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HEALTHTECH HEARTBEAT Q2 2018 MARKET REVIEW

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Page 1: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

HEALTHTECH

HEARTBEAT

Q2 2018 MARKET REVIEW

Page 2: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

2

SECTOR-LED SPECIALISTS IN M&A AND FUNDRAISING

Years ofRI DEALS 3 Sectors

Deals inPast 2 Years

25+ 30+

50 People

15 Nationalities 3 Offices 1,000+ Buyers& Investors

100%Referenceable

Page 3: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

3

HEALTHTECH HIGHLIGHTS Q2 2018

Welcome to the Q2 2018 edition of the HealthTech Heartbeat – Results International’s quarterly market update of the HealthTech

segment covering both Biopharma and Healthcare IT.

Highlights in the quarter include:

• An 11.8% increase in the Results International HealthTech indices over the last three month, led by Biopharma IT and US

Healthcare IT, demonstrating the premium on innovative technology:

o Four US HealthTech stocks exceeded 40% increases in share price quarter-to-quarter, including Teladoc and Tabula Rasa

who have both experienced consistent share price growth since IPO and currently trade at 7.4x and 10.5x revenue

respectively

• High-profile Private Equity funds investing heavily and proving to be more than a match for their trade counterparts, most

notably Veritas Capital Fund Management acquired the Value-Based Care Division of GE Healthcare for $1.1bn in cash

• Medidata Solutions acquiring SHYFT Analytics, a US-based life science data analytics firm, for $195m, following their

commercial partnership in 2016. The acquisition strengthens Medidata’s ability to analyse clinical, real-world and commercial

data, and post market announcement Medidata secured a 6% uplift in its share price

• The HealthTech fundraising and IPO market remains active; UK-based Benevolent AI, achieved a further investment of $115m

to continue developing its core “AI brain”, in a move that strengthens the company’s opportunity to disrupt the pharma

industry and there are continued rumours of a return to the public market for Change Healthcare, which was taken private by

Blackstone in 2011 for $3bn

M&A activity in the sector remains healthy and fundraising appetite strong. As a result, now is a good time to be contemplating

fundraising, exit or growth through acquisition in the HealthTech space – if you are, please do get in touch.

Page 4: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

4

RI GLOBAL HEALTHTECH INDICES

70

80

90

100

110

120

130

140

Jun 17 Jul 17 Aug 17 Sep 17 Oct 17 Nov 17 Dec 17 Jan 18 Feb 18 Mar 18 Apr 18 May 18

Healthcare IT - Europe Healthcare IT - US Biopharma IT Generalists NASDAQ Comp FTSE 100

(1) Excludes GeneralistsNotes: Based on share prices as at 30th June 2018; indices weighted by market capitalisation; Healthcare IT – US excl. McKesson because the majority of its rev. is generated from pharmaceutical distributionSources: Capital IQ and Results analysis

LAST

12

MO

NTH

SH

AR

E P

RIC

E P

ER

FO

RM

AN

CE (

%)

Q2 2018 PERFORMANCE

Biopharma IT 13.5%

Generalists 3.1%

Healthcare IT - US 13.1%

Healthcare IT - Europe (2.6%)

HealthTech(1) 11.8%

(0.2%)

2.5%

(0.4%)

22.3%

17.7%

4.4%

Jul-17 Aug-17 Sep-17 Oct-17 Nov-17 Dec-17 Jun-18Apr-18 May-18Jan-18 Feb-18 Mar-18

Page 5: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

5

HEALTHTECH: SHARE PRICE PERFORMANCE

(10.8%)

10.5%

(3.4%)

65.3%

(18.9%) (10.0%) (6.0%)

13.2% 13.3%

(24.5%)

0.3%

(17.0%)

3.8%

(21.7%)

67.3%

2.4%

324.1%

25.4%3.0%

49.6%

(50.0%)

0.0%

50.0%

100.0%

150.0%

200.0%

250.0%

300.0%

350.0%

0.3%

(10.4%)

9.6%

20.3%

(5.3%)

3.1%

(2.8%)

11.3%

42.9%

(6.4%)

12.7%

47.7%

10.0% 8.5%

44.0%

16.4%

64.5%

5.3%

28.3%

19.5%

(20.0%)

(10.0%)

0.0%

10.0%

20.0%

30.0%

40.0%

50.0%

60.0%

70.0%

Note: Based on share prices as at 30th June 2018Sources: Capital IQ and Results analysis

LAST

12

MO

NTH

SQ

2 2

01

8

HEALTHCARE IT - EUROPE HEALTHCARE IT - US BIOPHARMA IT

Page 6: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

6

HEALTHTECH: SELECTED STOCKS – PERFORMANCE SINCE IPO

Note: Calendarised to December year end; $ millions, except share price data; multiples capped at 20x EV / Revenue and 50x EV / EBITDASource: Capital IQ

