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Life Sciences springer.com/NEWSonline

98

B. Biswal, Sambalpur University, India; K. Krupinska, University of Kiel, Germany; U. C. Biswal, Sambalpur University, India (Eds)

Plastid Development in Leaves during Growth and SenescenceContents Preface.- Part I: General Aspects of Chloroplast Development.- 1. The Dynamic Role of Chloro-plasts in Integrating Plant Growth and Develop-ment; Karin Krupinska et al.- 2. Chloroplast Development: Time, Dissipative Structure and Fluctuations; Mukesh K. Raval et al.- Part II: Chlo-roplast Biogenesis During Leaf Development.- 3. Etioplasts and their Significance in Chloroplast Biogenesis; Katalin Solymosi, Henrik Aronsson.- 4. The Biogenesis of the Thylakoid Membrane – Photosystem II, a Case Study; Karin Meierhoff, Peter Westhoff.- 5. Organization and Assembly of Photosystem I; Yukako Hihara, Kintake Sonoike.- 6. Rubisco Assembly - a Research Memoir; Harry Roy.- 7. Glycerolipid Biosynthesis and Chloroplast Biogenesis; Maryse Block et al.- 8. Chloroplasts Contact with the Endoplasmatic Reticulum and Lipid Trafficking; Mats X. Andersson.- 9. Stromule Formation; John C. Gray.- Part III: The Plastid Genome and its Expression during Chloroplast Development.- 10. Dynamic Features of the Plastid Genome and its Transcriptional Control in Plastid Development; Kengo Kanamaru, Mamoru Sugita.- 11. Development-Dependent Changes in the Amount and Structural Organization of Plas-tid DNA; Karsten Liere, Thomas Börner.- 12. The Ins and Outs of Chloroplast Protein Transport; Qihua Ling et al.- Part IV: Leaf Senescence and Chloroplast Dismantling.- 13. Defining Senes-cence and Death in Photosynthetic Tissues; Larry D. Nooden.- 14. Ultrastructural Analyses of Se-nescence Associated Dismantling of Chloroplasts Revisited; Maria Mulisch, Karin Krupinska. [...]

Fields of interestPlant Sciences; Plant Physiology; Plant Biochem-istry

Target groupsResearch

Discount groupProfessional Non-Medical

Due December 2012

2013. Approx. 700 p. 124 illus., 35 in color. (Advances in Photosynthesis and Respiration, Volume 36) Hardcover7 $499.00ISBN 978-94-007-5723-3

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N. Boopathi, Tamil Nadu Agricultural University,Tamil Nadu, India

Genetic Mapping and Marker Assisted SelectionBasics, Practice and Benefits

Genetic mapping and marker assisted selection (MAS) is considered as one of the major tools in genetic improvement of crop plants in this genomics era. This book describes basics in link-age mapping, step-by-step procedure to perform MAS, achievements made so far in different crops, and limitations and prospects of MAS in plant breeding. It summarizes all this in a simple but comprehensive mode using suitable examples so as to explain the concept and its historical devel-opments.

Features 7 Gives information on the genetic make-up of the physiological, morphological and behavioural traits of plants 7 Informs how disease resistant varieties can be developed using genetic mark-ers 7 Discusses in detail the acceleration of the breeding process using markers

Contents 1.Germplasm Characterization: Utilizing the Un-derexploited Resources.- 2. Mapping Population Development .- 3.Genotyping.- 4. Linkage Map Construction.- 5. Phenotyping.- 6. QTL Identifica-tion.- 7. Fine Mapping.- 8. Marker Assisted Selec-tions.- 9. Success Stories in MAS.- 10. Advances in MAS toward genetically improved crop plants.- 11. Recent advances in MAS in major crops.- 12. Future perspectives in MAS.

Fields of interestPlant Sciences; Plant Breeding/Biotechnology; Plant Genetics & Genomics



Due February 2013

2013. VII, 370 p. 27 illus., 9 in color. Hardcover7 $189.00ISBN 978-81-322-0957-7

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M. A. Borowitzka, N. R. Moheimani, Murdoch University, WA, Australia (Eds)

Algae for Biofuels and EnergyMicroalgae are one of the most studied potential sources of biofuels and bioenergy. This book cov-ers the key steps in the production of renewable biofuels from microalgae - strain selection, culture systems, inorganic carbon utilisation, lipid metab-olism and quality, hydrogen production, genetic engineering, biomass harvesting, extraction.

Features 7 Focuses on the major aspects of renewable biofuel production from microalgae 7 Includes practical applications on laboratory level and larger scale 7 Written by key experts in the field of applied phycology

Contents 1. Energy from microalgae: A short history.- 2. Algal lipids and their metabolism.- 3. Hydrog-enases, nitrogenases, anoxia, and H2 production in water-oxidizing phototrophs.- 4. Species and strain selection.- 5. Limits to phototrophic growth in dense culture: CO2 supply and light.- 6. Genetic engineering to improve algal biofuels production.- 7. Photobioreactors for microalgae biofuel produc-tion.- 8. Open pond culture systems.- 9. Waste-water treatment and algal biofuel production.- 10. Harvesting, thickening and dewatering microalgae biomass.- 11. Solvent extraction for microalgae lipids.- 12. Production and properties of biodiesel from algal oils.- 13. Energy considerations of photobioreactors.- 14. Greenhouse gas balance and algae-based biodiesel.- 15. Techno-economic modelling for biofuels from microalgae.- 16. Basic methods for measuring algae growth and composition.

Fields of interestPlant Sciences; Plant Breeding/Biotechnology; Renewable and Green Energy



Due December 2012

2013. X, 210 p. 96 illus., 27 in color. (Developments in Applied Phycology, Volume 5) Hardcover7 $189.00ISBN 978-94-007-5478-2

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www.springer.com/978-94-007-5723-3



News 11/2012 Life Sciences

99

S. Deb, S. P. Deb, Virginia Commonwealth University, Richmond, VA, USA (Eds)

p53 ProtocolsThe second edition of p53 Protocols expands upon the first edition with progress in p53 research since the publication of the first edition.

