Think of the MiracleIt was not very long ago that a human baby was born in a non-sterile environment. In fact, this is still true in most of theworld. That tender newborn is thrust from a warm, protectedenvironment, into a world of germs and microbes anxious toattack the unprotected. With no immune system, the infant iseasy prey. As usual, Mother Nature has a plan. The first instinctof all newborns, human or animal, is to breathe. The second isto nurse. It is built into us, and for good reason. The momentyour son or daughter, your kitten or pup, calf or doe, begins tonurse, nature unleashes a cocktail of nutrients that transfer themothers’ immunities and other essential nutrients to thenewborn.

Mothers’ first milk: what anincredible moment this is

Colostrum, better known as Mothers’ Milk, is created by allmammals at birth. This fluid gives the newborn an instant set ofimmunities, plus growth factors that aid the newborn’s body torejuvenate during the stressful process of growth. “Growthfactors supply the necessary building blocks for the newborn,enhancing the growth of cells, muscle, tissue, bone andcartilage.”

What does this have to dowith non-infants and adults?

“As we age, our bodies produce less and less of these vitalfactors, increasing signs of aging, and making it more difficultfor us to fight disease.”

Why you should hug a cow!

Colostrum from cows is loaded with immune, growth and repairfactors and provides humans most of the same benefits that itprovides the newborn calf. Think about it. You likely spend yourtime in a mostly sterile environment, washing your hands,bathing regularly. Does this sound like the life of a cow? They are out there with the dirt and germs. As they encounterthese ‘pathogens’, the bad guys, they develop ‘antigens’, thegood guys. They pass the ‘antigens’, immune factors in theirColostrum. When you consume the Colostrum, your immunesystem has an opportunity to “get familiar” with the antigensand enhance your immune response.

What are the growth factors?

Growth factors including FGF and IGF-1 are substancesnecessary for cell-to-cell interaction. Bovine Colostrum is theonly natural source for IGF-1. FGF is a cell-regenerating factor.FGF targets the replacement of older damaged cells with younghealthy cells. FGF promotes and supports the rejuvenation of allorgans and tissues: immune system, circulatory system, neuro-muscular system, retina, skeletal system, gastrointestinal tract,urinary tract, skin, hair and nails.

All the information provided in this document is intended for your general knowledge only, and is not a substitute for medical advice or treatment for specific medical conditions. You should seek prompt medical care for any specific health problems. Please consult your physician before beginning this or any nutritional or fitness regimen. Thesestatements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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nature’s first and

most perfectfood!

introducingUltra-Pure Colostrum™

Nourish your immune systemwith nature’s perfect food

The IGF-1 is comprised of a family of peptides that play animportant role in growth, development and metabolism. IGF-1has a direct effect on fat cells. It stimulates them to break downtriglycerides and suppresses their ability to store dietary fats.IGF-1 also appears to be the key player in muscle growth. IGF-1 is one of a battery of hormones that serves to maintainblood glucose within a normal range. IGF-1 may affect thelevels of serotonin and dopamine and may thereby brighten the mood.

Autoimmune DiseaseWhen the immune system attacks healthy tissue, it can causevery serious, and often debilitating damage. Research hasshown that colostrum, with its amazing immune factors, may beable to provide relief. Researchers at the University of Alabamaand the Univeristy of Warsaw in Poland discovered a smallprotein chain in colostrum, Proline Rich Polypeptide (PRP),which may help regulate the immune system.

Immune Factors• Immunoglobulins - IgG, IgA, IgM, - substances that

neutralize toxins, viruses, and bacteria, particularly inthe digestive and respiratory systems.

• Transfer factors - allow the body to react quickly tobacteria, viruses and other pathogens for whichimmunity has already been established.

• Cytokines – small proteins that affect the behavior ofother cells. Cytokines act as an anti-inflammatory andhelp boost the production of other antibodies. As wegrow older, however, cytokine production is reduced.Cytokines may also be responsible for regulating theimmune and metabolic responses.

• Lactoferrin– a substance that neutralizes bacteria andhelps release cytokines.

• Proline Rich Polypeptides (PRP) – help regulate theimmune system, especially when the immune system ishyperactive.

Essential GlyconutrientsGlyconutrients are polysaccharides that the body must have forproper cell to cell communication. Resent scientific researchhas demonstrated that essential glyconutrients can have asignificant effect on the health of every organ and system.(Lefkowitz, S), (Gardiner, T)

"... one of the 10 technologies that will change the world."MIT's Technology Review ~ February 2003"…could have an impact on health problems ranging fromrheumatoid arthritis to the spread of cancer cells." MIT'sTechnology Review ~ February 2003

DIRECTIONS:As a dietary supplement, take 1 capsule one to three times daily withmeals, or as directed by your healthcare practitioner.

