HACCP AS A LIFESPAN EXTENSION MANAGEMENT SYSTEM

“Empowering Self-Directed Health-span/Life-span Extension”

Presented by Morris Johnson

“CITIZEN-SCIENTIST”

CTO OF PHARMA INC.

Box 33, Road 707 S, Beaubier, Sk., Ca., S0C-0H0

Canterpene (at) gmail.com, 701-240-9411, 306-447-4944

HACCP?

Hazard Analysis Critical Control Points

Food and pharmaceutical safety

Adopted worldwide in 1980's

Comprehensive

Integrated

System

Key Element:

Critical Control Points (CCPs)

12 step life-cycle Manages 5 Key aspects

Preventative

Regenerative

Enhancement

Crisis management

Palliative

+Safety System supported by QA/QC Management

Six-Sigma

DMAIC error correction cycle

< 6 per 1 million

LEAN

Eliminate waste

Reduce variation

“Open source access” to published research is QA/QC tool

1-Assemble HACCP team

You are your own

HACCP Coordinator

(System Administrator)

2-Describe product and process

Your History:

Statistics

Health and Family

Personalization (profiling):

Genomic

Metabolomic

Microbiomic

Biomarker

3-Identify intended use

What life stage are you at ?

Infancy/Childhood

Youth/Adulthood,

Mid-life/Old-age

Your life plans ?

4-Schematic process flow Diagram

6 hazard analysis domains:

Nutrigenomics

Metabolomics

Microbiomics

Environomics

Epigenomics

Psychomics

5-On-site Verification

personalize everything

6-Complete a Hazard Analysis

Pre-requisites Analyses before plan is operational

Record cycle of events

HACCP is not paper bound

e-health data management technology

make this

an Operating System

7-CCP Determination:

Aubrey de Grey’s “7 deadly sins of biology” (SENS):

1-Junk inside cells,

2 Junk outside cells ,

3-Too few cells,

4-Too many cells,

5-Chromosome mutations ,

6-Mitochondrial mutations,

7-Protein cross-links,

I suggest 2 more:

8 Regulatory mutations & 9 microbiota (Metagenome)

8-Set Critical Limits for hazard reduction

Biological pathway limits are:

Science-driven

Modified by:

“Moral Hazards”

9-Patient-Centric Monitoring

Narrow AGI renders this function invisible

Integration of structure , form and function

(Data, Devices , software and infrastructure )

Consumer acceptance of intrusive and pervasive devices ?

e.g. clothes, jewelry and implants

Social , Privacy , Civil and Criminal law issues

10-Establish Deviations

Corrective/preventative measures (CPM)

Recall Plan

Core System Resources

My Inspiration for

“HACCP for Humans”

AKA “ARLA”

“Advanced Regenerative Lifespan Augmentation “ (Patent Pending)

11-Verification / Validation

Chosen procedure(s) operating

as originally designed or intended?

Hazard sufficiently controlled ?

Regulatory bodies functions?

Assistance from emerging AGI technologies.

12-Record /Document Management and Audits

System-wide open-source data

”Managing all risks at CCP’s

within the 5 domains of medicine

while designing / running simulations

and hot-patching bio-code

would make an AGI happier than a pig in shit”

RECALL PLAN

PALLIATION and a funeral VS:

CRYONICS and ENCHANCMENT

Upgradable humans - a new economic paradigm.

Re-work, a first step towards self-directed evolution

Making the market value of life and health

more valuable than death

Periodic Audit/Revision

User-defined:

Self or third party

Continuous improvement:

“just Me and my AGI enabled agent”

A challenge and a business opportunity:

“Commercializing an operating system

needs that token commercialization person”

Pre-requisite domains for Health Management

6 “Omics” pre-requisite domains.

Bullets added as system audits justify them.

Canada’s food safety HACCP system

Has 6 domains and 72 bullets

1-Nutrigenomics

All molecules small and large drive the ‘Omics.

No distinction between:

foods, supplements and pharmaceuticals..

They just have different temporal and activity coefficients

e.g. http://en.wikipedia.org/wiki/Marshall_Protocol

2-Metabolomics

Metabolic feedback loops:

Subclinical inflammation

“Metabolic syndrome”

Personalized metabolic loops:

Modeled

Generated

Predicatably managed

3-Microbiomics

Distributed biofilms :

metabolomic ,

epigenomic

nutrigenomic

Ethno-Endogenous

Exogenous

DIY

4-Environomics

Physical Stress Biological Stress Chemical Stress Social Stress

5-Epigenomics

USA Patent Number 6541680

Nutritional methyl supplements………

6-Psychomics- “Dog in the manger” “moral hazards”

The biological Moral Hazard:

The Placebo Effect

Non-biological Moral Hazards:

Political

Military

Economic Legal

Regulatory

Theistic

Social

Cultural

"The Longevity Dividend"

Measuring the value of life VS death

QALY cost of regeneration VS palliation:

Pension and insurance industries

“Third Bridge” technologies

You bet your life depends upon it

HACCP makes the “longevity dividend” :

Sustainable

Affordable

HACCP 4 “ARLA” TAKE-HOME POINTS

Extreme health-span and life-span extension requires:

A robust management system with history of use

Mainstream adoption for universal accessibility

Moral hazard control to save the boomers

Money to commercialize the science

AGI technology to grow the system

Open-sourcing to enable Citizen-Science

A SWOT analysis as a first step

“HACCP 4 ARLA” method And system

creates a Novel Comprehensive

Health Records and planning Data-set.

“Open sourced” compiled database

with Encrypted IDs, analyzed, mined

yields the capacity for Individuals to

self-direct their own Robust Personal

Lifespan/Healthspan Management program

in a Six-sigma and Lean manner.

Current systems do not empower you.>>>>

With HACCP “YOU” control everything “Product, Process, Premises, Personnel”.Become a Citizen-Scientist and Experience the “Longevity Dividend” with Me.

I’d like to thank Alex Lightman and H+

for Inviting me , as well as my Sponsors:

my Company Shareholders & Partners

http://hplusmagazine.com/articles/forever-young/hemp-victory-over-aging

What we are not

What we are:

Strong Science ,Trademarked and Patented

This Presentation has been Open Source Reviewed

Thank You…..Questions?