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SCIENCE ---- VOI. 90 No. 2329 FRIDAY, AUGUST 18, 1939 SINGLE COPIES, .15 Here's why he prefers a B&L WIDE FIELD BlNOCULAR MICROSCOPE The B&L Wide Field Binocular Microscope is adaptable, through its rugged construction, for use in the laboratory, shop and in the field. In range of magnification, 7x to 15 Ox, it fills the gap between the hand magnifier and the standard laboratory microscope. The unusually long working distance leaves ample room for manipula- tion. Paired obj2ctives, mounted in a patented Drum Nosepiece, per- mit rapid change of magnification without refocusing. Write for complete description to Bausch & Lomb Optical Co., 642 St. Paul St., Rochester, New York. CHECK THESE 6 FEATURES: 1-Extremely Wide Field 2-Long Working Dis- tance 8-High Eye Point i-Stereoscopic Vision 5-Image erect and unreversed 6-Objectives rotate in vertical plane on B&L Patented Drum Nosepiece BAUSCH LOMB FOR YOUR EYES, INSIST ON BAUSCH & LOMB EYEWEAR, MADE FROM BAUSCH LOMB GLASS TO BAUSCH & LOMB HIGH STANDARDS OF PRECISION .a a ..... Entered as second-class matter July 18, 1928, at the Po8t Office at Lancaster, Pa., under the Act of March 3, 1879.

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Page 1: SCIENCEscience.sciencemag.org/content/sci/90/2329/local/front-matter.pdfIMPROVED base sledgeMIRT E This microtome combines utmost rigidity with greatest precision, guaranteeing absolute

SCIENCE----VOI. 90 No. 2329 FRIDAY, AUGUST 18, 1939 SINGLE COPIES, .15

Here's why he prefers a

B&L WIDE FIELD BlNOCULAR MICROSCOPEThe B&L Wide Field Binocular Microscope is adaptable, through itsrugged construction, for use in the laboratory, shop and in the field.In range of magnification, 7x to 15 Ox, it fills the gap between the handmagnifier and the standard laboratory microscope.

The unusually long working distance leaves ample room for manipula-tion. Paired obj2ctives, mounted in a patented Drum Nosepiece, per-mit rapid change of magnification without refocusing. Write forcomplete description to Bausch & Lomb Optical Co., 642 St. Paul St.,Rochester, New York.

CHECK THESE 6FEATURES:

1-Extremely WideField

2-Long Working Dis-tance

8-High Eye Pointi-Stereoscopic Vision5-Image erect and

unreversed6-Objectives rotate in

vertical plane onB&L PatentedDrum Nosepiece

BAUSCH LOMBFOR YOUR EYES, INSIST ON BAUSCH & LOMB EYEWEAR, MADE FROM BAUSCH LOMBGLASS TO BAUSCH & LOMB HIGH STANDARDS OF PRECISION .a a .....

Entered as second-class matter July 18, 1928, at the Po8t Office at Lancaster, Pa., under the Act of March 3, 1879.

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2 CEC-DETSMNT o.9,N.22

ByF. L. Meredith, M.D.

Professor of Hygiene, Tufts College

Hygiene Edition

This book meets the requirements of a threehour full year college course. Its aim is toteach students the principles upon which to con-

duct their daily lives. Chapters on Health Main-tenance, Anatomy, Physiology and PathologicalConditions are given first, thus providing a

foundation upon which to build a sound course

in Hygiene and Mental Hygiene.230 Illus. 802 Pages. $3.50

Teachers Comment: "The book is so complete,so scientific in its presentation of the subject,yet so generous in its attitudes toward life"

Twelve Hours of HygieneThis short textbook is written for the one-se-

mester college freshman course in which theclass meets once a week. It presents a survey

of personal hygiene which is thought provoking,interesting and inspirational. It is scientificallyand pedagogically sound.

110 Illus. 387 Pages. $1.90

Teachers Comment: "It is concise but not am-

biguous. It is amply illustrated with drawingsthat aid in creating a clear and scientific under-standing of the subject"

Both books are widely used as classroom texts in colleges and universities throughout the United States.

