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The International Federation for Medical and Biological Engineering, IFMBE, is a federation of national and transnationalorganizations representing internationally the interests of medical and biological engineering and sciences. The IFMBE is anon-profit organization fostering the creation, dissemination and application of medical and biological engineering knowledgeand the management of technology for improved health and quality of life. Its activities include participation in the formulationof public policy and the dissemination of information through publications and forums. Within the field of medical, clinical,and biological engineering, IFMBE’s aims are to encourage research and the application of knowledge, and to disseminateinformation and promote collaboration. The objectives of the IFMBE are scientific, technological, literary, and educational.

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James GohEditor

The 15th International Conferenceon Biomedical Engineering

ICBME 2013, 4th to 7th December 2013,Singapore

ABC

EditorJames GohNational University of SingaporeSingapore

ISSN 1680-0737 ISSN 1433-9277 (electronic)ISBN 978-3-319-02912-2 ISBN 978-3-319-02913-9 (eBook)DOI 10.1007/978-3-319-02913-9Springer Cham Heidelberg New York Dordrecht London

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Foreword

On behalf of the organizing committee of the International Conference on Biomedical Engineering(ICBME) 2013,we would like to warmly welcome you to this meeting. This conference is part of a series that began in 1983 andis jointly organized by the Faculty of Engineering of the National University of Singapore (NUS) and the Biomed-ical Engineering Society (Singapore) (BES). This conference is also endorsed by the International Federation forMedical and Biological Engineering (IFMBE).

We are happy to report that we have more than 600 participants from 35 countries. We have received very highquality papers and as a result, we had to decline a substantial number of papers. In this conference proceedings, wehave published 245 papers with 6 being symposium papers, 11 Young Investigator Awards (YIA) papers, 118 oralpresentation papers and 110 Poster papers. We are also very honoured to have invited very prominent speakers.Each of these speakers is an authority in their own field of expertise and we are grateful that they are able to taketime to participate in this conference.

In this conference, we have also included a design competition jointly organized by the BES and the Society ofEngineers for the Community (SEC). The focus of the competition is on the design of a low-cost medical deviceto improve healthcare in resource-scarce communities. The competition is opened to teams comprising up to fivebona-fide students. We are pleased to report that we have 12 entries from 8 countries.

While the success of this conference lies in the participation of the delegates and the quality of papers presented,we are also mindful of the efforts put in by many of the volunteers, reviewers, as well as the members of theOrganizing Committee and the International Advisory Committee. Their dedicated contributions to this meeting arevery much acknowledged and appreciated. We would also like to sincerely thank our sponsors, supporters andexhibitors for contributing to the success of this conference. Finally, we would like to thank the staff of IntegratedMeetings Specialist who has ensured the smooth running of the conference.

Finally, to all our delegates, I hope the 15th ICBME 2013 will not only be one where excellent scientific exchangesare facilitated, but also one where old friendships are renewed and new friends made. Do enjoy the conference aswell as the sights and sounds of Singapore!

Best wishes Prof. James GohChairman

Prof. Chwee Teck LIMScientific Program Chair

15th ICBME Organizing Committee

About ICBME Conference Series

The ICBME is a series of international conference in biomedical engineering held in Singapore. Our past confer-ences have been successful in attracting over 600 participants from more than 40 countries. The next conferencewill be hosted from 4-7 December 2013 in Singapore.

Biomedical engineering is applied in most aspects of our healthcare ecosystem. From electronic health recordsto diagnostic tools to therapeutic, rehabilitative and regenerative treatments, the work of biomedical engineers isevident. Biomedical engineers work at the intersection of engineering, life sciences and healthcare. The engineerswould use principles from applied science including mechanical, electrical, chemical and computer engineering to-gether with physical sciences including physics, chemistry and mathematics to apply them to biology and medicine.Applying such concepts to the human body is very much the same concepts that go into building and programminga machine. The goal is to better understand, replace or fix a target system to ultimately improve the quality ofhealthcare.

With this understanding, we have created the International Conference in BioMedical Engineering to offer asingle platform for individuals and organisations working in the biomedical engineering related field to gather andnetwork with each other in so doing create the catalyst for future development of biomedical engineering in Asia.

Organization

Organising Committee

Chairperson

James GOH

Co-Chair & Treasurer

TOH Siew Lok

Scientific Program Chair

LIM Chwee Teck

YIA Awards Chair

Sierin LIM

Student Design Competition Chair

Alberto CORRIAS

Member

Khoo-TAN Peck Ha

Member

Jeff SCHMIDT

International Advisory Committee

Taiji Adachi Kyoto UniversityKainan An Mayo ClinicCholid Badri Universitas IndonesiaGang Bao Georgia Institute of TechnologyRashid Bashir University of Illinois at Urbana-ChampaignCheng-Kung Cheng National Yang Ming UniversityShu Chien University of California, San DiegoJ.E. Davies University of TorontoYiping Du Zhejiang UniversityDavid Elad Tel Aviv UniversityRoss Ethier Georgia Institute of TechnologyJing Fan Peking UniversityYubo Fan Beihang UniversityJanie Fouke Nanyang Technological UniversityBin He University of MinnesotaHerbert Voigt Boston UniversityWalter Herzog University of Calgary

X Organization

I-Ming Hsing The Hong Kong University of Science andTechnology

Peter Hunter University of AucklandDietmar Hutmacher Queensland University of TechnologyZhonglai Jiang Shanghai Jiao Tong UniversityRoger Kamm Massachusetts Institute of TechnologyYoung-Ho Kim Yonsei UniversityEng Hin Lee National University of SingaporeKam Leong Duke UniversityKangping Lin Chung-Yuan Christian UniversityFeng Huai Lin National Taiwan UniversityHao Liu Chiba UniversityMian Long Chinese Academy of SciencesRatko Magjarevic University of ZagrebArthur Mak Chinese University of Hong KongTakeo Matsumoto Nagoya Institute of TechnologyKarol Miller University of Western AustraliaRalph Muller Eidgenössische Technische Hochschule

ZürichNigel Novell University of New South WalesTeruo Okano Tokyo Women’s Medical UniversityMarcus Pandy University of MelbourneMark Pearcy Queensland University of TechnologyRobert Ritchie University of California, BerkeleyIchiro Sakuma Tokyo UniversityMasaaki Sato Tohoku UniversityMichael Sheetz National University of SingaporeMolly Shoichet University of TorontoFong Chin Su National Cheng Kung UniversityToshiyo Tamura Osaka Electro-Communication UniversityKazuo Tanishita Waseda UniversityDavid Townsend National University Health SystemShigeo Wada Osaka UniversityJawlin Wang National Taiwan UniversityDavid F. Williams Wake Forest UniversityEd X. Wu University of Hong KongTakami Yamaguchi Tohoku UniversityAjit Yoganathan Georgia Institute of TechnologyHaishan Zeng University of British ColumbiaYuan-Ting Zhang Chinese University of Hong Kong

Scientific Program Committee

Scientific Program Chair

Chwee Teck LIM National University of Singapore, Singapore

Members

Biomedical Imaging

Anqi Qiu National University of Singapore

Organization XI

Biomedical Instrumentation

Zhiwei HUANG National University of SingaporeChangyuan YU National University of SingaporeChengkuo Lee National University of Singapore

Biosignal Processing

Nanguang Chen National University of SingaporeShanbao Tong Shanghai Jiaotong UniversityLinbo Liu Nanyang Technological University

Clinical Engineering

Peck Ha Khoo-Tan Ngee Ann Polytechnic

Neuroengineering

Shih Cheng Yen National University of SingaporeZhi Yang National University of Singapore

Telemedicine and Healthcare

Johnny Chee Ngee Ann PolytechnicKaren Chua Tan Tock Seng Hospital

Biosensors and BioMEMs

Dieter Trau National University of Singapore

Micro/Nano Biomedical Devices

Chia Hung Chen National University of Singapore

Nanobiotechnology

Yong Zhang National University of SingaporeLong Ping Wen University of Science and Technology of ChinaJames Kah National University of Singapore

Computer-Integrated and Robot-Assisted Surgery

Chee Kong Chui National University of SingaporeJimmy Liu A*Star

Ergonomics and Human Factors

Kay Chuan Tan National University of SingaporeJohn Brian Peacock National University of Singapore

Bio-Robotics

Chee Meng Chew National University of SingaporePeter Chen National University of Singapore

