general anatomy i of gastro-intestinal system · faces –buccae . roof: palatum . bottom:...
TRANSCRIPT
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General Anatomy of Gastro-IntesTinal
System
The Teeth,Oral CavityTongue, Salivary Glands,
Pharynx. Their Vessels and Innervation
Ivo Klepáček
GIT
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Digestive System:
Oral cavity (ectodermal origin)
The gut and ist derivatives (entodermal origin) is divided in four sections:
1. Pharyngeal gut or pharynx2. Foregut - esophagus, stomach, ¼ of duodenum, liver
and gallblader, pancreas3. Midgut – ¾ of duodenum, jejunum, ileum, colon
caecum, colon ascendens and 2/3 of colon transversum4. Hindgut – 1/3 of colon transversum, colon descendens,
colon sigmoideum, colon rectum, canalis analisGIT
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Function Structure Accessory glands
Digestio
Absorptio
Eliminatio
Glandulae salivariae
Pancreashepar
Cavum oris
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Primordium of the alimentarycanal (GastroInTestinal Canal)
● GIT develops together with respiratory system –systema gastropulmonale –
● it develops from the embryonal intestine (entoderm); lower respiratory structurses are splitted from intestine as a tracheobronchial pouch
● Ventral (head) intestine part is added to ectodermal pouch called stomodeum, caudal part of the intestine is added to ectodermal pouch called proctodeum
● Division of the alimentary tract: ● 1) oral ectodermal segment
2) main entodermal segment3) caudal ectodermal segment
● děivision of the main segment:● ventral gut (foregut – to biliary duct opening)
middle gut (midgut – to 2/3 colon) dorsal gut (hindgut – to upper part of the anal canal
tracheobronchial pouchGIT
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Alimentary tube (canal) -
general structure– tunica mucosa (mucous membrane)
1• epithelium• lamina propria mucosae (lymph tissue)• lamina muscularis mucosae
– tunica submucosa (submucouslayer) – vessels, nerves (plexus submucosus Meissneri)
– tunica muscularis (outer + inner muscular layer) – longitudinal, circular even plexiform; vessels, nerves (plexus myentericus Auerbachi)
– tunica serosa (serous layer) ortunica adventitia (fibrous layer) 14
salivary glands (glandulae salivariae)pancreasliver (hepar)gall bladder and bile ducts (vesica fellea, ductus choledochus)
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Maxilla and Mandible formation
48 day
35 day
14 week
28 day
Philtrum, Nasolacrimal
groove, Lacrimal sac,
Cheeks, Maxillae,
Nose
Frontonasal maxillary
et mandibular
processesGIT
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Development of the facialskeleton, formation of the nasal
and oral cavities● Primitive lips:
– week 6 - ectoderm ingrowth to mesenchyme in developing jaw – formation of the labiogingival lamina
● lamina splits into two layers separated by groove● central part of upper lip (known as a philtrum
develops from the intermaxillary segment)
Primitive oral cavity -stomodeum
depression lined by ectoderm and oropharyngeal membranemargines:
lower processes (mandibular) from the 1. pharyngeal arch -laterally of them upper processes (maxillary)of the 1. pharyngeal arch superiorly frontonasal process where nasal placodes appear (→pits, sacs and later are opened to primitive nasal cavity), medial and lateral nasal processes.