THE BLAKISTON COMPANY PHILADELPHIA

An Advance inSINK MATERIAL

of Great Importance toChemical Education* Molded in one piece fromcarbon-impregnated ma-terial.

* Free from distortion-inert to solvents.

Hard-dense-vIrtuallynon-absorbent.

* lVill not crack or breakunder ordinary weightsor thermal shocks. Karcite Sink

* Do not chip easily, re- No. S-675sist abrasion-Lighter,Stronger, Easier to Clean.

gec4 KARCITEMOLDED CERAMIC SINKS

Karcite Sinks have a ceramic body of fine uniform texture, thepores of which are filled with carbon. Color-gray black. Smoothsurface with dull gloss finish. 39 designs now available from stock.Distributed by most leading manufacturers of laboratory furniture.Be sure to specify Karcite Sinks on all orders. Write for Catalogand Price List.

CERAMICS ;DIVISION LABORATORY FURNffURE ERTS

C. G. CAMPBELL, PRES. AND GEN. MGR.301 Lincoln St., Kewaunee, Wis.

Eastern Branch: 220 E. 42nd St., New York, N. Y.Mid-West Office: 1208 Madison St., Evanston, Ill.

Representatives in Principal Cities

Review of the History and Philosophyof Science and of the History of

Learning and Culture,edited by

GEORGE SARTON, D.Sc.HARVARD LIBRARY 185, Cambridge, Mass.

Isis may be obtained from any Bookseller at theprice of 6 dollars per volume illustrated. Membersof the History of Science Society receive each yearat least one volume of about 600 pp. free of charge.Annual dues, 5 dollars. Corresponding Secretary,Dr. Henry R. Viets, 8 The Fenway, Boston, Mass.

Isis is the foremost journal on the history ofscience published in the world to-day. It containsarticles, reviews, notes, queries, and elaborate criti-cal bibliographies of the history and philosophy ofscience. Vols. 30 and 31 will be published in 1939.

Writers of books and papers on the history ofscience are asked to send a copy as promptly aspossible to the Editor of Isis in order that theymay be registered in the Critical bibliography.This is the best way of obtaining for their workits certain incorporation into the literature of thesubject.

Isis may be examined in any good referencelibrary all over the world.

ST. CATHERINE PRESS, BRUGES, BELGIUM

SCIENCE-ADVERTISEMENTS 0VOL. 901 No. 23292

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AUGUST 18, 1939 SCIENCE-ADVERTISEMENTS 3

The Spencer

DRIGHT-LINEHAEMACYTOMETER

-for greater ease and accuracy in countingAll who make blood counts shouldexperience the greater ease andtake advantage of the increasedaccuracy attained through usingthe Spencer "Bright-Line" Haema-cytometer.It has bright lines on a dark back-ground instead of gray lines on alight background.This is accomplished by fusing intothe glass counting chamber a rho-dium surface in which the linesare cut.

The important advantages of thisconstruction are:(1) Increased v i s i b i l i t y of both

blood corpuscles and lines. (Itis not necessary to stop downthe microscope condenser forcomfortable observation.)

(2) Approximately 16% more evendistribution of corpuscles (be-cause of the metal surface.)

To fully appreciate the real supe-riority of the "Bright-Line", youmust see it under the microscope.

Write Dept. V2 for a demonstration and descriptive literature

Spencer Lens CompanyMICROSCOPESMICROTOMESPHOTOMICROGRAPHICEQUIPMENT

REFRACTOMETERSCOLORIMETERSSPECTROMETERSPROJECTORS

AUGUST 18, 1939 SCIENCE-ADVERTISEMENTS 3

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4 SCIRNCE-ADVERTISEMENTS

w

IMPROVED base sledgeMIRT EThis microtome combines utmost rigidity with greatestprecision, guaranteeing absolute evenness and accuracyin cutting.

Automatic fee,-ling mechanism is completely protected fromdirt and falling sections. Due to its extreme rigidity themicrotome is well suited for cuffing hard objects such aswood or bone. Thickness of section is adjustable between1 and 20 microns. Objects can be cut from paraffin, cel-lodion or frozen sections. The large Christeller freezingstage (9 x 13 cm) i's particularly well suited for frozen sec-tions of unusually large dimensions.