COMPANYIPO

DATEDESCRIPTION

RAISED

($M)INDICATIVE

PRICE RANGE ($)

IPO LISTING

PRICE ($)

INCREASE

VS. RANGE

DAY 1

INCREASE

CURRENT

INCREASE(1)

EV ($M)EV /

REVENUE

EV /

EBITDA

IPO CURRENT IPO CURRENT IPO CURRENT

Nasdaq

Sep-16Medication regimen

optimisation software52 13.00-15.00 12.00 (14.3%) 24.0% 431.9% 237 1,432 2.7x 7.4x 19.7x 48.3x

Nasdaq

Jun-16

Data analytics platform and

diagnostics for precision

medicine

91 12.50-15.50 14.00 0.0% 32.8% (76.4%) 1,732 510 11.4x 5.2x n.m. n.m.(2)

NYSE

Jun-15Video telehealth platform for

medical consultations157 15.00-17.00 19.00 18.8% 50% 205.5% 693 4,127 9.7x 10.5x n.m. n.m.(3)

NYSE

Jun-15Healthcare delivery and

payments software 196 14.00-16.00 17.00 13.3% 10.9% 23.8% 486 1,681 3.1x 2.9x n.m. n.m.(4)

Nasdaq

Feb-15Cloud-based healthcare data

analytics software600 24.00-26.00 27.00 8.0% 0.0% (63.2%) 3,474 1,316 8.0x 2.3x 23.4x 8.2x

NYSE

Mar-14Healthcare enterprise

management software 178 13.00-15.00 16.00 14.3% 148.8% (73.4%) 1,333 553 n.m. 3.6x n.m. n.m.(5)

NYSE

Oct-13Cloud-based CRM software

for the biopharma industry 261 16.00-18.00 20.00 17.6% 85.8% 284.3% 2,218 11,338 11.3x 13.9x n.m 42.3x

(1) Current increase from IPO price; market data as of 30th June 2018(2) NantHealth projecting negative EBITDA for CY2018; was not profitable in year of IPO(3) Teladoc multiples capped at 50x EV / EBITDA; was not profitable in year of IPO(4) Evolent Health multiples capped at 50x EV / EBITDA; was not profitable in year of IPO(5) Castlight projecting negative EBITDA for CY2018; was not profitable in year of IPO

Page 7: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

7

HEALTHTECH: PUBLIC COMPANY VALUATION BENCHMARKS

REVENUE GROWTH (2018-19E) EV / REVENUE 2018E

EBITDA MARGIN 2018E EV / EBITDA 2018E

6.2%

4.2%

11.9%

17.8%

10.1%

0.0%

2.0%

4.0%

6.0%

8.0%

10.0%

12.0%

14.0%

16.0%

18.0%

20.0%

Generalists Healthcare IT

- Europe

Healthcare IT

- US

Biopharma IT HealthTech

33.3%

27.2%

16.2%

24.2%

18.0%

0.0%

5.0%

10.0%

15.0%

20.0%

25.0%

30.0%

35.0%

Generalists Healthcare IT

- Europe

Healthcare IT

- US

Biopharma IT HealthTech

4.9 x

3.4 x 3.3 x

7.4 x

3.5 x

0.0 x

1.0 x

2.0 x

3.0 x

4.0 x

5.0 x

6.0 x

7.0 x

8.0 x

Generalists Healthcare IT

- Europe

Healthcare IT

- US

Biopharma IT HealthTech

17.0 x

12.6 x14.4 x

30.4 x

13.9 x

0.0 x

5.0 x

10.0 x

15.0 x

20.0 x

25.0 x

30.0 x

35.0 x

Generalists Healthcare IT

- Europe

Healthcare IT

- US

Biopharma IT HealthTech

Notes: EV = Enterprise Value; financials calendarised to December year end; median values reported; McKesson excl. from above analysis because majority of rev. is generated from pharmaceutical distribution See Selected Publicly Traded Companies (slide 12) for details of companies included in each category; HealthTech excludes GeneralistsSource: Capital IQ

Page 8: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

8

HEALTHTECH: PUBLIC COMPANY VALUATION PERFORMANCE

OVER TIME

3.5 x

2.0x

2.5x

3.0x

3.5x

4.0x

4.5x

EV / CY Revenue

Median

13.9 x

10.0x

11.0x

12.0x

13.0x

14.0x

15.0x

16.0x

17.0x

EV / CY EBITDA

Median

LTM Q2 2018

% CHANGE

Median (5.3%) (2.1%)

LTM Q2 2018

% CHANGE

Median (4.3%) (0.0%)

Notes: EV = Enterprise Value; financials calendarised to December year end, which can impact the multiples at the start of each year as the base is shifted forward; weekly tracking of valuation multiples commenced in July 2015, October 2014 – June 2015 tracked on a quarterly basis, therefore a linear progression has been assumed between quarters up to July 2015Source: Capital IQ