Rehabilitation Engineering and Assistive Technology

Hao Yong Yu National University of SingaporeDomenico Campolo Nanyang Technological UniversityYue Hong Yin Shanghai Jiaotong University

XII Organization

Artificial Organs

Hwa Liang Leo National University of SingaporeYan Wang Zhujiang Hospital & Southern Medical

University

Biomaterials

Jun Li National University of Singapore

Controlled Drug Delivery

Chi Hwa Wang National University of SingaporeYi Yan Yang A*Star

Pharmaceutical Sciences and Engineering

Sierin Lim Nanyang Technological UniversityKathy Luo Nanyang Technological University

Regenerative Medicine and Tissue Engineering

Evelyn Yim National University of SingaporeAndrew Wan A*Star

Sports Biomechanics and Human Performance

Fook Rhu Ong Singapore PolytechnicVeni Kong National Institute of Education Singapore

Cardiovascular Bioengineering

Sangho Kim National University of Singapore

Cell and Molecular Bioengineering

Pakorn Kanachawang National University of SingaporeJean-Cheng Kuo National Yang Ming University

Computational Bioengineering

Martin Buist National University of SingaporeCheng Leo University of Auckland

Dental Bioengineering

Tong Cao National University of SingaporeAmr Sherif Fawzy National University of Singapore

Organ and Tissue Mechanics

Yusuke Toyama National University of SingaporeLance Davidson University of Pittsburgh

Orthopaedic Biomechanics

Peter Lee University of MelbourneTae Yong Lee National University of Singapore

Biomedical Engineering Education

Siew Lok Toh National University of Singapore

Themes and Topics

The conference is divided into the following major themes, with its respective topics (but not limited to) as follows:

A. Bioimaging and Biosignals

1. Bioelectronics2. Biosignal Processing3. Image Guided Intervention4. Medical Imaging5. Optical Imaging

B. Biomaterials and Tissue Engineering

1. Biological Materials2. Controlled Drug Delivery3. Diagnostics and Therapeutics4. Gene Vectors Delivery5. Host Response6. Pharmaceutical Science and Engineering7. Polymer Synthesis and Characterization8. Regenerative Medicine9. Tissue Engineering

C. Biomechanics and Computational Bioengineering

1. Biomimetics2. Cardiovascular Mechanics3. Cell Mechanics4. Computational Mechanics5. Insect and Animal Biomechanics6. Mechanobiology7. Molecular Biomechanics8. Musculoskeletal Mechanics9. Orthopaedics

10. Tissue Mechanics11. Organ Mechanics

D. Biomedical Devices and Biomedical Instrumentation

1. Biochips2. Biomedical Devices3. BioMEMS4. Diagnostic Devices5. Implantable Devices6. Lab-on-Chip7. Microarrays8. Micro/Nanofabrication

XIV Themes and Topics

9. Micro/Nanofluidics10. Micro-Total Analysis Systems11. Organ-on-Chip12. Surgical Tools

E. Biomedical Robotics and Surgical Technology

1. Assisted Technologies2. Bio- and Medical Robotics3. Bioinstrumentation and Control4. Rehabilitation5. Soft Robotics

F. Neuroengineering and Rehabilitation Engineering

1. Clinical and Translational Neuroengineering2. Cognitive Engineering3. Neurotechnology4. Neurotherapeutics

G. Special Topics

1. Bioethics2. Biomedical Engineering Education3. Manuscript Writing

Conference Lecture Speaker

Stephen Quake

Professor of BioengineeringInvestigator, Howard Hughes Medical InstituteStanford University

Plenary Speakers

Professor Rashid BashirDepartment of Electrical and Computing EngineeringUniversity of IllinoisBiomedical Micro and Nanotechnology: From Lab-on-Chip to Building Systems with Cells

Professor Gerhard A. HolzapfelInstitute of BiomechanicsGraz University of TechnologyBiomechanics of Arterial Walls in Health and Disease: State of the Art and Challenges Ahead

Professor Antonios G. MikosJohn W. Cox Laboratory of Biomedical EngineeringCenter for Excellence in Tissue EngineeringRice UniversityBiomaterials for Tissue Engineering

Professor Ichiro SakumaDepartment of Precision Engineering/Department of BioengineeringSchool of Engineering, The University of TokyoIntegration of Computer Assisted Surgical Guidance and Surgical Robotics for Minimally Invasive Surgery

Professor Geert Schmid-SchoenbeinBioengineeringUCSD Jacob School of BioengineeringAutodigestion: A Missing Link to Inflammation and Disease

Professor Nitish ThakorDepartment of Electrical and Computer Engineering/Department of Bioengineering/Department of MedicineFaculty of Engineering, National University of SingaporeBrain Machine Interface Technology: from Neurons to Prostheses

Professor David TownsendDirectorA*STAR-NUS Clinical Imaging Research Centre (CIRC)Advancing Multi-Modality Clinical Imaging: a Challenge for the Engineer and Physicist

Keynote Speakers

Kishore BhakooSingapore Bioimaging ConsortiumApplication of Bioimaging to Tissue Engineering and Regenerative Medicine

Theodoros KofidisNational University Hospital

Robert HoffmanUniversity of California, San DiegoNestin-Expressing Multipotent Hair Follicle Stem Cells for Regenerative Medicine

I-Ming HsingThe Hong Kong University of Science & TechnologyElectrochemistry and Nanotechnology in Biomicrosystems for Point of Care Applications

Peter HunterUniversity of AucklandAn overview of VPH/Physiome activities

Oussama KhatibStanford UniversityRobots and the Human

Hong Wei OuyangZhejiang UniversityCurrent Biomaterials for Tendon / Ligmaent Tissue Engineering

Louis PheeNanyang Technological UniversityRobotics in Gastroenterology: Bench to Beside, and Beyond

Michael SheetzNational University of Singapore

Yasuhiko TabataKyoto UniversityDrug Delivery Technology for Tissue Regeneration Therapy

Jaw-Lin WangNational Taiwan UniversityDevelopment, Validation of a Degenerated Intervertebral Disc Model and its Application in Disc Research

Christopher WongGenome Institute of Singapore

Edward X WuUniversity of Hong Kong

Symposia

Symposium Chair Co-ChairsGastrointestinal Motility Martin Buist

National University of SingaporeLeo ChengUniversity of Auckland

Reproductive Bioengineering David EladTel Aviv University

Pharmaceutical Science andEngineering

Sierin LimNanyang Technological University

Kathy Luo QianNanyang Technological University

Micro and Nanofluidics forBiomedical Applications

Lim Chwee TeckNational University of Singapore

Dino Di CarloThe University California, San Diego

Jay HanMassachusetts Institute of Technology

Biomedical Engineering in SportScience

Matthias LochmannInstitut für Sportwissenschaft und Sport

Supramolecular and Nano-Biomaterials

Li JunNational University of Singapore

Biomechanics in Nature andBioinspired Engineering

Liu HaoChiba University

Masatsugu ShimomuraTohoku University

Musculoskeletal Tissue Engineering Lee Eng HinNational University of Singapore

Virtual Physiological Rat Project David NickersonThe University of Auckland

Tissue Mechanobiology: Tissue onthe move

Yusuke ToyamaNational University of Singapore

Nanoparticles for Bioimaging andTargeted Therapy

Zhang YongNational University of Singapore

James KahNational University of Singapore

Table of Contents

Symposium Presentation

Ultra-High Throughput Enrichment of Viable Circulating Tumor Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1B.L. Khoo, M.E. Warkiani, Guofeng Guan, Daniel Shao-Weng Tan, Alvin S.T. Lim, Wan-Teck Lim, Yoon Sim Yap, Soo Chin Lee,Ross A. Soo, Jongyoon Han, Chwee Teck Lim

An Image-Based Model of the Interstitial Cells of Cajal Network in the Gastrointestinal Tract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5Ruchi J. Vyas, Jerry Gao, Leo K. Cheng, Peng Du

Pillararenes: Easy-to-Make and Versatile Receptors for Supramolecular Chemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9T. Ogoshi

An Interdisciplinary Approach to Understanding Gastrointestinal Slow Wave Electrophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12P. Du, Leo K. Cheng

A Biophysically-Based Tissue Model for Optimizing Gastric Pacing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16S. Sathar, G. O’Grady, M.L. Trew, Leo K. Cheng

Sliding Graft Copolymers – Supramolecular Derivatives Equipping Promising Potentials – . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20Jun Araki