Features 7 Fully updated with cutting-edge additions to the popular first edition 7 Provides step-by-step reproducible laboratory protocols 7 Contains tips on troubleshooting and avoiding known pitfalls

Contents Detecting and Quantifying p53 Isoforms at mRNA Level in Cell Lines and Tissues.- Detecting p53 Isoforms at Protein Level.- Autophagy, Senes-cence and Apoptosis.- p53 and Cell Cycle Effects after DNA Damage.- p53 Ubiquitination and Proteasomal Degradation.-Identification of p53 in Mitochondria.-Identification of Novel Mutant p53 Interacting Proteins by Proteomic Analysis.-Identification of Small Molecules Affecting p53-MDM2/MDMX Interaction by Fluorescence Polarization.- Determine the Effect of p53 on Chemosensitivity.-Measurement of Chemosensi-tivity and Growth Rate in p53 Expressing Cells.- Mutant p53 in Cell Adhesion and Motility.- Use of the DNA Fiber Spreading Technique to Detect the Effects of Mutant p53 on DNA Replication.- Gen-eration of p53-deficient Induced Pluripotent Stem Cells (iPS) from Mouse Embryo Fibroblasts.- p53 Actions on MicroRNA Expression and Matura-tion Pathway.- Isolation and Characterization of Murine Multipotent Lung Stem Cells.- Generation of p53 Knock-down Cell Lines.-ChIP for Identifi-cation of p53 Responsive DNA Promoters.- ChIP-on-chip to Identify Mutant p53 Targets.- ChIP Se-quencing to Identify p53 Targets.- The p53-Mdm2 Loop: A Critical Juncture of Stress Response.

Field of interestProtein Science

Target groupsProfessional/practitioner


Due November 2012

2nd ed. 2013. XVI, 260 p. 51 illus., 33 in color. (Methods in Molecular Biology, Volume 962) Hardcover7 $119.00ISBN 978-1-62703-235-3

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S. Divakar, Central Food Technological Research Institute, Mysore, India

Enzymatic TransformationTransformations using enzymes have been exten-sively investigated in the last two decades and the results promise great potential for this growing field, especially in the area of synthetic organic chemistry mainly due to of its many advantages. Accordingly, this book has attempted to bring out the advantages of using enzymes involving com-plex underivatized and unprotected substrates in non-polar media under homogenous and hetero-geneous reaction conditions. Merits and demerits of using enzymes in terms of yields and selectivity/specificity are presented without any prejudice.

Features 7 This book brings out the practical difficulties in carrying out enzyme catalyzed reactions in non-polar solvent 7 It outlines various strategies adopted to enhance especially yield and selectivity in such reactions 7 Diversity of underivatized multi-functional substrates employed to highlight the difficulties involved in terms of the extent of success achieved in such reactions

Contents Preface.- Abstract of Chapters.- Introduction.- Glycosidases.- Lipases.-Enzymatic Esterification of Compounds Possessing Multifunctional Hydroxyl and Carboxyl Groups.- Enzymatic Polymeriza-tion.- Lipase Catalyzed Preparation of Aminoacyl Esters of Carbohydrates.- Enzymatic Glycosyl-ation of Alcohols.- Glycosylation of Some Selected Phenols and Vitamins.- Glycosylation of Phenols and Vitamins.– An Overview.- Kinetics of Some Selected Enzyme Catalyzed Reactions in Organic Solvents.- ACE Inhibition and Antioxidant Ac-tivities of Enzymatically Synthesized Aminoacyl Esters And Glycosides.

Fields of interestBiochemistry, general; Protein Science; Chemis-try/Food Science, general



Due January 2013

2013. X, 411 p. 93 illus., 12 in color. Hardcover7 $189.00ISBN 978-81-322-0872-3

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R. J. Dufault, Clemson University, Charleston, SC, USA

Stalking the Wild SweetgrassDomestication and Horticulture of the Grass Used in African-American Coiled Basketry

Stalking the Wild Sweetgrass: Domestication and Horticulture of the Grass Used in African-American Coiled Basketry is concerned with the historical domestication of sweetgrass, the main construction/structural grass used in the three century old African-American tradition of coiled basketry in South Carolina.

Features 7 There is no other book available on this subject matter 7 Provides a real example of domesticat-ing a crop from the wild to cultivation and an ancient art form that is dependent on positive re-sults 7 Provides knowledge of the horticulture of an extremely important wild plant and an example of the perils of plant- and people-based research and experimentation.

Contents Introduction.- The beginnings of change.- My time to get involved.- Getting to the grass roots of cultivation.- Getting more involved.- Sweetgrass Utopia in the Southeast – Little St. Simon’s Island.- Getting to know the basketmakers.- Sweetgrass Culture Workshop Oct. 24, 1992.- The concept of large scale sweetgrass plantations.- 2nd Site of large scale sweetgrass plantings – McLeod Planta-tion, James Island.- 3rd Site of large scale sweet-grass plantings – Dill Sanctuary, James Island.- Alternative ways to access sweetgrass.- Sweetgrass biology.- Sweetgrass horticulture -environmental considerations.- Seedling cultural practices.- Field production practices.- Concluding thoughts.- Af-terthoughts.

Fields of interestPlant Sciences; Plant Systematics/Taxonomy/ Biogeography; Plant Ecology



