indicatii metodice medgen

8/9/2019 indicatii metodice medgen

1/22

I. CELLULAR PATHOLOGY.

IRREVERSIBLE CELL DISTURBANCES.

NECROSIS. APOPTOSIS.

Microspecimens

2. Acute tubular necrosis. (H-E)

153. Pancreonecrosis. (H-E) 81. Caseous necrosis of lymp no!e in tuberculosis. (H-E)

". #scemic infarction of te spleen. (H-E)

Macrospecimens

151. $o% (upper) e&tremities 'an'rene.

131. Pancreonecrosis.

3. Caseous pneumonia.

11. Coa'ulatie necrosis of te spleen.

13. *acrofocal postinfarction car!iosclerosis.

Eec!ronom"cro#rap$"

1.Cellular necrosis+ ,ariopy,nosis.


2/22

II. CELLULAR PATHOLOGY.

ACCUMULATIONS% PATHOLOGIC CALCI&ICATION.

Microspecimens

18. enal emosy!erosis. ( H-E)135. /aun!ice of te lier. ( H-E)

10. metastatic calcinosis of te ,i!ney. ( H-E)

Macrospecimens

10. Heart lipomatosis.

5. *elanomas metastasis into te lier.

2. ro%n atropy of te eart. ". iliary calculi.

8. enal calculi.


3/22

III. CELLULAR PATHOLOGY.

IRREVERSIBLE CELL DISTURBANCES.

NECROSIS. APOPTOSIS.

Microspecimens

10. enal amyloi!osis (4on'o-re!)

18. enal emosy!erosis. ( H-E)

135. /aun!ice of te lier. ( H-E)

10. metastatic calcinosis of te ,i!ney. ( H-E)

18. Central artery yalinosis of splenic folicules.

25. $iers fat !e'eneration.

Macrospecimens

82. enal amyloi!osis.

10. Heart lipomatosis.

5. *elanomas metastasis into te lier.

2. ro%n atropy of te eart.

". iliary calculi.

8. enal calculi.

Eec!ronom"cro#rap$"

. *yocar!ial amyloi!osis

3. $ier fatty can'e (epatocytes steatosis)


4/22

General medicine

TOPIC' HEMODYNAMIC DISORDERS

Macrospecimens

0. *yocar!ial infarction.

13. *acrofocal postinfarction car!iosclerosis

38. Pulmonary emorra'ic infarction.

1. utme' lier (cronic epatic con'estion). 11. #scemic infarction of te spleen.

Microspecimens

Pulmonary emorra'ic infarction. ( H-E)

5. enal infarction. ( H-E)

0. Cronic pulmonary con'estion. ( H-E)

1. utme' lier (cronic epatic con'estion). ( H-E)

Eec!ronom"cro#rap$"

5. *yocar!ial infarction+ iscemic sta'e.


5/22

General medicine

IV. HEMODYNAMIC DISORDERS II

Macrospecimen

3. Parietal trombus in te ab!ominal aorta

1. Cronic car!iac aneurysm%it trombosis.

3. 6romboembolism of pulmonary artery.

85. acterial embolism of te 'lomerular capilaries

2. Cancers metastasis in lun's.

121. Cerebral emorra'e.

Microspecimen . 6rombus in te ein. (H-E)

11. purulent embolic nepritis. (H-E)

1. $ympatic essels cancerous embolism. (H-E)

13. 7iape!esis emorra'e in te brain(H-E)

Eec!romicro#rap$"

". ta'es #+ ##+ ### of trombus formation

#. trombocyte a''lutination. 6e first fi'ure so%s te place of ascular

lesion. 6e mitocon!ria are tumefacte! an! omo'eni9e!+ te suben!otelial

layer is e!ematous te colla'en fibers are !issociate!: te unmo!ifie!

trombocytes approace te place of en!otelial lesion.

##. 6e transformation of fibrino'en into fibrin.

6e 9one of en!otelial lesion contains !e'ranulate! trombocytes an!

a''lomeration of fibrin filaments+ %ic a!ere to te %all.

###. Erytrocyte a''lutination. 6e lumen of te essel contains !e'ranulate!

trombocytes+ %ile bet%een tem tere are fibrin filaments an!

a''lutinate! erytrocytes.


6/22

ACUTE AND CHRONIC IN&LAMMATION

Macrospecimen

((.;ibrinous pericar!itis.

().7ifuse car!iosclerosis.

)(.Ecinococus into eart

*).;ocal pneumonia %it abscess formation.

