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    GENITOURINARY SYSTEM

    Function:Promote excretion of nitrogenous waste productsMaintain F&E & acid base balance

    1. Kidneys

    - pair of bean shaped organ- Retro peritonially (back of peritoneum) on either side of vertebral column. Encasedin Bowmanss capsule.

    Parts:

    Renal pelvis pyenophritis inflamedCortexMedulla

    Nephrones basic living unit

    Glomerulus filters blood going to kidneys

    Function of kidneys:1.) Urine formation 25% of total CO (Cardiac Output) is received by kidneys

    1. Filtration Normal GFR/ min is 125 ml of blood

    2. Tubular Reabsorption 124ml ofultra infiltrates (H2O & electrolytes is for reabsorption)3. Tubular Secretion

    1 ml is excreted in urine

    2.) Regulation of BP:Predisposing factor:Ex: CS hypovolemia decrease BP going to kidneys

    Activation of RAAS

    Release of Renin (hydrolytic enzyme) at juxtaglomerular apparatus

    Angiotensin I mild vasoconstrictor

    Angiotensin II vasoconstrictor

    Adrenal cortex increase CO increase PR

    Aldosterone Increase BP

    Increase Na &H2O reabsorption

    Hypervolemia

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    2.Ureters 25 35 cm long, passageway of urine to bladder

    3.Bladder Muscular & elastic tissue that is distensible located behind symphisis pubis.

    Function reservoir or urine

    1200 1800 ml Normal adult can hold200 500 ml needed to initiate micturition reflex

    Color amberOdor aromaticConsistency clear or slightly turbidpH 4.5 8Specific gravity 1.015 1.030

    WBC/ RBC (-)Albumin (-)E coli (-)Mucus thread fewAmorphous urate (-)

    4.Urethra extends to external surface of body. Passage of urine, seminal & vaginal fluids.

    - Women 3 5 cm or 1 to 1 - Male 20cm or 8

    URINARY TRACT INFECTION1. CYSTITIS

    inflammation of bladder

    Predisposing factors:1. Microbial invasion E. coli2. High risk women3. Obstruction4. Urinary retention5. Increase estrogen levels

    6. Sexual intercourse

    Signs & Symptoms:1. Pain flank area2. Urinary frequency & urgency3. Burning upon urination4. Dysuria & hematuria5. Fever, chills, anorexia, gen body malaise

    Diagnostic Exam:1. Urine culture & sensitivity - (+) to E. coli

    Nursing Management:1. Force fluid 2000 ml2. Warm sitz bath to promote comfort

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    3. Monitor & assess for gross hematuria4. Acid ash diet cranberry, vit C -OJ to acidify urine & prevent bacterial

    multiplication5. Meds: systemic antibiotics

    AmpicillinCephalosporinSulfonamides cotrimaxazole (Bactrim)- Gantrism (ganthanol)Urinary antiseptics Mitropurantoin (Macrodantin)Urinary analgesic- Pyridum

    Health Teachings:a.) Importance of Hydrationb.) Void after sexc.) Female avoids cleaning back & front

    Bubble bath, Tissue paper, Powder, perfumed.) Complications:

    Pyelonephritis

    2. PYELONEPHRITIS acute/ chronic inflamation of 1 or 2 renal pelvis of kidneys leading to tubulardestruction, interstitial abscess formation. Lead to Renal Failure

    Predisposing factors:1. Microbial invasion

    a.)E. Coli

    b.)Streptococcus2. Urinary retention /obstruction3. Pregnancy4. DM5. Exposure to renal toxins

    Signs & Symptoms:1.) Acute pyelonephritis

    a.) Costovertibral angle pain, tendernessb.)Fever, anorexia, gen body malaise

    c.) Urinary frequency, urgencyd.)Nocturia, dsyuria, hematuriae.)Burning on urination

    2.) Chronic Pyelonephritisa.)Fatigue, wt lossb.)Polyuuria, polydypsiac.) HPN

    Diagnostic Exam:1. Urine culture & sensitivity (+) E. coli & streptococcus

    2. UrinalysisIncrease WBC, CHON & pus cells

    3. Cystoscopic exam urinary obstruction

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    Nursing Management:1. Provide CBR acute phase2. Force fluid3. Acid ash diet4. Meds:

    a.) Urinary antiseptic nitrofurantoin (macrodantin)SE: peripheral neuropathyGI irritationHemolytic anemiaStaining of teeth

    b.)Urinary analgesic Peridium

    Complication- Renal Failure

    NEPHROLITHIASIS / UROLITHIASIS- formation of stones at urinary tract- calcium oxalate uric acid

    milk cabbage anchoviescranberries organ meatnuts tea nutschocolates sardines

    Predisposing factors:1. Diet increase Ca & oxalate2. Hereditary gout3. Obesity4. Sedentary lifestyle5. Hyperparathyroidism

    Signs & Symptoms:1. Renal colic2. Cool moist skin (shock)3. Burning upon urination4. Hematuria5. Anorexia, n/v

    Diagnostic Exam:1. IVP intravenous pyelography. Reveals location of stone2. KUB reveals location of stone3. Cytoscopic exam- urinary obstruction4. Stone analysis composition & type of stone5. Urinalysis increase EBC, increase CHON

    Nursing Management:1. Force fluid2. Strain urine using gauze pad3. Warm sitz bath for comfort

