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Melur K. (Ram) Ramasubramanian, Vice President for Research Michael Straightiff, Executive Director Licensing & Ventures Group Innovation and Entrepreneurship Ecosystem at UVA

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Page 1: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Melur K. (Ram) Ramasubramanian, Vice President for ResearchMichael Straightiff, Executive Director Licensing & Ventures Group

Innovation and Entrepreneurship Ecosystem at UVA

Page 2: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

2

Research, Innovation, and Entrepreneurship

Data Science

• Research –• Discovering how nature and manmade systems work and how these systems are

interrelated.

• Innovation –• Applying creativity to develop novel solutions to a problem. A successfully implemented

solution is recognized as an innovation. • Creativity may be enabled by researching on the topic for a while and be able to connect the

dots leading to an innovation.

• Entrepreneurship –• Recognizing opportunities in a timely fashion, bringing resources to develop promising ideas

fully, and take the differentiated (and IP protected) solution to the market.

Page 3: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Bayh-Dole permits universities that receive federal funding, such as the University of Virginia, businesses, or non-profit organizations to elect to pursue ownership of an invention, rather than obligating inventors to assign inventions to the federal government.

The Bayh-Dole Act of 1980

Visit bayhdole.lvg.virginia.edu for more information

Page 4: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Bayh Dole Responsibilities

• In exchange for the receipt of federal research funds and the University’s election of title to intellectual property generated from federal support, the University must:

• Timely prepare and file patent applications• Seek “expeditious practical application” (commercialization) of such

intellectual property• Demonstrate a preference for small business and domestic

manufacture• Report regularly to the United States government on compliance with

the Act.

Page 5: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Faculty and partners do better basic research after immersing themselves in translational challenges!

Basic Discovery & understanding

The “Full Circle” of Translational Research

Therapeutic or diagnostic target

identification

Synthesis of drug or development of

prototype device or process

Pre-Clinical Testing

Human testing,Clinical Trials

Utilization research,Product launch

Clinical observation, post-introduction

monitoring

Page 6: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Entrepreneurship Education

Innovation & Entrepreneurship at UVA

Research Commercialization

Executive VP & Provost

Economic Development

Executive VP & Chief Operating Officer

Undergraduate

Graduate

Entrepreneurship Advisory Council

Page 7: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Research & Discovery Commercialization at UVA

Page 8: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

“I believe that we should strive to be both great and good in all that

we do…”

Page 9: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

To maximize the intellectual, societal, and economic impact of UVA

discoveries via commercialization.*

UVA LVG Mission Statement

STRATEGIC GOAL III. ENABLE DISCOVERIES THAT ENRICH AND IMPROVE LIVES

*Revision in progress.

Page 10: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

University of Virginia Licensing & Ventures Group

[email protected]

434-924-2175

lvg.virginia.edu / [email protected] / 434-924-2175

Learn morelvg.virginia.edu / [email protected] / 434-924-2175

Our ApproachWe partner with faculty, entrepreneurs, and investors to bring innovations discovered at UVA into the marketplace.

ENGAGEWe work with creators todiscover the innovation’ssmartest path to impact

PROTECTWe navigate the legal & patenting process to protect ideas developed at UVA

DEVELOPWe connect and promote innovations to our partners and industry

ACCELERATEWe provide resources and expertise to support the entrepreneurial and investment process

IMPACTIDEA

ServicesCORE BUSINESS• Prior Art Searching• Patent Preparation/Prosecution• Federal/Sponsor Compliance• Business Development• Licensing/Contracting

OTHER SERVICES• Translational Research Support• Research Development• Experimental Design

(for patentability)• Outreach/Training• Graduate Student Internships• Business Advisory Services

INCUBATOR SPACE• UVA LVG Incubator work space

available for UVA faculty, staff,and students daily use

• Ideal for groups of all sizes in need of meeting, conference, workshop and programming space

• A unique venue for creative thinking and innovation

[email protected]

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Page 12: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors
Page 13: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors
Page 14: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors
Page 15: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Conventional Metrics