Young Investigator Award

Synchrotron Nano-Mechanical Imaging Techniques to Understand How Altered Bone Quality Increases Fracture Risk in SecondaryOsteoporosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24

A. Karunaratne, L. Bentley, R. Cox, A. Boyde, C.T. Esapa, N.J. Terrill, G.R. Davis, S.D.M. Brown, R.V. Thakker, H.S. Gupta

Design and Actuation of a Snake-Like Robot for Minimally Invasive Surgeries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28Zeqi Tan, Hongliang Ren

Correlation between Facial Trauma and Brain Injury – A Finite Element Study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32Kwong Ming Tse, Long Bin Tan, Shu Jin Lee, Siak Piang Lim, Heow Pueh Lee

Understanding Nanotopography Induced Stem Cell Differentiation: A Focus on Focal Adhesion Kinase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36Benjamin Kim Kiat Teo, Sum Thai Wong, Choon Kiat Lim, Terrence Y.S. Kung, Chong Hao Yap, Yamini Ramgopal, Lewis H. Romer,Evelyn K.F. Yim

Optimal Intra-articular Injection of Parathyroid Hormone-Related Protein Effectively Promotes Osteochondral Defects Repair . . . . . . . . . . . 40Wei Zhang, Jialin Chen, Jiadong Tao, Changchang Hu, Junfeng Ji, Hong Wei Ouyang

Relationship between Pathology and Hemodynamics of Human Unruptured Cerebral Aneurysms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44Yasutaka Tobe, Takanobu Yagi, Yuki Iwabuchi, Momoko Yamanashi, Kenji Takamura, Takuma Sugiura, Mitsuo Umezu,Yoshifumi Hayashi, Hirotaka Yoshida, Atsushi Nakajima, Kazutoshi Nishitani, Yoshifumi Okada, Michihito Sugawara, Shin Hiraguchi,Toshiro Kubo, Shigemi Kitahara

Estimation of Changes in Mechanical Bone Quality by Multi-scale Analysis with Remodeling Simulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48D. Tawara, K. Nagura, T. Tsujikami, T. Adachi

A Biophysically-Based Tissue Model for Optimizing Gastric Pacing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52S. Sathar, G. O’Grady, M.L. Trew, Leo K. Cheng

Porohyperelastic Analysis of Single Osteocyte Using AFM and Inverse FEA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56Trung Dung Nguyen, Adekunle Oloyede, Sanjleena Singh, Yuantong Gu

XX Table of Contents

Effect of Spatial Arrangement of Substrate Topography on Neuronal Differentiation of Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60Evelyn K.F. Yim, S. Ankam, A.A.K. Moe, L.Y.T. Chan

Ligament-to-bone Interface Tissue Regeneration Using a Functionalized Biphasic Silk Fibroin Scaffold . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64T.K.H. Teh, P. Shi, X. Ren, J.H.P. Hui, S.L. Toh, J.C.H. Goh

Oral Presentation – Bioimaging and Biosignals

Assessment of First Derivative of Doppler Blood Flow Velocity in Vascular Aging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68H. Zulaika, A. Azhim, M. Saleh, P. Baghepour, Y. Kinouchi, F. Ibrahim

SAR Computation and Channel Modeling of Body Area Networks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72Zhang-yong Li, Yu Pang, Jinzhao Lin, Jie Liu, Shengrong Liu, Chun-yang Li

A Method for Automatic Delineation of the Left Ventricle Borders in Echographic Images with Use Active Contours and Speckle TrackingTechniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76

S.Yu. Sokolov, F.A. Blyakhman

Phase Detection for Electric Field Body Scanner . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80I. Hieda, K.C. Nam

Automated Parameter Estimation for a Nonlinear Signal Separation Scheme . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84Y. Yao, S. van Waasen, M. Schiek

Efficient Regularization of Temporal Autocorrelation Estimates in fMRI Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88Arun Kumar, Lin Feng

Remote Photopletysmographic Imaging of Dermal Perfusion in a Porcine Animal Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92N. Blanik, C. Pereira, M. Czaplik, V. Blazek, S. Leonhardt

Effect of Treatment Using 3-Dimentional Disease Generating Model on Optical Coherence Tomography Images . . . . . . . . . . . . . . . . . . . . . 96Ngoc Anh Huyen Nguyen, Shinji Tsuruoka, Haruhiko Takase, Hiroharu Kawanaka, Hisashi Matsubara, Hisanori Yagami,Fumio Okuyama

Design and Implementation of a Calibration – Free Pulse Oximeter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100H. Harini, L.S. Krithika, M. Shalini, Sirisha Swaminathan, N. Madhu Mohan

Aging Integromics: Module-Based Markers of Heart Aging from Multi-omics Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104Konstantina Dimitrakopoulou, Aristidis G. Vrahatis, Georgios N. Dimitrakopoulos, Anastasios Bezerianos

Theoretical Study of Non-equilibrium Ionic Response Near Electrode Surface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108K. Doi, M. Tsutsui, T. Ohshiro, M. Taniguchi, T. Kawai, M. Di Ventra, S. Kawano

Region Growing for Medical Image Segmentation Using a Modified Multiple-seed Approach on a Multi-core CPU Computer . . . . . . . . . . . 112Agus Pratondo, Sim Heng Ong, Chee Kong Chui

Measurement of Undetectable Walking Feature by Appearance Based on Plantar Skin Deformation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116Takayuki Shiina, Akira Obara, Hiroshi Takemura, Hiroshi Mizoguchi

Gastric Lymph Node Cancer Detection Using Multiple Features Support Vector Machine for Pathology Diagnosis Support System . . . . . . 120T. Ishikawa, J. Takahashi, Hiroshi Takemura, Hiroshi Mizoguchi, T. Kuwata

An Adaptable Inertial Sensor Fusion-Based Approach for Energy Expenditure Estimation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124D. Schuldhaus, S. Dorn, Heike Leutheuser, A. Tallner, J. Klucken, Bjoern M. Eskofier

Development of Novel Endoscope with NIR Camera Using Real-time Video Composite Method . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128Masayuki Watanabe, Hiroshi Takemura, Hiroshi Mizoguchi, Hiroshi Hyodo, Kohei Soga, Tamotsu Zako, Hidehiro Kishimoto,Masaaki Ito, Kazuhiro Kaneko

SVM for Semi-automatic Selection of ICA Components of Electromyogenic Artifacts in EEG Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132Florian Gabsteiger, Heike Leutheuser, Pedro Reis, Matthias Lochmann, Bjoern M. Eskofier

Table of Contents XXI

Hierarchical Identification Process of a Two-Parameter Gas Exchange Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136A. Riedlinger, J. Kretschmer, K. Möller

CT Image Reconstruction Algorithm to Reduce Metal Artifact . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140Toru Kano, Michihiko Koseki

Assigning Myocardial Fibre Orientation to a Computational Biventricular Human Heart Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144A. Palit, G.A. Turley, S.K. Bhudia, R. Wellings, M.A. Williams

Strategies for Baseline Drift Compensation of DC-Coupled Electrooculagram Measurements for Human-Computer-Interfaces . . . . . . . . . . 148A. Böhm, A. Uhlig, S. Leonhardt

A Dynamic Liver Phantom for Ultrasound Image Guided Biopsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152Liu Li, S.P. Ang, J. Liu, Haoyong Yu

Viscoelastic Properties of Gel Material and Soft Tissue Measured by MRE (Magnetic Resonance Elastography) Using Micro MRE . . . . . . 156Hayato Suzuki, Mikio Suga, Kazuhiro Fujisaki, Itsuro Kajiwara, Gen Nakamura, Kogo Yoshikawa, Shigeru Tadano

Acoustic Cochlear Implant Models Incorporating Electrical Field Interaction between Neighboring Electrodes . . . . . . . . . . . . . . . . . . . . . . . . 160C.T.M. Choi, S.Y. Huang, Y.H. Lee

Automatic Cervical Cell Classification Using Patch-Based Fuzzy Clustering and Minimum Average Correlation Energy Filter . . . . . . . . . . . 164Thanatip Chankong, Nipon Theera-Umpon, Sansanee Auephanwiriyakul

MRE Simulation Based on Finite Element Vibration Analysis of Viscoelastic Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168S. Tomita, Hayato Suzuki, Itsuro Kajiwara, Shigeru Tadano, Gen Nakamura, Y. Jiang

3-D Lung Visualization Using Electrical Impedance Tomography Combined with Body Plethysmography . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172S. Heizmann, M. Baumgärtner, S. Krüger-Ziolek, Z. Zhao, K. Möller