Week 5-6 – 10-14GIT
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Příčný rozštěp tvářeTransverse facial cleft
Šikmý rozštěp tvářeOblique facial cleft
Sulcus nasolacrimalis
Nude ductus nasolacrimalisGIT
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Cavitas oris Oral cavityrima oris – isthmus faucium
Dental arches divide cavity:
vestibulum orisandcavitas oris propria
borders:Ventrally: lips - labia oris laterally: faces – buccae roof: palatum bottom: mylohyoid m. + geniohyoid m., tongue (lingua, glossa)
Masticatory mucosa - Hard palate + gum (keratinized)Specialised mucosa - Tongue + papillary epitheliumLining mucosa - Bucca, soft palate (non-keratinized)
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Periodontium Innervation: free endings pain
Ruffini bodies tractionVater-Paccini bodies pressure, vibration
Mucosa - masticatoryspecialisedlining
Innervation: free, Paccini, Ruffini, Meissner pain, temperature, vibration, traction, pressurefree, Paccini, Ruffini, taste buds pain, temperature, vibration, traction, tastefree, Paccini, Meissner, Merkel temperature, vibration, pressure, pressure
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Labium + mentum
Lip Chin
The border between the lips and the surrounding skin is referred to as the vermilion.
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Labia
The skin of the lip, with three to five cellular layers, is very thin compared to face skin, which has up to 16 layers. Lip skin contains fewer melanocytes (pigment cells). Because of this, the blood vessels appear through the skin of the lips, which leads to their notable red coloring. The lip skin is not hairy, and does not have sweat glands or sebaceous glands. Therefore it does not have the usual protection layer of sweat and body oils which keep the skin smooth, inhibit pathogens, and regulate warmth. For these reasons, the lips dry out faster and become chapped more easily.
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http://en.wikipedia.org/wiki/Melanocytes�http://en.wikipedia.org/wiki/Blood_vessel�http://en.wikipedia.org/wiki/Sweat_gland�http://en.wikipedia.org/wiki/Sebaceous_gland�
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Outer keratinized epithelium is followed by internal multilayered cuboid and slowly keratinized (para-keratinization) epithelium lamina propria mucosae submucous layer with small salivary and mucous glands (in soft palate)
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vascular and nervous suply of the face and lipsA. facialis a. labialis sup.& inf.A. temporalis superficialis a. transversa facieiA. maxillaris a. buccalis
V. facialisV. transversa faciei v. retromandibularis
v. faciei profunda pl. pterygoideus
Ln. submentales, submandibulares
Inervationsensitive: n.V/2 n.infraorbitalis, zygomaticus
V/3 n.mentalis, buccalismotor: n.VII
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OROFACIAL SYSTEM(Maxilomandibular, maxilofacial, chewing, stomatognathic)
Jaws, hyoid bone, face bones, temporomandibular joints, teeth, periodontium, face soft tissues lips,, oral cavity organs, mucous membrane of the oral cavity, salivary glands, pharynx, tonsills,
vessels, nerves, receptors
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Palatum durum, Palatum molle
Hard palateSoft palate
PremaxillaMaxillaOs palatinum
Papilla, rugae (folds), pits (foveolae)Lines (crests)
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Palate – surface features
Incisive papilla
Rugae palatinae
Median rapheGIT
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Palatum palateNeonatusnewborn
Senilisold
pink – extent of the total tooth prosthesisdash lines – areae where prosthesis pressure on the palate has to be controlled
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Palatal relief with rugae, foveolae and incisal papila
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Stěna jícnu a –a.+v. +n. palatinus majorgreater palatine artery, vein, nerve
b –sulcus palatinus majorgreater palatine groove
c –glandulae palatinaepalatal glands
d –a.+v.+n. palatinus minorlesser palatine artery, vein, nerve
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Stěna jícnu Tunica mucosa – plicae transversae – multilayered poorly keratinized epithelium
Tunica submucosaCan be found only inside palatal grooves
Tunica muscularis– found in the soft palate as intrinsic and extrinsic muscular structuresTunica adventitiaIn the hard palate there is periosteum; inside soft palatum there is a aponeurosis in the midline
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OROFACIAL SYSTEM(Maxilomandibular, maxilofacial, chewing, stomatognathic)
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OROFACIAL SYSTEM(Maxilomandibular, maxilofacial, chewing, stomatognathic)
Jaws, hyoid bone, face bones, temporomandibular joints, teeth, periodontium, face soft tissues lips,, oral cavity organs, mucous membrane of the oral cavity, salivary glands, pharynx, tonsills,
vessels, nerves, receptors
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Soft palate
– dorsal view
– ventral view
mm. levatores veli palatinitensores veli palatinipalatoglossipalatopharyngeiuvularesDots – line between ventral
and dorsal (more moveable) parts of the soft palate GIT