Due November 2012

2013. IX, 113 p. 59 illus., 55 in color. (SpringerBriefs in Plant Science) Softcover7 $49.95ISBN 978-1-4614-5902-6

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100

M. L. East, M. Dehnhard, Institute for Zoo and Wildlife Research, Berlin, Germany (Eds)

Chemical Signals in Vertebrates 12Contents Part 1. Olfaction: Receptors and Neural Process-ing.- 1. Neural Substrate to Associate Odorants and Pheromones: Convergence of Projections from the Main and Accessory Olfactory Bulbs in Mice.- 2. Acceleration of Puberty Onset in Female Mice by Male Urinary Odours: Chemosensory, Physiological and Neuroendocrine Mechanisms.- 3. The Recessus Olfactorius: A Cryptic Olfactory Organ of Anuran Amphibians.- Part 2 Mother-Offspring Communication.- 4. Smell, Suck, Sur-vive: Chemical Signals and Suckling in the Rabbit, Cat and Dog.- 5. Neonatal Recognition in Sheep.- 6. Suckling Odours in Rats and Mice: Biological Substrates that Guide Newborns to the Nipple.- 7. The Role of Olfaction at Birth in Marsupial and Monotreme Mammals.- Part 3. Pheromones and Social Organisation.- 8. Individual Variation in Pheromone Isoform Ratios of the Red-Legged Salamander, Plethodon shermani.- 9. Rodent Urinary Proteins: Genetic Identity Signals and Pheromones.- 10 From Exploration to Selec-tive Information Gathering: The Development of Chemosensory Investigation in Male African El-ephants (Loxodonta africana).- Part 4. Odour pro-files and social organisation.- 11. Sex Differences in Olfactory Behaviours Reflect the Importance of Scent Marking for Social Integration in Adult Females and Competition between Reproductively Active Males in the Spotted Hyena.- 12. Is the Per-ception of Dietary Odour Cues Linked to Sexual Selection in Humans?.- 13. Hemiterpenoids and Pyrazines in the Odoriferous Urine of the Maned Wolf (Chrysocyon brachyurus).- 14. The Perfume-Body Odour Complex: An Insightful Model for Culture-Gene Coevolution?. [...]

Fields of interestAnimal Ecology; Animal Biochemistry; Ecology

Target groupsGraduate


Due January 2013

2013. XV, 597 p. 93 illus., 26 in color. Hardcover7 $209.00ISBN 978-1-4614-5926-2

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L. Eichinger, University of Cologne, Germany; F. Rivero (Eds)

Dictyostelium discoideum ProtocolsContents The Amoebozoa.- The Model Organism Dictyo-stelium discoideum.-Comparative Genomics of the Dictyostelids.- One Stop Shop for Everything Dictyostelium: DictyBase and the Dicty Stock Center in 2012.- Fluorescent Reporters and Meth-ods to Analyze Fluorescent Signals.-Collection and Cultivation of Dictyostelids from the Wild.-Identification and Verification of microRNAs by High-throughput Sequencing.- Transcriptional Profiling of Dictyostelium with RNA Sequenc-ing.- Analysis of Chromatin Organization by Deep Sequencing Technologies.- Pharmacogenetics of Resistance to Cisplatin and Other Anti-cancer Drugs and the Role of Sphingolipid Metabolism.-N-glycomic and –Glycoproteomic Studies in the Social Amoebae.-Measuring Cheating, Fitness, and Segregation in D. discoideum.-The Ap-plication of the Cre-loxP System for Generating Multiple Knock-Out and Knock-In Targeted Loci.- Extrachromosomal Inducible Expres-sion.- Isolation of Dictyostelium Nuclei for Light and Electron Microscopy.- Investigation of DNA Repair Pathway Activity.- Transcript Localization in D. discoideum Cells by RNA FISH.- Analysis of Mitochondrial Gene Expression.- Mitochondrial Respiratory Complex Function and the Pheno-typic Consequences of Dysfunction.- Micropipette Aspiration for Studying Cellular Mechanosensory Responses and Mechanics .- Quantitative Analysis of Phagocytosis and Phagosome Maturation.- Set-ting Up and Monitoring an Infection of Dictyo-stelium discoideum with Mycobacteria.- Isolation of Pathogen-containing Vacuoles.- Immuno-magnetic Purification of Fluorescent Legionella-containing Vacuoles. [...]

Fields of interestMicrobiology; Eukaryotic Microbiology



Due January 2013

2nd ed. 2013. 500 p. 109 illus., 33 in color. (Methods in Molecular Biology, Volume 983) Hardcover7 $139.00ISBN 978-1-62703-301-5

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J. Gescher, Karlsruhe Institute of Technology, Karlsruhe, Germany; A. Kappler, Eberhard-Karls-University Tuebingen, Center for Applied Geoscience (ZAG), Tuebingen, Germany (Eds)

Microbial Metal RespirationFrom Geochemistry to Potential Applications

Microbes can respire on metals. This seemingly simple finding is one of the major discoveries that were made in the field of microbiology in the last few decades. The importance of this observation is evident. Metals are highly abundant on our planet.

Features 7 This book is a timely and comprehensive inter-disciplinary review of our current understanding of respiratory metal reduction 7 Elucidates the different principles that have to be regarded to ful-ly understand microbial metal reduction 7 Writ-ten by authors which belong to the forefront of researchers it is intended to be a resource - but not only - for geochemists, microbiologists, biochem-ists and environmental engineers

Contents Minerals and Aqueous Species of Iron and Man-ganese as Reactants and Products of Microbial Metal Respiration.- Energetic and Molecular Constraints on the Mechanism of Environmental Fe(III) Reduction by Geobacter.- Biochemistry of Extracellular Respiration in Shewanella oneiden-sis.- On the Role of Endogenous Electron Shuttles in Extracellular Electron Transfer.- Humic Sub-stances and Extracellular Electron Transfer.- Metal Reducers und Reduction Targets. A Short Survey about the Distribution of Dissimilatory Metal Reducers and the Multitude of Terminal Electron Acceptors.- Metal Reduction as a Tool in Bioreme-diation Processes.- Dissimilatory Metal Reducers Producing Electricity.- Microbial Fuel Cells.

Fields of interestMicrobiology; Biogeosciences; Microbial Ecology



Due October 2012

2012. IX, 232 p. 47 illus., 14 in color. Hardcover7 $189.00ISBN 978-3-642-32866-4

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101

S. B. Hake, Adolf-Butenandt Institue, Muchen, Germany; C. Janzen, University of Würzburg, Germany (Eds)

Protein AcetylationMethods and Protocols

Contents Validation of Protein Acetylation by Mass Spectrometry.- Application of the CIRAD Mass Spectrometry Approach for Lysine Acetylation Site Discovery.- Application of the MIDAS Approach for Analysis of Lysine Acetylation Sites.- Applica-tion of High Content Biology to Yield Quantita-tive Spatial Proteomic Information on Protein Acetylations.- Towards the N-terminal Acetylome: An N-terminal Acetylated Peptide Enrich-ment Method Using CNBr-Activated Sepharose Resin.- Identification and Analysis of O-acetylated Sialoglycoproteins.- HPLC-based Quantification of in vitro N-terminal Acetylation.- Separation and Purification of Multiply Acetylated Proteins using Cation-exchange Chromatography.- In-gel N-acetylation for the Quantification of the Degree of Protein in vivo N-terminal Acetylation.- Computational Prediction of Lysine Acetylation Proteome-wide.- Generation and Characterization of Pan-specific Anti-acetyllysine Antibody.- Using Functional Proteome Microarrays to Study Protein Lysine Acetylation.- Quantitation of Nucleosome Acetylation and other Histone Post-Translational Modifications Using Microscale NU-ELISA.- Pre-paring Semisynthetic and Fully Synthetic Histones H3 and H4 to Modify the Nucleosome Core.- Production of Amino-terminally Acetylated Recombinant Proteins in E. coli.- Identification of Lysine Acetyltransferase Substrates using Bioor-thogonal Chemical Proteomics.- Non-radioactive in-vitro Assays for Histone Deacetylases.- The Fluorescence-Based Acetylation Assay Using Thiol-Sensitive Probes. [...]