15

19(1)

(1)

(1) Number of companies with applicable multiples in Q2 2018 index

Q4-14 Q1-15 Q2-15 Q3-15 Q4-15 Q1-16 Q2-16 Q3-16 Q4-16 Q1-17 Q2-17 Q3-17 Q4-17 Q1-18 Q2-18

Q4-14 Q1-15 Q2-15 Q3-15 Q4-15 Q1-16 Q2-16 Q3-16 Q4-16 Q1-17 Q2-17 Q3-17 Q4-17 Q1-18 Q2-18

Page 9: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

9

HEALTHTECH: GLOBAL M&A ACTIVITY Q1 2012 – Q2 2018

Sources: Press releases, Capital IQ, Mergermarket, 451 Research and Results analysis

NU

MB

ER

OF D

EA

LSTO

TAL D

ISC

LSO

ED

DEA

L VA

LUE ($

M)

21

17

20

32

29

18

28 27 28

32

44

61

54

49

70

56 56

63 62

39

43

5654

48

57

47

4

3

5

1

1

7

2

7 5

6

2

8

12

5

5

2

11

8

6

7

8

11

9

7

7

7

0

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

18,000

0

10

20

30

40

50

60

70

80

Q1

2012

Q2

2012

Q3

2012

Q4

2012

Q1

2013

Q2

2013

Q3

2013

Q4

2013

Q1

2014

Q2

2014

Q3

2014

Q4

2014

Q1

2015

Q2

2015

Q3

2015

Q4

2015

Q1

2016

Q2

2016

Q3

2016

Q4

2016

Q1

2017

Q2

2017

Q3

2017

Q4

2017

Q1

2018

Q2

2018

Healthcare IT Biopharma IT Healthcare IT Total Disclosed Deal Value Biopharma IT Total Disclosed Deal Value

Page 10: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

10

HEALTHTECH: SELECTED DEALS IN Q2 2018

DATE BUYER TARGET EV ($M)EV/ (1)

REVENUEEV/EBITDA COMPANY DESCRIPTION

TARGET

LOCATION

Jun-18 352.0 5.6x n.m. Virtual care provision

Jun-18 - - - Healthcare analytics and population health management solutions

Jun-18 195.0 7.8x(2) - Data management and analytics

Jun-18 - - - Pharmaceutical risk analysis

Jun-18 - - - Compliance and quality assurance

Jun-18 - - - Obstetric and gynecological data management

May-18 - - - Patient management and workforce optimisation

May-18 - - - Electronic patient record and hospital administration

May-18 - - - Data analysis acceleration solutions

May-18 - - - Patient care management

May-18(Assets)

13.0 - - Healthcare insurance claim management

May-18 60.0 - - Personalised patient engagement solution

Apr-18 - - - Data analysis and cleaning

Apr-18 - - - Patient safety

Apr-18 - - -Workforce optimisation software for the healthcare defense and maritime

industries

Apr-18 9.7 2.9x 20.3x(3)

Cloud-based medical record system

Apr-18 9.0 1.9x 8.7x Healthcare document and process management

Apr-18(Value-Based Care Division)

1,050.0 - - Revenue-cycle, ambulatory care and workforce management

(1) In certain cases EV/Revenue are publicly reported estimates; TTM financials have been used where possible; EV = transaction value scaled to 100% shareholding plus net debt (incl. minority interest)

(2) Calculated off projected revenue run rate of $25m for CY18(3) Multiple calculated based on EBITSources: Press releases, Capital IQ, Mergermarket, 451 Research and Results analysis

Page 11: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

11

HEALTHTECH: SELECTED FUNDRAISINGS IN Q2 2018DATE COMPANY TYPE OF ROUND

FUNDSRAISED ($M)

INVESTOR PARTICIPATION COMPANY DESCRIPTIONCOMPANYLOCATION

Jun-18 Venture 3.2 Albion Capital Group Data capture and patient engagement

Jun-18 - 36.0 Kinnevik; Founders Fund; Thrive Capital; Lakestar Advisors; Sound Ventures Patient financial management

Jun-18 Series B 62.5 Accel Partners; Creandum; Index Ventures; Project A VenturesOnline medical advice and care services provision platform

Jun-18 Growth 60.0 Mainsail Partners Compliance and patient security

Jun-18 Series C 30.0Johnson & Johnson Innovation; NVIDIA Corporation; Aurum Ventures MKI; Intermountain Healthcare; Khosla Ventures; OurCrowd; Dolby Family Ventures; aMoon Partners

AI radiology analytics

May-18 Series D 60.0Vulcan Capital; Volition Capital; Goldman Sachs; First Mark; F-Prime Capital Partners