Special freezing microtomes, Minot microtomes for rapidserial sectioning, and various sledge microtomes are avail-able in a wide price range for all sectioning purposes.

Write for Catalog No. 16-A U-18

and 45 page manual on "The Use of the Microtome" whichexplains embedding, cuffing and staining technique.

VOL. 90, NO. 23294 SCIPNCE-ADVERTISEMENTS

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AUUT1,13 CENEAVRIEET

Now Available

GLUTAMINE(NH2 * CO * CH * NH2 * CH2 * CH2 - COOH)

This compound is of unusual interest tothe bacteriologist following the discoveryof its role as an essential in the nutri-tion of streptococcus haemolyticus (1) (2).

General Biochemicals Glutamine is avail-able as crystals, prepared from naturalsources. To facilitate research in bacterialnutrition, this essential organic com-pound is offered to research workers atspecial prices.A list of biochemical products used invitamin research available for scientificinvestigators will be sent upon request.

(1) McIlwain et al, Biochem. J., 33:223 (1939)"Glutamine and the Growth of Strepto-coccus Haemolyticus."

(2) M. Landy, General Biochemicals, Inc.(To be published)

GENERAL BIOCHEMICALS, INC.(Division ofJohn WyetA & Brother, Incorporated)

418-J REPUBLIC BUILDING * CLEVELAND, OHIO

I

ilI LI

AUGUST 18, 1939 SCIENCE-ADVERTISEMENTS 5

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6 SCIENCE-ADVERTISEMENTS 90, No. 2329

APPARATUSfor EXACTING SERVICE in

Physiology and other branches ofExcperinental Biology

Kymographs Recording Levers

Time Recorders Manometers

Electrodes Operating Holders

Keys and Switches Stands and Clamps

Tambours Inductorium

Magnetic'Signals Respiration Pump

Parts and Accessories

Simple in design-carefully finished-of moderate price

Write for the illustrated and descriptive catalogue

The HARVARD APPARATUS COMPANY, Incorporated

Dover, Massachusetts

(Organized on a non-profit basis for the advancement of teaching and investigation in physiologry and the allied sciences)

I:11

SCIENCE-ADVERTISEMENTS VOL. 90, NO. 23296

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AuGUST 18, 1939

ican Soeiety of Mechanical Engineers, serving for twoterms; three times a vice-president of the American Asso-ciation for the Advancement of Science, and a member ofthe American Society of Civil Engineers and of numerousother technical and academic organizations in this countryand abroad. He also served on several important stateand federal commissions.

Dr. Thurston was considered an authority on materialsof construction, steam engines and boilers, and the historyof engineering, as well as on the philosophy of education.His most widely known work, "A History of the Growthof the Steam Engine," published originally in 1878, isscheduled for republication this year as part of the cele-bration of the eentennial of his birth.

Training engineers to meet the problems of the futurewas a subject of perennial interest to Dr. Thurston and.will be the theme of the Anniversary Convocation.Thurston, the pioneer, proclaimed values and enunciatedprinciples that have a bearing to-day, and the spirit ofThurston counsels boldness in grasping the immense oppor-tunities of to-morrow.

RECENT DEATHS AND MEMORIALSDR. LEWIS D. ROBERTS, professor of physical chem-

istry at the University of Southern California, died bysuicide on August 3. He was in his fifty-sixth year.

DR. CLYDE MASON SHAW, professor emeritus of theCollege of Pharmacy at the University of Illinois,Chicago, died on August 5, at the age of seventy-oneyears.

DR. COOPER CURTICE, who retired as veternarian atthe Bureau of Animal Industry of the U. S. Depart-ment of Agriculture in 1930, known for his work in theeradication of cattle ticks and cattle-tick fever, diedon August 8, at the age of eighty-three years.

Nature reports the death on July 28 of ProfessorR. W. Reid, emeritus regius professor of anatomy inthe University of Aberdeen; and of Scoresby Rout-ledge, known for his investigations among the Akikuyuof East Africa and of the archeology and ethnologyof Easter Island, on July 31, in his eightieth year.