NOTE: Do not use with aluminum-containing drugs, or any other medication, withoutyour doctor’s approval. High doses of magnesium can have a laxative effect.Reduce dosage if this occurs.

Our Cows are Clean

Collected Solely from USA DairiesCertified FREE of:

• Artificial Hormones• Antibiotics• Pesticides• GMO• BSE

The Ultra-Pure Colostrum™ sold by Rejuvenetics® is of thehighest quality available and is from 1st milking post parturientcows, thereby containing the greatest abundance of immunefactors (specific and nonspecific) available. First milkingcolostrum is in perfect balance, and when ingested in smallamounts it can help normalize, regulate and maintain bodyfunctions – if not by direct action, then by the combined actionof regulating and supporting other organs, glands and systems.

02

Supplement FactsServing Size 1 Capsule Servings Per Container 120

Amount Per Serving % Daily ValueColostrum 500 mg *

*Daily Value not established.

Other Ingredients: Gelatin

Rejuvenetics™ Ultra-Pure Colostrum™

REFERENCES:03

Cytokines effect in rheumatoid arthritis. Maruyama H, Nakajima J, Yamamoto I. Kitasato Arch Exp Med.1987 Sep;60(3):105-21. No abstract available. PMID: 2455094 Bovine colostrum and its antibacterial effect. Infection and Immunity. 57:1227-1234. PubMed ReferenceProline-rich polypeptide from bovine colostrum benefitthe immune system. Immunology. 36:879-881. PubMed ReferenceProline-rich polypeptide (PRP)- from bovine colostrumhas an immunomodulatory effect.Archivum Immunologiae et Therapiae Experimentalis. 41:275-279.Proline-rich polypeptide from colostrum hasimmunoregulatory properties. Molecular Immunology. 12:1277-1282. PubMed ReferenceBovine colostrum used for wound healing in vivo. Science. 219(4590): 1329-31. PubMed ReferenceBovine colostrum containing antibodies to humanrotavirus. Lancet. 2(8665):709-12. PubMed ReferencePrevention of rotavirus infection with bovine colostrumcontaining antibody against human rotavirus. Lancet. 2(8357):1029-30. PubMed ReferenceBovine colostrum to treat rotavirus gastroenteritis ininfants. Journal of Infectious Diseases. 156:158-166. PubMed ReferenceImmunoglobulin components and anti-viral activities inbovine colostrum. 64:274-279. PubMed ReferenceIgA from colostrum used to treat E coli. Scandavian Journal of Immunology. 46:59-66. PubMed Reference

INTESTINALBovine colostrum benefits the human stomach and smallintestine. Gut. 44(2):212-7. PubMed ReferenceBovine colostrum provides passive immunity againstdiarrhoea. Acta Paediatr. 85:125-128. PubMed ReferenceTreatment of Helicobacter pylori infection with oralimmunoglobulins from bovine colostrum. Ailment Pharmacol Therapies. 12:563-568. PubMed ReferenceHelicobacter pylori (H. pylori). The Journal of Infectious Diseases. 177: 955-961. PubMedReferenceColostrum benefits the Leaky gut of alcoholism. The Lancet. 1(8370):179-82. PubMed Reference

Research on Bovine ColostrumGENERAL BENEFITSBovine colostrum offers broad-spectrum benefits forwide-ranging ailments. Medical Journalist Report of Innovative Biologics: TownsendLetters for Doctors and Patients. Walker M. (1999) 74-80. Active chromium complex from bovine colostrum help toregulate blood glucose levels. American Institute of Nutrition. 118(1):39-45. PubMed ReferenceAntioxidant properties of colostrum. Pediatric Research. 24(1):14-9. PubMed ReferenceTreatment of severe eye dryness and problematic eyelesions with bovine colostrum. Adv Exp Med Biol. 350:595-9. PubMed ReferenceProline-Rich Polypeptide (PRP) Complex Isolated fromColostrum for Treatment of Alzheimer's Disease. A Double - Blind Placebo-Controlled Study. ArchivumImmunologiae et Therapiae Experimentalis. 47(6):377-85. PubMedReferenceBovine colostrum has anti-inflammatory benefits andprevents NSAID induced gut damage.Gut. 44:653-658. PubMed Reference

GROWTH FACTORSEffect of growth factors on wound healing. Journal of Surgery Res. 59:236-244. PubMed ReferenceInsuin-like growth factor-1 blood levels are notassociated with prostate specific antigen (PSA) levels orprostate cancer: (Cass TL) A study of 749 patients. Medical College of Wisconsin, Milwaukee,WI www.worldhealth.net/news/prost-igf1/:1999. Insulin and IGF-1 enhance human skeletal musclesynthesis. Journal of Clinical Investigations 96:1722-1729. PubMed Reference

