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IN Cell Analyzer Journal Citations Cancer Biology (including DNA repair) Kaumudi M. Bhawe, Robert A. Blake, Douglas O. Clary, and Peter M. Flanagan An Automated Image Capture and Quantitation Approach to Identify Proteins Affecting Tumor Cell Proliferation Journal of Biomolecular Screening 2004; April 2004 9: 216-222

Das, A., Sato, M., Story, M., Peyton, M., Graves, R., Redpath, S., Girard, L., Gazadar, A., Shay, J., Minna, J., and Nirod, C. Non–Small Cell Lung Cancers with Kinase Domain Mutations in the Epidermal Growth Factor Receptor Are Sensitive to Ionizing Radiation Cancer Research 2006; 66 9601 – 9608

Hyun-Joo Park, Emily Partridge, Pam Cheung, Judy Pawling, Rob Donovan, Jeffrey L.Wr ana, and James W.Dennis Chemical Enhancers of Cytokine Signaling that Suppress Microfilament Turnover and Tumor Cell Growth Cancer Research 2006; 66(7): 3558-66

Bin, Zhang, Xiubin, Gu, Uppalapati, Uma, Ashwell, Mark A., Leggett, David S., and Li, Chiang J. High-Content Fluorescent-Based Assay for Screening Activators of DNA Damage Checkpoint Pathways Journal of Biomolecular Screening 2008; 13 538 – 543

Katz, D., Ito, E., Lau, K. S., Mocanu, J. D., Bastianutto, C., Schimmer, A. D., and Liu, F. F. Increased efficiency for performing colony formation assays in 96-well plates: novel applications to combination therapies and high-throughput screening BioTechniques 2008; 44 S9 - S14

Prevo, R, Deutsch, E, Sampson, O, Diplexcito, J, Cengel, K, Harper, J, O'Neill, P, McKenna, W. G, Patel, S, and Bernhard, E J. Class I PI3 Kinase Inhibition by the Pyridinylfuranopyrimidine Inhibitor PI-103 Enhances Tumor Radiosensitivity Cancer Research 2008; 68 5915 – 5923

Grace K.Y. Chan, Bart A. Lutterbach, Bo-Sheng Pan, Ilona Kariv and Alexander A. Szewczak, High Throughput Analysis of HGF-Stimulated Cell Scattering, Journal of Biomolecular Screening 2008; Vol. 13, No. 9, 847-854

Anne-Marie Liberatore, Hélène Coulomb, Dominique Pons, Olivier Dutruel, Philip G. Kasprzyk, Mark Carlson, Ann Savola Nelson, Simon P. Newman, Chloe Stengel, Pierrïck Auvray, Vincent Hesry, Béatrice Foll, Nadine Narboux, Delphine Morlais, Mélissa Le Moing, Sonia Bernetiere, Raphael Dellile, Jose Camara, Eric Ferrandis, Dennis C. Bigg, and Grégoire P. Prévost IRC-083927 is a new tubulin binder that inhibits growth of human tumor cells resistant to standard tubulin-binding agents Molecular Cancer Therapeutics 2008;7(8). August 2008

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Antonis Kourtidis, Rekha Srinivasaiah, Richard D Carkner, M Julia Brosnan, and Douglas S Conklin Peroxisome proliferator-activated receptor-γ protects ERBB2-positive breast cancer cells from palmitate toxicity Breast Cancer Research 2009; 11(2): R16.

Chao Zhang, Na Yang, Chun-hao Yang, Hua-sheng Ding, Cheng Luo, Yu Zhang, Mao-jiang Wu, Xiong-wen Zhang, Xu Shen, Hua-liang Jiang, Ling-hua Meng, and Jian Ding S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mTOR Signaling and Microtubule Cytoskeleton PLoS ONE 2009; 4(3): e4881.

Helenia Ansuini, Annalisa Meola, Zeynep Gunes, Valentina Paradisi, Monica Pezzanera, Stefano Acali, Claudia Santini, Alessandra Luzzago, Federica Mori, Domenico Lazzaro, Gennaro Ciliberto, Alfredo Nicosia, Nicola La Monica, and Alessandra Vitelli Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer Journal of Oncology 2009; Volume 2009, Article ID 951917, 10 pages

John T. Norton, Steven A. Titus, Dwayne Dexter, Christopher P. Austin, Wei Zheng, Sui Huang Automated High-Content Screening for Compounds That Disassemble the Perinucleolar Compartment Journal of Biomolecular Screening 2009; Vol. 14, No. 9, 1045-1053

Hiroshi Hirai, Yoshikazu Iwasawa, Megumu Okada, Tsuyoshi Arai, Toshihide Nishibata, Makiko Kobayashi, Toshifumi Kimura, Naoki Kaneko, Junko Ohtani, Kazunori Yamanaka, Hiraku Itadani, Ikuko Takahashi-Suzuki, Kazuhiro Fukasawa, Hiroko Oki, Tadahiro Nambu, Jian Jiang, Takumi Sakai, Hiroharu Arakawa, Toshihiro Sakamoto, Takeshi Sagara, Takashi Yoshizumi, Shinji Mizuarai, and Hidehito Kotani Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents Molecular Cancer Therapeutics 2009; 8(11):2992–3000

Marta Barradas, Emma Anderton, Juan Carlos Acosta, SiDe Li, Ana Banito, Marc Rodriguez-Niedenführ, Goedele Maertens, Michaela Banck, Ming-Ming Zhou, Martin J. Walsh, Gordon Peters and Jesús Gil1, Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS Genes & Development 2009; 23: 1177-1182

Hong Zhao, M.D., Ph.D., Carol Tang, Ph.D., Kemi Cui, M.D., Ph.D.,Beng-Ti Ang, M.D., and Steph en T. C. Wong, Ph.D. A screening platform for glioma growth and invasion using bioluminescence imaging Journal of Neurosurgery 2010, 111:238–246, 2009 238 J

Antonis Kourtidis, Ritu Jain, Richard D. Carkner, Cheryl Eifert, M. Julia Brosnan, and Douglas S. Conklin An RNA Interference Screen Identifies Metabolic Regulators NR1D1 and PBP as Novel Survival Factors for Breast Cancer Cells with the ERBB2 Signature Cancer Research 2010; March 1, 2010 70:1783-1792

Geoff S. Higgins, Remko Prevo, Yin-Fai Lee, Thomas Helleday, Ruth J. Muschel, Steve Taylor, Michio Yoshimura, Ian D. Hickson, Eric J. Bernhard, and W. Gillies McKenna A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown Cancer Research 2010; May 1, 2010 70:3853

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Meuillet EJ, Zuohe S, Lemos R, Ihle N, Kingston J, Watkins R, Moses SA, Zhang S, Du-Cuny L, Herbst R, Jacoby JJ, Zhou LL, Ahad AM, Mash EA, Kirkpatrick DL, Powis G. Molecular Pharmacology and Antitumor Activity of PHT-427, a Novel Akt/Phosphatidylinositide-Dependent Protein Kinase 1 Pleckstrin Homology Domain Inhibitor Molecular Cancer Therapeutics 2010; 2010 Mar;9(3):706-17

Kraenkel N, Armstrong SP, McArdle CA, Dayan C, Madeddu P Early alterations of kinin-mediated functions of circulating pro-angiogenic cells in type I diabetes. PLoS One 2010; ePub 20.05.10. AR Beckett, S McKinney, SS Poon, J Fee, and SA Aparicio STROMAL-EPITHELIAL INTERACTIONS: Identifying stromal-epithelial interactions in the mammary gland through genome-wide siRNA screening. Cancer Research 2009; 69,S85–S85

Yuka Nakazawa, Shunichi Yamashita, Alan R. Lehmannb, and Tomoo Ogi A semi-automated non-radioactive system for measuring recovery of RNA synthesis and unscheduled DNA synthesis using ethynyluracil derivatives DNA Repair 2010; Volume 9, Issue 5, 4 May 2010, Pages 506-516

Aya Ishikawa, Motohiro Yamauchi, Keiji Suzuki, Shunichi Yamashita Image-based quantitative determination of DNA damage signal reveals a threshold for G2 checkpoint activation in response to ionizing radiation Genome Integrity 2010; 2010 Aug 4;1(1):10.

Nicolle Kränkel, Stephen Paul Armstrong, Craig Alexander McArdle, Colin Dayan, Paolo Madeddu Distinct Kinin-Induced Functions Are Altered in Circulating Cells of Young Type 1 Diabetic Patients PLoS ONE 2010; June 2010 Volume 5 Issue 6 e11146

Shilpi Arora, Irma M Gonzales, R Tanner Hagelstrom, Christian Beaudry, Ashish Choudhary, Chao Sima, Raoul Tibes, Spyro Mousses and David O Azorsa RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma Molecular Cancer 2010; 9: 218.

Christine Kaiser, Nathalie Meurice, Irma M. Gonzales, Shilpi Arora, Christian Beaudry, Kristen M. Bisanz, Alexander C. Robeson, Joachim Petit, David O. Azorsa Chemogenomic Analysis Identifies Macbecin II as a Compound Specific for SMAD4-Negative Colon Cancer Cells Chemical Biology & Drug Design 2010; Volume 75, Issue 4, pages 360–368, April 2010

Niamh Lynam-Lennon, John V. Reynolds, Graham P. Pidgeon, Joanne Lysaght, Laure Marignol, and Stephen G. Maher Alterations in DNA Repair Efficiency are Involved in the Radioresistance of Esophageal Adenocarcinoma Radiation Research 2010; 2010 Dec;174(6):703-11

V Borgdorff, M E Lleonart, C L Bishop, D Fessart, A H Bergin, M G Overhoff and D H Beach Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21Waf1/Cip1 Oncogene 2010; 29, 2262-2271 (15 April 2010)

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Kenneth W. Wood, Latesh Lad, Lusong Luo, Xiangping Qian, Steven D. Knight, Neysa Nevins, Katjusa Brejc, David Sutton, Aidan G. Gilmartin, Penelope R. Chua, Radhika Desai, Stephen P. Schauer, Dean E. McNulty, Roland S. Annan, Lisa D. Belmont, Carlos Garcia, Yan Lee, Melody A. Diamond, Leo F. Faucette, Michele Giardiniere, ShuYun Zhang, Chiu-Mei Sun, Justin D. Vidal, Serge Lichtsteiner, William D. Cornwell, Joel D. Greshock, Richard F. Wooster, Jeffrey T. Finer, Robert A. Copeland, Pearl S. Huang, David J. Morgans, Jr., Dashyant Dhanak, Gustave Bergnes, Roman Sakowicz, and Jeffrey R. Jackson Antitumor activity of an allosteric inhibitor of centromere-associated protein-E PNAS 2010; March 30, 2010 vol. 107 no. 13 5839-5844

Joel Greshock, Kurtis E. Bachman, Yan Y. Degenhardt, Junping Jing, Yuan H. Wen, Stephen Eastman, Elizabeth McNeil, Christopher Moy, Ronald Wegrzyn, Kurt Auger, Mary Ann Hardwicke, and Richard Wooster Molecular Target Class Is Predictive of In vitro Response Profile Cancer Research 2010; 70(9); 3677–86. ©2010 AACR.

Derek J. Richard, Kienan Savage, Emma Bolderson, Liza Cubeddu, Sairei So, Mihaela Ghita, David J. Chen, Malcolm F. White, Kerry Richard, Kevin M. Prise, Giuseppe Schettino and Kum Kum Khanna hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex Nucleic Acids Research 2010; Advance Access published November 3, 2010

Development of a High-Content Screening Method for Chemicals Modulating DNA Damage Response Sunshin Kim, Dong Hwa Jun, Hye Jin Kim, Kyung-Chae Jeong, Chang-Hun Lee Journal of Biomolecular Screening 2011; February 2011 16: 259-265

Alexandra R. Grassian, Zachary T. Schafer1 and Joan S. Brugge ErbB2 Stabilizes Epidermal Growth Factor Receptor (EGFR) Expression via Erk and Sprouty2 in Extracellular Matrix-detached Cells The Journal of Biological Chemistry 2011; 2011 286: 79-90. First

Aaron J Urquhart, Magtouf Gatei, Derek J Richard, Kum Kum Khanna ATM mediated phosphorylation of CHD4 contributes to genome maintenance Genome Integrity 2011; 2:1

Shirin Arastu-Kapur, Janet L Anderl, Marianne Kraus, Francesco Parlati, Kevin D Shenk, Susan J Lee, Tony Muchamuel, Mark K Bennett, Christoph Driessen, Andrew J Ball and Christopher J Kirk Non-proteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events Clinical Cancer Research 2011; Published OnlineFirst March 1, 2011

Christina N. Ramirez, Tatsuya Ozawa, Toshimitsu Takagi, Christophe Antczak, David Shum, Robert Graves, Eric C. Holland and Hakim Djaballah Validation of a High Content Screening Assay Using Whole Well Imaging of Transformed Phenotypes ASSAY and Drug Development Technologies 2011; 9 Issue 3: May 25, 2011

Mei Yee Koh, Robert Lemos Jr, Xiuping Liu, and Garth Powis The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion Cancer Research 2011; June 1, 2011 71; 4015

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Xianmin Luo, Megan K Ruhland, Ermira Pazolli, Anne C Lind, and Sheila Stewart Osteopontin Stimulates Preneoplastic Cellular Proliferation Through Activation of the MAPK Pathway Molecular Cancer Research 2011; August 2011 9; 1018

Ahmed Ashour Ahmed, Xiaoyan Wang, Zhen Lu, Juliet Goldsmith, Xiao-Feng Le, Geoffrey Grandjean, Geoffrey Bartholomeusz, Bradley Broom, and Robert C. Bast Jr Modulating microtubule stability enhances the cytotoxic response of cancer cells to paclitaxel Cancer Research 2011; Published OnlineFirst July 20, 2011

Natalia N. Sergeeva, Marion Donnier-Marechal, Gisela M. Vaz, Anthony M. Davies, Mathias O. Senge Simple but powerful: Phenanthroline-based small molecules for cellular imaging and cancer screening Bioorganic & Medicinal Chemistry Letters 2011; Volume 21, Issue 15, 1 August 2011, Pages

4385-4388 Romel Somwar, Hediye Erdjument-Bromage, Erik Larsson, David Shum, William W. Lockwood, Guangli Yang, Chris Sander, Ouathek Ouerfelli, Paul J. Tempst, Hakim Djaballah, and Harold E. Varmus Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines PNAS 2011; September 27, 2011 vol. 108 no. 39 16375–16380

Xian-Yang Qin, Feifei Wei, Jun Yoshinaga, Junzo Yonemoto, Masaru Tanokura, Hideko Sone siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells FEBS Letters 2011; 585 (2011) 3310–3315

Lorenzo Veschini, Luca Crippa, Eleonora Dondossola, Claudio Doglioni, Angelo Corti and Elisabetta Ferrero The vasostatin-1 fragment of chromogranin A preserves a quiescent phenotype in hypoxia-driven endothelial cells and regulates tumor neovascularization The FASEB Journal 2011; Published online before print August 8, 2011

Thapi D. Rao, Nestor Rosales, and David R. Spriggs Dual-Fluorescence Isogenic High-Content Screening for MUC16/CA125 Selective Agents Molecular Cancer Therapeutics 2011; October 2011 10:1939-1948

Maite Verreault, Dita Strutt, Dana Masin, Malathi Anantha, Andrew Yung, Piotr Kozlowski, Dawn Waterhouse, Marcel B Bally, and Donald T Yapp Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine BMC Cancer 2011; 11: 124.

Wieslawa H Dragowska, Sherry A Weppler, Mohammed A Qadir, Ling Yan Wong, Yannick Franssen, Jennifer HE Baker, Anita I Kapanen, Guido JJ Kierkels, Dana Masin, Andrew I Minchinton, Karen A Gelmon and Marcel B Bally The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity BMC Cancer 2011; 11:420

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Isabelle Pouny, Chantal Etiévant, Laurence Marcourt, Isabelle Huc-Dumas, Muriel Batut, Frédéric Girard, Michel Wright, Georges Massiot Protoflavonoids from Ferns Impair Centrosomal Integrity of Tumor Cells Planta Med 2011; 77(5): 461-466

Ahmed Ashour Ahmed, Juliet Goldsmith, Izabela Fokt, Xiao-Feng Le, Krystiana A. Krzysko, Bogdan Lesyng, Robert C. Bast and Waldemar Priebe A genistein derivative, ITB-301, induces microtubule depolymerization and mitotic arrest in multidrug-resistant ovarian cancer Cancer Chemother Pharmacol 2011; 68:1033–1044

Yang, S-Q | Long, L | Li, W | Wang, L-L Establishment of mTEL-cFmskd eukaryotic expression vector and its effect on STAT1/3 nuclear translocation Chinese Journal of Pharmacology and Toxicology 2011; Vol. 25, no. 5, pp. 456-462. Oct 2011.