**.$obar pneumonia ('rey epatisation).

*+.;ibrinous pleuritis

(,).;ibrinous peritonitis.

Microspecimen

().#nterstitial myocar!itis.

-).;ibrinous pericar!itis.

).Pyo'enic leptomenin'itis.

*).asal polyp.

Eec!romicro#rap$" /.

Le01oc"!e2s perip$era posi!ion aon# !$e en3o!$eia s0r4ace.

6is process of leu,ocyte accumulation is calle! mar'ination.

ubse


7/22

IMMUNOPATHOLOGIC PROCESSES

*icrospecimen

)55. Hyperplasia of te lienal follicles in anti'enic stimulation

(H.E.stain).

)5(. Hypoplasia of te lienal follicles in te mi&e! immuno!ificient

syn!rome (H.E.stain).

(/*. Acci!ental inolution of te tymus (H.E.stain).

(+. Autoimmune tyroi!itis (H.E.stain).

19. electronomycrography 6#omer0onep$ri!is in SLE7


8/22

ADAPTIVE AND COMPENSATORY PROCESSES

Macrospecimen

+.$eft entricular ypertropy.

,.i't entricular ypertropy.85.@rinary bla!!er %all ypertropy in prostate a!enoma.

)5.ro%n atropy of te eart.

(58. Atropy of te oary.

.Hy!roneprosis.

()*.Hy!rocepaly.

Microspecimen.

*,.ranulation tissue.(H-E)

*-.*yocar!ial ypertropy. .(H-E)

*. lan!ular yperplasia of te en!ometrium. .(H-E)

(,5.*acrofocal postinfarction car!iosclerosis. .(H-E)

Eec!ronomicro#rap$"

(5.e'eneratie ypertropy of te myocar!ium.


9/22

INTRODUCTION TO NEOPLASIA

EPITHELIAL TUMORS

*acrospecimens

1. Carcinoma of laryn&.

50. Carcinoma of esopa'us.

". Carcinoma of stomac.

30. Central cancer of lun's.

. Cancers metastasis into lier.

2. Cancers metastasis into lun's.

*icrospecimens

". Papilloma of s,in.

8. A!enocarcinoma.

12.


10/22

INTRODUCTION TO NEOPLASIA

MESENCHYMAL TUMORS.

TUMORS O& MELANOPOETIC SYSTEM.

Macrospecimen

)*.*y&oma of eart.

/,.*etastasis of melanoma into lier.

(5+.;ibroleiomyoma of uterus.

()).rain tumor ('lioblastoma).

Microspecimen

+).Caernous eman'ioma into lier.(H-E)

+*.;ibrosarcoma.

+(.;ibroleiomyoma of uterus. (picrofucsin+ Ban ieson)

(-*.*etastasis of melanocarcinoma into ,i!ney.


11/22

IN&ECTIOUS DISEASESViral and Bacterial Infections

Microspecimens

((/. @lceratie-necrotic traceitis in 'ripe (H.E.stain).

(5-. Hemorra'ic pneumonia in 'ripe (H.E.stain).

88. ;ibrinous traceitis (in !ipteria) (H.E.stain).

)-. $ympocytic menin'itis (H.E.stain).

Eec!ronomicro#rap$"

)8. teatosis of myocar!ium.


12/22

9. BACTERIAL IN&ECTIONS

*acropreparates

12. Purulent leptomenin'itis

*icropreparates.

00. ;ibrinous traceitis (in !ipteria).

28.Purulent leptomenin'itis.

1. Purulent embolic myocar!itis


13/22

TUBERCULOSIS% AIDS.

Macroprepara!es

++.;ibro-caitary tuberculosis.

+*.Caseous pneumonia.(++.Peribroncial lymp no!es tuberculosis.

(,*.6uberculous spon!ylitis (osteomyelitis).

Microprepara!es.

/8.*iliary lun's tuberculosis (H.E.stain).5.*iliary liers tuberculosis (H.E.stain).).*iliary ,i!neys tuberculosis (H.E.stain).


14/22

9II. SEPSIS

*acropreparates

1. @lceratie - Polypous en!ocar!itis of aortic ale.

85. Purulent embolic nepritis.

*icropreparates.

11. Purulent embolic nepritis.

1. Embolic purulent myocar!itis.

13. Purulent pmbolic encepalitis.

11". Aortic ale in bacterial en!ocar!itis.


15/22

ATHEROSCLEROSIS. HYPERTENSIVE VASCULAR DISEASE.