Measurements and Data Processing in Home Care Telemetry Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176Marek Penhaker, H. Tran Minh

Multiclass Least-Square Support Vector Machine for Myoelectric-Based Facial Gesture Recognition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180M. Hamedi, Sh-Hussain Salleh, A.M. Noor, Arief R. Harris, N.A. Majid

A Study on the High-Resolution Imaging System for Capillary on the Surface of Eyeball . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184Jiamao Li, Xiaolin Zhang

Liver Vessel Segmentation Using Graph Cuts with Quick Shift Initialization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188Bichao Chen, Ying Sun, Sim Heng Ong

Effect of Mobile Phone Radiation on Brain Using Wavelet Energy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192C.K. Smitha, N.K. Narayanan

Creation of the Beam Hardening Artifact . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196Jan Kubícek

The Development of Behavioral and Neuronal Activities of Animal Models with Kindling-induced and Spontaneous Temporal LobeSeizures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199

Yu-Lin Wang, Yin-Lin Chen, Yu-Shin Huang, Sheng-Fu Liang, Fu-Zen Shaw

Diagnosis of Schizophrenia Patients Based on Brain Network Complexity Analysis of Resting-State fMRI . . . . . . . . . . . . . . . . . . . . . . . . . . . 203Tsung-Hao Hsieh, Ming-Jian Sun, Sheng-Fu Liang

Analysis of SELDI-TOF-MS Using ε-Support Vector Regression for Ovarian Cancer Identification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207Isye Arieshanti, Yudhi Purwananto

A Modified Synthetic Aperture Focusing Technique Using Beam Characteristics of Transducer for Ultrasound Image Improvement . . . . . . 211Chia-Che Ho, Yi-Hsun Lin, Shyh-Hau Wang

XXII Table of Contents

Automatic Detection of Atrial Fibrillation Using RR Interval from ECG Signals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215V. Gokana, C.T. Phua, G. Lissorgues

Optimization of Non Adaptive Mechanical Ventilation by Analyzing Electrical Impedance Tomography Images Using Advance StatisticalMethods as Analytic Tool . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219

Syedah Sadaf Zehra, Syed Ahsan Ali, Syed Mohsin S. Kazmi, Saima Hayat, Inam Ul Ahad

Classification of EEG Signals from Imagined Writing for Treating Writing Disorder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223A. Zabidi, W. Mansor, Y.L. Khuan, C.W.N. Che Wan Fadzal

Design and Evaluation of a Hardware-Accelerator for Energy Efficient Inertial Sensor Fusion on Heterogeneous SoC Architectures . . . . . 227H.-P. Brückner, C. Spindeldreier, H. Blume

Semi Automatic Segmentation of Breast Thermograms Using Variational Level Set Method . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231S.S. Suganthi, S. Ramakrishnan

ELM Based Classification and Analysis of Spirometric Pulmonary Function Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235A. Mythili, C.M. Sujatha, S. Srinivasan

Oral Presentation – Biomaterials and Tissue Engineering

Effect of Biphasic Calcium Phosphate Treated with Vascular Endothelial Growth Factor on Osteogenesis and Angiogenesis GeneExpression In Vitro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239

H E. Hamid, A. Azlina, M.F. Khamis, R.A. Rahman, N.H. Abdul Razak, S.S. Mutum, A.R. Samsudin

Evaluation of Particle Deposition Efficiency in Human Oral Passage: A CFD Study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243J.H. Zhu, H.S. How, D.Y. Wang, Shu Jin Lee, Heow Pueh Lee

Effect of the Polyelectrolyte Hydrogel Actuator Network Density on Its Mechanical Behavior in the DC Electric Field . . . . . . . . . . . . . . . . . . 247M.A. Filipovich, T.F. Shklyar, A.P. Safronov, S.Yu. Sokolov, F.A. Blyakhman

Nano-Scale Thermo-Mechanical Structure-Property Relationships in Human Dental Tissues Studied by Nanoindentation and SynchrotronX-Ray Scattering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251

T. Sui, M.A. Sandholzer, E.L. Bourhis, N. Baimpas, G. Landini, A.M. Korsunsky

Hyperelastic Constitutive Relationship for the Strain-Rate Dependent Behavior of Shoulder and Other Joint Cartilages . . . . . . . . . . . . . . . . 255N. Thibbotuwawa, Adekunle Oloyede, W. Senadeera, Yuantong Gu

Synthesizing Gold Nanoparticles in Spherical and Rod Shapes for Targeting Cancer Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259G.F. Chin, M. Misran, P.Y. Tang, P.F. Lee

Development of Cartilaginous Tissue in Chondrocyte-Agarose Construct Cultured under Traction Loading . . . . . . . . . . . . . . . . . . . . . . . . . . 263Fukuda Keisuke, Omata Seiji, Sawae Yoshinori

Polycarpolactone Fibers Gellation with Gelatin Ground Substance: Engineered Skin Extracellular Matrix Aims for Using as TissueEngineering Skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267

O. Chaisiri, N. Chanunpanich, B.S. Hanpanich

Guidelines for Modelling BED in Simultaneous Radiotherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271Jan Kubícek, Marek Penhaker

Immune Response of Implanted Aortic Scaffolds Decellularized by Sonication Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275N. Syazwani, A. Azhim, Y. Morimoto, K. Furukawa, T. Ushida

Proliferation Behavior of Mesenchymal Stem Cells in Peptide Functionalized Chitosan Scaffolds . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279Md. Abdul Kafi, Yos Phanny, Yusuke Nakamuta, Mitsugu Todo

Mechanical Variation and Proliferation Behavior in Hydroxyapatite Based Scaffolds with Mesenchymal Stem Cells . . . . . . . . . . . . . . . . . . . 283Phanny Yos, Md. Abdul Kafi, Mitsugu Todo

Table of Contents XXIII

A Pervasive Intelligent System for Scoring MEWS and TISS-28 in Intensive Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287Filipe Portela, Manuel Filipe Santos, Álvaro Silva, José Machado, António Abelha, Fernando Rua

Oral Presentation – Biomechanics and Computational Bioengineering

Predicting the Contact of Dual Mobility Hip Implants – Effect of Bearing Geometry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291M.S. Uddin

Computational Study on the Effect of the Ligaments in Knee Joint during Quasi-Static Stand-to-Sit Motion . . . . . . . . . . . . . . . . . . . . . . . . . . 295C. Chung, B.-S. Yang

On the Roles of Actin Stress Fibers on the Mechanical Regulation of Nucleus in Adherent Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299K. Nagayama, Y. Yahiro, S. Yamazaki, M. Ukiki, T. Matsumoto

Accurate Modelling of Finger Kinematics Using a Statistically-Reduced Rigid Body Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303K. Mithraratne, T. Wu

A Realistic Subject-Specific Finite Element Model of Human Head-Development and Experimental Validation . . . . . . . . . . . . . . . . . . . . . . . 307Kwong Ming Tse, Long Bin Tan, Shu Jin Lee, Siak Piang Lim, Heow Pueh Lee

Effects of Adduction, Internal Rotation, and Flexion Angles on Dislocation for Total Hip Arthroplasty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311M. Higa, H. Tanino, Y. Yamagami, M. Abo, S. Kakunai

Observation of Filling Process in Injection Molding for Fabrication of Bone Biomodel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315Masashi Ohtake, Kei Ozawa, Makoto Ohta

Viscoelastic Property and Cell Adhesion Process of Cultured Fibroblasts on Different Self-assembled Monolayers Monitored by AcousticWave Biosensor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319

Y. Viturawong, S. Chongthammakun, N. Niamsiri, Toemsak Srikhirin, T. Osotchan

Investigation of Determinants of Atypical Femoral Fractures Using Multiscale Computational Modeling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 323S. Martelli, P. Pivonka, P.R. Ebeling

Langevin Dynamics Simulation of Single-Stranded DNA Translocation though Nanopore in External Non-uniform Electric Field . . . . . . . . . 327W. Qian, K. Doi, S. Kawano

Biomechanics of Artificial Elbow Joints . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 331Norio Inou, Michael Surjawidjaja, Kobayashi Katsunori, Taisuke Osanai, Ren Kadowaki, Hitoshi Kimura, Jun Ikeda, Katsunori Inagaki

In-silico Study of the Nasal Cavity’s Influence on the Pharyngeal Wall Pressure in Anatomically-Correct Airway Models of Patients withObstructive Sleep Apnea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335