Yuka Nakazawa, Kensaku Sasaki, Norisato Mitsutake, Michiko Matsuse, Mayuko Shimada, Tiziana Nardo, Yoshito Takahashi, Kaname Ohyama, Kosei Ito, Hiroyuki Mishima, Masayo Nomura, Akira Kinoshita, Shinji Ono, Katsuya Takenaka, Ritsuko Masuyama, Takashi Kudo, Hanoch Slor, Atsushi Utani, Satoshi Tateishi, Shunichi Yamashita, Miria Stefanini, Alan R Lehmann, Koh-ichiro Yoshiura & Tomoo Ogi Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair Nature Genetics 2012; Volume:44, Pages:586–592

Sofie Claerhout, Bhaskar Dutta, Wouter Bossuyt, Fan Zhang, Catherine Nguyen-Charles, Jennifer B. Dennison, Qinghua Yu, Shuangxing Yu, Gábor Balázsi, Yiling Lu, Gordon B. Mills Abortive Autophagy Induces Endoplasmic Reticulum Stress and Cell Death in Cancer Cells PLoS ONE 2012; June 2012 | Volume 7 | Issue 6 | e39400

Tomoya Kinjo, Jun Ye, Hanxu Yan, Takeki Hamasaki, Hidekazu Nakanishi, Kazuko Toh, Noboru Nakamichi, Shigeru Kabayama, Kiichiro Teruya and Sanetaka Shirahata Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells Cytotechnology 2012; Volume 64, Number 3 (2012)

Katherine B. Chiappinelli, Brian C. Haynes, Michael R. Brent, and Paul J. Goodfellow Reduced DICER1 elicits an interferon response in endometrial cancer cells Molecular Cancer Research 2012; OnlineFirst January 17, 2012

D W Jun, Y S Jeong, H J Kim, K-C Jeong, S Kim, C-H Lee Characterization of DDRI-18 (3,3'-(1H,3'H-5,5'-bibenzo[d]imidazole-2,2'-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage response British Journal of Pharmacology 2012; accepted Article

Anders L. Nielsen, Line H. Kristensen, Karen B. Stephansen, Jan B.L. Kristensen, Charlotte Helgstrand, Michael Lees, Paul Cloos, Kristian Helin, Michael Gajhede, Lars Olsen Identification of catechols as histone–lysine demethylase inhibitors FEBS Letters 2012; Volume 586, Issue 8, 24 April 2012, Pages 1190–1194

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Bart Cornelissen, Andrew Waller, Carol Target, Veerle Kersemans, Sean Smart and Katherine A Vallis 111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin EJNMMI Research 2012, 2:9

Emanuele Marra, Fabio Palombo, Gennaro Ciliberto, Luigi Aurisicchio Intratumoral electro-transfer of small interfering RNA against kinesin spindle protein (KSP) slows down tumor progression Journal of Cellular Physiology 2012; Online First

C Lemaître, B Fischer, A Kalousi, A-S Hoffbeck, J Guirouilh-Barbat, O D Shahar, D Genet, M Goldberg, P Betrand, B Lopez, L Brino and E Soutoglou The nucleoporin 153, a novel factor in double-strand break repair and DNA damage response Oncogene 2012; online publication

Rama Adikrisna, Shinji Tanaka, Shunsuke Muramatsu, Arihiro Aihara, Daisuke Ban, Takanori Ochiai, Takumi Irie, Atsushi Kudo, Noriaki Nakamura, Shoji Yamaoka, Shigeki Arii Identification of Pancreatic Cancer Stem Cells and Selective Toxicity of Chemotherapeutic Agents Gastroenterology 2012; Volume 143, Issue 1 , Pages 234-245.e7, July 2012

Md. Rafiqul Islam, Hiromi Uramoto, Toshiaki Okada, Ravshan Z. Sabirov and Yasunobu Okada Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells American Journal of Physiology - Cell Physiology 2012; Online First

Wan Xing Hong, Jon Akutagawa, Steven Chen, Michelle Arkin, and Benjamin S. Braun Library screen to rapidly determine activity against normal and mutant bone marrow progenitor cells. Cancer Res., Apr 2013; 73: 5524.

Ada Leung, Brian Kwok, Daniel Ricaurte, Amith Ahluwalia, Mohammed A. Qadir, and Marcel B. Bally Silencing of PAPSS1 (3’-phosphoadenosine 5’-phosphosulfate synthase 1) potentiates cisplatin activity against non-small cell lung cancer. Cancer Res., Apr 2013; 73: 4362.

Eberhard Krausz, Ronald de Hoogt, Emmanuel Gustin, Frans Cornelissen, Thierry Grand-Perret, Lut Janssen, Nele Vloemans, Dirk Wuyts, Sandy Frans, Amy Axel, Pieter Johan Peeters, Brett Hall, and Miroslav Cik Translation of a Tumor Microenvironment Mimicking 3D Tumor Growth Co-culture Assay Platform to High-Content Screening J Biomol Screen, Jan 2013; 18: 54 - 66.

Yusuke Narita, Kiyoshi Okamoto, Megumi Ikemori Kawada, Kazuma Takase, Yukinori Minoshima, Kotaro Kodama, Masao Iwata, Norimasa Miyamoto, and Kohei Sawada Novel ATP-Competitive MEK Inhibitor E6201 Is Effective against Vemurafenib-Resistant Melanoma Harboring the MEK1-C121S Mutation in a Preclinical Model Mol. Cancer Ther., Apr 2014; 13: 823 - 832.

Hanan Khoury-Haddad, Noga Guttmann-Raviv, Inbal Ipenberg, David Huggins, Anand D. Jeyasekharan, and Nabieh Ayoub PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair PNAS, Feb 2014; 111: E728 - E737.

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RAJNEESH P. UZGARE, TIMOTHY P. SHEETS, and DANIEL S. JOHNSTON Evaluation of Melphalan, Oxaliplatin, and Paclitaxel in Colon, Liver, and Gastric Cancer Cell Lines in a Short-term Exposure Model of Chemosaturation Therapy by Percutaneous Hepatic Perfusion Anticancer Res, May 2013; 33: 1989 - 2000.

Loss of PPP2R2A Inhibits Homologous Recombination DNA Repair and Predicts Tumor Sensitivity to PARP Inhibition Peter Kalev, Michal Simicek, Iria Vazquez, Sebastian Munck, Liping Chen, Thomas Soin, Natasha Danda, Wen Chen, and Anna Sablina Cancer Res., Dec 2012; 72: 6414 - 6424.

Linbo Wang, Yang Zeng, Ye Liu, Xuansheng Hu, Shuhong Li, Yuepeng Wang, Ling Li, Zhongfang Lei, and Zhenya Zhang Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin Acta Biochim Biophys Sin, Oct 2014; 46: 877 - 884.

Manuel Sarmiento Soto, Sébastien Serres, Daniel C. Anthony, and Nicola R. Sibson Functional role of endothelial adhesion molecules in the early stages of brain metastasis Neuro Oncology, Apr 2014; 16: 540 - 551.

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response Yu-Fen Lin, Hung-Ying Shih, Zengfu Shang, Shinji Matsunaga, and Benjamin PC Chen Nucleic Acids Res., Apr 2014; 42: 4463 - 4473.

Sardar Faisal Mahmood, Nadège Gruel, Elodie Chapeaublanc, Aurianne Lescure, Thouis Jones, Fabien Reyal, Anne Vincent-Salomon, Virginie Raynal, Gaëlle Pierron, Franck Perez, Jacques Camonis, Elaine Del Nery, Olivier Delattre, François Radvanyi, and Isabelle Bernard-Pierrot A siRNA screen identifies RAD21, EIF3H, CHRAC1 and TANC2 as driver genes within the 8q23, 8q24.3 and 17q23 amplicons in breast cancer with effects on cell growth, survival and transformation Carcinogenesis, Mar 2014; 35: 670 - 682.

Gernot Neumayer, Angela Helfricht, Su Yeon Shim, Hoa Thi Le, Cecilia Lundin, Camille Belzil, Mathieu Chansard, Yaping Yu, Susan P. Lees-Miller, Oliver J. Gruss, Haico van Attikum, Thomas Helleday, and Minh Dang Nguyen Targeting Protein for Xenopus Kinesin-like Protein 2 (TPX2) Regulates -Histone 2AX (-H2AX) Levels upon Ionizing Radiation J. Biol. Chem., Dec 2012; 287: 42206 - 42222.

Nils H. Nicolay, Rebecca Carter, Stephanie B. Hatch, Niklas Schultz, Remko Prevo, W. Gillies McKenna, Thomas Helleday, and Ricky A. Sharma Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta Carcinogenesis, Nov 2012; 33: 2026 - 2034.

Adnan Elhammali, Joseph E. Ippolito, Lynne Collins, Jan Crowley, Jayne Marasa, and David Piwnica-Worms A High-Throughput Fluorimetric Assay for 2-Hydroxyglutarate Identifies Zaprinast as a Glutaminase Inhibitor Cancer Discovery, Jul 2014; 4: 828 - 839.

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Eberhard Krausz, Ronald de Hoogt, Emmanuel Gustin, Frans Cornelissen, Thierry Grand-Perret, Lut Janssen, Nele Vloemans, Dirk Wuyts, Sandy Frans, Amy Axel, Pieter Johan Peeters, Brett Hall, and Miroslav Cik Translation of a Tumor Microenvironment Mimicking 3D Tumor Growth Co-culture Assay Platform to High-Content Screening J Biomol Screen, Jan 2013; 18: 54 - 66.

Yi Huang, Hua-Chien Chen, Chao-Wei Chiang, Chau-Ting Yeh, Shu-Jen Chen, and Chen-Kung Chou Identification of a two-layer regulatory network of proliferation-related microRNAs in hepatoma cells Nucleic Acids Res., Nov 2012; 40: 10478 - 10493.

Cell Cycle Analysis Thomas, N. and Goodyer, I. D. Stealth Sensors: real-time monitoring of the cell cycle Targets Innovations in Genomics & Proteomics 2003; 2 26 – 33

Thomas, N. Lighting the circle of life: fluorescent sensors for covert surveillance of the cell cycle Cell Cycle 2003; 2 545 – 549

Thomas, N., Kenrick, M., Giesler, T., Kiser, G., Tinkler, H., and Stubbs, S. Characterization and gene expression profiling of a stable cell line expressing a cell cycle GFP sensor Cell Cycle 2005; 4 191 – 195

Stubbs, S. and Thomas, N. Dynamic green fluorescent protein sensors for high-content analysis of the cell cycle Methods Enzymol. 2006; 414 1 – 21

Michael Carleton, Mao Mao, Matthew Biery, Paul Warrener, Sammy Kim, Carolyn Buser, C. Gary Marshall, Christine Fernandes, James Annis, and Peter S. Linsley RNA Interference-Mediated Silencing of Mitotic Kinesin KIF14 Disrupts Cell Cycle Progression and Induces Cytokinesis Failure MOLECULAR AND CELLULAR BIOLOGY, May 2006, p. 3853–3863

Padfield, Dirk, Rittscher, Jens, Thomas, Nick, and Roysam, Badrinath Spatio-Temporal Cell Cycle Phase Analysis Using Level Sets and Fast Marching Methods Medical Image Analysis 2009; Volume 13, Issue 1, February 2009, Pages 143-155

Kimio Tanaka, Mansyur Arif and Nanao Kamada The usefulness of two-colour fluorescence in situ hybridization technique using chromosomal subset at metaphase and interphase stage in radiation biodosimetry Indian Journal of Science and Technology 2009; Vol.2 No 4 (Apr. 2009)

Siripan Limsirichaikul, Atsuko Niim, Heather Fawcett, Alan Lehmann, Shunichi Yamashita and Tomoo Ogi A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU) Nucleic Acids Research 2009; Vol. 37, No. 4 e31

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Halfdan Beck, Viola Nähse, Marie Sofie Yoo Larsen, Petra Groth, Trevor Clancy, Michael Lees1, Mette Jørgensen, Thomas Helleday, Randi G. Syljuåsen, and Claus Storgaard Sørensen Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase Journal of Biological Chemistry 2010; March 1, 2010 vol. 188no. 5 629-638

Silvia Dambacher, Wen Deng, Matthias Hahn, Dennis Sadic, Jonathan J. Fröhlich, Alexander Nuber, Christian Hoischen, Stephan Diekmann, Heinrich Leonhardt and Gunnar Schotta CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin Nucleus 2012; 3:1, 101–110; January/February 2012

Jakob Mejlvang, Yunpeng Feng, Constance Alabert, Kai J. Neelsen, Zuzana Jasencakova, Xiaobei Zhao, Michael Lees, Albin Sandelin, Philippe Pasero, Massimo Lopes, and Anja Groth New histone supply regulates replication fork speed and PCNA unloading J. Cell Biol., Jan 2014; 204: 29 - 43.

Yu-Fen Lin, Hung-Ying Shih, Zengfu Shang, Shinji Matsunaga, and Benjamin PC Chen DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response Nucleic Acids Res., Apr 2014; 42: 4463 - 4473.

Inflammation Mayer, Thomas, Jagla, Bernd, Wyler, Michael R., Kelly, Peter D., Aulner, Nathalie, Beard, Matthew, Barger, Geoffrey, T÷bben, Udo, Smith, Deborah H., Brand n, Lars, and Rothman, James E. Cell-Based Assays Using Primary Endothelial Cells to Study Multiple Steps in Inflammation Methods Enzymol. 2006; 414 266 – 283

Haasen, D, Merk, S, Seither, P, Martyres, D, Hobbie, S, and Heilker, R. Pharmacological Profiling of Chemokine Receptor-Directed Compounds Using High-Content Screening Journal of Biomolecular Screening 2008; 13 40 – 53

Navin K. Verma, Jennifer Dourlat, Anthony M. Davies, Aideen Long, Wang-Qing Liu, Christiane Garbay, Dermot Kelleher, and Yuri Volkov STAT3-Stathmin Interactions Control Microtubule Dynamics in Migrating T-cells Journal of Biological Chemistry 2009; Vol. 284, Issue 18, 12349-12362, May 1, 2009

Yoshiko Fujita, Akemi Kakino, Mariko Harada-Shiba, Yuko Sato, Kazunori Otsui, Ryo Yoshimoto and Tatsuya Sawamura C-Reactive Protein Uptake by Macrophage Cell Line via Class-A Scavenger Receptor Clinical Chemistry 2010; 56: 478-481, 2010.

Navin K. Verma, Eugene Dempsey, Michael Freeley, Catherine H. Botting, Aideen Long, Dermot Kelleher, Yuri Volkov Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells Journal of Cellular Physiology 2011; Volume 226, Issue 6, pages 1489–1498, June 2011

Tomoya SAKAMOTO, Yuko YAMAGUCHI, Tsuyoshi GOTO, Nobuyuki TAKAHASHI and Teruo KAWADA An in Vitro Analysis System Using a Fluorescence Protein Reporter for Evaluating Anti-Inflammatory Effects in Macrophages Bioscience, Biotechnology, and Biochemistry 2011; Vol. 75 (2011) , No. 8 pp.1582-1587

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Kyoko Shirakabe, Seisuke Hattori, Motoharu Seiki, Shigeo Koyasu and Yasunori Okada VIP36 Protein Is a Target of Ectodomain Shedding and Regulates Phagocytosis in Macrophage Raw 264.7 Cells The Journal of Biological Chemistry; 2011 286: 43154-43163

Michael Freeley, Francis O’Dowd, Toby Paul, Dmitry Kashanin, Anthony Davies, Dermot Kelleher and Aideen Long L-Plastin Regulates Polarization and Migration in Chemokine-Stimulated Human T Lymphocytes The Journal of Immunology 2012; June 15, 2012 vol. 188 no. 12 6357-6370

Livia Garzetti, Ramesh Menon, Annamaria Finardi, Alessandra Bergami, Antonio Sica, Gianvito Martino, Giancarlo Comi, Claudia Verderio, Cinthia Farina, and Roberto Furlan Activated macrophages release microvesicles containing polarized M1 or M2 mRNAs J. Leukoc. Biol., May 2014; 95: 817 - 825.

Jinfu Xie, Julie Zorman, Lani Indrawati, Melanie Horton, Keri Soring, Joseph M. Antonello, Yuhua Zhang, Susan Secore, Matthew Miezeiewski, Su Wang, Anthony D. Kanavage, Julie M. Skinner, Irene Rogers, Jean-Luc Bodmer, and Jon H. Heinrichs Development and Optimization of a Novel Assay To Measure Neutralizing Antibodies against Clostridium difficile Toxins Clin. Vaccine Immunol., Apr 2013; 20: 517 - 525.

Yonglian Sun, Patrick Caplazi, Juan Zhang, Anita Mazloom, Sarah Kummerfeld, Gabriel Quinones, Kate Senger, Justin Lesch, Ivan Peng, Andrew Sebrell, Wilman Luk, Yanmei Lu, Zhonghua Lin, Kai Barck, Judy Young, Mariela Del Rio, Sophie Lehar, Vida Asghari, WeiYu Lin, Sanjeev Mariathasan, Jason DeVoss, Shahram Misaghi, Mercedesz Balazs, Tao Sai, Benjamin Haley, Philip E. Hass, Min Xu, Wenjun Ouyang, Flavius Martin, Wyne P. Lee, and Ali A. Zarrin PILRα Negatively Regulates Mouse Inflammatory Arthritis J. Immunol., Jul 2014; 193: 860 - 870.

Kinases, Translocation and Cell Signaling Assays Joakim Lindblad, Carolina Wählby Ewert Bengtsson Alla Zaltsman Image analysis for automatic segmentation of cytoplasms and classification of Rac1 activation Cytometry Part A 2004; 57A 22 – 33

Olive, D. M Quantitative methods for the analysis of protein phosphorylation in drug development Expert Review in Proteomics 2004; 1 327 – 341

Lundholt, Betina Kerstin, Linde, Viggo, Loechel, Frosty, Pedersen, Hans Christian, Moller, Soren, Praestegaard, Morten, Mikkelsen, Ivan, Scudder, Kurt, Bjorn, Sara Petersen, Heide, Morten, Arkhammar, Per O. G., Terry, Robert, and Nielsen, Soren Jensby Identification of Akt Pathway Inhibitors Using Redistribution Screening on the FLIPR and the IN Cell 3000 Analyzer Journal of Biomolecular Screening 2005; 10 20 – 29

Granas, C., Lundholt, B.K., Loechel, F., Pedersoen, H-C., Bjorn, S.P., Linde, V., Krogh-Jensen, C., Nielsen, E-V.D., Praestegaard, M and Nielsen, S.J., Identification of RAS-Mitogen-Activated Protein Kinase Signaling Pathway Modulators in an ERF1 Redistribution Screen Journal of Biomolecular Screening 2006; 11 (4), 423-434

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Ross, Sandra, Chen, Teresa, Yu, Violeta, Tudor, Yanyan, Zhang, Dawei, Liu, Longbin, Tamayo, Nuria, Dominguez, Celia, and Powers, David High-Content Screening Analysis of the p38 Pathway: Profiling of Structurally Related p38alpha Kinase Inhibitors Using Cell-Based Assays ASSAY and Drug Development Technologies 2006; 4 397 – 409

Sun, T., Ye, F., Ding, H., Chen, K., Jiang, H., and Shen, X. Protein tyrosine phosphatase 1B regulates TGF beta 1-induced Smad2 activation through PI3 kinase-dependent pathway Cytokine 2006; 35 88 – 94

Wolff, M, Hassen, D., Merk, S. E., Kroner, M, Maier, U., Bordel, S., Wiedenmann, J., Nienhaus, G. U., Valler, M. J., and Heilker, R. Automated High Content Screening for Phosphoinositide 3 Kinase Inhibition Using an AKT1 Redistribution Assay Combinatorial Chemistry & High Throughput Screening 2006; 9 339 – 350

Ye, F., Sun, T., Ding, H., Luo, H, Chen, K., Shen, X., and Jiang, H. Quantitative Characterization of 15-Deoxy- Delta(12,14)-Prostaglandin J2 in Regulating EGFPSmad2 Translocation

in CHO Cells Through PPAR /TGF/Smad2 Pathway Cellular Physiol Biochem 2006; 18 143 – 150

Ye F, Sun T, Luo H, Ding H, Chen K, Shen X, Jiang H. Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway. Cellular Physiology and Biochemistry 2006; 18(1-3):143-50.

