infectious diseases unit 2 lesson 4 plan
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Infectious Diseases Unit 2 Lesson 4 plan. Do Now. What is the difference between correlation and causation? How could you prove causation?. Robert Koch – connecting the dots to disease. Bacillus anthracis. Identifying the infectious agent – Koch’s postulates. - PowerPoint PPT PresentationTRANSCRIPT
Infectious DiseasesUnit 2 Lesson 4 plan
Do Now
• What is the difference between correlation and causation?
• How could you prove causation?
Robert Koch – connecting the dots to disease
Bacillus anthracis
Identifying the infectious agent –
Koch’s postulates
1. Association – It must always be present in every case – but not in healthy animals.
2. Isolation – It must be isolated from the sick animal into pure culture.
3. Causation – The pure microbe must cause the disease in a healthy animal.
4. Re-isolation - When the microbe is re-isolated from the sick animal it must be the same as the original.
Applying Koch’s postulates to cholera!
1. Association – It must always be present in every case – but not in healthy animals. 2. Isolation – It must be isolated from the sick animal into into pure culture.
3. Causation – The pure microbe must cause the disease in a healthy animal.
4. Re-isolation - When the microbe is re-isolated from the sick animal it must be the same as the original.
Sack et al., 2004
Applying Koch’s postulates to cholera!
1. Association – It must always be present in every case – but not in healthy animals.
2. Isolation – It must be isolated from the sick animal into into pure culture.3. Causation – The pure microbe must cause the disease in a healthy animal.
4. Re-isolation - When the microbe is re-isolated from the sick animal it must be the same as the original.
Sack et al., 2004
Vibrio cholera
Applying Koch’s postulates to cholera!
1. Association – It must always be present in every case – but not in healthy animals.
2. Isolation – It must be isolated from the sick animal into into pure culture.
3. Causation – The pure microbe must cause the disease in a healthy animal. 4. Re-isolation - When the microbe is re-isolated from the sick animal it must be the same as the original.
Vibrio cholera
Applying Koch’s postulates to cholera!
1. Association – It must always be present in every case – but not in healthy animals.
2. Isolation – It must be isolated from the sick animal into into pure culture.
3. Causation – The pure microbe must cause the disease in a healthy animal.
4. Re-isolation - When the microbe is re-isolated from the sick animal it must be the same
as the original.
Vibrio cholera
Sack et al., 2004
Wrap up:Sometimes Koch’s postulates
can’t be fulfilled!1. Association – It must always be present in every case – but not in healthy animals*.
2. Isolation – It must be isolated from the sick animal into pure culture**.
3. Causation – The pure microbe must cause the disease in a healthy animal.
4. Re-isolation - When the microbe is re-isolated from the sick animal it must be the
same as the original.
*Typhoid Mary.
**Leprosy or the plague.
• Complete the case study
Homework