IntroducingIntroducing

Anodyne® TherapyAnodyne® Therapy

Anodyne® Therapy Systems

www.rapidhealing.com.au Introducing Anodyne 2

Professional SystemModel 480

8 Pads

Home SystemModel 120

4 Pads

Mobile System

OTG Back 1 Wrap Pad

Monochromatic• Single wavelength of light (890nm)• Absorbed by hemoglobin

Infrared• Invisible to the human eye• Penetrates the body by approximately 5 cm

Energy• 780 mw power per therapy pad• Photo energy – not thermal

Flexible Therapy Pads• Maximizes efficacy and ease of use

What is Anodyne® Technology?Monochromatic InfraRed Energy (MIRE™)

www.rapidhealing.com.au Introducing Anodyne 3

IR is absorbed by hemoglobin and endothelial cells.

Resultant photo-dissociation of NO from hemoglobin

Hypothesis of MIRE™

www.rapidhealing.com.au Introducing Anodyne 4

Anodyne Pulsed Photon Energy Penetrates the Body

www.rapidhealing.com.au Introducing Anodyne 5

Level of energy emitted with Anodyne vs. a Respond Laser (veterinary medicine for

wound healing). Light does not have to be lased to penetrate the skin.

Penetration of light through the hand.Notice how the veins absorb the light

Anodyne Delivers Pulsed Photon Energy – not thermal energy – 780 mw per therapy pad

Baseline image Placebo40%

Increase

MIRE™ 400%

Increase

Improved Microcirculation

www.rapidhealing.com.au Introducing Anodyne 6

Improved Microcirculation as shown by Moore Scanning Laser Doppler Image after 20 minute treatment with Anodyne® Therapy compared with placebo (warmth)

Improved Microcirculation

www.rapidhealing.com.au Introducing Anodyne 7

Heel – 32x perfusion increase

Sacral – 13x perfusion increase Knee – 20x perfusion increase

Improved Microcirculation as shown by Moore Scanning Laser Doppler Image after 20 minute treatment with Anodyne® Therapy

Nitric Oxide Has Many Positive Effects

• Vascular

• Neural

• Wound healing

• Anti-inflammatory

• Anti-bacterial

• Anti-viral

• Bone formation

• Pain relief

www.rapidhealing.com.au Introducing Anodyne 8

Vascular Effects of Nitric Oxide• Dilates existing blood vessels

(arterioles, venules, and lymphatics)

− Increases capillary (nutritional) flow

− Increases antibiotic efficacy

• Angiogenesis…grows new blood vessels

• Decreases edema/swelling/inflammation

− Increased venous evacuation

− Increased lymphatic motility

• Reduces platelet aggregation

Indications for Use

• If therapeutic objectives are to:– Increase circulation– Reduce inflammation– Decrease edema (swelling)– Enhance soft tissue remodeling– Increase osteoblastic proliferation– Reduce pain– Increase sensation

• Far more effective than hot/cold packs, ultrasound, nerve stimulation

www.rapidhealing.com.au Introducing Anodyne 9

• Inflammation/Infection– Bursitis– Osteoarthritis– Tendonitis– Plantar Fasciitis– Lateral Epicondylitis– Neuritis– Synovitis– Bell’s Palsy– Cellulitis– Osteomyelitis (IV Antibiotics)*

• Range of Motion Deficits– Frozen Shoulder– Contractures

• Orthopedic– Non-Union/Jones Fractures– Degenerative Disc

• Chronic Wounds – Venous, Pressure Ulcers (Arterial)

www.rapidhealing.com.au Case Studies 10

• Pain– Neuralgia– Fibromyalgia– Neuropathic Pain– Ischemic Pain– Chronic Pelvic Pain

• Nerve Entrapments– TMJ– Carpal Tunnel Syndrome– Tarsal Tunnel

• Swelling– Edema– Lymphedema– Sprains and Strains

• Post-Operative – Reduce Swelling and Pain– Speed Healing– Reduce Adhesions/Scarring* Depends on involvement

Summary of Responsive Conditions

Why is Anodyne® Therapy Good For Diabetics?

Diabetes is a vascular disease• Retinopathy• Nephropathy• Peripheral Neuropathy• Autonomic Neuropathy (Gastroparesis; Silent Heart Attacks)• Coronary Artery Disease

Diabetic Patients Don’t Have Enough NO • Reduced production of NO • What little NO is produced is bound tightly to hemoglobin (HgA1c) • Glucose destroys NO

Therefore• More vascular disease• More pain (neuropathic; ischemic)• More non-healing wounds

www.rapidhealing.com.au Introducing Anodyne 11

All symptoms that Anodyne® Therapy is scientifically proven to provide relief for!

• Increased tensile strength of healed tissue– Wounds don’t break down– DPN ulcers don't reappear

• Reduced post-op complications– Keloid scarring– Dehiscence – Infection rates

• Reduced post-operative pain – Decreased edema– Patients ambulating/back in shoes faster

• Faster return of range of motion

www.rapidhealing.com.au Introducing Anodyne 12

Observations over 10+ Years of Use in USA