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Chrápání Snoring
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Separation of the nasal and oral cavities– Ectoderm plate, mesoderm– Primary palate : intermaxillary
segmentSecondary palate (6.-8. week)
– Horizontalization and fusion of the palatine shelves
– Mesenchymal nasal septum develops from the frontal process
Primary palate Secondary palateGIT
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Secondary palate formation
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UnilateralBilateral
VentralDorsal
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Tongue Lingua Glossa
Mobile musculoepithelial organ;Located in the oral cavity and
pharynxapexcorpus (body)
dorsumfacies inferior
radix (root)margo (margin)sulcus (groove)
terminalismedianus (midline)
foramen caecumtonsilla lingualis
Week 6
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Palatoglossal archPalatopharyngeal arch
Triangular fold (plica) (there is r. tonsillaris)
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Papillae filiformesfungiformesvallataefoliatae
Foramen caecum
Filiformes
Fungiformes
Vallatae
Foliatae
Calliculus gustatorius
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salty
sour
sweet
bitterGIT
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Inervation motor:n. XII, (xm.palatoglossus)
sensitivesensory
vegetative:parasympathetic
ggl. submandibular
sympathetic
plexus lingualis
x
Ix
V3GIT
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Bottom of the oral cavityfrenulum linguae, sublingual fold, carunculae
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Spodina dutiny ústnífrenulumlinguae, plicasublingualis, carunculae
Canalis paralingualis = mezi m. hyoglossus a m. genioglossus
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mm. geniohyoidei
gl. sublingualis
gl. submandibularis
caruncula sublingualis
ductus Whartoni
nervus lingualis
a. lingualis et m.
hyoglossus
Septum linguae –
sparse tissue
Floor of the oral cavity
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Floor of the oral cavity
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Intrinsic lingual musclesalter lingual shape
Superior and inferior longitudinal, transverse, vertical musclesGIT
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StyloglossusPalatoglossus
HyoglossusGenioglossus
Palatoglossus
Extrinsic lingual musclesalter the position of the tongueGIT
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Relation between
tongue and styloid septum
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Arteriae
Arteries
Venae
VeinsGIT
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Lymph outflow from tongue
Finally to the deep nodes
jugulodigastric node
juguloomohyoid node
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Glandulae oris glandulae salivariae majores
– gl. parotis– gl. sublingualis– gl. submandibularis
glandulae salivariae minores - labiales, buccales, molares, palatinae, linguales /Nuhni/
● Surrounded by capsules (dense connective tissue) → septae– Secretory part – serous and mucinous cells, myoepithelial
(basket) cells– Glandular ducts
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Salivary gland
scheme of the ductsGIT
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Mucous and serous lingual glands
Ebner gl.serous
Weber gl.mucinous
Anterior Lingual gl.GIT
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Glandula parotisSuperficial partDeep part (processus pharyngeusSerous tissueDuctus parotideus (of Stensen)GIT
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Superficial and deep part of parotid gland can be separated from each other in level where facial plexus lies; there is also a thin layer of the sparse connective tissue
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Glandula submandibularis
Mucoserous tissueDuctus submandibularis (of Wharton)
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Glandula sublingualis
Seromucinous tissueDuctus sublingualis major et minores (of Santorinus)
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1:1S
3:21:3
Relation betweenserous and mucous
parts
Lingual nerve crosses submandibular duct in the level of dorsal margine of mylohyoid muscle
Glandula parotideaSublingualisSublingualis anteriorSubmandibularisGIT
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Hltan Pharynx rozčlenění
Nasopharynx (epi-)Oropharynx (meso-)Laryngopharynx (hypo-)
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Development of pharynx● Cranial part of the ventral gut● 6 pharyngeal arches (gills, branchial arches)● Pharyngeal pouchesGIT
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Piriform recess
Pharyngeal recess
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Pharynx - muscles● raphe pharyngis, fascia pharyngobasilaris, Luschka s
space● mm. constrictores /3/
– m.c. superior – 4 parts – origin at skull /3/ and tongue /1/– m.c. medius – 3 parts – origin at hyoid bone– m.c. inferior – 2 parts – origin at laryngeal cartilages
● mm. levatores /3/– m. palatopharygeus (part of soft palate muscles, mounting
of the palatopharyngeal arch)– m. salpingopharyngeus– m. stylopharyngeus (!exception! – innervated by n.IX !)