Field of interestProtein Science



Due January 2013

2013. 250 p. 49 illus., 10 in color. (Methods in Molecular Biology, Volume 981) Hardcover7 $119.00ISBN 978-1-62703-304-6

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U. Jakob, University of Michigan; Ann Arbor; MI; USA; D. Reichmann, University of Michigan;Ann Arbor;MI;USA (Eds)

Oxidative Stress and Redox RegulationContents Chapter 1 The Chemistry of Thiol Oxidation and Detection.- Chapter 2 Radical Scavenging by Thiols and the Fate of Thiyl Radicals.- Chapter 3 Redox Homeostasis.- Chapter 4 Sulfenic Acids and Peroxiredoxins in Oxidant Defense and Signal-ing.- Chapter 5 Fluorescent imaging of redox spe-cies in multicellular organisms.- Chapter 6 Redox Proteomics.- Chapter 7 Computational redox biol-ogy: methods and applications.- Chapter 8 Redox regulation in plants: Glutathione and “Redoxin” related families.- Chapter 9 Prokaryotic Redox Switches.- Chapter 10 Combating Oxidative/Nitrosative Stress with Electrophilic Counterat-tack Strategies.- Chapter 11 Reactive Oxygen Species, Kinase Signaling, and Redox Regulation of Epigenetics.- Chapter 12 Redox regulation of stem cell function.- Chapter 13 Oxidative Stress in Infectious Diseases.- Chapter 14 Oxidative Stress in Aging.- Chapter 15 Oxidative Stress in Cancer.- Chapter 16 Redox Pathways as a Platform in Drug Development.

Fields of interestOxidative Stress; Medical Biochemistry; Cell Physiology



Due February 2013

2013. Approx. 400 p. 72 illus., 44 in color. Hardcover7 $209.00ISBN 978-94-007-5786-8

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J. H. Kleinschmidt, Institut für Biologie, Universität Kassel, Germany (Ed)

Lipid-Protein InteractionsMethods and Protocols

Contents Quartz Crystal Microbalances as Tools for Prob-ing Protein-Membrane Interactions.- Surface Plasmon Resonance for Measuring Interactions of Proteins with Lipid Membranes.- Probing the Thermodynamics of Protein-Lipid Interactions by Isothermal Titration Calorimetry.- Differential Scanning Calorimetry of Protein-Lipid Interac-tions.- Atomic Force Microscopy and Spectros-copy to Probe Single Membrane Proteins in Lipid Bilayers.- Optimized Negative-Staining Protocol for Lipid-Protein Interactions Investigated by Electron Microscopy.- Examining the Protein-Lip-id Complexes using Neutron Scattering.- Circular-Dichroism and Synchrotron-Radiation Circular-Dichroism Spectroscopy as Tools to Monitor Protein Structure in a Lipid Environment.- Struc-tural Characterization of Membrane Proteins and Peptides by FTIR and ATR-FTIR Spectroscopy.- Förster Resonance Energy Transfer as a Tool for Quantification of Protein-Lipid Selectivity.- A Guide to Tracking Single Transmembrane Proteins in Supported Lipid Bilayers.- Fluorescence Cor-relation Spectroscopy to Examine Protein Lipid Interactions in Membranes.- Analyzing Trans-membrane Protein and Hydrophobic Helix Topog-raphy by Dual Fluorescence Quenching.- Studying Lipid-Protein Interactions with Electron Paramag-netic Resonance Spectroscopy of Spin-Labeled Lipids.- EPR Techniques to Probe Insertion and Conformation of Spin-Labeled Proteins in Lipid Bilayers.- Solid-State NMR Approaches to Study Protein Structure and Protein-Lipid Interactions.- Solution NMR Spectroscopy for the Determina-tion of Structures of Membrane Proteins in a Lipid Environment. [...]

Fields of interestProtein Science; Lipidology



Due January 2013

2013. XIV, 524 p. 105 illus., 55 in color. (Methods in Molecular Biology, Volume 974) Hardcover7 $139.00ISBN 978-1-62703-274-2

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102

New SeriesCell Death in Biology and DiseasesSeries editors: X.-M. Yin, Z. Dong

Cell death, or conversely cell survival, is a major biological phenomenon. Just as cell proliferation and cell differentiation, cell death is a choice that a cell has to make, sometimes voluntarily, other times accidentally. As such, cell death serves a purpose in the biology of a multicellular organ-ism. The machinery for cell death and that which protects against cell death are evolutionarily conserved and their elements can even be found in single-celled organism. The disruption of the cell death mechanism can often cause developmental abnormalities. Factors that can trigger cell death are diverse and cell death can directly contribute to the pathogenesis of many diseases, including cancer, neurodegenerative diseases and tissue in-jury. The molecular mechanisms of cell death and cell survival are complicated and often intertwined with other cellular machineries, such as that for cell proliferation, cell differentiation, thus casting a broadly connected signaling network. The study of cell death and cell survival has become a multi-disciplinary subject, which requires expertise from all fields of the modern biology. The exploration of the role of cell death in disease development and the modulation of cell death for treating devastating disease demands constant update of our knowledge and broadest interactions among all investigators, basic and clinical. It is thus the aim of this book series to timely summarize the new development in cell death field and to present them in a systemic way so that they could be read-ily accessible by students, researchers, and clini-cians from different disciplinarians. We hope that this availability of a detailed set of information will turn into great opportunities for new discoveries and new applications in biology and in diseases.

