ILAPRAZOLE

The stomach functions to store, dissolve, and partial breakdown macromolecules. The glands of the stomach secrete a strong acid, hydrochloric acid (HCl), and protein-digesting enzymes. The stomach acid also serves to kill bacteria entering the organ.

GASTRIC PARIETAL CELL

The majority of stomach

parietal cells reside in the

corpus. Parietal cells secrete

HCl in response to gastrin from

G cells, histamine from ECL

cells, or acetylcholine (ACh)

from the vagus nerve. It can

also be stimulated by protein

ingestion, distension of the

stomach, or even the thought of

food.

Gastric Acid ( Hcl ) associated

disorders and disease

Acid-related Diseases

Acid-related diseases involve a variety of disorders that can affect the esophagus, stomach and duodenum.

DYSPEPSIA

GERD

Peptic Ulcer Disease

Duodenal Ulcers

Gastric Ulcers & NSAID-induced

Mucosal Injury

Helicobacter pylori & NSAID Use

Stress-related Mucosal Disease

Omeprazole

Lansoprazole

Pantoprazole

Esomeprazole

Rabeprazole

Dexlansoprazole

Ilaprazole

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REFERENCES:-1. http://www.medscape.com/viewarticle/705418_52. http://www.ncbi.nlm.nih.gov/pubmed/154962153. http://refluxdefense.com/images/Pathology-Low-Acid-Level-Diseases.gif4. http://www.google.co.in/imgres?imgurl=http://refluxdefense.com/images/Pathology-Low-Acid-Level-Diseases.gif&imgrefurl=http://refluxdefense.com/heartburn_GERD_articles/side-effects-antacids-and-acid-blockers.html&h=662&w=666&tbnid=7pEcZyPxb2e_YM:&zoom=1&docid=k2206-TU18oVmM&ei=oElDVebYEuGsmAW24oH4Bg&tbm=isch&client=firefox-a&ved=0CBwQMygAMAA5.http://pathology2.jhu.edu/beweb/images/ppi.gif6. http://www.refluxy.com/proton-pump-inhibitors.html7. http://www.iosrjournals.org/iosr-jdms/papers/Vol13-issue1/Version-7/D013170712.pdf8. www.cimsasia.com/India/drug/info/