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Improving catheter-related infections in the I.C.U. A FRENCH WEST INDIES EXPERIENCE r. Benoît Rozé opical and infectious diseases unit tensive care unit

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Improving catheter-related infections in the I.C.U.A FRENCH WEST INDIES EXPERIENCE

Dr. Benoît Rozé

Tropical and infectious diseases unit

Intensive care unit

https://upload.wikimedia.org/wikipedia/commons/thumb/a/af/CaribbeanIslands.png/790px-CaribbeanIslands.png

La Martinique – French West Indies

great island A teaching hospitalA carribbean E.C.M.O. center

An incredible rate of catheter-related infections

� French national

surveillance system � Data from Martinique

[Pronovost. NEJM 2006]

2012 – French National Surveillance onCatheter-related bloodstream infection in ICU.

Réa CHU FDF = 4,05

High cost – ineffectiveness of catheter-related bloodstream infections

[Blot. CID. 2005]

spontaneous generation could not occur”

Louis Pasteur - 1857

Epidemiology of CRBI01-02-03/ 2013

0

2

4

6

8

10

12

14

Germes

Kp BLSE

Pseudomonas aeruginosa

Staphylococcus spp

SAMS

Acinetobacter baumani S

Candida

Proteus mirabilis

Kp sauvage

Enterococcus faecalis

ABRI

Pseudomonas totoR

Evolution de l'indicateur ICSHA

117,6

137,9

106,6

74,4

104,6

94,4

127,5

107,9

89,4

74,9

89,1

60,8

0,0

100,0

200,0

Janvier Février Mars Avril Mai Juin Juillet Août Septembre Octobre Novembre Décembre

CHU de fort de France

OBJECTIFà atteindre:

≥150%

SERVICE: RéanimationAnnée 2012

Réanimation

Classe A

Classe B

Classe C

Classe D

Classe

E

Anatomical sites of infected catheter

J2 J3 J4 J5 J6 J7 J8 J9

J10

J11

J12

J13

J14

J15

J16

J17

J18

J19

J20

Sous clavier

Jugulaire interne

Fémoral

� Weigh the risks and benefits of placing a central venous device (IA)

� Avoid using the femoral vein for central veinous access (IA)

� Evaluate the catheter insertion daily (II)

� Promptly remove any catheter that is no longer essential (IA)

� Replace the catheter within 48h when adherence to aseptic technique is not ensured (IB)

� Perform hand hygiene procedures

� Periodically assess knowledge of and adherence to guidelines for all personnel involved (IA)

In fact : the central-catheter protocol

� Weigh the risks and benefits : only 4 possibilities

� Prevent chemical irritation of the tissues (Thiopental, vancomycine)

� Catecholamine administration

� Prolonged parenteral nutrition

� Difficult peripheral intravenous access

� Selection of catheterisation site

� Maintain aseptic technique for the insertion and care of intravascularcatheters (IB)

� Replace femoral catheter within 48h

� Note skin aspect on clinical data sheet TID

� 4% chlorexidine bathing, once daily [Bleasdale. Arch Intern Med 2007]

Selection of catheterisation site

Maintain aseptic technique for the insertion

Note skin aspect

Education, Training and Staffing

40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18oc

t-12

nov-

12

déc-

12

janv

-13

févr

-13

mar

s-13

avr-

13

mai

-13

Immersion IDE/ test outils/bactériot0 (observance/incidences) t0Formations paramédicale/médicaleSurveillance/prévention

R t0 R t1 R t2 R t3Bilan à 3 mois

%observance mesures prévention %observance mesures prévention

incidence/acquisitions BLSE incidence/acquisitions BLSE

conso AB conso AB

conso SHA conso SHA

taux incidence PAVM (t0 et REA RAISIN) %observance mesures prévention

taux incidence BLC (t0 et REA RAISIN) incidence/acquisitions BLSE

taux incidence IU (t0 et REA RAISIN) conso AB

conso SHA

%observance mesures prévention

incidence/acquisitions BLSE

conso AB

conso SHA

taux incidence PAVM

taux incidence BLC

taux incidence IU

t3

Programme surveillance et prévention des IN Réanima tion polyvalente

t1 t2Formation

Better practices, better results !

Take home messages

� catheter-related bloodstream infections are expensive, prevalent

� intervention to reduce these infections is simple and inexpensive

� Coincident with our intervention, the median rate of infection decreased from 4.3 per 1000 catheter-days at baseline to 1.1 after the implementation of the intervention.

� sustainability of this benefit have to be evaluated

� this intervention could significantly reduce morbidity and the costs of care associated with catheter-related bloodstream infections