Ai Yamamoto, M. Laura Cremona, and James E. Rothman Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway The Journal of Cell Biology 2006; Feb 27;172(5):719-31.

Sun, T., Wang, Q., Yu, Z., Zhang, Y., Guo, Y., Chen, K., Shen, X., and Jiang, H. Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive cellular effects on PI3K/AKT activation, glucose transport, and TGFbeta/Smad2 signaling Chembiochem. 2007; 8 187 - 193

Caunt, C. J., Rivers, C. A., Conway-Campbell, B. L., Norman, M. R, and McArdle, C. EGF receptor and protein kinase C signalling to ERK2: Spaciotemporal regulation of ERK2 by dual-specificity phosphatases Journal of Biological Chemistry 2008; 283 6241 – 6252

Caunt, C. J., Armstrong, S. P, Rivers, C. A., Norman, M. R, and McArdle, C. Spatiotemporal regulation of ERK2 by dual-specificity phosphatases Journal of Biological Chemistry 2008; September 26, 283, 26612-26623.

Kourosh Zolghadr, Oliver Mortusewicz, Ulrich Rothbauer, Regina Kleinhans, Heike Goehler, Erich E. Wanker, M. Cristina Cardoso, and Heinrich Leonhardt A Fluorescent Two-hybrid Assay for Direct Visualization of Protein Interactions in Living Cells Molecular & Cellular Proteomics 2008; November 1, 7, 2279-2287.

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Marjo Simonen, Yvonne Ibig-Rehm, Gabriele Hofmann, Johann Zimmermann, Genevieve Albrecht, Maxime Magnier, Valerie Heidinger, and Daniela Gabriel High-Content Assay to Study Protein Prenylation Journal of Biomolecular Screening 2008; July 2008 vol. 13 no. 6 456-467

K. A. Gately, D. Stewart, D. Waller, A. Davies, and K. J. O'Byrne Phosphorylation and nuclear localisation of Akt is induced by hypoxia and associated with a poor prognosis in malignant pleural mesothelioma Journal of Clinical Oncology 2008; Vol 26, No 15S (May 20 Supplement), 2008: 22034

Masato Iida, Takanori Sasaki and Hideya Komatani Overexpression of Plk3 causes morphological change and cell growth suppression in Ras pathway-activated cells Journal of Biochemistry 2009; Oct; 146(4):501-7. Epub 2009 Jun 24.

Stephen Paul Armstrong, Christopher James Caunt and Craig Alexander McArdle Gonadotropin-Releasing Hormone and Protein Kinase C Signaling to ERK: Spatiotemporal Regulation of ERK by Docking Domains and Dual-Specificity Phosphatases Molecular Endocrinology 2009; 23 (4): 510-519

Amy L. Samuels, S. Peter Klinken, and Evan Ingley Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation Blood 2009; 16 April 2009, Vol. 113, No. 16, pp. 3845-3856.

Vincent Unterreiner, Yvonne Ibig-Rehm, Marjo Simonen, Hanspeter Gubler, Daniela Gabriel Comparison of Variability and Sensitivity between Nuclear Translocation and Luciferase Reporter Gene Assays Journal of Biomolecular Screening 2009; Vol. 14, No. 1, 59-65

Xie Yuli, Rinderspacher Alison, Liu Yidong, Gong Gangli, Smith Deborah H., Wyler Michael, Branden Lars, Deng, Shi-Xian Small-Molecule Modulators of the NF-κB Pathway Newly Identified by a Translocation-Based Cellular Assay Current Topics in Medicinal Chemistry 2009; Volume 9, Number 13, September 2009 , pp.

1172-1180(9) Simone Kredel, Michael Wolff, Jörg Wiedenmann, Barbara Moepps, G. Ulrich Nienhaus, Peter Gierschik, Barbara Kistler, and Ralf Heilker, Dr. CXCR2 Inverse Agonism Detected by Arrestin Redistribution Journal of Biomolecular Screening 2009; 14:1076.

Wyler MR, Smith DH, Cayanis E, Többen U, Aulner N, Mayer T. Cell-based assays to probe the ERK MAP kinase pathway in endothelial cells. Methods in Molecular Biology 2009;486:29-41.

Michael Freeley, Gabor Bakos, Anthony Davies, Dermot Kelleher, Aideen Long and Dara J. Dunican A High-Content Analysis Toolbox Permits Dissection of Diverse Signaling Pathways for T Lymphocyte Polarization Journal of Biomolecular Screening 2010; 15; 541

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Caunt CJ and McArdle CA Stimulus-induced uncoupling of extracellular signal-regulated kinase phosphorylation from nuclear translocation. Journal of Cell Science 2010; 123, 4310-4320 (2010)

Antje Grotemeier, Sebastian Alers, Simon G. Pfisterer, Florian Paasch, Merle Daubrawa, Alexandra Dieterle, Benoit Viollet, Sebastian Wesselborg, Tassula Proikas-Cezanne and Björn Stork AMPK-independent induction of autophagy by cytosolic Ca2+ increase Cellular Signalling 2010; Volume 22, Issue 6, June 2010, Pages 914-925

Michael Wolff, Simone Kredel, Dorothea Haasen, Jörg Wiedenmann, G. Ulrich Nienhaus, Barbara Kistler, Franz Oswald and Ralf Heilker High Content Screening of CXCR2-Dependent Signalling Pathways Combinatorial Chemistry & High Throughput Screening 2010; 2010, 13, 3-15

Navin K. Verma, Anthony M. Davies, Aideen Long, Dermot Kelleher and Yuri Volkov STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL Cellular & Molecular Biology Letters 2010; Volume 15, Number 2, 342-355

Qiong Liu, Yu Zhang, Zhonghui Lin, Hong Shen, Lili Chen, Lihong Hu, Hualiang Jiang and Xu Shen Danshen extract 15,16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-target pathways The Journal of Steroid Biochemistry and Molecular Biology 2010; Volume 120, Issues 4-5, June 2010,

Pages 155-163 Qiong Liu, Xu Wang, Yu Zhang, Chen-jing Li, Li-hong Hu and Xu Shen Leukamenin F suppresses liver fibrogenesis by inhibiting both hepatic stellate cell proliferation and extracellular matrix production Acta Pharmacologica Sinica 2010; 31, 839-848 (July 2010)

Anne-Marie Byrne, Eilis Foran, Ruchika Sharma, Anthony Davies, Ciara Mahon, Jacintha O’Sullivan, Diarmuid O’Donoghue, Dermot Kelleher and Aideen Long Bile acids modulate the Golgi membrane fission process via a protein kinase Cη and protein kinase D-dependent pathway in colonic epithelial cells Carcinogenesis 2010; (2010) 31 (4): 737-744.

David O Azorsa, RiLee H Robeson, Danielle Frost, Bessie Meec hoovet, Gillian R Brautigam, Chad Dickey, Christian Beaudry, Gargi D Basu, David R Holz, Joseph A Hernandez, Kristen M Bisanz, Leslie Gwinn, Andrew Grover, Joseph Rogers, Eric M Reiman, Michael Hutton, Dietrich A Stephan, Spyro Mousses, Travis Dunckley High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation BMC Genomics 2010; 2010, 11:25

Lirui Wang, Xu Wang, Jing Chen, Zhengyi Yang, Liang Yu, Lihong Hu, Xu Shen Activation of Protein Serine/Threonine Phosphatase PP2Ca Efficiently Prevents Liver Fibrosis PLoS ONE 2010; December 2010, Volume 5, Issue 12, e14230

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RiLee H. Robeson and Travis Dunckley High-Content RNA Interference Assay: Analysis of Tau Hyperphosphorylation as a Generic Paradigm Methods in Molecular Biology 2011; Volume 700, Part 3, 221-238

Wang, Chen; Wang, Lili; Zhao, Changqi Development of a Plate-Based Assay for High-Content Analysis of Individual Untethered Non-Adherent Cells Combinatorial Chemistry & High Throughput Screening 2011; Volume 14, Number 7, August 2011 ,

pp. 583-589(7) Takahiro Fujimoto, Takashi Machida, Toshiyuki Tsunoda, Keiko Doi, Takeharu Ota, Masahide Kuroki and Senji Shirasawa KRAS-induced actin-interacting protein regulates inositol 1,4,5-trisphosphate-receptor-mediated calcium release Biochemical and Biophysical Research Communications 2011; Volume 408, Issue 2, 6 May 2011,

Pages 214-217 Nikolaus Schultz, Dina R Marenstein, Dino A De Angelis, Wei-Qing Wang, Sven Nelander, Anders Jacobsen, Debora S Marks, Joan Massagué and Chris Sander Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2 Science. 2011; 2: 3.

Keiichi Sakakibara, Naoya Saito, Takuji Sato, Atsushi Suzuki, Yoko Hasegawa, Jonathan M. Friedman, Donald W. Kufe, Daniel D. VonHoff, Tadahiko Iwami and Takumi Kawabe CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity blood 2011; Prepublished online August 12, 2011; doi:10.1182/blood-2011-01-333138

Y Tabe, L Jin, K Iwabuchi, R-Y Wang, N Ichikawa, T Miida, J Cortes, M Andreeff and M Konopleva Role of stromal microenvironment in nonpharmacological resistance of CML to imatinib through Lyn/CXCR4 interactions in lipid rafts Leukemia 2011; (18 October 2011) | doi:10.1038/leu.2011.291

Josiah Gerdts, Yo Sasaki, Bhupinder Vohra, Jayne Marasa and Jeffrey Milbrandt Image-based Screening Identifies Novel Roles for IκB Kinase and Glycogen Synthase Kinase 3 in Axonal Degeneration Journal of Biological Chemistry 2011; 286, 28011-28018.

Simon G. Pfisterer, Mario Mauthe, Patrice Codogno and Tassula Proikas-Cezanne Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy Molecular Pharmacology December 2011; vol. 80 no. 6 1066-1075

Line H. Kristensen, Anders L. Nielsen, Charlotte Helgstrand, Michael Lees, Paul Cloos, Jette S. Kastrup, Kristian Helin, Lars Olsen, Michael Gajhede Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor FEBS Journal 2012; Volume 279, Issue 11, pages 1905–1914, June 2012

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Takashi Ono, Takahiro Miyazaki, Yoshihito Ishida, Masayoshi Uehata and Kazuhiro Nagata Direct in Vitro and in Vivo Evidence for Interaction between Hsp47 Protein and Collagen Triple Helix The Journal of Biological Chemistry 2012; 287, 6810-6818.

Hu, M. Katz, S. Chin, X. Qi, J. Cruz, C. Ibebunjo, S. Zhao, A. Chen, D. J. Glass, MNK2 Inhibits eIF4G Activation Through a Pathway Involving Serine-Arginine–Rich Protein Kinase in Skeletal Muscle. Science Signaling 2012; 14 February 2012 Vol. 5, Issue 211, p. ra14

Sonia C. P. Costa, Alexa M. Schmitz, Fathima F. Jahufar, Justin D. Boyd, Min Y. Cho, Marcie A. Glicksman, and Cammie F. Lesser A New Means To Identify Type 3 Secreted Effectors: Functionally Interchangeable Class IB Chaperones Recognize a Conserved Sequence mBio 2012; Volume 3 Issue 1 e00243-11

Ann R. Finch, Christopher J. Caunt, Rebecca M. Perrett, Krasimira Tsaneva-Atanasova, Craig A. McArdle Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases Cellular Signalling 2012; 24 (2012) 1002–1011

Britney L. Moss, Adnan Elhammali, Tiffanie Fowlkes, Shimon Gross, Anant Vinjamoori, Christopher H. Contag and David Piwnica-Worms Interrogation of IκBα:NF-κB (inhibitor of nuclear factor κB α:Nuclear factor κB) negative feedback loop dynamics: From single cells to live animals in vivo The Journal of Biological Chemistry 2012; Online First

Taichi Sugawaraa, Daiki Nakatsua, Hiroaki Kii, Nobuhiko Maiya, Atsuhiro Adachi, Akitsugu Yamamoto, Fumi Kano, Masayuki Murata PKCδ and ε regulate the morphological integrity of the ER–Golgi intermediate compartment (ERGIC) but not the anterograde and retrograde transports via the Golgi apparatus Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2012; Volume 1823, Issue 4, April

2012, Pages 861–875 Gakuro Harada, Qian Neng, Tsukasa Fujiki, and Yoshinori Katakura Molecular mechanisms for the p38-induced cellular senescence in normal human fibroblast J. Biochem., Nov 2014; 156: 283 - 290.

M. E. Bradley, B. Dombrecht, J. Manini, J. Willis, D. Vlerick, S. De Taeye, K. Van den Heede, A. Roobrouck, E. Grot, T. C. Kent, T. Laeremans, S. Steffensen, G. Van Heeke, Z. Brown, S. J. Charlton, and K. D. Cromie Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action Mol. Pharmacol., Jan 2015; 87: 251 - 262.

Seow Theng Ong, Michael Freeley, Joanna Skubis-Zegadło, Mobashar Hussain Urf Turabe Fazil, Dermot Kelleher, Friedrich Fresser, Gottfried Baier, Navin Kumar Verma, and Aideen Long Phosphorylation of Rab5a Protein by Protein Kinase C Is Crucial for T-cell Migration J. Biol. Chem., Jul 2014; 289: 19420 - 19434.

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Xian Xiao, Weidong Cao, Xiaofan Jiang, Wei Zhang, Yongqiang Zhang, Bolin Liu, Jinxiang Cheng, Huiyong Huang, Junli Huo, and Xiang Zhang Glaucocalyxin A, a negative Akt regulator, specifically induces apoptosis in human brain glioblastoma U87MG cells Acta Biochim Biophys Sin, Nov 2013; 45: 946 - 952.

Linda K. Rushworth, Andrew M. Kidger, Laurent Delavaine, Graeme Stewart, Susanne van Schelven, Jane Davidson, Christopher J. Bryant, Edward Caddye, Philip East, Christopher J. Caunt, and Stephen M. Keyse Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression PNAS, Dec 2014; 111: 18267 - 18272.

Larisa Yurlova, Maarten Derks, Andrea Buchfellner, Ian Hickson, Marc Janssen, Denise Morrison, Ian Stansfield, Christopher J. Brown, Farid J. Ghadessy, David P. Lane, Ulrich Rothbauer, Kourosh Zolghadr, and Eberhard Krausz The Fluorescent Two-Hybrid Assay to Screen for Protein–Protein Interaction Inhibitors in Live Cells: Targeting the Interaction of p53 with Mdm2 and Mdm4 J Biomol Screen, Apr 2014; 19: 516 - 525.

Nathan P. Coussens, Ryo Hayashi, Patrick H. Brown, Lakshmi Balagopalan, Andrea Balbo, Itoro Akpan, Jon C. D. Houtman, Valarie A. Barr, Peter Schuck, Ettore Appella, and Lawrence E. Samelson Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells Mol. Cell. Biol., Nov 2013; 33: 4140 - 4151.

Sarah Huntwork-Rodriguez, Bei Wang, Trent Watkins, Arundhati Sengupta Ghosh, Christine D. Pozniak, Daisy Bustos, Kim Newton, Donald S. Kirkpatrick, and Joseph W. Lewcock JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis J. Cell Biol., Sep 2013; 202: 747 - 763.

Rebecca M Perrett, Robert C. Fowkes, Christopher J. Caunt, Krasimira Tsaneva-Atanasova, Clive G. Bowsher, and Craig A. McArdle Signaling to Extracellular Signal-regulated Kinase from ErbB1 Kinase and Protein Kinase C: FEEDBACK, HETEROGENEITY, AND GATING J. Biol. Chem., Jul 2013; 288: 21001 - 21014.

Gopuraja Dharmalingam, SiDe Li, Efstathia Thymiakou, Thomas Carroll, Bernd B Zeisig, Chi Wai Eric So, Gordon Peters, Vasso Episkopou, Martin J Walsh, and Jesús Gil Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation Nadine Martin, Nikolay Popov, Francesca Aguilo, Ana O'Loghlen, Selina Raguz, Ambrosius P Snijders, EMBO J., Apr 2013; 32: 982 - 995.

Pei-Tzu Yang, Jamie N. Anastas, Rachel A. Toroni, Michi M. Shinohara, Jamie M. Goodson, Anja K. Bosserhoff, Andy J. Chien, and Randall T. Moon WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis EMBO Mol Med., Dec 2012; 4: 1294 - 1307.

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Rebecca M. Perrett, Margaritis Voliotis, Stephen P. Armstrong, Robert C. Fowkes, George R. Pope, Krasimira Tsaneva-Atanasova, and Craig A. McArdle Pulsatile Hormonal Signaling to Extracellular Signal-regulated Kinase: EXPLORING SYSTEM SENSITIVITY TO GONADOTROPIN-RELEASING HORMONE PULSE FREQUENCY AND WIDTH J. Biol. Chem., Mar 2014; 289: 7873 - 7883.