Macrospecimens

(.Aterosclerosis of te aorta (fibrous pla


16/22

ISCHEMIC HEART DISEASE

Macrospecimens

8.*yocar!ial infarction.)+.Heart rupture in myocar!ial infarction.

(*.*acrofocal postinfarction car!iosclerosis.

(5.Cronic car!iac aneurysm %it mural trombi.

(.Car!iac trombosis.

((.;ibrinous pericar!itis.

Microspecimens

((.6rombosis of te coronary artery (H.E.stain).

-,.*yocar!ial infarction (H.E.stain).

-,a.*yocar!ial infarction ('ranulation tissue) (H.E.stain).

(,5.*acrofocal car!iosclerosis postinfarction (picrofucsin+ an ieson stain).

Eec!ronomicro#rap$"

(5.Ischemic stage of myocardial infarction.Electron microscopic appearanceD can'es in myocar!ial cells inclu!in'

s%ellin' of te mitocon!ria an! en!oplasmic reticulum+ nuclear py,nosis+ an!

early !e'eneration of te sarcolema can be seen %itin 1 our after te onset of

iscemia.


17/22

Disor3ers o4 $ema!opoe!ic s"s!em. Anemia% neopasms.

MACROSPECIMENS

(+). 6e spleen in C*$

(+*.*esentetrial lymp no!e in C$$(+,.one marro% in leucosis.

+.4i!ney in leucosis.

(+-.$ympatic no!e in Ho!',ins !isease.

(+/.pleen in Ho!',ins !isease.

MICROSPECIMENS

,-.$ier in C*$.

,/.$ier in C$$(+,.Plasmocytoma.

,.$ympatic no!e in Ho!',ins !isease.

Eec!ronomicro#rap$"

(+. *yeloma cell.


18/22

Systemic Connective Tissue Diseases (Rheumatic fever)

MACROSPECIMENS

-. eumatic mitral malformation. . $eft atrium roun! trombus.

((.;ibrinous pericar!itis.(). 7iffuse car!iosclerosis.

(-.onbacterial errucous en!ocar!itis

(. 6romboen!ocar!itis.

MICROSPECIMENS

,8. eumatic 'ranulomatous en!ocar!itis (H.E.stain).()/. 6romboen!ocar!itis (H.E.stain).(),. Periarteritis no!osa (H.E.stain). -5. eumatic en!ocar!itis (lue tolui!ine).

Eec!ronomicro#rap$"

(. ;ibrinoi! intumescence of te connectie tissue.

(8. lomerulonepritis in $E.


19/22

Pathology of stomach and esophagus.

MACROSPECIMENS

,8. Esopa'eal carcinoma.

,(. astric polip

,).Cronic 'astric ulcer. ,*.Cronic 'astric ulcer %it perforation.

,+. Cronic !uo!enal ulcer.

-5. astric a!enocarcinoma.

MICROSPECIMENS

(/-. Acute 'astric ulcer. (H.E.stain).

/. Cronic 'astric ulcer in acutisation. (H.E.stain).

(8).on!iferentiate! 'astric carcinoma (tubular a!enocarcinoma).(H.E.stain).

(8)a. metastasis of 'astric carcinoma into lymp no!e. (H.E.stain).


20/22

Intestinal disorders.

MACROSPECIMENS

,,. Acute fle'monous appen!icitis %it periappen!icitis.

-(. Cancer of si'moi! colon.

MICROSPECIMENS

. Acute fle'monous-ulceratie appen!icitis %it periappen!icitis.

(H.E.stain).

a. Cronic appen!icitis %it lumen narro%in'. (H.E.stain).

))). Appen!iceal mucocele. (H.E.stain).

+a. *ucinous a!enocarcinoma of te colon. (H.E.stain).

Intestinal infections.


21/22

MACROSPECIMENS

,.Encepaloi! mo!ifications of Peyr patces in typoi! feer. ,/. ;ibrinous colitis in ci'ellosis (!ysentery).

MICROSPECIMENS

8*. ecrosis of Peyr patces in typoi! feer. (H.E.stain).

8+. *esenteric lymp no!es in typoi! feer. (H.E.stain).

8,. ;ibrinous colitis in ci'ellosis (!ysentery). (H.E.stain).


22/22

DISEASES o4 IN&ANCY an3 CHILDHOOD

Prenatal pathology

/: Con'enital eart !efectsD ventricular septal defect.

(,/: Con'enital malformationD anencephaly.

(,: Con'enital malformationD encephalocele.

()*:Hydrocephalus.

-:Polycystic kidneys.

//:Polycystic liver.

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