human biotechnology

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    Human Biotechnology

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    Human Biotechnology

    is about you and me, notabout other creatures onEarth

    could a perfect personbe in the near future

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    Human Biotechnology

    we are not sure if we want

    one, or if we do, whattraits we would want

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    The Human Organism

    humans are similar to

    other animals, but majordifferences

    scientific name of human= Homo Sapiens

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    The Human Organism

    first Homo Sapiens on

    earth- 300,000 to400,000years ago

    each body cell of a humanhas 46 chromosomes

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    The Human Organism

    human consists of cells,tissue, organs, organsystems

    humans are primates (180

    species of animals areprimates), but still quite

    different

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    The Human Organism

    organ systems do a lot of

    work (e.g. the heart - atage of 70 it has pumped46 million gallons)

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    The Human Organism

    heart failure is leading

    cause of the human deathskeleton protects the

    internal organs

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    The Human Organism

    ligaments are tissues that

    hold the skeleton togetherskin covers the body and

    maintains the bodytemperature

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    The Human Organism

    nerve endings in skin

    sense pain, cold, heatbrain provides response to

    these conditions

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    The Human Organism

    muscles provide

    movementcells must have nutrients

    to correctly function

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    The Human Organism

    digestive system breaks foodinto useful substances

    respiratory system providesoxygen to the body and rids

    it of carbon dioxide

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    The Human Organism

    gas exchange with the

    blood occurs in the lungs

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    The Human Organism

    circulatory system (heart,blood vessels) carriesoxygen from the lungs forthe cells and brings

    wastes to the lungs andkidneys

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    The Human Organism

    urinary system removes

    certain wastes from bloodand flushes them from thebody

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    The Human Organism

    wastes move to urinarybladder and is squeezedfrom the body through theurethra

    reproductive systems varywith gender

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    The Human Organism

    mammary system

    develops in females(milk for babies)

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    Life Process

    includes growth andrepair, obtaining food andnutrients, circulation,respiration, secretion,

    sensation movement, andelimination

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    Life Process

    to stand up right, to walk

    on two legs distinguish usfrom the primates

    humans live longer anddevelop slower

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    Human Development

    is the progressivematuration of an individualfrom birth until death

    cultureconsists of the

    ways individuals havedeveloped to go about life

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    Human Development

    characteristics are

    transmitted from one toanother generation

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    Bi t h S t

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    Biotech SupportsDevelopment

    used to promote health

    ethical decisions areinvolved

    people vary about theview of biotech

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    Human Genomics

    efforts are now underway

    to identify all genomeswill allow isolation,

    treatment, replacement ofdefective ones

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    Human Genome Project

    (HGP) is an internationaleffort of involvingscientists, educators,students in locating and

    identifying every humangene

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    4 Approaches

    Genetic Mapping

    Physical MappingSequencing

    Analyzing genomes ofother species

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    4 Approaches to HGPGenetic Mapping

    Physical MappingSequencing

    Analyzing genomes ofother species

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    Background

    Canada, Italy, France, UK,USA are active

    efforts with mice, bacteria,plants

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    Background

    3 bacterial genomes havebeen completed

    progress has been morerapid than expected

    widespread use of HGPinformation in 2010

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    Findings

    genetic linkage mapshows the relativearrangement and distancebetween genes

    then DNA gets sequenced

    Helping Humans live

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    Helping Humans livebetter

    scientist have beenmanipulating genes at themolecular level

    these efforts improvehuman well being

    Helping Humans live

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    Helping Humans livebetter

    downs syndrome is adisease in which a baby isborn with an extra

    chromosome

    Helping Humans live

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    Helping Humans livebetter

    1 in 600- 800 babies isborn with it

    having a baby with downsyndrome increase withthe mothers age

    Helping Humans Live

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    Helping Humans LiveBetter

    small head, enlargedtongue, eyes that slantupward

    many die within yearno treatments available

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    Gene Therapy

    is the transfer of genes toa human organism

    make up of a human isaltered

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    Gene Therapy

    procedure is controversial

    once therapy is done, thehuman is a GMO(genetically modifiedorganism)

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    Vaccinehelp the body to recognizeand fight disease

    use weakened or killedgerms for a virus to

    introduce antigen proteinsattached to a virus

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    Vaccine

    body builds resistance

    vaccine for hepatitis ismade by inserting thegene responsible for thisantigen into yeast cells

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    Vaccine

    each yeast cell makes acopy of itself and theantigen gene

    antigen is later purified

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    Vaccine

    when injected into thebody, antigen stimulatesthe production ofantibodies that combat

    hepatitis

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    Prosthetics

    is the use of artificial partsof the human body

    includes the study and useof mechanical devises to

    replace or supplementnatural human parts

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    Prosthetics

    that includes jointreplacements, heartpeacemakers, intraocular

    lenses

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    Prosthetics

    a dialysis machineis akind of prosthesis that

    performs functions normalkidneys would do in

    removing wastes fromblood

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    Prosthetics

    biocompatibility-implanted devices must bemechanically fit for thepurpose and not rejected

    by the body

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    Prosthetics

    externally used devicesmust provide the

    appropriate mechanicalaction and support

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    Diagnostics

    is the identification of ahuman health problem or

    other conditionsknowing the approach to

    use in treating diseaserequires accurate

    diagnosis of condition Genomics and

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    Genomics andComputers

    diagnosis relies on human

    genetic informationcomputer databases are

    being used in diagnosticshelp matching genes withhealth conditions

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    Microdissection and

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    Microdissection andMolecular Analysis

    is often used to test for

    precancerous cells orinvading cancer cells

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