Marita G. Overhoff, James C. Garbe, James Koh, Martha R. Stampfer, David H. Beach, and Cleo L. Bishop Cellular senescence mediated by p16INK4A-coupled miRNA pathways Nucleic Acids Res., Feb 2014; 42: 1606 - 1618.

Membrane transporters Yamaguchi, H, Kobayashi, M, Okada, M, Takeuchi, T, Unno, M, Abe, T, Goto, J, Hishinuma, T, and Mano, N Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes Cancer Letters 2008; 260 163 – 169

Hong Shen, Yu Zhang, Hong Ding, Xu Wang, Lili Chen, Hualiang Jiang and Xu Shen Farnesoid X Receptor Induces GLUT4 Expression Through FXR Response Element in the GLUT4 Promoter Cell Physiol Biochem 2008;22:01-14

Paul Nicklin, Philip Bergman, Bailin Zhang, Ellen Triantafellow, Henry Wang, Beat Nyfeler, Haidi Yang, Marc Hild, Charles Kung, Christopher Wilson, Vic E. Myer, Jeffrey P. MacKeigan, Jeffrey A. Porter, Y. Karen Wang, Lewis C. Cantley, Peter M. Finan and Leon O. Murphy Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy Cell 2009; Volume 136, Issue 3, 6 February 2009, Pages 521-534

Daniela Baus, Yongping Yan, Zhuyin Li, Tina Garyantes, Meltsje de Hoop and Norbert Tennagels A robust assay measuring GLUT4 translocation in rat myoblasts overexpressing GLUT4-myc and AS160_v2 Analytical Biochemistry 2010; Volume 397, Issue 2, 15 February 2010, Pages 233-240

Hiroaki Yamaguchi, Toshiko Takeuchi, Masahiro Okada, Minako Kobayashi, Michiaki Unno, Takaaki Abe, Junichi Goto, Takanori Hishinuma, Miki Shimada and Nariyasu Mano Screening of Antibiotics That Interact with Organic Anion-Transporting Polypeptides 1B1 and 1B3 Using Fluorescent Probes Biological & Pharmaceutical Bulletin 2011; Vol. 34 (2011) , No. 3 389-395

Satoshi Uchida, Keiji Itaka, Qixian Chen, Kensuke Osada, Kanjiro Miyata, Takehiko Ishii, Mariko Harada-Shiba and Kazunori Kataoka Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N’-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity Journal of Controlled Release 2011; 2011 Oct 30;155(2):296-302. Epub 2011 May 5.

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Tomoya Suma, Kanjiro Miyata, Takehiko Ishii, Satoshi Uchida, Hirokuni Uchida, Keiji Itaka, Nobuhiro Nishiyama, Kazunori Kataoka Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain Biomaterials 2012; Volume 33, Issue 9, March 2012, Pages 2770–2779

Satoshi Uchida, Keiji Itaka, Qixian Chen, Kensuke Osada, Takehiko Ishii, Masa-Aki Shibata, Mariko Harada-Shiba and Kazunori Kataoka PEGylated Polyplex With Optimized PEG Shielding Enhances Gene Introduction in Lungs by Minimizing Inflammatory Responses Molecular Therapy 2012; 20, 1196-1203 (June 2012)

Md. Rafiqul Islam, Hiromi Uramoto, Toshiaki Okada, Ravshan Z. Sabirov, and Yasunobu Okada Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells Am J Physiol Cell Physiol, Nov 2012; 303: C924 - C935.

Neuronal studies (including neurite outgrowth) Ramm, P., Alexandrov, Y., Cholewinski, A., Cybuch, Y., Nadon, R., and Soltys, B. J. Automated screening of neurite outgrowth Journal of Biomolecular Screening 2003; 8 7 – 18

Battle, Daniel J., Lau, Chi Kong, Wan, Lili, Deng, Hongying, Lotti, Francesco, and Dreyfuss, Gideon The Gemin5 Protein of the SMN Complex Identifies snRNAs Molecular Cell 2006; 23 273 – 279

Danzer, K. M., Haasen, D, Karow, A. R., Moussaud, S, Habeck, M, Giese, A, Kretzschmar, H, Hengerer, B, and Kostka, M Different Species of {alpha}-Synuclein Oligomers Induce Calcium Influx and Seeding Journal of Neuroscience 2007; 27 9220 – 9232

Li, F., Zhou, X., Zhu, J., Ma, J., Huang, X., and Wong, S. T. High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles BMC.Biotechnol. 2007; 7 66

Rainey-Smith, Stephanie, Schroetke, Lars Wilhelm, Bahia, Parmvir, Fahmi, Ahmed, Skilton, Rachel, Spencer, Jeremy P. E., Rice-Evans, Catherine, Rattray, Marcus, and Williams, Robert J. Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation Neuroscience Letters 2008; 438 29 - 33

MacInnes, N, Iravani, M, Perry, E, Piggott, M, Perry, R, Jenner, P, and Ballard, C Proteasomal abnormalities in cortical Lewy body disease and the impact of proteasomal inhibition within cortical and cholinergic systems Journal of Neural Transmission 2008; 115 869 – 878

Derek B Oien, Heather E Shinogle, David S Moore, Jackob Moskovitz Clearance and Phosphorylation of Alpha-Synuclein Are Inhibited in Methionine Sulfoxide Reductase A Null Yeast Cells Journal of Molecular Neuroscience 2009; 39:323–332

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Hong Zhao, M.D., Ph.D., Carol Tang, Ph.D., Kemi Cui, M.D., Ph.D., Beng-Ti Ang, M.D. and Stephen T. C. Wong, Ph.D A screening platform for glioma growth and invasion using bioluminescence imaging Journal of Neurosurgery 2009; Aug 2009, Vol. 111, No. 2, Pages 238-246 Janet L Anderl, Stella Redpath, Andrew J Ball A Neuronal and Astrocyte Co-Culture Assay forHigh Content Analysis of Neurotoxicity Journal of Visualized Experiments 2009 K Matsumoto, C Sato, Y Naka, R Whitby, N Shimizu Stimulation of neuronal neurite outgrowthusing functionalized carbon nanotubes Nanotechnology 2010; 21 115101

Melanie Gerard,Ange´lique Deleersnijder, Veronique Danie¨ls, Sarah Schreurs, Sebastian Munck,Veerle Reumers, Hans Pottel, Yves Engelborghs, Chris Van den Haute, Jean-Marc Taymans,Zeger Debyser, Veerle Baekelandt Inhibition of FK506 Binding Proteins Reduces a-Synuclein Aggregation and Parkinson’s Disease-Like Pathology The Journal of Neuroscience 2010; February 17, 2010 • 30(7):2454 –2463

W. Kelly Yan, Marjo Goette, Gabriele Hofmann, Isabel Zaror and Janet Sim High-level soluble expression, purification and characterization of active human midkine from Escherichia coli Protein Expression and Purification 2010; Volume 70, Issue 2, April 2010, Pages 270-276

Caroline R. Elliott-Hunt, Fiona E. Holmes, Dean M. Hartley, Sylvia Perez, Elliott J. Mufson, David Wynick Endogenous Galanin Protects Mouse Hippocampal Neurons Against Amyloid Toxicity in vitro via Activation of Galanin Receptor-2 Journal of Alzheimer's Disease 2011; Volume 25, Number 3

Angelique Deleersnijder, Anne-Sophie Van Rompuy, Linda Desender, Hans Pottel, Luc Buee, Zeger Debyser, Veerle Baekelandt and Melanie Gerard Comparative analysis of different peptidyl-prolyl isomerases reveals FK506-binding protein 12 as the most potent enhancer of α-synuclein aggregation The Journal of Biological Chemistry 2011; Published on June 7, 2011

Bavo Heeman, Chris Van den Haute1, Sarah-Ann Aelvoet, Federica Valsecchi, Richard J. Rodenburg, Veerle Reumers, Zeger Debyser, Geert Callewaert, Werner J. H. Koopman, Peter H. G. M. Willems and Veerle Baekelandt Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance Journal of Cell Sciences 2011; 124:1115-1125

H. Elbrønd-Bek1, A. Wellejus , 1, , N.M. Kelly, M.S. Weidner, S.H. Jørgensen 2-(Cyclohexylamino)-1-(4-cyclopentylpiperazin-1-yl)-2-methylpropan-1-one, a novel compound with neuroprotective and neurotrophic effects in vitro Neurochemistry International 2011; Volume 59, Issue 6, November 2011, Pages 821-829

Sophie Parmentier-Batteur, Eleftheria N. Finger, Raghu Krishnan, Hemaka A. Rajapakse, John M. Sanders, Geeta Kandpal, Hong Zhu, Keith P. Moore, Christopher P. Regan, Sujata Sharma, J. Fred Hess, Theresa M. Williams, Ian J. Reynolds, Joseph P. Vacca, Robert J. Mark, Philippe G. Nantermet Attenuation of scratch-induced reactive astrogliosis by novel EphA4 kinase inhibitors Journal of Neurochemistry 2011; 118, 1016–1031.

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Thomas H.Hutson, WilliamJ.Buchser, JohnL.Bixby, VanceP.Lemmon and LawrenceD.F.Moon Optimization of a 96-well electroporation assay for postnatal rat CNS neurons suitable for cost–effective medium-throughput screening of genes that promote neurite outgrowth Frontiers in Molecular Neuroscience 2011; December 2011|Volume4|Article55

Chang Jun Lin, Han Chang Huang, Wen Juan Liu, Zhao Feng Jiang Biomedical Imaging and Visualization Model of Mitochondrial Dysfunction and Oxidative Stress in Alzheimer Disease Applied Mechanics and Materials 2011; 138-139, 1179

Thomas H. Hutson, Edmund Foster, John M. Dawes, Robert Hindges, Rafael J. Yáñez-Muñoz, Lawrence D. F. Moon Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones The Journal of Gene Medicine 2012; Volume 14, Issue 5, pages 299–315, May 2012

Anna Cozzi, Paolo Santambrogio, Daniela Privitera, Vania Broccoli, Luisa Ida Rotundo, Barbara Garavaglia, Rudolf Benz, Sandro Altamura, Jeroen S. Goede, Martina U. Muckenthaler, and Sonia Levi Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome J. Exp. Med., Aug 2013; 210: 1779 - 1791.

D. J. Culley, E. K. Cotran, E. Karlsson, A. Palanisamy, J. D. Boyd, Z. Xie, and G. Crosby Isoflurane affects the cytoskeleton but not survival, proliferation, or synaptogenic properties of rat astrocytes in vitro Br. J. Anaesth., Jun 2013; 110: i19 - i28.

Paolo La Montanara, Laura Rusconi, Albina Locarno, Lia Forti, Isabella Barbiero, Marco Tramarin, Chetan Chandola, Charlotte Kilstrup-Nielsen, and Nicoletta Landsberger Synaptic Synthesis, Dephosphorylation, and Degradation: A NOVEL PARADIGM FOR AN ACTIVITY-DEPENDENT NEURONAL CONTROL OF CDKL5 J. Biol. Chem., Feb 2015; 290: 4512 - 4527.

Hideo Shichinohe, Takeshi Ishihara, Koji Takahashi, Yoshikazu Tanaka, Michiyuki Miyamoto, Tomohiro Yamauchi, Hisayasu Saito, Hiroshi Takemoto, Kiyohiro Houkin, and Satoshi Kuroda Bone Marrow Stromal Cells Rescue Ischemic Brain by Trophic Effects and Phenotypic Change Toward Neural Cells Neurorehabil Neural Repair, Jan 2015; 29: 80 - 89.

Noninvasive Bioluminescence Imaging of α-Synuclein Oligomerization in Mouse Brain Using Split Firefly Luciferase Reporters Sarah-Ann Aelvoet, Abdelilah Ibrahimi, Francesca Macchi, Rik Gijsbers, Chris Van den Haute, Zeger Debyser, and Veerle Baekelandt J. Neurosci., Dec 2014; 34: 16518 - 16532.

William W Hwang, Ryan D Salinas, Jason J Siu, Kevin W Kelley, Ryan N Delgado, Mercedes F Paredes, Arturo Alvarez-Buylla, Michael C Oldham, and Daniel A Lim Distinct and separable roles for EZH2 in neurogenic astroglia eLife Sci, Jan 2014; 3: e02439.

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Sabrina Büttner, Lukas Habernig, Filomena Broeskamp, Doris Ruli, F Nora Vögtle, Manolis Vlachos, Francesca Macchi, Victoria Küttner, Didac Carmona-Gutierrez, Tobias Eisenberg, Julia Ring, Maria Markaki, Asli Aras Taskin, Stefan Benke, Christoph Ruckenstuhl, Ralf Braun, Chris Van den Haute, Tine Bammens, Anke van der Perren, Kai-Uwe Fröhlich, Joris Winderickx, Guido Kroemer, Veerle Baekelandt, Nektarios Tavernarakis, Gabor G Kovacs, Jörn Dengjel, Chris Meisinger, Stephan J Sigrist, and Frank Madeo Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease EMBO J., Nov 2013; 32: 3041 - 3054.

Yervand Eduard Karapetyan, Gian Franco Sferrazza, Minghai Zhou, Gregory Ottenberg, Timothy Spicer, Peter Chase, Mohammad Fallahi, Peter Hodder, Charles Weissmann, and Corinne Ida Lasmézas Unique drug screening approach for prion diseases identifies tacrolimus and astemizole as antiprion agents PNAS, Apr 2013; 110: 7044 - 7049.

Carmela Sidrauski, Diego Acosta-Alvear, Arkady Khoutorsky, Punitha Vedantham, Brian R Hearn, Han Li, Karine Gamache, Ciara M Gallagher, Kenny K-H Ang, Chris Wilson, Voytek Okreglak, Avi Ashkenazi, Byron Hann, Karim Nader, Michelle R Arkin, Adam R Renslo, Nahum Sonenberg, and Peter Walter Pharmacological brake-release of mRNA translation enhances cognitive memory eLife Sci, Jan 2013; 2: e00498.

Kathrin Meyer, Laura Ferraiuolo, Carlos J. Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A. Smith, John Ravits, Arthur H. Burghes, Pamela J. Shaw, Don W. Cleveland, Stephen J. Kolb, and Brian K. Kaspar Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS PNAS, Jan 2014; 111: 829 - 832.

Receptors (including Receptor Internalization) Oakley, Robert H., Hudson, Christine C., Cruickshank, Rachael D., Meyers, Diane M., Payne, Richard E., Rhem, Shay M., and Loomis, Carson R. The Cellular Distribution of Fluorescently Labeled Arrestins Provides a Robust, Sensitive, and Universal Assay for Screening G Protein-Coupled Receptors ASSAY and Drug Development Technologies 2002; 1 21 – 30

Milligan, G. High-content assays for ligand regulation of G-protein-coupled receptors Drug Discovery Today 2003; 8 579 – 585

Granas, C, Lundholt, B, Betina, K, Heydorn, A, Linde, V, Pedersen, H-C, Krog-Jensen, C, Rosenkilde, M. M, and Pagliaro, L. High Content Screening for G Protein-Coupled Receptors Using Cell-Based Protein Translocation Assays Combinatorial Chemistry & High Throughput Screening 2005; 8 301 – 309

Dorothea Hassen, Andreas Schnapp, Martin J. Valler and Ralf Heilker, G Protein-Coupled Receptor Internalization Assays in the High-Content Screening Format Methods in Enzymology 2005; 414, 121-139

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Hassen, D., Wolff, M. C., Valler, M. J., and Heilker, R. Comparison of G-Protein Coupled Receptor Desensitization-Related B-Arrestin Redistribution Using Confocal and Non-Confocal Imaging Combinatorial Chemistry & High Throughput Screening 2007; 9 37 – 47

Ross, D. A., Lee, S., Reiser, V., Xue, J., Alves, K., Vaidya, S., Kreamer, A., Mull, R., Hudak, E., Hare, T., Detmers, P. A., Lingham, R., Ferrer, M., Strulovici, B., and Santini, F. Multiplexed Assays by High-Content Imaging for Assessment of GPCR Activity Journal of Biomolecular Screening 2008; 13 449 – 455

Finch, A. R., Sedgley, K. R., Caunt, C. J., and McArdle, C. A. Plasma membrane expression of GnRH receptors: regulation by antagonists in breast, prostate, and gonadotrope cell lines J.Endocrinol. 2008;196 353 – 367

Michael Wolff, Stefan G. Kauschke, Susanne Schmidt, and Ralf Heilker Activation and Translocation of Glucokinase in Rat Primary Hepatocytes Monitored by High Content Image Analysis Journal of Biomolecular Screening 2008; vol. 13 no. 9 837-846

H Garside, A Stewart, N Brown, EL Cooke, M Graham, and M Sullivan Quantitative analysis of aryl hydrocarbon receptor activation using fluorescence-based cell imaging--a high-throughput mechanism-based assay for drug discovery. Xenobiotica 2008; Vol. 38, No. 1, January 2008, 1–20

Yoshitaka Sogawa, Akiko Shimizugawa, Takao Ohyama, Hiroaki Maeda, and Kazuki Hirahara The Pyrazolone Originally Reported to Be a Formyl Peptide Receptor (FPR) 2/ALX–Selective Agonist Is Instead an FPR1 and FPR2/ALX Dual Agonist Journal of Pharmacological Sciences 2009; 111, 317 – 321 (2009)3

Ann R. Finch, Christopher J. Caunt, Stephen P. Armstrong, and Craig A. McArdle Agonist-induced internalization and down regulation of gonadotropin-releasing hormone receptors American Journal of Physiology - Cell Physiology 2009; 297: C591-C600, 2009.