● innervation: plexus pharyngeus z n. X- except m. stylopharyngeus /n. IX /
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* m. stylopharyngeus
** Nervus et vasa laryngea superiora CN X
Piriform recessRecessus piriformis(piriform recess, pouch)is bordered by aryepiglottic fold and pharyngoepiglottic fold
Nervus can be irritated through difficult swallowing or tumor growth
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Superior constrictor SC1 Pars pterygopharyngea2 Pars buccopharyngea3 Pars mylopharyngea4 Pars glossopharyngea
Medius constrictor MC5 Pars chondropharyngea6 Pars ceratopharyngea7 Pars desmopharyngea
Inferior constrictor IC8 Pars thyropharyngea9 Pars cricopharyngea
12
34
567
8
9
SC: raphe – mandible and hamulusMC: raphe – hyoid bone and stylohyoid lig.IC: raphe – cricoid and thyroid cartilages and cricothyroid lig.
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a – musculus constrictor pharyngis inferior, b –membrana thyreoidea, c – ligamentum thyreoideum medianum, d – os hyoideum, e –membrana hyoepiglottica, f – arcus palatopharyngeus, g – raphe buccopharyngea, h - arcus palatoglossus, i – musculus tensor veli palatini, j – musculus levator veli palatini, k –ústí tuba Eustachií (Eustachovy trubice), l –tonsilla tubaria, m – tonsilla nasopharyngea, n –membrana pharyngobasillaris; musculus constrictor pharyngis superior: o – pars pterygopharyngea, p – pars buccopharyngea, q – pars mylopharyngea, r – pars glossopharyngea; musculus constrictor pharyngis medius: s – pars desmopharyngea, t –pars chondropharyngea et ceratopharyngea, u –musculus stylopharyngeus, v – musculus stylohyoideus, w - vasa laryngea superiora et nervus laryngeus superior, x – musculus constrictor pharyngis inferior, y - musculus cricothyreoideus, z – conus elasticus (ligamentum thyreoideum medianum), * -spatium preepiglotticum
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Pharynx – blood supply
● Arteries: a. carotis ext.
– a. pharyngea ascendens
– a. facialis a. palatina ascendens
– a. lingualis rr. dorsales linguae
– a. maxillaris a. palatina major, a. canalis pterygoidei, r. pharyngeus
● Veins: plexus (venosus) pharyngeus v. facialis v. jugularis int.