    4. Alternate warm compress at flank area5. Medsa.) Narcotic analgesic- Morphine SO4

    b.) Allopurinol (Zyeoprim)

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    c.) Patent IV lined.) Diet if + Ca stones acid ash diet

    If + oxalate stone alkaline ash diet - (Ex milk/ milk products)If + uric acid stones decrease organ meat / anchovies sardines

    Surgery Treatment:Nephectomy

    removal of affected kidneyLitholapoxy removal of 1/3 of stones- Stones will recur. Not advised for

    pt with big stonesExtracorporeal shock wave lithotripsy

    - Non - invasive- Dissolve stones by shock wave

    Complications:Renal Failure

    BENIGN PROSTATIC HYPERTROPHY

    - enlarged prostate gland leading to:a.) Hydro ureters dilation of uretersb.)Hydronephrosis dilation of renal pelvisc.) Kidney stonesd.)Renal failure

    Predisposing factor:1. High risk 50 years old & above

    60 70 (3 to 4 x at risk)2. Influence of male hormone

    Signs & Symptoms:1.Decrease force of urinary stream2.Dysuria3.Hematuria4.Burning upon urination5.Terminal bubbling6.Backache7.Sciatica

    Diagnostic Exam:

    1. Digital rectal exam enlarged prostate gland2. KUB urinary obstruction3. Cystoscopic exam obstruction4. Urinalysis increase WBC, CHON

    Nursing Management:1. Prostatic message promotes evacuation of prostatic fluid2. Limit fluid intake3. Provide catheterization4. Meds:

    a. Terazozine (hytrin) - Relaxes bladder sphincter

    b. Fenasteride (Proscar) - Atrophy of Prostate Gland

    Surgery Treatment:*Prostatectomy TURP- Transurethral resection of Prostate- No incision

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    -Assist in cystoclysis or continuous bladder irrigation.

    Nursing Management:c. Monitor symptoms of infectiond. Monitor symptoms gross/ flank bleeding. Normal bleeding within 24h.3. Maintain irrigation or tube patent to flush out clots - to prevent bladderspasm & distention

    ACUTE RENAL FAILURE sudden immobility of kidneys to excrete nitrogenous waste products & maintain

    F&E balance due to a decrease in GFR. (N 125 ml/min)

    Predisposing factors:1. Pre renal cause- decrease blood flowCauses:

    1. Septic shock2. Hypovolemia3. Hypotension decrease flow to kidneys4. CHF5. Hemorrhage6. Dehydration

    2. Intra-renal cause involves renal pathology= kidney problem1. Acute tubular necrosis-2. Pyelonephritis3. HPN4. Acute GN

    3. Post renal cause involves mechanical obstruction1. Stricture2. Urolithiasis3. BPH

    CHRONIC RENAL FAILURE irreversible loss of kidney function

    Predisposing factors:1. DM2. HPN3. Recurrent UTI/ nephritis4. Exposure to renal toxins

    Stages of CRF1. Diminished Reserve Volume asymptomatic

    Normal BUN & Crea, GFR < 10 30%2. Renal Insufficiency3. End Stage Renal disease

    Signs & Symptoms:

    1.) Urinary System 2.) Metabolic disturbances

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    a.) polyuriab.) nocturiac.) hematuriad.) Dysuriae.) oliguria

    a.) azotemia (increase BUN &Crea)b.) hyperglycemiac.) hyperinulinemia

    3.) CNS

    a.) headacheb.) lethargyc.) disorientationd.) restlessnesse.) memory impairment

    4.) GIT

    a.) n/vb.) stomatitisc.) uremic breathd.) diarrhea/ constipation

    5.) Respiratorya.) Kassmauls respb.) decrease cough reflex

    6.) Hematologicala.) Normocytic anemia

    bleeding tendencies

    7.) Fluid & Electrolytes

    a.) hyperkalemiab.) hypernatermiac.) hypermagnesemiad.) hyperposphatemiae.) hypocalcemiaf.) met acidosis

    8.) Integumentary

    a.) itchiness/ pruritusb.) uremic frost

    Nursing Management:1. Enforce CBR2. Monitor VS, I&O3. Meticulous skin care. Uremic frost assist in bathing pt

    4. Meds:a.) Na HCO3 due Hyperkalemiab.) Kagexelate enemac.) Anti HPN hydralazined.) Vit & mineralse.) Phosphate binder

    (Amphogel) Al OH gel - S/E constipationf.) Decrease Ca Ca gluconate

    5. Assist in hemodialysis1.)Consent/ explain procedure2.)Obtain baseline data & monitor VS, I&O, wt, blood exam3.)Strict aseptic technique4.)Monitor for signs of complications:

    B bleedingE embolismD disequilibrium syndromeS septicemiaS shock decrease in tissue perfusion

    Disequilibrium syndrome from rapid removal of urea & nitrogenous waste prodleading to:

    a.) n/vb.)HPN

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    c.) Leg crampsd.)Disorientatione.)Paresthesia

    2. Avoid BP taking, blood extraction, IV, at side of shunt or fistula. Can lead tocompression of fistula.

    3. Maintain patency of shunt by:i. Palpate for thrills & auscultate for bruits if (+) patent shunt!ii. Bedside- bulldog clip- If with accidental removal of fistula to prevent embolism.- Infersole (diastole) common dialisate used

    Complication- Peritonitis- Shock

    Surgery Treatment:

    *Renal transplantation Complication rejection. Reverse isolation