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Introduction to the Research Process: Introduction to the Research Process: Formulating a Research QuestionFormulating a Research Question
© Fraser Health Authority, 2011
The Fraser Health Authority (“FH”) authorizes the use, reproduction and/or modification of this publication for purposes other than commercial redistribution. In consideration for this authorization, the user agrees that any unmodified reproduction of this publication shall retain all copyright and proprietary notices. If the user modifies the content of this publication, all FH copyright notices shall be removed, however FH shall be acknowledged as the author of the source publication.
Reproduction or storage of this publication in any form by any means for the purpose of commercial redistribution is strictly prohibited.
This publication is intended to provide general information only, and should not be relied on as providing specific healthcare, legal or other professional advice. The Fraser Health Authority, and every person involved in the creation of this publication, disclaims any warranty, express or implied, as to its accuracy, completeness or currency, and disclaims all liability in respect of any actions, including the results of any actions, taken or not taken in reliance on the information contained herein.
Department of Evaluation and Research Services
Library | Education | Administration | Development
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OutlineDERS overviewDefinition of ResearchOverview of Research Process – 9 stepsSources of Research QuestionsForming, refining and assessing research questionTools
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ObjectivesUnderstand the nine major components of the research processUnderstand how to formulate your idea into a researchable questionUnderstand how to asses the feasibility and relevance of research question
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Julie Hadden (604-587-4436), Research Ethics Coordinator
Susan Chunick (604-587-4681), Director
Mary de Vera (604-587-4438), Epidemiologist
Magdalena Swanson (604-587-4637), Research and Grant Development Facilitator
Camille Viray (604-587-4413), Education & Communication Coordinator
Michelle Purdon (604-851-4700 ext. 646832), Manager, Library Services
Department of Evaluation and Research Services
Library | Education | Administration | Development
Lisa Kristiansen (604-587-4445), Evaluation Specialist
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Fraser Health Library Services13 libraries, 1 library manager, 5 librarians and 4 library technicians
Timely access to evidence based information to support patient care
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RCH Library
Staffed Monday-Friday
1 librarian and 1 library technician
SMH Library
Staffed Monday-Friday
1 librarian (5 days) and 1 library technician (2 days)QP Library
Staffed Tuesdays
1 library technician
Fraser Health Library Services
BH Library
Staffed Monday-Thursday
1 librarian
DH Library
Unstaffed
ARHCC Library
Staffed Monday-Friday
1 librarian and 2 library technicians
CGH Library
Staffed Monday-Friday
1 librarian (4 days) and 1 library technician (1 day)
ERH Library
Staffed Tuesdays
1 librarian
FCH Library
Unstaffed
PAH Library
Staffed alternating Wednesdays
1 library technician
RMH Library
Staffed Wednesdays and Thursdays
1 library technician MMH Library
Staffed Thursdays
1 librarianLMH Library
Staffed Fridays
1 library technician
SMH Library
Staffed Monday-Friday
1 librarian and 1 library technician (2 days)
RCH Library
Staffed Monday-Friday
1 librarian and 1 library technician
QP Library
Staffed Tuesdays
1 library technician
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http://research.fraserhealth.ca
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FH Research Study Database
http://researchdb.fraserhealth.ca/ersweb/
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FH Health Research Intelligence Unit How can we help?
Research & Grant Development FacilitatorConducting a search for funding opportunitiesTargeted notification of new funding sources and deadlinesIdentifying a research teamPreparing letters of intentIdentifying resources required for conducting researchFormulating the research budgetFacilitating proposal development in collaboration with researchersUnderstanding FH and funding agency requirements regarding preparation of specific documentsAdministration of funding awards
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FH Health Research Intelligence Unit How can we help?
EpidemiologistSpecifying the research goal, objectives and hypothesisIdentifying measurable outcomesSpecifying the variables for analysisIdentifying sources of dataDeveloping data collection tools for quantitative or qualitative studiesDeveloping the statistical analysis planUnderstanding how to use statistical software, such as SPSS
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Research, Evaluation and Quality Improvement
Research: Undertaken to discover new knowledge, test theories, establish truth, and generalize across time and space
Evaluation: Undertaken to inform decisions, clarify opinions, identify improvements, and provide information about programs and policies within contextual boundaries of time, place, values, and politics
Quality Improvement: a structured approach that focuses on sequential building of knowledge, learn by doing, testing and implementation of change ideas
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Research Process1. Generate idea2. Conduct literature review3. Refine research question4. Plan research methodology5. Create research proposal6. Apply for funding7. Apply for ethics approval8. Collect and analyze data9. Draw conclusions and relate findings
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Step 1: Generate research idea
Identify general area of interestFormulate a preliminary research question that you want to exploreOnce your initial research idea has been formed, it is necessary to think about research intent and previous research
What do you hope to accomplish?Has this research been done before?