D. E. Johnson, University of Pittsburgh, PA, USA (Ed)

Cell Death Signaling in Cancer Biology and TreatmentA key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art ap-proaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death.

Features 7 Describes state-of-the-art approaches and future opportunities for selective and efficient killing of tumor cells 7 Discusses preclinical and clinical approaches 7 Features development and application of novel agents and approaches

Contents Defective Apoptosis Signaling in Cancer.- The Warburg Effect and Beyond: Metabolic Dependen-cies for Cancer Cells.- Emerging Opportunities for Targeting the Tumor-Stroma Interactions for In-creasing the Efficacy of Chemotherapy.- The Role of Autophagy in Drug Resistance and Potential for Therapeutic Targeting.- microRNAs in Cell Death and Cancer.- Targeting DNA Repair Pathways for Cancer Therapy.- Molecular Chaperones and How Addiction Matters in Cancer Therapy.- Sphin-golipid Metabolism and Signaling as a Target for Cancer Treatment.- Leading Small Molecule In-hibitors of Anti-apoptotic Bcl-2 Family Members.- SMAC IAP Addiction in Cancer.- Harnessing Death Receptor Signaling for Cancer Treatment.- Proteasome Inhibition as a Novel Strategy for Cancer Treatment.- New Agents and Approaches for Targeting the RAS/RAF/MEK/ERK and PI3K/AKT/mTOR Cell Survival Pathways.- Activa-tion of Immune-Mediated Tumor Cell Death by Chemotherapy.

Fields of interestCell Biology; Apoptosis; Cancer Research



Due November 2012

2013. XV, 455 p. 40 illus., 31 in color. (Cell Death in Biology and Diseases, Volume 1) Hardcover7 $209.00ISBN 978-1-4614-5846-3

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T. Lübberstedt, Iowa State University, Ames, IA, USA; R. K. Varshney, ICRISAT, Patancheru, India (Eds)

Diagnostics in Plant BreedingContents Section 1. Introduction.- Chapter 1. Diagnostics in plants; T. Lübberstedt.- Chapter 2. Non-DNA biomarkers; Christin Falke.- Section 2. Identifica-tion of quantitative trait polymorphisms (QTPs).- Chapter 3. Gene identification: forward genetics; Qing Ji.- Chapter 4. Gene identification: reverse genetics; George Haughn.- Chapter 5. Allele re-sequencing technologies; Torben Asp.- Chapter 6. Association studies; Yongsheng Chen.- Section 3. Validation of QTPs.- Chapter 7. TILLING; Gunter Backes.- Chapter 8. Gene Replacement; Paul Hooykaas, Sylvia de Pater.- Section 4. Conver-sion of QTPs into Functional Markers.- Chapter 9. SNP genotyping technologies; Bruno Studer.- Chapter 10. INDEL genotyping technologies; Toshihiko Yamada et al.- Chapter 11. Sequenc-ing for genotyping; Rajeev Varshney.- Section 5. Development of Non-DNA Biomarkers.- Chapter 12. Methylation-based markers; Emidio Alber-tini, Gianpiero Marconi.- Chapter 13. RNA; Stefan Scholten.- Chapter 14. Metabolites; Olga Zabotina.- Section 6. Deposition of Diagnostic Marker information.- Chapter 15. Plant Genetic Databases; Carolyn Lawrence.- Section 7. Statisti-cal considerations.- Chapter 16. Epistasis, QTP x environment interactions, and pleiotropy: value of a FM; Everton Brenner.- Section 8. Applications in plant breeding.- Chapter 17. Parent selection – usefulness; Adel Abdel-Ghani.- Chapter 18. Variety registration and protection; David Lee et al.- Section 9. Examples.- Chapter 19. Maize; Min-gliang Xu et al.- Chapter 20. Rice; Yongzhong Xing et al.- Chapter 21. Traits; Birgit Arnholdt-Schmitt, Helia Cardoso.

Fields of interestPlant Breeding/Biotechnology; Plant Genetics & Genomics; Plant Sciences



Due February 2013


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103

E. Mohammadi Goltapeh, Tarbiat Modares University, Tehran, Iran; Y. Rezaee Danesh, Urmia University, Iran; A. Varma, Amity University Uttar Pradesh, Noida, India (Eds)

Fungi as BioremediatorsBiological remediation methods have been successfully used to treat polluted soils. While bacteria have produced good results in bioremedi-ation for quite some time now, the use of fungi to decontaminate soils has only recently been estab-lished. This volume of Soil Biology discusses the potentials of filamentous fungi in bioremediation. Fungi suitable for degradation, as well as geneti-cally modified organisms, their biochemistry, en-zymology, and practical applications are described. Chapters include topics such as pesticide removal, fungal wood decay processes, remediation of soils contaminated with heavy and radioactive metals, of paper and cardboard industrial wastes, and of petroleum pollutants.

Features 7 Contributions by leading international authori-ties in their fields 7 Chapters represent pioneer work and the most complete synthesis myco-remeditation 7 Provides new frontiers for future research

Contents Ecophysiology of Fungal Bioremediation.- Ap-plication of Mycoremediation Against Organic Pollutants.- Mycoremediation of Inorganic Pol-lutants.- Mycoremediation: Agricultural and Forest Ecosystem Sustainability.- Techniques in Mycoremediation.

Fields of interestEukaryotic Microbiology; Soil Science & Conser-vation; Environmental Engineering/Biotechnology



Due December 2012

2013. VIII, 540 p. 31 illus., 6 in color. (Soil Biology, Volume 32) Hardcover7 $189.00ISBN 978-3-642-33810-6

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N. G. Mueller, Washington University in Saint Louis, St. Louis, MO, USA

Mound Centers and Seed SecurityA Comparative Analysis of Botanical Assemblages from Middle Woodland Sites in the Lower Illinois Valley

At Middle Woodland sites in the eastern United States, excavations have uncovered naturalistic art worked on exotic materials from points as distant Wyoming, Ontario, and the Gulf Coast, revealing a network of ritual exchange referred to as the Hopewell phenomenon. Simultaneously, Middle Woodland societies developed the earliest agri-cultural system in eastern North American using now-extinct native cultivars. Mound Centers and Seed Security: A Comparative Analysis of Botani-cal Assemblages from Middle Woodland Sites in the Lower Illinois Valley integrates an interpreta-tion of these two historical trends.