Maru BS, Tobias JT, Rivers C, Caunt CJ, Norman MR and McArdle CA An estrogen-glucocorticoid receptor chimera senses tissue selective estrogenic activity. Bone 2009; 44:102-12 Atsuhiro Adachi, Fumi Kano, Takaomi C. Saido, and Masayuki Murata Visual screening and analysis for kinase-regulated membrane trafficking pathways that are involved in extensive beta-amyloid secretion. Genes to Cells 2009; Mar;14(3):355-69. Epub 2009 Feb 13.

Ann R. Finch, Christopher J. Caunt, Stephen P. Armstrong, and Craig A. McArdle Plasma Membrane Expression of Gonadotropin-Releasing Hormone Receptors_Regulation by Peptide and Nonpeptide Antagonists Molecular Endocrinology 2010; 24:423-435

Armstrong SP, Caunt CJ, Fowkes RC, Tsaneva-Atanasova K, McArdle CA Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the ERK signaling pathway decode GnRH pulse frequency? Journal of Biological Chemistry 2010; VOLUME 285, NUMBER 32, AUGUST 6, 2010

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Caunt CJ, Armstrong SP and McArdle CA Using high content microscopy to study gonadotrophin-releasing hormone (GnRH) regulation of extracellular signal regulated kinase (ERK). Methods in Molecular Biology 2010; 2010, Volume 661, Part 6, 507-524 Finch AR, Sedgley K, Armstrong SP, Caunt CJ and McArdle CA Trafficking and signalling of gonadotrophin-releasing hormone receptors: a high content imaging approach. British Journal of Pharmacology 2010; 159:751-60 Michael Wolff, Kay Tetzlaff, Michael C. Nivens, Franz-Josef Schneider, Birgit Jung, Jens Hohlfeld and Ralf Heilker In vivo inhibition of epidermal growth factor receptor autophosphorylation prevents receptor internalization Experimental Cell Research 2010; 2011 Jan 1;317(1):42-50. Epub 2010 Sep 18.

AR Finch, KR Sedgley, SP Armstrong, CJ Caunt, CA McArdle

Trafficking and signalling of gonadotrophin‐releasing hormone receptors: an automated imaging

approach British Journal of Pharmacology 2010; Volume 159, Issue 4, pages 751–760, February 2010

Wei Chen, Huoling Tang, Hongying Liu, Long Long, Zehui Gong, Jianquan Zheng, Mugen Chi, Yunde Xie, Zhibing Zheng, Song Li and Lili Wang Novel selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models European Journal of Pharmacology 2010; Volume 637, Issues 1-3, 10 July 2010, Pages 178-185

Gregory D. Stewart, Patrick M. Sexton and Arthur Christopoulos Detection of Novel Functional Selectivity at M3 Muscarinic Acetylcholine Receptors Using a Saccharomyces cerevisiae Platform ACS Chemical Biology 2010; 2010, 5 (4), pp 365–375

Gregory D. Stewart, Patrick M. Sexton and Arthur Christopoulos Prediction of Functionally Selective Allosteric Interactions at an M3 Muscarinic Acetylcholine Receptor Mutant Using Saccharomyces cerevisiae Molecular Pharmacology 2010; August 2010 vol. 78 no. 2 205-214

Synthesis and structure–activity relationship of N-(2-arylethyl) isoquinoline derivatives as human scavenger receptor CD36 antagonists Yan-Xiang Wang, Li Wang, Yan-Ni Xu, Ying-Hong Li, Jian-Dong Jiang, Shu-Yi Si, Yang-Biao Li, Gang Ren, Yong-Qiang Shan, Bin Hong and Dan-Qing Song European Journal of Medicinal Chemistry 2011; Volume 46, Issue 4, April 2011, Pages 1066-1073

Simone Kredel, Michael Wolff, Silke Hobbie, Michael Bieler, Peter Gierschik, Ralf Heilker High-Content Analysis of CCR2 Antagonists on Human Primary Monocytes Journal of Biomolecular Screening 2011; August 2011 vol. 16 no. 7 683-693

Becky L. Conway-Campbell, Charlotte L. George, John R. Pooley, David M. Knight, Michael R. Norman, Gordon L. Hager and Stafford L. Lightman The HSP90 Molecular Chaperone Cycle Regulates Cyclical Transcriptional Dynamics of the Glucocorticoid Receptor and Its Coregulatory Molecules CBP/p300 During Ultradian Ligand Treatment Molecular Endocrinology 2011; June 1, 2011 vol. 25 no. 6 944-954

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Kim Wilkinson, Justin D. Boyd, Marcie Glicksman, Kathryn J. Moore and Joseph El Khoury A High Content Drug Screen Identifies Ursolic Acid as an Inhibitor of Amyloid β Protein Interactions with Its Receptor CD36 Journal of Biological Chemistry 2011; 2011 286: 34914-34922.

Wei Chen, Cheng Xu, Hong-ying Liu, Long Long, Wei Zhang, Zhi-bing Zheng, Yun-de Xie, Li-li Wang and Song Li Novel selective cannabinoid CB1 receptor antagonist MJ08 with potent in vivo bioactivity and inverse agonistic effects Acta Pharmacologica Sinica 2011; 32, 1148-1158 (September 2011)

Naoko Seki, Uhi Toh, Koji Kawaguchi, Masayuki Ninomiya, Mamoru Koketsu, Kunitomo Watanabe, Masatora Aoki, Teruhiko Fujii, Anna Nakamura, Yoshito Akagi, Jingo Kusukawa, Masayoshi Kage, Kazuo Shirouzu, Hideaki Yamana Tricin inhibits proliferation of human hepatic stellate cells in vitro by blocking tyrosine phosphorylation of PDGF receptor and its signaling pathways Journal of Cellular Biochemistry 2012; Volume 113, Issue 7, pages 2346–2355, July 2012

Christophe Antczak, Alun Bermingham, Paul Calder, Dmitry Malkov, Keming Song, John Fetter, and Hakim Djaballah Domain-Based Biosensor Assay to Screen for Epidermal Growth Factor Receptor Modulators in Live Cells ASSAY and Drug Development Technologies 2012; VOL. 10 NO. 1 FEBRUARY 2012

Yi Bao, Li Wang, Yanni Xu, Yuan Yang, Lifei Wang, Shuyi Si, Sunghee Cho, Bin Hong Salvianolic acid B inhibits macrophage uptake of modified low density lipoprotein (mLDL) in a scavenger receptor CD36-dependent manner Atherosclerosis 2012; Volume 223, Issue 1, July 2012, Pages 152–159

Guadalupe Rivero, Javier Llorente, Jamie McPherson, Alex Cooke, Stuart J. Mundell, Craig A. McArdle, Elizabeth M. Rosethorne, Steven J. Charlton, Cornelius Krasel, Christopher P. Bailey, Graeme Henderson and Eamonn Kelly Endomorphin-2: A Biased Agonist at the μ-Opioid Receptor Molecular Pharmacolgy 2012; August 2012 82:178-188

Meritxell Canals, J. Robert Lane, Adriel Wen, Peter J. Scammells, Patrick M. Sexton and Arthur Christopoulos A Monod-Wyman-Changeux Mechanism Can Explain G Protein-coupled Receptor (GPCR) Allosteric Modulation The Journal of Biological Chemistry 2012; 287, 650-659

Anna E. Davey, Katie Leach, Celine Valant, Arthur D. Conigrave, Patrick M. Sexton and Arthur Christopoulos Positive and Negative Allosteric Modulators Promote Biased Signaling at the Calcium-Sensing Receptor Endocrinology 2012; March 1, 2012 vol. 153 no. 3 1232-1241

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Brandon B. Holmes, Sarah L. DeVos, Najla Kfoury, Mei Li, Rachel Jacks, Kiran Yanamandra, Mohand O. Ouidja, Frances M. Brodsky, Jayne Marasa, Devika P. Bagchi, Paul T. Kotzbauer, Timothy M. Miller, Dulce Papy-Garcia, and Marc I. Diamond Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds PNAS, Aug 2013; 110: E3138 - E3147.

Sequence-dependent Internalization of Aggregating Peptides José R. Couceiro, Rodrigo Gallardo, Frederik De Smet, Greet De Baets, Pieter Baatsen, Wim Annaert, Kenny Roose, Xavier Saelens, Joost Schymkowitz, and Frederic Rousseau J. Biol. Chem., Jan 2015; 290: 242 - 258.

Anita Johswich, Christine Longuet, Judy Pawling, Anas Abdel Rahman, Michael Ryczko, Daniel J. Drucker, and James W. Dennis N-Glycan Remodeling on Glucagon Receptor Is an Effector of Nutrient Sensing by the Hexosamine Biosynthesis Pathway J. Biol. Chem., Jun 2014; 289: 15927 - 15941.

Yokoyama, Satoshi Nakamizo, Kenji Kabashima, Shuh Narumiya, Takao Shimizu, and Takehiko Yokomizo 12-hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor Min Liu, Kazuko Saeki, Takehiko Matsunobu, Toshiaki Okuno, Tomoaki Koga, Yukihiko Sugimoto, Chieko J. Exp. Med., Jun 2014; 211: 1063 - 1078.

Dane D. Jensen, Cody B. Godfrey, Christian Niklas, Meritxell Canals, Martina Kocan, Daniel P. Poole, Jane E. Murphy, Farzad Alemi, Graeme S. Cottrell, Christoph Korbmacher, Nevin A. Lambert, Nigel W. Bunnett, and Carlos U. Corvera The Bile Acid Receptor TGR5 Does Not Interact with β-Arrestins or Traffic to Endosomes but Transmits Sustained Signals from Plasma Membrane Rafts J. Biol. Chem., Aug 2013; 288: 22942 - 22960.

Masakatsu Suzuki, Sachiko Takaishi, Miyuki Nagasaki, Yoshiko Onozawa, Ikue Iino, Hiroaki Maeda, Tomoaki Komai, and Tomiichiro Oda Medium-chain Fatty Acid-sensing Receptor, GPR84, Is a Proinflammatory Receptor J. Biol. Chem., Apr 2013; 288: 10684 - 10691.

Toxicology (including apoptosis) Rodriguez, R A., Alfonso, J, O'Day, C, Ovechkina, Y, and Ward, C 297 Distinct Cell Lines: A High-Content Analysis Assay and a Full-Automation Design Solely Using Noncontact Liquid Dispensing Journal of the Association for Laboratory Automation 2007; 12 318 – 326

Takahashi, M, Shimizu, T, Moriizumi, E, and Shirasawa, T Clk-1 deficiency induces apoptosis associated with mitochondrial dysfunction in mouse embryos Mechanisms of Ageing and Development 2008; 129 291 - 298

Jian Chena, Jinmin Zhua, Hyun-Hee Chob, Kemi Cuia, Fuhai Lia, Xiaobo Zhoua, Jack T. Rogersb, Stephen T.C. Wonga, Xudong Huang Differential cytotoxicity of metal oxide nanoparticles Journal of Experimental Nanoscience 2008;Vol. 3, No. 4, December 2008, 321–328

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Zhengyu Pang, James N. Cawse, Liming Yu, William D. Richards Doubly stochastic Poisson distribution of platelet adhesion on material surfaces and its implication on fluorescence image analysis Journal of Biomedical Materials Research Part A 2009;Volume 89A Issue 1, Pages 224 - 232

Janet L Anderl, Stella Redpath, Andrew J Ball A Neuronal and Astrocyte Co-Culture Assay for High Content Analysis of Neurotoxicity Journal of Visualized Experiments 2009; http://www.jove.com/index/Details.stp?ID=1413

Christophe Antczak, Toshimitsu Takagi, Christina N. Ramirez, Constantin Radu, and Hakim Djaballah, Dr. Live-Cell Imaging of Caspase Activation for High-Content Screening Journal of Biomolecular Screening 2009; 14:956.

Aidan G. Gilmartin, Maureen R. Bleam, Mark C. Richter, Symon G. Erskine, Ryan G. Kruger, Lenore Madden, Daniel F. Hassler, Gary K. Smith, Richard R. Gontarek, Mary P. Courtney, David Sutton, Melody A. Diamond, Jeffrey R. Jackson and Sylvie G. Laquerre Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis Cancer Research 69, 6969, September 1, 2009. Lee-Anne B. Rawlinson, Peter J. O'Brien and David J. Brayden High content analysis of cytotoxic effects of pDMAEMA on human intestinal epithelial and monocyte cultures Journal of Controlled Release 2010; 2010 Aug 17;146(1):84-92. Epub 2010 May 10.

Sofie Claerhout, Lien Verschooten, Sofie Van Kelst, Rita De Vos, Charlotte Proby, Patrizia Agostinis and Marjan Garmyn Concomitant inhibition of AKT and autophagy is required for efficient cisplatin-induced apoptosis of metastatic skin carcinoma International International Journal of Cancer 2010; Volume 127, Issue 12, pages 2790–2803, 15 December 2010

Naoko Seki, Uhi Toh, Thomas J. Sayers, Teruhiko Fujii, Motoshi Miyagi, Yoshito Akagi, Jingo Kusukawa, Masayoshi Kage, Kazuo Shirouzu, and Hideaki Yamana Bortezomib Sensitizes Human Esophageal Squamous Cell Carcinoma Cells to TRAIL–Mediated Apoptosis via Activation of Both Extrinsic and Intrinsic Apoptosis Pathways Molecular Cancer Therapeutics 2010; June 2010 9; 1842-1851

Dilyara Arslanova, Ting Yang, Xiaoyin Xu, Stephen T Wong, Corinne E Augelli-Szafran, Weiming Xia Phenotypic analysis of images of zebrafish treated with Alzheimer’s g-secretase inhibitors BMC Biotechnology 2010; 2010, 10:24

Takahide Kaji, Sawako Yoshida, Kunji Kawai, Yoshihiro Fuchigami, Wakako Watanabe, Hideo Kubodera, Toshimitsu Kishimoto ASK3, a novel member of the apoptosis signal-regulating kinase family, is essential for stress-induced cell death in HeLa cells Biochemical and Biophysical Research Communications 2010; 395 (2010) 213–218

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N.T. Lieggi, A. Edvardsson, and P.J. O’Brien Translation of novel anti-cancer cytotoxicity biomarkers detected with high content analysis from an in vitro predictive model to an in vivo cell model Toxicology in Vitro 2010; 2010 Dec;24(8):2063-71

Craig C. Beeson, Gyd C. Beeson and Rick G. Schnellmann A high-throughput respirometric assay for mitochondrial biogenesis and toxicity Analytical Biochemistry 2010; Volume 404, Issue 1, 1 September 2010, Pages 75-81

Daniel C. Gray, Sami Mahrus and James A. Wells Activation of Specific Apoptotic Caspases with an Engineered Small-Molecule-Activated Protease Cell 2010; 142, 637–646, August 20, 2010

Il Sang Yoon, Qingyan Au, Jack R. Barber, Shi Chung Ng, Bin Zhang Development of a high-throughput screening assay for cytoprotective agents in rotenone-induced cell death Analytical Biochemistry 2010; 407 (2010) 205–210

Marjo Götte, a, , Gabriele Hofmann1, a, Anne-Isabelle Michou-Gallani2, a, J. Fraser Glickman3, a, William Wishart4, a and Daniela Gabriel An imaging assay to analyze primary neurons for cellular neurotoxicity Journal of Neuroscience Methods 2010; Volume 192, Issue 1, 30 September 2010, Pages 7-16

FLZ, a novel HSP27 and HSP70 inducer, protects SH-SY5Y cells from apoptosis caused by MPP+ Xiang-chen Kong, Dan Zhang, Cheng Qian, Geng-tao Liu and Xiu-qi Bao Brain Research 2011; 2011 Apr 6;1383:99-107. Epub 2011 Feb 2.