ACCORDING to Nature a teak memorial seat to the lateSir William Perkin, the chemist, is to be unveiled anddedicated to the public at Sudbury, Middlesex, onAugust 12. The memorial will be outside a recreationground, and opposite the site where Sir William'shouse and laboratory stood. The cost of the memorialhas been met by public subscription.

SCIENTIFIC NOTES AND NEWSDR. ROBERT A. MILIKA.N, of the California Insti-

tute of Technology, accompanied by Dr. H. VictorNeher and Dr. W. H. Pickering, sailed for Australiaon August 16. They will engage in cosmic ray re-

search in Australia, Tasmania, the East Indies, Indiaand Egypt, returning in February, 1940.

THE Royal College of Physicians has made the fol-lowing awards: the Baly Gold Medal to Dr. C. H.Best, professor of physiology in the University ofToronto, for his physiological researches; the MoxonGold Medal to Sir Arthur Hurst, senior physician toGuy's Hospital, for his researches and observations inclinical medicine; the Weber-Parkes Medal and Prizeto Sir Pendrill Varrier-Jones, founder and medicaldirector of the Papworth Village Settlement, for hiswork on tuberculosis.

THE gold medal of the Royal Agricultural Societyof England has been awarded to Sir George Stapledon,professor of agricultural botany at the University Col-lege of Wales at Aberystwyth and director of theWelsh Plant Breeding Station, "for his distinguishedservices to agriculture."Tim prize of the Senckenberg Foundation of the

value of about 4,000 marks, which was established ahundred and seventy-five years ago, was awarded on

the occasion of the twenty-fifth anniversary of theuniversity at Frankfurt-a/M, to Dr. Ernst Ruskafor his-work with the electron mieroscope. The prize

is awarded every three years to a German investigatorfor contributions to the advancement of medicine orscience.THE Journal of the American Medical Association

reports that at the annual meeting of the MinnesotaState Medical Association it was voted to present thedistinguished service medal and scroll, awarded tomembers for special contributions to the work of theassociation, to the late Drs. William J. Mayo andCharles H. Mayo. Their photographs will be hung inthe Medical School of the University of Minnesota.

DR. GEORGE H. FANCHER, professor of petroleumengineering at the University of Texas, has been electeda fellow of the International Institute of Petroleum,which has its headquarters in London.THE University of Edinburgh has conferred the

doctorate of laws on Dr. Francis H. A. Marshall, fellowof Christ's College, Cambridge, and reader in agricul-tural physiology in the University of Cambridge, inrecognition of his work in the physiology of repro.duction.PROFESSOR LuIGo D'AMATo, director of the Medical

Clinic of the University of Naples, has been made asenator of Italy.

DR. LAIGNEL-LAVASTINE, professor of the history ofmedicine at the University of Paris, has been electedpresident of the International Society of the Historyof Medicine.

SCIENCE 153

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VOL. 90, No. 2329

clearance was studied in a series of tubes in which thedistance between the walls was varied from 1.3 mm to22.0 mm. The gas separation (ratio of ammonia tomethane) rose sharply with increasing wall clearanceto a rather broad maximum at 7 mm. The effect ofgas pressure was investigated from 11 to 60 cm of Hgfor the different tubes. The 7 mm tube gave a maxi-mum gas separation of 27 per cent. at 20 cm pressure.The pressure however is not critical nor is the optimumpressure the same for all gas mixtures. In these teststhe temperature difference between the walls was 3500and the average temperature of the gas close to 150°.By varying the power input it was found that the finalgas separation increased with the temperature differ-ence between the walls. The rate of separation wasinvestigated for a wall clearance of 7 mm and a tem-perature difference of 3500. The separation rose to 90per cent. of its final value in 15 minutes. The absoluterate at which gas could be removed without decreasingthe separation factor was not determined with ac-curacy; it was observed, however, that I cc of gas(N. T. P.) could be removed every 15 minutes withoutinfluencing the percentage separation. This speed sug-gests that a continuous flow method of operation shouldbe feasible.A number of gas mixtures have been studied in addi-

tion to the one mentioned above. The operation of thetube can be shown in a striking manner with a uniform50-50 mixture of helium and bromine. In the courseof a few minutes the bromine completely disappearsfrom the top of the tube and becomes concentrated atthe bottom. The separation of isotopes is easily demon-strated with HCl, in which gas the ratio of Cl35 to Cl37was changed at a pressure of 20 cm from 3.2, its normalvalue, to 2.8 in a few minutes. The optimum condi-tions of operation depend, of course, on the nature ofthe gas. The results obtained with. different gas mix-tures lead to the conclusion that the separation dependsprimarily on the difference in mass of the two com-ponents divided by their sum.