Features 7 Includes a lengthy review of literature on both Hopewell studies and Middle Woodland agriculture 7 Synthesizes both original research and research reported in archaeological “grey literature" 7 Could be used as a teaching tool in upper level archaeology methods courses

Contents Introduction.- What is Hopewell?: The Lower Illinois Valley in a Regional Context.- Middle Woodland Subsistence and Settlement in the Lower Illinois Valley.- Plant Use at Mound House.- Comparative Analysis.- Conclusions: Mounds and Seed Exchange.

Fields of interestPlant Sciences; Plant Systematics/Taxonomy/ Biogeography; Plant Ecology



Due November 2012

2013. X, 80 p. 26 illus., 2 in color. (SpringerBriefs in Plant Science) Softcover7 $49.95ISBN 978-1-4614-5920-0

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W. Nentwig, University of Bern, Switzerland (Ed)

Spider EcophysiologyWith over 43,000 species, spiders are the largest predacious arthropod group. They have developed key characteristics such as multi-purpose silk types, venoms consisting of hundreds of compo-nents, locomotion driven by muscles and hydrau-lic pressure, a highly evolved key-lock mechanism between the complex genital structures, and many more unique features. After 300 million years of evolutionary refinement, spiders are present in all land habitats and represent one of the most successful groups of terrestrial organisms. Eco-physiology combines functional and evolutionary aspects of morphology, physiology, biochemistry and molecular biology with ecology. Cutting-edge science in spiders focuses on the circulatory and respiratory system, locomotion and dispersal abilities, the immune system, endosymbionts and pathogens, chemical communication, gland secre-tions, venom components, silk structure, structure and perception of colours as well as nutritional re-quirements. Spiders are valuable indicator species in agroecosystems and for conservation biology.

Features 7 Comprehensive reviews of all relevant recent research results 7 With contributions by renowned spider experts 7 Presents basic biological data and potential industrial applica-tions 7 With numerous excellent illustrations

Contents Respiration and Circulatory System.- Locomotion and Dispersal.- Immune system and pathogens.- Chemical Communication and Reproduction.- Venom.- Silk.- Colouration.- Nutrition.- Ecotoxi-cology.- Applications.

Fields of interestAnimal Physiology; Invertebrates; Animal Bio-chemistry



Due January 2013

2013. X, 590 p. 147 illus., 61 in color. Hardcover7 $209.00ISBN 978-3-642-33988-2

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104

S. E. Nicholson, N. A. Nicola, Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia (Eds)

JAK-STAT SignallingMethods and Protocols

Contents Analysis of Janus Tyrosine Kinase Phosphoryla-tion and Activation.- Co-Immunoprecipitation Protocol to Investigate Cytokine Receptor Associated Proteins e.g. Janus Kinases or Other Associated Signaling Proteins.- In Vitro JAK Kinase Activity and Inhibition Assays.- Quantita-tive Analysis of JAK Binding using Isothermal Titraion Calorimetry and Surface Plasmon Reso-nance.- Determination of Protein Turnover Rates in the JAK/STAT Pathway using a Radioactive Pulse-Chase Approach.- Designing RNAi Screens to Identify JAK/STAT Pathway Components.- The Use of JAK-Specific Inhibitors as Chemical Biology Tools.- Methods for Detecting Muta-tions in the Human JAK2 Gene.- Detection of Activated STAT Proteins.- Detection of Activated STAT Species Using Electrophoretic Mobility Shift Assay (EMSA) and Potential Pitfalls Arising from the Use of Detergents.- Flow Cytometric Analysis of STAT Phosphorylation.- Acetylation of Endogenous STAT Proteins.- Detection and Cellular Localization of Phospho-STAT2 in the Central Nervous System by Immunohistochemical Staining.- Nuclear Trafficking of STAT Proteins Visualized by Live Cell Imaging.- Characteriza-tion of STAT Self-Association by Analytical Ultracentrifugation.- Constitutively Active STAT5 Constructs.- Analysis of Suppressor of Cytokine Signalling (SOCS) Gene Expression by Real-Time Quantitative PCR.- Detection of Endogenous SOCS1 and SOCS3 Proteins by Immunoprecipita-tion and Western Blot Analysis.- In vitro Ubiquiti-nation of Cytokine Signaling Components. [...]

Fields of interestCell Biology; Cytokines and Growth Factors



Due November 2012

2013. XII, 328 p. 52 illus., 9 in color. (Methods in Molecular Biology, Volume 967) Hardcover7 $139.00ISBN 978-1-62703-241-4

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D. H. O’Day, A. Catalano, University of Toronto at Mississauga, ON, Canada (Eds)

Proteins of the NucleolusRegulation, Translocation, & Biomedical Functions

Features 7 A comprehensive overview of the diversity of nucleolar function 7 Data presented comes from a wide spectrum of species 7 Leading edge studies presented shed new light on nucleolar processes 7 Biomedical aspects of nucleolar function are detailed

Contents Part I Introduction.- Ch 1 Proteins of the nucleo-lus.- Part II The nucleolus and nucleolar proteins.- Ch 2 Functional consequences of nuclear and nucleolar architecture.- Ch 3 rDNA and nucleolo-genesis in Drosophila.- Ch 4 The nucleolus of Dic-tyostelium and other lower eukaryotes.- Ch 5 Hu-man rDNA genes.- Ch 6 Chromatin organization and the mammalian nucleolus.- Ch 7 Chaperones and multitasking proteins in the nucleolus.- Ch 8 Nucleolar localization/retention signals.- Ch 9 Nucleolar transport of putative GTPase GNL1 and related proteins.- Ch 10 Nucleolar protein anchor-ing and translocation.- Ch 11 The nucleolus as a stress response organelle.- Ch 12 The nucleolar aspect of breast cancer.- Ch 13 Cysteine protein-ase inhibitors in the nucleus and nucleolus in activated macrophages.- Ch 14 Nucleolar proteins and cancer.- Ch 15 Nucleolar transplantation and human embryogenesis.- Part V Conclusions.- Ch 16 The nucleolus from its formation to the future.