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Jugulodigastricjuguloomohyoid
deep cervical lymph nodes
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Spaces surrounding pharynx
● lamina prevertebralis fasciae cervicalis 8 +
● septum styloideum 11
● spatium retropharyngeum 4
● spatium paraviscerale● spatium parapharyngeum
1. sp. prestyloideum 22. sp. retrostyloideum 3GIT
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Esophageal (Zenker s) diverticleGIT
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Tonsillar lymph circle of Waldeyer
Heinrich Wilhelm Gottfried Waldeyer
1836-1921
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Anulus lymphoideus pharyngis /Waldeyeri/
První ochranná bariéra organismu
Tonsilla pharyngea /1/● Tonsilla tubaria /Gerlachi/ /2/● Tonsilla palatina /2/● Tonsilla lingualis /1/
Heinrich Wilhelm Gottfried von Waldeyer-Hartz(1836 – 1921), German anatomist
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Waldeyer lymph circle
t.pharyngea
t.tubaria
t.palatina
t.lingualis
ln.retropharyngeal nodes
Wood node
ln.jugulodigastricus(Küttner node)
ln.cervicales profundi
- Lower group
3 protective barriers
ln.submentales &submandibulares
ln.juguloomohyoideus
tongueGIT
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Incomplete capsuleOnly efferent lymph vesselsModified epithelium in crypts (lymphoepithel or FAE follicle-associated epithelium)Intraepithelial vascularizationFree, T, B lymphocytes,active immunocompetitive cells, macrophages, Langerhans cells, fibrous stroma
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tonsillectomy
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Sources:Schumacher, G.H.: Anatomie für Stomatologen, Band 1,
Johann Ambrosius Barth Leipzig 1984Tillmann,B.: Atlas der Anatomie,
Springer 2004McKinnon,P and Morris J: Oxford Textbook of Functional Anatomy, Vol. 3. Oxford University Press 1990Rogers AW: Textbook of Anatomy,
Churchill Livingstone, Edinburgh 1992Schünke M: Topographie und Funktion des Bewegungssystems,
Thieme, Stuttgart 2000Ivo Klepáček, J. Mazánek a kol.: Klinická anatomie ve stomatologii, Grada 2002Vlastní archiv
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Pharynx – Lymph and Nerves● Lymph: n.l. retropharyngei, n.l. paratracheales n.l. cervicales profundi
● Nerves: form plexus pharyngeus– motor n.X (plexus pharyngeus), n.IX (m.
stylopharyngeus)– sensory n.X + n.IX (plexus pharyngeus), n.V2 (n.
pharyngeus for nasopharynx)– autonomic n.X (plexus pharyngeus) =
parasympathetic, rr. laryngopharyngei = sympatheticGIT
Snímek číslo 1Snímek číslo 2Snímek číslo 3Primordium of the alimentary canal (GastroInTestinal Canal)Alimentary tube (canal) - general structure Maxilla and Mandible formationDevelopment of the facial skeleton, formation of the nasal and oral cavitiesSnímek číslo 9Cavitas oris Oral cavitySnímek číslo 11Snímek číslo 12Snímek číslo 13Snímek číslo 14Snímek číslo 15Snímek číslo 16Snímek číslo 17Snímek číslo 18Snímek číslo 19Palate – surface featuresPalatum palate Snímek číslo 22Stěna jícnu Stěna jícnu Snímek číslo 25Snímek číslo 26Snímek číslo 27Snímek číslo 28Snímek číslo 30Separation of the nasal and oral cavitiesSnímek číslo 32Snímek číslo 33Tongue Lingua GlossaPalatoglossal arch�Palatopharyngeal arch�Snímek číslo 36Snímek číslo 37Snímek číslo 38Snímek číslo 40Snímek číslo 41Snímek číslo 42Floor of the oral cavitySnímek číslo 44Snímek číslo 45Snímek číslo 46Snímek číslo 47Snímek číslo 48Glandulae orisSalivary gland scheme of the ductsSnímek číslo 51Snímek číslo 52Snímek číslo 53Snímek číslo 54Snímek číslo 55Snímek číslo 56Snímek číslo 57Snímek číslo 58Snímek číslo 59Development of pharynxPiriform recessPharynx - musclesSnímek číslo 63Snímek číslo 64Snímek číslo 65Pharynx – blood supplyJugulodigastric�juguloomohyoid��deep cervical lymph nodesSpaces surrounding pharynxSnímek číslo 69Snímek číslo 70Anulus lymphoideus pharyngis /Waldeyeri/Waldeyer lymph circleSnímek číslo 73Snímek číslo 74Snímek číslo 75Snímek číslo 76Pharynx – Lymph and Nerves