J. Cisonni, A.D. Lucey, A.J.C. King, S.M.S. Islam, M.S. Goonewardene

Response of a Femoral Bone to Stationary and Continuous Load from within Outward . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 339K. Mabuchi, K. Uchida, T. Ito, R. Sakai, K. Naruse

Blood Flow Analysis in Patient-Specific Cerebral Aneurysm Models with Realistic Configuration of Embolized Coils . . . . . . . . . . . . . . . . . . . 343T. Otani, S. Ii, T. Fujinaka, M. Hirata, J. Kuroda, K. Shibano, Shigeo Wada

Mechanical Analysis of Mineral and Collagen Phases in Bone by Raman Spectroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347M. Todoh, Shigeru Tadano

Muscle Force Prediction during Knee Flexion/Extension Using EMG-Driven Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349Saran Keeratihattayakorn, Shigeru Tadano

Design Optimization of Thoracic Endovascular Stent Graft (EVSG) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352Kiruthigha Shanmugam, N. Viswanatha, R.K. Ramanathan, Johanna Rajan, Suvita Selvam, Mohan Thanikachalam

Simulation of Photon Propagation in Multi-layered Tissue for Non-Invasive Fetal Pulse Oximetry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356S. Ley, D. Laqua, P. Husar

XXIV Table of Contents

Visual Haptic-based Collaborative Molecular Docking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360X. Hou, Olga Sourina, S. Klimenko

Effects of the Position of Tongue on the Sound Generation of Sibilant/S/ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364T. Yoshinaga, K. Nozaki, Shigeo Wada

An Anatomically Realistic Geometrical Model of the Intra-epidermal Nerves in the Human Foot . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368M.Z. Ul Haque, P. Du, Leo K. Cheng, M.D. Jacobs

Achievement of Peristaltic Design in the Artificial Esophagus Based on Esophageal Characteristic Analysis of Goats’ Specimen . . . . . . . . 372Y. Taira, K. Kamiya, Y. Shiraishi, H. Miura, T. Shiga, Mohamed O. Hashem, A. Yamada, Y. Tsuboko, T. Ito, K. Sano, D. Homma, T. Yambe

Hemodynamic Studies of Flow Modulating Stent Designs for Aortic Aneurysms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375S.L. Yeow, H. L Leo, T.Y.R. Hong, W.C.M. Loh, S.Y. B Chua

Assessment of the Impact of Positive Heels (Plantarflexion) and Negative Heels (Dorsiflexion) Shoes on Human Walking Gait . . . . . . . . . . 379E.X. Ng, C. Monkhouse, P. Wong, G. Meyer, Y. Aloni, D.Y.R. Chong

Influence of Contact Angle on the Bubble Transport in a Rectangular Bifurcating Microchannel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 383J. Poornima, S. Vengadesan

Influence of Lower-Leg Muscle Spindle Function in Irregular Surface Walking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387Obara Akira, Yamakoshi Takeshi, Shina Takayuki, Takkemura Hiroshi, Mizoguchi Hiroshi

A Study of Mechanical Behavior of an Encapsulated Stent Design Using Finite Element Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391Kiruthigha Shanmuga Sundaram, Davidson Jebaseelan, Rince Jose, Ranjitha Rebecca Jeevan, George Joseph, Santhosh Jospeh,Mohan Thanikachalan

Wearable Movement Analysis System for Children with Movement Disorders - Lower Extremities Assessment System . . . . . . . . . . . . . . . . 395Chong Yu Zheng, Jasmy Yunus

Improvement of a Shape Memory Alloy Fibered Aortic Pulsation Device . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399Mohamed O. Hashem, Y. Shiraishi, A. Yamada, Y. Tsuboko, H. Muira, T. Yambe, D. Homma

Numerical Investigation of Micro-particle Transport and Deposition in an Upper Airway Considering Human Workloads . . . . . . . . . . . . . . . . 403K.H. Sung, J.T. Kim, H.S. Ryou

Oral Presentation – Biomedical Devices and Biomedical Instrumentation

Qualitative Studies on Quartz Filters Used in Ultraviolet Sterilization System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 407Ravichandran Subbaraman, Then Tze Kang

Embedded Fuzzy Classifier for Detection and Classification of Preseizure State Using Real EEG Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411Uvais Qidwai, Aamir Saeed Malik, Mohamed Shakir

Challenges and Trade-Offs Involved in Designing Embedded Algorithms for a Low-Power Wearable Wireless Monitor . . . . . . . . . . . . . . . . . 416M.A. Hernandez-Silveira, S.S. Ang, A. Burdett

Multi-objective Design Optimization for a Steerable Needle for Soft Tissue Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420Alexander Leibinger, Matthew Oldfield, Ferdinando Rodriguez y Baena

Micro-fabricated Membranes with Regular Pores for Efficient Pathogen Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424M.E. Warkiani, H.Q. Gong

High Sensitive Detection of Ag+ Ions in Aqueous Solution Using Silicon Nanowires and Silver-Specific Oligonucleotide . . . . . . . . . . . . . . . 428Yu Chen, Muhammad Hamidullah

Characterization of the Role of Contact Surface Temperature on the Perception of Hand-Transmitted Vibrations . . . . . . . . . . . . . . . . . . . . . . 432Manabu Chikai, Mohammad A. Fard, Hitoshi Miyake

Table of Contents XXV

Pressure Distribution Measurement of Close Fitting Clothes on Human Body . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436J. Grepl, Marek Penhaker, J. Kubicek, J. Prokop, L. Peter

Design of a Right Ventricular Simulator for the Evaluation of Artificial Pulmonary Valve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440Y. Tsuboko, S. Matsuo, Y. Shiraishi, H. Miura, A. Yamada, Mohamed O. Hashem, T. Ito, K. Sano, Y. Taira, T. Akutsu, Z. Feng,Mitsuo Umezu, M. Yamagishi, Y. Saiki, T. Yambe

Preliminary Study on Contactless Evaluation of Peripheral Perfusion during Rotary Blood Pump Support . . . . . . . . . . . . . . . . . . . . . . . . . . . 444K. Sano, T. Kitano, Y. Shiraishi, A. Tanaka, M. Yoshizawa, T. Yambe

Modeling of Signal Transmissions in Nerves in Vitro for the Development of a Renal Nerve Cooling Device for Hypertension Control . . . . . 448T. Ito, H. Miura, T. Shiga, Mohamed O. Hashem, K. Kamiya, A. Yamada, Y. Tsuboko, K. Sano, Y. Taira, Y. Shiraishi, H. Kumagai,T. Yambe

Development of Seizure Monitoring and Control Systems for Epileptic Animal Models . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452Sheng-Fu Liang, Yu-Lin Wang, Fu-Zen Shaw

Carbon Nanotubes as a Cradle of Impulse for Implantable Medical Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456Fredrick Johnson J., Karthick M., Sathiesh Kumar S., Gopu G.

Oral Presentation – Biomedical Robotics and Surgical Technology

Development and Testing of a Visuo-Haptic Surgical Training Simulator for Orthognathic Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460Lin Yanping, Chen Xiaojun, Wang Xudong, Shen Guofang, Wang Chengtao

An Automatic System for Batch Microinjection of Silkworm Eggs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464Hian Hian See, Shengfeng Zhou, Daiwen Yang, Peter C.Y. Chen

Modeling of Bioimpedance Spectroscopy Measurements for the Process Control of an Orthopedic Surgical Milling Tool . . . . . . . . . . . . . . . 468C. Brendle, A. Niesche, A. Korff, K. Radermacher, B. Rein, A. Scholl, B. Misgeld, S. Leonhardt

A Multi-level Fuzzy Logic System for Controlling the Tibialis Anterior FES Envelop . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 472N. Zakhirehdari, H.R. kobravi, M. Masoudi, P. Tavakkoli

Effects of Muscle Fatigue on FES Assisted Walking of SCI Patients: A Review . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 476M.O. Ibitoye, N.A. Hamzaid, A.K. AbdulWahab

Investigating Multimodal Displays: Reaction Times to Visual and Tactile Modality Stimuli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 480J. Yu, K. Möller

VASST: Variable-Speed Sensing Treadmill for Gait Retraining after Stroke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484Johnny Chee, K.S.G. Chua, W.S. Yu, W.S. Ong, C.M. Hoo, P.H. Lim, W.S. Lim