Experiments have been performed which throw addi-tional light on the mechanism of operation. When theentire tube was inclined 13° from the vertical theseparation was decreased from 27 per cent. to 5 percent. In another apparatus a series of corrugationswas placed every 3 cm along the inner tube in such amanner that any gas moving along the heated wallwould be deflected into the intervening space. In a50-50 methane-ammonia mixture the average tempera-ture of the gas was reduced about 150 and the finalseparation enhanced about 4 per cent. The design ofthe tube also appears to have a marked effect on thegas separation. A tube was built along the linesdescribed by Clusius and Dickel with a heated tungstenwire extending down the center and a 7 mm clearance.After a run of several hours a smaller final separation

of the chlorine isotope was observed with an 800°difference in temperature than was obtained in 15 min-utes with the concentric glass tubes for a 3500 differ-ence in temperature. A 3500 difference in temperaturegave only a negligible separation. A similar tube witha 4 mm platinum ribbon down the center failed toshow an appreciable separation. It is evident thatseparation is augmented by symmetry of the two sur-faces. An all-glass apparatus in which the outer wallwas heated and the inner cooled gave a separationvalue only slightly lower than when the inner wall washeated; the average temperature of the gas, however,was materially higher.The rate of mixing of the separated gases has been

investigated for various tubes. The results show thatthe rate of back diffusion increases with wall clearanceand becomes very rapid for outside tubes of largerdiameter.Reviewing the above results as a whole, it is evident

that conditions involving both wall symmetry and cor-rugations enhance swirl definition and thereby enhanceseparation. On the other hand, separation is mate-rially lower in straight wire or ribbon-centered tubesas well as in tubes having small wall clearances inwhich swirls are either poorly defined or impossible.It appears that the mechanism of separation is differ-ent in the two cases. Under conditions where swirls arewell defined the separation results from the combinedaction of initial and thermal diffusion within the swirls.In wire-centered tubes or glass tubes with small wallclearances where the swirls are poorly defined, themechanism may involve thermal diffusion and anoverall convection current.We wish to thank Mr. Leonardo Testa, the glass-

blower, for constructing the large number of tubes usedin these experiments.

ARTHUR BRAMLEYA. ]KEITH BREWER

BUREAU OF CHEMISTRY AND SOILS,U. S. DEPARTMENT O0 AGRICULTURE

BOOKS RECEIVEDCONWAY, EDWARD J. Micro-diffusion Analysis and Volu.

metric Error. Pp. xiii + 306. 49 figures. Crosby,Lockwood, London. 25/-.

CUMMINGS, ALEX., CHARLES, and SNYDER A. KAY. AText-book of Quantitative Chemical Analysis. Pp.xv+496. 85 figures. Van Nostrand. $5.00.

Meeting the Needs of the Mentally Retarded. BulletinNo. 420 of the Department of Public Instruction, Com-monwealth of Pennsylvania. Pp. 158. Illustrated.The Department, Harrisburg.

MILLS, CLARENCE A. Medical Climatology. Pp. vii +296. Illustrated. Charles C Thomas. $4.50.

POPE, CLIFFORD H. Turtles of the United States andCanada. Pp. xviii + 342 + v. 99 plates. Knopf.$3.75.

WOLF, RALPH F. India Rubber Man; The Story ofCharles Goodyear. Pp. 291. Illustrated. CaxtonPrinters, Caldwell, Idaho. $3.00.

166 SCIENCE

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AUGUST 18, 1939 SCIENCE-ADVERTISEMENTS

Praise for an Outstanding New Text

Fundamental Principlesof

BacteriologyBy A. J. SALLE

University of California

659 pages, 6 x 9, illustrated. $4.00EACHERS have acclaimed this newly published text as one of the most important contributions to thefield of bacteriology that has appeared in recent years.