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Step 2: Conduct literature review
Review books, journal articles, and other peer reviewed sources such as registries of evidence based research literatureReview the references section of relevant articles to aid in the search for related articlesConducting literature reviews take time, but this is a very important step in the research processThe Fraser Health library can help you with your search
http://fhaweb/Education+and+Research/Library/default.htm
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Step 3: Refine research question
Now that you have exhausted the literature, how has your original research idea changed? Start thinking in more detail
State the problem or research questionWho will your sample include? • Who, where, when, and what
What items will be measured? How will they be measured?
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Step 4: Plan research methodology
Select research methods which will allow you to answer your research question
Consider:Who are the subjects and how will they be recruitedWhat measures do you intend to useWhat will be the procedure for recruiting subjects or accessing dataWhat will be the procedure for interventionsJustification for the sample sizePlans for statistical or qualitative analysisPlans for dissemination of results
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Step 5: Create research proposal
Create a research proposal that will enable people who are not involved in the study to understand exactly what you plan to do
A proposal will be required when seeking departmental approval, applying for grant funding, and for ethics review
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Step 5: Create research proposal
Your proposal should include: Abstract background information goals & objectives & hypotheses justification & relevance research design, subjects, measures, data collection procedure, sample size justification, data analysis plan KT plan (may include budget + other sections)
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Step 6: Applying for grant funding
It is often possible to gain funding to assist in carrying out your research study
Funders will require a detailed research proposal
Consult with the FH Health Research Intelligence Unit early in the process to help identify potential grants as well as help prepare applications
Contact Magdalena Swanson, Research and Grant Development Facilitator for further information regarding grant writing [email protected]
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Step 7: Ethics approval
Ethics consideration is an essential component of the research process Most studies require ethics approval when dealing with human subjects or health dataThe Fraser Health Research Ethics Board (REB) reviews submissions on a regular basis See the Fraser Health Research homepage for more information and guidelines
http://research.fraserhealth.ca
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Step 8: Collect and analyze data
Collecting data for your study is exciting because you are close to finding out the answer to your research question or hypothesis Remember to be diligent and follow your research plan for collecting data Exercise care in the collecting, coding and documentation of data Analysis of data should follow the plan outlined in your proposal
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Step 9: Draw conclusions and relate findings
Summarize your findings and formulate conclusions Was your research question answered? Why do you think this was the case? What were the limitations of your study? What new information was gained that would inform future research?Prepare presentation, poster and / or manuscripts, liaise with stakeholders, etc.
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Research Process1. Generate idea2. Conduct literature review3. Refine research question4. Plan research methodology5. Create research proposal6. Apply for funding7. Apply for ethics approval8. Collect and analyze data9. Draw conclusions and relate findings
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Generating, Assessing and Refining the Research Question
“You can tell whether a man is clever by his answers. You can tell whether a man is wise by his questions."Naguib Mahfouz
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Generate Research Idea
Research begins with the identification of a problem/knowledge gap and formulation of a research question
Identifying this problem can be the hardest part of researchThe problem or question does not have to be complex
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Generate Research Idea
Where to obtain a research ideaExperience in your area of specialtyKnowledge of the relevant literature and issuesPractice guidelinesJournal editorials and review articlesDepartment strategic prioritiesPeers
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Group Exercise 1: Generating the research question
Working in small groups, come up with 2 research questions or topics of interest to you
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Assessing the Goal
What is your primary goal?Describe – when little is known about the characteristics of a problem, patient group, health care providers or a health service/systemAssociate – when you want to asses if certain factors might go hand in hand with a well described problem
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Assessing the GoalWhat is your primary goal?
Predict – when you want to understand the extent to which certain factors contribute to or cause a problemCompare – when you wish to assess the impact of an intervention or to determine if there are differences between interventions or characteristics of various groups (eg., differences between patients or health services)
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Building a Program of ResearchState of Knowledge
Type of Research Question
Examples
Problem is new or characteristics of problem not well defined.
Describe What are the characteristics? To what extent is this observed? What are the experiences?
Possible linkages between problem and other relevant factors.
Associate Is there an association?What are the correlates?
Determine the extent to which other characteristics influences the problem.
Predict What are the predictors?What are possible causes?
Identify differences between groups.Determine effects of interventions.
Compare Do differences exist?Is the treatment effective?Does the condition change over time?