Pharmaceutical supply chain compliance

May-18 Series B 21.0 Polaris Partners; General Catalyst Partners; 7wire Ventures Healthcare data analytics

May-18 Series A 13.4Neptune Investment Management; Tanarra Capital Australia; GT Healthcare Capital Partners; Oxford Sciences Innovation; Rohit Thakur Consulting

Coronary heart disease diagnosis

May-18 - 500.0 AIA Company; NWS Holdings; China Capital Zhongcai Fund Management Hospital appointment registration

May-18 . Series C 55.0Temasek Holdings; Baillie Gifford & Co.; Amgen Ventures; Merck Ventures; Canepa Healthcare; Jazz Venture Partners; Brooklands Capital Strategies

Interactive medical information platform

May-18 Series B 16.8 Benchmark; Aspect Ventures; Greylock Partners Doctor appointment booking system

May-18 Growth 37.6 JMI Equity Patient engagement software

Apr-18 - 115.0 Woodford Investment Management AI biomedical information analytics

Apr-18 Series C 74.0

VR Adviser; Qualcomm Ventures; Goldman Sachs Asset Management; Shasta Ventures; Tenaya Capital; Lerer Hippeau Ventures; Sherpa Ventures; Wil; Blue Cloud Ventures; Princeville Global; Ridgeview Asset Management Partners

Online medical consultation software platform

Apr-18 Series B 36.4 New Enterprise Associates; Flare Capital Management Company; Amgen Ventures; Lakestar Advisors; Oxeon Ventures

Biopharma data analytics

Apr-18 Series E 105.0

Draper Fisher Jurvetson; Kleiner Perkins Caufield & Byers; Sapphire Ventures; General Catalyst Partners; Kinnevik; Merck Global Health Innovation Fund; 7wire Ventures; M12; Zaffre Investment; Echo Health Ventures

Diabetes management solution

Apr-18 Series B 33.5 Canaan Partners; Draper Fisher Jurvetson; Casdin Capital; GE Ventures; Section 32; LifeForce Capital

Cell and gene therapy chain management software

Apr-18 Venture 9.9Boehringer Ingelheim, Investment Arm; Oxford University Innovation; Parkwalk Advisors Ltd; Chimera Partners

Neurological and cerebrovascular imaging platform

Sources: Press releases, Capital IQ and Results analysis

Page 12: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

12

HEALTHTECH: SELECTED PUBLICLY TRADED COMPANIESOPERATING METRICS VALUATION METRICS

PRICE % OF 52 MARKET TOTAL NET ENTERPRISE REVENUE REV. GROWTH GROSS MARGIN REVENUE EBITDA

COMPANY (30-JUN-18) WEEK HIGH CAP CASH DEBT VALUE CY2018 CY18-19 HISTORICAL CY2018 CY2019 CY2018 CY2019 CY2018 CY2019

GENERALISTS WITH SIGNIFICANT HEALTHTECH EXPOSURE

HEALTHCARE IT - EUROPE

EBITDA MARGIN

HEALTHCARE IT - US

BIOPHARMA IT

(1) McKesson excluded from ‘Healthcare IT – US’ summary analysis above because majority of revenue is generated from pharmaceutical distributionNote: Calendarised to December year end; $ millions, except share price data; multiples capped at 20x EV / Revenue and 50x EV / EBITDA; net debt includes minority interest Source: Capital IQ

(1)

HealthTech (excludes Generalists)

Page 13: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

13

THE TECH REPORT: SUBSECTORS

In addition to this summary, we produce separate quarterly reports that focus specifically on; Digital Services (Digital Horizon),

Enterprise Software (Enterprise Stack), Cybersecurity (CyberScope) and Marketing Technology (MarTech Barometer). You can find

these reports on our website or by clicking on the icons below. Alternatively, you can contact one of our team members on the

details overleaf.

HEALTHTECH HEARTBEAT

CYBERSCOPE MARTECH BAROMETER

DIGITAL

HORIZONENTERPRISE

STACK

Page 14: HEALTHTECH HEARTBEAT · EV / CY Revenue Median 13.9 x 10.0x 11.0x 12.0x 13.0x 14.0x 15.0x 16.0x 17.0x EV / CY EBITDA Median LTM Q2 2018 % CHANGE Median (5.3%) (2.1%) LTM Q2 2018 %

14

GET IN TOUCH

Disclaimer: This document has been produced by Results International Group LLP (“Results”) and is furnished to you solely for your information and may not be reproduced or redistributed, in whole or in part, to any other person. No representation or warranty (expressed or implied) is made as to, and no reliance should be placed on, the fairness, accuracy or completeness of the information contained herein and, accordingly, none of Results’ officers or employees accepts any liability whatsoever arising directly or indirectly from the use of this document. Authorised and regulated by the Financial Conduct Authority.

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