I Encuentro de Estudiandes de Doctorado12/06/2014

Doctoral Student: Raffaele Caroselli

Supervisor: Jaime García-Rupérez

Research Center: Nanophotonics Technology Center

Development of an integrated photonic biosensor for specific

biodetection

I Encuentro de Estudiandes de Doctorado12/06/2014

Objective

• Development of a photonic biosensor structure able to detect the lowest concentration possible of a specific target analyte

I Encuentro de Estudiandes de Doctorado12/06/2014

Real-time detection

Wav

elen

gth

shif

t

Time

Photonic sensor

Bioreceptor

Bioreceptor layer(Biolayer)

Photonic sensor

Specific Binding(Refractive Index change)

Target analyte Evanescent WaveBinding

Evanescent WaveMechanism

Δλ

I Encuentro de Estudiandes de Doctorado12/06/2014

Photonic Structure

PDMS

Opto-Fluidic Setup

Fluid

I Encuentro de Estudiandes de Doctorado12/06/2014

Possible profits

Expected Results• Real-time detection

• For the case of antigen detection, detection limits below 1 ng/ml

• Develompent of a lab-on-chip

for medical and clinical analysis

I Encuentro de Estudiandes de Doctorado12/06/2014

Thank you for the attention