Fields of interestEntomology; Life Sciences, general; Protein Sci-ence



Due January 2013


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P. s. Rand, Wild Salmon Center, Portland, OR, USA; B. A. Berejikian, NOAA, Northwest Fisheries Science Center, Manchester, WA, USA; T. N. Pearsons, Grant County Public Utility District, Ephrata, WA, USA; D. L. Noakes, Oregon State University, Corvallis, OR, USA (Eds)

Ecological Interactions between Wild and Hatchery SalmonidsContents 1.Ecological interactions between wild and hatchery salmonids: an introduction to the special issue.-2. Mechanisms influencing competition between hatchery and wild juvenile anadromous Pacific salmonids in fresh water and their relative competitive abilities.- 3.Predation by hatchery yearling salmonids on wild subyearling salmo-nids in the freshwater environment: A review of studies, two case histories, and implications for management,- 4.Development of natural growth regimes for hatchery-reared steelhead to reduce residualism, fitness loss, and negative ecological interactions.- 5.PCD Risk 1: A tool for assess-ing and reducing ecological risks of hatchery operations in freshwater.- 6. Risk management of non-target fish taxa in the Yakima River Water-shed associated with hatchery salmon supplemen-tation.- 7. Ecological risk assessment of multiple hatchery programs in the upper Columbia watershed using Delphi and modeling approach-es.- 8. Lack of trophic competition among wild and hatchery juvenile chum salmon during early marine residence in Taku Inlet, Southeast Alaska.- 9. Spatial and trophic overlap of marked and unmarked Columbia River Basin spring Chinook salmon during early marine residence with im-plications for competition between hatchery and naturally produced fish10. - Wild chinook salmon survive better than hatchery salmon in a period of poor production.

Field of interestFish & Wildlife Biology & Management



Due October 2012

2012. Approx. 360 p. (Developments in Environmental Biology of Fishes, Volume 29) Hardcover7 approx. $209.00ISBN 978-94-007-5692-2

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105

G. R. Rout, A. B. Das, Orissa University of Agriculture & Technology, Bhubaneswar, India (Eds)

Molecular Stress Physiology of PlantsContents 1.Title: Abiotic and biotic stress tolerance in plants.- 2.Title: Molecular Mechanism of stress-resistance of photosynthetic machinery.- 3.Title: Salinity induced genes and molecular basis of salt tolerance strategies in mangroves.- 4.Title: PSII fluorescence techniques for measurement of drought and high temperature stress signal in crop plants: protocols and applications.- 5.Title: Salt tolerance in cereals: Molecular mechanism and applications.- 6.Title: Salt stress: A biochemi-cal and physiological adaptation of some Indian halophytes of Sundarbans.- 7.Title: Molecular physiology of osmotic stress in plants.- 8.Title: The physiology of reproductive - stage abiotic stress tolerance in cereals.- 9.Title: Salicylic acid: role in plant physiology and stress tolerance.- 10.Title: Role of calcium-mediated CBl-CIPK network in plant mineral nutrition and abiotic stress.- 11.Ti-tle: Isothermal calorimetry and Raman spectros-copy to study response of plants to abiotic and biotic stress.- 12. Title: Mechanism of plant toler-ance in response to heavy metals.- 13.Title: Brassi-nosteroids - Biosynthesis and role in growth devel-opment and thermo tolerance responses.- 14.Title: Submergence stress tolerance in crop plants.- 15. Title: Stress tolerance in plants: a proteomics ap-proach.-16.Title: Marker-Assisted Breeding (MBA for stress resistance in crop plants.- 17.Title: DNA Methylation Associated Epigenetic Changes in Stress Tolerance of Plants.

Fields of interestPlant Physiology; Protein Science; Plant Pathology



Due January 2013

2013. VI, 472 p. 105 illus., 49 in color. Hardcover7 $209.00ISBN 978-81-322-0806-8

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N. Salmaso, Istituto Agrario di S. Michele all’Adige (IASMA), Trento, Italy; L. Naselli-Flores, University of Palermo, Italy; L. Cerasino, G. Flaim, M. Tolotti, IASMA, S. Michele all’Adige, Italy; J. Padisák, University of Pannonia, Veszprém, Hungary (Eds)

Phytoplankton responses to human impacts at different scales16th Workshop of the International Association of Phytoplankton Taxonomy and Ecology (IAP)

Contents 1. Foreword.- 2. Phytoplankton response to a changing climate.- 3. Long-term trends and ?ne year-to-year tuning of phytoplankton in large lakes are ruled by eutrophication and atmospheric modes of variability.- 4. Deep living Planktothrix rubescens modulated by environmental con-straints and climate forcing.- 5. Resource ratio and human impact.- 6. Temperature modulated effects of nutrients on phytoplankton changes in a mountain lake.- 7. Coupling high-resolution measurements to a three-dimensional lake model to assess the spatial and temporal dynamics of the cyanobacterium Planktothrix rubescens in a medium-sized lake.- 8. Mixotrophic phytoplank-ton is enhanced by UV radiation in a low altitude, P-limited Mediterranean lake.- 9. Sedimentation of phytoplankton.- 10. Watershed land use types as drivers of freshwater phytoplankton structure.- 11. Catchement land use and trophic state impacts on phytoplankton composition.- 12. Phytoplankton dynamics in permanent and temporary Mediter-ranean waters.- 13. Present-absent.- 14. Bloom forming cyanobacterial complexes co-occurring in a subtropical large reservoir: validation of domi-nant eco-strategies. [...]