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Group Exercise 2: Assessing the goal
Working in your groups, examine your list of research ideas/questions and assess how they fit with the four main goals of describe, associate, predict and compare
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Refining the Research Question
P Population/PatientI InterventionC ComparisonO Outcome
Define the key components of the question
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PICO – Population/PatientGenderAgeSocio-demographicDiagnostic categoryMedical historyInpatient or outpatient
Example: Adults in BC with diabetes
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PICO – Intervention/Exposure
ProphylacticTherapeuticDiagnostic testExposurePrognostic factorHealth servicePolicy change
Example: Lifestyle education and fitness training
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PICO – Comparisons
Alternative Population/Patient/Problem or Intervention to compare with the intervention being assessed
PlaceboAlternate medication, dose, timing of interventionUnexposed groupDifferent patient groupDifferent service, structure or policy
Example: Medication for obesity
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PICO – Outcome (quantitative)Concept
Symptoms, adverse events, functioning, quality of lifeMeasure
Categorical - eg) yes/no, occupations, body systemsOrdinal - implied order eg) income categories of low, medium, highInterval - Equal distance between each value eg) age, quantitative lab values, heart rate
Direction/ThresholdImprove, reduce, meet diagnostic cut-off
Example: Decrease in obesity in BC
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PICO and Research Question Type
Population/Patient
Intervention Comparison Outcome
Describe Always Sometimes Sometimes Sometimes
Associate Always Sometimes Sometimes Sometimes
Predict Always Sometimes Sometimes Always
Compare Always Sometimes Always Sometimes
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Qualitative Research
Qualitative account of:Experiences, perceptions, feelings, observationsFocus on what, how, why and when rather than how many or how much
May need to adapt PICO to account for qualitative outcomes
Example: How do patients with diabetes feel about interactions with clinical nutritionists?
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SPICE
For qualitative research SPICE may be more useful: S ETTING P ERSPECTIVE I NTERVENTION/INTEREST C OMPARISON E VALUATION
http://www.jbiconnect.org/connect/info/about/jbi_ebhc_approach.php
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SPICESETTING – In acute care PERSPECTIVE – Patients with diabetes INTERVENTION/INTEREST – recommendations for weight management from cliniciansCOMPARISON – Not Applicable EVALUATION – perceptions
Example: What are the perceptions of patients with diabetes in acute care about information they receive from clinicians about managing their weight?
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Group Exercise 3: Refining the Research Question
P Population/PatientI InterventionC ComparisonO Outcome
S SettingP PerspectiveI Intervention/InterestC ComparisonE Evaluation
Choose one research question and refine using PICO or SPICE
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Assessing Your Research Question
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Make it FINER
Confirmed through literature search and review
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Just for Fun – Is this FINER?Ig Nobel prize winner:MEDICINE: Donald L. Unger, of Thousand
Oaks, California, USA, for investigating a possible cause of arthritis of the fingers, by diligently cracking the knuckles of his left hand — but never cracking the knuckles of his right hand — every day for more than sixty (60) years.
REFERENCE: "Does Knuckle Cracking Lead to Arthritis of the Fingers?", Donald L. Unger, Arthritis and Rheumatism, vol. 41, no. 5, 1998, pp. 949-50.
http://improbable.com/ig/ig-pastwinners.hthttp://improbable.com/ig/winners/#ig2010ml
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MEDICINE: Brian Witcombe of Gloucester, UK, and Dan Meyer of Antioch, Tennessee, USA, for their penetrating medical report "Sword Swallowing and Its Side Effects."
REFERENCE: "Sword Swallowing and Its Side Effects," Brian Witcombeand Dan Meyer, British Medical Journal, December 23, 2006, vol. 333, pp. 1285-7
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Group Exercise 4 – Assessing your research question
Assess your research question according to FINER criteria
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Obtain Feedback
Write down your research questionPrepare a 1 or 2 page summary of the rationale and draft research planObtain feedback from peers, colleagues, decision makersSeek consultation with Evaluation and Research Services
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Plan research methodology
Inappropriate research design and method
Invalid results
Create research proposal
Not feasibleNot innovativeNot novel
Apply for funding Research budgets are determined by method
Does not pass expert peer review
Consequences of Poorly Formed or Poorly Informed Research Question
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Apply for ethics approval
Lack of equipoiseInappropriate methodsLack of confidentialityNeed for informed consent
Collect and analyze data
Collect incorrect dataMiscode dataChoose wrong analysis
Draw conclusions and relate findings
Conclusions invalidNot publishableNot useable
Consequences of Poorly Formed or Poorly Informed Research Question
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Questions