Energy Recovery Concept for Collecting Stochastic Occurring Power Chunks to Supply Intermittent Sensor Measurements on Prosthesesor Robotic Limb . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488

D. Laqua, P. Husar

Performance Evaluation of Novel Ankle-Foot Assist Device for Ankle-Foot Rehabilitation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492Takayuki Onodera, Ming Ding, Hiroshi Takemura, Hiroshi Mizoguchi

Measuring Human Balance on an Instrumented Dynamic Platform: A Postural Sway Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496Darwin Gouwanda, Alpha A. Gopalai, Z.S. Lim, K.H. Lim

Integrated RF and Cryo ablation of Liver Tumor for Computer Integrated Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500Duan Bin, Chui Chee Kong, Chua Kian Jon, Ernest

Signal Analysis and System Identification of an Active Mechanical Lung Simulator in Order to Design a Control Regime . . . . . . . . . . . . . . . 504T. Laechele, T. Zifreund, C. Knoebel, K. Moeller

A Head Tracking Method for Improved Eye Movement Detection in Children . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 508M. Sangi, B. Thompson, E. Vaghefi, J. Turuwhenua

XXVI Table of Contents

Supine Gait Training Device for Stroke Rehabilitation – Design of a Compliant Ankle Orthosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 512Fang Ming Lim, Ruyi Foong, Kay Sin Goh, Qing Lin Mok, Beng Hao Jasper Tan, Soon Leng Toh, Haoyong Yu

Design and Development of Lower Limb Exoskeleton for Rehabilitation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516V. Yugan, Suresh Gobee, D. Vickneswari

Finger Grip Rehabilitation Using Exoskeleton with Grip Force Feedback . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 520C.L. Chan, Suresh Gobee, D. Vickneswari

Prospects of Mechanomyography (MMG) in Muscle Function Assessment during FES Evoked Contraction: A Review . . . . . . . . . . . . . . . . . 524M.O. Ibitoye, N.A. Hamzaid, A.K. AbdulWahab

Oral Presentation – Neuroengineering and Rehabilitation Engineering

EEG-Based Emotion Monitoring in Mental Task Performance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527Yisi Liu, Olga Sourina, Woon Huei Chai

Oral Presentation – Special Topics

Education of Biomedical Engineering in the Technical University of Ostrava . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531M. Augustynek, Marek Penhaker, M. Cerny, J. Cernohorsky, I. Bryjova

Poster Presentation – Bioimaging and Biosignals

A Forward-Backward Subsequence Smoothing Based Eigen Approach to Clutter Rejection in Color Flow Imaging . . . . . . . . . . . . . . . . . . . . 535Z. Shen, N. Zhang, Y. Shen, C.-H. Lee

Validation of Algorithm with Noise Tolerance Methods to Detect R-wave . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 539Won Kyu Lee, Hong Ji Lee, Jeong Su Lee, Hee Nam Yoon, Soo Young Sim, Yong Gyu Lim, Kwang Suk Park

Brainwave Sub-band Power Spectral Density Characteristics for Human Brain Balanced via Three Dimensional ElectroencephalographicModel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 543

N. Fuad, M.N. Taib, A.H. Jahidin, R. Mohd Isa, M.E. Marwan

The Research of High-Speed Data Caching Algorithm in the CCD/DR System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 547Jie Liu, Zhang-yong Li, Li-fang Zhang, Chun-yang Li

Feature Evaluation of Flow Limitation in Obstructive Sleep Apnea Cases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 551Kang Ping Lin, Po-Chung Shih, Keng Hung Lin, Wen Chen Lin, Ching Liang Yu, Yun Yueh Liu, Ya Ting Shih, Sheng Cheng Huang,Yu-Ju Chiang

The Autonomic Nervous System Functions in Integrated Circuit Design Company Employees during Different Working Time . . . . . . . . . . . 555Chih-Yuan Chuang, Cheng-Nan Tsai, Ming-Tsan Kao, Sen H. Huang

Highly Integrated, Low Cost, Palm-Top Sized Magnetic Resonance Relaxometry System for Rapid Blood Screening . . . . . . . . . . . . . . . . . . 558Nhat Nguyen Vo, Lan Chen, Xuening Liu, Weng Kung Peng, Zhou Yi Ming, Jongyoon Han

Effects of Massage Therapy Intervention on Autonomic Nervous System Promotion in Integrated Circuit Design Company Employees . . . 562Chih-Yuan Chuang, Cheng-Nan Tsai, Ming-Tsan Kao, Sen H. Huang

Classification of Evoked Potentials Associated with Error Observation Using Artificial Neural Networks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 565P. Asvestas, E.M. Ventouras, G.K. Matsopoulos, I. Karanasiou

Recognition of Korean Monosyllabic Speech Using 3D Facial Motion Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 569D.W. Kang, J.S. Choi, J.H. Bae, Y.H. Shin, J.H. Lee, J.B. Choi, G.R. Tack

A Hierarchical Model Family of Human Gas Exchange for the Use in Medical Decision Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573J. Kretschmer, A. Riedlinger, K. Möller

Table of Contents XXVII

Multiple Classifier System Applied to the Control of Bioprosthetic Hand Based on Recognition of Multimodal Biosignals . . . . . . . . . . . . . . . 577M. Kurzynski, A. Wolczowski

Improved Algorithm of Adaptive DR Image Denoising Based on Fast Curvelet Transform and Anisotropic Median-diffusion Filtering . . . . . 581Li-fang Zhang, Zhang-yong Li, Jie Liu, Chun-yang Li

Scalability Tower Multi-scale DR Image Enhancement Algorithm Based on Human Visual Characteristics . . . . . . . . . . . . . . . . . . . . . . . . . . . 585Li-fang Zhang, Zhang-yong Li, Jie Liu, Chun-yang Li

Investigation of Significant Attributes Based on Image Feature and Texture Analysis for Automatic Noise Reduction in MRI . . . . . . . . . . . . 589Yu-Ju Lin, Herng-Hua Chang

Computer-aided Technique for the Design and Manufacturing of Auricular Prostheses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593T. Murayama, M. Ogasawara, T. Eguchi, Y. Morishita, M. Tamamoto

Brain Extraction Based on an Improved Charged Fluid Model in MRI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597Yu-Sheng Chen, Herng-Hua Chang

Measurement of the Orientation of 2D Ultrasound Probe for Medical Diagnosis of Left Ventricular Motion . . . . . . . . . . . . . . . . . . . . . . . . . . . 601Y. Inui, Hitoshi Kimura, Norio Inou, K. Sakata, Y. Nakajima

Application of List Mode Image Reconstruction to Fine DOI-PET Scanner Using Position-Sensitive CdTe Semiconductor Detector Unit . . . 605Yohei Kikuchi, Abdella Ahmed

Low Frequency Acoustic Information for Cochlear Implant Users with Hearing Aids in Contralateral Ear . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609Y.H. Lee, B.C. Huang, C.T.M. Choi

Effect of Transmitter and Receiver Electrodes Configurations on the Capacitive Intrabody Communication Channel from 100 kHz to 100MHz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613

Ž. Lucev Vasic, Y.M. Gao, S.H. Pun, P.U. Mak, M.I. Vai, I. Krois, M. Cifrek

Performance Analysis of Em, Svd and Svm Classifiers in Classification of Carcinogenic Regions of Medical Images . . . . . . . . . . . . . . . . . . 617B. Vinoth kumar, R. Harikumar

Fluctuation of Heart Rate in Neonates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 621M. Mizote, M. Kume

Eye Torsion Determination Using Optical Flow . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625W. Krzok, U. Schönfeld

Microwave Ablation System Design to Study the Effects of Coaxial Antenna on In-Vitro Animal Tissue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629M. Chaichanyut, P. Lertprasert, S. Tungjitkusolmun

The Modeling Techniques for Analyses of Electromagnetic Distributions and Reflection Coefficients for Microwave Ablation . . . . . . . . . . . . 633M. Chaichanyut, P. Lertprasert, S. Tungjitkusolmun

Synchronized Medical Image Viewer for Remote Consultation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 637P.M. Karunaratne, D.P.N. Jayasuriya, M.B.R.D. Karunaratne, H.H.R. Karunasekera, Nuwan D. Nanayakkara

Principles of Design, Implementation and Testing of External Pacemakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641T. Klinkovsky, Marek Penhaker

A Volume-Preserving Free-Form Deformation Technique for Customising a Face Model to Another Configuration . . . . . . . . . . . . . . . . . . . . 645T. Wu, K. Mithraratne