Fields of interestEcology; Biodiversity; Freshwater & Marine Ecol-ogy



Due December 2012

2012. Approx. 375 p. (Developments in Hydrobiology, Volume 221) Hardcover7 $209.00ISBN 978-94-007-5789-9

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K. Turksen, Ottawa Hospital Research Institute, ON, Canada (Ed)

Stem Cells and AgingMethods and Protocols

Features 7 Includes cutting-edge methods and proto-cols in the MiMB standard format 7 Provides step-by-step detail essential for reproducible results 7 Contains key notes and implementa-tion advice from the experts

Contents Comprehensive Hematopoietic Stem Cell Isolation Methods.- Serial Transplantation of Bone Marrow to Test Self-Renewal Capacity of Hematopoietic Stem Cells In Vivo.- Mouse Hematopoietic Stem Cell Transplantation.- Isolation, Characterization, and Transplantation of Adult Liver Progenitor Cells.- Isolation of Muscle-Derived Stem/Progeni-tor Cells Based on Adhesion Characteristics to Collagen-Coated Surfaces.- Human Myoblasts from Skeletal Muscle Biopsies: In Vitro Culture Preparations for Morphological and Cytochemi-cal Analyses at Light and Electron Microscopy.- Cardiac Stem Cell Senescence.- Isolation of Mesenchymal Stem Cells from Human Bone and Long-Term Cultivation Under Physiologic Oxygen Conditions.- Methods for Assessing Effects of Wnt/β-Catenin Signaling in Senescence of Mes-enchymal Stem Cells.- Intra-Femoral Injection of Human Mesenchymal Stem Cells.- Tracking of Replicative Senescence in Mesenchymal Stem Cells by Colony-Forming Unit Frequency.- Chromatin Immunoprecipitation Coupled by Quantitative Real-Time PCR as a Tool for Analyz-ing Epigenetic Regulation of Stem Cell Aging.- Quantitative Fluorescence In Situ Hybridization (Q-FISH) on Paraffine Embedded Tissue.

Fields of interestCell Biology; Stem Cells;



Due March 2013


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106

A. Varma, Amity University Uttar Pradesh, Noida, India; G. Kost, University of Marburg, Germany; R. Oelmüller, University of Jena, Germany (Eds)

Piriformospora indicaSebacinales and Their Biotechnological Applications

Sebacinales have emerged as a fascinating order with mutualistic plant-fungal symbionts that con-sists of exclusively beneficial fungi. This volume of Soil Biology presents an overview of the current results in Sebacinales research with a focus on the potential of these fungi in crop improvement and stress tolerance. The authors demonstrate that Sebacinales are not only extremely versatile in their associations with roots, but are also almost universally present as symptomless endophytes. With this extraordinary diversity, Sebacinales with the key fungus Piriformospora indica might pos-sess remarkable significance in natural ecosystems. Their biotechnological applications are expected to improve the quality of crops while maintaining ecologically and economically sustainable produc-tion systems.

Features 7 Chapters are written by leading experts in their respective field of knowledge and exper-tise 7 Provides practical laboratory proto-cols 7 The key fungus Piriformospora indica has been discovered by one of the authors/ editors

Contents Piriformospora indica as Beneficial Root Symbi-ont.- Interaction with Different Plant Species.- Re-sistance Against Biotic and Abiotic Stress Factors.- Piriformospora indica and Macronutrients for Plants.- Experimental Protocols for Piriformos-pora indica Studies.

Fields of interestMicrobiology; Agriculture; Plant Breeding/Bio-technology



Due December 2012

2013. X, 423 p. 107 illus., 64 in color. (Soil Biology, Volume 33) Hardcover7 $209.00ISBN 978-3-642-33801-4

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N. Volpi, F. Maccari, University of Modena & Reggio Emilia, Italy (Eds)

Capillary Electrophoresis of BiomoleculesMethods and Protocols

Contents Recent Advances in Capillary Electrophoresis-Based Proteomic Techniques for Biomarker Discovery.- Capillary Electrophoresis-mass Spectrometry of Carbohydrates.- Approaches to Enhancing the Sensitivyty of Carbohydrate Separations in Capillary Electrophoresis.- Deter-mination of Monosaccharides Derivatized with 2-Aminobenzoic Acid by Capillary Electropho-resis.- Determination of Mono- Di- and Oligo-saccharides by Capillary Electrophoresis with Capacitively Coupled Contactless Conductivity Detection.- Separation of Chitooligosaccharides in Acidic Solution by Capillary Electrophore-sis.- Capillary Electrophoresis for the Analysis of Glycosaminoglycan-derived Disaccharides.- High Throughput Capillary Electrophoresis Mass Spectrometry: From Analysis of Amino Acids to Analysis of Protein Complexes.- Separation of Amino Acids by Capillary Electrophoresis with Light-emitting Diode-induced Fluorescence in the Presence of Electroosmotic Flow.- Quantification of Arginine and Dimethylated Arginines in Hu-man Plasma by Field-amplified Sample Injection Capillary Electrophoresis UV Detection.- Cap-illary Electrophoresis-Mass Spectrometry for Peptide Analysis: Target-Based Approaches and Proteomics/Peptidomics Strategies.- High Resolu-tion Proteome/peptidome Analysis of Body Fluids by Capillary Electrophoresis Coupled with MS.- Contribution of CE to the Analysis of Protein or Peptide Biomarkers. [...]

Fields of interestBiochemistry, general; Electrophoresis



Due January 2013


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A. Zambonelli, University of Bologna, Italy; G. M. Bonito, Duke University, Durham, NC, USA (Eds)

Edible Ectomycorrhizal MushroomsCurrent Knowledge and Future Prospects

Edible ectomycorrhizal mushrooms (EEMMs) comprise more than 1000 species and are an im-portant food and forest resource. In this volume of Soil Biology, internationally recognized scientists offer their most recent research findings on these beguiling fungi. Topics covered include: complex ecological interactions between plants, EEMMs, and soil organisms; comparative genomics, high-throughput sequencing and modern research tools; genetic selection of fungal strains and techniques for inoculating plants; economic and social considerations surrounding wild collected EEMMs; and practical information concerning soil management and EEMM cultivation.

Features 7 Gives a modern approach to biology, culti-vation and ecology of fungi 7 With a focus on the economic and medicinal potential of fungi 7 With contributions by an international board of experts

Contents Biology & Ecology of Edible Ectomycorrhizal Mushrooms.- Cultivation of Edible Etomycorrhi-zal Mushrooms (with main focus on truffles) and case studies.- Wild Collected Edible Etomycorrhi-zal Mushrooms: Economics, Conservation, Man-agement.- The Edible Ectomycorrhizal Mushroom industry in the age of “-omics”.

Fields of interestAgriculture; Fungus Genetics; Food Science



Due December 2012

2013. VIII, 446 p. 28 illus., 19 in color. (Soil Biology, Volume 34) Hardcover7 $209.00ISBN 978-3-642-33822-9

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