Iron handling in hippocampal neurons: activity-dependent iron entry and mitochondria-mediated neurotoxicity Ilaria Pelizzoni, Romina Macco, Marco Francesco Morini, Daniele Zacchetti, Fabio Grohovaz, Franca Codazzi Aging Cell 2011; Volume 10, Issue 1, pages 172–183, February 2011

Zoulikha M. Zaïr, Gareth J. Jenkins, Shareen H. Doak, Raj Singh, Karen Brown and George E. Johnson N-Methylpurine DNA Glycosylase Plays a Pivotal Role in the Threshold Response of Ethyl Methanesulfonate–Induced Chromosome Damage Toxicological Sciences 2011; (2011) 119 (2): 346-358

Aya Shibai-Ogata, Chihaya Kakinuma, Takanori Hioki and Toshihiko Kasahara Evaluation of high-throughput screening for in vitro micronucleus test using fluorescence-based cell imaging Mutagenesis 2011; First published online: July 10, 2011

Edwin G. Walsh, Sam Maher, Marc Devocelle, Peter J. O’Brien, Alan W. Baird and David J. Brayden High Content Analysis to Determine Cytotoxicity of the Antimicrobial Peptide, Melittin and Selected Structural Analogues Peptides 2011; Volume 32, Issue 8, August 2011, Pages 1764-1773

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Kyoko Shirakabe, Seisuke Hattori, Motoharu Seiki, Shigeo Koyasu, and Yasunori Okada VIP36 IS A TARGET OF ECTODOMAIN SHEDDING AND REGULATES PHAGOCYTOSIS IN MACROPHAGE Raw 264.7 CELLS Journal of Biological Chemistry Papers in Press 2011; Published on October 20, 2011

Bashir M Mohamed1, Navin K Verma, Adriele Prina-Mello, Yvonne Williams, Anthony M Davies, Gabor Bakos, Laragh Tormey, Connla Edwards, John Hanrahan, Anna Salvati, Iseult Lynch, Kenneth Dawson, Dermot Kelleher and Yuri Volkov Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity Journal of Nanobiotechnology 2011; 2011, 9:29

Zhongyuan Zhang Kiichiro Teruya, Hiroshi Eto, Sanetaka Shirahata Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways PLoS ONE 2011; November 2011 | Volume 6 | Issue 11 | e27441

Beat Nyfeler, Philip Bergman, Ellen Triantafellow, Christopher J. Wilson, Yanyi Zhu, Branko Radetich, Peter M. Finan, Daniel J. Klionsky and Leon O. Murphy Relieving Autophagy and 4EBP1 from Rapamycin Resistance Molecular and Cell Biology 2011; July 2011 vol. 31 no. 14 2867-2876

Na Ning, Jin-feng Hu, Yu-he Yuan, Xin-yuan Zhang, Jun-gui Dai and Nai-hong Chen Huperzine A derivative M3 protects PC12 cells against sodium nitroprusside-induced apoptosis Acta Pharmacologica Sinica; 2012 33: 34–40

Reiko Nagano, Hiromi Akanuma, Xian-Yang Qin, Satoshi Imanishi, Hiroyoshi Toyoshiba, Jun Yoshinaga, Seiichiroh Ohsako and Hideko Sone Multi-Parametric Profiling Network Based on Gene Expression and Phenotype Data_A Novel Approach to Developmental Neurotoxicity Testing International Journal of Molecular Sciences; 2012, 13, 187-207

Dania Movia, Adriele Prina-Mello, Despina Bazou, Yuri Volkov and Silvia Giordani Screening the Cytotoxicity of Single-Walled Carbon Nanotubes Using Novel 3D Tissue-Mimetic Models ACS Nano, 2011, 5 (11), pp 9278–9290

Eve Ramery, Peter J. O'Brien Evaluation of the cytotoxicity of organic dust components on THP1 monocytes-derived macrophages using high content analysis Environmental Toxicology 2012; Online First

Xiaoming Hea, Satoshi Imanishia, Hideko Sone, Reiko Nagano, Xian-Yang Qin, Jun Yoshinaga, Hiromi Akanuma, Junko Yamane, Wataru Fujibuchi, Seiichiroh Ohsako Effects of methylmercury exposure on neuronal differentiation of mouse and human embryonic stem cells Toxicology Letters 2012; Volume 212, Issue 1, 7 July 2012, Pages 1–10

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MarioMauthe, Wenqi Yu, Oleg Krut, Martin Kr¨onke, Friedrich G¨otz, Horst Robenek, and Tassula Proikas-Cezanne WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus aureus for Lysosomal Degradation International Journal of Cell Biology 2012; Volume 2012, Article ID 179207, 13 pages

Yuan Wen, Xudong Zhang and Shang-Tian Yang Medium to High Throughput Screening: Microfabrication and Chip-Based Technology Advances in Experimental Medicine and Biology 2012; Volume 745, 181-209

Beat Nyfeler, Philip Bergman, Christopher J. Wilson and Leon O. Murphy Quantitative Visualization of Autophagy Induction by mTOR Inhibitors Methods in Molecular Biology 2012; Volume 821, 239-250

Aya Shibai-Ogata, Haruna Tahara, Yusuke Yamamoto, Masaharu Fujita, Hiroshi Satoh, Atsuko Yuasa, Takanori Hioki, and Toshihiko Kasahara An automated new technique for scoring the in vivo micronucleus assay with image analysis Mutagenesis, Jan 2014; 29: 63 - 71.

Justin D. Boyd, J. Peter Lee-Armandt, Marisa S. Feiler, Nava Zaarur, Min Liu, Brian Kraemer, John B. Concannon, Atsushi Ebata, Benjamin Wolozin, and Marcie A. Glicksman A High-Content Screen Identifies Novel Compounds That Inhibit Stress-Induced TDP-43 Cellular Aggregation and Associated Cytotoxicity J Biomol Screen, Jan 2014; 19: 44 - 56.

Jinfu Xie, Julie Zorman, Lani Indrawati, Melanie Horton, Keri Soring, Joseph M. Antonello, Yuhua Zhang, Susan Secore, Matthew Miezeiewski, Su Wang, Anthony D. Kanavage, Julie M. Skinner, Irene Rogers, Jean-Luc Bodmer, and Jon H. Heinrichs Development and Optimization of a Novel Assay To Measure Neutralizing Antibodies against Clostridium difficile Toxins Clin. Vaccine Immunol., Apr 2013; 20: 517 - 525.

Sandy Eldridge, Liang Guo, Jodie Mussio, Mike Furniss, John Hamre, III, and Myrtle Davis Examining the Protective Role of ErbB2 Modulation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Toxicol. Sci., Oct 2014; 141: 547 - 559.

Mike Clements and Nick Thomas High-Throughput Multi-Parameter Profiling of Electrophysiological Drug Effects in Human Embryonic Stem Cell Derived Cardiomyocytes Using Multi-Electrode Arrays Toxicol. Sci., Aug 2014; 140: 445 - 461.

Metabolism Harada, H and Takahashi, M CD44-dependent Intracellular and Extracellular Catabolism of Hyaluronic Acid by Hyaluronidase-1 and -2 Journal of Biological Chemistry 2007; 282 5597 - 5607

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Yoshiko Fujita, Akemi Kakino1, Norihisa Nishimichi, Saburo Yamaguchi, Yuko Sato, Sachiko Machida, Luciano Cominacini, Yves Delneste, Haruo Matsuda and Tatsuya Sawamura Oxidized LDL Receptor LOX-1 Binds to C-Reactive Protein and Mediates Its Vascular Effects Clinical Chemistry 2009; 55:285-294

Yoshiko Fujita, Akemi Kakino, Mariko Harada-Shiba, Yuko Sato, Kazunori Otsui, Ryo Yoshimoto, Tatsuya Sawamura C-Reactive Protein Uptake by Macrophage Cell Line via Class-A Scavenger Receptor Clinical Chemistry 2010; 56:478-481

2008 Naonobu Nishino, Yoshikazu Tamori, Sanshiro Tateya, Takayuki Kawaguchi, Tetsuro Shibakusa, Wataru Mizunoya, Kazuo Inoue, Riko Kitazawa, Sohei Kitazawa, Yasushi Matsuki, Ryuji Hiramatsu, Satoru Masubuchi, Asako Omachi, Kazuhiro Kimura, Masayuki Saito, Taku Amo, Shigeo Ohta, Tomohiro Yamaguchi, Takashi Osumi, Jinglei Cheng, Toyoshi Fujimoto, Harumi Nakao, Kazuki Nakao, Atsu Aiba, Hitoshi Okamura, Tohru Fushiki, and Masato Kasuga FSP27 contributes to efficient energy storage in murine white adipocytes by promotingthe formation of unilocular lipid droplets The Journal of Clinical Investigation Volume 118 Number 8 August 2008

Shilpi Arora, Christian Beaudry, Kristen M. Bisanz, Chao Sima, Jeffrey A. Kiefer, David O. Azorsa. A High-Content RNAi-Screening Assay to Identify Modulators of Cholesterol Accumulation in Niemann–Pick Type C Cells ASSAY and Drug Development Technologies 2010; June 2010, 8(3): 295-319.

Gavin I. Welsh, Lorna J. Hale, Vera Eremina, Marie Jeansson, Yoshiro Maezawa, Rachel Lennon, Deborah A. Pons, Rachel J. Owen, Simon C. Satchell, Mervyn J. Miles, Christopher J. Caunt, Craig A. McArdle, Hermann Pavensta¨ dt, Jeremy M. Tavare´, Andrew M. Herzenberg, C. Ronald Kahn, Peter W. Mathieson, Susan E. Quaggin, Moin A. Saleem and Richard J.M. Coward Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function Cell Metabolism 2010; 12, 329–340, October 6, 2010

Kazunori Otsui, Makoto Kakutani, Koji Yuasa, Atushi Nakano, Chang-Ping Hu, Akemi Kakino, Yuko Sato, Yoshiko Fujita, Yosuke Kawase, Kou-ichi Jishage, Hiroshi Suzuki, Jawahar L. Mehta, Mitsuhiro Yokoyama, Ken-ichi Hirata, Nobutaka Inoue and Tatsuya Sawamura Calcium-dependent platelet aggregation through the interaction between phosphatidylserine and LOX-1 Cardiovascular Research 2010; (2010) 88 (3): 547.

Taichi NISHIZUKA, Yoshiko FUJITA, Yuko SATO, Atushi NAKANO, Akemi KAKINO, Shunji OHSHIMA, Tomomasa KANDA, Ryo YOSHIMOTO and Tatsuya SAWAMURA Procyanidins are potent inhibitors of LOX-1: a new player in the French Paradox Proceedings of the Japan Academy. Series B, Physical and Biological Sciences 2011; March 11;

87(3): 104–113 Jong Bae Seo, Sung Sik Choe, Hyun Woo Jeong, Sang Wook Park, Hyun Jung Shin, Sun Mi Choi, Jae Young Park, Eun Wook Choi, Jae Bum Kim, Dong Seung Seen, Jae-Yeon Jeong, and Tae Gyu Lee Anti-obesity effects of Lysimachia foenum-graecum characterized by decreased adipogenesis and regulated lipid metabolism Experimental & Molecular Medicine 2011; April 30; 43(4): 205–215.

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Reiko Ishitsuka, Tamio Saito, Hiroyuki Osada, Yoshiko Ohno-Iwashita, and Toshihide Kobayashi Fluorescence image screening for chemical compounds modifying cholesterol metabolism and distribution Journal of Lipid Research 2011; Volume 52, 2011

Yoshiko Fujita, Saburo Yamaguchi, Akemi Kakino, Shin Iwamoto, Ryo Yoshimoto and Tatsuya Sawamura Lectin-like Oxidized LDL Receptor 1 Is Involved in CRP-Mediated Complement Activation Clinical Chemistry 2011; 57: 1398-1405, 2011

Yu Zhang, Haitao Zhang, Xin-gang Yao, Hong Shen, Jing Chen1, Chenjing Li, Lili Chen, Mingyue Zheng, Jiming Ye, Lihong Hu, Xu Shen1, Hualiang Jiang (+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice PLoS ONE 2012; February 2012 | Volume 7 | Issue 2 | e31811

Kumiko Ishii, Tamio Saito, Hiroyuki Osada, Naoyuki Taniguchi, Tadashi Suzuki Identification of compounds that augment the lectin-sensitivity of Chinese Hamster Ovary cells Biochemical and Biophysical Research Communications 2012; Volume 423, Issue 2, 29 June 2012,

Pages 429–435 Akimitsu Konishi, Satoko Arakawa, Zhenyu Yue and Shigeomi Shimizu Involvement of Beclin 1 in the engulfment of apoptotic cells The Journal of Biological Chemistry 2012; Online First

Françoise Hullin-Matsuda, Nario Tomishige, Shota Sakai, Reiko Ishitsuka, Kumiko Ishii, Asami Makino, Peter Greimel, Mitsuhiro Abe, Elad L. Laviad, Michel Lagarde, Hubert Vidal, Tamio Saito, Hiroyuki Osada, Kentaro Hanada, Anthony H. Futerman and Toshihide Kobayashi Limonoid Compounds Inhibit Sphingomyelin Biosynthesis by Preventing CERT Protein-dependent Extraction of Ceramides from the Endoplasmic The Journal of Biological Chemistry 2012; 287, 24397-24411.

Gaelle Boncompain, Severine Divoux, Nelly Gareil, Helene de Forges, Aurianne Lescure, Lynda Latreche, Valentina Mercanti, Florence Jollivet, Graça Raposo & Franck Perez Synchronization of secretory protein traffic in populations of cells Nature Methods 2012; Volume:9, Pages:493–498

Miao Xu, Ke Liu, Manju Swaroop, Wei Sun, Seameen J. Dehdashti, John C. McKew, and Wei Zheng A Phenotypic Compound Screening Assay for Lysosomal Storage Diseases J Biomol Screen, Jan 2014; 19: 168 - 175.

Li Wang, Xiao-Jian Jia, Hua-Jun Jiang, Yu Du, Fan Yang, Shu-Yi Si, and Bin Hong MicroRNAs 185, 96, and 223 Repress Selective High-Density Lipoprotein Cholesterol Uptake through Posttranscriptional Inhibition Mol. Cell. Biol., May 2013; 33: 1956 - 1964.

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Akihiro Shimomura, Isao Matsui, Takayuki Hamano, Takuya Ishimoto, Yumiko Katou, Kenji Takehana, Kazunori Inoue, Yasuo Kusunoki, Daisuke Mori, Chikako Nakano, Yoshitsugu Obi, Naohiko Fujii, Yoshitsugu Takabatake, Takayoshi Nakano, Yoshiharu Tsubakihara, Yoshitaka Isaka, and Hiromi Rakugi Dietary L-Lysine Prevents Arterial Calcification in Adenine-Induced Uremic Rats J. Am. Soc. Nephrol., Sep 2014; 25: 1954 - 1965.

Simon G. Pfisterer, Daniela Bakula, Tancred Frickey, Alice Cezanne, Daniel Brigger, Mario P. Tschan, Horst Robenek, and Tassula Proikas-Cezanne Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells J. Lipid Res., Jul 2014; 55: 1267 - 1278.

Takaharu Hayashi, Yoshihiro Asano, Yasunori Shintani, Hiroshi Aoyama, Hidetaka Kioka, Osamu Tsukamoto, Masahide Hikita, Kyoko Shinzawa-Itoh, Kazuaki Takafuji, Shuichiro Higo, Hisakazu Kato, Satoru Yamazaki, Ken Matsuoka, Atsushi Nakano, Hiroshi Asanuma, Masanori Asakura, Tetsuo Minamino, Yu-ichi Goto, Takashi Ogura, Masafumi Kitakaze, Issei Komuro, Yasushi Sakata, Tomitake Tsukihara, Shinya Yoshikawa, and Seiji Takashima Higd1a is a positive regulator of cytochrome c oxidase PNAS, Feb 2015; 112: 1553 - 1558.

Anas M Abdel Rahman, Michael Ryczko, Miyako Nakano, Judy Pawling, Tania Rodrigues, Anita Johswich, Naoyuki Taniguchi, and James W Dennis Golgi N-glycan branching N-acetylglucosaminyltransferases I, V and VI promote nutrient uptake and metabolism Glycobiology, Feb 2015; 25: 225 - 240.

Daozhan Yu, Manju Swaroop, Mengqiao Wang, Ulrich Baxa, Rongze Yang, Yiping Yan, Turhan Coksaygan, Louis DeTolla, Juan J. Marugan, Christopher P. Austin, John C. McKew, Da-Wei Gong, and Wei Zheng Niemann–Pick Disease Type C: Induced Pluripotent Stem Cell–Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy J Biomol Screen, Sep 2014; 19: 1164 - 1173.

Virology (including Infectious disease) Masaharu Takahashi, Kentaro Yamada, Yu Hoshino, Hideyuki Takahashi, Koji Ichiyama, Toshinori Tanaka, Hiroaki Okamoto Monoclonal antibodies raised against the ORF3 protein of hepatitis E virus (HEV) can capture HEV particles in culture supernatant and serum but not those in feces Arch Virol 2008; 153:1703–1713

Jason Borawski, Philip Troke, Xiaoling Puyang, Veronica Gibaja, ShanChaun Zhao, Craig Mickanin, Juliet Leighton-Davies, Christopher J. Wilson, Vic Myer, Ivan CornellaTaracido, Jeremy Baryza, John Tallarico, Gerard Joberty, Marcus Bantscheff, Markus Schirle, Tewis Bouwmeester, Joanna E. Mathy, Kai Lin, Teresa Compton, Mark Labow, Brigitte Wiedmann, and L. Alex Gaither Class III phosphatidylinositol-4 kinase alpha & beta are novel host factor regulators of hepatitis C virus replication Journal of Virology 2009; 2009 Oct;83(19):10058-74

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Jianqi Wanga, Naoyuki Kondo, Yufei Longa, Aikichi Iwamotob, and Zene Matsuda Monitoring of HIV-1 envelope-mediated membrane fusion using modified split green fluorescent proteins Journal of Virological Methods 2009; Volume 161, Issue 2, November 2009, Pages 216-222

Juan C. Engel, Kenny K.H. Ang, Steven Chen, Michelle R. Arkin, James H. McKerrow and Patricia S. Doyle Image-Based High Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2010; Aug. 2010, p. 3326–3334

Kondo N, Miyauchi K, Meng F, Iwamoto A, Matsuda Z. Conformational Changes of the HIV-1 Envelope Protein during Membrane Fusion Are Inhibited by the Replacement of Its Membrane-spanning Domain Journal of Biological Chemistry 2010; May 7;285(19):14681-8

David Shum, Jessica L. Smith, Alec J. Hirsch, Bhavneet Bhinder, Constantin Radu, David A. Stein, Jay A. Nelson, Klaus Früh and Hakim Djaballah High-Content Assay to Identify Inhibitors of Dengue Virus Infection Technologies 2010; October 2010, 8(5): 553-570

An image-based assay for high throughput screening of Giardia lamblia Jiri Gut, Kenny K.H. Ang, Jennifer Legac, Michelle R. Arkinb, Philip J. Rosenthal and James H. McKerrow Journal of Microbiological Methods 2011; Volume 84, Issue 3, March 2011, Pages 398-405

High-content screening to distinguish between attachment and post-attachment steps of human cytomegalovirus entry into fibroblasts and epithelial cells Yvonne Ibig-Rehma, Marjo Götte, Daniela Gabriel, David Woodhall, Ashley Shea, Nathan E. Brown, Teresa Compton and Adam L. Feire Antiviral Research 2011; Volume 89, Issue 3, March 2011, Pages 246-256

Agonist-induced internalization of CCR5 as a mechanism to inhibit HIV replication Thierry Ferain, Hamid Hoveyda, Frédéric Ooms, Dominique Schols, Jérôme Bernard and Graeme Fraser The Journal of Pharmacology and Experimental Therapeutics 2011; Accepted March 8, 2011

Kenny K. H. Ang, Joseline Ratnam, Jiri Gut, Jennifer Legac, Elizabeth Hansell, Zachary B. Mackey, Katarzyna M. Skrzypczynska, Anjan Debnath, Juan C. Engel, Philip J. Rosenthal, James H. McKerrow, Michelle R. Arkin, Adam R. Renslo Mining a Cathepsin Inhibitor Library for New Antiparasitic Drug Leads PLOS 2011; May 2011 Volume 5 Issue 5 e1023