Development of a Stand-Aone Physiological Monitoring System for Noncontact Heart and Respiration Rate Measurements on Real-TimeLinux Platform . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 649

Guanghao Sun, Shinji Gotoh, Takemi Matsui

Chaotic Analysis of Epileptic EEG Signals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652N. Kannathal, Johnny Chee, Kenneth Er, Karen Lim, Ong Hian Tat

XXVIII Table of Contents

Channel Modeling and Simulation for Galvanic Coupling Intra-body Communication . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655Y.M. Gao, X.X. Li, Ž. Lucev Vasic, S.H. Pun, P.U. Mak, I. Krois, M. Cifrek, M.I. Vai

Pacemaker Battery State Checking by Stimulation Pulse Width Detection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659M. Gála, I. Vajdikova, B. Babusiak, Marek Penhaker, M. Cerny, M. Augustynek

Indirect-Contact Surface Electrocardiography Measurements by Capacitive Electrodes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 663B. Babusiak, M. Gála, Marek Penhaker, Marek Cerny, J. Kraus

Discrimination of Parkinsonian Tremor from Essential Tremor Using the Nonlinear Analysis of Wrist Muscle EMG Signals . . . . . . . . . . . . . . 667P. Tavakkoli, H.R. Kobravi, A. Shoeibi, N. Zakhirehdari

Comparative Study of Water-Logged Meat and Fresh Meat Using Micro-CT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 671A.D. Atrisandi, S.Z. Ramdhani, E. Arianto, N.B. Wicaksono, T.L.R. Mengko, F.D.E. Latief

Evaluation of Electrohysterogram Feature Extraction to Classify the Preterm and Term Delivery Groups . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675Soo Young Sim, HoSuk Ryou, HanByul Kim, JungMin Han, Kwang Suk Park

Diaphysis Fracture on Tibia and Fibula Detection Based on Digital Image Processing and Scan Line Algorithm . . . . . . . . . . . . . . . . . . . . . . 679Yunendah Nur Fuadah, Achmad Rizal, Yuli Sun Hariyani

Brain Behavior in Learning and Memory Recall Process: A High-Resolution EEG Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683Hafeez Ullah Amin, Aamir Saeed Malik, Nasreen Badruddin, Weng-Tink Chooi

Detection of Insomnia from EEG and ECG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687H. Abdullah, T. Penzel, D. Cvetkovic

Diffusion Tensor Based Alzheimer Image Analysis Using Region Specific Volume Features and Random Forest Classifier . . . . . . . . . . . . . 691Ranjan Piyush, S. Ramakrishnan

Electrophysiological Signals Segmentation for EEG Frequency Bands and Heart Rate Variability Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . 695H. Abdullah, D. Cvetkovic

Poster Presentation – Biomaterials and Tissue Engineering

Synthesis and Characterization of Novel Self-assembly and Ph-Sensitive Anticancer Drug Carriers: (PAMAM-AP)-Modified PEG Loadingwith DOX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 699

K.C. Chang, P.S. Wu, J.M. Yeh, M.F. Hsieh

The Biomechanic Quality of Dura Mater Correlating Histology 3D-Findings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 703J. Hemza

A Continuous Model for the Embedment of Osteocytes in Bone Matrix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 707P.R. Buenzli

Enhancement of the Cytotoxic Effects of Bleomycin with Permeabilization of the Plasma Membrane by Photofrin�-MediatedPhotodynamic Therapy In Vitro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 711

Daisuke Nishikiori, Yuichi Miyamoto

Frictional Properties of Polyvinyl Alcohol Hydrogel Mixed with Water as an Artificial Articular Cartilage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714Koji Morimoto, Yoshihiro Kimura, Noriyasu Hirokawa, Tadashi Shibue, Takashi Hayami

A Preliminary Experimental Study on the Sound Generation by Flow Impingement in Branching Airway . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718G.P. Saputra, K. Nozaki, S. Ii, Shigeo Wada

Development and Characterization of Bioceramic/Polymer Composite Scaffold with Drug Release Function for Bone TissueEngineering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722

Mitsugu Todo, N. Yamada, T. Arahira, Y. Ayukawa, K. Koyano

The Effect of Microwave Treatment on the Drug Release Property of Gelatin Microspheres . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 726Kuo Feng Chou, Han Sheng Chiu, Jia Hui Lin, Wan Yu Huang, Pei Yong Chen, Wei Lin Xiao, Ting Kai Chen, Li Wen Wang

Table of Contents XXIX

Poster Presentation – Biomechanics and Computational Bioengineering

Evaluation of Lower Limb Function of Age Change by Using Principal Component Estimation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730Yohei Nomoto, Yuya Onishi, Tetuya Ohya, Kei Sawai, Hironori Koyama, Masashi Kawasumi

Influence of the Bulging Sinus Size of the Eptfe Valve Conduit on the Flow and Opening Area of the Valve Conduit . . . . . . . . . . . . . . . . . . . 734K. Okuyama, T. Akutsu

Hemodynamic Analysis of Intracranial Aneurysms with Atherosclerosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 738S. Sugiyama, K. Funamoto, T. Nakayama, K. Niizuma, T. Tominaga

Orientation and Deformation of HAp Crystals and Elastic Modulus of Single Trabecula in Bovine Femur . . . . . . . . . . . . . . . . . . . . . . . . . . . . 741S. Yamada, S. Fukuda, Shigeru Tadano

Age-Related Residual Stresses at Diaphyseal Surface of Bovine Femur Measured by XRD-IP System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743M. Onuma, S. Yamada, Shigeru Tadano

Fractal Dimension of Self-assembled 50 bp Poly(dA)•Poly(dT) DNA on HOPG Surface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745R. Nii, H. Takeuchi, K. Doi, S. Kawano

A Study on Lower Limb Joint Angles and Muscle Activities during Maximal & Sub-maximal Pedaling by Saddle Heights . . . . . . . . . . . . . . . 748J.H. Bae, J.S. Choi, D.W. Kang, Y.H. Shin, J.H. Lee, G.R. Tack

Normative Walking Spatio-Temporal Parameters of Malaysian Aged 19-24 Year Old – Initial Findings Utilizing Wearable InsoleSystem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 752

Chong Yu Zheng, Jasmy Yunus

An in Vitro Stretch-Injury Model for Elongation-controlled Neuronal Cells: Effect of Strains Along Neurite . . . . . . . . . . . . . . . . . . . . . . . . . . . 756H. Nakadate, S. Aomura, A. Kakuta

Morphological Analysis of Mouse Pulmonary Acini Extracted from Synchrotron Micro-CT Images with a Multiscale-Based SegmentationAlgorithm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 760

Luosha Xiao, Toshihiro Sera, Kenichiro Koshiyama, Shigeo Wada

Particle Swarm-Based Vertebrae Spine Modelling for Steering Vibration Impact Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 763Siti Fauziah Toha

Evolutionary Low Frequency Steering Vibration Control towards Human Spine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767Siti Fauziah Toha

Evaluation of Blood Velocity Waveform Features in Common Carotid Artery for Healthy Subjects and Cardiovascular Patients . . . . . . . . . . 771M. Saleh, A. Azhim, H. Zulaika, P. Bagherpour, Y. Kinouchi, F. Ibrahim

Foot Loading in Diabetic Patients with the Fifth Toe Deformity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 775J.B. Ma, J.S. Li, Y.D. Gu

The Kinematic Characteristic Study on Pupils Walk with Heelys . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 778Q.E. Qiu, X.F. Feng, Y.D. Gu

Bitter Taste Mediated Calcium Signaling in Enteroendocrine Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781Z. Wang, E. Walker, Vinod Suresh, J. Ingram

An Efficient Partial Shape Matching Algorithm for 3D Tooth Recognition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785Z. Zhang, X. Zhong, Sim Heng Ong, K.W.C. Foong

Effect of Exercise Intervention and Foot Load Changes on Foot Arch Evaluation Using Foot Pressure Distribution Data . . . . . . . . . . . . . . . 789K. Imaizumi, Y. Iwakami, K. Yamashita

A Constitutive Model for the Rheological Behavior of Sheep Rumen Digesta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793H. Liley, G. Molano, Y. Hemar, D. Pacheco, Vinod Suresh

XXX Table of Contents

Review on Simulation and Evaluation of Intravascular Prosthetic Device Using Finite element Method and Computational Fluid Dynamicsand Application to Simulate Aneurysm Formation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797