Invention Disclosures

Patent Applications Filed/Patents Issued

Transactions

New Ventures Licensed

Page 16: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

$400M

$350M

$450M

$500M

$300M

$250M

$200M

$150M

$100M

$50M

250

200

150

100

50

0

RESE

ARCH

EXPE

ND

ITU

RES

ANNUAL REVENUE

DISCLOSURES

PROVISIONALS FILED

DEALS

FIRST NON-PROVISIONALS FILED

PATENTS ISSUED

NEW VENTURESCREATED

Metrics

5

38

54

80

113

203

7

43

5969

82

105

204

7

33

51

71

87

8

54

47

34

83

176

4

3429

59

90

162

$397,458,000

$469,682,000

$527,185,662

$373,218,000

187$358,576,000

$386,828,000

2016$7,492,073

2017$3,354,570

3

77

98

213

2018$2,481,903

2015$2,417,135

2014$3,595,592

2013$2,095,388

40

52

9

78

125

238

2019

44

Page 17: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Among “Reputational” Peers (16) (2018)

16th in Research Expenditures

5th in Research Expenditures/Invention Disclosure

7th in Research Expenditures/Deal

Among Research Expenditure Peers (13) ($465-$612 MM w/Medical School) (2018)

7th in Research Expenditures

3rd in Research Expenditures/Invention Disclosure

2nd in Research Expenditures/Deal

Metrics - Peer Group Comparisons*

*Association of University Technology Managers - Annual Licensing Survey (2018).^ National Science Foundation HERD Survey (2017).$Assessment of Virginia’s Research Assets. Teconomy Partners, LLC. (2018).

Among Top Ranked Universities by Total Research Expenditures^ (51) (2017)

51st in Research Expenditures

13th in Research Expenditures/Disclosure

11th in Research Expenditures/Deal

Among Commonwealth of Virginia Peer Universities (2013-2017) $

~42% of reported invention disclosures

~48% of issued patents

~57% of deals$

Page 18: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

UVA Innovation Revenue Distribution Formula

35% Innovators

10% Research Support for Innovators

10% Innovator’s Departments

10% Innovator’s School

35% UVA Innovation &Scholarly Activities Fund

Page 19: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

UVA LVG Seed Fund

UVA HS Venture Fund

Company formation, incubation, and staffing

Entrepreneur/Executive/Expert-In-Residence

Expanding LVG’s Offerings

STRATEGIC GOAL IV. Lead economic development through academic discovery and entrepreneurship

Page 20: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Established 2015

$10 MM “evergreen” Seed Fund

5 member, independent oversight committee (alumni VC)

8 initial/2 follow-on investments

$3.253 MM invested

1 exit/7 investments remain

Unrealized portfolio value: $2.975 MM

Subsequent capital raised: $33 MM

UVA LVG Seed Fund Established 2017

Administrative management by LVG

$15 MM Fund

5 member oversight committee

5 initial/4 follow-on investments

$7.45 MM invested

5 investments remain

UVA HS Venture Fund

Page 21: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Establishment of UVA LVG based Entrepreneur-in-Residence program

Partnering with the Community

Page 22: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Curricular

22

Community

Student

Research

Corporate

Schools iLab SchoolsLVG

LVG Health System

Experiential/Training

Translational Commercial

iLabEconomic

Development

SchoolsiLab

Health SystemLVG

LVGIvy, Coulter, Launchpad

Licensing, Seed Fund, Venture Fund, EIR

Venture Fund, EIR, HS CIO

Degrees/Course offerings, Entrepreneurship Minor, PhD+

ECUP, iCorps, iLAB Summer Accelerator,PIKE Fellows, Galant Challenge

Catalyst

iLAB Summer Accelerator

Pre-Seed SeedEarly

VentureVenture

Seed Fund Venture Fund

Due Diligence in Seed Fund Investing, Patent/Transactions

Law Clinic

THRIV

Page 23: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

New Ventures

Licensing

Grant

Pre-Seed

Seed

Venture

Page 24: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Collectively, our research productivity, quality, and impact are strong but could be stronger.

Coordination of resources from across Grounds with common intent of commercialization, economic development, and/or financial return

Strengthening Our Impact

Page 25: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

UVA LVGFall Open HouseWe welcome UVA faculty, researchers, innovators, community partners, andentrepreneurship enthusiasts to:

GET TO KNOW OUR TEAMMEET OUR STARTUP COMPANIES CELEBRATE INNOVATION AT UVA

TUESDAY,SEPTEMBER 17 TH

4 : 30 – 7: 00 PM

722 Preston Avenue Suite 107

Charlottesville, VA

appetizers and drinks will beserved

ride-sharing encouraged overflow parking available after 5:00PM at 800 Preston Ave (region ten building)

Page 26: Innovation and Entrepreneurship Ecosystem at UVA · Innovation and Entrepreneurship Ecosystem at UVA. 2 Research, Innovation, ... We partner with faculty, entrepreneurs, and investors

Discussion