++ ++ + + + + + +++ +++ + +++ + + + + + + + + +
DEFENSESAcute diarrhea, AAD, C. difficile and H. pylori infections
+++ +++ +++ + + + + +++ +++ + +++ + +++
CRITICAL CARE UC, NEC, Perioperative support +++ +++ ++ +++ +++ +++
IMM
UN
ITY
CHILDREN
Global immune support +++ +++ + +++ + + + + + +++ +++ +++ + +++
URT and GI infections +++ +++ +++ + + + +++ +++ +++ + +++
Atopic disorders ++ ++ ++ + + + +
ADULTS
Global immune support ++ ++ + +++ ++ + + ++ ++ +++ ++ +++
Common winter infections ++ ++ +++ + + ++ +++ +++
Active People ++ +++ ++ + ++ +++ ++ ++
SENIORS
Global immune support + ++ + ++ + + + + ++ ++ + +
Influenza and URTI + + ++ + + + ++ ++ +
Inflammaging ++ + + + + ++ + +
WO
ME
N'S
HE
ALT
H
FEMININE HEALTH
Bacterial vaginosis +++ +++ + ++ ++ + + + ++
Vulvovaginal candidiasis ++ ++ ++ + + + +
UTI ++ ++ + + + + ++
EVERYDAY HEALTH
GI discomfort +++ +++ ++ + + + ++ + + + +++ ++
Immunity + +++ +++ + + ++ +
Mood disorders ++ +++ + + + +++
AGE SPECIFIC HEALTH
Child-bearing age +++ +++ + ++ + + + ++ + + + +++ ++
Pregnancy +++ +++ ++ + + + + ++
Menopause + + + ++ + + + ++
BR
AIN
-GU
T
AX
IS
GUT
Stress-induced gut discomfort: abdominal pressure, flatulence, bloating
++ +++ + +++
MOOD Psychological stress resulting from life events ++ +++ +++ +++
OR
AL
H
EA
LTH
CARIES Destruction of the tooth enamel +++ +++ +++ ++ ++ + + + + ++ +++ + +
GINGIVITIS Inflammation of the gums +++ +++ +++ +++ + + ++ +++
HALITOSIS Bad breath + + + ++ ++
C ANDIDIASIS Yeast infection +++ + + + + +
Probiotic 2.0Optimal combination with S. boulardii
GI health P P P P P P P P P POral Health P P P P P P P P P
Other features
Halal grade available P P P P P P P P P P P P P P P P P P PNon Dairy P P P P P
Can be provided as API P P P P P
Probiocap technology P P P P
WHAT IF YOU COULD CHOOSE BOTH...? All our documented formulas
can be marketed as is… or AS AN INGREDIENT!
SOMEWHAT OVERWHELMED? Now that we know who you are and who you want to target for which benefit, let us guide you through our strains offer and funnel down for you the best strains and combinations with complementary effects to meet your needs. We will provide you all the way down the line with all the consolidated scientific documentation to support your launch.
YOU ARE ALMOST THERE!
IN NEED OF ANOTHER INGREDIENT?• Prebiotic• Vitamins• Minerals• Flavors• Others
We have selected for you a large range of ingredients with proven compatibility with our probiotic strains and blends, several backed by specific approved health claims (Selenium, Vitamin D, B Vitamins, Vitamin C...) to consolidate your formula positioning in your market. And if we do not yet have the one you want, the Lallemand applied research facility in Toulouse is there to assess feasibility before industrial scale up.
CHOOSE YOUR DOSAGE FORM• Powder• Orodispersible powder• Capsules • Enteric-coated capsules• Chewable tablets
CHOOSE YOUR PACKAGING OPTIONS• ACLAR blisters• Alu-alu blisters• Bottles• Sachets• SticksAnd what about a box? a leaflet maybe?
ANY OTHER SPECIFIC REQUIREMENT?
YOURPRODUCT
CERTIFIEDPRODUCTIONCENTRES
COMMERCIALOFFICES
SCIENTIFICRESEARCHCENTRES
Blagnac(France)
Montreal(Canada)
Toulouse(France)
Saint-Simon(France)
Vienna(Austria)
Mirabel(Canada)
Quebec(Canada)
Kuala Lumpur(Malaysia)
Beijing(China)
Birkerod(Denmark)
Czech Teschen(Czech Republic)
FOR MORE INFORMATION, PLEASE CONTACT: [email protected] or www.lallemand-health-solutions.comThis is business-to-business information not intended for the final consumer. It is based on our own research and development work and is, to the best of our knowledge, reliable. However, Lallemand does not assume any liability resulting from the use of its products, as conditions of use are beyond our control. The information provided should not be used as a substitute for any form of advice and in all cases, producers and marketers should check local regulatory requirements before use as different claims may be made depending on the regulations applicable in each country.
As a complete probiotic solution provider, we deliver probiotics of unparalleled quality.
At Lallemand Health Solutions, delivering the best probiotic strains and products is just the start; we make sure each client gets our utmost attention and each project benefits from a customized service plan. Ongoing support from our committed team is embedded in our values.
WE PROVIDE CUSTOMIZED SERVICES FROM REGULATORY TO MARKETINGOur team of regulatory experts maintains regular dialogue with authorities worldwide (e.g. Health Canada, US FDA, EFSA, TGA, ANVISA) for: Consultation as industry experts for the development of policies pertaining to probiotics
Successful registration/authorization of LHS probiotics Advocacy and regulatory intelligence in collaboration with trade associations and working groups
Our leading team of dedicated researchers, business development managers and marketers are available to our partners for scientific conferences, training seminars, continuous medical education, product launches or refresher courses for product line extensions.
FROM CONCEPTION TO COMMERCIALIZATION
years of know-how80+
countries60+
proprietary strains40+
formulas450+
QUALITY PROBIOTICS. COMPLETE SOLUTIONS.
CONTACT: [email protected]
WEBSITE: WWW.LALLEMAND-HEALTH-SOLUTIONS.COM
LALLEMANDHEALTH SOLUTIONS
PRO
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