The following comments are representative:

"I have examined it with considerable interest because of its completeness as a book in general bacteriology.I would like to congratulate Dr. Salle and you on what I consider to be the best textbook that has ever beenpublished on that subject." Professor GEORGE M. LAWSON, University of Virginia"I feel sure that Dr. Salle's book is a distinct contribution to bacteriological texts. It is.full of meat and notthe same old material rehashed in a slightly different fashion."

Professor WILLIAM BURROWS, University of ChicagoThis combined textbook and laboratory manual lays particular stress upon fundamentals, gives explanationsof all phenomena described in the book insofar as it is possible to do so, and emphasizes the importance ofchemistry in an intelligent approach to the subject matter.

The book is intended for students who are beginning the study of bacteriology, and especially for those whoare going to specialize in the subject or in closely related fields.Special Features of the Book:

-the book is profusely Mustrated with chemical formulas because the author believes thatno student can fully understand bacteriology without first having had courses In inorganicand organic chemistry.

-the book is unique in that it is a combination textbook and laboratoryl manuaL The ex-perimental portion Is not added as an appendix but is woven Into the body of the text underthe appropriate chapters. Thus the textbook material goes hand in hand with systemati-cally arranged laboratory work.

-the book covers in detail the following topics, which have received inadequate treatment inmost other texts.

(a) BIOLOGICAL STAINS: A discussion of dyes and staining solutions;(b) BACTERIAL RESPIRATION: A pioneer treatment of this subject;(c) YEASTS AND MOLDS: Profusely mustrated with morphological pictures of the

various organisms;(d) ENZYMES: Detailed classification including the chemical reactions for the action

of enzymes on the specific substrates and the end products formed.-the chapter on Disinfectiou and Disinfectants Includes a detailed discussion of the toxicity

of ions toward bacteria.-the chapters on Protein Decomposition and lndustrial Fermentations also contaln consid-

erable material not ordinarily found in other textbooks.

McGRAW-HILL BOOK COMPANY, INC.330 West 42nd Street, New York, N. Y. Aldwych House, London, W.C.2

7

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AUGUST 18, 1939 SCIENCE-ADVERTISEMENTS 9

riAfPORCELAIN BASKET

~~~~FORCHEMICAL CENTRIFUGEThe new International Chemical Centrifuge, with PORCELAIN

Basket and Draining Chamber, is the answer to a persistent demand.This centrifuge is for use in those cases where smali amounts of stronglycorrosive mother liquors, which would severely attack metal parts, areinvolved and also for those cases where it is desired to avoid any possi-bility of contamination from a metal basket and draining chamber.

All of the porcelain parts are housed inside a steel casing with a lock-ing hinge cover for protection. The inner and outer surfaces of the steelcasings are protected by a baked Glyptal enamel. These porcelain partsare interchangeable with the metal baskets and draining chambers onany international Chemical Centrifuge now in use.

The motor of the International Chemical Centrifuge is of universaltype to operate on any lighting circuit, either A.C. or D.C. The basketis approximately 5 inches in diameter by 2Y2 inches deep with 8/4 inchflange and has 0.3 liter cake capacity.

Descriptive Bulletin CH upon request

INTERNATIONAL EQUIPMENT COMPANY352 Western Avenue Boston, Mass.

Makers of Fine Centrifuges

FREENEW Bulletin of

CASTLE

Bactenological ApparatusA new and important bulletin of Castle Ap-paratus for the Bacteriological Laboratory isnow ready for distribution. WRITE TO-DAY FOR YOUR COPY.This new bulletin, fully illustrated, lists thelatest Castle laboratory apparatus includingAutoclaves, -single and double wall types,laboratory sterilizers, precision incubators, par-affin embedding ovens, Arnold steam steriliz-ers, serological water baths and Hot-air steriliz-ers. Bring your file up-to-date by asking foryour copy now, and mentioning the apparatuson which you want more detailed informaition.

WILMOT CASTLE COMPANY1212 University Avenue Rochester, N. Y.

AuGuUST 18, 1939 SCIENCE-ADVERTISEMENTS 9