IMMUNE FACTORSTransfer FactorsStructural nature and functions of transfer factors. Annals New York Academy of Sciences. 685:362-8. PubMedReferenceCytokinesCytokines useful in immunodeficient individuals. Journal of Biological Regulators and Homeostatic Agents. 3:121-124. PubMed Reference

Rejuvenetics™ Ultra-Pure Colostrum™

Bovine colostrum has anti-inflammatory benefits andprevents NSAID induced gut damage. Gut. 44:653-658. PubMed ReferenceBactericidal effect of bovine colostrum againstHelicobactor pylori. Journal of Applied Bacteriology 78:655-662. PubMed ReferenceTreatment diarrhea in AIDS patients with bovinecolostrum patients. AIDS. 4:581-584. PubMed ReferenceBovine colostrum and its effect in the human digestive tract.ZH Mikrobiology Epidemiology Immunobiology. 9:101-106.PubMed ReferenceBovine colostrum ameliorates diarrhea caused by E coli. Journal of Pediatric Gastroenterology and Nutrition. 29:452-456.PubMed ReferenceGlyconutrient a novel immune-enhancing polysaccharide.Alternative Medicine Review. 4(2):96-103. PubMed ReferenceColostrums affect against herpes simplex virus. Journal of Clinical Laboratory Immunology. 1:221-224. PubMedReferenceLow colostral IgA associated with cow's milk allergy. Acta Pediatr Scan. 80:1207-1213. PubMed ReferenceProtective potential of colostrum against prospectiveinfluenza viruses. Journal of Tropical Pediatrics. 36(2):94-5. PubMed ReferenceSiber G. (1992) Immune globulin to prevent nosocomialinfection. (Accuaired during hospitalization)New England Journal of Medicine. 327(4):269-71. PubMedReferenceLactoferrinLactoferrin is a lipid A-binding protein. Infection and Immunity. 62:2628-2632. PubMed ReferenceLactoferrin and it’s functions. Lactoferrin: Structure and Function. 1-12. PubMed ReferenceLactoferrin shows potent activity against both humanimmunodeficiency virus and human cytomegalovirusreplication in vitro. Journal of Infectious Diseases. 172:380-388. PubMed ReferenceLactoferrin is studied against human herpes virus. Jpn. Journal of Sci. Biol. 47:73-85. PubMed ReferenceLactoferrin markedly inhibits hepatitis C virus. Biochemical and Biophysical Research Communications. 245:549-553. PubMed ReferenceLactoferrin: A general review. Haematologica 3:252-267. PubMed Reference

Effects of bovine Lactoferrin on colon carcinoma 26 lungmetastasis in mice. Clinical and Experimental Metastasis. 17:35-40. Masaaki I. and etal. (1999)Lactoferrin in the human colon carcinoma. Biochemistry Journal. 308:391-397. PubMed ReferenceAnti ViralTreatment diarrhea in AIDS patients with bovinecolostrum patients. AIDS. 4:581-584. PubMed ReferenceProtective potential of colostrum against prospectiveinfluenza viruses. Journal of Tropical Pediatrics. 36(2):94-5. PubMed ReferenceSiber G. (1992) Immune globulin to prevent nosocomialinfection. (Accuaired during hospitalization)New England Journal of Medicine. 327(4):269-71. PubMed ReferenceColostrums affect against herpes simplex virus. Journal of Clinical Laboratory Immunology. 1:221-224. PubMedReferenceBovine colostrum containing antibodies to humanrotavirus. Lancet. 2(8665):709-12. PubMed ReferencePrevention of rotavirus infection with bovine colostrumcontaining antibody against human rotavirus. Lancet. 2(8357):1029-30. PubMed ReferenceBovine colostrum to treat rotavirus gastroenteritis ininfants.Journal of Infectious Diseases. 156:158-166. PubMed ReferenceImmunoglobulin components and anti-viral activities inbovine colostrum. 64:274-279. PubMed ReferenceAllergiesLow colostral IgA associated with cow's milk allergy. Acta Pediatr Scan. 80:1207-1213. PubMed ReferenceAthleticsBody Composition. Nutrition 17:243-247, 2001. PubMed ReferenceEndurance running in marathoners. Medicine and Science in Sports and Exercise. 22: 207-212.PubMed ReferenceIGF-1, IgG levels during training. Journal of Applied Physiology. 83: 1144-1151. PubMed ReferenceMarathon racing and the effects of fluid replacement,immune function, and psychological factors. Sports Medicine. 15: 116-132. PubMed Reference

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Rejuvenetics™ Ultra-Pure Colostrum™