Y.X. Setoh, J. Hobson-Peters, N.A. Prow, P.R. Young, R.A. Hall Expression of recombinant West Nile virus prM protein fused to an affinity tag for use as a diagnostic antigen Journal of Virological Methods 2011; 175 (2011) 20– 27

Geraldine De Muylder, Kenny K. H. Ang, Steven Chen, Michelle R. Arkin, Juan C. Engel, James H. McKerrow A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit PLOS 2011; July 2011 Volume 5 Issue 7 e1253

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Ruth CM Ryan, Mary P O'Sullivan, Joseph Keane Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells BMC Microbiology 2011; 2011, 11:237

Deepa Srikanta, Meng Yang, Matthew Williams, Tamara L. Doering A Sensitive High-Throughput Assay for Evaluating Host-Pathogen Interactions in Cryptococcus neoformans Infection PLoS ONE 2011; July 2011 Volume 6 Issue 7 e22773

Francesca Graziano, Chiara Elia, Carlo Laudanna, Guido Poli, Massimo Alfano Urokinase Plasminogen Activator Inhibits HIV Virion Release from Macrophage-Differentiated Chronically Infected Cells via Activation of RhoA and PKCε PLoS ONE 2011; August 2011 Volume 6 Issue 8 e23674

Yufei Long, Fanxia Meng, Naoyuki Kondo, Aikichi Iwamoto and Zene Matsuda Conserved arginine residue in the membrane-spanning domain of HIV-1 gp41 is required for efficient membrane fusion Protein & Cell 2011; Volume 2, Number 5, 369-376,

Nicola Clementi, Donata De Marco, Nicasio Mancini, Laura Solforosi, Guisella J. Moreno, Larisa V. Gubareva, Vasiliy Mishin, Andrea Di Pietro, Elisa Vicenzi, Antonio G. Siccardi, Massimo Clementi, Roberto Burioni A Human Monoclonal Antibody with Neutralizing Activity against Highly Divergent Influenza Subtypes PLoS ONE 2011; December 2011 | Volume 6 | Issue 12 | e28001

Shamila S. Gunatilleke, Claudia M. Calvet, Jonathan B. Johnston, Chiung-Kuang Chen, Grigori Erenburg, Jiri Gut, Juan C. Engel, Kenny K. H. Ang, Joseph Mulvaney, Steven Chen, Michelle R. Arkin, James H. McKerrow, Larissa M. Podust Diverse Inhibitor Chemotypes Targeting Trypanosoma cruzi CYP51 PLoS 2012; July 2012 | Volume 6 | Issue 7 | e1736

Fahad N. Almajhdi, Mohamed S. Alshaman, Haitham M. Amer Molecular characterization and phylogenetic analysis of human parainfluenza virus type 3 isolated from Saudi Arabia Journal of Medical Virology 2012; Volume 84, Issue 8, pages 1304–1311, August 2012

Donata De Marco, Nicola Clementi, Nicasio Mancini, Laura Solforosi, Guisella J. Moreno, Xiangjie Sun, Terrence M. Tumpey, Larisa V. Gubareva, Vasiliy Mishin, Massimo Clementi, Roberto Burioni A Non-VH1-69 Heterosubtypic Neutralizing Human Monoclonal Antibody Protects Mice against H1N1 and H5N1 Viruses PLos ONE 2012; April 2012 | Volume 7 | Issue 4 | e34415

Stephen H.-F. Macdonald, Elliott Woodward, Michelle M. Coleman, Emma R. Dorris, Parthiban Nadarajan, Wui-Mei Chew, Anne-Marie McLaughlin, Joseph Keane Networked T Cell Death following Macrophage Infection by Mycobacterium tuberculosis PLoS ONE 2012; June 2012 | Volume 7 | Issue 6 | e38488

Junki Maruyama, Hiroko Miyamoto, Masahiro Kajihara, Hirohito Ogawa, Ken Maeda, Yoshihiro Sakoda, Reiko Yoshida, and Ayato Takada Characterization of the Envelope Glycoprotein of a Novel Filovirus, Lloviu Virus J. Virol., Jan 2014; 88: 99 - 109.

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Stem Cell (including Differentiation) Hideki Kato, Junji Ishida, Katsumasa Nagano, Kaori Honjo, Takeshi Sugaya, Norifumi Takeda, Fumihiro Sugiyama, Ken-ichi Yagami, Toshiro Fujita, Masaomi Nangaku and Akiyoshi Fukamizu Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells Laboratory Investigation 2008; 88, 731–739

NEIL J. HARRISON, JAMES BARNES, MARK JONES, DUNCAN BAKER, PAUL J. GOKHALE, PETER W. ANDREWS CD30 Expression Reveals that Culture Adaptation of Human Embryonic Stem Cells Can Occur Through Differing Routes STEM CELLS 2009;27:1057–10651

Leon R. McQuade, Uli Schmidt, Dana Pascovici, Tomas Stojanov and Mark S. Baker Improved Membrane Proteomics Coverage of Human Embryonic Stem Cells by Peptide IPG-IEF Journal of Proteome Research, 2009; 8 (12), pp 5642–5649

Senescence impairs successful reprogramming to pluripotent stem cells Ana Banito, Sheikh T. Rashid, Juan Carlos Acosta, SiDe Li, Carlos F. Pereira, Imbisaat Geti, Sandra Pinho, Jose C. Silva, Veronique Azuara, MartinWalsh, Ludovic Vallier, and Jesu´s Gil Genes & Development 2009; 23: 2134-2139 Cara K. Bradley, Omar Chami, Teija T. Peura, Alexis Bosman, Biljana Dumevska, Uli Schmidt, Tomas Stojanov Derivation of three new human embryonic stem cell lines In Vitro Cellular & Developmental Biology - Animal, 2010; 46:294–299 De Palma, S Falcone, S Pisoni, S Cipolat, C Panzeri, S Pambianco, A Pisconti, R Allevi, MT Bassi, GCossu,T Pozzan, S Moncada, L Scorrano, S Brunelli, and E Clementi Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation Cell Death and Differentiation 2010, 1–13

Nathan Salomonis, Christopher R. Schlieve, Laura Pereira, Christine Wahlquist, Alexandre Colas, Alexander C. Zambon, Karen Vranizan, Matthew J. Spindler, Alexander R. Pico, Melissa S. Cline, Tyson A. Clark, Alan Williams, John E. Blume, Eva Samal, Mark Mercola, Bradley J. Merrill, and Bruce R. Conklin Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation PNAS 2010; June 8, 2010 vol. 107 no. 23 10514–10519

Payman Samavarchi-Tehrani, Azadeh Golipour, Laurent David, Hoon-ki Sung, Tobias A. Beyer, Alessandro Datti, Knut Woltjen2, Andras Nagy, and Jeffrey L. Wrana Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming Cell Stem Cell 2010, Volume 7, Issue 1, 64-77, 17 June 2010

Silvia Cainarca, Simone Fenu, Silvia Bovolenta, Patrizia Arioli, Andrea Menegon, Stefan Lohmer, Sabrina Corazza From c-Photina® Mouse Embryonic Stem Cells to High-Throughput Screening of Differentiated Neural Cells via an Intermediate Step Enriched in Neural Precursor Cells Journal of Biomolecular Screening 2010; 2010 Oct;15(9):1132-43. Epub 2010 Sep 10.

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A Gambardella, C.K. Nagaraju, P.J. O'Shea, S.T. Mohanty, L. Kottam, J. Pilling, M. Sullivan, M. Djerbi, W. Koopmann, P.I. Croucher, I. Bellantuono Glycogen synthase kinase-3/β inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage Journal of Bone and Mineral Research 2010; 2010 Oct 11. [Epub ahead of print]

Satoshi Kawase, Takao Imai, Chikako Miyauchi-Hara, Kunio Yaguchi, Yoshinori Nishimoto, Shin-ichi Fukami, Yumi Matsuzaki, Atsushi Miyawaki, Shigeyoshi Itohara, and Hideyuki Okano Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells Molecular Brain 2011; 4: 14.

Andrews PD, Becroft M, Aspegren A, Gilmour J, James MJ, McRae S, Kime R, Allcock RW, Abraham A, Jiang Z, Strehl R, Mountford JC, Milligan G, Houslay MD, Adams DR, Frearson JA. High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules Biochemical Journal 2010; 2010 Oct 25; 432(1):21-33.

Ivana Barbaric, Paul J. Gokhale, Mark Jones, Adam Glen, Duncan Baker and Peter W. Andrews Novel regulators of stem cell fates identified by a multivariate phenotype screen of small compounds on human embryonic stem cell colonies Stem Cell Research 2010; Volume 5, Issue 2, September 2010, Pages 104-119

Alberto Yáñez, Ana Flores, Celia Murciano, José-Enrique O'Connor, Daniel Gozalbo, M. Luisa Gil Signalling through TLR2/MyD88 induces differentiation of murine bone marrow stem and progenitor cells to functional phagocytes in response to Candida albicans Cellular Microbiology 2010; Volume 12, Issue 1, pages 114–128, January 2010

Alberto Yáñez Ana Flores Celia Murciano José-Enrique O’Connor Daniel Gozalbo and M. Luisa Gil Signalling through TLR2/MyD88 induces differentiation of murine bone marrow stem and progenitor cells to functional phagocytes in response to Candida albicans Cellular Microbiology (2010) 12(1), 114–128

Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells O Cordero-Llana, S A Scott, S L Maslen, J M Anderson, J Boyle, R-R Chowhdury, P Tyers, R A Barker, C M Kelly, A E Rosser, E Stephens, S Chandran and M A Caldwell Cell Death & Differentiation 2011; 7 January 2011

Growth factor-defined culture medium for human mesenchymal stem cells SUMIYO MIMURA, NAOHIRO KIMURA, MITSUHI HIRATA, DAIKI TATEYAMA, MIDORI HAYASHIDA, AKIHIRO UMEZAWA, ARIHIRO KOHARA, HIROKI NIKAWA, TETSUJI OKAMOTO and MIHO K. FURUE The International Journal of Developmental Biology 2011; 55: 181-187 (2011)

Denise K. Marciano, Paul R. Brakeman, Chao-Zong Lee, Natalie Spivak, Dennis J. Eastburn, David M. Bryant, Gerard M. Beaudoin III, Ilse Hofmann, Keith E. Mostov and Louis F. Reichardt p120 catenin is required for normal renal tubulogenesis and glomerulogenesis Development 2011; 138, 2099-2109.

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Sandra U Schmitz, Mareike Albert, Martina Malatesta, Lluis Morey, Jens V Johansen, Mads Bak, Niels Tommerup, Iratxe Abarrategui, and Kristian Helin Jarid1b targets genes regulating development and is involved in neural differentiation The EMBO Journal 2011; (2011), 1–15

Yuya Kunisada, Noriko Tsubooka-Yamazoe, Masanobu Shoji, Masaki Hosoya, Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells Stem Cell Research 2012; Volume 8, Issue 2, March 2012, Pages 274–284

Ivana Barbaric, Mark Jones, Kristina Buchner, Duncan Baker, Peter W. Andrews, Harry D. Moore Pinacidil enhances survival of cryopreserved human embryonic stem cells Cryobiology 2011; In Press, Corrected Proof

Ivana Barbaric, Mark Jones, David J. Harley, Paul J. Gokhale, Peter W. Andrews High-Content Screening for Chemical Modulators of Embryonal Carcinoma Cell Differentiation and Survival Journal of Biomolecular Screening 2011; July 2011 vol. 16 no. 6 603-617

Michela Vezzoli, Patrizia Castellani, Gianfranca Corna, Alessandra Castiglioni, Lidia Bosurgi, Antonella Monno, Silvia Brunelli, Angelo A. Manfredi, Anna Rubartelli, and Patrizia Rovere-Querini High-Mobility Group Box 1 Release and Redox Regulation Accompany Regeneration and Remodeling of Skeletal Muscle Antioxidants & Redox Signaling; 2011 October 2011, Vol. 15, No. 8: 2161-2174

K. Sekine, T. Takebe, Y. Suzuki, A. Kamiya, H. Nakauchi, H. Taniguchi Highly Efficient Generation of Definitive Endoderm Lineage from Human Induced Pluripotent Stem Cells Transplantation Proceedings 2012; Volume 44, Issue 4, May 2012, Pages 1127–1129

Fabian Birzele, Sybille Fässler, Heike Neubauer, Tobias Hildebrandt and Bradford S. Hamilton Analysis of the transcriptome of differentiating and non-differentiating preadipocytes from rats and humans by next generation sequencing Molecular and Cellular Biochemistry 2012; Online First

Anne Kümmel, Paul Selzer, Daniela Siebert, Isabel Schmidt, Jürgen Reinhardt, Marjo Götte, Yvonne Ibig-Rehm, Christian N. Parker, Daniela Gabriel Differentiation and Visualization of Diverse Cellular Phenotypic Responses in Primary High-Content Screening Journal of Biomolecular Screening 2012; July 2012 17: 843-849

Tadahiro Shinozawa, Hatsue Furukawa, Eimei Sato, Kenji Takami A Novel Purification Method of Murine Embryonic Stem Cell–and Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes by Simple Manual Dissociation Journal of Biomoleclur Screening 2012; Online First

Mee-Hae Kim, Rie Sonoi, Kenta Yamada, Masakazu Inamori, Masahiro Kino-oka Analysis of locality of early-stage maturation in confluent state of human retinal pigment epithelial cells Journal of Bioscience and Bioengineering 2012; Volume 113, Issue 6, June 2012, Pages 778–781

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Yuichiro Miyaoka, Kazuki Ebato, Hidenori Kato, Satoko Arakawa, Shigeomi Shimizu, Atsushi Miyajima Hypertrophy and Unconventional Cell Division of Hepatocytes Underlie Liver Regeneration Current Biology 2012; Volume 22, Issue 13, 10 July 2012, Pages 1166–1175

Takashi Iwai, Akiyoshi Saitoh, Misa Yamada, Kou Takahashi, Eri Hashimoto, Wataru Ukai, Toshikazu Saito, Mitsuhiko Yamada Rhotekin modulates differentiation of cultured neural stem cells to neurons Journal of Neuroscience Research Volume 90, Issue 7, pages 1359–1366, July 2012

Carmen Escobedo-Lucea, Angel Ayuso-Sacido, Chen Xiong, Sonia Prado-López, Manuel Sanchez del Pino, Dario Melguizo, Carmen Bellver-Estellés, Susana Gonzalez-Granero, M. Luz Valero, Rubén Moreno, Deborah J. Burks & Miodrag Stojkovic Development of a Human Extracellular Matrix for Applications Related with Stem Cells and Tissue Engineering Stem Cell Rev and Rep 2012; 8:170–183

Ana O'Loghlen, Ana M. Muñoz-Cabello, Alexandre Gaspar-Maia, Hsan-Au Wu, Ana Banito, Natalia Kunowska, Tomas Racek, Helen N. Pemberton, Patrizia Beolchi, Fabrice Lavial, Osamu Masui, Michiel Vermeulen, Thomas Carroll, Johannes Graumann, Edith Heard, Niall Dillon, Veronique Azuara, Ambrosius P. Snijders, Gordon Peters, Emily Bernstein, and Jesus Gil MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell 2012; January 6; 10(1-5): 33–46.

Wan Xing Hong, Steven Chen, Jon Akutagawa, Michelle Arkin, and Benjamin S. Braun An In Vitro Library Screen to Rapidly Determine Activity Against Normal and Mutant Bone Marrow Progenitor Cells Blood (ASH Annual Meeting Abstracts), Nov 2012; 120: 4916.

Pei-Cih Wei, Angel Chao, Hsiu-Huei Peng, An-Shine Chao, Yao-Lung Chang, Shuenn-Dyh Chang, Hsin-Shih Wang, Yu-Jen Chang, Ming-Song Tsai, Martin Sieber, Hua-Chien Chen, Shu-Jen Chen, Yun-Shien Lee, Shiaw-Min Hwang, and Tzu-Hao Wang SOX9 as a Predictor for Neurogenesis Potentiality of Amniotic Fluid Stem Cells Stem Cells Trans Med, Oct 2014; 3: 1138 - 1147.

Thomas Xavier Garcia, Jaspreet Kaur Farmaha, Sean Kow, and Marie-Claude Hofmann RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche Development, Dec 2014; 141: 4468 - 4478.

Jianliang Li, Christelle Cousin, Hayley Tinkler, Jawida Touhami, Vincent Petit, and Nick Thomas Profiling of Nutrient Transporter Expression in Human Stem Cell–Derived Cardiomyocytes Exposed to Tyrosine Kinase Inhibitor Anticancer Drugs Using RBD Ligands J Biomol Screen, Sep 2014; 19: 1185 - 1192.

Mara Fornaro, Aaron C. Hinken, Saul Needle, Erding Hu, Anne-Ulrike Trendelenburg, Angelika Mayer, Antonia Rosenstiel, Calvin Chang, Viktor Meier, Andrew N. Billin, J. David Becherer, Arthur D. Brace, William J. Evans, David J. Glass, and Alan J. Russell Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells Am J Physiol Endocrinol Metab, Jan 2014; 306: E150 - E156.

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Hinako M. Takase, Tohru Itoh, Seitaro Ino, Ting Wang, Takehiko Koji, Shizuo Akira, Yasuhiro Takikawa, and Atsushi Miyajima FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration Genes & Dev., Jan 2013; 27: 169 - 181.

Keiko Kawabe, Daiki Tateyama, Hidenao Toyoda, Nana Kawasaki, Noritaka Hashii, Hiromi Nakao, Shogo Matsumoto, Motohiro Nonaka, Hiroko Matsumura, Yoshinori Hirose, Ayaha Morita, Madoka Katayama, Makoto Sakuma, Nobuko Kawasaki, Miho Kusuda Furue, and Toshisuke Kawasaki A novel antibody for human induced pluripotent stem cells and embryonic stem cells recognizes a type of keratan sulfate lacking oversulfated structures Glycobiology, Mar 2013; 23: 322 - 336.

