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Page 1: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,
Page 2: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

Blau Farmacêutica is currently one of the leading

pharmaceutical companies in LATAM countries

making highly complex medicines, which are essential

to human health, specialized in oncology, nephrology,

hematology, infectology and among others.

Located in the city of Cotia at São Paulo metropolitan

center, Blau Farmacêutica has three “state of the

art” production sites with fourteen production

areas sorted by therapeutic class, using the most

modern production and quality control equipments.

Its manufacturing sites comply with the good

manufacturing practices and quality control required

by the most demanding sanitary authorities in the

world, including Anvisa, Invima and others.

01

INNOVATION AND TECHNOLOGY FOR LIFE THIS IS THE MISSION OF A COMPANY THAT PuRSuES ExCELLENCY.

Page 3: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

02

The R&D department of Blau Farmacêutica is divided in two expertise

sectors: biological products and synthetic drugs. They develop new

products, formulations, processes and analytical methodologies. They

use the latest generation of equipments, which are only found at

universities and advanced research laboratories. It has a professional

team that includes Post-Doc, Doctors, Masters and others.

The analytical methodologies used for quality control follow both

Brazilian and international monographies in their latest releases

and utilizes the company’s own developed validated methods.

Its equipments are qualified and its processes validated using

modern tools to ensure the quality of the process with safety and

traceability information.

Page 4: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

03

Its quality policy called “BLAU TOTAL QUALITY” aims to always

seek, encourage, renew and modify, requiring the highest

quality and technology in every process, product, environment

and life, prioritizing ethics and continuous improvement.

This year, Blau Farmacêutica celebrates 29 years of success

and growth, including in its career the development of

more than 100 different pharmaceutical products meeting

various therapeutic specialties.

Page 5: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

Chile

Brasil

Azerbaijão

Iêmen

Colombia

Paquistão

Costa Rica

Malásia

Equador

Rep. Dominicana

Paraguai

UruguaiArgentina

Tailândia

Panamá

Vietnã

Perú

Blau has maintained an incredible growth of the

2-digit order in the last 5 years. Its plan is so bold,

daring and well-controlled, which is possible to

achieve such results in the face of many economic,

social and market scenarios.

04

The company currently has three subsidiaries in LATAM

countries, including Brazil, Uruguay and Colombia and it is

opening another three: Argentina, Chile and Peru. Their growth

strategy combined with the full acceptance of its products by

the new markets is resulting in the growing demand of their

product line not only in the LATAM countries, but also in many

other countries around the world, where the company already

exports its products to, due to their technical competence

which ensures the quality, efficacy and safety for its medicines.

38% 33%60% 11%

33% 27%*

2011 2012 2013 2014 2015 2016

R$ 131.323.506 174.145.343 277.697.714 307.437.905 408.604.181 520.000.000

(*Expected 2016)

BLAU FAMACÊUTICA – GROWTH DEMONSTRATION

Page 6: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

05

BIOPHARMACEUTICALS Epoetin alpha – rHu (epo)Interferon alpha 2a – alpha 2a (ifn) Interferon alpha 2b – alpha 2b (ifn)Filgrastim – rHu – (g-csf)Molgramostim – (gm-csf)Interferon beta 1a – (ifn)Interleucin – rHu – (il2)Somatropin – rHu – (GH-growth hormone)

BIOSIMILARSEpoetin alfa – rHu (epo) – Eritromax

Filgrastim – rHu – (g-csf) – Filgrastine

ONCOLOGICAL – INJECTABLE Carboplatin – B- PlatinCisplatin – C- PlatinOxaliplatin – GenericCytarabine – CitaraxEtoposide – EpósidoGemcitabine – GenericDacarbazine – GenericDocetaxel – GenericEpirubicin – GenericIdarubicin – GenericFludarabine – GenericIfosfamide – GenericIrinotecan – GenericPemetrexed – GenericVinblastine – GenericVincristine – GenericVinorelbine – GenericMTX – methotrexate – GenericMesna – GenericZoledronic acid – Generic

Ondansetron – Ontrax

ONCOLOGICAL – OralTamoxifen – TaxofenMethotrexate disodium (Oral) – MethotrexateFlutamide – Generic

Bicalutamide – GenericAnastrozole – GenericLetrozole – GenericExemestane – Generic

BLOOD PRODUCTSHuman Immunoglobulin Sol IV – ImmunoglobulinHuman Albumin 20% – Blaubimax

ANTIVIRAL AND ANTIRETROVIRALSAcyclovir – GenericFamciclovir – FanclomaxGanciclovir – GanviraxRibavirin – RibavirinLamivudine – Vudirax

UTERINE STIMULATOROxytocin – Generic

ANAESTHETICSPropofol – PropofolLidocaine HCl – GenericSuccinylcholine – SuccitratEtomidate – GenericRemifentanil – Suremifen

ANTITHROMBOTICSSwine Sodium Heparin – HepamaxSodium Enoxaparin – Enoxalow

THROMBOLYTICSStreptokinase – Streptokinase

ANTIRHEUMATIC Methotrexate disodium (Oral) – Methotrexate

FEMALE HEALTH CARE Tinidazole + Miconazole Nitrate – AnfugineTetracycline + Amphotericin – NovasutinMiconazole Nitrate – GenericTioconazole – Generic

ANTIBIOTICSPenicillanicsBenzyl Penicillin g potassium – AricilinaAmpicillin Sodium – CilinonAmoxicillin + Clavulanate Potassium – DoclaxinOxacillin Sodium – OxanonBenzyl Penicillin procaine + potassium – PenkaronPiperacillin + tazobactam – Pipertazo