Vaibhavi A. Sonetha, Jayesh R. Bellare

Detect Negative Event for Depression Tendency from Web Blogs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 801Chia-Ming Tung, Wen-Hsiang Lu

Investigation of Mechanical Load on Proximal Left Anterior Descending of Coronary Artery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 805Tadashi Yamamoto, Kiyotaka Iwasaki, Jun Arai, Katsumi Ohori, Mitsuo Umezu

Poster Presentation – Biomedical Devices and Biomedical Instrumentation

Development of Pneumatic Wheeze Generator for Analysis of Wheeze in Biomedical Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809Ravichandran Subbaraman, Shirlynn Ng Wan Ern, Hamsan Muthayya, Javiel Ng Jun Wen, Favian Ng Chuan Fang, Shanshan Lin,Then Tze Kang

On the Optimization of Cutting Parameters for the Manufacture of Metallic Femoral Heads . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 813M.S. Uddin

Development of a Non-invasive System to Estimate Ankle Brachial Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817X.J.A. Tan, K.P. Chua, J.Y.A. Foo

Changes in the Water Content of the Corneal Layer of Newborn Infants Using a Corneometer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 821K. Shirai, Y. Yamamoto

Construction of Skin Impedance Model for Evaluation of Skin Barrier Functions in Case Wet-Type Electrode . . . . . . . . . . . . . . . . . . . . . . . . 825Y. Yamamoto, K. Shirai, T. Kusuhara, T. Nakamura

System Improvements for Exhaled Breath Measurement System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 828S. Kanou, S. Iitsuka, T. Nagaoka, N. Kobayashi, M. Kurahashi, S. Takeda, T. Aoki, C. Tsuji, T. Urano, T. Abe, Kazushige Magatani

A Systemic Approach to Peripheral Temperature Monitoring & Its Biomedical Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831Dhruv Mohan, Lalith Nag Sharan, Richeek Dey, Goutam Thakur

A Novel Surgeon-Assistant Device Applicable for Pedicle Detecting in Open Spine Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834R. Moradihaghighat, M. Rostami, M.A. Ghasemi

The Simple Setting of Microfluidic System with Microelectrophoresis Setup for Surface Charge Measurement . . . . . . . . . . . . . . . . . . . . . . . 838B.Y. Teoh, Y.T. Khok, P.F. Lee

Pressure Dominated PTT Calculation and Its Relation with BP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 842Li Yibin, Gao Yangyu, Li Shenlong, Li Hongyang, Zhang Yang, Deng Ning

Label-Free Detection of Meca-Mediated Methicillin-Resistant Staphylococcus Aureus (MRSA) Using Surface Plasmon ResonanceSpectroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845

K. Nawattanapaiboon, W. Kiatpathomchai, P. Santanirund, A. Wongsakulyanon, B. Sutapun, Toemsak Srikhirin

Infusion Technology - Risk Analysis from the Perspective of Biomedical Engineering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849J. Cihak, M. Augustynek, Marek Penhaker

Design, Fabrication, Experimental Study, and Test Electrochemical Detector with EWOD for Chemical Analysis . . . . . . . . . . . . . . . . . . . . . . 853K. Ugsornrat, T. Maturos, T. Pogfai, Adisorn Tuantranont

Design Sensor Chip for Repelling the Non-specific Binding for Its Application in Biomedical Sensor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857Thidarat Wangkam, Toemsak Srikhirin

Cardiac Output Measurement Using Ballistocardiogram . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 861Bharath Kurumaddali, Ganesan Marimuthu, S. Mayur Venkatesh, Rohit Suresh, B.S. Syam, Vyshak Suresh

Development and Characterization of CNT/Biopolymer Electrodes for Bio-fuel Cell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865Mitsugu Todo, K. Yamauchi, T. Arahira

Table of Contents XXXI

Microfluidic Device for Monitoring and Evaluation of Intracellular Mechanostress Responses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868Y. Nakashima, Y. Yang, K. Minami

Polymer Microneedle Array Integrated with CNT Nanofilter for Selective Drug Delivery Review Decision . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872Hao Wang, Zhuolin Xiang, Chih-Fan Hu, Aakanksha Pant, Weileun Fang, Giorgia Pastorin, Chengkuo Lee

Attachment Design of an Automatic Thrombus Monitoring System Using Multiple Optical Emitters and Detectors for an ExtracorporealPulsatile Artificial Heart . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876

S. Tsujimura, Y. Sankai

Radiofrequency Instrument for Office Hysteroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880J. Grepl, Marek Penhaker

Preliminary Study for Developed Foot Plantar Surface Temperature Monitoring System by Reducing Pressure Effect . . . . . . . . . . . . . . . . . 884HoSuk Ryou, Soo Young Sim, HanByul Kim, J.M. Han, Kwang Suk Park

High Resolution Auditory Brainstem Response System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 888Arlyana Ramli, Rumaisa Abu Hasan, N. Izayu A. Rahman, Sh-Hussain Salleh, Arief R. Harris

A Reliable Handwash Detector for Automated Hand Hygiene Documentation and Reminder System in Hospitals . . . . . . . . . . . . . . . . . . . . . 892S. Mohamed Rabeek, Andrew Norman, Minkyu Je, M. Kumarasamy Raja, Ruey Feng Peh, Michael K. Dempsey

Melamine in Milk with Surface Enhanced Raman Spectroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896A.R.M. Radzol, Khuan Y. Lee, W. Mansor, F.S. Julius

A Visual Basic Model for ISFET Sensitive to Histamine Ion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 900S.F. Mohammed Esa, Khuan Y. Lee, R. Jarmin, M. Yakup

PC Based Wireless Vital Sign Monitor Using Zigbee Communication . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 904A.R. Fikar, A. Rahman, Achmad Rizal, S. Hadiyoso, Jondri

Engineering Design and Manufacturing of Custom Craniofacial Implants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908M. Arango-Ospina, C.J. Cortés-Rodriguez

Poster Presentation – Biomedical Robotics and Surgical Technology

Analysis of Scalp Electroencephalogram Used in BCI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912Minoru Kuroiwa, Kazushige Magatani

A Study on the Closed Loop Robot Arm Control System Using SEMG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916Yuma Hiramatsu, Kazushige Magatani

Long-Range Correlations of Stride Time, Stride Length and Stride Velocity during Feedback-Controlled Treadmill Walking . . . . . . . . . . . . . 920J.S. Choi, D.W. Kang, J.H. Bae, Y.H. Shin, J.H. Lee, G.R. Tack

A Study of the Influence Which MP3 Formatted Sound Gives EEG of the Human . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 924Daiki Yamaguchi, Mutsumi Kiyozaki, Kazushige Magatani

Research of Operation Method of Accessibility Equipment for Severely Handicapped Based on Voluntary Eye Blink . . . . . . . . . . . . . . . . . . 928Tetsuya Ohya, Yohei Nomoto, Hironori Koyama, Masashi Kawasumi

Study of Touch Display in Surrounding Environmental Information Acquisition System for Deaf-blind Persons . . . . . . . . . . . . . . . . . . . . . . . . 930Yoji Naganuma, Yuya Onishi, Tetsuya Ohya, Hironori Koyama, Masashi Kawasumi

A Fundamental Study on an Input Operation of the Communication Aids by Eyeblink Using Image Analysis Methods - Change of theFeature of an Eyeblink Waveforms Resulting from Attributed to Conscious Actions Accompanying Voluntary Eyeblink - . . . . . . . . . . . . . . . . 932

Yuya Onishi, Tetsuya Ohya, Yohei Nomoto, Masashi Kawasumi

Development of Biofeedback Equipment for Toes Weight-Bearing Exercise in a Standing Position . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 936Ayako Hisari, Masaki Sekine, Masaki Yoshida

XXXII Table of Contents

Poster Presentation – Neuroengineering and Rehabilitation Engineering

Preliminary Experiment with the Influence of Sound Distraction on a Vigilance Test . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 940C. Lassfolk, M. Linnavuo, S. Talvitie, M. Hietanen, R. Sepponen

The Subliminal Vibration Stimulus Makes the Improvement of the Standing Balance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 944Masaki Yoshida, Y. Kawashima

Analysis of Brain Activity while Performing Cognitive Actions to Control a Car . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 947H. Nisar, Q.W. Yeoh, H.C. Balasubramanium, W.T. Wei, Aamir Saeed Malik

Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 951

Keyword Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 959