Miriam Gubernator, Sadie C. Slater, Helen L. Spencer, Inmaculada Spiteri, Andrea Sottoriva, Federica Riu, Jonathan Rowlinson, Elisa Avolio, Rajesh Katare, Giuseppe Mangialardi, Atsuhiko Oikawa, Carlotta Reni, Paola Campagnolo, Gaia Spinetti, Anestis Touloumis, Simon Tavaré, Francesca Prandi, Maurizio Pesce, Manuela Hofner, Vierlinger Klemens, Costanza Emanueli, Gianni Angelini, and Paolo Madeddu Epigenetic Profile of Human Adventitial Progenitor Cells Correlates With Therapeutic Outcomes in a Mouse Model of Limb Ischemia Arterioscler Thromb Vasc Biol, Mar 2015; 35: 675 - 688.

Archana Shenoy, Muhammad Danial, and Robert H Blelloch Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis EMBO J., Feb 2015; 10.15252/embj.201489504.

Yuen Kuen Cheong, Zi Xian Ngoh, Gary Swee Lim Peh, Heng-Pei Ang, Xin-Yi Seah, Zhenzhi Chng, Alan Colman, Jodhbir S. Mehta, and William Sun Identification of Cell Surface Markers Glypican-4 and CD200 That Differentiate Human Corneal Endothelium From Stromal Fibroblasts Invest. Ophthalmol. Vis. Sci., Jul 2013; 54: 4538 - 4547.

Tingxia Guo, Limor Landsman, Na Li, and Matthias Hebrok Factors Expressed by Murine Embryonic Pancreatic Mesenchyme Enhance Generation of Insulin-Producing Cells From hESCs Diabetes, May 2013; 62: 1581 - 1592.

Alexandre R. Colas, Wesley L. McKeithan, Thomas J. Cunningham, Paul J. Bushway, Lana X. Garmire, Gregg Duester, Shankar Subramaniam, and Mark Mercola Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis Genes & Dev., Dec 2012; 26: 2567 - 2579.

Pei-Cih Wei, Angel Chao, Hsiu-Huei Peng, An-Shine Chao, Yao-Lung Chang, Shuenn-Dyh Chang, Hsin-Shih Wang, Yu-Jen Chang, Ming-Song Tsai, Martin Sieber, Hua-Chien Chen, Shu-Jen Chen, Yun-Shien Lee, Shiaw-Min Hwang, and Tzu-Hao Wang SOX9 as a Predictor for Neurogenesis Potentiality of Amniotic Fluid Stem Cells Stem Cells Trans Med, Oct 2014; 3: 1138 - 1147.

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A Brief Exposure to Tryptase or Thrombin Potentiates Fibrocyte Differentiation in the Presence of Serum or Serum Amyloid P Michael J. V. White, Elkin Galvis-Carvajal, and Richard H. Gomer J. Immunol., Jan 2015; 194: 142 - 150.

Donna McLaren, Thorsten Gorba, Anita Marguerie de Rotrou, Gopalan Pillai, Clare Chappell, Alison Stacey, Sarah Lingard, Anna Falk, Austin Smith, Philipp Koch, Oliver Brüstle, Richard Vickers, Jon Tinsley, David Flanders, Paul Bello, and Stewart Craig Automated Large-Scale Culture and Medium-Throughput Chemical Screen for Modulators of Proliferation and Viability of Human Induced Pluripotent Stem Cell–Derived Neuroepithelial-like Stem Cells J Biomol Screen, Mar 2013; 18: 258 - 268.

Miscellaneous Allison, K The First Automated High Content Screening System Journal of the Association for Laboratory Automation 2003; 8 27 – 29

Zemanova, Lenka, Schenk, Andreas, Valler, Martin J., Nienhaus, G. Ulrich, and Heilker, Ralf Confocal optics microscopy for biochemical and cellular high-throughput screening Drug Discovery Today 2003; 8 1085 – 1093

Carpenter, Anne E. and Sabatini, David M. Systematic genome-wide screens of gene function Nat Rev Genet 2004; 5 11 – 22

BERND JAGLA, NATHALIE AULNER, PETER D. KELLY, DA SONG, ALLEN VOLCHUK, ANDRZEJ ZATORSKI, DAVID SHUM, THOMAS MAYER, DINO A. DE ANGELIS, OUATHEK OUERFELLI, URS RUTISHAUSER, and JAMES E. ROTHMAN Sequence characteristics of functional siRNAs RNA 2005; 11: 864-872

Nienhaus, G. U., Nienhaus, K., Holzle, A., Ivanchenko, S., Renzi, F., Oswald, F., Wolff, M., Schmitt, F., Rocker, C., Vallone, B., Weidemann, W., Heilker, R., Nar, H., and Wiedenmann, J. Photoconvertible fluorescent protein EosFP: biophysical properties and cell biology applications Photochem.Photobiol. 2006; 82 351 – 358

Wiedenmann, J and Nienhaus, G. U. Live-cell imaging with EosFP and other photoactivatable marker proteins of the GFP family Expert Review in Proteomics 2006; 3 361 – 374

Won, Jaejoon, Kim, Mina, Kim, Nuri, Ahn, Jin Hee, Lee, Woo Gil, Kim, Sung Soo, Chang, Ki Young, Yi, Yong Weon, and Kim, Tae Kook Small molecule-based reversible reprogramming of cellular lifespan Nat Chem Biol 2006; 2 369 – 374

Lin, C, Mak, W, Hong, P, Sepp, K, and Perrimon, N Intelligent Interfaces for Mining Large-Scale RNAi-HCS Image Databases Bioinformatics and Bioengineering, 2007.BIBE 2007.Proceedings of the 7th IEEE International Conference on 2007; 1333 – 1337

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Kin-Chong Lau and Ching-Wan Lam Automated imaging of circulating fluorocytes for the diagnosis of erythropoietic protoporphyria: a pilot study for population screening Journal of Medical Screening 2008; 15:199-203

Zhengyu Pang, James N. Cawse, Liming Yu, William D. Richards Doubly stochastic Poisson distribution of platelet adhesion on material surfaces and its implication on fluorescence image analysis Journal of Biomedical Materials Research Part A 2009; Volume 89A Issue 1, Pages 224 - 232

Yuriy Alexandrov, Albert Francis Santos, Cath Hather, Alla Borisovna Zaltsman Microscopy-Based HTS Examines the Mechanism of Stress F-Actin Fiber Disruption by Cytochalasin D: Orientation Texture Data Collated With Quantitative Kinetic Modeling ASSAY and Drug Development Technologies. 2009; August 2009, 7(4): 366-373.

Keiji Itaka, Kensuke Osada, Katsue Morii, Pilhan Kim, Seok-Hyun Yun and Kazunori Kataoka Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle Journal of Controlled Release 2010; Volume 143, Issue 1, 2 April 2010, Pages 112-119

Jean-Christophe Baret1, Yannick Beck, Isabelle Billas-Massobrio, Dino Moras and Andrew D. Griffiths Quantitative Cell-Based Reporter Gene Assays Using Droplet-Based Microfluidics Chemistry & Biology 2010; Volume 17, Issue 5, 528-536, 28 May 2010

Biraja C. Dash, Gildas Réthoré, Michael Monaghan, Kathleen Fitzgerald, William Gallagher and Abhay Pandit The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility Biomaterials 2010; Volume 31, Issue 32, November 2010, Pages 8188-8197

Dirk Padfield, Jens Rittscher and Badrinath Roysam Coupled minimum-cost flow cell tracking for high-throughput quantitative analysis Medical Image Analysis 2010; 2011 Aug;15(4):650-68. Epub 2010 Aug 13.

Paul J. Bushway, Behrad Azimi, Susanne Heynen-Genel, Jeffrey H. Price, Mark Mercola Hybrid Median Filter Background Estimator for Correcting Distortions in Microtiter Plate Data ASSAY and Drug Development Technologies 2010; April 2010, 8(2): 238-250.

Helge C. Dorfmueller, Vladimir S. Borodkin, Marianne Schimpl, Xiaowei Zheng, Robert Kime, Kevin D. Read and Daan M.F. van Aalten Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal Hexosaminidases Chemistry & Biology 2010; Volume 17, Issue 11, 1250-1255, 24 November 2010

Ching-Wan Lam, Kin-Chong Lau, Chloe Miu Mak, Man-Wo Tsang and Yan-Wo Chan Circulating fluorocytes at the first attack of acute intermittent porphyria: A missing link in the pathogenesis Clinica Chimica Acta 2011; 2011 Jan 14;412(1-2):208-12

FLIM FRET Technology for Drug Discovery: Automated Multiwell-Plate High-Content Analysis, Multiplexed Readouts and Application in Situ Dr. Sunil Kumar, Dominic Alibhai, Dr. Anca Margineanu, Romain Laine, Dr. Gordon Kennedy, Dr. James McGinty, Sean Warren, Douglas Kelly, Dr. Yuriy Alexandrov, Dr. Ian Munro, Dr. Clifford Talbot, Dr. Daniel

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W. Stuckey, Dr. Christopher Kimberly, Dr. Bertrand Viellerobe, Dr. Francois Lacombe, Prof. Eric W.-F. Lam, Dr. Harriet Taylor, Prof. Margaret J. Dallman, Prof. Gordon Stamp, Dr. Edward J. Murray, Dr. Frank Stuhmeier, Dr. Alessandro Sardini, Prof. Matilda Katan, Dr. Daniel S. Elson, Prof. Mark A. A. Neil, Dr. Chris Dunsby, Prof. Paul M. W. French ChemPhysChem 2011; Volume 12, Issue 3, pages 609–626, February 25, 2011

Naoyuki Kondo, Kosuke Miyauchi, Zene Matsuda UNIT 26.9 Monitoring Viral-Mediated Membrane Fusion Using Fluorescent Reporter Methods Current Protocols in Cell Biology 2011; Published Online: 1 MAR 2011

Shiye Chen, Yongxu Zhu, Weimina Xia, Shunren Xia and Xiaoyin Xuc Automated analysis of zebrafish images for phenotypic changes in drug discovery Journal of Neuroscience Methods 2011; 2011 Sep 15;200(2):229-36. Epub 2011 Jul 8.

Stephen T. Buckley PhD, Carlos Medina MD, PhD, Anthony M. Davies PhD and Carsten Ehrhardt PhD Cytoskeletal re-arrangement in TGF-β1-induced alveolar epithelial-mesenchymal transition studied by atomic force microscopy and high-content analysis Nanomedicine: Nanotechnology, Biology and Medicine 2012; 8, 3, 2012, 355-364

S Bhaumik, T V Sekar, J Depuy, J Klimash and R Paulmurugan Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals Gene Therapy 2011, (14 July 2011) | doi:10.1038/gt.2011.101

Alan Hibbitts, Nora Lieggi, Olive McCabe, Warren Thomas, James Barlow, Fiona O’Brien & Sally-Ann Cryan Screening of siRNA nanoparticles for delivery to airway epithelial cells using high-content analysis Therapeutic Delivery 2011; August 2011, Vol. 2, No. 8, Pages 987-999

Miyako Udono, Keishi Kadooka, Shuntaro Yamashita, Yoshinori Katakura Quantitative analysis of cellular senescence phenotypes using an imaging cytometer Methods 2012; Volume 56, Issue 3, March 2012, Pages 383–388

Masahito Hosokawa, Marie Asami, Tomoko Yoshino, Noriyuki Tsujimura, Masayuki Takahashi, Satoshi Nakasono, Tsuyoshi Tanaka, Tadashi Matsunaga Monitoring of benzene-induced hematotoxicity in mice by serial leukocyte counting using a microcavity array Biosensors and Bioelectronics 2012; Available online 27 June 2012 In Press, Corrected Proof

Mayumi Takahashi, Takahiko Shimizu, Takuji Shirasawa Reversal of slow growth and heartbeat through the restoration of mitochondrial function inclk-1-deficient mouse embryos by exogenous administration of coenzyme Q10 Experimental Gerontology 2012; Volume 47, Issue 6, June 2012, Pages 425–431

Bashir M Mohamed, Navin K Verma, Anthony M Davies, Aoife McGowan, Kieran Crosbie Staunton, Adriele Prina-Mello, Dermot Kelleher, Catherine H Botting, Corey P Causey, Paul R Thompson, Ger Jm Pruijn, Elena R Kisin, Alexey V Tkach, Anna A Shvedova, Yuri Volkov Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo Nanomedicine 2012; 05/2012; DOI:10.2217/nnm.11.177

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Masahito Hosokawa, Marie Asami, Seita Nakamura, Tomoko Yoshino, Noriyuki Tsujimura, Masayuki Takahashi, Satoshi Nakasono, Tsuyoshi Tanaka, Tadashi Matsunaga Leukocyte counting from a small amount of whole blood using a size-controlled microcavity array Biotechnology and Bioengineering 2012; Volume 109, Issue 8, pages 2017–2024, August 2012

Friederike I Nollmann, Andrea Dowling, Marcel Kaiser, Klaus Deckmann, Sabine Grösch, Richard ffrench-Constant and Helge B Bode Synthesis of szentiamide, a depsipeptide from entomopathogenic Xenorhabdus szentirmaii with activity against Plasmodium falciparum Beilstein Journal of Organic Chemistry 2012; 8: 528–533.

Constantin Radu, Hosna Sana Adrar, Ab Alamir, Ian Hatherley, Trung Trinh, Hakim Djaballah Designs and Concept Reliance of a Fully Automated High-Content Screening Platform Journal of Laboratory Automation 2012; Online First

Frans Cornelissen, Miroslav Cik, Emmanuel Gustin Phaedra, a Protocol-Driven System for Analysis and Validation of High-Content Imaging and Flow Cytometry Journal of Biomolecular Screening 2012; Online First

N.S. Pitangui, J.C.O. Sardi, J.F. Silva, T. Benaducci, R.A. Moraes da Silva, G. Rodrı´guez-Arellanes, M.L. Taylor, M.J.S. Mendes-Giannini and A.M. Fusco-Almeida Adhesion of Histoplasma capsulatum to pneumocytes and biofilm formation on an abiotic surface Biofouling 2012; Vol. 28, No. 7, August 2012, 711–718

K. Tsutsumi, H. Fujikawa, T. Kajikawa, M. Takedachi, T. Yamamoto, S. Murakami Effects of L-ascorbic acid 2-phosphate magnesium salt on the properties of human gingival fibroblasts Journal of Periodontal Research 2012; Volume 47, Issue 2, pages 263–271, April 2012

Shum, David; Bhinder, Bhavneet; Radu, Constantin; Calder, Paul; N. Ramirez, Christina; Djaballah, Hakim An Image-Based Biosensor Assay Strategy to Screen for Modulators of the microRNA 21 Biogenesis Pathway Combinatorial Chemistry & High Throughput Screening 2012; Volume 15, Number 7, August 2012 ,

pp. 529-541(13) Sebastian Munck, Katarzyna Miskiewicz, Ragna Sannerud, Silvia A. Menchon, Liya Jose, Rainer Heintzmann, Patrik Verstreken and Wim Annaert Sub-diffraction imaging on standard microscopes through Photobleaching Microscopy with non-linear Processing Journal of Cell Science 2012; Online First

Stephen Paul Samuel, Namrata Jain, Frank O’Dowd, Toby Paul, Dmitry Kashanin, Valerie A Gerard, Yurii K Gun’ko, Adriele Prina-Mello, Yuri Volkov1 Multifactorial determinants that govern nanoparticle uptake by human endothelial cells under flow International Journal of Nanomedicine 2012; 7 2943–2956

Peter A. Bain and Kathryn A. Schuller Use of Fluorogenic Probes To Differentiate between Hydrophilic and Lipophilic Antioxidant Activity in a Fish Cell Line Journal of Agricultural and Food Chemistry 2012; 60 (3), pp 699–705

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JOANNE LYSAGHT, NAVIN K. VERMA, ELAINA N. MAGINN, JACQUELINE M. RYAN, GIUSEPPE CAMPIANI, DANIELA M. ZISTERER, D. CLIVE WILLIAMS, PAUL V. BROWNE, MARK P. LAWLER and ANTHONY M. McELLIGOTT The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells INTERNATIONAL JOURNAL OF ONCOLOGY 2012; September 25, 2012

Gabriel A. Quiñones, Travis I. Moore, Katrina Nicholes, Hyunjae Lee, Sudong Kim, Laura Sun, Noo Li Jeon, and Jean-Philippe Stephan Application of a new wall-less plate technology to complex multistep cell-based investigations using suspension cells Blood, Feb 2013; 121: e25 - e33.

R. Jeffrey Neitz, Steven Chen, Frantisek Supek, Vince Yeh, Danielle Kellar, Jiri Gut, Clifford Bryant, Alejandra Gallardo-Godoy, Valentina Molteni, Steven L. Roach, Arnab K. Chatterjee, Stephanie Robertson, Adam R. Renslo, Michelle Arkin, Richard Glynne, James McKerrow, and Jair L. Siqueira-Neto Lead Identification to Clinical Candidate Selection: Drugs for Chagas Disease J Biomol Screen, Jan 2015; 20: 101 - 111.

Hirohito Ishikawa, Fanxia Meng, Naoyuki Kondo, Aikichi Iwamoto, and Zene Matsuda Generation of a dual-functional split-reporter protein for monitoring membrane fusion using self-associating split GFP Protein Eng. Des. Sel., Dec 2012; 25: 813 - 820.

PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation Katherine J. Hands, Delphine Cuchet-Lourenco, Roger D. Everett, and Ronald T. Hay J. Cell Sci., Jan 2014; 127: 365 - 375.

Constantin Radu, Hosna Sana Adrar, Ab Alamir, Ian Hatherley, Trung Trinh, and Hakim Djaballah Designs and Concept Reliance of a Fully Automated High-Content Screening Platform Journal of Laboratory Automation, Oct 2012; 17: 359 - 369.