NON BETA LACTAMSAmikacin Sulfate – AmicilonVancomycin Hydrochloride – GenericTeicoplanin – TeicostonLincomycin Hydrochloride – LinatronCiprofloxacin – CifloxtronMeropenen – GenericClindamycin – ClindarixClarithromycin – Sumiclar

CEPHALOSPORINCephalothin Sodium – Generic

Cefoxitin Sodium – Cefton

Ceftazidime Pentaidratada – Ceftazidon

Cefazolin Sodium – Fazolon

Cefotaxime – Clafordil

Ceftriaxone disodium Hemieptaidratada – Generic

Ceftriaxone disodium Hemieptaidratada – Triaxton

CHLORAMPHENICOLSodium Succinate of Chloramphenicol – Arifenicol

ACID PUMPER INHIBITOR Omeprazole – Oprazon

Pantoprazole – Generic

OTHER HOSPITAL PRODUCTSSaccharate Ferric Hydroxide – Ferropurum

Atropine Sulfate – Atropion

N-acetylcysteine – Generic

Hydrocortisone – Generic

Diclofenac Sodium – Generic

Dopamine Hydrochloride – Dopabane

Furosemide – Furosetron

Calcium Gluconate

Adrenalin – Efrinalin

Dobutamine – Dobutariston

Magnesium sulfate – Magnoston

Dexamethasone – Metaxon

Aminophylline – Minoton

Verapamil Hydrochloride – Vasoton

Phytomenadione (synthetic vitamin K) – Vikatron

Tranexamic Acid – Generic

Tiocolchicosideo – Generic

Methylprednisolone – Sumitric

PiPE LINEImatinib

Erlotinib

Bortezomib

Sorafenib

Bendamustine Hydrochloride

Capecitabine

Temozolomide

Fluvestranto

Polymyxin B

Liraglutide

Hydroxyurea

Salbutamol

BLAU FARMACÊUTICA’S PRODUCT LINE

Page 7: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

Blau Farmacêutica has a clinical and nonclinical research

department, to conduct post-marketing surveillance (PMS/

Phase IV) studies, prospective studies (Phase I, II and III) and

bioequivalences to prove the quality, effectiveness and safety

of its drug products, always following good clinical practices

and the applicable regulations. This department utilizes tools

that assure the confidentiality and security of the information.

Blau Farmacêutica’s quality assurance goes beyond its own

limits, auditing and qualifying suppliers and customers in order

to ensure the quality and the traceability of its medicines in the

entire productive chain, to the extent of the medicine being

administered to the patients.

Blau has a department of information and technology (IT) that

uses the most modern tools to be connected with its customers

and employees, obtaining quick answers and control of the

information;Blau also has a department for customer services with

a trained team to attend patients and healthcare professionals.

Its Pharmacovigilance system is always monitoring the adverse

reactions in order to find any unknown risks and propose, if

necessary, measures for managing and minimizing risks.

06

Page 8: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

07

Blau farmacêutica besides engaging to develop and produce medicines, is

strongly engaged to social commitment to help many charitable institutions

to carry out social work.

Besides that, the company sponsors many different cultural and sports

projects, working both with and without government support. Thus, it

promotes the exercise of citizenship, working for a fairer society.

Blau believes that one way of improving social health is

through sports activities. Therefore it supports all kind of

sports, highlighting the car racing.

Page 9: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

08

The commitment that Blau has with continued growth is no excuse for the

company to forget what really matters: the environment and the population

across the entire planet. Therefore, Blau has also been investing heavily in

sustainability through internal activities aimed at environmental preservation.

Page 10: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

Blau Farmacêutica knows how to value its stakeholders. Without them,

it would not be possible to write a story of success. These highly skilled

professionals, together with the technology present in the company,

have been enabling Blau to be part of something much greater than the

company itself. For this reason, we have learnt throughout the years to

value respect and solidarity on a daily basis.

This attitude has led to and increase in performance inside the company

and increased the quality of its products and services.

This is Blau, an innovative company that strives to improve and go

beyond excellency in order to ensure that the largest number of people

have access to the most valuable asset that exists: a healthy life.

Page 11: INNOVATION AND TECHNOLOGY FOR LIFE...pharmaceutical companies in LATAM countries making highly complex medicines, which are essential to human health, specialized in oncology, nephrology,

Blau Farmacêutica S/A – Matriz /Headquarter (Brazil)Rodovia Raposo Tavares, Km 30,5number 2.833 • CEP: 06705-030Cotia • São Paulo • BrazilPhone: 55.11.4615.9400Fax.: [email protected]

Plant IIAvenida Ivo Mario Isaac Pires, 7.602CEP: 06720-480 • Pedras • Caucaia • SP • BrasilPhone: (11) 4611-0907Fax: (11) 4611- 0037

Plant IIIRua Adherbal Stresser 84Jardim Arpoador • SP • BrasilPhone: ( 11) 3732-2500Fax: (11) 3732 - 2500 • Ext. line: 2508

Blau Farmacêutica ColombiaTransversal 93, number 53-48 • Int. 51-52Parque Industrial El Dorado • Bogota • ColombiaPhone: (571) 2515622Fax: (571) 2515622 • Ext.: [email protected]

Blau Farma UruguayCalle Dr. Luis Bonavita, number 1.266Floor 1. Of. 105 • Tower IV. WTC (11.300)Montevideo • UruguayPhone: (598) 2626 1616Fax: (598) 2626 [email protected]

www.blau.com.br